Danio rerio

0 known processes

pck2

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

(Aliases: zgc:77867,pck,id:ibd5157)

pck2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intestinal absorption GO:0050892 2 0.316
axon development GO:0061564 166 0.229
chordate embryonic development GO:0043009 271 0.220
axonogenesis GO:0007409 152 0.220
cell morphogenesis involved in differentiation GO:0000904 195 0.217
head development GO:0060322 303 0.205
biosynthetic process GO:0009058 294 0.187
generation of neurons GO:0048699 385 0.184
neuron projection morphogenesis GO:0048812 161 0.184
response to external stimulus GO:0009605 264 0.170
brain development GO:0007420 293 0.162
alcohol biosynthetic process GO:0046165 2 0.150
single organism metabolic process GO:0044710 217 0.149
neuron differentiation GO:0030182 353 0.143
response to glucose GO:0009749 3 0.133
Zebrafish
carboxylic acid catabolic process GO:0046395 3 0.132
cellular response to lipid GO:0071396 39 0.132
central nervous system development GO:0007417 387 0.131
embryonic organ morphogenesis GO:0048562 274 0.124
locomotion GO:0040011 313 0.123
cellular response to estrogen stimulus GO:0071391 24 0.118
response to nutrient GO:0007584 3 0.116
response to organic substance GO:0010033 153 0.110
Zebrafish
camera type eye development GO:0043010 222 0.110
cellular carbohydrate metabolic process GO:0044262 4 0.108
lipid storage GO:0019915 1 0.105
Worm
small molecule metabolic process GO:0044281 77 0.104
cellular response to organic cyclic compound GO:0071407 38 0.103
cell part morphogenesis GO:0032990 246 0.099
localization of cell GO:0051674 244 0.098
single organism localization GO:1902578 225 0.087
hindbrain development GO:0030902 91 0.085
neural crest cell development GO:0014032 62 0.084
single organism transport GO:0044765 206 0.083
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.080
oxidation reduction process GO:0055114 41 0.079
response to chemical GO:0042221 320 0.079
Zebrafish
lipid homeostasis GO:0055088 3 0.078
cellular response to steroid hormone stimulus GO:0071383 31 0.077
aging GO:0007568 2 0.070
chemical homeostasis GO:0048878 49 0.070
regulation of cell death GO:0010941 103 0.069
sensory organ morphogenesis GO:0090596 200 0.068
response to carbohydrate GO:0009743 3 0.068
Zebrafish
regulation of synapse assembly GO:0051963 3 0.068
response to vitamin b3 GO:0033552 2 0.067
energy reserve metabolic process GO:0006112 2 0.064
cellular component movement GO:0006928 335 0.064
cellular component morphogenesis GO:0032989 336 0.064
establishment of localization GO:0051234 244 0.063
cell motility GO:0048870 244 0.062
response to monosaccharide GO:0034284 3 0.062
Zebrafish
maintenance of location GO:0051235 4 0.059
Worm
transport GO:0006810 220 0.059
cellular biosynthetic process GO:0044249 286 0.058
cell projection morphogenesis GO:0048858 244 0.057
regulation of metabolic process GO:0019222 359 0.056
skeletal system development GO:0001501 181 0.056
epithelial cell differentiation GO:0030855 116 0.055
neuron projection development GO:0031175 180 0.055
phagocytosis GO:0006909 3 0.055
response to oxygen containing compound GO:1901700 55 0.053
Zebrafish
synaptic growth at neuromuscular junction GO:0051124 2 0.052
response to xenobiotic stimulus GO:0009410 45 0.051
cellular response to chemical stimulus GO:0070887 157 0.051
gtp metabolic process GO:0046039 4 0.051
morphogenesis of an epithelium GO:0002009 333 0.050
eye development GO:0001654 277 0.049
adult behavior GO:0030534 2 0.049
vasculature development GO:0001944 278 0.048
intestinal cholesterol absorption GO:0030299 2 0.048
cell surface receptor signaling pathway GO:0007166 325 0.047
response to organic cyclic compound GO:0014070 51 0.047
gene expression GO:0010467 252 0.046
regulation of localization GO:0032879 104 0.046
stem cell maintenance GO:0019827 4 0.046
glucose homeostasis GO:0042593 1 0.045
guanosine containing compound metabolic process GO:1901068 4 0.045
acylglycerol homeostasis GO:0055090 2 0.045
negative regulation of biological process GO:0048519 304 0.044
response to vitamin GO:0033273 3 0.044
regulation of stem cell differentiation GO:2000736 4 0.044
amine metabolic process GO:0009308 2 0.043
cellular response to endogenous stimulus GO:0071495 68 0.043
taxis GO:0042330 109 0.042
connective tissue development GO:0061448 99 0.042
cellular amine metabolic process GO:0044106 2 0.042
