Danio rerio

31 known processes

otx1b

orthodenticle homolog 1b

(Aliases: cb769,fj99f05,zOtx1,otx1,wu:fj99f05)

otx1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
central nervous system development GO:0007417 387 0.993
nucleobase containing compound biosynthetic process GO:0034654 205 0.984
organic cyclic compound metabolic process GO:1901360 301 0.979
cell proliferation in forebrain GO:0021846 3 0.977
rna metabolic process GO:0016070 219 0.970
heterocycle metabolic process GO:0046483 290 0.962
nucleic acid metabolic process GO:0090304 244 0.959
gene expression GO:0010467 252 0.948
regulation of primary metabolic process GO:0080090 311 0.933
heterocycle biosynthetic process GO:0018130 215 0.931
regulation of macromolecule biosynthetic process GO:0010556 225 0.925
cellular aromatic compound metabolic process GO:0006725 295 0.918
regulation of biosynthetic process GO:0009889 250 0.916
aromatic compound biosynthetic process GO:0019438 217 0.916
sensory organ morphogenesis GO:0090596 200 0.913
forebrain generation of neurons GO:0021872 14 0.906
regulation of nucleic acid templated transcription GO:1903506 213 0.901
neuron differentiation GO:0030182 353 0.901
forebrain regionalization GO:0021871 4 0.898
regulation of gene expression GO:0010468 265 0.875
cellular biosynthetic process GO:0044249 286 0.872
camera type eye morphogenesis GO:0048593 108 0.868
sensory organ development GO:0007423 393 0.857
forebrain development GO:0030900 96 0.853
forebrain anterior posterior pattern specification GO:0021797 3 0.847
forebrain neuron fate commitment GO:0021877 1 0.844
photoreceptor cell development GO:0042461 40 0.838
regulation of transcription dna templated GO:0006355 213 0.833
nucleobase containing compound metabolic process GO:0006139 274 0.830
segmentation GO:0035282 97 0.810
axon guidance GO:0007411 86 0.806
regulation of metabolic process GO:0019222 359 0.806
transcription dna templated GO:0006351 181 0.800
head development GO:0060322 303 0.787
cellular nitrogen compound metabolic process GO:0034641 290 0.786
photoreceptor cell differentiation GO:0046530 55 0.785
cellular component morphogenesis GO:0032989 336 0.776
diencephalon development GO:0021536 58 0.772
regulation of cellular biosynthetic process GO:0031326 245 0.770
regulation of inner ear receptor cell differentiation GO:2000980 1 0.766
negative regulation of gene expression GO:0010629 65 0.756
larval development GO:0002164 2 0.747
organic substance biosynthetic process GO:1901576 289 0.738
digestive tract development GO:0048565 265 0.731
endoderm development GO:0007492 49 0.725
organic cyclic compound biosynthetic process GO:1901362 223 0.723
regulation of macromolecule metabolic process GO:0060255 317 0.722
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.720
brain development GO:0007420 293 0.702
rna biosynthetic process GO:0032774 181 0.700
macromolecule biosynthetic process GO:0009059 227 0.673
camera type eye development GO:0043010 222 0.671
neuron development GO:0048666 262 0.670
eye development GO:0001654 277 0.663
digestive tract morphogenesis GO:0048546 231 0.660
chordate embryonic development GO:0043009 271 0.658
cellular macromolecule biosynthetic process GO:0034645 224 0.642
regulation of cellular metabolic process GO:0031323 320 0.636
nitrogen compound metabolic process GO:0006807 319 0.635
regionalization GO:0003002 274 0.630
regulation of rna metabolic process GO:0051252 224 0.608
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.607
nucleic acid templated transcription GO:0097659 181 0.598
response to chemical GO:0042221 320 0.584
regulation of mechanoreceptor differentiation GO:0045631 1 0.573
neuron fate determination GO:0048664 2 0.571
anterior posterior pattern specification GO:0009952 152 0.570
