Danio rerio

0 known processes

opn1sw2

opsin 1 (cone pigments), short-wave-sensitive 2

(Aliases: zfblue,bluops,SI:zK13A21.5 (blue-sensitive opsin),SWS2)

opn1sw2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
phototransduction visible light GO:0007603 2 0.901
Zebrafish
detection of visible light GO:0009584 12 0.873
Zebrafish
photoperiodism GO:0009648 11 0.851
Zebrafish
rhodopsin mediated signaling pathway GO:0016056 1 0.840
Zebrafish
detection of stimulus GO:0051606 29 0.791
Zebrafish
response to light stimulus GO:0009416 46 0.789
Zebrafish
phototransduction GO:0007602 2 0.695
Zebrafish
g protein coupled receptor signaling pathway GO:0007186 74 0.606
Zebrafish
light absorption GO:0016037 2 0.565
Zebrafish
signal transduction GO:0007165 455 0.549
Zebrafish
response to abiotic stimulus GO:0009628 122 0.522
Zebrafish
negative regulation of sequestering of calcium ion GO:0051283 4 0.521
Zebrafish
sensory organ development GO:0007423 393 0.517
cellular response to radiation GO:0071478 4 0.433
Zebrafish
regulation of sequestering of calcium ion GO:0051282 4 0.419
Zebrafish
axon ensheathment in central nervous system GO:0032291 2 0.411
cellular response to light stimulus GO:0071482 4 0.349
Zebrafish
detection of light stimulus GO:0009583 12 0.327
Zebrafish
sequestering of calcium ion GO:0051208 3 0.304
Zebrafish
detection of external stimulus GO:0009581 24 0.304
Zebrafish
sequestering of metal ion GO:0051238 3 0.287
Zebrafish
cell surface receptor signaling pathway GO:0007166 325 0.287
Zebrafish
regulation of localization GO:0032879 104 0.283
Zebrafish
cellular nitrogen compound metabolic process GO:0034641 290 0.278
regulation of metabolic process GO:0019222 359 0.265
detection of abiotic stimulus GO:0009582 24 0.248
Zebrafish
response to light intensity GO:0009642 1 0.213
absorption of visible light GO:0016038 2 0.204
Zebrafish
digestive tract development GO:0048565 265 0.199
nitrogen compound metabolic process GO:0006807 319 0.189
eye development GO:0001654 277 0.181
response to external stimulus GO:0009605 264 0.170
Zebrafish
regulation of cell communication GO:0010646 232 0.168
regulation of primary metabolic process GO:0080090 311 0.166
maintenance of location GO:0051235 4 0.164
Zebrafish
establishment of endothelial barrier GO:0061028 3 0.158
regulation of cellular metabolic process GO:0031323 320 0.154
sensory organ morphogenesis GO:0090596 200 0.152
digestive tract morphogenesis GO:0048546 231 0.152
stem cell division GO:0017145 1 0.146
heterocycle metabolic process GO:0046483 290 0.143
protein modification process GO:0036211 100 0.141
transmission of nerve impulse GO:0019226 19 0.135
cellular cation homeostasis GO:0030003 17 0.132
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.130
regulation of biological quality GO:0065008 263 0.130
Zebrafish
sensory perception of light stimulus GO:0050953 19 0.129
digestive system development GO:0055123 289 0.128
regulation of inflammatory response GO:0050727 2 0.126
response to radiation GO:0009314 51 0.124
Zebrafish
gastrulation GO:0007369 208 0.122
organelle organization GO:0006996 227 0.119
ion homeostasis GO:0050801 41 0.117
Zebrafish
cation homeostasis GO:0055080 33 0.116
Zebrafish
negative regulation of protein phosphorylation GO:0001933 4 0.115
light induced release of internally sequestered calcium ion GO:0008377 1 0.114
Zebrafish
vasculature development GO:0001944 278 0.112
photoreceptor cell differentiation GO:0046530 55 0.112
protein metabolic process GO:0019538 183 0.111
meiotic nuclear division GO:0007126 4 0.106
neurological system process GO:0050877 62 0.105
cellular nitrogen compound biosynthetic process GO:0044271 218 0.103
