Danio rerio

17 known processes

nyx

nyctalopin

nyx biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of epithelial cell polarity GO:0090162 2 0.166
central nervous system development GO:0007417 387 0.142
sensory organ development GO:0007423 393 0.142
regulation of synapse organization GO:0050807 3 0.119
protein targeting to membrane GO:0006612 1 0.078
camera type eye morphogenesis GO:0048593 108 0.073
camera type eye development GO:0043010 222 0.070
eye development GO:0001654 277 0.063
lateral inhibition GO:0046331 1 0.062
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.060
regulation of signaling GO:0023051 235 0.058
neurotransmitter transport GO:0006836 2 0.057
lipid storage GO:0019915 1 0.056
neuroblast proliferation GO:0007405 2 0.055
regulation of neurotransmitter secretion GO:0046928 1 0.052
stem cell proliferation GO:0072089 4 0.052
larval development GO:0002164 2 0.052
regulation of synapse assembly GO:0051963 3 0.051
forebrain cell migration GO:0021885 1 0.050
embryonic organ development GO:0048568 381 0.048
regulation of biological quality GO:0065008 263 0.048
response to ketone GO:1901654 1 0.048
regulation of neurotransmitter transport GO:0051588 1 0.046
regulation of guanylate cyclase activity GO:0031282 6 0.043
response to drug GO:0042493 3 0.042
positive regulation of cellular component biogenesis GO:0044089 3 0.041
sensory organ morphogenesis GO:0090596 200 0.040
immune system process GO:0002376 241 0.040
maintenance of location GO:0051235 4 0.039
cellular component assembly GO:0022607 170 0.038
retina development in camera type eye GO:0060041 146 0.038
regulation of cell projection assembly GO:0060491 4 0.037
detection of visible light GO:0009584 12 0.037
regulation of collateral sprouting in absence of injury GO:0048696 4 0.036
response to corticosteroid GO:0031960 1 0.035
eye morphogenesis GO:0048592 144 0.035
polarized epithelial cell differentiation GO:0030859 4 0.034
regulation of protein complex assembly GO:0043254 3 0.034
negative regulation of synapse assembly GO:0051964 2 0.034
axonogenesis GO:0007409 152 0.033
developmental cell growth GO:0048588 52 0.033
response to nutrient GO:0007584 3 0.033
response to vitamin GO:0033273 3 0.032
embryonic organ morphogenesis GO:0048562 274 0.032
cellular component biogenesis GO:0044085 178 0.031
positive regulation of synapse assembly GO:0051965 1 0.031
morphogenesis of an epithelium GO:0002009 333 0.031
phagocytosis GO:0006909 3 0.031
protein polymerization GO:0051258 4 0.031
apical junction assembly GO:0043297 1 0.031
cell projection organization GO:0030030 284 0.030
response to hexose GO:0009746 3 0.030
regulation of axonogenesis GO:0050770 32 0.029
endosomal transport GO:0016197 2 0.029
response to monosaccharide GO:0034284 3 0.029
monoamine transport GO:0015844 1 0.029
cellular component movement GO:0006928 335 0.029
glial cell migration GO:0008347 3 0.029
cellular carbohydrate metabolic process GO:0044262 4 0.029
cellular response to organic substance GO:0071310 105 0.028
epithelial tube morphogenesis GO:0060562 148 0.028
single organism localization GO:1902578 225 0.028
positive regulation of transport GO:0051050 2 0.028
response to chemical GO:0042221 320 0.027
regulation of cytokine production GO:0001817 3 0.027
retina layer formation GO:0010842 24 0.027
locomotion GO:0040011 313 0.027
axonal defasciculation GO:0007414 2 0.027
regulation of mrna processing GO:0050684 3 0.026
neuron differentiation GO:0030182 353 0.026
cell motility GO:0048870 244 0.026
transport GO:0006810 220 0.026
negative regulation of chemotaxis GO:0050922 4 0.026
antimicrobial humoral response GO:0019730 2 0.026
angiogenesis GO:0001525 158 0.026
photoreceptor cell differentiation GO:0046530 55 0.026
tube morphogenesis GO:0035239 349 0.025
positive regulation of secretion by cell GO:1903532 1 0.025
