Danio rerio

0 known processes

pcbd1

6-pyruvoyl-tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1)

(Aliases: MGC73389,zgc:73389,pcbd)

pcbd1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
alpha amino acid metabolic process GO:1901605 3 0.188
larval development GO:0002164 2 0.142
cellular modified amino acid metabolic process GO:0006575 3 0.119
organic acid metabolic process GO:0006082 31 0.100
organonitrogen compound metabolic process GO:1901564 74 0.091
cellular amino acid metabolic process GO:0006520 7 0.079
adult behavior GO:0030534 2 0.069
negative regulation of biological process GO:0048519 304 0.069
aging GO:0007568 2 0.066
regulation of multicellular organism growth GO:0040014 4 0.065
oxoacid metabolic process GO:0043436 31 0.062
single organism metabolic process GO:0044710 217 0.057
Mouse
small molecule catabolic process GO:0044282 3 0.054
cellular component movement GO:0006928 335 0.053
nitrogen compound metabolic process GO:0006807 319 0.050
carboxylic acid catabolic process GO:0046395 3 0.048
response to chemical GO:0042221 320 0.046
cellular nitrogen compound metabolic process GO:0034641 290 0.046
regulation of biological quality GO:0065008 263 0.046
blood vessel development GO:0001568 246 0.045
axon development GO:0061564 166 0.044
carboxylic acid metabolic process GO:0019752 22 0.044
energy reserve metabolic process GO:0006112 2 0.044
cellular ketone metabolic process GO:0042180 11 0.040
cellular carbohydrate metabolic process GO:0044262 4 0.039
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.039
cellular nitrogen compound biosynthetic process GO:0044271 218 0.037
developmental growth GO:0048589 166 0.037
response to external stimulus GO:0009605 264 0.037
organelle fusion GO:0048284 3 0.035
regulation of carbohydrate metabolic process GO:0006109 4 0.034
fatty acid beta oxidation GO:0006635 1 0.034
cell death GO:0008219 121 0.034
regulation of fatty acid metabolic process GO:0019217 1 0.033
eye development GO:0001654 277 0.032
organic acid catabolic process GO:0016054 3 0.031
immune system process GO:0002376 241 0.031
small molecule metabolic process GO:0044281 77 0.030
single organism membrane fusion GO:0044801 2 0.030
organic substance biosynthetic process GO:1901576 289 0.030
positive regulation of transport GO:0051050 2 0.030
carbohydrate biosynthetic process GO:0016051 1 0.030
embryo development ending in birth or egg hatching GO:0009792 271 0.030
multicellular organism growth GO:0035264 4 0.030
biosynthetic process GO:0009058 294 0.029
maintenance of location GO:0051235 4 0.029
positive regulation of cellular catabolic process GO:0031331 3 0.028
regulation of cellular ketone metabolic process GO:0010565 7 0.027
localization of cell GO:0051674 244 0.027
organic cyclic compound metabolic process GO:1901360 301 0.027
regulation of cell shape GO:0008360 1 0.027
neuron development GO:0048666 262 0.027
guanosine containing compound metabolic process GO:1901068 4 0.027
regulation of synapse organization GO:0050807 3 0.026
regulation of reproductive process GO:2000241 4 0.026
i kappab kinase nf kappab signaling GO:0007249 4 0.026
transcription dna templated GO:0006351 181 0.026
regulation of cell death GO:0010941 103 0.025
lipid storage GO:0019915 1 0.025
cellular amine metabolic process GO:0044106 2 0.025
regulation of synapse assembly GO:0051963 3 0.024
regulation of cellular biosynthetic process GO:0031326 245 0.024
nucleic acid metabolic process GO:0090304 244 0.024
regulation of biosynthetic process GO:0009889 250 0.024
protein localization to plasma membrane GO:0072659 1 0.023
establishment of localization GO:0051234 244 0.023
heterocycle biosynthetic process GO:0018130 215 0.023
regulation of establishment of protein localization GO:0070201 4 0.023
cellular macromolecule metabolic process GO:0044260 391 0.023
membrane fusion GO:0061025 2 0.023
negative regulation of protein kinase activity GO:0006469 4 0.023
cell projection organization GO:0030030 284 0.023
response to glucocorticoid GO:0051384 1 0.023
negative regulation of cellular process GO:0048523 283 0.023
cellular lipid catabolic process GO:0044242 3 0.023
apoptotic process GO:0006915 116 0.022
nucleobase containing compound biosynthetic process GO:0034654 205 0.022
nucleobase containing compound metabolic process GO:0006139 274 0.022
regulation of multicellular organismal process GO:0051239 277 0.022
macromolecule biosynthetic process GO:0009059 227 0.022
negative regulation of synapse assembly GO:0051964 2 0.022
amine metabolic process GO:0009308 2 0.022
regulation of metabolic process GO:0019222 359 0.022
cell morphogenesis GO:0000902 289 0.022
regulation of primary metabolic process GO:0080090 311 0.021
sensory organ development GO:0007423 393 0.021
single organism biosynthetic process GO:0044711 71 0.021
