Danio rerio

38 known processes

pax3a

paired box gene 3a

(Aliases: zgc:92547,pax3)

pax3a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
central nervous system development GO:0007417 387 0.971
Mouse
heterocycle biosynthetic process GO:0018130 215 0.907
Human Mouse Fly
tube morphogenesis GO:0035239 349 0.825
Mouse
regulation of gene expression GO:0010468 265 0.692
Human Mouse Fly
chordate embryonic development GO:0043009 271 0.619
Mouse
somitogenesis GO:0001756 87 0.603
Mouse
regulation of transcription dna templated GO:0006355 213 0.548
Human Mouse Fly
cellular biosynthetic process GO:0044249 286 0.537
Human Mouse Fly
signal transduction GO:0007165 455 0.527
digestive tract development GO:0048565 265 0.525
digestive system development GO:0055123 289 0.483
hindbrain development GO:0030902 91 0.473
cellular macromolecule biosynthetic process GO:0034645 224 0.462
Human Mouse Fly
positive regulation of biological process GO:0048518 253 0.425
Human Mouse Fly
vasculature development GO:0001944 278 0.423
neuron differentiation GO:0030182 353 0.420
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.417
Human Mouse Fly
heart development GO:0007507 313 0.400
Mouse
embryonic limb morphogenesis GO:0030326 2 0.397
positive regulation of rna metabolic process GO:0051254 59 0.373
Human Mouse Fly
digestive tract morphogenesis GO:0048546 231 0.366
axon development GO:0061564 166 0.353
larval development GO:0002164 2 0.348
Worm
aromatic compound biosynthetic process GO:0019438 217 0.345
Human Mouse Fly
positive regulation of cellular process GO:0048522 201 0.337
Human Mouse Fly
organic substance biosynthetic process GO:1901576 289 0.336
Human Mouse Fly
skeletal muscle organ development GO:0060538 78 0.326
nucleic acid templated transcription GO:0097659 181 0.309
Human Mouse Fly
gastrulation GO:0007369 208 0.290
cell migration GO:0016477 237 0.284
camp metabolic process GO:0046058 11 0.282
regulation of macromolecule metabolic process GO:0060255 317 0.279
Human Mouse Fly
brain development GO:0007420 293 0.278
nitrogen compound metabolic process GO:0006807 319 0.278
Human Mouse Fly
macromolecule biosynthetic process GO:0009059 227 0.275
Human Mouse Fly
muscle organ development GO:0007517 101 0.269
Mouse
lymphatic endothelial cell fate commitment GO:0060838 1 0.269
embryo development ending in birth or egg hatching GO:0009792 271 0.262
Mouse Worm
rna metabolic process GO:0016070 219 0.262
Human Mouse Fly
locomotion GO:0040011 313 0.262
peripheral nervous system neuron differentiation GO:0048934 28 0.261
response to chemical GO:0042221 320 0.258
response to external stimulus GO:0009605 264 0.252
biosynthetic process GO:0009058 294 0.246
Human Mouse Fly
regulation of multicellular organismal development GO:2000026 223 0.243
Mouse
cell morphogenesis GO:0000902 289 0.242
regulation of biosynthetic process GO:0009889 250 0.239
Human Mouse Fly
positive regulation of nucleic acid templated transcription GO:1903508 57 0.238
Human Mouse Fly
transcription dna templated GO:0006351 181 0.236
Human Mouse Fly
cellular component movement GO:0006928 335 0.234
rhombomere 5 morphogenesis GO:0021664 1 0.229
blood vessel development GO:0001568 246 0.223
organic cyclic compound biosynthetic process GO:1901362 223 0.213
Human Mouse Fly
epithelial cell fate commitment GO:0072148 11 0.204
regulation of developmental process GO:0050793 247 0.202
Mouse
embryonic organ morphogenesis GO:0048562 274 0.183
blood vessel morphogenesis GO:0048514 216 0.183
nucleobase containing compound metabolic process GO:0006139 274 0.177
Human Mouse Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.170
Human Mouse Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.164
Human Mouse Fly
auditory receptor cell fate commitment GO:0009912 4 0.162
skeletal muscle tissue development GO:0007519 67 0.162
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.159
axon guidance GO:0007411 86 0.157
