Danio rerio

0 known processes

pbrm1l

polybromo 1, like

(Aliases: zgc:100857,MGC113882,pb1,zgc:113882)

pbrm1l biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.378
regulation of primary metabolic process GO:0080090 311 0.318
rna metabolic process GO:0016070 219 0.313
cellular biosynthetic process GO:0044249 286 0.289
nitrogen compound metabolic process GO:0006807 319 0.231
regulation of chromosome segregation GO:0051983 1 0.218
cellular macromolecule metabolic process GO:0044260 391 0.211
nucleic acid metabolic process GO:0090304 244 0.185
regulation of nitrogen compound metabolic process GO:0051171 251 0.177
chromosome organization GO:0051276 31 0.177
internal peptidyl lysine acetylation GO:0018393 2 0.167
regulation of protein complex assembly GO:0043254 3 0.151
embryo development ending in birth or egg hatching GO:0009792 271 0.151
regulation of gene expression GO:0010468 265 0.149
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.147
organic cyclic compound metabolic process GO:1901360 301 0.143
internal protein amino acid acetylation GO:0006475 2 0.136
chromatin modification GO:0016568 21 0.125
ubiquitin dependent protein catabolic process GO:0006511 3 0.118
heterocycle metabolic process GO:0046483 290 0.116
macromolecule modification GO:0043412 111 0.116
cellular protein catabolic process GO:0044257 4 0.115
regulation of protein catabolic process GO:0042176 1 0.108
protein acetylation GO:0006473 2 0.104
nucleobase containing compound biosynthetic process GO:0034654 205 0.103
negative regulation of biological process GO:0048519 304 0.100
modification dependent protein catabolic process GO:0019941 3 0.099
cellular nitrogen compound metabolic process GO:0034641 290 0.098
heart development GO:0007507 313 0.095
organelle organization GO:0006996 227 0.091
cellular nitrogen compound biosynthetic process GO:0044271 218 0.086
maintenance of location GO:0051235 4 0.086
protein acylation GO:0043543 3 0.084
meiotic cell cycle process GO:1903046 3 0.081
regulation of rna metabolic process GO:0051252 224 0.081
proteasomal protein catabolic process GO:0010498 2 0.080
organic substance biosynthetic process GO:1901576 289 0.076
regulation of multicellular organismal process GO:0051239 277 0.074
meiotic nuclear division GO:0007126 4 0.072
macromolecular complex subunit organization GO:0043933 74 0.064
heterocycle biosynthetic process GO:0018130 215 0.064
nucleobase containing compound metabolic process GO:0006139 274 0.063
embryonic organ development GO:0048568 381 0.062
single organism organelle organization GO:1902589 199 0.061
negative regulation of metabolic process GO:0009892 86 0.061
multicellular organism growth GO:0035264 4 0.061
biosynthetic process GO:0009058 294 0.061
negative regulation of nuclear division GO:0051784 3 0.060
positive regulation of cell cycle GO:0045787 3 0.059
cellular component movement GO:0006928 335 0.059
regulation of macromolecule metabolic process GO:0060255 317 0.059
organic cyclic compound biosynthetic process GO:1901362 223 0.058
rna biosynthetic process GO:0032774 181 0.058
regulation of multicellular organism growth GO:0040014 4 0.056
gene expression GO:0010467 252 0.055
aromatic compound biosynthetic process GO:0019438 217 0.054
response to stress GO:0006950 263 0.054
tube morphogenesis GO:0035239 349 0.054
regulation of cellular protein catabolic process GO:1903362 1 0.053
negative regulation of cellular process GO:0048523 283 0.052
protein metabolic process GO:0019538 183 0.052
nucleic acid templated transcription GO:0097659 181 0.051
developmental growth GO:0048589 166 0.050
rna polyadenylation GO:0043631 2 0.050
mitotic sister chromatid segregation GO:0000070 6 0.050
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.050
regulation of macromolecule biosynthetic process GO:0010556 225 0.049
regulation of dna replication GO:0006275 3 0.048
regulation of cellular metabolic process GO:0031323 320 0.048
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.045
cellular component morphogenesis GO:0032989 336 0.045
locomotion GO:0040011 313 0.044
positive regulation of chromatin modification GO:1903310 1 0.044
transcription dna templated GO:0006351 181 0.043
