Danio rerio

20 known processes

pcsk7

proprotein convertase subtilisin/kexin type 7

(Aliases: zgc:158336,wu:fj05c03)

pcsk7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
peptide metabolic process GO:0006518 1 0.548
anterior lateral line system development GO:0048898 9 0.463
cellular amide metabolic process GO:0043603 4 0.377
mechanosensory lateral line system development GO:0048881 49 0.365
neuromast development GO:0048884 46 0.338
lateral line system development GO:0048925 76 0.305
regulation of glucose import GO:0046324 1 0.304
appendage morphogenesis GO:0035107 56 0.303
cartilage morphogenesis GO:0060536 13 0.283
biosynthetic process GO:0009058 294 0.260
lateral line development GO:0048882 66 0.246
embryonic skeletal system development GO:0048706 97 0.245
embryonic skeletal system morphogenesis GO:0048704 93 0.227
regulation of rna metabolic process GO:0051252 224 0.225
appendage development GO:0048736 80 0.187
anterior lateral line development GO:0048899 5 0.179
hormone metabolic process GO:0042445 19 0.176
cellular nitrogen compound metabolic process GO:0034641 290 0.171
embryonic cranial skeleton morphogenesis GO:0048701 90 0.170
sensory organ development GO:0007423 393 0.158
organic substance biosynthetic process GO:1901576 289 0.150
protein processing GO:0016485 12 0.148
connective tissue development GO:0061448 99 0.126
positive regulation of glucose transport GO:0010828 1 0.126
chordate embryonic development GO:0043009 271 0.120
regulation of cellular biosynthetic process GO:0031326 245 0.118
multi organism cellular process GO:0044764 2 0.117
sensory system development GO:0048880 76 0.116
positive regulation of transport GO:0051050 2 0.115
lipid oxidation GO:0034440 1 0.115
hatching GO:0035188 4 0.113
positive regulation of stress activated mapk cascade GO:0032874 3 0.112
gene expression GO:0010467 252 0.109
cellular protein catabolic process GO:0044257 4 0.109
fin morphogenesis GO:0033334 53 0.104
regulation of fatty acid metabolic process GO:0019217 1 0.100
small molecule catabolic process GO:0044282 3 0.100
regulation of biological quality GO:0065008 263 0.099
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.097
nik nf kappab signaling GO:0038061 1 0.095
viral process GO:0016032 1 0.094
cartilage development GO:0051216 96 0.090
regulation of cellular metabolic process GO:0031323 320 0.090
regulation of protein localization to nucleus GO:1900180 2 0.087
aging GO:0007568 2 0.086
nucleic acid templated transcription GO:0097659 181 0.085
cellular lipid catabolic process GO:0044242 3 0.084
regulation of gene expression GO:0010468 265 0.084
regulation of glucose transport GO:0010827 1 0.083
innate immune response GO:0045087 13 0.081
i kappab kinase nf kappab signaling GO:0007249 4 0.081
regulation of proteolysis GO:0030162 24 0.080
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.077
regulation of intracellular protein transport GO:0033157 3 0.074
signal transduction GO:0007165 455 0.074
embryonic organ morphogenesis GO:0048562 274 0.074
nitrogen compound metabolic process GO:0006807 319 0.073
nucleobase containing compound metabolic process GO:0006139 274 0.071
nuclear transport GO:0051169 4 0.070
embryo development ending in birth or egg hatching GO:0009792 271 0.070
embryonic viscerocranium morphogenesis GO:0048703 52 0.069
negative regulation of catabolic process GO:0009895 3 0.068
synaptic target recognition GO:0008039 1 0.068
monocarboxylic acid catabolic process GO:0072329 3 0.067
embryonic organ development GO:0048568 381 0.066
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.066
organism emergence from protective structure GO:0071684 4 0.065
positive regulation of cytokine production GO:0001819 2 0.065
protein targeting to nucleus GO:0044744 3 0.065
protein metabolic process GO:0019538 183 0.065
urogenital system development GO:0001655 97 0.064
regulation of cytoplasmic transport GO:1903649 4 0.063
cellular biosynthetic process GO:0044249 286 0.062
fin development GO:0033333 77 0.061
glucose import GO:0046323 2 0.060
regulation of protein import into nucleus GO:0042306 2 0.059
cellular carbohydrate metabolic process GO:0044262 4 0.058
single organism localization GO:1902578 225 0.058
protein localization to nucleus GO:0034504 3 0.057
regulation of protein catabolic process GO:0042176 1 0.057