development of primary female sexual characteristics GO:0046545 4 0.155
regulation of fatty acid metabolic process GO:0019217 1 0.153
generation of neurons GO:0048699 385 0.151
Mouse
striated muscle tissue development GO:0014706 110 0.149
camera type eye development GO:0043010 222 0.149
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.149
negative regulation of biosynthetic process GO:0009890 55 0.149
Mouse
heart morphogenesis GO:0003007 156 0.142
regulation of response to stimulus GO:0048583 269 0.135
central nervous system neuron development GO:0021954 29 0.135
lipid storage GO:0019915 1 0.134
negative regulation of rna biosynthetic process GO:1902679 45 0.134
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.132
Human Mouse Fly
carboxylic acid metabolic process GO:0019752 22 0.130
olfactory lobe development GO:0021988 4 0.129
positive regulation of macromolecule metabolic process GO:0010604 93 0.127
Human Mouse Fly
organic cyclic compound metabolic process GO:1901360 301 0.127
Human Mouse Fly
localization of cell GO:0051674 244 0.124
endothelial cell fate commitment GO:0060839 3 0.123
cell motility GO:0048870 244 0.120
single organism biosynthetic process GO:0044711 71 0.120
multicellular organismal response to stress GO:0033555 2 0.118
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.117
cell surface receptor signaling pathway GO:0007166 325 0.114
regionalization GO:0003002 274 0.112
Mouse Fly
angiogenesis GO:0001525 158 0.112
central nervous system projection neuron axonogenesis GO:0021952 15 0.112
peripheral nervous system development GO:0007422 55 0.108
embryonic viscerocranium morphogenesis GO:0048703 52 0.108
muscle structure development GO:0061061 196 0.107
Mouse
oxoacid metabolic process GO:0043436 31 0.103
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.101
Human Mouse Fly
system process GO:0003008 185 0.101
neural tube development GO:0021915 62 0.100
Mouse
lymph vessel morphogenesis GO:0036303 25 0.099
cellular macromolecule metabolic process GO:0044260 391 0.098
Human Mouse Fly
negative regulation of rna metabolic process GO:0051253 48 0.097
Mouse
rna biosynthetic process GO:0032774 181 0.097
Human Mouse Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.094
Human Mouse Fly
behavior GO:0007610 74 0.094
Worm
positive regulation of cellular metabolic process GO:0031325 94 0.094
Human Mouse Fly
organic acid metabolic process GO:0006082 31 0.092
negative regulation of neuron projection regeneration GO:0070571 4 0.092
periodic partitioning GO:0007365 1 0.091
Fly
myeloid cell homeostasis GO:0002262 56 0.091
axonogenesis GO:0007409 152 0.091
positive regulation of muscle tissue development GO:1901863 1 0.090
posterior lateral line neuromast hair cell differentiation GO:0048923 8 0.089
appendage development GO:0048736 80 0.084
regulation of metabolic process GO:0019222 359 0.083
Human Mouse Fly
regulation of biological quality GO:0065008 263 0.081
Fly
midbrain development GO:0030901 28 0.081
positive regulation of biosynthetic process GO:0009891 68 0.080
Human Mouse Fly
cell part morphogenesis GO:0032990 246 0.080
determination of bilateral symmetry GO:0009855 204 0.080
negative regulation of transcription dna templated GO:0045892 45 0.079
Mouse
embryonic skeletal system development GO:0048706 97 0.079
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.078
Human Mouse Fly
lymphatic endothelial cell differentiation GO:0060836 1 0.078
response to nutrient GO:0007584 3 0.077
negative regulation of cellular biosynthetic process GO:0031327 55 0.076
Mouse
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.076
nucleoside phosphate biosynthetic process GO:1901293 21 0.075
endocardial cushion formation GO:0003272 2 0.074
mesoderm development GO:0007498 88 0.074
retina layer formation GO:0010842 24 0.074
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.074
Mouse
