Danio rerio

106 known processes

pard3

par-3 partitioning defective 3 homolog (C. elegans)

(Aliases: par3,par-3,bazooka,asip)

pard3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of neurotransmitter transport GO:0051588 1 0.313
cognition GO:0050890 1 0.208
signal transduction GO:0007165 455 0.182
embryonic organ development GO:0048568 381 0.179
morphogenesis of an epithelium GO:0002009 333 0.173
regulation of synapse organization GO:0050807 3 0.166
sensory organ development GO:0007423 393 0.164
negative regulation of cell communication GO:0010648 96 0.149
negative regulation of response to stimulus GO:0048585 104 0.142
embryonic heart tube development GO:0035050 133 0.134
neuron differentiation GO:0030182 353 0.132
digestive tract morphogenesis GO:0048546 231 0.120
camera type eye morphogenesis GO:0048593 108 0.120
neurotransmitter secretion GO:0007269 2 0.118
tube morphogenesis GO:0035239 349 0.116
organelle organization GO:0006996 227 0.110
regulation of cellular metabolic process GO:0031323 320 0.105
epithelial tube morphogenesis GO:0060562 148 0.103
neurotransmitter transport GO:0006836 2 0.102
camera type eye development GO:0043010 222 0.102
regulation of signaling GO:0023051 235 0.099
regulation of cell differentiation GO:0045595 142 0.098
cellular component movement GO:0006928 335 0.096
regionalization GO:0003002 274 0.095
heart development GO:0007507 313 0.094
regulation of synapse assembly GO:0051963 3 0.088
retina development in camera type eye GO:0060041 146 0.088
positive regulation of cellular component biogenesis GO:0044089 3 0.087
eye morphogenesis GO:0048592 144 0.086
regulation of signal transduction GO:0009966 225 0.085
cell death GO:0008219 121 0.084
hematopoietic or lymphoid organ development GO:0048534 191 0.080
positive regulation of synapse assembly GO:0051965 1 0.077
embryonic organ morphogenesis GO:0048562 274 0.073
regulation of apoptotic process GO:0042981 98 0.072
retina layer formation GO:0010842 24 0.070
cellular component assembly GO:0022607 170 0.069
Rat
ameboidal type cell migration GO:0001667 143 0.067
regulation of macromolecule biosynthetic process GO:0010556 225 0.067
nucleobase containing compound metabolic process GO:0006139 274 0.067
localization of cell GO:0051674 244 0.066
digestive tract mesoderm development GO:0007502 1 0.065
organonitrogen compound metabolic process GO:1901564 74 0.064
determination of left right symmetry GO:0007368 179 0.064
regulation of neurotransmitter secretion GO:0046928 1 0.064
cell projection morphogenesis GO:0048858 244 0.062
lateral inhibition GO:0046331 1 0.061
embryonic heart tube morphogenesis GO:0003143 108 0.059
retina morphogenesis in camera type eye GO:0060042 79 0.059
regulation of primary metabolic process GO:0080090 311 0.059
cellular amine metabolic process GO:0044106 2 0.057
eye development GO:0001654 277 0.057
angiogenesis GO:0001525 158 0.056
phosphate containing compound metabolic process GO:0006796 108 0.055
negative regulation of biological process GO:0048519 304 0.053
organic cyclic compound metabolic process GO:1901360 301 0.053
larval development GO:0002164 2 0.052
cell part morphogenesis GO:0032990 246 0.052
developmental growth GO:0048589 166 0.051
negative regulation of signaling GO:0023057 96 0.050
blood vessel morphogenesis GO:0048514 216 0.049
sensory organ morphogenesis GO:0090596 200 0.049
autophagy GO:0006914 4 0.049
developmental cell growth GO:0048588 52 0.049
determination of bilateral symmetry GO:0009855 204 0.049
negative regulation of signal transduction GO:0009968 94 0.048
regulation of cellular response to oxidative stress GO:1900407 2 0.048
nitrogen compound metabolic process GO:0006807 319 0.048
regulation of multicellular organismal process GO:0051239 277 0.048
