Danio rerio

11 known processes

pax2b

paired box gene 2b

(Aliases: pax2.2)

pax2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.689
Fly
cellular component morphogenesis GO:0032989 336 0.668
Mouse Fly
cell morphogenesis GO:0000902 289 0.664
Mouse Fly
regionalization GO:0003002 274 0.663
Zebrafish Mouse
chemotaxis GO:0006935 104 0.657
response to external stimulus GO:0009605 264 0.582
Zebrafish Mouse
hair cell differentiation GO:0035315 32 0.496
Zebrafish
brain development GO:0007420 293 0.463
Zebrafish Mouse
neuron differentiation GO:0030182 353 0.447
Zebrafish Fly
axon development GO:0061564 166 0.413
cerebellum formation GO:0021588 2 0.404
Zebrafish
cell morphogenesis involved in differentiation GO:0000904 195 0.361
Mouse Fly
generation of neurons GO:0048699 385 0.357
Zebrafish Fly
neural tube development GO:0021915 62 0.338
Zebrafish Mouse
tube morphogenesis GO:0035239 349 0.335
Human Mouse
hindbrain formation GO:0021576 3 0.331
Zebrafish
sensory organ development GO:0007423 393 0.322
Zebrafish Mouse Fly
epidermal cell differentiation GO:0009913 36 0.316
Zebrafish
neuron development GO:0048666 262 0.316
Zebrafish Fly
heterocycle metabolic process GO:0046483 290 0.309
Human Mouse Worm Fly
nitrogen compound metabolic process GO:0006807 319 0.299
Human Mouse Worm Fly
embryonic limb morphogenesis GO:0030326 2 0.294
cell projection organization GO:0030030 284 0.288
Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.278
Human Mouse Worm Fly
transcription from rna polymerase ii promoter GO:0006366 80 0.277
Human Mouse Worm Fly
apoptotic process involved in development GO:1902742 2 0.275
Mouse
regulation of metabolic process GO:0019222 359 0.274
Human Mouse Worm Fly
apoptotic process involved in morphogenesis GO:0060561 2 0.271
Mouse
cell projection morphogenesis GO:0048858 244 0.261
Fly
regulation of neural retina development GO:0061074 2 0.257
Fly
epidermis development GO:0008544 48 0.240
Zebrafish
determination of bilateral symmetry GO:0009855 204 0.240
retina development in camera type eye GO:0060041 146 0.233
Mouse Fly
dorsal ventral pattern formation GO:0009953 125 0.230
regulation of rna metabolic process GO:0051252 224 0.226
Human Mouse Worm Fly
taxis GO:0042330 109 0.219
embryo development ending in birth or egg hatching GO:0009792 271 0.218
Zebrafish Mouse Worm
neural tube patterning GO:0021532 33 0.216
Zebrafish
regulation of macromolecule metabolic process GO:0060255 317 0.212
Human Mouse Worm Fly
chordate embryonic development GO:0043009 271 0.211
Zebrafish Mouse
rostrocaudal neural tube patterning GO:0021903 29 0.208
Zebrafish
regulation of gene expression GO:0010468 265 0.208
Human Mouse Worm Fly
developmental programmed cell death GO:0010623 4 0.205
Mouse
neuron projection morphogenesis GO:0048812 161 0.198
Fly
regulation of retina development in camera type eye GO:1902866 2 0.190
Fly
negative regulation of cellular process GO:0048523 283 0.183
Human Mouse
cell surface receptor signaling pathway GO:0007166 325 0.183
neuron projection guidance GO:0097485 86 0.177
positive regulation of cellular process GO:0048522 201 0.176
Human Mouse Worm Fly
axon guidance GO:0007411 86 0.174
transcription dna templated GO:0006351 181 0.173
Human Mouse Worm Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.166
Human Mouse Worm Fly
regulation of transcription dna templated GO:0006355 213 0.165
Human Mouse Worm Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.163
Human Mouse Worm Fly
locomotion GO:0040011 313 0.160
cell part morphogenesis GO:0032990 246 0.154
Fly
midbrain development GO:0030901 28 0.147
Zebrafish
glial cell migration GO:0008347 3 0.145
cell fate commitment GO:0045165 99 0.143
Zebrafish Mouse Worm Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.141
Human Mouse Worm Fly
regulation of biosynthetic process GO:0009889 250 0.139
Human Mouse Worm Fly
specification of symmetry GO:0009799 204 0.132
