Danio rerio

14 known processes

otomp

otolith matrix protein

(Aliases: wu:fc44d11,zomp1,omp,omp-1,im:6904989)

otomp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rhombomere 5 development GO:0021571 4 0.282
liposaccharide metabolic process GO:1903509 8 0.270
sensory organ development GO:0007423 393 0.225
ganglioside metabolic process GO:0001573 3 0.169
glycolipid metabolic process GO:0006664 8 0.168
tissue remodeling GO:0048771 4 0.135
ceramide metabolic process GO:0006672 5 0.131
striated muscle cell differentiation GO:0051146 129 0.131
otolith development GO:0048840 32 0.130
notochord development GO:0030903 54 0.113
membrane lipid metabolic process GO:0006643 10 0.104
cilium morphogenesis GO:0060271 85 0.103
inner ear development GO:0048839 126 0.090
kupffer s vesicle development GO:0070121 50 0.089
detection of abiotic stimulus GO:0009582 24 0.076
negative regulation of protein phosphorylation GO:0001933 4 0.065
muscle structure development GO:0061061 196 0.064
camera type eye development GO:0043010 222 0.059
regulation of erk1 and erk2 cascade GO:0070372 4 0.059
signal transduction GO:0007165 455 0.055
skeletal system development GO:0001501 181 0.054
ear morphogenesis GO:0042471 64 0.053
eye development GO:0001654 277 0.051
single organism metabolic process GO:0044710 217 0.051
detection of mechanical stimulus involved in sensory perception GO:0050974 11 0.050
cell projection organization GO:0030030 284 0.049
multicellular organism growth GO:0035264 4 0.049
inner ear morphogenesis GO:0042472 63 0.048
regulation of gene expression GO:0010468 265 0.048
pectoral fin development GO:0033339 50 0.048
phosphorylation GO:0016310 69 0.047
regulation of cellular amine metabolic process GO:0033238 0 0.047
cell part morphogenesis GO:0032990 246 0.046
cellular amine metabolic process GO:0044106 2 0.046
blood vessel morphogenesis GO:0048514 216 0.045
determination of left right symmetry GO:0007368 179 0.045
cellular protein metabolic process GO:0044267 129 0.044
regulation of metal ion transport GO:0010959 4 0.044
cell projection morphogenesis GO:0048858 244 0.044
maintenance of location GO:0051235 4 0.043
generation of neurons GO:0048699 385 0.043
aging GO:0007568 2 0.041
otic vesicle development GO:0071599 42 0.041
ubiquitin dependent protein catabolic process GO:0006511 3 0.040
ear development GO:0043583 127 0.040
camera type eye morphogenesis GO:0048593 108 0.038
negative regulation of protein kinase activity GO:0006469 4 0.038
regulation of cell shape GO:0008360 1 0.038
regulation of reproductive process GO:2000241 4 0.038
positive regulation of cellular amine metabolic process GO:0033240 0 0.037
regulation of bone remodeling GO:0046850 2 0.037
developmental programmed cell death GO:0010623 4 0.037
nucleic acid templated transcription GO:0097659 181 0.036
fin morphogenesis GO:0033334 53 0.036
regulation of skeletal muscle tissue development GO:0048641 4 0.036
organonitrogen compound metabolic process GO:1901564 74 0.036
sensory perception of chemical stimulus GO:0007606 3 0.035
regulation of catalytic activity GO:0050790 55 0.035
cellular protein modification process GO:0006464 100 0.035
exocrine pancreas development GO:0031017 28 0.035
amine metabolic process GO:0009308 2 0.035
somite development GO:0061053 96 0.034
midbrain development GO:0030901 28 0.034
determination of bilateral symmetry GO:0009855 204 0.034
cellular amino acid metabolic process GO:0006520 7 0.033
muscle cell differentiation GO:0042692 139 0.033
mechanoreceptor differentiation GO:0042490 37 0.032
response to biotic stimulus GO:0009607 97 0.032
Zebrafish
cell migration GO:0016477 237 0.032
somatic muscle development GO:0007525 4 0.032
protein metabolic process GO:0019538 183 0.031
Zebrafish
sensory organ morphogenesis GO:0090596 200 0.031
blood vessel development GO:0001568 246 0.030
regulation of macromolecule metabolic process GO:0060255 317 0.030
cellular macromolecule metabolic process GO:0044260 391 0.029
Zebrafish
regulation of multicellular organism growth GO:0040014 4 0.029
chordate embryonic development GO:0043009 271 0.029
