Danio rerio

9 known processes

pcna

proliferating cell nuclear antigen

(Aliases: cb16,wu:fa28e03,fb36g03,wu:fb36g03)

pcna biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromosome organization GO:0051276 31 0.997
regulation of nitrogen compound metabolic process GO:0051171 251 0.989
Human Mouse
heterocycle biosynthetic process GO:0018130 215 0.983
Human Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.978
Human Mouse Fly
macromolecule biosynthetic process GO:0009059 227 0.978
Human Mouse Fly
nucleic acid metabolic process GO:0090304 244 0.976
Human Mouse Fly
biosynthetic process GO:0009058 294 0.976
Human Mouse Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.971
Human Mouse Fly
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.969
Human Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.961
Human
hematopoietic or lymphoid organ development GO:0048534 191 0.960
nucleobase containing compound metabolic process GO:0006139 274 0.945
Human Mouse Fly
regulation of cellular metabolic process GO:0031323 320 0.941
Human Mouse
organic cyclic compound metabolic process GO:1901360 301 0.936
Human Mouse Fly
cellular macromolecule metabolic process GO:0044260 391 0.930
Human Mouse Fly
organic substance biosynthetic process GO:1901576 289 0.930
Human Mouse Fly
nucleobase containing compound biosynthetic process GO:0034654 205 0.926
Human Mouse
regulation of gene expression GO:0010468 265 0.924
Mouse
organelle organization GO:0006996 227 0.921
Fly
chromatin modification GO:0016568 21 0.920
rna biosynthetic process GO:0032774 181 0.901
Mouse
negative regulation of cellular biosynthetic process GO:0031327 55 0.898
Mouse
regulation of rna biosynthetic process GO:2001141 213 0.890
Mouse
response to endogenous stimulus GO:0009719 83 0.889
cellular biosynthetic process GO:0044249 286 0.877
Human Mouse Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.863
Mouse
nitrogen compound metabolic process GO:0006807 319 0.861
Human Mouse Fly
negative regulation of cellular metabolic process GO:0031324 77 0.849
Mouse
positive regulation of gene expression GO:0010628 71 0.845
transcription from rna polymerase ii promoter GO:0006366 80 0.834
Mouse
sensory organ development GO:0007423 393 0.834
response to inorganic substance GO:0010035 38 0.833
chromatin organization GO:0006325 22 0.809
transcription dna templated GO:0006351 181 0.796
Mouse
dna catabolic process GO:0006308 1 0.789
Human
gene expression GO:0010467 252 0.768
Mouse
immune system process GO:0002376 241 0.763
Fly
regulation of transcription dna templated GO:0006355 213 0.748
Mouse
dna metabolic process GO:0006259 27 0.734
Human Mouse Fly
negative regulation of biosynthetic process GO:0009890 55 0.718
Mouse
negative regulation of transcription dna templated GO:0045892 45 0.700
Mouse
eye development GO:0001654 277 0.695
negative regulation of cellular process GO:0048523 283 0.687
Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.684
Human Mouse
larval development GO:0002164 2 0.674
cellular localization GO:0051641 97 0.666
gland development GO:0048732 143 0.664
heterocycle metabolic process GO:0046483 290 0.644
Human Mouse Fly
regulation of primary metabolic process GO:0080090 311 0.638
Human Mouse
cellular macromolecule biosynthetic process GO:0034645 224 0.629
Human Mouse Fly
small molecule metabolic process GO:0044281 77 0.601
positive regulation of macromolecule metabolic process GO:0010604 93 0.599
Human
cell cycle GO:0007049 93 0.598
Fly
dna methylation on cytosine GO:0032776 3 0.591
response to estrogen GO:0043627 27 0.585
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.579
Mouse
response to organic cyclic compound GO:0014070 51 0.548
response to drug GO:0042493 3 0.535
cell morphogenesis involved in differentiation GO:0000904 195 0.533
negative regulation of nucleic acid templated transcription GO:1903507 45 0.518
Mouse
response to metal ion GO:0010038 34 0.515
single organism metabolic process GO:0044710 217 0.509