melanin metabolic process GO:0006582 2 0.073
oocyte maturation GO:0001556 4 0.073
positive regulation of transcription dna templated GO:0045893 57 0.070
Human Mouse Fly
taxis GO:0042330 109 0.069
hindbrain morphogenesis GO:0021575 22 0.069
transcription from rna polymerase ii promoter GO:0006366 80 0.068
Human Mouse Fly
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.068
Human Mouse Fly
central nervous system neuron differentiation GO:0021953 74 0.065
Mouse
lymph vessel development GO:0001945 27 0.064
neuron fate determination GO:0048664 2 0.063
multi organism process GO:0051704 134 0.063
Worm
mesenchyme development GO:0060485 127 0.063
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.061
Human Mouse Fly
axon regeneration GO:0031103 14 0.061
response to vitamin GO:0033273 3 0.060
regulation of rna biosynthetic process GO:2001141 213 0.060
Human Mouse Fly
aging GO:0007568 2 0.059
muscle cell differentiation GO:0042692 139 0.059
regeneration GO:0031099 91 0.058
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.058
retinal metabolic process GO:0042574 3 0.058
head development GO:0060322 303 0.058
mesenchymal cell differentiation GO:0048762 87 0.057
positive regulation of leukocyte differentiation GO:1902107 1 0.057
exocrine system development GO:0035272 28 0.056
Fly
negative regulation of nucleic acid templated transcription GO:1903507 45 0.055
Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.055
Human Mouse Fly
astrocyte differentiation GO:0048708 1 0.054
lymphangiogenesis GO:0001946 25 0.054
proximal distal pattern formation GO:0009954 1 0.054
positive regulation of developmental process GO:0051094 50 0.054
wnt signaling pathway GO:0016055 80 0.053
inner ear morphogenesis GO:0042472 63 0.053
muscle tissue development GO:0060537 110 0.052
regulation of cell proliferation GO:0042127 37 0.051
Mouse
rhombomere morphogenesis GO:0021593 17 0.051
developmental cell growth GO:0048588 52 0.049
stem cell fate determination GO:0048867 1 0.048
anterior posterior pattern specification GO:0009952 152 0.048
Mouse
multicellular organismal reproductive process GO:0048609 35 0.048
Worm
intracellular receptor signaling pathway GO:0030522 30 0.047
adult behavior GO:0030534 2 0.047
growth GO:0040007 174 0.046
negative regulation of cellular process GO:0048523 283 0.046
Mouse
negative regulation of macromolecule metabolic process GO:0010605 76 0.046
Mouse
positive regulation of multicellular organismal process GO:0051240 52 0.046
eye development GO:0001654 277 0.046
neuron projection guidance GO:0097485 86 0.045
regulation of translational initiation GO:0006446 1 0.045
negative regulation of gene expression GO:0010629 65 0.045
Mouse
vasculogenesis GO:0001570 41 0.045
sensory system development GO:0048880 76 0.045
epithelial tube morphogenesis GO:0060562 148 0.044
Mouse
lateral inhibition GO:0046331 1 0.044
endodermal digestive tract morphogenesis GO:0061031 2 0.043
regulation of neurological system process GO:0031644 2 0.043
positive regulation of gene expression GO:0010628 71 0.043
Human Mouse Fly
positive regulation of rna biosynthetic process GO:1902680 57 0.043
Human Mouse Fly
embryonic heart tube development GO:0035050 133 0.042
forebrain regionalization GO:0021871 4 0.042
negative regulation of metabolic process GO:0009892 86 0.042
Mouse
regulation of cyclic nucleotide metabolic process GO:0030799 15 0.042
endocardial cushion morphogenesis GO:0003203 3 0.042
peripheral nervous system neuron development GO:0048935 22 0.040
venous blood vessel development GO:0060841 9 0.040
cellular response to retinoic acid GO:0071300 1 0.040
regulation of inner ear receptor cell differentiation GO:2000980 1 0.039
ameboidal type cell migration GO:0001667 143 0.039
positive regulation of response to stimulus GO:0048584 80 0.038
regulation of anatomical structure morphogenesis GO:0022603 130 0.038
Mouse
cell fate commitment GO:0045165 99 0.038
Mouse
