Danio rerio

0 known processes

pcsk1

proprotein convertase subtilisin/kexin type 1

pcsk1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
peptide metabolic process GO:0006518 1 0.664
Mouse
anterior lateral line system development GO:0048898 9 0.605
Zebrafish
neuromast development GO:0048884 46 0.540
Zebrafish
embryonic viscerocranium morphogenesis GO:0048703 52 0.490
Zebrafish
cellular amide metabolic process GO:0043603 4 0.446
Mouse
mechanosensory lateral line system development GO:0048881 49 0.437
Zebrafish
fin development GO:0033333 77 0.420
Zebrafish
embryonic skeletal system morphogenesis GO:0048704 93 0.374
Zebrafish
aging GO:0007568 2 0.361
cartilage morphogenesis GO:0060536 13 0.353
Zebrafish
embryonic skeletal system development GO:0048706 97 0.340
Zebrafish
hatching GO:0035188 4 0.324
lateral line system development GO:0048925 76 0.310
Zebrafish
anterior lateral line development GO:0048899 5 0.287
Zebrafish
sensory organ development GO:0007423 393 0.285
Zebrafish
regulation of biological quality GO:0065008 263 0.262
Mouse
organism emergence from protective structure GO:0071684 4 0.243
negative regulation of reproductive process GO:2000242 3 0.242
negative regulation of biological process GO:0048519 304 0.239
appendage development GO:0048736 80 0.226
Zebrafish
negative regulation of response to stimulus GO:0048585 104 0.221
cellular macromolecule metabolic process GO:0044260 391 0.219
lateral line development GO:0048882 66 0.213
Zebrafish
embryonic organ development GO:0048568 381 0.207
Zebrafish
gene expression GO:0010467 252 0.198
Mouse
connective tissue development GO:0061448 99 0.193
Zebrafish
locomotion GO:0040011 313 0.180
hormone metabolic process GO:0042445 19 0.174
Mouse
appendage morphogenesis GO:0035107 56 0.166
Zebrafish
regulation of gene expression GO:0010468 265 0.162
carbohydrate homeostasis GO:0033500 1 0.162
larval behavior GO:0030537 5 0.160
larval locomotory behavior GO:0008345 5 0.158
regulation of reproductive process GO:2000241 4 0.158
central nervous system development GO:0007417 387 0.156
sensory system development GO:0048880 76 0.149
Zebrafish
regulation of multicellular organismal process GO:0051239 277 0.149
negative regulation of multicellular organismal process GO:0051241 69 0.149
glucose import GO:0046323 2 0.148
response to external stimulus GO:0009605 264 0.146
cellular nitrogen compound metabolic process GO:0034641 290 0.137
Mouse
innate immune response GO:0045087 13 0.134
protein metabolic process GO:0019538 183 0.133
Mouse
regulation of response to stimulus GO:0048583 269 0.124
protein processing GO:0016485 12 0.123
Mouse
embryonic organ morphogenesis GO:0048562 274 0.117
Zebrafish
synaptic target recognition GO:0008039 1 0.112
embryo development ending in birth or egg hatching GO:0009792 271 0.108
Zebrafish
organic substance biosynthetic process GO:1901576 289 0.106
Mouse
cellular biosynthetic process GO:0044249 286 0.099
Mouse
protein maturation GO:0051604 12 0.092
Mouse
response to oxidative stress GO:0006979 11 0.092
inner ear development GO:0048839 126 0.090
epithelial cell development GO:0002064 42 0.089
regulation of cytokine production GO:0001817 3 0.087
homeostatic process GO:0042592 142 0.086
maintenance of location GO:0051235 4 0.084
multi organism process GO:0051704 134 0.082
response to monosaccharide GO:0034284 3 0.082
nucleobase containing compound metabolic process GO:0006139 274 0.081
nucleic acid metabolic process GO:0090304 244 0.077
chemical homeostasis GO:0048878 49 0.077
signal transduction GO:0007165 455 0.076
response to chemical GO:0042221 320 0.073
negative regulation of cellular process GO:0048523 283 0.071
response to stress GO:0006950 263 0.071
rna metabolic process GO:0016070 219 0.070
cell surface receptor signaling pathway GO:0007166 325 0.070
nuclear transport GO:0051169 4 0.069
establishment of localization GO:0051234 244 0.066
epithelial cell differentiation GO:0030855 116 0.066
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.066
transport GO:0006810 220 0.065
organic anion transport GO:0015711 15 0.063
positive regulation of transport GO:0051050 2 0.061
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.061
fin morphogenesis GO:0033334 53 0.059
Zebrafish