regulation of cellular metabolic process GO:0031323 320 0.131
Human Mouse Worm Fly
regulation of response to stimulus GO:0048583 269 0.129
cellular macromolecule metabolic process GO:0044260 391 0.126
Human Mouse Worm Fly
cell fate specification GO:0001708 68 0.123
Zebrafish Mouse Worm Fly
response to chemical GO:0042221 320 0.122
Mouse
nucleic acid templated transcription GO:0097659 181 0.120
Human Mouse Worm Fly
skin development GO:0043588 54 0.113
Zebrafish
synaptic growth at neuromuscular junction GO:0051124 2 0.113
rna metabolic process GO:0016070 219 0.112
Human Mouse Worm Fly
epithelial cell differentiation GO:0030855 116 0.111
Zebrafish Mouse
positive regulation of gene expression GO:0010628 71 0.108
Human Mouse Worm Fly
stem cell development GO:0048864 82 0.108
Mouse
gastrulation GO:0007369 208 0.107
Mouse
digestive system development GO:0055123 289 0.107
Mouse
central nervous system development GO:0007417 387 0.106
Zebrafish Mouse
nucleic acid metabolic process GO:0090304 244 0.105
Human Mouse Worm Fly
regulation of primary metabolic process GO:0080090 311 0.104
Human Mouse Worm Fly
axonogenesis GO:0007409 152 0.103
regulation of rna biosynthetic process GO:2001141 213 0.102
Human Mouse Worm Fly
regulation of multicellular organismal process GO:0051239 277 0.099
Mouse Fly
signal transduction GO:0007165 455 0.098
Mouse
appendage development GO:0048736 80 0.097
gene expression GO:0010467 252 0.095
Human Mouse Worm Fly
regulation of cell communication GO:0010646 232 0.092
morphogenesis of an epithelium GO:0002009 333 0.090
Human Zebrafish Mouse
ear development GO:0043583 127 0.090
Zebrafish Mouse
organic cyclic compound metabolic process GO:1901360 301 0.088
Human Mouse Worm Fly
aromatic compound biosynthetic process GO:0019438 217 0.084
Human Mouse Worm Fly
positive regulation of biological process GO:0048518 253 0.081
Human Mouse Worm Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.081
Human Mouse Worm Fly
motor neuron axon guidance GO:0008045 23 0.079
midbrain hindbrain boundary development GO:0030917 23 0.075
Zebrafish
regulation of endodermal cell fate specification GO:0042663 15 0.074
kidney development GO:0001822 92 0.074
Human Zebrafish Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.073
Human Mouse Worm Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.071
Human Mouse Worm Fly
neuron fate commitment GO:0048663 26 0.071
Fly
regulation of endodermal cell differentiation GO:1903224 15 0.070
rna biosynthetic process GO:0032774 181 0.069
Human Mouse Worm Fly
neuron projection development GO:0031175 180 0.068
Fly
pronephric glomerulus morphogenesis GO:0035775 6 0.068
Zebrafish
reflex GO:0060004 2 0.067
Zebrafish
stem cell maintenance GO:0019827 4 0.067
Mouse
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.066
regulation of multicellular organismal development GO:2000026 223 0.064
Mouse Fly
inner ear receptor cell development GO:0060119 20 0.064
Zebrafish
regulation of developmental process GO:0050793 247 0.064
Mouse Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.062
Human Mouse Worm Fly
multicellular organism growth GO:0035264 4 0.061
regulation of nervous system development GO:0051960 90 0.061
Mouse Fly
epithelial tube morphogenesis GO:0060562 148 0.059
Human Mouse
cell motility GO:0048870 244 0.057
sensory organ morphogenesis GO:0090596 200 0.057
Zebrafish Mouse Fly
regulation of signal transduction GO:0009966 225 0.055
defense response to fungus GO:0050832 2 0.054
inner ear morphogenesis GO:0042472 63 0.053
Zebrafish Mouse
embryonic organ development GO:0048568 381 0.053
Zebrafish Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.053
Human Mouse Worm Fly
positive regulation of metabolic process GO:0009893 108 0.052
Human Mouse Worm Fly
regulation of signaling GO:0023051 235 0.052
regulation of synapse organization GO:0050807 3 0.052