eye morphogenesis GO:0048592 144 0.103
organic substance biosynthetic process GO:1901576 289 0.101
homeostatic process GO:0042592 142 0.100
Zebrafish
calcium ion homeostasis GO:0055074 19 0.100
Zebrafish
cellular calcium ion homeostasis GO:0006874 13 0.098
Zebrafish
single organism organelle organization GO:1902589 199 0.095
aging GO:0007568 2 0.091
neuron differentiation GO:0030182 353 0.090
phosphate containing compound metabolic process GO:0006796 108 0.090
cellular macromolecule metabolic process GO:0044260 391 0.088
nucleobase containing compound metabolic process GO:0006139 274 0.088
metal ion homeostasis GO:0055065 26 0.086
Zebrafish
heterocycle biosynthetic process GO:0018130 215 0.084
regulation of signal transduction GO:0009966 225 0.083
camera type eye morphogenesis GO:0048593 108 0.082
regulation of binding GO:0051098 3 0.082
nucleobase containing compound biosynthetic process GO:0034654 205 0.081
generation of neurons GO:0048699 385 0.080
photoreceptor cell development GO:0042461 40 0.079
cellular protein metabolic process GO:0044267 129 0.076
angiogenesis GO:0001525 158 0.073
light adaption GO:0036367 1 0.073
establishment of organelle localization GO:0051656 45 0.072
small molecule metabolic process GO:0044281 77 0.072
regulation of gene expression GO:0010468 265 0.072
cellular ion homeostasis GO:0006873 17 0.071
Zebrafish
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.071
nucleic acid metabolic process GO:0090304 244 0.070
cortical cytoskeleton organization GO:0030865 1 0.067
gene expression GO:0010467 252 0.067
positive regulation of cgmp biosynthetic process GO:0030828 6 0.066
positive regulation of cell division GO:0051781 2 0.066
mitotic cell cycle GO:0000278 64 0.066
response to wounding GO:0009611 116 0.064
retina development in camera type eye GO:0060041 146 0.063
negative regulation of cellular process GO:0048523 283 0.063
Zebrafish
blood vessel development GO:0001568 246 0.062
negative regulation of cell cell adhesion mediated by cadherin GO:2000048 2 0.062
organonitrogen compound metabolic process GO:1901564 74 0.062
response to drug GO:0042493 3 0.061
macromolecule modification GO:0043412 111 0.060
transport GO:0006810 220 0.060
nucleocytoplasmic transport GO:0006913 4 0.059
cytokinesis GO:0000910 3 0.058
negative regulation of biological process GO:0048519 304 0.056
Zebrafish
regulation of rna biosynthetic process GO:2001141 213 0.055
biosynthetic process GO:0009058 294 0.055
camera type eye development GO:0043010 222 0.054
cellular protein modification process GO:0006464 100 0.054
stem cell proliferation GO:0072089 4 0.054
sensory perception of chemical stimulus GO:0007606 3 0.053
cellular component movement GO:0006928 335 0.053
epiboly GO:0090504 41 0.053
nuclear transport GO:0051169 4 0.052
single organism metabolic process GO:0044710 217 0.052
system process GO:0003008 185 0.052
regulation of signaling GO:0023051 235 0.050
regulation of response to stimulus GO:0048583 269 0.050
cellular aromatic compound metabolic process GO:0006725 295 0.050
cellular biosynthetic process GO:0044249 286 0.049
amine metabolic process GO:0009308 2 0.048
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.048
ameboidal type cell migration GO:0001667 143 0.047
calcium mediated signaling GO:0019722 2 0.047
heart development GO:0007507 313 0.046
developmental growth GO:0048589 166 0.046
divalent inorganic cation homeostasis GO:0072507 22 0.046
Zebrafish
regulation of membrane potential GO:0042391 23 0.046
chemical homeostasis GO:0048878 49 0.046
Zebrafish
regulation of cellular biosynthetic process GO:0031326 245 0.046