striated muscle cell differentiation GO:0051146 129 0.021
single organism transport GO:0044765 206 0.021
positive regulation of catabolic process GO:0009896 4 0.021
regulation of cell activation GO:0050865 1 0.021
peptidyl serine modification GO:0018209 2 0.021
cell motility GO:0048870 244 0.020
response to hormone GO:0009725 48 0.020
positive regulation of cellular amine metabolic process GO:0033240 0 0.020
wound healing GO:0042060 90 0.020
locomotion GO:0040011 313 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
organelle organization GO:0006996 227 0.020
gtp metabolic process GO:0046039 4 0.020
positive regulation of biological process GO:0048518 253 0.020
response to corticosteroid GO:0031960 1 0.020
negative regulation of multicellular organismal process GO:0051241 69 0.020
death GO:0016265 121 0.020
cellular macromolecule biosynthetic process GO:0034645 224 0.019
neuroblast proliferation GO:0007405 2 0.019
gene expression GO:0010467 252 0.019
regulation of protein transport GO:0051223 3 0.019
fatty acid transport GO:0015908 1 0.019
phagocytosis GO:0006909 3 0.019
camera type eye development GO:0043010 222 0.019
cellular response to external stimulus GO:0071496 2 0.019
lipid catabolic process GO:0016042 4 0.019
signal transduction GO:0007165 455 0.019
digestive tract mesoderm development GO:0007502 1 0.019
neuron differentiation GO:0030182 353 0.019
response to drug GO:0042493 3 0.019
ion transmembrane transport GO:0034220 91 0.018
lipid oxidation GO:0034440 1 0.018
central nervous system development GO:0007417 387 0.018
taurine metabolic process GO:0019530 1 0.018
aromatic compound biosynthetic process GO:0019438 217 0.018
cellular biosynthetic process GO:0044249 286 0.017
gtp catabolic process GO:0006184 2 0.017
cellular response to chemical stimulus GO:0070887 157 0.017
nucleic acid templated transcription GO:0097659 181 0.017
cell migration GO:0016477 237 0.017
blood vessel morphogenesis GO:0048514 216 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
extrinsic apoptotic signaling pathway GO:0097191 3 0.017
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.017
response to stress GO:0006950 263 0.017
response to glucose GO:0009749 3 0.017
vasculature development GO:0001944 278 0.017
response to nutrient GO:0007584 3 0.017
negative regulation of protein phosphorylation GO:0001933 4 0.016
regulation of dendrite development GO:0050773 3 0.016
actin filament based movement GO:0030048 1 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
heterocycle metabolic process GO:0046483 290 0.016
positive regulation of nucleoside metabolic process GO:0045979 1 0.016
regulation of apoptotic process GO:0042981 98 0.016
cellular amino acid biosynthetic process GO:0008652 2 0.016
regulation of protein targeting GO:1903533 2 0.016
regulation of response to stimulus GO:0048583 269 0.016
cellular catabolic process GO:0044248 27 0.016
cell morphogenesis involved in differentiation GO:0000904 195 0.015
negative regulation of kinase activity GO:0033673 4 0.015
rna 3 end processing GO:0031123 2 0.015
cellular aromatic compound metabolic process GO:0006725 295 0.015
fatty acid oxidation GO:0019395 1 0.015
negative regulation of macromolecule metabolic process GO:0010605 76 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
programmed cell death GO:0012501 119 0.015
hydrogen peroxide metabolic process GO:0042743 2 0.015
superoxide metabolic process GO:0006801 2 0.015
alcohol biosynthetic process GO:0046165 2 0.015
regulation of sodium ion transport GO:0002028 2 0.015
apoptotic process involved in development GO:1902742 2 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
inositol lipid mediated signaling GO:0048017 2 0.014
response to endogenous stimulus GO:0009719 83 0.014
regulation of glucose transport GO:0010827 1 0.014
regulation of nucleotide catabolic process GO:0030811 2 0.014
regulation of carbohydrate biosynthetic process GO:0043255 1 0.014
cellular localization GO:0051641 97 0.014
regulation of gene expression GO:0010468 265 0.014
monocarboxylic acid catabolic process GO:0072329 3 0.014
single organism nuclear import GO:1902593 3 0.014
purine nucleoside monophosphate catabolic process GO:0009128 4 0.014
cellular response to oxygen radical GO:0071450 2 0.014
cellular component morphogenesis GO:0032989 336 0.014
response to abiotic stimulus GO:0009628 122 0.014
glial cell migration GO:0008347 3 0.014
rna metabolic process GO:0016070 219 0.013
hepaticobiliary system development GO:0061008 98 0.013
oxidation reduction process GO:0055114 41 0.013
Mouse
growth GO:0040007 174 0.013
taxis GO:0042330 109 0.013
regulation of multicellular organismal development GO:2000026 223 0.013
chordate embryonic development GO:0043009 271 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