Human Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.503
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.495
Mouse
positive regulation of metabolic process GO:0009893 108 0.468
Human
immune system development GO:0002520 191 0.461
response to organic substance GO:0010033 153 0.459
double strand break repair GO:0006302 3 0.457
positive regulation of cellular protein metabolic process GO:0032270 22 0.448
deoxyribonucleotide biosynthetic process GO:0009263 1 0.443
retina development in camera type eye GO:0060041 146 0.434
meiosis i GO:0007127 1 0.420
camera type eye morphogenesis GO:0048593 108 0.417
regulation of macromolecule metabolic process GO:0060255 317 0.411
Human Mouse
nucleic acid templated transcription GO:0097659 181 0.411
Mouse
regulation of rna metabolic process GO:0051252 224 0.409
Mouse
response to lipid GO:0033993 60 0.401
organonitrogen compound metabolic process GO:1901564 74 0.394
mitotic dna damage checkpoint GO:0044773 4 0.390
reciprocal dna recombination GO:0035825 1 0.390
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.375
Mouse
carboxylic acid metabolic process GO:0019752 22 0.374
cell cycle process GO:0022402 53 0.371
Fly
death GO:0016265 121 0.369
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.358
Human
cellular response to organic substance GO:0071310 105 0.349
negative regulation of cell death GO:0060548 60 0.345
aging GO:0007568 2 0.345
regulation of cellular component organization GO:0051128 86 0.343
catabolic process GO:0009056 32 0.343
Human
cellular protein metabolic process GO:0044267 129 0.340
sensory organ morphogenesis GO:0090596 200 0.330
cellular response to oxygen containing compound GO:1901701 20 0.327
negative regulation of biological process GO:0048519 304 0.324
Mouse
response to chemical GO:0042221 320 0.321
cellular macromolecule catabolic process GO:0044265 12 0.317
Human
cellular amine metabolic process GO:0044106 2 0.311
response to stress GO:0006950 263 0.310
Human Mouse
apoptotic process GO:0006915 116 0.309
mitotic dna integrity checkpoint GO:0044774 4 0.297
regulation of biosynthetic process GO:0009889 250 0.295
Mouse
response to amino acid GO:0043200 2 0.294
negative regulation of signaling GO:0023057 96 0.293
cell death GO:0008219 121 0.290
response to steroid hormone GO:0048545 35 0.280
aromatic compound biosynthetic process GO:0019438 217 0.276
Human Mouse
camera type eye development GO:0043010 222 0.272
negative regulation of protein metabolic process GO:0051248 16 0.270
nucleocytoplasmic transport GO:0006913 4 0.270
negative regulation of metabolic process GO:0009892 86 0.269
Mouse
chromosome organization involved in meiosis GO:0070192 1 0.266
response to oxygen containing compound GO:1901700 55 0.265
positive regulation of chromatin modification GO:1903310 1 0.262
rna metabolic process GO:0016070 219 0.260
Mouse
regulation of protein transport GO:0051223 3 0.253
positive regulation of nucleic acid templated transcription GO:1903508 57 0.252
negative regulation of response to stimulus GO:0048585 104 0.252
positive regulation of cellular process GO:0048522 201 0.248
Human
establishment of localization in cell GO:0051649 77 0.247
hemopoiesis GO:0030097 183 0.244
negative regulation of rna metabolic process GO:0051253 48 0.241
Mouse
sister chromatid cohesion GO:0007062 2 0.241
intracellular signal transduction GO:0035556 85 0.238
response to biotic stimulus GO:0009607 97 0.238
multicellular organismal homeostasis GO:0048871 29 0.238
mitotic cell cycle checkpoint GO:0007093 5 0.235
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.235
Mouse
negative regulation of cell communication GO:0010648 96 0.222
jak stat cascade GO:0007259 5 0.222
cellular component biogenesis GO:0044085 178 0.221
single organism organelle organization GO:1902589 199 0.217
Fly
regulation of apoptotic process GO:0042981 98 0.214
programmed cell death GO:0012501 119 0.214