midbrain development GO:0030901 28 0.568
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.566
cell migration GO:0016477 237 0.566
localization of cell GO:0051674 244 0.562
heart looping GO:0001947 94 0.554
digestive system development GO:0055123 289 0.537
eye morphogenesis GO:0048592 144 0.525
limbic system development GO:0021761 16 0.523
eye photoreceptor cell differentiation GO:0001754 45 0.522
ear development GO:0043583 127 0.517
blood vessel morphogenesis GO:0048514 216 0.505
neural crest cell differentiation GO:0014033 72 0.501
axon development GO:0061564 166 0.491
wnt signaling pathway GO:0016055 80 0.487
negative regulation of nucleic acid templated transcription GO:1903507 45 0.483
morphogenesis of an epithelium GO:0002009 333 0.480
ectodermal placode development GO:0071696 37 0.479
regulation of multicellular organismal development GO:2000026 223 0.479
generation of neurons GO:0048699 385 0.474
neuron fate commitment GO:0048663 26 0.463
cell fate commitment GO:0045165 99 0.463
epidermal cell fate specification GO:0009957 4 0.459
biosynthetic process GO:0009058 294 0.456
cellular component movement GO:0006928 335 0.455
signal transduction GO:0007165 455 0.453
regulation of rna biosynthetic process GO:2001141 213 0.452
ameboidal type cell migration GO:0001667 143 0.450
determination of left right symmetry GO:0007368 179 0.443
cell surface receptor signaling pathway GO:0007166 325 0.441
blood vessel development GO:0001568 246 0.440
negative regulation of neuron projection regeneration GO:0070571 4 0.440
nerve development GO:0021675 45 0.436
cell morphogenesis involved in differentiation GO:0000904 195 0.424
cellular macromolecule metabolic process GO:0044260 391 0.414
auditory receptor cell fate commitment GO:0009912 4 0.413
embryo development ending in birth or egg hatching GO:0009792 271 0.412
neural tube development GO:0021915 62 0.410
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.403
mammillary body development GO:0021767 4 0.402
retina morphogenesis in camera type eye GO:0060042 79 0.401
dopaminergic neuron differentiation GO:0071542 14 0.399
negative regulation of transcription dna templated GO:0045892 45 0.394
olfactory lobe development GO:0021988 4 0.387
regulation of nitrogen compound metabolic process GO:0051171 251 0.383
positive regulation of metabolic process GO:0009893 108 0.383
embryonic organ morphogenesis GO:0048562 274 0.379
cardioblast migration GO:0003260 7 0.375
inner ear development GO:0048839 126 0.371
negative regulation of gliogenesis GO:0014014 1 0.360
brain morphogenesis GO:0048854 18 0.357
forebrain neuron differentiation GO:0021879 14 0.336
negative regulation of cellular biosynthetic process GO:0031327 55 0.325
eye photoreceptor cell development GO:0042462 30 0.318
retina layer formation GO:0010842 24 0.312
neuron projection guidance GO:0097485 86 0.305
artery development GO:0060840 22 0.304
fin morphogenesis GO:0033334 53 0.300
enzyme linked receptor protein signaling pathway GO:0007167 106 0.298
lens development in camera type eye GO:0002088 22 0.294
regulation of multicellular organismal process GO:0051239 277 0.294
reproductive process GO:0022414 40 0.293
determination of bilateral symmetry GO:0009855 204 0.290
ear morphogenesis GO:0042471 64 0.289
inner ear receptor cell fate commitment GO:0060120 4 0.287
retinal cell programmed cell death GO:0046666 2 0.285
cell morphogenesis GO:0000902 289 0.285
gland development GO:0048732 143 0.279
embryonic heart tube morphogenesis GO:0003143 108 0.279
gastrulation GO:0007369 208 0.273
ventral spinal cord interneuron specification GO:0021521 3 0.272
neural tube patterning GO:0021532 33 0.269
specification of symmetry GO:0009799 204 0.268