locomotion GO:0040011 313 0.045
response to uv GO:0009411 3 0.045
phosphorus metabolic process GO:0006793 109 0.044
localization of cell GO:0051674 244 0.044
morphogenesis of an epithelium GO:0002009 333 0.044
neuron development GO:0048666 262 0.043
regulation of macromolecule metabolic process GO:0060255 317 0.042
cell migration GO:0016477 237 0.042
eye photoreceptor cell differentiation GO:0001754 45 0.042
regulation of cell death GO:0010941 103 0.041
carboxylic acid metabolic process GO:0019752 22 0.041
regulation of cellular amine metabolic process GO:0033238 0 0.040
brain development GO:0007420 293 0.040
negative regulation of homeostatic process GO:0032845 5 0.040
Zebrafish
organic acid metabolic process GO:0006082 31 0.040
entrainment of circadian clock by photoperiod GO:0043153 1 0.039
cellular metal ion homeostasis GO:0006875 16 0.039
Zebrafish
cell migration involved in gastrulation GO:0042074 79 0.039
neurotransmitter secretion GO:0007269 2 0.039
ear development GO:0043583 127 0.038
regulation of receptor recycling GO:0001919 3 0.038
regulation of macromolecule biosynthetic process GO:0010556 225 0.038
negative regulation of cellular metabolic process GO:0031324 77 0.037
meiotic cell cycle process GO:1903046 3 0.037
muscle organ development GO:0007517 101 0.037
cellular amine metabolic process GO:0044106 2 0.037
vascular endothelial growth factor receptor signaling pathway GO:0048010 13 0.037
posterior lateral line development GO:0048916 38 0.037
morphogenesis of an epithelial sheet GO:0002011 49 0.037
asymmetric protein localization GO:0008105 6 0.037
single organism localization GO:1902578 225 0.036
muscle cell development GO:0055001 115 0.035
cellular protein catabolic process GO:0044257 4 0.035
cellular chemical homeostasis GO:0055082 17 0.035
Zebrafish
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.034
cell fate commitment GO:0045165 99 0.034
regulation of protein transport GO:0051223 3 0.033
tissue remodeling GO:0048771 4 0.033
blood vessel morphogenesis GO:0048514 216 0.033
establishment of localization GO:0051234 244 0.032
macromolecule biosynthetic process GO:0009059 227 0.032
circadian sleep wake cycle process GO:0022410 2 0.031
negative regulation of kinase activity GO:0033673 4 0.031
cellular amino acid metabolic process GO:0006520 7 0.031
inner ear development GO:0048839 126 0.031
mechanosensory lateral line system development GO:0048881 49 0.031
immune system process GO:0002376 241 0.030
negative regulation of defense response GO:0031348 2 0.030
cgmp metabolic process GO:0046068 7 0.030
protein modification by small protein removal GO:0070646 1 0.029
specification of symmetry GO:0009799 204 0.029
regulation of protein metabolic process GO:0051246 56 0.029
proteasomal protein catabolic process GO:0010498 2 0.028
mitotic cell cycle process GO:1903047 48 0.028
cellular macromolecule biosynthetic process GO:0034645 224 0.028
negative regulation of protein kinase activity GO:0006469 4 0.028
receptor recycling GO:0001881 4 0.028
organic substance catabolic process GO:1901575 28 0.028
cellular component biogenesis GO:0044085 178 0.027
eye photoreceptor cell development GO:0042462 30 0.027
ubiquitin dependent protein catabolic process GO:0006511 3 0.027
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.027
growth GO:0040007 174 0.026
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.026
negative regulation of macromolecule metabolic process GO:0010605 76 0.026
multicellular organism growth GO:0035264 4 0.026
regulation of cellular ketone metabolic process GO:0010565 7 0.026
cortical actin cytoskeleton organization GO:0030866 1 0.026