homeostatic process GO:0042592 142 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.013
ribonucleoside monophosphate catabolic process GO:0009158 4 0.013
fatty acid catabolic process GO:0009062 1 0.013
protein metabolic process GO:0019538 183 0.013
protein targeting to nucleus GO:0044744 3 0.013
single organism organelle organization GO:1902589 199 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
synaptic growth at neuromuscular junction GO:0051124 2 0.012
response to hydrogen peroxide GO:0042542 3 0.012
autophagy GO:0006914 4 0.012
regeneration GO:0031099 91 0.012
dicarboxylic acid metabolic process GO:0043648 1 0.012
rna biosynthetic process GO:0032774 181 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
muscle cell differentiation GO:0042692 139 0.012
regulation of programmed cell death GO:0043067 101 0.012
protein import GO:0017038 3 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
multicellular organismal metabolic process GO:0044236 2 0.012
regulation of protein import into nucleus GO:0042306 2 0.012
protein localization to nucleus GO:0034504 3 0.012
cell substrate adhesion GO:0031589 4 0.012
response to inorganic substance GO:0010035 38 0.012
response to alkaloid GO:0043279 2 0.012
organic cyclic compound biosynthetic process GO:1901362 223 0.012
ameboidal type cell migration GO:0001667 143 0.012
angiogenesis GO:0001525 158 0.012
negative chemotaxis GO:0050919 1 0.012
regulation of inflammatory response GO:0050727 2 0.012
regulation of gtpase activity GO:0043087 2 0.012
positive regulation of cell cycle GO:0045787 3 0.012
nuclear migration GO:0007097 3 0.012
mononuclear cell proliferation GO:0032943 1 0.012
cellular response to nutrient levels GO:0031669 2 0.012
regulation of signal transduction GO:0009966 225 0.012
melanin metabolic process GO:0006582 2 0.012
response to monosaccharide GO:0034284 3 0.012
response to hexose GO:0009746 3 0.012
lymphocyte proliferation GO:0046651 1 0.011
regulation of blood vessel size GO:0050880 2 0.011
regulation of wound healing GO:0061041 2 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
regulation of cell differentiation GO:0045595 142 0.011
g1 s transition of mitotic cell cycle GO:0000082 1 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.011
heart development GO:0007507 313 0.011
s adenosylmethionine metabolic process GO:0046500 1 0.011
inorganic ion transmembrane transport GO:0098660 57 0.011
regulation of developmental process GO:0050793 247 0.011
monovalent inorganic cation transport GO:0015672 42 0.011
negative regulation of programmed cell death GO:0043069 58 0.011
morphogenesis of an epithelium GO:0002009 333 0.011
single organism localization GO:1902578 225 0.011
regulation of dna replication GO:0006275 3 0.011
regulation of transcription dna templated GO:0006355 213 0.011
positive regulation of lipid metabolic process GO:0045834 1 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
adherens junction maintenance GO:0034334 2 0.011
gland development GO:0048732 143 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
cellular component biogenesis GO:0044085 178 0.011
Mouse
response to superoxide GO:0000303 2 0.011
cellular response to endogenous stimulus GO:0071495 68 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
nuclear import GO:0051170 3 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
regulation of metal ion transport GO:0010959 4 0.011
organelle localization GO:0051640 49 0.011
transport GO:0006810 220 0.011
regulation of nitrogen compound metabolic process GO:0051171 251 0.011
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.010
negative regulation of cell death GO:0060548 60 0.010
cellular protein metabolic process GO:0044267 129 0.010
response to other organism GO:0051707 97 0.010
negative regulation of metabolic process GO:0009892 86 0.010
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.010
regulation of filopodium assembly GO:0051489 2 0.010
axonogenesis GO:0007409 152 0.010
response to lipid GO:0033993 60 0.010
multicellular organismal response to stress GO:0033555 2 0.010
cellular response to extracellular stimulus GO:0031668 2 0.010
response to organic substance GO:0010033 153 0.010
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.010
cellular response to oxygen levels GO:0071453 1 0.010
cofactor metabolic process GO:0051186 15 0.010
response to wounding GO:0009611 116 0.010
negative regulation of leukocyte differentiation GO:1902106 1 0.010

pcbd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.051
inherited metabolic disorder DOID:655 0 0.046
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.013
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
musculoskeletal system disease DOID:17 0 0.011
lipid metabolism disorder DOID:3146 0 0.011