angiogenesis GO:0001525 158 0.267
negative regulation of cell development GO:0010721 26 0.260
primary neural tube formation GO:0014020 1 0.259
mesenchymal cell development GO:0014031 78 0.252
forebrain dorsal ventral pattern formation GO:0021798 1 0.250
locomotion GO:0040011 313 0.246
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.242
negative regulation of collateral sprouting of intact axon in response to injury GO:0048685 2 0.241
negative regulation of leukocyte differentiation GO:1902106 1 0.238
response to organic substance GO:0010033 153 0.237
single organism metabolic process GO:0044710 217 0.236
regulation of oligodendrocyte differentiation GO:0048713 1 0.232
metencephalon development GO:0022037 27 0.231
diencephalon morphogenesis GO:0048852 5 0.231
regulation of neural precursor cell proliferation GO:2000177 3 0.228
neuroblast proliferation GO:0007405 2 0.227
neuron projection morphogenesis GO:0048812 161 0.226
embryonic eye morphogenesis GO:0048048 30 0.222
determination of heart left right asymmetry GO:0061371 117 0.220
hematopoietic or lymphoid organ development GO:0048534 191 0.220
immune system development GO:0002520 191 0.218
axonogenesis GO:0007409 152 0.214
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.214
negative regulation of macromolecule metabolic process GO:0010605 76 0.213
vasculature development GO:0001944 278 0.211
positive regulation of nervous system development GO:0051962 25 0.209
lens morphogenesis in camera type eye GO:0002089 7 0.207
negative regulation of biological process GO:0048519 304 0.206
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.202
tube morphogenesis GO:0035239 349 0.199
regulation of signal transduction GO:0009966 225 0.196
stem cell maintenance GO:0019827 4 0.193
vasculogenesis GO:0001570 41 0.193
thalamus development GO:0021794 6 0.192
heart morphogenesis GO:0003007 156 0.192
forebrain midbrain boundary formation GO:0021905 1 0.190
olfactory bulb development GO:0021772 4 0.189
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.186
dorsal ventral pattern formation GO:0009953 125 0.185
sexual reproduction GO:0019953 36 0.180
response to abiotic stimulus GO:0009628 122 0.179
positive regulation of jun kinase activity GO:0043507 2 0.179
regulation of cell communication GO:0010646 232 0.179
midbrain hindbrain boundary morphogenesis GO:0021555 5 0.178
oligodendrocyte differentiation GO:0048709 23 0.175
nose development GO:0043584 3 0.174
cell proliferation in hindbrain GO:0021534 4 0.173
mechanoreceptor differentiation GO:0042490 37 0.173
forebrain neuron development GO:0021884 7 0.172
rostrocaudal neural tube patterning GO:0021903 29 0.172
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.171
positive regulation of gene expression GO:0010628 71 0.170
maintenance of location GO:0051235 4 0.169
somitogenesis GO:0001756 87 0.169
neural precursor cell proliferation GO:0061351 20 0.163
endodermal cell differentiation GO:0035987 19 0.163
negative regulation of biosynthetic process GO:0009890 55 0.163
negative regulation of collateral sprouting GO:0048671 2 0.163
body morphogenesis GO:0010171 16 0.160
photoreceptor cell fate commitment GO:0046552 1 0.157
glial cell fate specification GO:0021780 4 0.156
developmental pigmentation GO:0048066 48 0.156
inner ear morphogenesis GO:0042472 63 0.155
kidney development GO:0001822 92 0.154
neural crest cell development GO:0014032 62 0.153
central nervous system myelination GO:0022010 2 0.151
wound healing GO:0042060 90 0.150
neural crest cell migration GO:0001755 42 0.148
embryonic pattern specification GO:0009880 44 0.148
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.148
regeneration GO:0031099 91 0.147
negative regulation of rna metabolic process GO:0051253 48 0.147