intracellular signal transduction GO:0035556 85 0.026
neuroblast proliferation GO:0007405 2 0.025
regulation of cell motility GO:2000145 46 0.025
positive regulation of transport GO:0051050 2 0.025
cellular divalent inorganic cation homeostasis GO:0072503 13 0.025
Zebrafish
protein desumoylation GO:0016926 1 0.025
positive regulation of cellular process GO:0048522 201 0.025
positive regulation of cell cycle GO:0045787 3 0.025
regulation of establishment of protein localization GO:0070201 4 0.025
regulation of nitrogen compound metabolic process GO:0051171 251 0.025
regulation of nucleocytoplasmic transport GO:0046822 2 0.024
visual perception GO:0007601 17 0.024
regulation of rna metabolic process GO:0051252 224 0.024
negative regulation of response to stimulus GO:0048585 104 0.024
cellular homeostasis GO:0019725 26 0.024
Zebrafish
regulation of intracellular protein transport GO:0033157 3 0.024
photoreceptor cell outer segment organization GO:0035845 9 0.024
glial cell differentiation GO:0010001 42 0.023
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.023
cellular ketone metabolic process GO:0042180 11 0.023
cell migration involved in heart development GO:0060973 22 0.023
inositol lipid mediated signaling GO:0048017 2 0.023
organelle localization GO:0051640 49 0.023
chordate embryonic development GO:0043009 271 0.023
negative regulation of signaling GO:0023057 96 0.023
regulation of catalytic activity GO:0050790 55 0.023
cell motility GO:0048870 244 0.023
microtubule based process GO:0007017 60 0.022
rna biosynthetic process GO:0032774 181 0.022
sensory perception GO:0007600 39 0.022
cellular component morphogenesis GO:0032989 336 0.022
regulation of guanylate cyclase activity GO:0031282 6 0.022
developmental growth involved in morphogenesis GO:0060560 86 0.022
regulation of cellular component organization GO:0051128 86 0.021
regulation of nucleoside metabolic process GO:0009118 2 0.021
phosphorylation GO:0016310 69 0.021
organophosphate metabolic process GO:0019637 37 0.021
regulation of cytoplasmic transport GO:1903649 4 0.021
retina morphogenesis in camera type eye GO:0060042 79 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
regulation of cellular protein metabolic process GO:0032268 52 0.021
nucleic acid templated transcription GO:0097659 181 0.021
regulation of chemokine activity GO:1900136 3 0.021
regulation of transcription dna templated GO:0006355 213 0.021
rho protein signal transduction GO:0007266 5 0.020
regulation of growth rate GO:0040009 1 0.020
locomotor rhythm GO:0045475 3 0.020
inner ear morphogenesis GO:0042472 63 0.020
neural precursor cell proliferation GO:0061351 20 0.020
negative regulation of signal transduction GO:0009968 94 0.019
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.019
behavior GO:0007610 74 0.019
pyruvate metabolic process GO:0006090 1 0.019
multicellular organismal signaling GO:0035637 22 0.019
regulation of biosynthetic process GO:0009889 250 0.019
lateral line development GO:0048882 66 0.019
carbohydrate homeostasis GO:0033500 1 0.019
locomotory behavior GO:0007626 34 0.018
neuron neuron synaptic transmission GO:0007270 1 0.018
negative regulation of transcription dna templated GO:0045892 45 0.018
amino acid transport GO:0006865 2 0.018
transcription dna templated GO:0006351 181 0.018
head development GO:0060322 303 0.018
cell growth GO:0016049 57 0.018
response to chemical GO:0042221 320 0.018
ras protein signal transduction GO:0007265 7 0.018
regulation of nucleic acid templated transcription GO:1903506 213 0.018
meiosis i GO:0007127 1 0.018
modification dependent macromolecule catabolic process GO:0043632 3 0.018