ear development GO:0043583 127 0.059
multi organism cellular process GO:0044764 2 0.059
nitrogen compound metabolic process GO:0006807 319 0.058
Mouse
response to topologically incorrect protein GO:0035966 2 0.058
cartilage development GO:0051216 96 0.057
Zebrafish
dicarboxylic acid transport GO:0006835 1 0.057
positive regulation of neuron death GO:1901216 1 0.056
regulation of muscle contraction GO:0006937 3 0.055
larval development GO:0002164 2 0.055
regulation of cellular biosynthetic process GO:0031326 245 0.055
cellular component assembly GO:0022607 170 0.055
chordate embryonic development GO:0043009 271 0.054
Zebrafish
response to biotic stimulus GO:0009607 97 0.054
regulation of multicellular organism growth GO:0040014 4 0.052
regulation of rna metabolic process GO:0051252 224 0.051
negative regulation of behavior GO:0048521 6 0.050
regulation of hormone levels GO:0010817 21 0.050
Mouse
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.049
negative regulation of defense response GO:0031348 2 0.048
nucleic acid templated transcription GO:0097659 181 0.048
negative regulation of gene expression GO:0010629 65 0.048
regulation of hormone secretion GO:0046883 2 0.047
single organism transport GO:0044765 206 0.047
regulation of cytoplasmic transport GO:1903649 4 0.047
negative regulation of nucleic acid templated transcription GO:1903507 45 0.046
generation of neurons GO:0048699 385 0.046
determination of bilateral symmetry GO:0009855 204 0.046
hormone transport GO:0009914 2 0.045
rna biosynthetic process GO:0032774 181 0.044
hormone mediated signaling pathway GO:0009755 9 0.044
multicellular organism growth GO:0035264 4 0.044
sodium ion transmembrane transport GO:0035725 21 0.043
regulation of metabolic process GO:0019222 359 0.043
brain development GO:0007420 293 0.042
phagocytosis engulfment GO:0006911 1 0.042
cellular lipid catabolic process GO:0044242 3 0.040
immunoglobulin mediated immune response GO:0016064 3 0.040
regulation of rna biosynthetic process GO:2001141 213 0.040
heart development GO:0007507 313 0.039
response to drug GO:0042493 3 0.039
heart contraction GO:0060047 71 0.039
response to external biotic stimulus GO:0043207 97 0.039
response to hexose GO:0009746 3 0.039
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.039
regulation of nucleocytoplasmic transport GO:0046822 2 0.039
cellular nitrogen compound biosynthetic process GO:0044271 218 0.038
Mouse
liver development GO:0001889 96 0.038
catabolic process GO:0009056 32 0.037
response to endogenous stimulus GO:0009719 83 0.037
cellular response to organic substance GO:0071310 105 0.037
lipid storage GO:0019915 1 0.037
regulation of cell cycle GO:0051726 52 0.037
transcription from rna polymerase ii promoter GO:0006366 80 0.036
hormone secretion GO:0046879 2 0.036
regulation of locomotion GO:0040012 55 0.035
regulation of establishment of protein localization GO:0070201 4 0.035
very long chain fatty acid biosynthetic process GO:0042761 4 0.034
phagocytosis GO:0006909 3 0.034
i kappab kinase nf kappab signaling GO:0007249 4 0.034
neuron differentiation GO:0030182 353 0.033
nik nf kappab signaling GO:0038061 1 0.033
neuron development GO:0048666 262 0.033
meiotic cell cycle process GO:1903046 3 0.033
negative regulation of peptidase activity GO:0010466 10 0.033
regulation of behavior GO:0050795 24 0.032
cellular response to unfolded protein GO:0034620 2 0.032
urogenital system development GO:0001655 97 0.032
proteolysis GO:0006508 38 0.032
Mouse
immune system process GO:0002376 241 0.032
peptide transport GO:0015833 1 0.032
defense response GO:0006952 47 0.032
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.032
cellular macromolecule biosynthetic process GO:0034645 224 0.032
regulation of cell communication GO:0010646 232 0.032
negative regulation of cell communication GO:0010648 96 0.032
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.031
regulation of peptidase activity GO:0052547 23 0.031
cell proliferation GO:0008283 80 0.031
behavior GO:0007610 74 0.031
multi organism reproductive process GO:0044703 36 0.030
negative regulation of cytokine production GO:0001818 1 0.030
adult behavior GO:0030534 2 0.030
cation transmembrane transport GO:0098655 65 0.030