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.147
epithelial tube morphogenesis GO:0060562 148 0.146
response to external stimulus GO:0009605 264 0.145
oligodendrocyte cell fate specification GO:0021778 4 0.144
regulation of cell differentiation GO:0045595 142 0.143
endodermal cell fate determination GO:0007493 2 0.143
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.141
positive regulation of multicellular organismal process GO:0051240 52 0.138
cell motility GO:0048870 244 0.138
gamete generation GO:0007276 33 0.136
negative regulation of mitosis GO:0045839 3 0.136
dna methylation on cytosine GO:0032776 3 0.135
synaptic target recognition GO:0008039 1 0.132
telencephalon development GO:0021537 14 0.131
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.131
ectodermal placode formation GO:0060788 26 0.130
forebrain morphogenesis GO:0048853 6 0.130
pons development GO:0021548 11 0.129
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.129
axis elongation involved in somitogenesis GO:0090245 2 0.128
protein import GO:0017038 3 0.127
cellular response to fatty acid GO:0071398 3 0.127
negative chemotaxis GO:0050919 1 0.126
heart development GO:0007507 313 0.126
facial nucleus development GO:0021754 7 0.125
regulation of collateral sprouting of intact axon in response to injury GO:0048683 2 0.124
negative regulation of cellular process GO:0048523 283 0.122
neuron projection development GO:0031175 180 0.122
mesoderm development GO:0007498 88 0.122
abducens nucleus development GO:0021742 2 0.122
embryonic skeletal system development GO:0048706 97 0.122
embryonic camera type eye development GO:0031076 29 0.120
negative regulation of response to stimulus GO:0048585 104 0.118
cerebellum formation GO:0021588 2 0.118
phosphorus metabolic process GO:0006793 109 0.117
stem cell development GO:0048864 82 0.116
multicellular organism growth GO:0035264 4 0.116
regulation of response to stimulus GO:0048583 269 0.115
pituitary gland development GO:0021983 16 0.115
taxis GO:0042330 109 0.115
neuroblast differentiation GO:0014016 1 0.114
lateral line system development GO:0048925 76 0.114
cellular component assembly involved in morphogenesis GO:0010927 107 0.114
lipid storage GO:0019915 1 0.113
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.111
limb bud formation GO:0060174 2 0.110
positive regulation of biosynthetic process GO:0009891 68 0.110
pectoral fin morphogenesis GO:0035138 29 0.109
embryonic organ development GO:0048568 381 0.109
spermatid development GO:0007286 2 0.109
cell part morphogenesis GO:0032990 246 0.108
circadian regulation of gene expression GO:0032922 8 0.108
cell cell recognition GO:0009988 1 0.107
hindbrain development GO:0030902 91 0.107
cilium morphogenesis GO:0060271 85 0.106
cell proliferation in midbrain GO:0033278 4 0.106
peripheral nervous system development GO:0007422 55 0.106
hair cell differentiation GO:0035315 32 0.105
determination of pancreatic left right asymmetry GO:0035469 11 0.105
stem cell differentiation GO:0048863 117 0.104
regulation of neuron differentiation GO:0045664 56 0.104
leukocyte activation GO:0045321 12 0.104
cellular nitrogen compound biosynthetic process GO:0044271 218 0.103
cell cell signaling involved in cell fate commitment GO:0045168 12 0.103
multi organism process GO:0051704 134 0.101
regulation of cell development GO:0060284 100 0.100
striated muscle tissue development GO:0014706 110 0.100
regulation of anatomical structure morphogenesis GO:0022603 130 0.097
otic vesicle morphogenesis GO:0071600 34 0.097
convergent extension GO:0060026 118 0.096
mesoderm morphogenesis GO:0048332 51 0.096
somite specification GO:0001757 12 0.095
negative regulation of multicellular organismal process GO:0051241 69 0.094