negative regulation of kinase activity GO:0033673 4 0.028
vasculature development GO:0001944 278 0.028
anterior posterior pattern specification GO:0009952 152 0.028
rhombomere development GO:0021546 19 0.028
organelle organization GO:0006996 227 0.028
regulation of developmental process GO:0050793 247 0.028
regulation of metabolic process GO:0019222 359 0.028
sensory system development GO:0048880 76 0.028
stem cell proliferation GO:0072089 4 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.027
regulation of establishment of protein localization GO:0070201 4 0.027
regulation of cellular ketone metabolic process GO:0010565 7 0.027
head development GO:0060322 303 0.026
angiogenesis GO:0001525 158 0.026
positive regulation of cellular component biogenesis GO:0044089 3 0.026
response to abiotic stimulus GO:0009628 122 0.026
positive regulation of muscle organ development GO:0048636 1 0.026
otic placode formation GO:0043049 23 0.026
bone remodeling GO:0046849 2 0.026
muscle organ development GO:0007517 101 0.025
startle response GO:0001964 4 0.025
segmentation GO:0035282 97 0.025
phosphate containing compound metabolic process GO:0006796 108 0.025
cardiac muscle tissue development GO:0048738 48 0.024
appendage development GO:0048736 80 0.024
regulation of endopeptidase activity GO:0052548 23 0.024
amino acid transport GO:0006865 2 0.024
positive regulation of response to stimulus GO:0048584 80 0.024
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.024
meiotic nuclear division GO:0007126 4 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.023
protein modification process GO:0036211 100 0.023
erk1 and erk2 cascade GO:0070371 4 0.023
response to chemical GO:0042221 320 0.023
neuron differentiation GO:0030182 353 0.023
pharyngeal system development GO:0060037 18 0.023
cellular protein catabolic process GO:0044257 4 0.023
sphingolipid metabolic process GO:0006665 9 0.022
positive regulation of epithelial cell migration GO:0010634 2 0.022
striated muscle cell development GO:0055002 108 0.022
posterior lateral line system development GO:0048915 46 0.022
gastrulation GO:0007369 208 0.022
pancreas development GO:0031016 84 0.022
cellular component movement GO:0006928 335 0.022
circadian regulation of gene expression GO:0032922 8 0.021
adult behavior GO:0030534 2 0.021
skeletal muscle tissue development GO:0007519 67 0.021
modification dependent protein catabolic process GO:0019941 3 0.021
cell substrate adhesion GO:0031589 4 0.021
rhombomere 6 development GO:0021572 4 0.021
regulation of protein transport GO:0051223 3 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
protein dephosphorylation GO:0006470 3 0.021
nucleobase containing compound biosynthetic process GO:0034654 205 0.021
localization of cell GO:0051674 244 0.021
locus ceruleus development GO:0021703 3 0.020
phosphorus metabolic process GO:0006793 109 0.020
rna metabolic process GO:0016070 219 0.020
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.020
lateral line development GO:0048882 66 0.020
stem cell division GO:0017145 1 0.020
detection of mechanical stimulus GO:0050982 11 0.020
positive regulation of striated muscle tissue development GO:0045844 1 0.019
regulation of cellular metabolic process GO:0031323 320 0.019
autophagy GO:0006914 4 0.019
cellular response to chemical stimulus GO:0070887 157 0.019
nuclear transport GO:0051169 4 0.019
centrosome organization GO:0051297 1 0.019
neuron development GO:0048666 262 0.019
specification of symmetry GO:0009799 204 0.019
regulation of protein ubiquitination GO:0031396 3 0.019
macromolecular complex subunit organization GO:0043933 74 0.019
cellular macromolecule biosynthetic process GO:0034645 224 0.019
Zebrafish
cellular ketone metabolic process GO:0042180 11 0.019
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.019
cell proliferation GO:0008283 80 0.019
regulation of transmembrane transporter activity GO:0022898 2 0.019
digestive system development GO:0055123 289 0.018
response to external stimulus GO:0009605 264 0.018
Zebrafish
cerebellum formation GO:0021588 2 0.018