positive regulation of cytokine production GO:0001819 2 0.030
programmed cell death GO:0012501 119 0.030
negative regulation of metabolic process GO:0009892 86 0.030
cell part morphogenesis GO:0032990 246 0.030
complement activation GO:0006956 3 0.029
regulation of transcription dna templated GO:0006355 213 0.029
carboxylic acid metabolic process GO:0019752 22 0.029
hepaticobiliary system development GO:0061008 98 0.029
positive regulation of biological process GO:0048518 253 0.029
regulation of signaling GO:0023051 235 0.029
biosynthetic process GO:0009058 294 0.029
Mouse
regulation of signal transduction GO:0009966 225 0.029
cellular component morphogenesis GO:0032989 336 0.029
cell cycle GO:0007049 93 0.029
regulation of nitrogen compound metabolic process GO:0051171 251 0.028
negative regulation of macromolecule metabolic process GO:0010605 76 0.028
cellular response to stress GO:0033554 62 0.028
response to alkaloid GO:0043279 2 0.028
zymogen activation GO:0031638 3 0.028
smooth muscle contraction GO:0006939 2 0.028
regulation of macromolecule biosynthetic process GO:0010556 225 0.028
positive regulation of rna biosynthetic process GO:1902680 57 0.028
stem cell proliferation GO:0072089 4 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.027
gastrulation GO:0007369 208 0.027
regulation of apoptotic process GO:0042981 98 0.027
cellular localization GO:0051641 97 0.027
positive regulation of translation GO:0045727 1 0.027
membrane lipid biosynthetic process GO:0046467 2 0.027
regulation of multicellular organismal development GO:2000026 223 0.026
meiotic nuclear division GO:0007126 4 0.026
cellular component movement GO:0006928 335 0.026
glucose homeostasis GO:0042593 1 0.026
heterocycle metabolic process GO:0046483 290 0.026
microtubule based movement GO:0007018 33 0.025
organic cyclic compound biosynthetic process GO:1901362 223 0.025
apoptotic process GO:0006915 116 0.025
system process GO:0003008 185 0.025
regulation of macromolecule metabolic process GO:0060255 317 0.025
positive regulation of cell cycle GO:0045787 3 0.024
regulation of protein catabolic process GO:0042176 1 0.024
response to carbohydrate GO:0009743 3 0.024
regulation of inflammatory response GO:0050727 2 0.024
female sex differentiation GO:0046660 4 0.024
regulation of synaptic plasticity GO:0048167 1 0.024
heterocycle biosynthetic process GO:0018130 215 0.024
death GO:0016265 121 0.024
fatty acid biosynthetic process GO:0006633 4 0.024
blood vessel development GO:0001568 246 0.023
humoral immune response mediated by circulating immunoglobulin GO:0002455 3 0.023
inflammatory response GO:0006954 8 0.023
cellular carbohydrate metabolic process GO:0044262 4 0.023
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.023
very long chain fatty acid metabolic process GO:0000038 4 0.023
localization of cell GO:0051674 244 0.023
striated muscle cell differentiation GO:0051146 129 0.023
response to other organism GO:0051707 97 0.023
meiotic chromosome segregation GO:0045132 3 0.022
regulation of protein transport GO:0051223 3 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.022
response to nitrogen compound GO:1901698 19 0.022
cellular response to extracellular stimulus GO:0031668 2 0.022
protein secretion GO:0009306 1 0.022
response to ketone GO:1901654 1 0.022
hematopoietic or lymphoid organ development GO:0048534 191 0.022
negative regulation of mapk cascade GO:0043409 4 0.022
cell killing GO:0001906 2 0.022
regulation of cellular metabolic process GO:0031323 320 0.022
regulation of sodium ion transport GO:0002028 2 0.022
reproduction GO:0000003 40 0.022
membrane invagination GO:0010324 1 0.022
regulation of membrane repolarization GO:0060306 1 0.022
regulation of cysteine type endopeptidase activity GO:2000116 21 0.022
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.021
cellular response to biotic stimulus GO:0071216 3 0.021
embryonic cranial skeleton morphogenesis GO:0048701 90 0.021
Zebrafish
hemopoiesis GO:0030097 183 0.021
regulation of nik nf kappab signaling GO:1901222 1 0.021
regulation of immune system process GO:0002682 34 0.021
negative regulation of translation GO:0017148 1 0.021
cellular response to chemical stimulus GO:0070887 157 0.021
interspecies interaction between organisms GO:0044419 4 0.021