cell proliferation in hindbrain GO:0021534 4 0.037
positive regulation of histone modification GO:0031058 1 0.037
ossification GO:0001503 23 0.037
retinoic acid receptor signaling pathway GO:0048384 16 0.037
regulation of nervous system development GO:0051960 90 0.037
canonical wnt signaling pathway GO:0060070 48 0.036
connective tissue development GO:0061448 99 0.036
positive regulation of chromatin modification GO:1903310 1 0.035
gene expression GO:0010467 252 0.035
Human Mouse Fly
regulation of epithelial cell proliferation GO:0050678 3 0.035
regulation of dna damage response signal transduction by p53 class mediator GO:0043516 4 0.035
hepaticobiliary system development GO:0061008 98 0.035
neuron development GO:0048666 262 0.035
cell migration involved in gastrulation GO:0042074 79 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.034
Mouse
response to oxygen containing compound GO:1901700 55 0.034
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.033
regulation of canonical wnt signaling pathway GO:0060828 34 0.033
nucleic acid metabolic process GO:0090304 244 0.033
Human Mouse Fly
primitive hemopoiesis GO:0060215 27 0.033
regulation of cellular ketone metabolic process GO:0010565 7 0.033
primary neural tube formation GO:0014020 1 0.033
Mouse
response to stress GO:0006950 263 0.033
lipid metabolic process GO:0006629 52 0.032
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.032
Mouse
central nervous system myelination GO:0022010 2 0.031
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.031
Human Mouse Fly
transport GO:0006810 220 0.031
cellular amine metabolic process GO:0044106 2 0.031
posterior lateral line system development GO:0048915 46 0.031
transcription from rna polymerase iii promoter GO:0006383 1 0.030
sprouting angiogenesis GO:0002040 53 0.030
response to lipid GO:0033993 60 0.030
positive regulation of signal transduction GO:0009967 56 0.030
skeletal system morphogenesis GO:0048705 102 0.030
reproduction GO:0000003 40 0.030
Worm
formation of primary germ layer GO:0001704 62 0.030
maintenance of location GO:0051235 4 0.030
skeletal system development GO:0001501 181 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.029
Human Mouse Fly
cell proliferation GO:0008283 80 0.029
Mouse
epithelial cell differentiation GO:0030855 116 0.029
stem cell fate commitment GO:0048865 1 0.029
positive regulation of myeloid cell differentiation GO:0045639 2 0.029
neuron projection morphogenesis GO:0048812 161 0.029
secondary metabolic process GO:0019748 3 0.028
positive regulation of muscle organ development GO:0048636 1 0.028
forebrain development GO:0030900 96 0.028
mitochondrion organization GO:0007005 4 0.027
pharyngeal system development GO:0060037 18 0.027
cell projection organization GO:0030030 284 0.027
neural tube patterning GO:0021532 33 0.026
positive regulation of secretion GO:0051047 1 0.026
embryonic heart tube morphogenesis GO:0003143 108 0.026
cellular protein modification process GO:0006464 100 0.026
positive regulation of glial cell differentiation GO:0045687 1 0.026
cellular ketone metabolic process GO:0042180 11 0.026
homeostasis of number of cells GO:0048872 62 0.025
extrinsic apoptotic signaling pathway GO:0097191 3 0.025
regulation of signaling GO:0023051 235 0.025
Fly
synaptic target recognition GO:0008039 1 0.025
determination of digestive tract left right asymmetry GO:0071907 10 0.025
cyclic nucleotide metabolic process GO:0009187 18 0.025
regulation of cellular metabolic process GO:0031323 320 0.025
Human Mouse Fly
dendrite guidance GO:0070983 0 0.025
neuron projection development GO:0031175 180 0.024
cell fate determination GO:0001709 7 0.024
heterocycle metabolic process GO:0046483 290 0.024
Human Mouse Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.024
Mouse
death GO:0016265 121 0.024
gastrulation with mouth forming second GO:0001702 44 0.024
negative regulation of axon guidance GO:1902668 1 0.024