heterocycle biosynthetic process GO:0018130 215 0.051
Human Mouse Worm Fly
digestive tract development GO:0048565 265 0.051
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.051
Human Mouse Worm Fly
nucleobase containing compound metabolic process GO:0006139 274 0.051
Human Mouse Worm Fly
digestive tract morphogenesis GO:0048546 231 0.050
Mouse
regulation of neurogenesis GO:0050767 87 0.049
Fly
cellular component assembly involved in morphogenesis GO:0010927 107 0.048
regulation of photoreceptor cell differentiation GO:0046532 2 0.048
Fly
macromolecule biosynthetic process GO:0009059 227 0.048
Human Mouse Worm Fly
bmp signaling pathway GO:0030509 52 0.048
midbrain hindbrain boundary morphogenesis GO:0021555 5 0.047
negative regulation of biological process GO:0048519 304 0.047
Human Mouse
auditory receptor cell fate commitment GO:0009912 4 0.047
regulation of cell development GO:0060284 100 0.047
Mouse Fly
central nervous system neuron development GO:0021954 29 0.046
positive regulation of embryonic development GO:0040019 3 0.046
pronephros development GO:0048793 69 0.045
Zebrafish Mouse
apoptotic process GO:0006915 116 0.045
Human Mouse
developmental growth involved in morphogenesis GO:0060560 86 0.045
embryonic organ morphogenesis GO:0048562 274 0.044
Zebrafish Mouse
compound eye development GO:0048749 2 0.044
Fly
post embryonic morphogenesis GO:0009886 4 0.044
cellular macromolecule biosynthetic process GO:0034645 224 0.044
Human Mouse Worm Fly
epidermal cell fate specification GO:0009957 4 0.044
pigmentation GO:0043473 85 0.044
biosynthetic process GO:0009058 294 0.044
Human Mouse Worm Fly
cell death GO:0008219 121 0.042
Human Mouse
auditory receptor cell development GO:0060117 8 0.042
head development GO:0060322 303 0.041
Zebrafish Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.041
regulation of neuron differentiation GO:0045664 56 0.040
Fly
enzyme linked receptor protein signaling pathway GO:0007167 106 0.040
regulation of cell shape GO:0008360 1 0.040
pectoral fin development GO:0033339 50 0.039
skeletal system development GO:0001501 181 0.039
positive regulation of cellular metabolic process GO:0031325 94 0.039
Human Mouse Worm Fly
appendage morphogenesis GO:0035107 56 0.039
regulation of protein complex assembly GO:0043254 3 0.039
development of primary female sexual characteristics GO:0046545 4 0.039
auditory receptor cell differentiation GO:0042491 15 0.038
peripheral nervous system development GO:0007422 55 0.038
positive regulation of multicellular organismal process GO:0051240 52 0.038
Mouse
regulation of cell differentiation GO:0045595 142 0.037
Mouse Fly
determination of left right symmetry GO:0007368 179 0.037
urogenital system development GO:0001655 97 0.037
Human Zebrafish Mouse
developmental growth GO:0048589 166 0.036
forebrain regionalization GO:0021871 4 0.036
cognition GO:0050890 1 0.036
lateral line development GO:0048882 66 0.036
female sex differentiation GO:0046660 4 0.036
larval development GO:0002164 2 0.036
Worm
developmental pigmentation GO:0048066 48 0.036
regulation of anatomical structure morphogenesis GO:0022603 130 0.035
Mouse Fly
localization of cell GO:0051674 244 0.035
synaptic target recognition GO:0008039 1 0.035
ear morphogenesis GO:0042471 64 0.035
Zebrafish Mouse
determination of heart left right asymmetry GO:0061371 117 0.035
response to external biotic stimulus GO:0043207 97 0.035
pronephric glomerulus development GO:0039021 13 0.035
Zebrafish
positive regulation of biosynthetic process GO:0009891 68 0.034
Human Mouse Worm Fly
eye morphogenesis GO:0048592 144 0.034
Zebrafish Mouse Fly
negative regulation of endodermal cell differentiation GO:1903225 8 0.034
regulation of cell fate specification GO:0042659 20 0.034
Fly
positive regulation of epithelial cell differentiation GO:0030858 2 0.034
Mouse
single organism membrane fusion GO:0044801 2 0.034