epidermis development GO:0008544 48 0.018
regulation of macromolecule biosynthetic process GO:0010556 225 0.018
negative regulation of cellular process GO:0048523 283 0.018
limb bud formation GO:0060174 2 0.018
macromolecule biosynthetic process GO:0009059 227 0.018
Zebrafish
otic vesicle morphogenesis GO:0071600 34 0.018
growth GO:0040007 174 0.018
cellular component assembly GO:0022607 170 0.018
embryonic organ morphogenesis GO:0048562 274 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.018
exocrine system development GO:0035272 28 0.018
regulation of gastrulation GO:0010470 24 0.018
regulation of dna replication GO:0006275 3 0.018
organic acid metabolic process GO:0006082 31 0.018
retina morphogenesis in camera type eye GO:0060042 79 0.018
ribonucleoside monophosphate catabolic process GO:0009158 4 0.017
otic vesicle formation GO:0030916 27 0.017
regulation of response to stimulus GO:0048583 269 0.017
gene expression GO:0010467 252 0.017
response to hydrogen peroxide GO:0042542 3 0.017
enzyme linked receptor protein signaling pathway GO:0007167 106 0.017
positive regulation of cytoskeleton organization GO:0051495 3 0.017
phagocytosis engulfment GO:0006911 1 0.017
digestive tract development GO:0048565 265 0.017
ectodermal placode development GO:0071696 37 0.017
peptidyl serine phosphorylation GO:0018105 1 0.017
nucleocytoplasmic transport GO:0006913 4 0.017
cellular response to growth factor stimulus GO:0071363 39 0.017
positive regulation of cell cycle GO:0045787 3 0.017
mitochondrion organization GO:0007005 4 0.017
phagocytosis GO:0006909 3 0.017
cell motility GO:0048870 244 0.017
response to bacterium GO:0009617 58 0.017
Zebrafish
endocrine system development GO:0035270 65 0.017
hindbrain formation GO:0021576 3 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.016
vascular endothelial growth factor receptor signaling pathway GO:0048010 13 0.016
regulation of calcium ion transport GO:0051924 2 0.016
wnt signaling pathway GO:0016055 80 0.016
cardiac ventricle development GO:0003231 9 0.016
peptidyl serine modification GO:0018209 2 0.016
regulation of signaling GO:0023051 235 0.016
appendage morphogenesis GO:0035107 56 0.016
regulation of molecular function GO:0065009 70 0.016
synaptic growth at neuromuscular junction GO:0051124 2 0.016
erythrocyte homeostasis GO:0034101 55 0.016
positive regulation of map kinase activity GO:0043406 3 0.016
ovulation cycle process GO:0022602 2 0.016
positive regulation of transport GO:0051050 2 0.016
ion transport GO:0006811 114 0.016
Zebrafish
regulation of blood vessel size GO:0050880 2 0.016
digestive tract morphogenesis GO:0048546 231 0.016
somitogenesis GO:0001756 87 0.016
regulation of tube size GO:0035150 2 0.016
regulation of cellular protein metabolic process GO:0032268 52 0.015
cell matrix adhesion GO:0007160 4 0.015
atp catabolic process GO:0006200 4 0.015
negative regulation of metabolic process GO:0009892 86 0.015
regulation of ion transmembrane transporter activity GO:0032412 2 0.015
hormone transport GO:0009914 2 0.015
mesenchyme development GO:0060485 127 0.015
neurotransmitter transport GO:0006836 2 0.015
protein phosphorylation GO:0006468 47 0.015
erythrocyte development GO:0048821 24 0.015
carbohydrate homeostasis GO:0033500 1 0.015
regulation of protein complex assembly GO:0043254 3 0.015
embryonic heart tube development GO:0035050 133 0.015
cell surface receptor signaling pathway GO:0007166 325 0.015
regulation of primary metabolic process GO:0080090 311 0.015
cardiac chamber development GO:0003205 19 0.015
regulation of wnt signaling pathway GO:0030111 53 0.015
stem cell maintenance GO:0019827 4 0.015
skeletal muscle organ development GO:0060538 78 0.014
transport GO:0006810 220 0.014
Zebrafish
cellular component morphogenesis GO:0032989 336 0.014
regulation of tissue remodeling GO:0034103 2 0.014
regulation of cell migration GO:0030334 40 0.014
gland development GO:0048732 143 0.014
membrane invagination GO:0010324 1 0.014
ovulation cycle GO:0042698 2 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
exocytosis GO:0006887 1 0.014