astrocyte differentiation GO:0048708 1 0.211
blood circulation GO:0008015 87 0.205
response to hormone GO:0009725 48 0.203
lipoprotein catabolic process GO:0042159 1 0.200
macromolecule catabolic process GO:0009057 15 0.195
Human
retina morphogenesis in camera type eye GO:0060042 79 0.192
organic substance catabolic process GO:1901575 28 0.192
Human
cellular response to chemical stimulus GO:0070887 157 0.191
mitotic cell cycle GO:0000278 64 0.190
Fly
anatomical structure homeostasis GO:0060249 36 0.190
positive regulation of biosynthetic process GO:0009891 68 0.188
purine containing compound metabolic process GO:0072521 29 0.185
regulation of biological quality GO:0065008 263 0.185
regulation of cell proliferation GO:0042127 37 0.184
homeostatic process GO:0042592 142 0.178
positive regulation of biological process GO:0048518 253 0.177
Human
regulation of cell cycle GO:0051726 52 0.173
cell surface receptor signaling pathway GO:0007166 325 0.171
response to acid chemical GO:0001101 17 0.167
cellular amino acid metabolic process GO:0006520 7 0.166
positive regulation of histone modification GO:0031058 1 0.161
negative regulation of signal transduction GO:0009968 94 0.160
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.159
Mouse
negative regulation of rna biosynthetic process GO:1902679 45 0.158
Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.154
Human Mouse
negative regulation of macromolecule metabolic process GO:0010605 76 0.153
Mouse
cellular response to endogenous stimulus GO:0071495 68 0.150
recombinational repair GO:0000725 1 0.150
eye morphogenesis GO:0048592 144 0.150
thymus development GO:0048538 10 0.147
cellular nitrogen compound catabolic process GO:0044270 15 0.147
Human
response to cadmium ion GO:0046686 14 0.147
single organism localization GO:1902578 225 0.147
protein localization GO:0008104 40 0.144
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.142
single organism transport GO:0044765 206 0.140
regulation of cell death GO:0010941 103 0.137
regulation of protein metabolic process GO:0051246 56 0.136
positive regulation of nuclease activity GO:0032075 1 0.132
Human
tissue homeostasis GO:0001894 25 0.131
neuron projection morphogenesis GO:0048812 161 0.131
regulation of macromolecule biosynthetic process GO:0010556 225 0.124
Mouse
negative regulation of apoptotic process GO:0043066 55 0.119
rna localization GO:0006403 4 0.118
regulation of mitotic cell cycle GO:0007346 25 0.118
heart contraction GO:0060047 71 0.115
retina layer formation GO:0010842 24 0.115
synapsis GO:0007129 1 0.114
regulation of localization GO:0032879 104 0.114
regulation of establishment of protein localization GO:0070201 4 0.112
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.112
developmental process involved in reproduction GO:0003006 27 0.110
neuroblast proliferation GO:0007405 2 0.110
single organism biosynthetic process GO:0044711 71 0.109
Human
embryonic digestive tract development GO:0048566 4 0.108
covalent chromatin modification GO:0016569 20 0.108
meiotic nuclear division GO:0007126 4 0.107
positive regulation of rna biosynthetic process GO:1902680 57 0.107
regulation of cellular amine metabolic process GO:0033238 0 0.106
positive regulation of cytoskeleton organization GO:0051495 3 0.105
negative regulation of gene expression GO:0010629 65 0.104
Mouse
dna biosynthetic process GO:0071897 3 0.104
Human
response to nitrogen compound GO:1901698 19 0.103
carbohydrate derivative metabolic process GO:1901135 61 0.103
cellular response to biotic stimulus GO:0071216 3 0.103
amine metabolic process GO:0009308 2 0.101
oxoacid metabolic process GO:0043436 31 0.100
negative regulation of programmed cell death GO:0043069 58 0.100
regulation of nuclease activity GO:0032069 1 0.099
Human
positive regulation of transport GO:0051050 2 0.099
response to decreased oxygen levels GO:0036293 25 0.099
cellular component disassembly GO:0022411 1 0.098
growth GO:0040007 174 0.098