cell migration GO:0016477 237 0.033
regulation of cell death GO:0010941 103 0.033
Human Mouse
stem cell fate determination GO:0048867 1 0.033
germ line stem cell maintenance GO:0030718 2 0.032
ectodermal placode development GO:0071696 37 0.032
Zebrafish
positive regulation of cellular biosynthetic process GO:0031328 68 0.032
Human Mouse Worm Fly
neuron fate determination GO:0048664 2 0.032
regulation of apoptotic process GO:0042981 98 0.032
Human Mouse
central nervous system projection neuron axonogenesis GO:0021952 15 0.032
organic cyclic compound biosynthetic process GO:1901362 223 0.031
Human Mouse Worm Fly
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.031
defense response to other organism GO:0098542 33 0.031
neuroblast differentiation GO:0014016 1 0.031
stem cell differentiation GO:0048863 117 0.030
Mouse
renal system development GO:0072001 94 0.030
Human Zebrafish Mouse
mechanoreceptor differentiation GO:0042490 37 0.030
Zebrafish
cellular response to biotic stimulus GO:0071216 3 0.030
cellular nitrogen compound biosynthetic process GO:0044271 218 0.030
Human Mouse Worm Fly
response to monosaccharide GO:0034284 3 0.029
Mouse
heart looping GO:0001947 94 0.029
positive regulation of signal transduction GO:0009967 56 0.029
inner ear receptor cell differentiation GO:0060113 29 0.029
Zebrafish
aorta development GO:0035904 4 0.029
neuroepithelial cell differentiation GO:0060563 26 0.029
ovulation cycle GO:0042698 2 0.028
pancreas development GO:0031016 84 0.027
Mouse
regulation of synapse assembly GO:0051963 3 0.027
anterior commissure morphogenesis GO:0021960 3 0.027
negative regulation of response to stimulus GO:0048585 104 0.027
homeostatic process GO:0042592 142 0.027
Mouse
regulation of neurological system process GO:0031644 2 0.027
regulation of embryonic development GO:0045995 47 0.026
cellular biosynthetic process GO:0044249 286 0.026
Human Mouse Worm Fly
membrane fusion GO:0061025 2 0.026
oligodendrocyte cell fate specification GO:0021778 4 0.026
branching morphogenesis of an epithelial tube GO:0048754 15 0.026
Human Mouse
programmed cell death GO:0012501 119 0.026
Human Mouse
signal transduction in absence of ligand GO:0038034 1 0.026
single organism organelle organization GO:1902589 199 0.025
response to carbohydrate GO:0009743 3 0.025
Mouse
stem cell fate commitment GO:0048865 1 0.025
inner ear receptor stereocilium organization GO:0060122 8 0.025
system process GO:0003008 185 0.025
mesenchyme development GO:0060485 127 0.025
Mouse
cellular response to chemical stimulus GO:0070887 157 0.024
Mouse
hepaticobiliary system development GO:0061008 98 0.024
regulation of organ growth GO:0046620 3 0.024
floor plate development GO:0033504 15 0.024
regulation of gastrulation GO:0010470 24 0.024
ventral midline development GO:0007418 13 0.024
olfactory lobe development GO:0021988 4 0.024
cell proliferation GO:0008283 80 0.023
Human
regulation of biological quality GO:0065008 263 0.023
Human Mouse
positive regulation of secretion GO:0051047 1 0.023
striated muscle cell proliferation GO:0014855 7 0.023
regulation of jak stat cascade GO:0046425 3 0.023
regulation of multicellular organism growth GO:0040014 4 0.023
endocrine system development GO:0035270 65 0.023
Zebrafish
organic substance biosynthetic process GO:1901576 289 0.023
Human Mouse Worm Fly
cellular component assembly GO:0022607 170 0.023
response to other organism GO:0051707 97 0.023
peptide transport GO:0015833 1 0.022
cilium assembly GO:0042384 58 0.022
cytokine mediated signaling pathway GO:0019221 7 0.022
cellular response to organic substance GO:0071310 105 0.022
Mouse
neuroblast fate commitment GO:0014017 1 0.022
vestibular receptor cell development GO:0060118 3 0.022
Zebrafish
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.022
regulation of heart growth GO:0060420 2 0.022
neuroblast fate determination GO:0007400 1 0.022
