Danio rerio

31 known processes

pbx1a

pre-B-cell leukemia transcription factor 1a

(Aliases: wu:fi29e01,zgc:55265,fi29e01,pbx1b)

pbx1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
brain development GO:0007420 293 0.941
head development GO:0060322 303 0.835
central nervous system development GO:0007417 387 0.834
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.668
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.645
embryonic organ development GO:0048568 381 0.568
embryonic organ morphogenesis GO:0048562 274 0.544
negative regulation of biosynthetic process GO:0009890 55 0.531
nitrogen compound metabolic process GO:0006807 319 0.525
regulation of nucleic acid templated transcription GO:1903506 213 0.506
regulation of transcription dna templated GO:0006355 213 0.503
nucleobase containing compound biosynthetic process GO:0034654 205 0.491
locomotion GO:0040011 313 0.470
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.454
organic substance biosynthetic process GO:1901576 289 0.422
organic cyclic compound metabolic process GO:1901360 301 0.418
nucleic acid metabolic process GO:0090304 244 0.406
larval development GO:0002164 2 0.400
biosynthetic process GO:0009058 294 0.387
negative regulation of biological process GO:0048519 304 0.384
transcription dna templated GO:0006351 181 0.376
cellular nitrogen compound metabolic process GO:0034641 290 0.365
regulation of cellular metabolic process GO:0031323 320 0.352
embryonic heart tube morphogenesis GO:0003143 108 0.350
embryo development ending in birth or egg hatching GO:0009792 271 0.337
neuron projection development GO:0031175 180 0.334
organic cyclic compound biosynthetic process GO:1901362 223 0.324
nucleobase containing compound metabolic process GO:0006139 274 0.307
regulation of primary metabolic process GO:0080090 311 0.294
cellular aromatic compound metabolic process GO:0006725 295 0.287
regulation of biosynthetic process GO:0009889 250 0.269
macromolecule biosynthetic process GO:0009059 227 0.267
regulation of cell differentiation GO:0045595 142 0.251
cellular nitrogen compound biosynthetic process GO:0044271 218 0.250
skeletal system development GO:0001501 181 0.249
regulation of macromolecule biosynthetic process GO:0010556 225 0.241
cellular macromolecule biosynthetic process GO:0034645 224 0.238
specification of symmetry GO:0009799 204 0.238
establishment of localization GO:0051234 244 0.233
positive regulation of biosynthetic process GO:0009891 68 0.226
negative regulation of macromolecule metabolic process GO:0010605 76 0.214
rna metabolic process GO:0016070 219 0.214
regulation of cellular biosynthetic process GO:0031326 245 0.213
positive regulation of cell differentiation GO:0045597 30 0.207
positive regulation of rna metabolic process GO:0051254 59 0.206
positive regulation of metabolic process GO:0009893 108 0.196
embryonic heart tube development GO:0035050 133 0.193
heterocycle metabolic process GO:0046483 290 0.191
positive regulation of cellular metabolic process GO:0031325 94 0.186
negative regulation of multicellular organismal process GO:0051241 69 0.186
aging GO:0007568 2 0.182
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.180
regulation of gene expression GO:0010468 265 0.178
cell death GO:0008219 121 0.178
behavior GO:0007610 74 0.174
single organism biosynthetic process GO:0044711 71 0.173
determination of left right symmetry GO:0007368 179 0.167
regulation of metabolic process GO:0019222 359 0.166
muscle structure development GO:0061061 196 0.165
heart development GO:0007507 313 0.162
negative regulation of metabolic process GO:0009892 86 0.161
response to external stimulus GO:0009605 264 0.156
sensory organ morphogenesis GO:0090596 200 0.155
regulation of developmental process GO:0050793 247 0.150
mesenchyme development GO:0060485 127 0.150
eye morphogenesis GO:0048592 144 0.147
cellular biosynthetic process GO:0044249 286 0.146
rna biosynthetic process GO:0032774 181 0.142
regulation of rna metabolic process GO:0051252 224 0.136
protein secretion GO:0009306 1 0.133
gene expression GO:0010467 252 0.130
negative regulation of cellular biosynthetic process GO:0031327 55 0.129
heart looping GO:0001947 94 0.125
regulation of stem cell proliferation GO:0072091 2 0.123
regulation of nitrogen compound metabolic process GO:0051171 251 0.120
myotube differentiation GO:0014902 45 0.118
generation of neurons GO:0048699 385 0.117
hindbrain development GO:0030902 91 0.115
forebrain development GO:0030900 96 0.110