cellular aromatic compound metabolic process GO:0006725 295 0.043
regulation of cellular biosynthetic process GO:0031326 245 0.042
regionalization GO:0003002 274 0.041
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.041
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.041
positive regulation of cellular component biogenesis GO:0044089 3 0.040
cellular macromolecule biosynthetic process GO:0034645 224 0.040
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.040
regulation of organelle assembly GO:1902115 4 0.039
modification dependent macromolecule catabolic process GO:0043632 3 0.038
localization of cell GO:0051674 244 0.038
cellular component biogenesis GO:0044085 178 0.037
meiotic chromosome segregation GO:0045132 3 0.037
negative regulation of cellular metabolic process GO:0031324 77 0.037
sister chromatid cohesion GO:0007062 2 0.036
embryonic heart tube morphogenesis GO:0003143 108 0.036
negative regulation of synapse assembly GO:0051964 2 0.036
protein modification process GO:0036211 100 0.035
regulation of nucleic acid templated transcription GO:1903506 213 0.035
macromolecule biosynthetic process GO:0009059 227 0.034
regulation of metabolic process GO:0019222 359 0.033
positive regulation of biological process GO:0048518 253 0.033
regulation of transcription dna templated GO:0006355 213 0.033
transport GO:0006810 220 0.033
negative regulation of catabolic process GO:0009895 3 0.033
negative regulation of dna metabolic process GO:0051053 4 0.033
neuron projection development GO:0031175 180 0.032
regulation of rna biosynthetic process GO:2001141 213 0.032
chromosome segregation GO:0007059 12 0.032
regulation of cell activation GO:0050865 1 0.031
aging GO:0007568 2 0.030
determination of bilateral symmetry GO:0009855 204 0.030
regulation of biosynthetic process GO:0009889 250 0.030
neuroblast proliferation GO:0007405 2 0.029
embryonic organ morphogenesis GO:0048562 274 0.029
single organism localization GO:1902578 225 0.029
cellular protein metabolic process GO:0044267 129 0.029
negative regulation of mitosis GO:0045839 3 0.029
regulation of organelle organization GO:0033043 29 0.028
positive regulation of transport GO:0051050 2 0.028
cytokinesis GO:0000910 3 0.028
positive regulation of chromosome organization GO:2001252 1 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.027
protein alkylation GO:0008213 13 0.026
regulation of biological quality GO:0065008 263 0.026
regulation of histone methylation GO:0031060 3 0.026
macromolecule methylation GO:0043414 19 0.026
sister chromatid segregation GO:0000819 6 0.025
cell morphogenesis GO:0000902 289 0.024
positive regulation of dna metabolic process GO:0051054 1 0.024
negative regulation of dna replication GO:0008156 2 0.024
establishment of localization GO:0051234 244 0.023
negative regulation of gene expression GO:0010629 65 0.023
oxoacid metabolic process GO:0043436 31 0.023
negative regulation of macromolecule metabolic process GO:0010605 76 0.023
negative regulation of rna metabolic process GO:0051253 48 0.023
cellular protein modification process GO:0006464 100 0.022
regulation of microtubule cytoskeleton organization GO:0070507 3 0.022
multi organism cellular process GO:0044764 2 0.022
cell morphogenesis involved in differentiation GO:0000904 195 0.022
heart morphogenesis GO:0003007 156 0.022
homeostatic process GO:0042592 142 0.021
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.021
protein stabilization GO:0050821 2 0.021
multi organism process GO:0051704 134 0.021
chromatin organization GO:0006325 22 0.021
histone modification GO:0016570 20 0.021
protein complex assembly GO:0006461 30 0.021
positive regulation of cytoskeleton organization GO:0051495 3 0.020
peptidyl lysine acetylation GO:0018394 2 0.020
immune system development GO:0002520 191 0.020
single organism nuclear import GO:1902593 3 0.020
myeloid cell differentiation GO:0030099 86 0.020
establishment of protein localization to organelle GO:0072594 4 0.020
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.020
oocyte anterior posterior axis specification GO:0007314 4 0.019
regulation of dna metabolic process GO:0051052 11 0.019