regulation of histone h3 k9 methylation GO:0051570 2 0.098
cellular response to lipid GO:0071396 39 0.096
negative regulation of endothelial cell migration GO:0010596 1 0.091
regulation of cellular protein metabolic process GO:0032268 52 0.091
spindle assembly GO:0051225 2 0.091
regulation of dna replication GO:0006275 3 0.089
regulation of gene expression epigenetic GO:0040029 11 0.089
regulation of cellular biosynthetic process GO:0031326 245 0.089
Mouse
positive regulation of neural precursor cell proliferation GO:2000179 1 0.089
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.089
guanosine containing compound metabolic process GO:1901068 4 0.088
axonogenesis GO:0007409 152 0.088
cellular ketone metabolic process GO:0042180 11 0.086
response to temperature stimulus GO:0009266 15 0.085
aromatic compound catabolic process GO:0019439 15 0.085
Human
negative regulation of chromosome organization GO:2001251 1 0.085
phosphorus metabolic process GO:0006793 109 0.083
cell cycle checkpoint GO:0000075 7 0.083
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.082
meiotic cell cycle process GO:1903046 3 0.080
cellular macromolecular complex assembly GO:0034622 24 0.080
mitotic cell cycle process GO:1903047 48 0.080
Fly
cell morphogenesis GO:0000902 289 0.079
hepaticobiliary system development GO:0061008 98 0.079
tube morphogenesis GO:0035239 349 0.079
dicarboxylic acid metabolic process GO:0043648 1 0.077
cell division GO:0051301 20 0.077
positive regulation of cellular biosynthetic process GO:0031328 68 0.076
double strand break repair via homologous recombination GO:0000724 1 0.076
nuclear transport GO:0051169 4 0.074
cellular component assembly GO:0022607 170 0.073
positive regulation of protein complex assembly GO:0031334 2 0.072
macromolecule modification GO:0043412 111 0.071
regulation of cell differentiation GO:0045595 142 0.071
regulation of response to stimulus GO:0048583 269 0.069
mitotic sister chromatid cohesion GO:0007064 2 0.068
retina homeostasis GO:0001895 12 0.067
regulation of metabolic process GO:0019222 359 0.067
Human Mouse
cell projection morphogenesis GO:0048858 244 0.065
cellular response to hormone stimulus GO:0032870 39 0.064
cell proliferation GO:0008283 80 0.064
regulation of signal transduction GO:0009966 225 0.062
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.062
Mouse
regulation of programmed cell death GO:0043067 101 0.061
regulation of multicellular organismal process GO:0051239 277 0.060
response to external biotic stimulus GO:0043207 97 0.059
response to abiotic stimulus GO:0009628 122 0.058
regulation of developmental process GO:0050793 247 0.057
photoreceptor cell differentiation GO:0046530 55 0.057
establishment of localization GO:0051234 244 0.056
positive regulation of oligodendrocyte differentiation GO:0048714 1 0.056
regulation of cellular ketone metabolic process GO:0010565 7 0.056
regulation of cellular amino acid metabolic process GO:0006521 0 0.056
signal transduction GO:0007165 455 0.055
male gamete generation GO:0048232 7 0.055
cellular response to external stimulus GO:0071496 2 0.054
histone modification GO:0016570 20 0.054
heart process GO:0003015 71 0.054
homeostasis of number of cells GO:0048872 62 0.052
cellular macromolecule localization GO:0070727 21 0.052
positive regulation of rna metabolic process GO:0051254 59 0.052
cellular component morphogenesis GO:0032989 336 0.051
mitotic nuclear division GO:0007067 18 0.051
response to alcohol GO:0097305 14 0.049
erythrocyte differentiation GO:0030218 54 0.048
macromolecular complex subunit organization GO:0043933 74 0.048
Fly
neuroblast fate commitment GO:0014017 1 0.048
phosphate containing compound metabolic process GO:0006796 108 0.047
energy reserve metabolic process GO:0006112 2 0.047
heterocycle catabolic process GO:0046700 15 0.046
Human
cellular response to dna damage stimulus GO:0006974 24 0.046
Human Mouse
positive regulation of cell cycle GO:0045787 3 0.046