response to carbohydrate GO:0009743 3 0.106
aromatic compound biosynthetic process GO:0019438 217 0.106
regulation of neurogenesis GO:0050767 87 0.106
transcription from rna polymerase ii promoter GO:0006366 80 0.105
regulation of locomotion GO:0040012 55 0.105
cardiocyte differentiation GO:0035051 44 0.104
olfactory bulb development GO:0021772 4 0.101
transport GO:0006810 220 0.099
cellular response to chemical stimulus GO:0070887 157 0.096
negative regulation of developmental process GO:0051093 65 0.094
hindbrain morphogenesis GO:0021575 22 0.092
phagocytosis GO:0006909 3 0.091
cell migration GO:0016477 237 0.090
nucleic acid templated transcription GO:0097659 181 0.090
response to lipid GO:0033993 60 0.090
response to stress GO:0006950 263 0.089
positive regulation of cellular process GO:0048522 201 0.088
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.088
response to glucose GO:0009749 3 0.086
negative regulation of cellular metabolic process GO:0031324 77 0.086
regulation of mrna catabolic process GO:0061013 3 0.085
negative regulation of nucleic acid templated transcription GO:1903507 45 0.085
negative regulation of cellular process GO:0048523 283 0.084
response to oxygen containing compound GO:1901700 55 0.082
cell projection organization GO:0030030 284 0.081
cell substrate adhesion GO:0031589 4 0.081
neuron differentiation GO:0030182 353 0.080
response to alkaloid GO:0043279 2 0.079
cellular response to stress GO:0033554 62 0.078
positive regulation of biological process GO:0048518 253 0.078
positive regulation of catabolic process GO:0009896 4 0.078
regulation of macromolecule metabolic process GO:0060255 317 0.077
glucose homeostasis GO:0042593 1 0.077
g protein coupled receptor signaling pathway GO:0007186 74 0.075
system process GO:0003008 185 0.074
heterocycle biosynthetic process GO:0018130 215 0.074
negative regulation of rna metabolic process GO:0051253 48 0.073
positive regulation of gene expression GO:0010628 71 0.073
skeletal system morphogenesis GO:0048705 102 0.073
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.072
actin cytoskeleton organization GO:0030036 63 0.072
regulation of multicellular organismal process GO:0051239 277 0.072
lipid biosynthetic process GO:0008610 22 0.072
response to chemical GO:0042221 320 0.071
positive regulation of nervous system development GO:0051962 25 0.071
regulation of response to stimulus GO:0048583 269 0.071
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.070
cell motility GO:0048870 244 0.070
single organism metabolic process GO:0044710 217 0.070
positive regulation of macromolecule metabolic process GO:0010604 93 0.069
cellular component movement GO:0006928 335 0.069
cytoskeleton organization GO:0007010 96 0.068
multicellular organismal water homeostasis GO:0050891 1 0.068
heart morphogenesis GO:0003007 156 0.068
autophagy GO:0006914 4 0.066
specification of axis polarity GO:0065001 4 0.065
localization of cell GO:0051674 244 0.065
appendage development GO:0048736 80 0.065
determination of bilateral symmetry GO:0009855 204 0.065
cellular component assembly GO:0022607 170 0.064
negative regulation of gene expression GO:0010629 65 0.064
calcium ion transport into cytosol GO:0060402 3 0.063
photoreceptor cell development GO:0042461 40 0.062
regulation of rna biosynthetic process GO:2001141 213 0.060
neuron neuron synaptic transmission GO:0007270 1 0.060
mechanosensory lateral line system development GO:0048881 49 0.060
muscle cell differentiation GO:0042692 139 0.059
retina development in camera type eye GO:0060041 146 0.059
olfactory lobe development GO:0021988 4 0.059
multi organism reproductive process GO:0044703 36 0.058
determination of heart left right asymmetry GO:0061371 117 0.058
regulation of multicellular organismal development GO:2000026 223 0.058
positive regulation of apoptotic process GO:0043065 29 0.057
regulation of transcription involved in cell fate commitment GO:0060850 1 0.056
cellular macromolecule metabolic process GO:0044260 391 0.056
neuromuscular process controlling balance GO:0050885 3 0.055
immune system process GO:0002376 241 0.055
morphogenesis of an epithelium GO:0002009 333 0.054
fertilization GO:0009566 3 0.054
water homeostasis GO:0030104 4 0.054
maintenance of location GO:0051235 4 0.054
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.054
striated muscle cell differentiation GO:0051146 129 0.053
neural retina development GO:0003407 49 0.053