specification of symmetry GO:0009799 204 0.021
er nucleus signaling pathway GO:0006984 2 0.021
response to wounding GO:0009611 116 0.020
cell death GO:0008219 121 0.020
regulation of primary metabolic process GO:0080090 311 0.020
cellular component biogenesis GO:0044085 178 0.020
monocarboxylic acid transport GO:0015718 5 0.020
regulation of synapse organization GO:0050807 3 0.020
transcription dna templated GO:0006351 181 0.020
organelle organization GO:0006996 227 0.020
energy reserve metabolic process GO:0006112 2 0.020
cellular protein catabolic process GO:0044257 4 0.020
cellular protein metabolic process GO:0044267 129 0.020
microtubule organizing center organization GO:0031023 1 0.020
sphingolipid biosynthetic process GO:0030148 2 0.020
plasminogen activation GO:0031639 3 0.020
nucleocytoplasmic transport GO:0006913 4 0.020
viral process GO:0016032 1 0.020
nuclear import GO:0051170 3 0.019
endoplasmic reticulum unfolded protein response GO:0030968 2 0.019
positive regulation of cell division GO:0051781 2 0.019
light adaption GO:0036367 1 0.019
positive regulation of cellular catabolic process GO:0031331 3 0.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.019
single organism localization GO:1902578 225 0.019
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.019
regulation of circadian rhythm GO:0042752 4 0.019
phosphate containing compound metabolic process GO:0006796 108 0.019
protein localization to nucleus GO:0034504 3 0.019
regulation of cellular response to oxidative stress GO:1900407 2 0.019
establishment of protein localization to organelle GO:0072594 4 0.019
regulation of response to stress GO:0080134 36 0.019
nucleobase containing compound biosynthetic process GO:0034654 205 0.019
gtp metabolic process GO:0046039 4 0.018
cellular response to topologically incorrect protein GO:0035967 2 0.018
neuromuscular process controlling balance GO:0050885 3 0.018
regulation of protein complex assembly GO:0043254 3 0.018
sexual reproduction GO:0019953 36 0.018
positive regulation of response to stimulus GO:0048584 80 0.018
lipid metabolic process GO:0006629 52 0.018
negative regulation of hydrolase activity GO:0051346 10 0.018
heart looping GO:0001947 94 0.017
regulation of translational initiation GO:0006446 1 0.017
cognition GO:0050890 1 0.017
regulation of cellular protein catabolic process GO:1903362 1 0.017
ion transmembrane transport GO:0034220 91 0.017
regulation of systemic arterial blood pressure GO:0003073 1 0.017
response to bacterium GO:0009617 58 0.017
organic substance catabolic process GO:1901575 28 0.017
cellular response to dsrna GO:0071359 1 0.017
response to glucose GO:0009749 3 0.017
negative regulation of signal transduction GO:0009968 94 0.017
immune response GO:0006955 28 0.017
single organism nuclear import GO:1902593 3 0.017
positive regulation of signal transduction GO:0009967 56 0.017
multicellular organismal response to stress GO:0033555 2 0.017
negative regulation of cellular catabolic process GO:0031330 3 0.017
regulation of stem cell proliferation GO:0072091 2 0.017
cellular aromatic compound metabolic process GO:0006725 295 0.017
response to nutrient GO:0007584 3 0.017
regulation of endopeptidase activity GO:0052548 23 0.017
dicarboxylic acid metabolic process GO:0043648 1 0.017
negative regulation of multi organism process GO:0043901 3 0.017
response to oxygen containing compound GO:1901700 55 0.017
regulation of defense response GO:0031347 14 0.016
cytokine mediated signaling pathway GO:0019221 7 0.016
macromolecule catabolic process GO:0009057 15 0.016
regulation of system process GO:0044057 40 0.016
protein complex localization GO:0031503 1 0.016
androgen metabolic process GO:0008209 2 0.016
protein targeting to nucleus GO:0044744 3 0.016
regulation of programmed cell death GO:0043067 101 0.016
single organism metabolic process GO:0044710 217 0.016
regulation of blood pressure GO:0008217 1 0.016
organic cyclic compound metabolic process GO:1901360 301 0.016
protein modification process GO:0036211 100 0.016
membrane fusion GO:0061025 2 0.016
positive regulation of catabolic process GO:0009896 4 0.016
cellular response to hormone stimulus GO:0032870 39 0.016
kidney development GO:0001822 92 0.016