regulation of developmental process GO:0050793 247 0.019
positive regulation of cell activation GO:0050867 1 0.019
negative regulation of cellular catabolic process GO:0031330 3 0.018
organic acid metabolic process GO:0006082 31 0.018
negative regulation of protein phosphorylation GO:0001933 4 0.018
carboxylic acid metabolic process GO:0019752 22 0.018
morphogenesis of an epithelium GO:0002009 333 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
histone h3 k36 methylation GO:0010452 2 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.018
cell projection organization GO:0030030 284 0.018
embryonic skeletal joint morphogenesis GO:0060272 3 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.018
negative regulation of biosynthetic process GO:0009890 55 0.018
single organism metabolic process GO:0044710 217 0.018
epithelial tube morphogenesis GO:0060562 148 0.018
regulation of synapse organization GO:0050807 3 0.018
somitogenesis GO:0001756 87 0.018
regulation of cellular protein metabolic process GO:0032268 52 0.017
rna localization GO:0006403 4 0.017
rna 3 end processing GO:0031123 2 0.017
regulation of cellular ketone metabolic process GO:0010565 7 0.017
protein localization to nucleus GO:0034504 3 0.017
positive regulation of multi organism process GO:0043902 3 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
regulation of synapse assembly GO:0051963 3 0.017
nuclear import GO:0051170 3 0.017
mononuclear cell proliferation GO:0032943 1 0.016
protein methylation GO:0006479 13 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
positive regulation of macromolecule metabolic process GO:0010604 93 0.016
macromolecular complex assembly GO:0065003 35 0.016
amine metabolic process GO:0009308 2 0.016
cell projection morphogenesis GO:0048858 244 0.016
liver development GO:0001889 96 0.016
determination of left right symmetry GO:0007368 179 0.016
meiosis ii GO:0007135 1 0.016
mrna polyadenylation GO:0006378 2 0.016
covalent chromatin modification GO:0016569 20 0.016
translational initiation GO:0006413 3 0.015
muscle structure development GO:0061061 196 0.015
actin filament based process GO:0030029 64 0.015
chordate embryonic development GO:0043009 271 0.015
regulation of cell cycle phase transition GO:1901987 8 0.015
cellular response to dsrna GO:0071359 1 0.015
lipid storage GO:0019915 1 0.015
epithelial cell morphogenesis GO:0003382 2 0.015
atp catabolic process GO:0006200 4 0.015
cellular amine metabolic process GO:0044106 2 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.015
fertilization GO:0009566 3 0.015
histone methylation GO:0016571 13 0.015
cell cycle g1 s phase transition GO:0044843 1 0.014
mitotic sister chromatid cohesion GO:0007064 2 0.014
mrna metabolic process GO:0016071 20 0.014
interspecies interaction between organisms GO:0044419 4 0.014
cell part morphogenesis GO:0032990 246 0.014
mesenchymal cell differentiation GO:0048762 87 0.014
regulation of establishment of protein localization GO:0070201 4 0.014
anterior posterior pattern specification GO:0009952 152 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
b cell activation GO:0042113 2 0.014
gastrulation GO:0007369 208 0.014
cellular component assembly GO:0022607 170 0.014
mesenchyme development GO:0060485 127 0.014
lymphocyte proliferation GO:0046651 1 0.014
extrinsic apoptotic signaling pathway GO:0097191 3 0.014
forebrain anterior posterior pattern specification GO:0021797 3 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.014
response to chemical GO:0042221 320 0.013
regulation of mitotic cell cycle phase transition GO:1901990 8 0.013
specification of symmetry GO:0009799 204 0.013
chromosome localization GO:0050000 2 0.013
female gonad development GO:0008585 4 0.013
protein heterooligomerization GO:0051291 1 0.013
neuron projection morphogenesis GO:0048812 161 0.013
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.013
digestive system development GO:0055123 289 0.013
spermatid differentiation GO:0048515 2 0.013
cell migration GO:0016477 237 0.013
production of molecular mediator of immune response GO:0002440 2 0.012
embryonic cranial skeleton morphogenesis GO:0048701 90 0.012