posterior lateral line system development GO:0048915 46 0.052
positive regulation of transport GO:0051050 2 0.051
negative regulation of rna biosynthetic process GO:1902679 45 0.051
regulation of cellular component movement GO:0051270 55 0.051
response to monosaccharide GO:0034284 3 0.051
regulation of response to extracellular stimulus GO:0032104 1 0.050
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.050
phosphorylation GO:0016310 69 0.050
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.049
regulation of cell substrate adhesion GO:0010810 1 0.049
regulation of signaling GO:0023051 235 0.049
retina morphogenesis in camera type eye GO:0060042 79 0.048
positive regulation of rna biosynthetic process GO:1902680 57 0.047
regulation of peptidase activity GO:0052547 23 0.047
negative regulation of transcription dna templated GO:0045892 45 0.047
transmission of nerve impulse GO:0019226 19 0.047
regulation of behavior GO:0050795 24 0.046
chordate embryonic development GO:0043009 271 0.046
camera type eye photoreceptor cell differentiation GO:0060219 19 0.046
lateral line development GO:0048882 66 0.046
regulation of biological quality GO:0065008 263 0.045
homeostatic process GO:0042592 142 0.045
positive regulation of cellular catabolic process GO:0031331 3 0.044
pigment granule organization GO:0048753 4 0.044
regulation of cell communication GO:0010646 232 0.043
axonogenesis GO:0007409 152 0.043
positive regulation of cellular biosynthetic process GO:0031328 68 0.043
lateral line system development GO:0048925 76 0.042
positive regulation of transcription dna templated GO:0045893 57 0.042
retinoic acid receptor signaling pathway GO:0048384 16 0.042
polarized epithelial cell differentiation GO:0030859 4 0.041
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.041
intracellular receptor signaling pathway GO:0030522 30 0.041
eye development GO:0001654 277 0.041
myeloid cell homeostasis GO:0002262 56 0.040
cell proliferation GO:0008283 80 0.040
positive regulation of cell adhesion GO:0045785 1 0.040
rhythmic process GO:0048511 21 0.040
gastrulation GO:0007369 208 0.039
eye photoreceptor cell development GO:0042462 30 0.039
lipid metabolic process GO:0006629 52 0.038
taxis GO:0042330 109 0.038
embryonic cranial skeleton morphogenesis GO:0048701 90 0.038
regulation of programmed cell death GO:0043067 101 0.036
bmp signaling pathway GO:0030509 52 0.035
cardiac cell development GO:0055006 21 0.035
protein metabolic process GO:0019538 183 0.034
response to mechanical stimulus GO:0009612 24 0.034
response to hexose GO:0009746 3 0.034
erythrocyte differentiation GO:0030218 54 0.034
negative regulation of bmp signaling pathway GO:0030514 13 0.033
response to endogenous stimulus GO:0009719 83 0.033
telencephalon development GO:0021537 14 0.033
regulation of cellular protein metabolic process GO:0032268 52 0.033
multicellular organism reproduction GO:0032504 35 0.033
regulation of cell death GO:0010941 103 0.033
regionalization GO:0003002 274 0.032
cell division GO:0051301 20 0.032
cellular response to external stimulus GO:0071496 2 0.032
stem cell division GO:0017145 1 0.032
erythrocyte homeostasis GO:0034101 55 0.032
embryonic skeletal system development GO:0048706 97 0.032
response to drug GO:0042493 3 0.032
regulation of cell migration GO:0030334 40 0.031
meiotic nuclear division GO:0007126 4 0.031
stem cell proliferation GO:0072089 4 0.030
carbohydrate homeostasis GO:0033500 1 0.030
multi organism process GO:0051704 134 0.030
somitogenesis GO:0001756 87 0.030
embryonic skeletal system morphogenesis GO:0048704 93 0.030
development of primary female sexual characteristics GO:0046545 4 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.029
programmed cell death GO:0012501 119 0.028
neuron development GO:0048666 262 0.028
response to abiotic stimulus GO:0009628 122 0.028
chemical homeostasis GO:0048878 49 0.028
chemotaxis GO:0006935 104 0.028
androgen metabolic process GO:0008209 2 0.027
endocrine system development GO:0035270 65 0.027
negative regulation of cell growth GO:0030308 7 0.026
septum transversum development GO:0003343 4 0.026
regulation of proteolysis GO:0030162 24 0.026
striated muscle cell development GO:0055002 108 0.026
positive regulation of cell substrate adhesion GO:0010811 1 0.026
regulation of endopeptidase activity GO:0052548 23 0.026
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.025
regulation of apoptotic process GO:0042981 98 0.025
cellular response to biotic stimulus GO:0071216 3 0.025