response to fibroblast growth factor GO:0071774 22 0.022
embryonic viscerocranium morphogenesis GO:0048703 52 0.021
gliogenesis GO:0042063 45 0.021
Mouse
heart development GO:0007507 313 0.021
inner ear development GO:0048839 126 0.021
Zebrafish Mouse
posterior lateral line neuromast deposition GO:0048922 5 0.021
otic placode formation GO:0043049 23 0.021
Zebrafish
axon extension GO:0048675 45 0.021
cellular response to molecule of bacterial origin GO:0071219 3 0.021
cellular response to endogenous stimulus GO:0071495 68 0.021
cellular component movement GO:0006928 335 0.021
muscle organ development GO:0007517 101 0.021
Fly
negative regulation of cell communication GO:0010648 96 0.021
protein metabolic process GO:0019538 183 0.021
Human Worm
embryonic cranial skeleton morphogenesis GO:0048701 90 0.021
anterior posterior pattern specification GO:0009952 152 0.020
Zebrafish
somite development GO:0061053 96 0.020
central nervous system neuron axonogenesis GO:0021955 18 0.020
regulation of programmed cell death GO:0043067 101 0.020
Human Mouse
single organism metabolic process GO:0044710 217 0.020
Mouse
membrane lipid biosynthetic process GO:0046467 2 0.020
camera type eye development GO:0043010 222 0.020
Zebrafish Mouse Fly
cellular response to growth factor stimulus GO:0071363 39 0.020
positive regulation of stem cell proliferation GO:2000648 1 0.020
blood circulation GO:0008015 87 0.020
forebrain cell migration GO:0021885 1 0.020
blood vessel development GO:0001568 246 0.020
regulation of cellular component organization GO:0051128 86 0.020
Mouse
negative regulation of bmp signaling pathway GO:0030514 13 0.020
response to endogenous stimulus GO:0009719 83 0.020
female gonad development GO:0008585 4 0.019
small molecule metabolic process GO:0044281 77 0.019
posterior lateral line system development GO:0048915 46 0.019
otic vesicle development GO:0071599 42 0.019
Zebrafish
organic substance catabolic process GO:1901575 28 0.019
Worm
vasculature development GO:0001944 278 0.019
regulation of cell migration GO:0030334 40 0.019
gland development GO:0048732 143 0.019
Zebrafish
somitogenesis GO:0001756 87 0.019
embryonic heart tube development GO:0035050 133 0.019
formation of primary germ layer GO:0001704 62 0.019
Mouse
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.019
hormone transport GO:0009914 2 0.019
camera type eye morphogenesis GO:0048593 108 0.018
Zebrafish Mouse Fly
embryonic appendage morphogenesis GO:0035113 30 0.018
retinal ganglion cell axon guidance GO:0031290 35 0.018
regulation of cytokine production GO:0001817 3 0.018
negative regulation of signal transduction GO:0009968 94 0.018
aging GO:0007568 2 0.018
regulation of developmental growth GO:0048638 38 0.018
stem cell proliferation GO:0072089 4 0.018
embryonic skeletal system development GO:0048706 97 0.017
negative regulation of gastrulation GO:2000542 11 0.017
positive regulation of map kinase activity GO:0043406 3 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.017
Human Mouse Worm Fly
otic vesicle morphogenesis GO:0071600 34 0.017
Zebrafish
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 6 0.017
cell proliferation in forebrain GO:0021846 3 0.017
negative regulation of epithelial cell migration GO:0010633 1 0.017
striated muscle tissue development GO:0014706 110 0.017
mesenchymal cell differentiation GO:0048762 87 0.017
Mouse
macromolecular complex subunit organization GO:0043933 74 0.017
odontogenesis of dentin containing tooth GO:0042475 1 0.016
glial cell fate specification GO:0021780 4 0.016
developmental cell growth GO:0048588 52 0.016
neural retina development GO:0003407 49 0.016
Fly
membrane invagination GO:0010324 1 0.016
ventral spinal cord interneuron fate commitment GO:0060579 3 0.016
photoreceptor cell fate commitment GO:0046552 1 0.016
Fly
ovulation cycle process GO:0022602 2 0.016
death GO:0016265 121 0.016