positive regulation of innate immune response GO:0045089 8 0.057
carboxylic acid catabolic process GO:0046395 3 0.057
carbohydrate homeostasis GO:0033500 1 0.056
positive regulation of jnk cascade GO:0046330 3 0.055
cellular nitrogen compound biosynthetic process GO:0044271 218 0.055
homeostatic process GO:0042592 142 0.055
androgen biosynthetic process GO:0006702 1 0.054
rna biosynthetic process GO:0032774 181 0.054
regulation of metabolic process GO:0019222 359 0.054
regulation of striated muscle contraction GO:0006942 2 0.054
regulation of cytokine production GO:0001817 3 0.053
regulation of production of molecular mediator of immune response GO:0002700 1 0.051
negative regulation of protein phosphorylation GO:0001933 4 0.051
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.051
regulation of reproductive process GO:2000241 4 0.050
establishment of localization GO:0051234 244 0.050
skeletal system morphogenesis GO:0048705 102 0.050
cellular response to lipopolysaccharide GO:0071222 3 0.050
lipid storage GO:0019915 1 0.048
androgen metabolic process GO:0008209 2 0.048
complement activation GO:0006956 3 0.048
natural killer cell mediated immunity GO:0002228 1 0.047
negative regulation of mapk cascade GO:0043409 4 0.047
regulation of protein complex assembly GO:0043254 3 0.047
larval behavior GO:0030537 5 0.046
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.046
regulation of peptidase activity GO:0052547 23 0.046
transport GO:0006810 220 0.046
immunoglobulin mediated immune response GO:0016064 3 0.045
response to stress GO:0006950 263 0.045
response to topologically incorrect protein GO:0035966 2 0.044
organic cyclic compound biosynthetic process GO:1901362 223 0.044
negative regulation of biological process GO:0048519 304 0.044
regulation of nucleocytoplasmic transport GO:0046822 2 0.043
estrogen metabolic process GO:0008210 2 0.043
fatty acid beta oxidation GO:0006635 1 0.043
peptide transport GO:0015833 1 0.042
regulation of carbohydrate metabolic process GO:0006109 4 0.042
cellular extravasation GO:0045123 1 0.042
neuron recognition GO:0008038 18 0.041
nuclear import GO:0051170 3 0.040
regulation of hormone secretion GO:0046883 2 0.040
amide biosynthetic process GO:0043604 1 0.040
interspecies interaction between organisms GO:0044419 4 0.040
protein complex localization GO:0031503 1 0.040
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.040
establishment of protein localization to organelle GO:0072594 4 0.040
response to drug GO:0042493 3 0.039
response to monosaccharide GO:0034284 3 0.039
negative regulation of reproductive process GO:2000242 3 0.039
positive regulation of leukocyte mediated immunity GO:0002705 1 0.039
positive regulation of leukocyte mediated cytotoxicity GO:0001912 1 0.038
single organism nuclear import GO:1902593 3 0.038
response to biotic stimulus GO:0009607 97 0.038
regulation of nitrogen compound metabolic process GO:0051171 251 0.037
skeletal system development GO:0001501 181 0.037
maintenance of location GO:0051235 4 0.037
cellular response to topologically incorrect protein GO:0035967 2 0.037
hormone secretion GO:0046879 2 0.037
regulation of protein transport GO:0051223 3 0.037
proteolysis GO:0006508 38 0.037
organic acid catabolic process GO:0016054 3 0.036
positive regulation of immune effector process GO:0002699 3 0.036
regulation of inflammatory response GO:0050727 2 0.036
response to alkaloid GO:0043279 2 0.035
female sex differentiation GO:0046660 4 0.035
phosphorus metabolic process GO:0006793 109 0.035
golgi vesicle transport GO:0048193 3 0.035
regulation of cellular protein catabolic process GO:1903362 1 0.034
glucose homeostasis GO:0042593 1 0.034
protein import GO:0017038 3 0.034
nucleic acid metabolic process GO:0090304 244 0.034
negative regulation of hydrolase activity GO:0051346 10 0.034
membrane invagination GO:0010324 1 0.033
plasminogen activation GO:0031639 3 0.033
organonitrogen compound metabolic process GO:1901564 74 0.033
meiotic nuclear division GO:0007126 4 0.033
fatty acid oxidation GO:0019395 1 0.033
negative regulation of nucleic acid templated transcription GO:1903507 45 0.033
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.033
locomotion GO:0040011 313 0.033
defense response GO:0006952 47 0.033
lipid catabolic process GO:0016042 4 0.033
response to glucose GO:0009749 3 0.032