photoreceptor cell differentiation GO:0046530 55 0.025
positive regulation of nucleic acid templated transcription GO:1903508 57 0.024
positive regulation of neuron apoptotic process GO:0043525 1 0.024
response to ketone GO:1901654 1 0.024
regulation of cell adhesion GO:0030155 15 0.024
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.024
positive regulation of locomotion GO:0040017 14 0.024
cell part morphogenesis GO:0032990 246 0.023
regulation of localization GO:0032879 104 0.023
regulation of cell development GO:0060284 100 0.023
response to glucocorticoid GO:0051384 1 0.023
camp metabolic process GO:0046058 11 0.022
negative regulation of response to stimulus GO:0048585 104 0.022
cytosolic calcium ion transport GO:0060401 3 0.022
cellular protein metabolic process GO:0044267 129 0.022
single organism transport GO:0044765 206 0.022
cellular macromolecular complex assembly GO:0034622 24 0.022
positive regulation of signaling GO:0023056 56 0.022
negative regulation of cell differentiation GO:0045596 46 0.022
pancreas development GO:0031016 84 0.022
positive regulation of neuron projection development GO:0010976 9 0.022
camera type eye development GO:0043010 222 0.022
response to nutrient GO:0007584 3 0.022
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.022
positive regulation of cell cycle GO:0045787 3 0.021
regulation of organ morphogenesis GO:2000027 35 0.021
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.021
mesoderm development GO:0007498 88 0.021
biological adhesion GO:0022610 40 0.020
pectoral fin development GO:0033339 50 0.020
cellular component morphogenesis GO:0032989 336 0.020
neuroblast proliferation GO:0007405 2 0.020
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.020
locomotor rhythm GO:0045475 3 0.020
embryonic viscerocranium morphogenesis GO:0048703 52 0.019
regulation of synapse assembly GO:0051963 3 0.019
regulation of response to external stimulus GO:0032101 31 0.019
lipid storage GO:0019915 1 0.019
regulation of autophagy GO:0010506 3 0.019
dendrite guidance GO:0070983 0 0.019
positive regulation of neuron differentiation GO:0045666 12 0.019
positive regulation of epithelial cell differentiation GO:0030858 2 0.019
response to corticosteroid GO:0031960 1 0.018
small molecule metabolic process GO:0044281 77 0.018
apoptotic process GO:0006915 116 0.018
developmental maturation GO:0021700 34 0.018
positive regulation of cell development GO:0010720 25 0.018
positive regulation of lipase activity GO:0060193 1 0.018
tube morphogenesis GO:0035239 349 0.018
sensory organ development GO:0007423 393 0.018
death GO:0016265 121 0.018
regulation of protein transport GO:0051223 3 0.018
response to organic substance GO:0010033 153 0.018
intracellular estrogen receptor signaling pathway GO:0030520 3 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.017
positive regulation of developmental process GO:0051094 50 0.017
cellular hormone metabolic process GO:0034754 19 0.017
pyruvate metabolic process GO:0006090 1 0.017
reproduction GO:0000003 40 0.017
regulation of cell matrix adhesion GO:0001952 1 0.017
positive regulation of cellular component biogenesis GO:0044089 3 0.017
pancreatic a cell development GO:0003322 2 0.017
locomotory behavior GO:0007626 34 0.017
neuronal action potential GO:0019228 18 0.017
negative regulation of programmed cell death GO:0043069 58 0.017
regulation of cellular component organization GO:0051128 86 0.017
cell projection assembly GO:0030031 64 0.016
positive regulation of neuron death GO:1901216 1 0.016
positive regulation of neurogenesis GO:0050769 24 0.016
positive regulation of mrna splicing via spliceosome GO:0048026 1 0.016
cell migration to the midline involved in heart development GO:0003318 12 0.016
single organism organelle organization GO:1902589 199 0.016
regulation of nervous system development GO:0051960 90 0.016
cell projection morphogenesis GO:0048858 244 0.016
heart jogging GO:0003146 40 0.016
response to steroid hormone GO:0048545 35 0.016
response to inorganic substance GO:0010035 38 0.016
cell cell signaling GO:0007267 52 0.016
negative regulation of axon guidance GO:1902668 1 0.016
regulation of postsynaptic membrane potential GO:0060078 1 0.016
somite development GO:0061053 96 0.016
protein import into nucleus GO:0006606 3 0.016
immune system development GO:0002520 191 0.016
adrenal gland development GO:0030325 10 0.016
phosphate containing compound metabolic process GO:0006796 108 0.015