establishment of localization GO:0051234 244 0.025
neurotransmitter secretion GO:0007269 2 0.025
aging GO:0007568 2 0.025
cell migration GO:0016477 237 0.025
autophagy GO:0006914 4 0.024
digestive tract mesoderm development GO:0007502 1 0.024
single organism transport GO:0044765 206 0.024
nucleocytoplasmic transport GO:0006913 4 0.024
centrosome localization GO:0051642 1 0.024
neural retina development GO:0003407 49 0.024
heart morphogenesis GO:0003007 156 0.024
regulation of neurogenesis GO:0050767 87 0.023
protein localization to plasma membrane GO:0072659 1 0.023
neuron projection morphogenesis GO:0048812 161 0.023
response to glucose GO:0009749 3 0.023
regulation of multicellular organismal development GO:2000026 223 0.023
regulation of multicellular organism growth GO:0040014 4 0.023
ameboidal type cell migration GO:0001667 143 0.023
cell morphogenesis GO:0000902 289 0.023
outflow tract morphogenesis GO:0003151 1 0.023
synaptic growth at neuromuscular junction GO:0051124 2 0.022
cellular component maintenance GO:0043954 3 0.022
cellular component morphogenesis GO:0032989 336 0.022
regulation of inflammatory response GO:0050727 2 0.022
developmental growth GO:0048589 166 0.022
collateral sprouting in absence of injury GO:0048669 4 0.022
visual perception GO:0007601 17 0.022
response to carbohydrate GO:0009743 3 0.021
cortical cytoskeleton organization GO:0030865 1 0.021
neuron neuron synaptic transmission GO:0007270 1 0.021
female sex differentiation GO:0046660 4 0.021
endosome organization GO:0007032 2 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.021
localization of cell GO:0051674 244 0.021
single organism metabolic process GO:0044710 217 0.021
regulation of cgmp biosynthetic process GO:0030826 6 0.021
negative regulation of signal transduction GO:0009968 94 0.021
development of primary female sexual characteristics GO:0046545 4 0.021
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.021
brain development GO:0007420 293 0.021
regulation of primary metabolic process GO:0080090 311 0.020
rna localization GO:0006403 4 0.020
phasic smooth muscle contraction GO:0014821 1 0.020
regulation of protein polymerization GO:0032271 2 0.020
cognition GO:0050890 1 0.020
regulation of cell development GO:0060284 100 0.020
female gonad development GO:0008585 4 0.020
regionalization GO:0003002 274 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
tube closure GO:0060606 1 0.020
lytic vacuole organization GO:0080171 1 0.020
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.020
heart development GO:0007507 313 0.019
regulation of anatomical structure morphogenesis GO:0022603 130 0.019
actin filament polymerization GO:0030041 2 0.019
single organism membrane fusion GO:0044801 2 0.019
cgmp metabolic process GO:0046068 7 0.019
cellular response to nutrient levels GO:0031669 2 0.019
actin polymerization or depolymerization GO:0008154 2 0.019
cell projection morphogenesis GO:0048858 244 0.019
regulation of neuron migration GO:2001222 2 0.019
sensory perception of chemical stimulus GO:0007606 3 0.019
cellular response to extracellular stimulus GO:0031668 2 0.019
head development GO:0060322 303 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
rna 3 end processing GO:0031123 2 0.018
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.018
lens fiber cell morphogenesis GO:0070309 3 0.018
digestive tract morphogenesis GO:0048546 231 0.018
cell morphogenesis involved in differentiation GO:0000904 195 0.018
cyclic nucleotide metabolic process GO:0009187 18 0.018
apoptotic process involved in development GO:1902742 2 0.018
photoreceptor cell outer segment organization GO:0035845 9 0.018
regulation of multicellular organismal process GO:0051239 277 0.018
negative chemotaxis GO:0050919 1 0.018
response to glucocorticoid GO:0051384 1 0.018
central nervous system neuron differentiation GO:0021953 74 0.018