regulation of ion transmembrane transporter activity GO:0032412 2 0.032
er nucleus signaling pathway GO:0006984 2 0.032
neural crest cell migration GO:0001755 42 0.032
myeloid cell differentiation GO:0030099 86 0.032
multi organism process GO:0051704 134 0.032
response to other organism GO:0051707 97 0.031
cellular macromolecule metabolic process GO:0044260 391 0.031
carbohydrate transport GO:0008643 13 0.031
hormone transport GO:0009914 2 0.031
ameboidal type cell migration GO:0001667 143 0.031
nucleocytoplasmic transport GO:0006913 4 0.031
regulation of protein targeting GO:1903533 2 0.031
single organism metabolic process GO:0044710 217 0.031
fatty acid transport GO:0015908 1 0.031
regulation of locomotion GO:0040012 55 0.030
regulation of macromolecule biosynthetic process GO:0010556 225 0.030
negative regulation of cellular catabolic process GO:0031330 3 0.029
phagocytosis GO:0006909 3 0.029
negative regulation of peptidase activity GO:0010466 10 0.029
cognition GO:0050890 1 0.029
negative regulation of translation GO:0017148 1 0.029
protein maturation GO:0051604 12 0.028
fatty acid catabolic process GO:0009062 1 0.028
system process GO:0003008 185 0.028
cellular component movement GO:0006928 335 0.028
cellular response to unfolded protein GO:0034620 2 0.028
negative regulation of protein kinase activity GO:0006469 4 0.028
regulation of hormone levels GO:0010817 21 0.028
response to bacterium GO:0009617 58 0.027
regulation of transcription dna templated GO:0006355 213 0.027
detection of external stimulus GO:0009581 24 0.027
positive regulation of cell killing GO:0031343 2 0.027
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.027
larval development GO:0002164 2 0.027
regulation of protein ubiquitination GO:0031396 3 0.027
regulation of cell cycle GO:0051726 52 0.027
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.026
zymogen activation GO:0031638 3 0.026
response to carbohydrate GO:0009743 3 0.026
carboxylic acid metabolic process GO:0019752 22 0.026
negative regulation of gene expression GO:0010629 65 0.026
regulation of transferase activity GO:0051338 16 0.026
epithelial cell differentiation GO:0030855 116 0.025
b cell mediated immunity GO:0019724 3 0.025
regulation of response to stimulus GO:0048583 269 0.025
melanin metabolic process GO:0006582 2 0.025
organic substance transport GO:0071702 58 0.025
protein secretion GO:0009306 1 0.025
somatic muscle development GO:0007525 4 0.025
cell surface receptor signaling pathway GO:0007166 325 0.025
response to hexose GO:0009746 3 0.024
regulation of rna biosynthetic process GO:2001141 213 0.024
regulation of dna templated transcription in response to stress GO:0043620 0 0.024
regulation of establishment of protein localization GO:0070201 4 0.024
positive regulation of cell cycle GO:0045787 3 0.024
cellular aromatic compound metabolic process GO:0006725 295 0.024
meiotic cell cycle process GO:1903046 3 0.024
regulation of stem cell differentiation GO:2000736 4 0.024
multicellular organismal response to stress GO:0033555 2 0.024
leukocyte mediated immunity GO:0002443 6 0.024
complement activation classical pathway GO:0006958 3 0.024
steroid hormone mediated signaling pathway GO:0043401 9 0.024
negative regulation of defense response GO:0031348 2 0.024
response to external stimulus GO:0009605 264 0.023
positive regulation of cell division GO:0051781 2 0.023
negative regulation of macromolecule metabolic process GO:0010605 76 0.023
regulation of multicellular organismal process GO:0051239 277 0.023
single organism transport GO:0044765 206 0.023
ion transmembrane transport GO:0034220 91 0.023
negative regulation of response to stimulus GO:0048585 104 0.023
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.023
blood vessel development GO:0001568 246 0.022
positive regulation of apoptotic signaling pathway GO:2001235 1 0.022
hormone mediated signaling pathway GO:0009755 9 0.022
catabolic process GO:0009056 32 0.022
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.022
negative regulation of cell communication GO:0010648 96 0.021
very long chain fatty acid biosynthetic process GO:0042761 4 0.021
organic cyclic compound metabolic process GO:1901360 301 0.021
regulation of epithelial cell proliferation GO:0050678 3 0.021
negative regulation of map kinase activity GO:0043407 2 0.021
