Danio rerio

15 known processes

ntn4

netrin 4

ntn4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vasculature development GO:0001944 278 0.458
blood vessel development GO:0001568 246 0.436
sprouting angiogenesis GO:0002040 53 0.290
angiogenesis GO:0001525 158 0.187
lymph vessel development GO:0001945 27 0.149
blood vessel morphogenesis GO:0048514 216 0.139
lymphangiogenesis GO:0001946 25 0.115
regulation of cell matrix adhesion GO:0001952 1 0.104
tube morphogenesis GO:0035239 349 0.103
segmentation GO:0035282 97 0.101
blood vessel endothelial cell migration GO:0043534 18 0.096
cell substrate adhesion GO:0031589 4 0.095
lymph vessel morphogenesis GO:0036303 25 0.094
epithelial cell migration GO:0010631 25 0.068
cell projection assembly GO:0030031 64 0.067
morphogenesis of an epithelium GO:0002009 333 0.057
i kappab kinase nf kappab signaling GO:0007249 4 0.057
embryo development ending in birth or egg hatching GO:0009792 271 0.055
signal transduction GO:0007165 455 0.054
phagocytosis GO:0006909 3 0.053
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.045
regulation of mononuclear cell migration GO:0071675 1 0.043
cell matrix adhesion GO:0007160 4 0.042
patterning of blood vessels GO:0001569 15 0.041
immune system process GO:0002376 241 0.041
cellular amine metabolic process GO:0044106 2 0.039
regulation of multicellular organismal development GO:2000026 223 0.039
negative regulation of metabolic process GO:0009892 86 0.039
somite development GO:0061053 96 0.039
osteoclast development GO:0036035 1 0.038
xanthophore differentiation GO:0050936 3 0.037
smooth muscle contraction GO:0006939 2 0.036
macrophage chemotaxis GO:0048246 3 0.036
nitrogen compound metabolic process GO:0006807 319 0.036
ameboidal type cell migration GO:0001667 143 0.035
renal system development GO:0072001 94 0.035
positive regulation of biological process GO:0048518 253 0.034
amine metabolic process GO:0009308 2 0.034
epithelial tube morphogenesis GO:0060562 148 0.033
regulation of retina development in camera type eye GO:1902866 2 0.033
extrinsic apoptotic signaling pathway GO:0097191 3 0.032
cellular component assembly GO:0022607 170 0.032
positive regulation of cellular catabolic process GO:0031331 3 0.032
establishment of localization GO:0051234 244 0.032
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.031
regulation of response to stimulus GO:0048583 269 0.031
determination of left right symmetry GO:0007368 179 0.030
positive regulation of stress activated mapk cascade GO:0032874 3 0.030
tissue migration GO:0090130 37 0.030
guanosine containing compound metabolic process GO:1901068 4 0.029
positive regulation of signal transduction GO:0009967 56 0.028
endothelial cell migration GO:0043542 19 0.028
regulation of cellular metabolic process GO:0031323 320 0.028
heart development GO:0007507 313 0.028
negative regulation of cellular process GO:0048523 283 0.028
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.028
regulation of cellular amino acid metabolic process GO:0006521 0 0.028
gastrulation GO:0007369 208 0.027
epithelium migration GO:0090132 25 0.027
regulation of cellular amine metabolic process GO:0033238 0 0.027
regulation of neural retina development GO:0061074 2 0.026
regulation of heart contraction GO:0008016 32 0.026
endothelial cell proliferation GO:0001935 11 0.026
chordate embryonic development GO:0043009 271 0.026
regulation of blood vessel size GO:0050880 2 0.026
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.026
guanosine containing compound catabolic process GO:1901069 2 0.025
negative regulation of protein kinase activity GO:0006469 4 0.024
positive regulation of phospholipase c activity GO:0010863 1 0.024
regulation of angiogenesis GO:0045765 26 0.024
cellular amino acid metabolic process GO:0006520 7 0.024
regulation of metabolic process GO:0019222 359 0.024
organic cyclic compound metabolic process GO:1901360 301 0.024
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.023
somitogenesis GO:0001756 87 0.023
vascular endothelial growth factor receptor signaling pathway GO:0048010 13 0.023
regulation of protein transport GO:0051223 3 0.023
response to external stimulus GO:0009605 264 0.023
peptidyl serine phosphorylation GO:0018105 1 0.023
protein localization to nucleus GO:0034504 3 0.023
cell surface receptor signaling pathway GO:0007166 325 0.023
single organism localization GO:1902578 225 0.022
cellular component movement GO:0006928 335 0.022
gene expression GO:0010467 252 0.022
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.022
positive regulation of catabolic process GO:0009896 4 0.022
heart morphogenesis GO:0003007 156 0.022
hemostasis GO:0007599 13 0.022
positive regulation of muscle cell differentiation GO:0051149 1 0.022
positive regulation of response to stimulus GO:0048584 80 0.022