circulatory system process GO:0003013 87 0.024
anatomical structure arrangement GO:0048532 2 0.024
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.023
somite specification GO:0001757 12 0.023
cellular component morphogenesis GO:0032989 336 0.023
chemosensory behavior GO:0007635 1 0.023
preganglionic parasympathetic nervous system development GO:0021783 6 0.023
response to radiation GO:0009314 51 0.023
female gonad development GO:0008585 4 0.023
mesenchymal cell development GO:0014031 78 0.023
limb bud formation GO:0060174 2 0.023
adherens junction organization GO:0034332 4 0.022
stem cell differentiation GO:0048863 117 0.022
positive regulation of stem cell proliferation GO:2000648 1 0.022
growth plate cartilage development GO:0003417 2 0.022
response to organic substance GO:0010033 153 0.022
establishment of localization GO:0051234 244 0.022
segment polarity determination GO:0007367 1 0.022
Fly
rostrocaudal neural tube patterning GO:0021903 29 0.022
defense response GO:0006952 47 0.022
cellular protein metabolic process GO:0044267 129 0.022
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.022
cartilage development GO:0051216 96 0.022
locomotory behavior GO:0007626 34 0.022
determination of left right symmetry GO:0007368 179 0.022
positive regulation of immune effector process GO:0002699 3 0.021
cell death GO:0008219 121 0.021
anterior commissure morphogenesis GO:0021960 3 0.021
organonitrogen compound biosynthetic process GO:1901566 47 0.021
carbohydrate derivative biosynthetic process GO:1901137 43 0.021
post embryonic organ development GO:0048569 4 0.021
sensory organ morphogenesis GO:0090596 200 0.021
regulation of signal transduction by p53 class mediator GO:1901796 9 0.021
chemotaxis GO:0006935 104 0.020
positive regulation of striated muscle tissue development GO:0045844 1 0.020
response to endogenous stimulus GO:0009719 83 0.020
single organism reproductive process GO:0044702 40 0.020
Worm
positive regulation of cell cycle GO:0045787 3 0.020
epithelial cell development GO:0002064 42 0.020
regulation of cardiac muscle tissue development GO:0055024 1 0.020
chondrocyte development GO:0002063 4 0.020
stem cell development GO:0048864 82 0.020
peripheral nervous system neuron axonogenesis GO:0048936 13 0.020
urogenital system development GO:0001655 97 0.020
posterior lateral line neuromast development GO:0048919 20 0.020
positive regulation of cell communication GO:0010647 56 0.019
rhombomere development GO:0021546 19 0.019
retina development in camera type eye GO:0060041 146 0.019
cellular amino acid metabolic process GO:0006520 7 0.019
regulation of glial cell differentiation GO:0045685 4 0.019
cellular response to organic substance GO:0071310 105 0.019
fat soluble vitamin metabolic process GO:0006775 4 0.019
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.019
convergent extension GO:0060026 118 0.019
axis specification GO:0009798 43 0.019
regulation of skeletal muscle tissue development GO:0048641 4 0.019
centrosome cycle GO:0007098 1 0.018
negative regulation of axon regeneration GO:0048681 4 0.018
dendrite morphogenesis GO:0048813 5 0.018
central nervous system neuron axonogenesis GO:0021955 18 0.018
specification of symmetry GO:0009799 204 0.018
sensory perception GO:0007600 39 0.018
regulation of multicellular organismal process GO:0051239 277 0.017
Mouse
regulation of neural retina development GO:0061074 2 0.017
cellular nitrogen compound metabolic process GO:0034641 290 0.017
Human Mouse Fly
wound healing GO:0042060 90 0.017
kidney development GO:0001822 92 0.017
angioblast cell migration involved in selective angioblast sprouting GO:0035475 4 0.017
apoptotic process GO:0006915 116 0.017
regulation of neuron migration GO:2001222 2 0.017
g1 s transition of mitotic cell cycle GO:0000082 1 0.017
positive regulation of secretion by cell GO:1903532 1 0.017