muscle structure development GO:0061061 196 0.018
regulation of multicellular organism growth GO:0040014 4 0.017
positive regulation of catabolic process GO:0009896 4 0.017
multi organism process GO:0051704 134 0.017
cellular component assembly GO:0022607 170 0.017
gtp metabolic process GO:0046039 4 0.017
modification dependent protein catabolic process GO:0019941 3 0.017
zymogen activation GO:0031638 3 0.017
response to stress GO:0006950 263 0.017
embryonic organ morphogenesis GO:0048562 274 0.017
determination of bilateral symmetry GO:0009855 204 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
single organism biosynthetic process GO:0044711 71 0.016
aromatic compound biosynthetic process GO:0019438 217 0.016
small gtpase mediated signal transduction GO:0007264 8 0.016
establishment of synaptic vesicle localization GO:0097480 1 0.016
phagocytosis engulfment GO:0006911 1 0.016
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.016
negative regulation of programmed cell death GO:0043069 58 0.016
neurotransmitter transport GO:0006836 2 0.016
guanosine containing compound catabolic process GO:1901069 2 0.015
positive regulation of biological process GO:0048518 253 0.015
action potential GO:0001508 19 0.015
multicellular organismal homeostasis GO:0048871 29 0.015
phagocytosis GO:0006909 3 0.015
regulation of molecular function GO:0065009 70 0.015
negative regulation of phosphate metabolic process GO:0045936 13 0.015
regulation of phosphorus metabolic process GO:0051174 43 0.015
polyol metabolic process GO:0019751 1 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.015
regulation of cell migration GO:0030334 40 0.015
tube morphogenesis GO:0035239 349 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.015
membrane invagination GO:0010324 1 0.015
establishment of cell polarity GO:0030010 18 0.014
post embryonic morphogenesis GO:0009886 4 0.014
regulation of phosphate metabolic process GO:0019220 43 0.014
gtp catabolic process GO:0006184 2 0.014
posterior lateral line system development GO:0048915 46 0.014
anatomical structure homeostasis GO:0060249 36 0.014
chemosensory behavior GO:0007635 1 0.014
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.014
cell cycle GO:0007049 93 0.014
cell cycle process GO:0022402 53 0.014
protein import GO:0017038 3 0.014
cell cell adhesion mediated by cadherin GO:0044331 5 0.014
circadian sleep wake cycle GO:0042745 2 0.014
cell division GO:0051301 20 0.014
cilium organization GO:0044782 71 0.014
gastrulation with mouth forming second GO:0001702 44 0.014
establishment of spindle localization GO:0051293 12 0.014
regulation of cellular component movement GO:0051270 55 0.014
organic cyclic compound biosynthetic process GO:1901362 223 0.014
ribose phosphate metabolic process GO:0019693 27 0.014
negative regulation of metabolic process GO:0009892 86 0.013
regulation of dna replication GO:0006275 3 0.013
actin filament based process GO:0030029 64 0.013
endothelium development GO:0003158 25 0.013
positive regulation of inflammatory response GO:0050729 1 0.013
sensory system development GO:0048880 76 0.013
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
negative regulation of developmental process GO:0051093 65 0.013
regulation of multicellular organismal process GO:0051239 277 0.013
establishment of protein localization to organelle GO:0072594 4 0.013
positive regulation of map kinase activity GO:0043406 3 0.013
skeletal system development GO:0001501 181 0.013
adult behavior GO:0030534 2 0.013
regulation of programmed cell death GO:0043067 101 0.013
establishment of localization in cell GO:0051649 77 0.013