regulation of cell activation GO:0050865 1 0.018
protein heterooligomerization GO:0051291 1 0.018
lipid homeostasis GO:0055088 3 0.018
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.018
post embryonic organ development GO:0048569 4 0.018
regulation of cell differentiation GO:0045595 142 0.017
regulation of nervous system development GO:0051960 90 0.017
gastrulation GO:0007369 208 0.017
glucose homeostasis GO:0042593 1 0.017
growth GO:0040007 174 0.017
hematopoietic or lymphoid organ development GO:0048534 191 0.017
organelle fusion GO:0048284 3 0.017
cell death GO:0008219 121 0.017
positive regulation of cgmp biosynthetic process GO:0030828 6 0.017
response to lipid GO:0033993 60 0.017
positive regulation of secretion GO:0051047 1 0.017
determination of left right symmetry GO:0007368 179 0.017
regulation of mrna catabolic process GO:0061013 3 0.017
cellular amine metabolic process GO:0044106 2 0.017
sympathetic nervous system development GO:0048485 3 0.017
neuromuscular process controlling balance GO:0050885 3 0.017
cellular response to starvation GO:0009267 1 0.017
cell part morphogenesis GO:0032990 246 0.016
positive regulation of cell development GO:0010720 25 0.016
negative regulation of cellular process GO:0048523 283 0.016
positive regulation of cell cycle GO:0045787 3 0.016
cellular ketone metabolic process GO:0042180 11 0.016
negative regulation of protein phosphorylation GO:0001933 4 0.016
generation of neurons GO:0048699 385 0.016
phosphate containing compound metabolic process GO:0006796 108 0.016
vasculature development GO:0001944 278 0.016
determination of bilateral symmetry GO:0009855 204 0.016
synaptic vesicle localization GO:0097479 1 0.016
regulation of localization GO:0032879 104 0.016
exocytosis GO:0006887 1 0.016
nuclear transport GO:0051169 4 0.016
blood vessel morphogenesis GO:0048514 216 0.016
cortical actin cytoskeleton organization GO:0030866 1 0.016
ion transport GO:0006811 114 0.015
establishment of synaptic vesicle localization GO:0097480 1 0.015
regulation of response to stimulus GO:0048583 269 0.015
cell junction maintenance GO:0034331 2 0.015
positive regulation of developmental process GO:0051094 50 0.015
odontogenesis of dentin containing tooth GO:0042475 1 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
establishment of localization in cell GO:0051649 77 0.015
organelle organization GO:0006996 227 0.015
negative regulation of cell communication GO:0010648 96 0.015
macromolecular complex disassembly GO:0032984 1 0.015
gland development GO:0048732 143 0.015
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.015
cgmp biosynthetic process GO:0006182 7 0.015
positive regulation of protein complex assembly GO:0031334 2 0.015
inositol lipid mediated signaling GO:0048017 2 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.015
protein complex disassembly GO:0043241 1 0.015
synaptic vesicle transport GO:0048489 1 0.015
cellular component disassembly GO:0022411 1 0.015
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.015
blood circulation GO:0008015 87 0.015
digestive system development GO:0055123 289 0.015
negative regulation of defense response GO:0031348 2 0.015
determination of heart left right asymmetry GO:0061371 117 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
neuron development GO:0048666 262 0.014
regulation of glial cell differentiation GO:0045685 4 0.014
retina morphogenesis in camera type eye GO:0060042 79 0.014
glucose import GO:0046323 2 0.014
positive regulation of protein polymerization GO:0032273 2 0.014
cation transport GO:0006812 81 0.014
regulation of extent of cell growth GO:0061387 29 0.014
negative regulation of leukocyte migration GO:0002686 3 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
positive regulation of purine nucleotide biosynthetic process GO:1900373 8 0.014