regulation of signaling GO:0023051 235 0.021
endoplasmic reticulum unfolded protein response GO:0030968 2 0.021
single organism membrane fusion GO:0044801 2 0.021
regulation of catalytic activity GO:0050790 55 0.021
stem cell proliferation GO:0072089 4 0.021
meiosis i GO:0007127 1 0.020
cellular localization GO:0051641 97 0.020
regulation of signal transduction GO:0009966 225 0.020
positive regulation of inflammatory response GO:0050729 1 0.020
cellular response to stress GO:0033554 62 0.020
positive regulation of neuron death GO:1901216 1 0.020
programmed cell death GO:0012501 119 0.020
heart process GO:0003015 71 0.019
glial cell proliferation GO:0014009 4 0.019
cellular response to biotic stimulus GO:0071216 3 0.019
phagocytosis engulfment GO:0006911 1 0.019
cellular response to molecule of bacterial origin GO:0071219 3 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.019
positive regulation of programmed cell death GO:0043068 29 0.019
positive regulation of cellular component biogenesis GO:0044089 3 0.019
cellular response to organic substance GO:0071310 105 0.019
negative regulation of cellular process GO:0048523 283 0.019
autophagy GO:0006914 4 0.019
regulation of sodium ion transport GO:0002028 2 0.019
heterocycle metabolic process GO:0046483 290 0.019
organonitrogen compound biosynthetic process GO:1901566 47 0.019
transcription from rna polymerase ii promoter GO:0006366 80 0.019
localization of cell GO:0051674 244 0.019
heterocycle biosynthetic process GO:0018130 215 0.019
response to nutrient GO:0007584 3 0.019
regulation of binding GO:0051098 3 0.018
regulation of molecular function GO:0065009 70 0.018
hematopoietic or lymphoid organ development GO:0048534 191 0.018
defense response to bacterium GO:0042742 22 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
calcium mediated signaling GO:0019722 2 0.018
regulation of cell communication GO:0010646 232 0.018
cell motility GO:0048870 244 0.018
female gonad development GO:0008585 4 0.018
pericardium morphogenesis GO:0003344 1 0.018
cell substrate adhesion GO:0031589 4 0.018
endosomal transport GO:0016197 2 0.018
regulation of programmed cell death GO:0043067 101 0.018
regulation of primary metabolic process GO:0080090 311 0.018
interaction with host GO:0051701 4 0.017
cellular response to extracellular stimulus GO:0031668 2 0.017
nucleobase containing compound biosynthetic process GO:0034654 205 0.017
positive regulation of secretion GO:0051047 1 0.017
production of molecular mediator of immune response GO:0002440 2 0.017
post embryonic organ development GO:0048569 4 0.017
positive regulation of glucose import GO:0046326 1 0.017
antimicrobial humoral response GO:0019730 2 0.017
cell killing GO:0001906 2 0.017
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.017
organelle organization GO:0006996 227 0.017
stem cell maintenance GO:0019827 4 0.017
vacuolar transport GO:0007034 2 0.016
humoral immune response mediated by circulating immunoglobulin GO:0002455 3 0.016
cellular macromolecule biosynthetic process GO:0034645 224 0.016
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.016
renal absorption GO:0070293 1 0.016
modification of morphology or physiology of other organism GO:0035821 4 0.016
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.016
defense response to gram negative bacterium GO:0050829 8 0.016
regulation of biosynthetic process GO:0009889 250 0.016
b cell activation GO:0042113 2 0.016
cellular protein modification process GO:0006464 100 0.016
myelin assembly GO:0032288 1 0.016
cellular response to starvation GO:0009267 1 0.016
endocrine process GO:0050886 2 0.016
carbohydrate biosynthetic process GO:0016051 1 0.016
leukocyte mediated cytotoxicity GO:0001909 1 0.016
positive regulation of dna metabolic process GO:0051054 1 0.015
energy reserve metabolic process GO:0006112 2 0.015
cellular protein metabolic process GO:0044267 129 0.015
protein targeting to membrane GO:0006612 1 0.015
protein dephosphorylation GO:0006470 3 0.015
phosphate containing compound metabolic process GO:0006796 108 0.015
rna localization GO:0006403 4 0.015
regulation of macromolecule metabolic process GO:0060255 317 0.015
negative regulation of cytokine production GO:0001818 1 0.015
digestive tract morphogenesis GO:0048546 231 0.015