cellular response to abiotic stimulus GO:0071214 4 0.013
Zebrafish
peptidyl serine modification GO:0018209 2 0.013
establishment of endothelial blood brain barrier GO:0014045 2 0.013
macromolecular complex subunit organization GO:0043933 74 0.013
regulation of homeostatic process GO:0032844 9 0.013
Zebrafish
apical junction assembly GO:0043297 1 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
regulation of cell development GO:0060284 100 0.012
spermatid differentiation GO:0048515 2 0.012
regionalization GO:0003002 274 0.012
oxoacid metabolic process GO:0043436 31 0.012
organic substance transport GO:0071702 58 0.012
embryo development ending in birth or egg hatching GO:0009792 271 0.012
regulation of metal ion transport GO:0010959 4 0.012
fertilization GO:0009566 3 0.012
cell death GO:0008219 121 0.012
cellular localization GO:0051641 97 0.012
nuclear import GO:0051170 3 0.012
regulation of smoothened signaling pathway GO:0008589 18 0.012
lateral line system development GO:0048925 76 0.012
regulation of neuron differentiation GO:0045664 56 0.012
chromosome organization involved in meiosis GO:0070192 1 0.012
regulation of circadian rhythm GO:0042752 4 0.012
embryonic heart tube development GO:0035050 133 0.011
regulation of cell differentiation GO:0045595 142 0.011
regulation of organelle organization GO:0033043 29 0.011
establishment of blood brain barrier GO:0060856 2 0.011
regulation of circadian sleep wake cycle GO:0042749 1 0.011
regulation of chemotaxis GO:0050920 18 0.011
embryonic pattern specification GO:0009880 44 0.011
epithelial cell differentiation GO:0030855 116 0.011
synaptic transmission glycinergic GO:0060012 1 0.011
regulation of phosphorylation GO:0042325 26 0.011
negative regulation of map kinase activity GO:0043407 2 0.011
hormone secretion GO:0046879 2 0.011
nuclear division GO:0000280 23 0.011
regulation of protein modification process GO:0031399 29 0.011
dna metabolic process GO:0006259 27 0.011
atp catabolic process GO:0006200 4 0.011
hematopoietic or lymphoid organ development GO:0048534 191 0.011
olfactory bulb development GO:0021772 4 0.010
larval development GO:0002164 2 0.010
apical protein localization GO:0045176 6 0.010
actin filament bundle assembly GO:0051017 6 0.010
actomyosin structure organization GO:0031032 53 0.010
protein polymerization GO:0051258 4 0.010
enzyme linked receptor protein signaling pathway GO:0007167 106 0.010
regulation of hormone secretion GO:0046883 2 0.010
guanosine containing compound metabolic process GO:1901068 4 0.010
positive regulation of cell communication GO:0010647 56 0.010
positive regulation of cytoskeleton organization GO:0051495 3 0.010
regulation of meiotic cell cycle GO:0051445 1 0.010
regulation of cell cell adhesion GO:0022407 13 0.010
positive regulation of guanylate cyclase activity GO:0031284 6 0.010
regulation of translational initiation GO:0006446 1 0.010
response to carbohydrate GO:0009743 3 0.010
cellular response to external stimulus GO:0071496 2 0.010
anterior posterior pattern specification GO:0009952 152 0.010
regulation of protein binding GO:0043393 3 0.010
regulation of developmental process GO:0050793 247 0.010

opn1sw2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.296
disease of anatomical entity DOID:7 0 0.296
eye and adnexa disease DOID:1492 0 0.296
nervous system disease DOID:863 0 0.296
eye disease DOID:5614 0 0.296
retinal disease DOID:5679 0 0.167
retinal degeneration DOID:8466 0 0.037
retinitis pigmentosa DOID:10584 0 0.032
disease of metabolism DOID:0014667 0 0.013
immune system disease DOID:2914 0 0.012
anemia DOID:2355 0 0.012
hematopoietic system disease DOID:74 0 0.012