digestive tract development GO:0048565 265 0.047
establishment of localization GO:0051234 244 0.047
cilium organization GO:0044782 71 0.046
neuron development GO:0048666 262 0.046
cell surface receptor signaling pathway GO:0007166 325 0.045
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.045
positive regulation of secretion GO:0051047 1 0.045
regulation of response to stimulus GO:0048583 269 0.045
sprouting angiogenesis GO:0002040 53 0.044
cellular component biogenesis GO:0044085 178 0.043
Rat
cellular nitrogen compound metabolic process GO:0034641 290 0.043
regulation of gene expression GO:0010468 265 0.043
cell migration GO:0016477 237 0.043
photoreceptor cell differentiation GO:0046530 55 0.042
single organism organelle organization GO:1902589 199 0.042
regulation of protein complex assembly GO:0043254 3 0.042
regulation of cell death GO:0010941 103 0.042
heart morphogenesis GO:0003007 156 0.041
generation of neurons GO:0048699 385 0.041
regulation of metabolic process GO:0019222 359 0.041
nucleic acid metabolic process GO:0090304 244 0.041
heterocycle metabolic process GO:0046483 290 0.040
cellular macromolecule metabolic process GO:0044260 391 0.040
gastrulation GO:0007369 208 0.040
apoptotic process GO:0006915 116 0.040
rna metabolic process GO:0016070 219 0.040
regulation of developmental process GO:0050793 247 0.039
odontogenesis of dentin containing tooth GO:0042475 1 0.039
negative regulation of protein phosphorylation GO:0001933 4 0.038
regulation of programmed cell death GO:0043067 101 0.038
positive regulation of secretion by cell GO:1903532 1 0.036
digestive system development GO:0055123 289 0.036
phosphorus metabolic process GO:0006793 109 0.036
cell morphogenesis GO:0000902 289 0.036
regulation of biological quality GO:0065008 263 0.035
regulation of multicellular organism growth GO:0040014 4 0.035
phagocytosis GO:0006909 3 0.035
hemopoiesis GO:0030097 183 0.035
programmed cell death GO:0012501 119 0.035
response to organic substance GO:0010033 153 0.034
mitochondrion organization GO:0007005 4 0.034
system process GO:0003008 185 0.034
regulation of nucleic acid templated transcription GO:1903506 213 0.034
cell junction maintenance GO:0034331 2 0.034
positive regulation of transport GO:0051050 2 0.034
central nervous system development GO:0007417 387 0.034
regulation of oxidative stress induced cell death GO:1903201 2 0.034
specification of symmetry GO:0009799 204 0.033
negative regulation of apoptotic process GO:0043066 55 0.033
death GO:0016265 121 0.033
small molecule metabolic process GO:0044281 77 0.032
regulation of macromolecule metabolic process GO:0060255 317 0.032
single organism localization GO:1902578 225 0.032
Rat
regulation of nitrogen compound metabolic process GO:0051171 251 0.032
aging GO:0007568 2 0.031
nucleobase containing compound biosynthetic process GO:0034654 205 0.031
response to drug GO:0042493 3 0.031
single organism transport GO:0044765 206 0.031
Rat
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.030
regulation of intracellular signal transduction GO:1902531 57 0.030
amine metabolic process GO:0009308 2 0.030
regulation of protein transport GO:0051223 3 0.030
aromatic compound biosynthetic process GO:0019438 217 0.030
neuron projection morphogenesis GO:0048812 161 0.029
transcription dna templated GO:0006351 181 0.029
cell matrix adhesion GO:0007160 4 0.029
developmental growth involved in morphogenesis GO:0060560 86 0.029
immune system process GO:0002376 241 0.029
blood circulation GO:0008015 87 0.029
actin filament based movement GO:0030048 1 0.028
intracellular signal transduction GO:0035556 85 0.028
positive regulation of developmental process GO:0051094 50 0.028
gene expression GO:0010467 252 0.028
regulation of cytokine production GO:0001817 3 0.028