regulation of cellular response to growth factor stimulus GO:0090287 35 0.014
muscle tissue development GO:0060537 110 0.014
lateral line system development GO:0048925 76 0.014
positive regulation of catabolic process GO:0009896 4 0.014
organic substance biosynthetic process GO:1901576 289 0.014
Zebrafish
regulation of cell communication GO:0010646 232 0.014
regulation of anatomical structure morphogenesis GO:0022603 130 0.014
neural nucleus development GO:0048857 15 0.014
regulation of intracellular signal transduction GO:1902531 57 0.014
posterior lateral line development GO:0048916 38 0.014
positive regulation of locomotion GO:0040017 14 0.014
cellular response to organic substance GO:0071310 105 0.014
adherens junction assembly GO:0034333 1 0.014
response to endogenous stimulus GO:0009719 83 0.014
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.014
hair cell differentiation GO:0035315 32 0.014
transcription dna templated GO:0006351 181 0.014
epithelial cell differentiation GO:0030855 116 0.014
sensory perception of mechanical stimulus GO:0050954 16 0.014
myeloid cell homeostasis GO:0002262 56 0.014
regulation of biosynthetic process GO:0009889 250 0.014
establishment of protein localization to organelle GO:0072594 4 0.014
macromolecule modification GO:0043412 111 0.014
response to alkaloid GO:0043279 2 0.014
cell morphogenesis GO:0000902 289 0.014
behavior GO:0007610 74 0.014
heart morphogenesis GO:0003007 156 0.013
regulation of transcription dna templated GO:0006355 213 0.013
cellular component disassembly GO:0022411 1 0.013
regulation of multicellular organismal process GO:0051239 277 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.013
positive regulation of biological process GO:0048518 253 0.013
morphogenesis of an epithelium GO:0002009 333 0.013
peripheral nervous system development GO:0007422 55 0.013
rna biosynthetic process GO:0032774 181 0.013
regulation of hormone secretion GO:0046883 2 0.013
organic cyclic compound metabolic process GO:1901360 301 0.013
neurological system process GO:0050877 62 0.013
regulation of cell fate specification GO:0042659 20 0.013
detection of external stimulus GO:0009581 24 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
heterocycle biosynthetic process GO:0018130 215 0.013
odontogenesis of dentin containing tooth GO:0042475 1 0.013
mitotic cell cycle process GO:1903047 48 0.013
positive regulation of cellular process GO:0048522 201 0.013
cellular response to external stimulus GO:0071496 2 0.013
regulation of binding GO:0051098 3 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
pectoral fin morphogenesis GO:0035138 29 0.013
multi organism process GO:0051704 134 0.013
Zebrafish
response to drug GO:0042493 3 0.013
larval development GO:0002164 2 0.013
nuclear export GO:0051168 1 0.013
negative regulation of cellular protein metabolic process GO:0032269 16 0.013
cellular nitrogen compound biosynthetic process GO:0044271 218 0.013
hindbrain development GO:0030902 91 0.013
determination of dorsal ventral asymmetry GO:0048262 34 0.013
locomotion GO:0040011 313 0.013
taxis GO:0042330 109 0.012
muscle cell development GO:0055001 115 0.012
retina development in camera type eye GO:0060041 146 0.012
protein localization to plasma membrane GO:0072659 1 0.012
skeletal system morphogenesis GO:0048705 102 0.012
cytokinesis GO:0000910 3 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
membrane fusion GO:0061025 2 0.012
thyroid gland development GO:0030878 12 0.012
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.012
activation of mapk activity GO:0000187 3 0.012
cardiocyte differentiation GO:0035051 44 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
protein stabilization GO:0050821 2 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
determination of heart left right asymmetry GO:0061371 117 0.012
oxoacid metabolic process GO:0043436 31 0.012
female gonad development GO:0008585 4 0.012
stem cell differentiation GO:0048863 117 0.012
regulation of nitrogen compound metabolic process GO:0051171 251 0.012
inner ear receptor cell differentiation GO:0060113 29 0.012