positive regulation of molecular function GO:0044093 33 0.046
Human
response to ketone GO:1901654 1 0.045
transport GO:0006810 220 0.045
embryonic organ morphogenesis GO:0048562 274 0.045
embryonic digestive tract morphogenesis GO:0048557 3 0.044
organic acid metabolic process GO:0006082 31 0.044
neuron projection development GO:0031175 180 0.044
guanosine containing compound catabolic process GO:1901069 2 0.042
dna repair GO:0006281 6 0.042
Human Mouse
response to external stimulus GO:0009605 264 0.042
negative regulation of developmental process GO:0051093 65 0.041
organic substance transport GO:0071702 58 0.040
regulation of cell communication GO:0010646 232 0.039
ribonucleotide metabolic process GO:0009259 27 0.038
embryo development ending in birth or egg hatching GO:0009792 271 0.038
regulation of chromatin organization GO:1902275 5 0.037
organ regeneration GO:0031100 1 0.037
protein metabolic process GO:0019538 183 0.037
regulation of dna catabolic process GO:1903624 1 0.036
Human
i kappab kinase nf kappab signaling GO:0007249 4 0.036
negative regulation of gene silencing GO:0060969 1 0.036
cellular response to organic cyclic compound GO:0071407 38 0.035
cellular response to stress GO:0033554 62 0.035
Human Mouse
positive regulation of chromosome organization GO:2001252 1 0.035
nucleotide metabolic process GO:0009117 28 0.035
cell part morphogenesis GO:0032990 246 0.035
embryonic organ development GO:0048568 381 0.035
pyrimidine containing compound biosynthetic process GO:0072528 2 0.034
response to organonitrogen compound GO:0010243 12 0.034
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 10 0.034
negative regulation of mitotic cell cycle phase transition GO:1901991 5 0.034
negative regulation of cellular protein metabolic process GO:0032269 16 0.034
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.033
positive regulation of protein metabolic process GO:0051247 23 0.033
rna transport GO:0050658 2 0.032
double strand break repair via nonhomologous end joining GO:0006303 1 0.032
reciprocal meiotic recombination GO:0007131 1 0.032
digestive tract development GO:0048565 265 0.031
intra s dna damage checkpoint GO:0031573 1 0.031
positive regulation of cellular component organization GO:0051130 13 0.031
regulation of protein catabolic process GO:0042176 1 0.030
spermatid development GO:0007286 2 0.030
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.030
regulation of binding GO:0051098 3 0.030
protein localization to nucleus GO:0034504 3 0.029
single organism catabolic process GO:0044712 13 0.029
negative regulation of protein phosphorylation GO:0001933 4 0.029
camera type eye photoreceptor cell differentiation GO:0060219 19 0.028
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.028
Mouse
regulation of dna metabolic process GO:0051052 11 0.028
Human
regulation of hydrolase activity GO:0051336 28 0.028
Human
positive regulation of cellular component biogenesis GO:0044089 3 0.028
maintenance of dna repeat elements GO:0043570 2 0.028
vesicle mediated transport GO:0016192 22 0.027
regulation of multicellular organismal development GO:2000026 223 0.027
protein import GO:0017038 3 0.026
regulation of neuron apoptotic process GO:0043523 17 0.026
exocrine pancreas development GO:0031017 28 0.026
cellular response to molecule of bacterial origin GO:0071219 3 0.026
positive regulation of cellular amine metabolic process GO:0033240 0 0.026
positive regulation of gliogenesis GO:0014015 2 0.026
epithelial cell differentiation GO:0030855 116 0.026
Human
regulation of cell cycle phase transition GO:1901987 8 0.026
single organism cellular localization GO:1902580 46 0.025
dendrite development GO:0016358 9 0.025
regulation of epithelial cell proliferation GO:0050678 3 0.025
female gamete generation GO:0007292 14 0.025
organic cyclic compound catabolic process GO:1901361 15 0.025
Human
negative regulation of cell cycle process GO:0010948 9 0.024