tube closure GO:0060606 1 0.094
retina development in camera type eye GO:0060041 146 0.094
positive regulation of neuron migration GO:2001224 2 0.093
odontogenesis of dentin containing tooth GO:0042475 1 0.093
brain segmentation GO:0035284 6 0.091
regulation of glial cell differentiation GO:0045685 4 0.091
regulation of nervous system development GO:0051960 90 0.090
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.090
camera type eye photoreceptor cell differentiation GO:0060219 19 0.090
anterior posterior axis specification GO:0009948 20 0.089
methylation GO:0032259 22 0.088
axon ensheathment in central nervous system GO:0032291 2 0.088
regulation of signaling GO:0023051 235 0.088
developmental process involved in reproduction GO:0003006 27 0.088
transcription from rna polymerase ii promoter GO:0006366 80 0.087
epithelial cell differentiation GO:0030855 116 0.085
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.085
pigmentation GO:0043473 85 0.084
hypothalamus cell differentiation GO:0021979 4 0.083
protein metabolic process GO:0019538 183 0.082
muscle tissue development GO:0060537 110 0.082
embryonic heart tube development GO:0035050 133 0.081
somite development GO:0061053 96 0.080
regulation of developmental process GO:0050793 247 0.080
retinal ganglion cell axon guidance GO:0031290 35 0.079
embryonic camera type eye morphogenesis GO:0048596 19 0.079
retinal pigment epithelium development GO:0003406 8 0.079
axial mesoderm morphogenesis GO:0048319 8 0.078
response to drug GO:0042493 3 0.076
circulatory system process GO:0003013 87 0.075
germ cell development GO:0007281 22 0.075
phosphate containing compound metabolic process GO:0006796 108 0.075
mesenchymal cell differentiation GO:0048762 87 0.074
astrocyte differentiation GO:0048708 1 0.073
renal system development GO:0072001 94 0.072
auditory receptor cell fate determination GO:0042668 2 0.071
radial glial cell differentiation GO:0060019 2 0.071
response to stress GO:0006950 263 0.070
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.070
positive regulation of rna biosynthetic process GO:1902680 57 0.069
meiotic nuclear division GO:0007126 4 0.069
inner ear receptor cell differentiation GO:0060113 29 0.067
dorsal ventral axis specification GO:0009950 14 0.067
development of primary female sexual characteristics GO:0046545 4 0.067
pancreatic a cell development GO:0003322 2 0.067
heart jogging GO:0003146 40 0.067
male meiosis GO:0007140 2 0.065
negative regulation of developmental process GO:0051093 65 0.064
determination of dorsal ventral asymmetry GO:0048262 34 0.063
regulation of cell fate commitment GO:0010453 22 0.063
convergent extension involved in organogenesis GO:0060029 10 0.063
neural plate pattern specification GO:0060896 12 0.063
pharyngeal system development GO:0060037 18 0.062
negative regulation of rna biosynthetic process GO:1902679 45 0.061
regulation of wnt signaling pathway GO:0030111 53 0.061
rhombomere development GO:0021546 19 0.061
negative regulation of cellular metabolic process GO:0031324 77 0.061
positive regulation of stem cell proliferation GO:2000648 1 0.060
circadian rhythm GO:0007623 19 0.059
primitive hemopoiesis GO:0060215 27 0.059
formation of primary germ layer GO:0001704 62 0.059
prechordal plate formation GO:0021501 3 0.059
regulation of gtp catabolic process GO:0033124 2 0.059
axis specification GO:0009798 43 0.059
adenohypophysis development GO:0021984 15 0.058
urogenital system development GO:0001655 97 0.058
negative regulation of signaling GO:0023057 96 0.057
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.056
innervation GO:0060384 3 0.055
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.055
negative regulation of axon regeneration GO:0048681 4 0.055