cardiac muscle fiber development GO:0048739 3 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
calcium ion import GO:0070509 4 0.015
cellular response to drug GO:0035690 1 0.015
inner ear receptor cell fate commitment GO:0060120 4 0.014
myotube cell development GO:0014904 35 0.014
signal transduction GO:0007165 455 0.014
female sex differentiation GO:0046660 4 0.014
cellular carbohydrate metabolic process GO:0044262 4 0.014
cellular lipid metabolic process GO:0044255 36 0.014
segmentation GO:0035282 97 0.014
regulation of cytokine production GO:0001817 3 0.014
lens fiber cell morphogenesis GO:0070309 3 0.014
calcium mediated signaling GO:0019722 2 0.013
regulation of oligodendrocyte differentiation GO:0048713 1 0.013
epithelial tube morphogenesis GO:0060562 148 0.013
cellular response to oxygen levels GO:0071453 1 0.013
negative regulation of growth rate GO:0045967 1 0.013
regulation of dendrite development GO:0050773 3 0.013
negative regulation of growth GO:0045926 10 0.013
proximal distal pattern formation GO:0009954 1 0.013
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.013
positive regulation of translation GO:0045727 1 0.013
viral process GO:0016032 1 0.013
cell proliferation involved in heart morphogenesis GO:0061323 2 0.012
negative regulation of cell communication GO:0010648 96 0.012
regulation of epithelial to mesenchymal transition GO:0010717 3 0.012
feeding behavior GO:0007631 5 0.012
eye photoreceptor cell differentiation GO:0001754 45 0.012
keratinocyte differentiation GO:0030216 0 0.012
blood circulation GO:0008015 87 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
regulation of embryonic development GO:0045995 47 0.012
striated muscle tissue development GO:0014706 110 0.012
regulation of dna templated transcription in response to stress GO:0043620 0 0.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.012
cardiac muscle tissue development GO:0048738 48 0.012
cell maturation GO:0048469 23 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
connective tissue development GO:0061448 99 0.012
sex determination GO:0007530 1 0.012
regulation of mrna splicing via spliceosome GO:0048024 3 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.012
regulation of response to nutrient levels GO:0032107 1 0.012
fin development GO:0033333 77 0.011
regulation of glial cell differentiation GO:0045685 4 0.011
establishment of protein localization to organelle GO:0072594 4 0.011
multicellular organismal response to stress GO:0033555 2 0.011
axon extension GO:0048675 45 0.011
positive regulation of secretion GO:0051047 1 0.011
organonitrogen compound metabolic process GO:1901564 74 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
cellular ketone metabolic process GO:0042180 11 0.011
cellular response to lipid GO:0071396 39 0.011
positive regulation of lipid metabolic process GO:0045834 1 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
cell matrix adhesion GO:0007160 4 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
positive regulation of response to external stimulus GO:0032103 9 0.011
macromolecular complex assembly GO:0065003 35 0.011
anterior posterior pattern specification GO:0009952 152 0.011
positive regulation of mrna metabolic process GO:1903313 2 0.011
urogenital system development GO:0001655 97 0.011
protein maturation GO:0051604 12 0.011
cell proliferation in forebrain GO:0021846 3 0.011
organelle localization GO:0051640 49 0.011
sequestering of calcium ion GO:0051208 3 0.011
nuclear import GO:0051170 3 0.011
response to vitamin GO:0033273 3 0.011
regulation of retinoic acid receptor signaling pathway GO:0048385 5 0.010
regulation of cytoplasmic transport GO:1903649 4 0.010
single organism nuclear import GO:1902593 3 0.010
negative regulation of synapse assembly GO:0051964 2 0.010
cell surface receptor signaling pathway GO:0007166 325 0.010
negative regulation of apoptotic process GO:0043066 55 0.010
regulation of organelle organization GO:0033043 29 0.010
regulation of mesenchymal cell proliferation GO:0010464 1 0.010
carbohydrate metabolic process GO:0005975 12 0.010
mechanosensory behavior GO:0007638 2 0.010
organelle organization GO:0006996 227 0.010
lens fiber cell development GO:0070307 3 0.010
regulation of cysteine type endopeptidase activity GO:2000116 21 0.010
neuron projection regeneration GO:0031102 16 0.010
establishment of localization in cell GO:0051649 77 0.010
cation transport GO:0006812 81 0.010

pbx1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.018