positive regulation of leukocyte chemotaxis GO:0002690 1 0.022
system process GO:0003008 185 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.022
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.022
small molecule metabolic process GO:0044281 77 0.021
cellular nitrogen compound metabolic process GO:0034641 290 0.021
negative regulation of apoptotic process GO:0043066 55 0.021
aging GO:0007568 2 0.021
blood circulation GO:0008015 87 0.021
circulatory system process GO:0003013 87 0.021
digestive system development GO:0055123 289 0.021
positive regulation of leukocyte migration GO:0002687 2 0.021
regulation of establishment of protein localization GO:0070201 4 0.021
transcription dna templated GO:0006351 181 0.021
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.021
cellular ketone metabolic process GO:0042180 11 0.020
gtp catabolic process GO:0006184 2 0.020
regulation of tube size GO:0035150 2 0.020
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.020
protein secretion GO:0009306 1 0.020
cellular response to external stimulus GO:0071496 2 0.020
amino acid transport GO:0006865 2 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
positive regulation of retina development in camera type eye GO:1902868 1 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
positive regulation of immune effector process GO:0002699 3 0.019
cellular macromolecule metabolic process GO:0044260 391 0.019
hematopoietic or lymphoid organ development GO:0048534 191 0.019
convergent extension GO:0060026 118 0.019
positive regulation of gtp catabolic process GO:0033126 1 0.019
cranial ganglion development GO:0061550 3 0.019
regulation of multicellular organismal process GO:0051239 277 0.019
gland development GO:0048732 143 0.019
protein import GO:0017038 3 0.019
negative regulation of kinase activity GO:0033673 4 0.019
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.019
regulation of blood pressure GO:0008217 1 0.019
regulation of nucleocytoplasmic transport GO:0046822 2 0.018
heart contraction GO:0060047 71 0.018
organic substance biosynthetic process GO:1901576 289 0.018
blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:0002043 4 0.018
regulation of receptor mediated endocytosis GO:0048259 4 0.018
regulation of vasculature development GO:1901342 33 0.018
establishment of protein localization to organelle GO:0072594 4 0.018
inner ear development GO:0048839 126 0.018
neuroblast proliferation GO:0007405 2 0.018
positive regulation of transport GO:0051050 2 0.018
macromolecular complex subunit organization GO:0043933 74 0.017
anterior posterior pattern specification GO:0009952 152 0.017
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.017
regulation of synapse organization GO:0050807 3 0.017
heart process GO:0003015 71 0.017
vasculogenesis GO:0001570 41 0.017
stem cell proliferation GO:0072089 4 0.017
tissue remodeling GO:0048771 4 0.017
positive regulation of apoptotic signaling pathway GO:2001235 1 0.017
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
regulation of cell shape GO:0008360 1 0.017
inositol lipid mediated signaling GO:0048017 2 0.017
regulation of primary metabolic process GO:0080090 311 0.017
regulation of protein import into nucleus GO:0042306 2 0.017
positive regulation of protein kinase b signaling GO:0051897 1 0.017
regulation of epithelial cell proliferation GO:0050678 3 0.017
carboxylic acid metabolic process GO:0019752 22 0.016
phosphatidylinositol mediated signaling GO:0048015 2 0.016
melanocyte migration GO:0097324 4 0.016
cell migration involved in sprouting angiogenesis GO:0002042 8 0.016
cell death GO:0008219 121 0.016
locomotion GO:0040011 313 0.016
immune system development GO:0002520 191 0.016
regulation of endothelial cell proliferation GO:0001936 1 0.016
ubiquitin dependent protein catabolic process GO:0006511 3 0.016
regionalization GO:0003002 274 0.016
cardiac atrium development GO:0003230 4 0.016
apoptotic process GO:0006915 116 0.016
regulation of lipase activity GO:0060191 2 0.016
skeletal muscle tissue development GO:0007519 67 0.016
positive regulation of cellular process GO:0048522 201 0.016
response to stress GO:0006950 263 0.016
digestive tract morphogenesis GO:0048546 231 0.015
regulation of myotube differentiation GO:0010830 2 0.015
dicarboxylic acid transport GO:0006835 1 0.015
regulation of apoptotic process GO:0042981 98 0.015
cellular response to vascular endothelial growth factor stimulus GO:0035924 3 0.015
positive regulation of lipase activity GO:0060193 1 0.015
nuclear transport GO:0051169 4 0.015
cellular component biogenesis GO:0044085 178 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.014
regulation of protein targeting GO:1903533 2 0.014
actin mediated cell contraction GO:0070252 1 0.014
dorsal aorta morphogenesis GO:0035912 3 0.014
regulation of nitrogen compound metabolic process GO:0051171 251 0.014