cell cell signaling GO:0007267 52 0.028
regulation of cell activation GO:0050865 1 0.028
negative regulation of cellular process GO:0048523 283 0.028
gtp metabolic process GO:0046039 4 0.028
medulla oblongata development GO:0021550 4 0.028
regulation of nucleoside metabolic process GO:0009118 2 0.028
cellular response to extracellular stimulus GO:0031668 2 0.028
cellular response to organic substance GO:0071310 105 0.027
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.027
response to nutrient GO:0007584 3 0.027
guanosine containing compound metabolic process GO:1901068 4 0.027
single organism metabolic process GO:0044710 217 0.027
negative regulation of protein complex assembly GO:0031333 1 0.027
regulation of rna biosynthetic process GO:2001141 213 0.027
adherens junction organization GO:0034332 4 0.027
cellular response to chemical stimulus GO:0070887 157 0.026
cellular component morphogenesis GO:0032989 336 0.026
ovulation cycle GO:0042698 2 0.026
cell projection organization GO:0030030 284 0.026
determination of heart left right asymmetry GO:0061371 117 0.026
organic substance biosynthetic process GO:1901576 289 0.026
response to vitamin GO:0033273 3 0.026
extrinsic apoptotic signaling pathway GO:0097191 3 0.026
kidney development GO:0001822 92 0.025
protein localization to plasma membrane GO:0072659 1 0.025
apoptotic process involved in development GO:1902742 2 0.025
regulation of nucleotide catabolic process GO:0030811 2 0.025
protein complex disassembly GO:0043241 1 0.025
developmental programmed cell death GO:0010623 4 0.025
nucleocytoplasmic transport GO:0006913 4 0.024
gtp catabolic process GO:0006184 2 0.024
neurological system process GO:0050877 62 0.024
skeletal system development GO:0001501 181 0.024
cellular response to nutrient levels GO:0031669 2 0.024
polarized epithelial cell differentiation GO:0030859 4 0.023
rna biosynthetic process GO:0032774 181 0.023
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.023
response to monosaccharide GO:0034284 3 0.023
guanosine containing compound catabolic process GO:1901069 2 0.023
cell adhesion GO:0007155 40 0.022
heart looping GO:0001947 94 0.022
regulation of cellular ketone metabolic process GO:0010565 7 0.022
response to chemical GO:0042221 320 0.022
regulation of mrna catabolic process GO:0061013 3 0.022
cellular response to external stimulus GO:0071496 2 0.022
positive regulation of multicellular organismal process GO:0051240 52 0.022
cellular nitrogen compound biosynthetic process GO:0044271 218 0.022
regulation of muscle contraction GO:0006937 3 0.022
multicellular organism growth GO:0035264 4 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
embryonic hemopoiesis GO:0035162 53 0.021
response to carbohydrate GO:0009743 3 0.021
vasculature development GO:0001944 278 0.021
protein metabolic process GO:0019538 183 0.021
cellular biosynthetic process GO:0044249 286 0.021
negative regulation of programmed cell death GO:0043069 58 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
cell growth GO:0016049 57 0.021
multicellular organismal signaling GO:0035637 22 0.021
cilium assembly GO:0042384 58 0.021
regulation of rna metabolic process GO:0051252 224 0.021
heart process GO:0003015 71 0.020
secondary metabolic process GO:0019748 3 0.020
neuroblast proliferation GO:0007405 2 0.020
response to organic cyclic compound GO:0014070 51 0.020
establishment of monopolar cell polarity GO:0061162 2 0.020
blood vessel development GO:0001568 246 0.020
mesoderm development GO:0007498 88 0.020
regulation of localization GO:0032879 104 0.020
Rat
response to alkaloid GO:0043279 2 0.020
positive regulation of cell adhesion GO:0045785 1 0.020
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.020
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.020