cellular amino acid metabolic process GO:0006520 7 0.041
organic substance transport GO:0071702 58 0.041
cellular nitrogen compound metabolic process GO:0034641 290 0.041
positive regulation of biological process GO:0048518 253 0.040
embryo development ending in birth or egg hatching GO:0009792 271 0.040
skeletal system morphogenesis GO:0048705 102 0.039
regulation of gene expression GO:0010468 265 0.039
osteoclast differentiation GO:0030316 1 0.039
regulation of macromolecule metabolic process GO:0060255 317 0.038
cellular response to external stimulus GO:0071496 2 0.038
response to steroid hormone GO:0048545 35 0.037
alpha amino acid metabolic process GO:1901605 3 0.037
sensory organ development GO:0007423 393 0.037
phosphorus metabolic process GO:0006793 109 0.037
organic cyclic compound metabolic process GO:1901360 301 0.037
fin development GO:0033333 77 0.037
cellular response to hormone stimulus GO:0032870 39 0.035
response to lipid GO:0033993 60 0.035
regulation of multicellular organismal process GO:0051239 277 0.035
organic acid metabolic process GO:0006082 31 0.035
organic substance biosynthetic process GO:1901576 289 0.034
response to stress GO:0006950 263 0.034
oxoacid metabolic process GO:0043436 31 0.033
regulation of cell projection assembly GO:0060491 4 0.033
small molecule catabolic process GO:0044282 3 0.033
energy derivation by oxidation of organic compounds GO:0015980 5 0.033
nitrogen compound metabolic process GO:0006807 319 0.033
regulation of cellular amine metabolic process GO:0033238 0 0.033
transition metal ion transport GO:0000041 6 0.032
cell morphogenesis GO:0000902 289 0.032
phenol containing compound biosynthetic process GO:0046189 4 0.032
positive regulation of cellular process GO:0048522 201 0.032
regulation of cytokine production GO:0001817 3 0.032
cellular biogenic amine metabolic process GO:0006576 2 0.031
cellular transition metal ion homeostasis GO:0046916 3 0.031
neuron development GO:0048666 262 0.031
regulation of primary metabolic process GO:0080090 311 0.031
regulation of biological quality GO:0065008 263 0.031
Worm
cellular lipid catabolic process GO:0044242 3 0.031
embryonic organ development GO:0048568 381 0.030
positive regulation of cellular component biogenesis GO:0044089 3 0.030
tube morphogenesis GO:0035239 349 0.030
cell projection organization GO:0030030 284 0.030
cellular response to organic substance GO:0071310 105 0.029
hormone transport GO:0009914 2 0.029
stem cell development GO:0048864 82 0.029
post embryonic organ development GO:0048569 4 0.028
negative regulation of map kinase activity GO:0043407 2 0.028
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.028
mitochondrial transport GO:0006839 2 0.028
phosphate containing compound metabolic process GO:0006796 108 0.028
hormone biosynthetic process GO:0042446 3 0.028
regulation of epithelial cell proliferation GO:0050678 3 0.027
defense response to fungus GO:0050832 2 0.027
regulation of hormone secretion GO:0046883 2 0.027
organonitrogen compound biosynthetic process GO:1901566 47 0.027
cell death GO:0008219 121 0.027
cartilage development GO:0051216 96 0.027
response to amino acid GO:0043200 2 0.027
guanosine containing compound catabolic process GO:1901069 2 0.027
regulation of signaling GO:0023051 235 0.027
water homeostasis GO:0030104 4 0.027
hormone secretion GO:0046879 2 0.026
cell migration GO:0016477 237 0.026
pectoral fin development GO:0033339 50 0.026
camera type eye morphogenesis GO:0048593 108 0.026
chemotaxis GO:0006935 104 0.026
long chain fatty acid transport GO:0015909 1 0.026
neural crest cell differentiation GO:0014033 72 0.026
catabolic process GO:0009056 32 0.026
central nervous system neuron differentiation GO:0021953 74 0.026
cellular aldehyde metabolic process GO:0006081 4 0.026
regulation of response to oxidative stress GO:1902882 2 0.025
lipid catabolic process GO:0016042 4 0.025
heterocycle metabolic process GO:0046483 290 0.025
multi organism process GO:0051704 134 0.025
catecholamine metabolic process GO:0006584 2 0.025
single organism biosynthetic process GO:0044711 71 0.025
interspecies interaction between organisms GO:0044419 4 0.025
epithelial tube morphogenesis GO:0060562 148 0.025
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.025
cellular aromatic compound metabolic process GO:0006725 295 0.024
regulation of response to stress GO:0080134 36 0.024
heart development GO:0007507 313 0.024