digestive tract morphogenesis GO:0048546 231 0.012
negative regulation of cellular biosynthetic process GO:0031327 55 0.012
negative regulation of defense response GO:0031348 2 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
positive regulation of catabolic process GO:0009896 4 0.012
reproduction GO:0000003 40 0.012
immune system process GO:0002376 241 0.012
cell cycle process GO:0022402 53 0.012
phagocytosis GO:0006909 3 0.012
regulation of dna recombination GO:0000018 2 0.012
negative regulation of nucleic acid templated transcription GO:1903507 45 0.012
regulation of mitosis GO:0007088 9 0.012
response to oxidative stress GO:0006979 11 0.012
ribonucleoside monophosphate catabolic process GO:0009158 4 0.012
regulation of protein metabolic process GO:0051246 56 0.012
spindle assembly involved in mitosis GO:0090307 1 0.012
embryonic digestive tract morphogenesis GO:0048557 3 0.012
sensory organ morphogenesis GO:0090596 200 0.012
striated muscle cell differentiation GO:0051146 129 0.012
protein complex subunit organization GO:0071822 46 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
neuron projection guidance GO:0097485 86 0.012
neuron differentiation GO:0030182 353 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.012
cytoskeleton dependent cytokinesis GO:0061640 3 0.012
female sex differentiation GO:0046660 4 0.012
hemopoiesis GO:0030097 183 0.012
growth GO:0040007 174 0.012
signal transduction GO:0007165 455 0.012
methylation GO:0032259 22 0.012
adult behavior GO:0030534 2 0.012
regulation of nucleocytoplasmic transport GO:0046822 2 0.012
regulation of cellular component organization GO:0051128 86 0.012
chromosome organization involved in meiosis GO:0070192 1 0.011
somite development GO:0061053 96 0.011
blood vessel morphogenesis GO:0048514 216 0.011
mitotic cell cycle process GO:1903047 48 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
camera type eye development GO:0043010 222 0.011
viral process GO:0016032 1 0.011
cellular ketone metabolic process GO:0042180 11 0.011
oogenesis GO:0048477 14 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
protein modification by small protein conjugation or removal GO:0070647 14 0.011
negative regulation of transcription dna templated GO:0045892 45 0.011
negative regulation of multi organism process GO:0043901 3 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
retina morphogenesis in camera type eye GO:0060042 79 0.011
organelle localization GO:0051640 49 0.011
axonogenesis GO:0007409 152 0.011
cellular carbohydrate metabolic process GO:0044262 4 0.011
small molecule metabolic process GO:0044281 77 0.011
nucleocytoplasmic transport GO:0006913 4 0.011
adherens junction organization GO:0034332 4 0.011
response to carbohydrate GO:0009743 3 0.011
protein import GO:0017038 3 0.011
negative regulation of chromosome organization GO:2001251 1 0.011
nuclear division GO:0000280 23 0.011
regulation of cell differentiation GO:0045595 142 0.011
neuron development GO:0048666 262 0.011
immunoglobulin mediated immune response GO:0016064 3 0.011
regulation of reproductive process GO:2000241 4 0.011
regulation of production of molecular mediator of immune response GO:0002700 1 0.011
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.011
protein polyubiquitination GO:0000209 4 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
wound healing GO:0042060 90 0.011
regulation of developmental growth GO:0048638 38 0.010
cell motility GO:0048870 244 0.010
organelle fission GO:0048285 23 0.010
embryonic heart tube development GO:0035050 133 0.010
pancreas development GO:0031016 84 0.010
cytoskeleton organization GO:0007010 96 0.010
peptidyl lysine methylation GO:0018022 3 0.010
cell cycle GO:0007049 93 0.010
vasculature development GO:0001944 278 0.010
stem cell division GO:0017145 1 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.010
rna export from nucleus GO:0006405 1 0.010

pbrm1l disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.076
nervous system disease DOID:863 0 0.061
motor neuron disease DOID:231 0 0.012
neurodegenerative disease DOID:1289 0 0.012
central nervous system disease DOID:331 0 0.012
amyotrophic lateral sclerosis DOID:332 0 0.012