Human Mouse
determination of dorsal ventral asymmetry GO:0048262 34 0.016
spinal cord oligodendrocyte cell fate specification GO:0021530 2 0.016
type b pancreatic cell development GO:0003323 4 0.016
regulation of mechanoreceptor differentiation GO:0045631 1 0.016
positive regulation of neural precursor cell proliferation GO:2000179 1 0.016
hormone secretion GO:0046879 2 0.016
forebrain development GO:0030900 96 0.016
negative regulation of stem cell differentiation GO:2000737 2 0.016
Mouse
muscle cell development GO:0055001 115 0.015
lateral inhibition GO:0046331 1 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.015
multicellular organism reproduction GO:0032504 35 0.015
neuron fate specification GO:0048665 20 0.015
Fly
behavior GO:0007610 74 0.015
lipid metabolic process GO:0006629 52 0.015
neuron projection extension GO:1990138 45 0.015
positive regulation of macromolecule metabolic process GO:0010604 93 0.015
Human Mouse Worm Fly
eye development GO:0001654 277 0.015
Zebrafish Mouse Fly
skeletal muscle organ development GO:0060538 78 0.015
reproductive process GO:0022414 40 0.015
Mouse Worm
growth GO:0040007 174 0.015
olfactory bulb development GO:0021772 4 0.015
wnt signaling pathway GO:0016055 80 0.015
somatic stem cell maintenance GO:0035019 1 0.015
Mouse
regulation of immune system process GO:0002682 34 0.015
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.015
fin morphogenesis GO:0033334 53 0.015
gastrulation with mouth forming second GO:0001702 44 0.015
regulation of protein binding GO:0043393 3 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.014
Human Mouse
sex determination GO:0007530 1 0.014
cardiac cell fate commitment GO:0060911 1 0.014
cardiac chamber development GO:0003205 19 0.014
pharyngeal muscle development GO:0043282 4 0.014
positive regulation of transport GO:0051050 2 0.014
positive regulation of response to stimulus GO:0048584 80 0.014
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.014
cell projection assembly GO:0030031 64 0.014
regulation of bmp signaling pathway GO:0030510 39 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.014
Mouse
embryonic pectoral fin morphogenesis GO:0035118 24 0.014
camera type eye photoreceptor cell differentiation GO:0060219 19 0.014
Fly
angiogenesis GO:0001525 158 0.014
microtubule bundle formation GO:0001578 9 0.014
positive regulation of stress activated mapk cascade GO:0032874 3 0.014
epithelial cell development GO:0002064 42 0.014
Mouse
nephron epithelium morphogenesis GO:0072088 1 0.014
Human Mouse
organelle organization GO:0006996 227 0.014
nephron morphogenesis GO:0072028 2 0.014
Human Mouse
proximal distal pattern formation GO:0009954 1 0.013
skeletal system morphogenesis GO:0048705 102 0.013
regulation of neural precursor cell proliferation GO:2000177 3 0.013
regulation of reproductive process GO:2000241 4 0.013
negative regulation of nucleic acid templated transcription GO:1903507 45 0.013
Human Mouse
ribosomal small subunit biogenesis GO:0042274 2 0.013
negative regulation of endodermal cell fate specification GO:0042664 8 0.013
regulation of cell activation GO:0050865 1 0.013
cartilage development GO:0051216 96 0.013
hemopoiesis GO:0030097 183 0.013
central nervous system neuron differentiation GO:0021953 74 0.013
neural plate development GO:0001840 10 0.013
maintenance of location GO:0051235 4 0.013
immune response GO:0006955 28 0.013
regulation of cardiac muscle tissue development GO:0055024 1 0.013
endodermal cell fate commitment GO:0001711 18 0.013
cilium organization GO:0044782 71 0.013
retina morphogenesis in camera type eye GO:0060042 79 0.013
Fly
response to fungus GO:0009620 25 0.013
muscle structure development GO:0061061 196 0.013
Fly
positive regulation of cell cycle GO:0045787 3 0.012
embryonic heart tube formation GO:0003144 1 0.012
cardiac chamber formation GO:0003207 4 0.012