negative regulation of synapse assembly GO:0051964 2 0.024
ion transport GO:0006811 114 0.024
cellular response to fatty acid GO:0071398 3 0.024
cellular response to xenobiotic stimulus GO:0071466 35 0.024
apoptotic process GO:0006915 116 0.024
cellular response to prostaglandin stimulus GO:0071379 3 0.024
carbohydrate metabolic process GO:0005975 12 0.024
negative regulation of cytokine production GO:0001818 1 0.024
carboxylic acid metabolic process GO:0019752 22 0.024
nucleobase containing compound metabolic process GO:0006139 274 0.023
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.023
oxalate transport GO:0019532 1 0.023
programmed cell death GO:0012501 119 0.023
mesenchyme development GO:0060485 127 0.022
regulation of synapse organization GO:0050807 3 0.022
fat soluble vitamin metabolic process GO:0006775 4 0.022
organic hydroxy compound metabolic process GO:1901615 16 0.022
cellular macromolecule metabolic process GO:0044260 391 0.022
cellular response to biotic stimulus GO:0071216 3 0.022
mesenchymal cell development GO:0014031 78 0.022
carbohydrate biosynthetic process GO:0016051 1 0.022
homeostatic process GO:0042592 142 0.021
death GO:0016265 121 0.021
organic acid catabolic process GO:0016054 3 0.021
immune system process GO:0002376 241 0.021
actin filament based movement GO:0030048 1 0.021
carbohydrate homeostasis GO:0033500 1 0.021
establishment of blood brain barrier GO:0060856 2 0.021
regulation of signal transduction GO:0009966 225 0.021
positive regulation of cytoskeleton organization GO:0051495 3 0.021
catechol containing compound biosynthetic process GO:0009713 2 0.021
lateral line system development GO:0048925 76 0.021
hemopoiesis GO:0030097 183 0.021
heart morphogenesis GO:0003007 156 0.021
positive regulation of transport GO:0051050 2 0.021
regulation of cellular metabolic process GO:0031323 320 0.020
gland development GO:0048732 143 0.020
cell death in response to oxidative stress GO:0036473 2 0.020
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.020
striated muscle cell development GO:0055002 108 0.020
cellular response to lipopolysaccharide GO:0071222 3 0.020
negative regulation of protein kinase activity GO:0006469 4 0.020
response to fatty acid GO:0070542 5 0.019
regulation of jun kinase activity GO:0043506 3 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
membrane invagination GO:0010324 1 0.019
cellular response to extracellular stimulus GO:0031668 2 0.019
organophosphate metabolic process GO:0019637 37 0.019
embryonic skeletal system development GO:0048706 97 0.019
positive regulation of cellular catabolic process GO:0031331 3 0.019
organonitrogen compound metabolic process GO:1901564 74 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.019
positive regulation of metabolic process GO:0009893 108 0.019
response to ketone GO:1901654 1 0.019
regulation of binding GO:0051098 3 0.018
leukocyte mediated cytotoxicity GO:0001909 1 0.018
meiotic nuclear division GO:0007126 4 0.018
growth GO:0040007 174 0.018
regulation of system process GO:0044057 40 0.018
regulation of apoptotic process GO:0042981 98 0.018
cellular response to molecule of bacterial origin GO:0071219 3 0.018
anion homeostasis GO:0055081 9 0.018
regulation of membrane potential GO:0042391 23 0.018
cellular response to decreased oxygen levels GO:0036294 1 0.018
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.018
negative regulation of defense response GO:0031348 2 0.018
determination of bilateral symmetry GO:0009855 204 0.018
response to hexose GO:0009746 3 0.017
Zebrafish
fin morphogenesis GO:0033334 53 0.017
diterpenoid metabolic process GO:0016101 15 0.017
innate immune response GO:0045087 13 0.017
regulation of cell communication GO:0010646 232 0.017
regulation of response to stimulus GO:0048583 269 0.017
negative regulation of cellular process GO:0048523 283 0.017
multicellular organism growth GO:0035264 4 0.017
rna metabolic process GO:0016070 219 0.017
retina development in camera type eye GO:0060041 146 0.017
transcription from rna polymerase ii promoter GO:0006366 80 0.017
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.017
determination of left right symmetry GO:0007368 179 0.017
neutrophil migration GO:1990266 10 0.017
gtp catabolic process GO:0006184 2 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.017
organic hydroxy compound biosynthetic process GO:1901617 6 0.017
circulatory system process GO:0003013 87 0.017