detection of light stimulus GO:0009583 12 0.014
regulation of neuron differentiation GO:0045664 56 0.014
regulation of neuronal synaptic plasticity GO:0048168 1 0.014
guanosine containing compound catabolic process GO:1901069 2 0.014
adherens junction organization GO:0034332 4 0.014
regulation of nucleoside metabolic process GO:0009118 2 0.014
retinoic acid receptor signaling pathway GO:0048384 16 0.013
establishment of protein localization to plasma membrane GO:0090002 1 0.013
positive regulation of immune effector process GO:0002699 3 0.013
establishment of protein localization to organelle GO:0072594 4 0.013
primary neural tube formation GO:0014020 1 0.013
negative regulation of axon guidance GO:1902668 1 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
small molecule catabolic process GO:0044282 3 0.013
regulation of carbohydrate metabolic process GO:0006109 4 0.013
regulation of developmental process GO:0050793 247 0.013
programmed cell death GO:0012501 119 0.013
cartilage condensation GO:0001502 3 0.013
smooth muscle contraction GO:0006939 2 0.013
neural precursor cell proliferation GO:0061351 20 0.013
stem cell maintenance GO:0019827 4 0.013
immune system development GO:0002520 191 0.013
centrosome organization GO:0051297 1 0.013
negative regulation of catabolic process GO:0009895 3 0.013
response to organic cyclic compound GO:0014070 51 0.013
immunoglobulin mediated immune response GO:0016064 3 0.013
positive regulation of cell adhesion GO:0045785 1 0.013
developmental growth involved in morphogenesis GO:0060560 86 0.013
common bile duct development GO:0061009 13 0.013
cytokinesis GO:0000910 3 0.013
purine containing compound biosynthetic process GO:0072522 20 0.013
organic cyclic compound metabolic process GO:1901360 301 0.013
regulation of glucose import GO:0046324 1 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.013
lamellipodium organization GO:0097581 1 0.013
golgi vesicle transport GO:0048193 3 0.013
meiotic cell cycle process GO:1903046 3 0.013
gtp metabolic process GO:0046039 4 0.012
embryonic skeletal joint development GO:0072498 3 0.012
specification of symmetry GO:0009799 204 0.012
anion transport GO:0006820 38 0.012
nuclear export GO:0051168 1 0.012
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.012
cellular biosynthetic process GO:0044249 286 0.012
negative regulation of secretion GO:0051048 2 0.012
signal transduction GO:0007165 455 0.012
nucleobase containing compound metabolic process GO:0006139 274 0.012
establishment or maintenance of cell polarity GO:0007163 29 0.012
membrane invagination GO:0010324 1 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.012
axon development GO:0061564 166 0.012
mechanosensory behavior GO:0007638 2 0.012
interspecies interaction between organisms GO:0044419 4 0.012
regulation of metabolic process GO:0019222 359 0.012
multicellular organismal signaling GO:0035637 22 0.012
organic substance transport GO:0071702 58 0.012
detection of stimulus involved in sensory perception GO:0050906 21 0.012
peptidyl lysine acetylation GO:0018394 2 0.012
phosphatidylinositol mediated signaling GO:0048015 2 0.012
embryonic skeletal system morphogenesis GO:0048704 93 0.012
segmentation GO:0035282 97 0.012
translational initiation GO:0006413 3 0.012
amino acid transport GO:0006865 2 0.012
cellular protein catabolic process GO:0044257 4 0.012
regulation of synaptic plasticity GO:0048167 1 0.012
cell matrix adhesion GO:0007160 4 0.012
organonitrogen compound metabolic process GO:1901564 74 0.012
regulation of binding GO:0051098 3 0.012
establishment of cell polarity GO:0030010 18 0.012
camera type eye photoreceptor cell differentiation GO:0060219 19 0.012
cell surface receptor signaling pathway GO:0007166 325 0.011
regulation of developmental growth GO:0048638 38 0.011
compound eye development GO:0048749 2 0.011