cellular response to external stimulus GO:0071496 2 0.016
neuron recognition GO:0008038 18 0.016
regulation of protein targeting GO:1903533 2 0.016
negative regulation of secretion GO:0051048 2 0.016
positive regulation of cell communication GO:0010647 56 0.015
golgi vesicle transport GO:0048193 3 0.015
cell motility GO:0048870 244 0.015
meiosis i GO:0007127 1 0.015
protein import into nucleus GO:0006606 3 0.015
endocrine process GO:0050886 2 0.015
organic substance transport GO:0071702 58 0.015
macromolecule modification GO:0043412 111 0.015
b cell activation GO:0042113 2 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
cell migration GO:0016477 237 0.015
steroid hormone mediated signaling pathway GO:0043401 9 0.015
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.015
regulation of developmental process GO:0050793 247 0.015
response to unfolded protein GO:0006986 2 0.015
regeneration GO:0031099 91 0.015
response to virus GO:0009615 21 0.015
negative regulation of cell differentiation GO:0045596 46 0.014
determination of left right symmetry GO:0007368 179 0.014
positive regulation of cellular process GO:0048522 201 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
positive regulation of multicellular organismal process GO:0051240 52 0.014
tissue remodeling GO:0048771 4 0.014
cellular response to light stimulus GO:0071482 4 0.014
regulation of cell proliferation GO:0042127 37 0.014
regulation of biosynthetic process GO:0009889 250 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.014
regulation of neural precursor cell proliferation GO:2000177 3 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.014
regulation of cell death GO:0010941 103 0.014
regulation of blood vessel size GO:0050880 2 0.014
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.014
endothelial cell differentiation GO:0045446 20 0.014
myeloid cell differentiation GO:0030099 86 0.014
sensory perception of pain GO:0019233 1 0.014
glial cell migration GO:0008347 3 0.014
chloride transmembrane transport GO:1902476 4 0.014
b cell mediated immunity GO:0019724 3 0.014
regulation of protein localization to nucleus GO:1900180 2 0.014
long chain fatty acid metabolic process GO:0001676 1 0.014
axon development GO:0061564 166 0.014
granulocyte migration GO:0097530 11 0.014
epithelial tube morphogenesis GO:0060562 148 0.013
cellular protein modification process GO:0006464 100 0.013
regulation of nucleic acid templated transcription GO:1903506 213 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
cellular response to endogenous stimulus GO:0071495 68 0.013
pericardium morphogenesis GO:0003344 1 0.013
organonitrogen compound metabolic process GO:1901564 74 0.013
Mouse
lipid oxidation GO:0034440 1 0.013
cellular response to nutrient levels GO:0031669 2 0.013
protein import GO:0017038 3 0.013
response to hormone GO:0009725 48 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
leukocyte mediated cytotoxicity GO:0001909 1 0.013
negative regulation of rna metabolic process GO:0051253 48 0.013
fatty acid transport GO:0015908 1 0.013
complement activation classical pathway GO:0006958 3 0.013
neuron projection morphogenesis GO:0048812 161 0.013
cellular response to radiation GO:0071478 4 0.013
monocarboxylic acid catabolic process GO:0072329 3 0.013
anion transport GO:0006820 38 0.013
exocrine system development GO:0035272 28 0.013
regulation of localization GO:0032879 104 0.013
aromatic compound biosynthetic process GO:0019438 217 0.013
response to abiotic stimulus GO:0009628 122 0.013
positive regulation of epithelial cell proliferation GO:0050679 1 0.013
ion transport GO:0006811 114 0.012
negative regulation of epithelial cell proliferation GO:0050680 1 0.012
positive regulation of immune effector process GO:0002699 3 0.012
single organism organelle organization GO:1902589 199 0.012
cell projection organization GO:0030030 284 0.012
positive regulation of neural precursor cell proliferation GO:2000179 1 0.012
lateral inhibition GO:0046331 1 0.012
negative regulation of cellular biosynthetic process GO:0031327 55 0.012
negative regulation of protein phosphorylation GO:0001933 4 0.012
regulation of protein metabolic process GO:0051246 56 0.012
stem cell maintenance GO:0019827 4 0.012