response to hormone GO:0009725 48 0.017
multicellular organismal response to stress GO:0033555 2 0.017
female gonad development GO:0008585 4 0.017
hormone metabolic process GO:0042445 19 0.017
cellular lipid metabolic process GO:0044255 36 0.017
long chain fatty acid metabolic process GO:0001676 1 0.017
glycerophospholipid biosynthetic process GO:0046474 1 0.017
specification of symmetry GO:0009799 204 0.017
fatty acid transport GO:0015908 1 0.017
lymphatic endothelial cell differentiation GO:0060836 1 0.017
tissue remodeling GO:0048771 4 0.016
response to hydrogen peroxide GO:0042542 3 0.016
response to endogenous stimulus GO:0009719 83 0.016
somite development GO:0061053 96 0.016
embryonic heart tube development GO:0035050 133 0.016
determination of heart left right asymmetry GO:0061371 117 0.016
transmembrane transport GO:0055085 120 0.016
segmentation GO:0035282 97 0.016
wound healing GO:0042060 90 0.016
negative regulation of epithelial cell proliferation GO:0050680 1 0.016
developmental growth GO:0048589 166 0.016
internal peptidyl lysine acetylation GO:0018393 2 0.016
stem cell differentiation GO:0048863 117 0.016
regulation of cell activation GO:0050865 1 0.016
secondary metabolic process GO:0019748 3 0.015
negative regulation of heart contraction GO:0045822 2 0.015
regulation of metal ion transport GO:0010959 4 0.015
ion homeostasis GO:0050801 41 0.015
regulation of protein complex assembly GO:0043254 3 0.015
peptide transport GO:0015833 1 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
regulation of cholesterol transport GO:0032374 3 0.015
dopamine metabolic process GO:0042417 2 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.015
regulation of carbohydrate metabolic process GO:0006109 4 0.015
larval development GO:0002164 2 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
iron ion transmembrane transport GO:0034755 3 0.015
protein polymerization GO:0051258 4 0.015
lipid digestion GO:0044241 3 0.015
heart contraction GO:0060047 71 0.015
peptidyl lysine acetylation GO:0018394 2 0.015
estrogen metabolic process GO:0008210 2 0.015
signal transduction GO:0007165 455 0.015
antimicrobial humoral response GO:0019730 2 0.015
iron ion transport GO:0006826 4 0.014
regionalization GO:0003002 274 0.014
hematopoietic progenitor cell differentiation GO:0002244 23 0.014
response to estrogen GO:0043627 27 0.014
extrinsic apoptotic signaling pathway GO:0097191 3 0.014
negative regulation of kinase activity GO:0033673 4 0.014
response to fungus GO:0009620 25 0.014
cellular response to oxygen levels GO:0071453 1 0.014
negative regulation of stem cell differentiation GO:2000737 2 0.014
cation transport GO:0006812 81 0.014
regulation of oxidative stress induced cell death GO:1903201 2 0.014
regulation of hormone levels GO:0010817 21 0.014
regulation of inflammatory response GO:0050727 2 0.014
reproductive process GO:0022414 40 0.014
protein metabolic process GO:0019538 183 0.014
cellular hormone metabolic process GO:0034754 19 0.014
retinoid metabolic process GO:0001523 15 0.014
pectoral fin morphogenesis GO:0035138 29 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
forebrain development GO:0030900 96 0.014
heart process GO:0003015 71 0.014
response to acid chemical GO:0001101 17 0.014
regulation of cellular response to oxidative stress GO:1900407 2 0.014
embryonic skeletal system morphogenesis GO:0048704 93 0.013
carbohydrate derivative metabolic process GO:1901135 61 0.013
regulation of lipid transport GO:0032368 4 0.013
cardiac cell fate commitment GO:0060911 1 0.013
pyruvate metabolic process GO:0006090 1 0.013
dopamine biosynthetic process GO:0042416 2 0.013
lipid metabolic process GO:0006629 52 0.013
transcription dna templated GO:0006351 181 0.013
liver development GO:0001889 96 0.013
single organism carbohydrate metabolic process GO:0044723 12 0.013
axon ensheathment in central nervous system GO:0032291 2 0.013
macromolecule biosynthetic process GO:0009059 227 0.013
muscle cell differentiation GO:0042692 139 0.013
proepicardium development GO:0003342 4 0.013
regulation of fatty acid metabolic process GO:0019217 1 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
central nervous system neuron development GO:0021954 29 0.013
regulation of cellular biosynthetic process GO:0031326 245 0.013
regulation of muscle contraction GO:0006937 3 0.013
intracellular signal transduction GO:0035556 85 0.013