nerve development GO:0021675 45 0.012
Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.012
Mouse
mesenchymal cell development GO:0014031 78 0.012
regulation of cell motility GO:2000145 46 0.012
lipid storage GO:0019915 1 0.012
auditory receptor cell morphogenesis GO:0002093 4 0.012
ectodermal placode formation GO:0060788 26 0.012
Zebrafish
phosphate containing compound metabolic process GO:0006796 108 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
Human Mouse Worm Fly
lamellipodium organization GO:0097581 1 0.012
sensory perception of chemical stimulus GO:0007606 3 0.012
pronephric nephron development GO:0039019 14 0.012
Zebrafish
posterior lateral line development GO:0048916 38 0.012
regulation of axon extension GO:0030516 24 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
regulation of hormone secretion GO:0046883 2 0.012
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.012
response to organic substance GO:0010033 153 0.012
Mouse
pronephros morphogenesis GO:0072114 14 0.012
Zebrafish
pectoral fin morphogenesis GO:0035138 29 0.012
positive regulation of neuron differentiation GO:0045666 12 0.012
dendrite guidance GO:0070983 0 0.012
formation of anatomical boundary GO:0048859 14 0.012
inner ear receptor cell fate commitment GO:0060120 4 0.011
postsynaptic membrane organization GO:0001941 3 0.011
macroautophagy GO:0016236 1 0.011
regulation of localization GO:0032879 104 0.011
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.011
post anal tail morphogenesis GO:0036342 19 0.011
negative regulation of reproductive process GO:2000242 3 0.011
regulation of hormone levels GO:0010817 21 0.011
positive regulation of nucleic acid templated transcription GO:1903508 57 0.011
Human Mouse Worm Fly
response to biotic stimulus GO:0009607 97 0.011
negative regulation of cytokine production GO:0001818 1 0.011
glucose homeostasis GO:0042593 1 0.011
Mouse
exocrine pancreas development GO:0031017 28 0.011
sex differentiation GO:0007548 5 0.011
Worm
multicellular organismal reproductive process GO:0048609 35 0.011
somatic muscle development GO:0007525 4 0.011
positive regulation of striated muscle tissue development GO:0045844 1 0.011
embryonic eye morphogenesis GO:0048048 30 0.011
Zebrafish Mouse
response to growth factor GO:0070848 39 0.011
regulation of cardiac chamber formation GO:1901210 2 0.011
regulation of establishment of protein localization GO:0070201 4 0.011
fin development GO:0033333 77 0.011
photoreceptor cell differentiation GO:0046530 55 0.011
Fly
ameboidal type cell migration GO:0001667 143 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
Human Mouse
regulation of cellular protein metabolic process GO:0032268 52 0.011
Human
dendrite development GO:0016358 9 0.011
Fly
negative regulation of chromatin modification GO:1903309 1 0.011
reproduction GO:0000003 40 0.010
extrinsic apoptotic signaling pathway GO:0097191 3 0.010
cellular amine metabolic process GO:0044106 2 0.010
polarized epithelial cell differentiation GO:0030859 4 0.010
aorta morphogenesis GO:0035909 3 0.010
negative regulation of protein phosphorylation GO:0001933 4 0.010
phosphorus metabolic process GO:0006793 109 0.010
post embryonic organ morphogenesis GO:0048563 1 0.010
kidney morphogenesis GO:0060993 15 0.010
Human Zebrafish Mouse
carbohydrate homeostasis GO:0033500 1 0.010
Mouse
neural precursor cell proliferation GO:0061351 20 0.010
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.010

pax2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.150
Human
reproductive system disease DOID:15 0 0.150
bone development disease DOID:0080006 0 0.067
bone disease DOID:0080001 0 0.067
musculoskeletal system disease DOID:17 0 0.067
connective tissue disease DOID:65 0 0.067
disease of cellular proliferation DOID:14566 0 0.025
cancer DOID:162 0 0.016
nervous system disease DOID:863 0 0.016
organ system cancer DOID:0050686 0 0.015