ion transport GO:0006811 114 0.054
lateral line ganglion development GO:0048890 2 0.054
positive regulation of nucleic acid templated transcription GO:1903508 57 0.054
liver development GO:0001889 96 0.054
positive regulation of cellular process GO:0048522 201 0.054
motor neuron axon guidance GO:0008045 23 0.053
positive regulation of transcription dna templated GO:0045893 57 0.053
tissue regeneration GO:0042246 74 0.053
multi organism reproductive process GO:0044703 36 0.053
regulation of multicellular organism growth GO:0040014 4 0.053
cell fate specification GO:0001708 68 0.051
ventricular system development GO:0021591 12 0.051
cell cycle process GO:0022402 53 0.051
pronephros development GO:0048793 69 0.051
androgen metabolic process GO:0008209 2 0.050
pancreatic d cell differentiation GO:0003311 2 0.050
establishment of protein localization to organelle GO:0072594 4 0.050
protein import into nucleus GO:0006606 3 0.050
negative regulation of neurogenesis GO:0050768 20 0.050
response to amino acid GO:0043200 2 0.050
response to temperature stimulus GO:0009266 15 0.050
epiboly GO:0090504 41 0.049
neural plate anterior posterior regionalization GO:0021999 8 0.049
gliogenesis GO:0042063 45 0.049
midbrain hindbrain boundary development GO:0030917 23 0.049
neural plate regionalization GO:0060897 10 0.049
nuclear transport GO:0051169 4 0.048
endodermal cell fate commitment GO:0001711 18 0.048
regulation of canonical wnt signaling pathway GO:0060828 34 0.048
multicellular organism reproduction GO:0032504 35 0.048
positive regulation of biological process GO:0048518 253 0.048
entrainment of circadian clock by photoperiod GO:0043153 1 0.048
cilium assembly GO:0042384 58 0.047
appendage morphogenesis GO:0035107 56 0.047
response to fibroblast growth factor GO:0071774 22 0.046
sympathetic nervous system development GO:0048485 3 0.046
central nervous system myelin formation GO:0032289 1 0.046
embryonic hemopoiesis GO:0035162 53 0.044
positive regulation of transport GO:0051050 2 0.044
regulation of cell migration GO:0030334 40 0.043
nucleocytoplasmic transport GO:0006913 4 0.043
skeletal system morphogenesis GO:0048705 102 0.043
negative regulation of axon extension GO:0030517 7 0.043
chemotaxis GO:0006935 104 0.043
spermatid differentiation GO:0048515 2 0.043
glial cell differentiation GO:0010001 42 0.043
regulation of collateral sprouting GO:0048670 7 0.042
negative regulation of mapk cascade GO:0043409 4 0.042
establishment of localization GO:0051234 244 0.041
fourth ventricle development GO:0021592 8 0.041
regulation of neuron projection development GO:0010975 40 0.041
female sex differentiation GO:0046660 4 0.041
negative regulation of cell differentiation GO:0045596 46 0.041
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.041
negative regulation of neuron differentiation GO:0045665 10 0.041
regulation of developmental growth GO:0048638 38 0.040
spinal cord patterning GO:0021511 6 0.040
epithelium regeneration GO:1990399 14 0.040
embryonic cranial skeleton morphogenesis GO:0048701 90 0.040
mesodermal cell differentiation GO:0048333 21 0.040
hemopoiesis GO:0030097 183 0.040
adult behavior GO:0030534 2 0.040
cellular response to organic substance GO:0071310 105 0.040
skeletal muscle organ development GO:0060538 78 0.039
segment specification GO:0007379 12 0.039
inner ear receptor cell development GO:0060119 20 0.039
atrioventricular valve formation GO:0003190 3 0.039
specification of organ identity GO:0010092 2 0.039
cartilage development GO:0051216 96 0.039
neuron recognition GO:0008038 18 0.039
neuroepithelial cell differentiation GO:0060563 26 0.039
collateral sprouting of intact axon in response to injury GO:0048673 2 0.039