skeletal muscle organ development GO:0060538 78 0.014
regulation of blood circulation GO:1903522 32 0.014
proteasomal protein catabolic process GO:0010498 2 0.014
meiotic nuclear division GO:0007126 4 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
sensory perception of chemical stimulus GO:0007606 3 0.014
muscle structure development GO:0061061 196 0.014
hypothalamus cell differentiation GO:0021979 4 0.014
organic acid metabolic process GO:0006082 31 0.014
cellular response to nutrient levels GO:0031669 2 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
gtp metabolic process GO:0046039 4 0.014
maintenance of location GO:0051235 4 0.014
regulation of programmed cell death GO:0043067 101 0.014
positive regulation of cell adhesion GO:0045785 1 0.014
regulation of inflammatory response GO:0050727 2 0.014
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
nucleocytoplasmic transport GO:0006913 4 0.013
death GO:0016265 121 0.013
blood vessel endothelial cell differentiation GO:0060837 2 0.013
signal transduction in absence of ligand GO:0038034 1 0.013
endothelial cell fate commitment GO:0060839 3 0.013
generation of neurons GO:0048699 385 0.013
protein homooligomerization GO:0051260 3 0.013
positive regulation of gtpase activity GO:0043547 1 0.013
embryonic organ development GO:0048568 381 0.013
negative regulation of epithelial cell proliferation GO:0050680 1 0.013
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.013
cytokinesis GO:0000910 3 0.013
neural retina development GO:0003407 49 0.013
wound healing GO:0042060 90 0.013
regulation of protein catabolic process GO:0042176 1 0.013
adherens junction organization GO:0034332 4 0.013
neurological system process GO:0050877 62 0.013
positive regulation of macrophage chemotaxis GO:0010759 1 0.013
oxoacid metabolic process GO:0043436 31 0.013
positive regulation of cellular component biogenesis GO:0044089 3 0.013
cellular nitrogen compound biosynthetic process GO:0044271 218 0.013
negative regulation of angiogenesis GO:0016525 7 0.013
reactive nitrogen species metabolic process GO:2001057 0 0.012
regulation of systemic arterial blood pressure GO:0003073 1 0.012
rna biosynthetic process GO:0032774 181 0.012
muscle organ development GO:0007517 101 0.012
heterocycle metabolic process GO:0046483 290 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.012
regulation of skeletal muscle tissue development GO:0048641 4 0.012
positive regulation of jnk cascade GO:0046330 3 0.012
nuclear import GO:0051170 3 0.012
regulation of cell communication GO:0010646 232 0.012
bmp signaling pathway GO:0030509 52 0.012
regulation of erk1 and erk2 cascade GO:0070372 4 0.012
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
negative regulation of protein phosphorylation GO:0001933 4 0.012
cell migration GO:0016477 237 0.012
lipid catabolic process GO:0016042 4 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
meiosis ii GO:0007135 1 0.012
positive regulation of stem cell proliferation GO:2000648 1 0.012
determination of bilateral symmetry GO:0009855 204 0.012
morphogenesis of an epithelial sheet GO:0002011 49 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
epidermal cell fate specification GO:0009957 4 0.011
direct ossification GO:0036072 3 0.011
lymphatic endothelial cell differentiation GO:0060836 1 0.011
regulation of cellular biosynthetic process GO:0031326 245 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.011
actin filament based movement GO:0030048 1 0.011
ear development GO:0043583 127 0.011
regulation of protein complex assembly GO:0043254 3 0.011
cardiac cell fate commitment GO:0060911 1 0.011
negative regulation of signaling GO:0023057 96 0.011
trabecula morphogenesis GO:0061383 2 0.011
protein complex subunit organization GO:0071822 46 0.011
regulation of cell death GO:0010941 103 0.011
cell substrate junction assembly GO:0007044 2 0.010
neuron differentiation GO:0030182 353 0.010
protein metabolic process GO:0019538 183 0.010
regulation of cytokine production GO:0001817 3 0.010
regulation of cellular component movement GO:0051270 55 0.010
cardiac atrium morphogenesis GO:0003209 2 0.010
adherens junction assembly GO:0034333 1 0.010
innate immune response GO:0045087 13 0.010
multi organism process GO:0051704 134 0.010
regulation of vasculogenesis GO:2001212 1 0.010
regulation of organ growth GO:0046620 3 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.010
ras protein signal transduction GO:0007265 7 0.010
phosphorylation GO:0016310 69 0.010
regulation of catalytic activity GO:0050790 55 0.010
positive regulation of cell activation GO:0050867 1 0.010
cytoskeleton organization GO:0007010 96 0.010

ntn4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.028
disease of anatomical entity DOID:7 0 0.028
sensory system disease DOID:0050155 0 0.012