female sex differentiation GO:0046660 4 0.012
heart contraction GO:0060047 71 0.012
negative regulation of biological process GO:0048519 304 0.012
cardiac ventricle morphogenesis GO:0003208 7 0.012
negative regulation of epithelial cell proliferation GO:0050680 1 0.012
nucleic acid metabolic process GO:0090304 244 0.012
detection of stimulus involved in sensory perception GO:0050906 21 0.012
endoderm formation GO:0001706 29 0.012
positive regulation of metabolic process GO:0009893 108 0.012
regulation of synapse assembly GO:0051963 3 0.012
regulation of sodium ion transmembrane transport GO:1902305 1 0.011
regulation of blood pressure GO:0008217 1 0.011
meiotic cell cycle process GO:1903046 3 0.011
cell cycle GO:0007049 93 0.011
cellular lipid metabolic process GO:0044255 36 0.011
anion transport GO:0006820 38 0.011
embryonic organ development GO:0048568 381 0.011
cellular nitrogen compound metabolic process GO:0034641 290 0.011
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.011
regulation of programmed cell death GO:0043067 101 0.011
extrinsic apoptotic signaling pathway GO:0097191 3 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
cellular response to endogenous stimulus GO:0071495 68 0.011
heart development GO:0007507 313 0.011
single organism organelle organization GO:1902589 199 0.011
hormone biosynthetic process GO:0042446 3 0.011
hemopoiesis GO:0030097 183 0.011
central nervous system development GO:0007417 387 0.011
response to stress GO:0006950 263 0.011
immune system process GO:0002376 241 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
regulation of sodium ion transport GO:0002028 2 0.011
regulation of phosphorus metabolic process GO:0051174 43 0.011
positive regulation of skeletal muscle tissue development GO:0048643 1 0.011
single organism membrane fusion GO:0044801 2 0.011
regulation of embryonic development GO:0045995 47 0.011
calcium mediated signaling GO:0019722 2 0.011
intracellular signal transduction GO:0035556 85 0.011
protein localization to nucleus GO:0034504 3 0.011
system process GO:0003008 185 0.011
compound eye development GO:0048749 2 0.011
regulation of signal transduction GO:0009966 225 0.011
regulation of cell motility GO:2000145 46 0.011
regulation of organelle organization GO:0033043 29 0.011
ectodermal placode morphogenesis GO:0071697 32 0.011
positive regulation of secretion GO:0051047 1 0.011
positive regulation of protein complex assembly GO:0031334 2 0.011
actin filament polymerization GO:0030041 2 0.011
positive regulation of cell adhesion GO:0045785 1 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
cellular response to extracellular stimulus GO:0031668 2 0.011
regulation of rna biosynthetic process GO:2001141 213 0.010
negative regulation of dna replication GO:0008156 2 0.010
regulation of transporter activity GO:0032409 2 0.010
cellular component biogenesis GO:0044085 178 0.010
carbohydrate derivative metabolic process GO:1901135 61 0.010
cell death GO:0008219 121 0.010
fin development GO:0033333 77 0.010
glucose homeostasis GO:0042593 1 0.010
formation of primary germ layer GO:0001704 62 0.010
single organism cellular localization GO:1902580 46 0.010
transcription from rna polymerase ii promoter GO:0006366 80 0.010
regulation of localization GO:0032879 104 0.010
regulation of cell activation GO:0050865 1 0.010
actin filament based movement GO:0030048 1 0.010
eye morphogenesis GO:0048592 144 0.010
lipid storage GO:0019915 1 0.010
neuron fate commitment GO:0048663 26 0.010
purine nucleoside monophosphate catabolic process GO:0009128 4 0.010
regionalization GO:0003002 274 0.010
spermatid development GO:0007286 2 0.010
leukocyte proliferation GO:0070661 1 0.010
adherens junction organization GO:0034332 4 0.010
urogenital system development GO:0001655 97 0.010

otomp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.059
nervous system disease DOID:863 0 0.059
musculoskeletal system disease DOID:17 0 0.030
immune system disease DOID:2914 0 0.019
muscular disease DOID:0080000 0 0.013
sensory system disease DOID:0050155 0 0.012