regulation of mechanoreceptor differentiation GO:0045631 1 0.017
startle response GO:0001964 4 0.017
polarized epithelial cell differentiation GO:0030859 4 0.017
female sex differentiation GO:0046660 4 0.017
determination of heart left right asymmetry GO:0061371 117 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
diterpenoid metabolic process GO:0016101 15 0.017
heart contraction GO:0060047 71 0.017
small molecule metabolic process GO:0044281 77 0.017
regulation of heart growth GO:0060420 2 0.016
branching morphogenesis of a nerve GO:0048755 4 0.016
embryonic appendage morphogenesis GO:0035113 30 0.016
cellular aldehyde metabolic process GO:0006081 4 0.016
protein metabolic process GO:0019538 183 0.016
regulation of primary metabolic process GO:0080090 311 0.016
Human Mouse Fly
positive regulation of cytokine production GO:0001819 2 0.016
response to other organism GO:0051707 97 0.016
muscle fiber development GO:0048747 52 0.016
liver development GO:0001889 96 0.016
embryonic skeletal system morphogenesis GO:0048704 93 0.016
cell proliferation in forebrain GO:0021846 3 0.016
leukocyte differentiation GO:0002521 25 0.016
phosphate containing compound metabolic process GO:0006796 108 0.015
endothelial cell differentiation GO:0045446 20 0.015
endoderm development GO:0007492 49 0.015
negative regulation of collateral sprouting of intact axon in response to injury GO:0048685 2 0.015
positive regulation of jak stat cascade GO:0046427 2 0.015
determination of intestine left right asymmetry GO:0071908 2 0.015
developmental growth involved in morphogenesis GO:0060560 86 0.015
response to external biotic stimulus GO:0043207 97 0.015
neuron recognition GO:0008038 18 0.015
positive regulation of translation GO:0045727 1 0.014
facial nerve morphogenesis GO:0021610 1 0.014
macromolecule modification GO:0043412 111 0.014
proteasomal protein catabolic process GO:0010498 2 0.014
inner ear receptor cell fate commitment GO:0060120 4 0.014
venous blood vessel morphogenesis GO:0048845 3 0.014
regulation of bone mineralization GO:0030500 2 0.014
camera type eye morphogenesis GO:0048593 108 0.014
positive regulation of muscle cell differentiation GO:0051149 1 0.014
positive regulation of striated muscle cell differentiation GO:0051155 1 0.014
negative regulation of epithelial cell proliferation GO:0050680 1 0.014
endocrine system development GO:0035270 65 0.014
embryonic organ development GO:0048568 381 0.014
chromatin modification GO:0016568 21 0.014
response to acid chemical GO:0001101 17 0.014
positive regulation of nervous system development GO:0051962 25 0.014
neuroblast differentiation GO:0014016 1 0.014
epidermis development GO:0008544 48 0.014
septum transversum development GO:0003343 4 0.014
enzyme linked receptor protein signaling pathway GO:0007167 106 0.014
programmed cell death GO:0012501 119 0.014
single organism metabolic process GO:0044710 217 0.014
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.014
cell substrate junction assembly GO:0007044 2 0.014
Worm
embryonic cranial skeleton morphogenesis GO:0048701 90 0.013
negative regulation of cellular metabolic process GO:0031324 77 0.013
Mouse
regulation of cytokine production GO:0001817 3 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.013
Human Mouse Fly
rhombomere 6 development GO:0021572 4 0.013
negative regulation of biological process GO:0048519 304 0.013
Mouse
positive regulation of oligodendrocyte differentiation GO:0048714 1 0.013
positive regulation of cellular biosynthetic process GO:0031328 68 0.013
Human Mouse Fly
midbrain hindbrain boundary development GO:0030917 23 0.013
negative regulation of wnt signaling pathway GO:0030178 30 0.013
multicellular organism reproduction GO:0032504 35 0.013
Worm
positive regulation of gliogenesis GO:0014015 2 0.013
stem cell proliferation GO:0072089 4 0.013
myeloid cell differentiation GO:0030099 86 0.013