regulation of cell substrate adhesion GO:0010810 1 0.015
cellular response to decreased oxygen levels GO:0036294 1 0.015
protein heterooligomerization GO:0051291 1 0.015
intracellular signal transduction GO:0035556 85 0.015
response to external biotic stimulus GO:0043207 97 0.015
calcium ion import GO:0070509 4 0.015
meiotic chromosome segregation GO:0045132 3 0.015
regulation of natural killer cell mediated immunity GO:0002715 1 0.015
response to chemical GO:0042221 320 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.015
regulation of localization GO:0032879 104 0.015
mesenchymal cell differentiation GO:0048762 87 0.015
regulation of synaptic plasticity GO:0048167 1 0.015
response to unfolded protein GO:0006986 2 0.015
lipid metabolic process GO:0006629 52 0.015
positive regulation of cell substrate adhesion GO:0010811 1 0.015
cytokine mediated signaling pathway GO:0019221 7 0.015
protein homooligomerization GO:0051260 3 0.015
positive regulation of blood circulation GO:1903524 2 0.015
determination of bilateral symmetry GO:0009855 204 0.015
regulation of cysteine type endopeptidase activity GO:2000116 21 0.015
heart contraction GO:0060047 71 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.015
positive regulation of catabolic process GO:0009896 4 0.015
positive regulation of catalytic activity GO:0043085 25 0.015
regulation of circadian rhythm GO:0042752 4 0.014
positive regulation of gliogenesis GO:0014015 2 0.014
fertilization GO:0009566 3 0.014
protein import into nucleus GO:0006606 3 0.014
positive regulation of cell adhesion GO:0045785 1 0.014
morphogenesis of an epithelium GO:0002009 333 0.014
regulation of cellular ketone metabolic process GO:0010565 7 0.014
positive regulation of epithelial cell differentiation GO:0030858 2 0.014
cellular response to external stimulus GO:0071496 2 0.014
regulation of mapk cascade GO:0043408 14 0.014
sensory perception of pain GO:0019233 1 0.014
cell migration GO:0016477 237 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.014
regulation of lymphocyte mediated immunity GO:0002706 1 0.014
stem cell division GO:0017145 1 0.014
ovulation cycle GO:0042698 2 0.014
macromolecule biosynthetic process GO:0009059 227 0.014
blood vessel morphogenesis GO:0048514 216 0.014
translational initiation GO:0006413 3 0.014
long chain fatty acid biosynthetic process GO:0042759 1 0.014
cellular component assembly GO:0022607 170 0.014
hormone biosynthetic process GO:0042446 3 0.014
cellular response to hypoxia GO:0071456 1 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
response to transition metal nanoparticle GO:1990267 28 0.013
regulation of intracellular signal transduction GO:1902531 57 0.013
hepaticobiliary system development GO:0061008 98 0.013
regulation of leukocyte mediated immunity GO:0002703 1 0.013
cellular homeostasis GO:0019725 26 0.013
inner ear development GO:0048839 126 0.013
pectoral fin morphogenesis GO:0035138 29 0.013
positive regulation of cell activation GO:0050867 1 0.013
transcription dna templated GO:0006351 181 0.013
regulation of myotube differentiation GO:0010830 2 0.013
monosaccharide transport GO:0015749 6 0.013
regulation of systemic arterial blood pressure GO:0003073 1 0.013
response to salt stress GO:0009651 10 0.013
negative regulation of multi organism process GO:0043901 3 0.013
positive regulation of epithelial cell proliferation GO:0050679 1 0.013
positive regulation of secretion by cell GO:1903532 1 0.013
stem cell differentiation GO:0048863 117 0.013
regulation of transport GO:0051049 45 0.013
regulation of transmembrane transporter activity GO:0022898 2 0.013
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.013
amine metabolic process GO:0009308 2 0.013
regulation of transporter activity GO:0032409 2 0.013
cellular response to drug GO:0035690 1 0.013
immune system development GO:0002520 191 0.013
positive regulation of cytoskeleton organization GO:0051495 3 0.013
gastrulation GO:0007369 208 0.013
l amino acid transport GO:0015807 1 0.013
membrane lipid biosynthetic process GO:0046467 2 0.012
detection of stimulus GO:0051606 29 0.012
guanosine containing compound metabolic process GO:1901068 4 0.012
immunoglobulin production GO:0002377 1 0.012
nitric oxide biosynthetic process GO:0006809 2 0.012
adherens junction organization GO:0034332 4 0.012