eye development GO:0001654 277 0.012
cellular component assembly involved in morphogenesis GO:0010927 107 0.012
regulation of protein import into nucleus GO:0042306 2 0.012
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.012
organic acid transport GO:0015849 9 0.012
biological adhesion GO:0022610 40 0.012
regulation of mitotic cell cycle GO:0007346 25 0.012
centrosome organization GO:0051297 1 0.012
response to glucocorticoid GO:0051384 1 0.012
regulation of synapse assembly GO:0051963 3 0.012
response to organic substance GO:0010033 153 0.012
positive regulation of secretion GO:0051047 1 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
organelle fusion GO:0048284 3 0.012
regulation of intracellular signal transduction GO:1902531 57 0.012
positive regulation of cell killing GO:0031343 2 0.012
response to light stimulus GO:0009416 46 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
regulation of lymphocyte mediated immunity GO:0002706 1 0.011
muscle contraction GO:0006936 18 0.011
muscle system process GO:0003012 20 0.011
positive regulation of inflammatory response GO:0050729 1 0.011
cell death in response to oxidative stress GO:0036473 2 0.011
immune system development GO:0002520 191 0.011
dna catabolic process GO:0006308 1 0.011
protein catabolic process GO:0030163 7 0.011
cellular response to starvation GO:0009267 1 0.011
regulation of phosphorylation GO:0042325 26 0.011
natural killer cell mediated immunity GO:0002228 1 0.011
morphogenesis of an epithelium GO:0002009 333 0.011
macromolecule biosynthetic process GO:0009059 227 0.011
mrna cleavage involved in gene silencing by mirna GO:0035279 1 0.011
locomotory behavior GO:0007626 34 0.011
purine nucleoside monophosphate catabolic process GO:0009128 4 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.011
intracellular signal transduction GO:0035556 85 0.011
synaptic transmission cholinergic GO:0007271 4 0.011
long chain fatty acid biosynthetic process GO:0042759 1 0.011
glial cell proliferation GO:0014009 4 0.011
regulation of ph GO:0006885 3 0.011
defense response to other organism GO:0098542 33 0.011
cell cycle g2 m phase transition GO:0044839 4 0.011
cellular component disassembly GO:0022411 1 0.011
amide biosynthetic process GO:0043604 1 0.011
Mouse
response to organic cyclic compound GO:0014070 51 0.011
oxoacid metabolic process GO:0043436 31 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.011
negative regulation of transcription dna templated GO:0045892 45 0.011
epidermal cell differentiation GO:0009913 36 0.011
negative regulation of apoptotic process GO:0043066 55 0.011
regulation of embryonic development GO:0045995 47 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
response to radiation GO:0009314 51 0.011
regulation of ventricular cardiac muscle cell membrane repolarization GO:0060307 1 0.010
positive regulation of nucleotide catabolic process GO:0030813 1 0.010
head development GO:0060322 303 0.010
somatic muscle development GO:0007525 4 0.010
regulation of myotube differentiation GO:0010830 2 0.010
cellular amine metabolic process GO:0044106 2 0.010
regulation of glial cell proliferation GO:0060251 4 0.010
negative regulation of programmed cell death GO:0043069 58 0.010
embryonic skeletal joint development GO:0072498 3 0.010
fatty acid elongation GO:0030497 1 0.010
peptidyl serine modification GO:0018209 2 0.010
regulation of binding GO:0051098 3 0.010
canonical wnt signaling pathway GO:0060070 48 0.010
positive regulation of cellular metabolic process GO:0031325 94 0.010
response to uv GO:0009411 3 0.010
posttranscriptional gene silencing by rna GO:0035194 3 0.010
organonitrogen compound biosynthetic process GO:1901566 47 0.010
Mouse
positive regulation of cell adhesion GO:0045785 1 0.010
embryonic heart tube development GO:0035050 133 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.010
regulation of glucose import GO:0046324 1 0.010
negative regulation of cellular metabolic process GO:0031324 77 0.010
regulation of neuronal synaptic plasticity GO:0048168 1 0.010
regulation of tube size GO:0035150 2 0.010

pcsk1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
musculoskeletal system disease DOID:17 0 0.014
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014