extracellular structure organization GO:0043062 27 0.013
segmentation GO:0035282 97 0.013
Mouse Fly
regulation of tube size GO:0035150 2 0.013
positive regulation of cell differentiation GO:0045597 30 0.013
ear development GO:0043583 127 0.013
retinal ganglion cell axon guidance GO:0031290 35 0.013
appendage morphogenesis GO:0035107 56 0.013
negative regulation of collateral sprouting GO:0048671 2 0.013
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.013
auditory receptor cell fate determination GO:0042668 2 0.013
positive regulation of metabolic process GO:0009893 108 0.012
Human Mouse Fly
cation transport GO:0006812 81 0.012
neural retina development GO:0003407 49 0.012
blood vessel endothelial cell migration GO:0043534 18 0.012
neuron migration GO:0001764 22 0.012
mesodermal cell migration GO:0008078 12 0.012
renal tubule morphogenesis GO:0061333 1 0.012
multicellular organism growth GO:0035264 4 0.012
negative regulation of programmed cell death GO:0043069 58 0.012
regulation of myelination GO:0031641 1 0.012
terpenoid metabolic process GO:0006721 15 0.012
endodermal cell fate determination GO:0007493 2 0.012
tissue regeneration GO:0042246 74 0.012
regulation of signal transduction GO:0009966 225 0.012
paraxial mesoderm morphogenesis GO:0048340 2 0.012
embryonic heart tube formation GO:0003144 1 0.012
protein secretion GO:0009306 1 0.011
cellular protein catabolic process GO:0044257 4 0.011
regulation of blood pressure GO:0008217 1 0.011
gamete generation GO:0007276 33 0.011
syncytium formation by plasma membrane fusion GO:0000768 12 0.011
embryonic digestive tract development GO:0048566 4 0.011
regulation of oligodendrocyte differentiation GO:0048713 1 0.011
smoothened signaling pathway GO:0007224 30 0.011
myeloid leukocyte differentiation GO:0002573 15 0.011
cell projection morphogenesis GO:0048858 244 0.011
developmental programmed cell death GO:0010623 4 0.011
protein modification process GO:0036211 100 0.011
vascular endothelial growth factor receptor signaling pathway GO:0048010 13 0.011
embryonic digestive tract morphogenesis GO:0048557 3 0.011
developmental process involved in reproduction GO:0003006 27 0.011
Worm
regulation of myotube differentiation GO:0010830 2 0.011
regulation of reproductive process GO:2000241 4 0.011
positive regulation of chromosome organization GO:2001252 1 0.011
convergent extension involved in gastrulation GO:0060027 71 0.011
somite development GO:0061053 96 0.011
Mouse
morphogenesis of embryonic epithelium GO:0016331 30 0.011
Mouse
motor neuron axon guidance GO:0008045 23 0.010
neural precursor cell proliferation GO:0061351 20 0.010
regulation of calcium ion transport into cytosol GO:0010522 1 0.010
monocarboxylic acid metabolic process GO:0032787 17 0.010
regulation of jak stat cascade GO:0046425 3 0.010
paraxial mesoderm formation GO:0048341 2 0.010
heart looping GO:0001947 94 0.010
neuromast development GO:0048884 46 0.010
regulation of multicellular organism growth GO:0040014 4 0.010
positive regulation of signaling GO:0023056 56 0.010
anterior lateral line system development GO:0048898 9 0.010
cyclic nucleotide biosynthetic process GO:0009190 18 0.010

pax3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
charcot marie tooth disease type 4 DOID:0050541 0 0.078
neuromuscular disease DOID:440 0 0.078
disease of anatomical entity DOID:7 0 0.078
charcot marie tooth disease DOID:10595 0 0.078
nervous system disease DOID:863 0 0.078
neuropathy DOID:870 0 0.078
cancer DOID:162 0 0.063
Human
disease of cellular proliferation DOID:14566 0 0.063
Human
organ system cancer DOID:0050686 0 0.063
Human
musculoskeletal system disease DOID:17 0 0.029
connective tissue disease DOID:65 0 0.029
bone development disease DOID:0080006 0 0.029
bone disease DOID:0080001 0 0.029
disease of mental health DOID:150 0 0.017
developmental disorder of mental health DOID:0060037 0 0.017
physical disorder DOID:0080015 0 0.010