positive regulation of catabolic process GO:0009896 4 0.013
female sex differentiation GO:0046660 4 0.013
regulation of hemostasis GO:1900046 1 0.013
epithalamus development GO:0021538 10 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
cellular chemical homeostasis GO:0055082 17 0.013
positive regulation of transcription dna templated GO:0045893 57 0.013
sequestering of metal ion GO:0051238 3 0.013
cellular ketone metabolic process GO:0042180 11 0.013
neurotransmitter transport GO:0006836 2 0.013
regulation of nitrogen compound metabolic process GO:0051171 251 0.013
endothelial cell fate commitment GO:0060839 3 0.013
positive regulation of protein complex assembly GO:0031334 2 0.012
response to transition metal nanoparticle GO:1990267 28 0.012
fatty acid oxidation GO:0019395 1 0.012
embryonic heart tube morphogenesis GO:0003143 108 0.012
regulation of macromolecule biosynthetic process GO:0010556 225 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
response to copper ion GO:0046688 13 0.012
regulation of tube size GO:0035150 2 0.012
cardiocyte differentiation GO:0035051 44 0.012
response to alkaloid GO:0043279 2 0.012
negative regulation of response to stimulus GO:0048585 104 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
tube closure GO:0060606 1 0.012
nucleic acid metabolic process GO:0090304 244 0.012
aromatic compound biosynthetic process GO:0019438 217 0.012
neutrophil chemotaxis GO:0030593 10 0.012
inner ear morphogenesis GO:0042472 63 0.012
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.012
organic cyclic compound biosynthetic process GO:1901362 223 0.012
regulation of transcription dna templated GO:0006355 213 0.012
regulation of blood vessel size GO:0050880 2 0.012
system process GO:0003008 185 0.012
xenobiotic metabolic process GO:0006805 4 0.012
positive regulation of secretion GO:0051047 1 0.012
positive regulation of stress activated mapk cascade GO:0032874 3 0.012
regulation of heart rate GO:0002027 5 0.012
respiratory burst GO:0045730 2 0.012
triglyceride homeostasis GO:0070328 2 0.011
mesoderm development GO:0007498 88 0.011
single organism nuclear import GO:1902593 3 0.011
catechol containing compound metabolic process GO:0009712 2 0.011
regulation of gtpase activity GO:0043087 2 0.011
organophosphate biosynthetic process GO:0090407 23 0.011
toll like receptor signaling pathway GO:0002224 4 0.011
phagocytosis engulfment GO:0006911 1 0.011
appendage morphogenesis GO:0035107 56 0.011
somitogenesis GO:0001756 87 0.011
protein import GO:0017038 3 0.011
regulation of biosynthetic process GO:0009889 250 0.011
establishment of epithelial cell polarity GO:0090162 2 0.011
nuclear transport GO:0051169 4 0.011
catecholamine biosynthetic process GO:0042423 2 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
regeneration GO:0031099 91 0.011
mesenchymal cell differentiation GO:0048762 87 0.011
autophagy GO:0006914 4 0.011
cellular protein modification process GO:0006464 100 0.011
negative regulation of signal transduction GO:0009968 94 0.011
pyrimidine containing compound metabolic process GO:0072527 3 0.010
hematopoietic or lymphoid organ development GO:0048534 191 0.010
nerve development GO:0021675 45 0.010
appendage development GO:0048736 80 0.010
blood vessel development GO:0001568 246 0.010
pigmentation GO:0043473 85 0.010
retinal metabolic process GO:0042574 3 0.010
electron transport chain GO:0022900 2 0.010
heart looping GO:0001947 94 0.010
anterior posterior pattern specification GO:0009952 152 0.010
positive regulation of nucleoside metabolic process GO:0045979 1 0.010
positive regulation of jun kinase activity GO:0043507 2 0.010
eye morphogenesis GO:0048592 144 0.010
establishment of localization in cell GO:0051649 77 0.010
cellular homeostasis GO:0019725 26 0.010
primary neural tube formation GO:0014020 1 0.010
organic substance catabolic process GO:1901575 28 0.010
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.010
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.010
multi organism cellular process GO:0044764 2 0.010

pck2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.067
inherited metabolic disorder DOID:655 0 0.067
nervous system disease DOID:863 0 0.026
disease of anatomical entity DOID:7 0 0.026
eye disease DOID:5614 0 0.021
sensory system disease DOID:0050155 0 0.021
eye and adnexa disease DOID:1492 0 0.021
brain disease DOID:936 0 0.011
central nervous system disease DOID:331 0 0.011