macromolecular complex subunit organization GO:0043933 74 0.020
lipid storage GO:0019915 1 0.019
regulation of organ morphogenesis GO:2000027 35 0.019
immune system development GO:0002520 191 0.019
endothelial cell migration GO:0043542 19 0.019
single organism membrane organization GO:0044802 20 0.019
Rat
negative regulation of intracellular signal transduction GO:1902532 22 0.019
regulation of synaptic plasticity GO:0048167 1 0.019
cellular response to starvation GO:0009267 1 0.019
maintenance of location GO:0051235 4 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.019
regulation of cellular biosynthetic process GO:0031326 245 0.019
photoreceptor cell outer segment organization GO:0035845 9 0.019
regulation of cell shape GO:0008360 1 0.019
regulation of gtp catabolic process GO:0033124 2 0.018
response to corticosteroid GO:0031960 1 0.018
negative regulation of secretion GO:0051048 2 0.018
regulation of protein polymerization GO:0032271 2 0.018
protein polymerization GO:0051258 4 0.018
circulatory system process GO:0003013 87 0.018
positive regulation of nucleotide catabolic process GO:0030813 1 0.018
centrosome organization GO:0051297 1 0.018
skeletal system morphogenesis GO:0048705 102 0.018
cellular response to hormone stimulus GO:0032870 39 0.018
cell morphogenesis involved in differentiation GO:0000904 195 0.018
monoamine transport GO:0015844 1 0.018
regulation of cell development GO:0060284 100 0.018
synaptic growth at neuromuscular junction GO:0051124 2 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
neuromuscular process controlling balance GO:0050885 3 0.018
stem cell proliferation GO:0072089 4 0.017
negative regulation of cellular metabolic process GO:0031324 77 0.017
response to hexose GO:0009746 3 0.017
neuromuscular synaptic transmission GO:0007274 2 0.017
regulation of mrna processing GO:0050684 3 0.017
chordate embryonic development GO:0043009 271 0.017
regulation of molecular function GO:0065009 70 0.017
protein secretion GO:0009306 1 0.017
regulation of cell motility GO:2000145 46 0.017
production of molecular mediator of immune response GO:0002440 2 0.017
rna processing GO:0006396 25 0.016
positive regulation of cell substrate adhesion GO:0010811 1 0.016
regulation of phosphate metabolic process GO:0019220 43 0.016
actin filament polymerization GO:0030041 2 0.016
actin cytoskeleton organization GO:0030036 63 0.016
synaptic transmission GO:0007268 35 0.016
cell substrate adhesion GO:0031589 4 0.016
positive regulation of gtp catabolic process GO:0033126 1 0.016
nuclear transport GO:0051169 4 0.016
positive regulation of response to stimulus GO:0048584 80 0.016
heart contraction GO:0060047 71 0.016
organic cyclic compound biosynthetic process GO:1901362 223 0.016
tube closure GO:0060606 1 0.016
response to glucocorticoid GO:0051384 1 0.016
response to wounding GO:0009611 116 0.016
regulation of phospholipase activity GO:0010517 2 0.016
nuclear transcribed mrna catabolic process GO:0000956 4 0.016
cellular aromatic compound metabolic process GO:0006725 295 0.015
regulation of biosynthetic process GO:0009889 250 0.015
regulation of response to cytokine stimulus GO:0060759 3 0.015
gland development GO:0048732 143 0.015
regulation of binding GO:0051098 3 0.015
embryonic cranial skeleton morphogenesis GO:0048701 90 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
sensory perception of light stimulus GO:0050953 19 0.015
somatic stem cell maintenance GO:0035019 1 0.015
regulation of gtpase activity GO:0043087 2 0.015
actin filament based process GO:0030029 64 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 9 0.015
cytoskeleton organization GO:0007010 96 0.015
nephron morphogenesis GO:0072028 2 0.015
lamellipodium organization GO:0097581 1 0.015