internal protein amino acid acetylation GO:0006475 2 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
fatty acid biosynthetic process GO:0006633 4 0.012
regulation of translational initiation GO:0006446 1 0.012
sleep GO:0030431 1 0.012
regulation of nucleic acid templated transcription GO:1903506 213 0.012
peptidyl serine phosphorylation GO:0018105 1 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
regulation of glial cell proliferation GO:0060251 4 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
lymphocyte mediated immunity GO:0002449 5 0.012
mesenchyme development GO:0060485 127 0.012
microtubule organizing center organization GO:0031023 1 0.012
establishment of localization in cell GO:0051649 77 0.012
protein modification process GO:0036211 100 0.012
regulation of muscle contraction GO:0006937 3 0.012
regulation of protein metabolic process GO:0051246 56 0.012
ovulation cycle process GO:0022602 2 0.012
cellular component disassembly GO:0022411 1 0.012
cellular response to endogenous stimulus GO:0071495 68 0.012
regulation of skeletal muscle tissue development GO:0048641 4 0.012
mesoderm development GO:0007498 88 0.012
organelle membrane fusion GO:0090174 2 0.011
immune system process GO:0002376 241 0.011
morphogenesis of an epithelial fold GO:0060571 1 0.011
negative regulation of protein import into nucleus GO:0042308 2 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.011
regulation of cell shape GO:0008360 1 0.011
homeostasis of number of cells within a tissue GO:0048873 4 0.011
sphingolipid biosynthetic process GO:0030148 2 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
aromatic compound biosynthetic process GO:0019438 217 0.011
smooth muscle contraction GO:0006939 2 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
regulation of protein binding GO:0043393 3 0.011
neurological system process GO:0050877 62 0.011
protein localization to plasma membrane GO:0072659 1 0.011
regulation of response to stress GO:0080134 36 0.011
homeostasis of number of cells GO:0048872 62 0.011
positive regulation of myeloid cell differentiation GO:0045639 2 0.011
positive regulation of epithelial cell migration GO:0010634 2 0.011
cellular response to nutrient levels GO:0031669 2 0.011
multicellular organismal metabolic process GO:0044236 2 0.011
regulation of cellular component movement GO:0051270 55 0.011
macromolecule modification GO:0043412 111 0.011
protein polyubiquitination GO:0000209 4 0.011
neuroblast proliferation GO:0007405 2 0.011
negative regulation of protein localization to nucleus GO:1900181 2 0.011
long chain fatty acid metabolic process GO:0001676 1 0.011
regulation of multicellular organismal development GO:2000026 223 0.011
cell proliferation involved in heart morphogenesis GO:0061323 2 0.011
regulation of nik nf kappab signaling GO:1901222 1 0.011
very long chain fatty acid metabolic process GO:0000038 4 0.011
protein activation cascade GO:0072376 6 0.011
centrosome organization GO:0051297 1 0.011
p38mapk cascade GO:0038066 1 0.011
dorsal ventral pattern formation GO:0009953 125 0.010
proteasomal protein catabolic process GO:0010498 2 0.010
regulation of stem cell proliferation GO:0072091 2 0.010
light adaption GO:0036367 1 0.010
regulation of cell death GO:0010941 103 0.010
regulation of circadian sleep wake cycle GO:0042749 1 0.010
cellular response to radiation GO:0071478 4 0.010
death GO:0016265 121 0.010
nephron development GO:0072006 31 0.010
water homeostasis GO:0030104 4 0.010
regulation of cellular response to oxidative stress GO:1900407 2 0.010
adult behavior GO:0030534 2 0.010
organic substance catabolic process GO:1901575 28 0.010
neural crest cell differentiation GO:0014033 72 0.010
regulation of blood circulation GO:1903522 32 0.010
single organism carbohydrate metabolic process GO:0044723 12 0.010
single organism biosynthetic process GO:0044711 71 0.010
ubiquitin dependent protein catabolic process GO:0006511 3 0.010
fatty acid elongation GO:0030497 1 0.010
phototransduction GO:0007602 2 0.010

pcsk7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
sensory system disease DOID:0050155 0 0.017
eye and adnexa disease DOID:1492 0 0.017
nervous system disease DOID:863 0 0.017
eye disease DOID:5614 0 0.017
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
cardiovascular system disease DOID:1287 0 0.013