stem cell proliferation GO:0072089 4 0.024
cellular catabolic process GO:0044248 27 0.024
Human
positive regulation of cytokine production GO:0001819 2 0.024
negative regulation of histone modification GO:0031057 1 0.024
circulatory system process GO:0003013 87 0.024
dna recombination GO:0006310 5 0.024
positive regulation of cell death GO:0010942 29 0.024
liver development GO:0001889 96 0.024
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.024
regulation of transport GO:0051049 45 0.024
positive regulation of hydrolase activity GO:0051345 13 0.023
Human
response to hypoxia GO:0001666 25 0.023
positive regulation of catalytic activity GO:0043085 25 0.023
Human
positive regulation of catabolic process GO:0009896 4 0.023
Human
negative regulation of cellular component organization GO:0051129 16 0.023
response to glucocorticoid GO:0051384 1 0.023
negative regulation of intracellular signal transduction GO:1902532 22 0.023
cellular response to reactive oxygen species GO:0034614 2 0.023
cellular component maintenance GO:0043954 3 0.022
positive regulation of phosphate metabolic process GO:0045937 21 0.022
germ cell development GO:0007281 22 0.020
central nervous system morphogenesis GO:0021551 12 0.020
digestive system development GO:0055123 289 0.020
multi organism reproductive process GO:0044703 36 0.020
nucleoside phosphate metabolic process GO:0006753 28 0.020
cell death in response to oxidative stress GO:0036473 2 0.020
regulation of cytoplasmic transport GO:1903649 4 0.020
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.020
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.020
methylation GO:0032259 22 0.020
protein destabilization GO:0031648 1 0.020
regulation of catalytic activity GO:0050790 55 0.020
Human
regulation of protein complex assembly GO:0043254 3 0.020
inner ear receptor cell fate commitment GO:0060120 4 0.020
negative regulation of catabolic process GO:0009895 3 0.019
regulation of protein localization to nucleus GO:1900180 2 0.019
positive regulation of transcription dna templated GO:0045893 57 0.019
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.019
nucleic acid transport GO:0050657 2 0.019
generation of neurons GO:0048699 385 0.019
positive regulation of glial cell differentiation GO:0045687 1 0.019
extracellular fibril organization GO:0043206 1 0.019
cellular response to organonitrogen compound GO:0071417 5 0.018
modification dependent protein catabolic process GO:0019941 3 0.018
protein acetylation GO:0006473 2 0.018
macromolecular complex assembly GO:0065003 35 0.018
regulation of intracellular protein transport GO:0033157 3 0.018
histone h3 k4 methylation GO:0051568 2 0.017
alpha amino acid metabolic process GO:1901605 3 0.017
myeloid cell homeostasis GO:0002262 56 0.017
neural retina development GO:0003407 49 0.017
multicellular organism growth GO:0035264 4 0.017
response to heat GO:0009408 6 0.017
muscle organ development GO:0007517 101 0.017
positive regulation of cellular component movement GO:0051272 11 0.017
cellular protein modification process GO:0006464 100 0.017
positive regulation of cell communication GO:0010647 56 0.017
b cell differentiation GO:0030183 1 0.016
zymogen activation GO:0031638 3 0.016
determination of heart left right asymmetry GO:0061371 117 0.016
spermatid differentiation GO:0048515 2 0.016
telomere organization GO:0032200 1 0.016
regulation of proteolysis GO:0030162 24 0.016
cellular response to light stimulus GO:0071482 4 0.016
regulation of phosphate metabolic process GO:0019220 43 0.016
response to estradiol GO:0032355 6 0.016
central nervous system development GO:0007417 387 0.016
intrinsic apoptotic signaling pathway GO:0097193 20 0.015
lipid homeostasis GO:0055088 3 0.015
cell migration GO:0016477 237 0.015
protein acylation GO:0043543 3 0.015
negative regulation of cellular catabolic process GO:0031330 3 0.015
bone remodeling GO:0046849 2 0.015
response to antibiotic GO:0046677 1 0.015