positive regulation of gtpase activity GO:0043547 1 0.015
primary neural tube formation GO:0014020 1 0.015
morphogenesis of embryonic epithelium GO:0016331 30 0.015
renal system development GO:0072001 94 0.015
regulation of cell communication GO:0010646 232 0.015
peptidyl serine phosphorylation GO:0018105 1 0.015
glucose import GO:0046323 2 0.015
regulation of axonogenesis GO:0050770 32 0.015
protein localization to nucleus GO:0034504 3 0.014
positive regulation of catabolic process GO:0009896 4 0.014
muscle cell development GO:0055001 115 0.014
axonogenesis GO:0007409 152 0.014
cellular component maintenance GO:0043954 3 0.014
carboxylic acid metabolic process GO:0019752 22 0.014
positive regulation of immune effector process GO:0002699 3 0.014
positive regulation of biological process GO:0048518 253 0.014
post embryonic organ development GO:0048569 4 0.014
cellular component disassembly GO:0022411 1 0.014
regulation of intracellular protein transport GO:0033157 3 0.014
nerve development GO:0021675 45 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
regulation of protein catabolic process GO:0042176 1 0.014
cell death in response to oxidative stress GO:0036473 2 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.014
regulation of protein binding GO:0043393 3 0.014
microtubule organizing center organization GO:0031023 1 0.014
growth GO:0040007 174 0.014
rna 3 end processing GO:0031123 2 0.014
organelle assembly GO:0070925 110 0.014
negative regulation of gene expression GO:0010629 65 0.014
response to ketone GO:1901654 1 0.014
pronephros development GO:0048793 69 0.013
peptidyl serine modification GO:0018209 2 0.013
positive regulation of cytokine production GO:0001819 2 0.013
macromolecule modification GO:0043412 111 0.013
regulation of neural precursor cell proliferation GO:2000177 3 0.013
regulation of cytoplasmic transport GO:1903649 4 0.013
regulation of jak stat cascade GO:0046425 3 0.013
cellular localization GO:0051641 97 0.013
regulation of striated muscle contraction GO:0006942 2 0.013
urogenital system development GO:0001655 97 0.013
biosynthetic process GO:0009058 294 0.013
regulation of metal ion transport GO:0010959 4 0.013
toll like receptor signaling pathway GO:0002224 4 0.013
embryo development ending in birth or egg hatching GO:0009792 271 0.013
heterocycle biosynthetic process GO:0018130 215 0.013
cellular ketone metabolic process GO:0042180 11 0.013
organic acid metabolic process GO:0006082 31 0.013
microtubule based process GO:0007017 60 0.013
macromolecular complex disassembly GO:0032984 1 0.013
establishment of epithelial cell polarity GO:0090162 2 0.013
Rat
organic substance transport GO:0071702 58 0.013
Rat
axon development GO:0061564 166 0.013
regulation of phosphorus metabolic process GO:0051174 43 0.013
stem cell maintenance GO:0019827 4 0.013
oxoacid metabolic process GO:0043436 31 0.013
protein heterooligomerization GO:0051291 1 0.013
regulation of vasculature development GO:1901342 33 0.013
regulation of stem cell proliferation GO:0072091 2 0.013
embryonic skeletal system morphogenesis GO:0048704 93 0.013
mrna 3 end processing GO:0031124 2 0.013
development of primary female sexual characteristics GO:0046545 4 0.013
mitotic dna damage checkpoint GO:0044773 4 0.013
exocytosis GO:0006887 1 0.013
regulation of reproductive process GO:2000241 4 0.012
multi organism cellular process GO:0044764 2 0.012
chemotaxis GO:0006935 104 0.012
positive regulation of protein complex assembly GO:0031334 2 0.012
negative regulation of catalytic activity GO:0043086 21 0.012
central nervous system neuron development GO:0021954 29 0.012
macroautophagy GO:0016236 1 0.012
regulation of postsynaptic membrane potential GO:0060078 1 0.012
response to hormone GO:0009725 48 0.012