single organism organelle organization GO:1902589 199 0.011
cellular response to external stimulus GO:0071496 2 0.011
regulation of purine nucleotide biosynthetic process GO:1900371 15 0.011
regulation of blood vessel size GO:0050880 2 0.011
mesoderm development GO:0007498 88 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
cellular nitrogen compound metabolic process GO:0034641 290 0.011
liver development GO:0001889 96 0.011
actin cytoskeleton organization GO:0030036 63 0.011
regulation of metal ion transport GO:0010959 4 0.011
heterocycle metabolic process GO:0046483 290 0.011
regulation of cell growth GO:0001558 29 0.011
regulation of cell communication GO:0010646 232 0.011
hemopoiesis GO:0030097 183 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
directional locomotion GO:0033058 1 0.011
nitrogen compound metabolic process GO:0006807 319 0.011
carbohydrate homeostasis GO:0033500 1 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
regulation of autophagy GO:0010506 3 0.011
single fertilization GO:0007338 3 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.011
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.011
sleep GO:0030431 1 0.011
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 11 0.011
negative regulation of biological process GO:0048519 304 0.011
response to external stimulus GO:0009605 264 0.011
small molecule metabolic process GO:0044281 77 0.011
neuron projection development GO:0031175 180 0.011
positive regulation of cytokine production GO:0001819 2 0.011
cell fate commitment GO:0045165 99 0.011
multicellular organism growth GO:0035264 4 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
lamellipodium assembly GO:0030032 1 0.011
regeneration GO:0031099 91 0.011
embryonic hemopoiesis GO:0035162 53 0.011
response to stress GO:0006950 263 0.011
regulation of cell shape GO:0008360 1 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
muscle system process GO:0003012 20 0.011
membrane fusion GO:0061025 2 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
telomere organization GO:0032200 1 0.011
positive regulation of guanylate cyclase activity GO:0031284 6 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
olfactory bulb development GO:0021772 4 0.011
regulation of hormone secretion GO:0046883 2 0.011
hormone transport GO:0009914 2 0.011
multi organism cellular process GO:0044764 2 0.011
positive regulation of nucleotide biosynthetic process GO:0030810 8 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
regulation of reproductive process GO:2000241 4 0.011
nephron tubule morphogenesis GO:0072078 1 0.011
macroautophagy GO:0016236 1 0.011
medulla oblongata development GO:0021550 4 0.010
mesenchyme development GO:0060485 127 0.010
cell substrate adhesion GO:0031589 4 0.010
nuclear migration GO:0007097 3 0.010
positive regulation of nucleotide catabolic process GO:0030813 1 0.010
regulation of tube size GO:0035150 2 0.010
cytoskeleton dependent cytokinesis GO:0061640 3 0.010
proteasomal protein catabolic process GO:0010498 2 0.010
positive regulation of catabolic process GO:0009896 4 0.010
embryonic heart tube development GO:0035050 133 0.010
mitochondrion organization GO:0007005 4 0.010
protein import into nucleus GO:0006606 3 0.010
calcium ion dependent exocytosis GO:0017156 1 0.010
pancreas development GO:0031016 84 0.010
regulation of neural precursor cell proliferation GO:2000177 3 0.010
establishment of apical basal cell polarity GO:0035089 2 0.010
cellular lipid catabolic process GO:0044242 3 0.010
negative regulation of dna metabolic process GO:0051053 4 0.010

nyx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.018
disease of metabolism DOID:0014667 0 0.018
inherited metabolic disorder DOID:655 0 0.018
disease of cellular proliferation DOID:14566 0 0.012
musculoskeletal system disease DOID:17 0 0.011