fin development GO:0033333 77 0.039
mesenchyme development GO:0060485 127 0.038
regulation of intracellular protein transport GO:0033157 3 0.038
septum transversum development GO:0003343 4 0.038
heart valve formation GO:0003188 4 0.038
locus ceruleus development GO:0021703 3 0.038
single organism reproductive process GO:0044702 40 0.037
angioblast cell migration GO:0035476 9 0.037
cell projection morphogenesis GO:0048858 244 0.037
lateral inhibition GO:0046331 1 0.037
response to wounding GO:0009611 116 0.037
pancreas development GO:0031016 84 0.037
cilium organization GO:0044782 71 0.036
gastrulation with mouth forming second GO:0001702 44 0.036
negative regulation of metabolic process GO:0009892 86 0.036
organelle assembly GO:0070925 110 0.036
otic placode formation GO:0043049 23 0.036
appendage development GO:0048736 80 0.036
anatomical structure arrangement GO:0048532 2 0.036
regulation of protein import into nucleus GO:0042306 2 0.036
locomotory behavior GO:0007626 34 0.036
positive regulation of rna metabolic process GO:0051254 59 0.036
optic placode formation GO:0001743 4 0.036
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.036
neuromast development GO:0048884 46 0.035
myeloid cell homeostasis GO:0002262 56 0.035
negative regulation of nervous system development GO:0051961 22 0.034
positive regulation of jnk cascade GO:0046330 3 0.034
ventral spinal cord interneuron fate commitment GO:0060579 3 0.034
negative regulation of wnt signaling pathway GO:0030178 30 0.033
positive regulation of cell development GO:0010720 25 0.033
glial cell development GO:0021782 20 0.033
developmental growth GO:0048589 166 0.033
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.033
macromolecule localization GO:0033036 54 0.033
regulation of stem cell proliferation GO:0072091 2 0.033
organ formation GO:0048645 17 0.033
hepaticobiliary system development GO:0061008 98 0.032
positive regulation of macromolecule metabolic process GO:0010604 93 0.032
melanosome transport GO:0032402 19 0.032
water homeostasis GO:0030104 4 0.032
regulation of purine nucleotide catabolic process GO:0033121 2 0.031
ectodermal placode morphogenesis GO:0071697 32 0.031
organelle localization GO:0051640 49 0.031
iris morphogenesis GO:0061072 1 0.031
multicellular organismal reproductive process GO:0048609 35 0.031
positive regulation of developmental process GO:0051094 50 0.030
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.030
spinal cord oligodendrocyte cell differentiation GO:0021529 5 0.030
embryonic camera type eye formation GO:0060900 10 0.030
aorta morphogenesis GO:0035909 3 0.029
cellular response to prostaglandin stimulus GO:0071379 3 0.029
embryonic limb morphogenesis GO:0030326 2 0.029
negative regulation of epithelial cell proliferation GO:0050680 1 0.029
negative regulation of myeloid leukocyte differentiation GO:0002762 1 0.029
death GO:0016265 121 0.029
muscle structure development GO:0061061 196 0.028
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 6 0.028
cell migration involved in heart formation GO:0060974 10 0.028
regulation of establishment of protein localization GO:0070201 4 0.028
entrainment of circadian clock GO:0009649 2 0.028
leukocyte differentiation GO:0002521 25 0.028
peripheral nervous system neuron development GO:0048935 22 0.028
embryonic pectoral fin morphogenesis GO:0035118 24 0.028
embryonic viscerocranium morphogenesis GO:0048703 52 0.028
neuron migration GO:0001764 22 0.027

otx1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.156
congenital nervous system abnormality DOID:2490 0 0.089
sensory system disease DOID:0050155 0 0.082
disease of anatomical entity DOID:7 0 0.082
eye and adnexa disease DOID:1492 0 0.082
nervous system disease DOID:863 0 0.082