response to xenobiotic stimulus GO:0009410 45 0.015
erythrocyte homeostasis GO:0034101 55 0.015
tissue remodeling GO:0048771 4 0.015
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.015
b cell activation GO:0042113 2 0.015
protein heterooligomerization GO:0051291 1 0.015
regulation of heart growth GO:0060420 2 0.015
organelle fission GO:0048285 23 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
taste bud morphogenesis GO:0061194 3 0.015
gliogenesis GO:0042063 45 0.014
apoptotic signaling pathway GO:0097190 23 0.014
dendrite morphogenesis GO:0048813 5 0.014
microtubule polymerization GO:0046785 2 0.014
neuron apoptotic process GO:0051402 20 0.014
peripheral nervous system neuron development GO:0048935 22 0.014
microtubule cytoskeleton organization GO:0000226 33 0.014
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
regulation of mitosis GO:0007088 9 0.014
regulation of intracellular signal transduction GO:1902531 57 0.014
specification of symmetry GO:0009799 204 0.014
generation of precursor metabolites and energy GO:0006091 5 0.013
regulation of cell activation GO:0050865 1 0.013
response to lipopolysaccharide GO:0032496 13 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.013
epithelial tube morphogenesis GO:0060562 148 0.013
regulation of molecular function GO:0065009 70 0.013
Human
dna templated transcription elongation GO:0006354 3 0.013
regulation of cellular response to oxidative stress GO:1900407 2 0.013
negative regulation of chromatin modification GO:1903309 1 0.013
regulation of bone remodeling GO:0046850 2 0.013
cellular protein catabolic process GO:0044257 4 0.013
positive regulation of signal transduction GO:0009967 56 0.013
regulation of mrna processing GO:0050684 3 0.013
proteasomal protein catabolic process GO:0010498 2 0.012
axon development GO:0061564 166 0.012
nucleic acid phosphodiester bond hydrolysis GO:0090305 6 0.012
Human
regulation of growth GO:0040008 42 0.012
centrosome cycle GO:0007098 1 0.012
regulation of dna damage response signal transduction by p53 class mediator GO:0043516 4 0.012
regulation of protein phosphorylation GO:0001932 18 0.012
proteolysis GO:0006508 38 0.012
head development GO:0060322 303 0.012
single organism intracellular transport GO:1902582 25 0.012
regulation of catabolic process GO:0009894 12 0.012
Human
fibril organization GO:0097435 1 0.012
protein complex assembly GO:0006461 30 0.012
pancreas development GO:0031016 84 0.012
regulation of cgmp biosynthetic process GO:0030826 6 0.012
phosphorylation GO:0016310 69 0.011
eye photoreceptor cell differentiation GO:0001754 45 0.011
regulation of signaling GO:0023051 235 0.011
negative regulation of dna metabolic process GO:0051053 4 0.011
cell aging GO:0007569 2 0.011
ribose phosphate metabolic process GO:0019693 27 0.011
positive regulation of endopeptidase activity GO:0010950 10 0.011
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.011
female gonad development GO:0008585 4 0.011
positive regulation of striated muscle cell differentiation GO:0051155 1 0.011
regulation of phosphorus metabolic process GO:0051174 43 0.011
regulation of tissue remodeling GO:0034103 2 0.011
regulation of multicellular organism growth GO:0040014 4 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011

pcna disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
large intestine cancer DOID:5672 0 0.090
gastrointestinal system cancer DOID:3119 0 0.090
intestinal cancer DOID:10155 0 0.090
cancer DOID:162 0 0.090
disease of cellular proliferation DOID:14566 0 0.090
organ system cancer DOID:0050686 0 0.090
colorectal cancer DOID:9256 0 0.080
colon cancer DOID:219 0 0.073
disease of anatomical entity DOID:7 0 0.045
disease of mental health DOID:150 0 0.044
developmental disorder of mental health DOID:0060037 0 0.044
benign neoplasm DOID:0060072 0 0.021
disease of metabolism DOID:0014667 0 0.017
cell type benign neoplasm DOID:0060084 0 0.015