actin filament organization GO:0007015 15 0.012
regulation of response to stress GO:0080134 36 0.012
visual perception GO:0007601 17 0.012
rna localization GO:0006403 4 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
glucose homeostasis GO:0042593 1 0.012
hindbrain development GO:0030902 91 0.012
membrane invagination GO:0010324 1 0.012
cellular protein metabolic process GO:0044267 129 0.012
single organism nuclear import GO:1902593 3 0.012
single organismal cell cell adhesion GO:0016337 29 0.012
cell projection assembly GO:0030031 64 0.012
interspecies interaction between organisms GO:0044419 4 0.012
negative regulation of catabolic process GO:0009895 3 0.011
head development GO:0060322 303 0.011
female sex differentiation GO:0046660 4 0.011
cilium morphogenesis GO:0060271 85 0.011
optokinetic behavior GO:0007634 9 0.011
regulation of stem cell differentiation GO:2000736 4 0.011
regulation of catalytic activity GO:0050790 55 0.011
behavior GO:0007610 74 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.011
locomotion GO:0040011 313 0.011
negative regulation of cell differentiation GO:0045596 46 0.011
nephron tubule morphogenesis GO:0072078 1 0.011
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.011
negative regulation of protein transport GO:0051224 3 0.011
cardiac atrium development GO:0003230 4 0.011
negative regulation of oxidative stress induced cell death GO:1903202 2 0.011
actin mediated cell contraction GO:0070252 1 0.011
response to oxygen containing compound GO:1901700 55 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
regulation of response to oxidative stress GO:1902882 2 0.011
cellular protein catabolic process GO:0044257 4 0.011
sensory system development GO:0048880 76 0.011
forebrain cell migration GO:0021885 1 0.011
ovulation cycle process GO:0022602 2 0.011
response to oxidative stress GO:0006979 11 0.011
biological adhesion GO:0022610 40 0.011
centrosome cycle GO:0007098 1 0.011
protein phosphorylation GO:0006468 47 0.011
regulation of system process GO:0044057 40 0.011
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.011
protein modification process GO:0036211 100 0.011
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 11 0.011
chemosensory behavior GO:0007635 1 0.010
positive regulation of leukocyte differentiation GO:1902107 1 0.010
mrna metabolic process GO:0016071 20 0.010
neural crest cell migration GO:0001755 42 0.010
adult behavior GO:0030534 2 0.010
photoreceptor cell development GO:0042461 40 0.010
epithelium migration GO:0090132 25 0.010
desmosome organization GO:0002934 3 0.010
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.010
peptidyl threonine phosphorylation GO:0018107 1 0.010
regulation of erk1 and erk2 cascade GO:0070372 4 0.010
rho protein signal transduction GO:0007266 5 0.010
regulation of inflammatory response GO:0050727 2 0.010
regulation of transmembrane transporter activity GO:0022898 2 0.010
negative regulation of cell death GO:0060548 60 0.010
regulation of neuronal synaptic plasticity GO:0048168 1 0.010
negative regulation of multi organism process GO:0043901 3 0.010
peptide transport GO:0015833 1 0.010
regulation of transporter activity GO:0032409 2 0.010
amino acid transport GO:0006865 2 0.010
response to glucose GO:0009749 3 0.010

pard3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.077
nervous system disease DOID:863 0 0.029
cardiovascular system disease DOID:1287 0 0.026
musculoskeletal system disease DOID:17 0 0.025
myopathy DOID:423 0 0.019
muscle tissue disease DOID:66 0 0.019
muscular disease DOID:0080000 0 0.019
disease of metabolism DOID:0014667 0 0.016
heart disease DOID:114 0 0.014
cardiomyopathy DOID:0050700 0 0.014
inherited metabolic disorder DOID:655 0 0.014
disease of cellular proliferation DOID:14566 0 0.011