Danio rerio

0 known processes

pde6a

phosphodiesterase 6A, cGMP-specific, rod, alpha

(Aliases: si:bz1d10.3,si:rp71-1d10.3)

pde6a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
eye development GO:0001654 277 0.187
Mouse
camera type eye development GO:0043010 222 0.148
Mouse
generation of neurons GO:0048699 385 0.116
signal transduction GO:0007165 455 0.090
response to abiotic stimulus GO:0009628 122 0.088
larval development GO:0002164 2 0.079
retina development in camera type eye GO:0060041 146 0.076
Mouse
phagocytosis GO:0006909 3 0.072
sensory organ development GO:0007423 393 0.067
Mouse
system process GO:0003008 185 0.065
aging GO:0007568 2 0.065
neurological system process GO:0050877 62 0.057
single organism transport GO:0044765 206 0.055
detection of stimulus GO:0051606 29 0.052
response to light stimulus GO:0009416 46 0.052
blood vessel development GO:0001568 246 0.052
small molecule metabolic process GO:0044281 77 0.052
Human
entrainment of circadian clock GO:0009649 2 0.049
detection of abiotic stimulus GO:0009582 24 0.046
sensory perception of chemical stimulus GO:0007606 3 0.046
organonitrogen compound metabolic process GO:1901564 74 0.043
Human
stem cell proliferation GO:0072089 4 0.042
response to external stimulus GO:0009605 264 0.040
cell surface receptor signaling pathway GO:0007166 325 0.040
transport GO:0006810 220 0.040
cellular amine metabolic process GO:0044106 2 0.039
regulation of establishment of protein localization GO:0070201 4 0.039
regulation of response to stimulus GO:0048583 269 0.039
regulation of protein transport GO:0051223 3 0.039
adult behavior GO:0030534 2 0.038
camera type eye morphogenesis GO:0048593 108 0.038
neurotransmitter secretion GO:0007269 2 0.038
detection of external stimulus GO:0009581 24 0.038
response to chemical GO:0042221 320 0.037
positive regulation of map kinase activity GO:0043406 3 0.037
eye photoreceptor cell differentiation GO:0001754 45 0.036
membrane invagination GO:0010324 1 0.036
maintenance of location GO:0051235 4 0.036
neurotransmitter transport GO:0006836 2 0.035
regulation of biological quality GO:0065008 263 0.035
Human
neuron differentiation GO:0030182 353 0.035
immune system process GO:0002376 241 0.034
positive regulation of transport GO:0051050 2 0.034
response to radiation GO:0009314 51 0.033
regulation of cellular amine metabolic process GO:0033238 0 0.033
regulation of circadian rhythm GO:0042752 4 0.033
single organism localization GO:1902578 225 0.033
cellular amino acid metabolic process GO:0006520 7 0.033
phototransduction GO:0007602 2 0.033
organic acid metabolic process GO:0006082 31 0.033
ion transport GO:0006811 114 0.033
guanosine containing compound metabolic process GO:1901068 4 0.032
Human
transmission of nerve impulse GO:0019226 19 0.032
amine metabolic process GO:0009308 2 0.031
cortical cytoskeleton organization GO:0030865 1 0.031
blood vessel morphogenesis GO:0048514 216 0.031
cell morphogenesis GO:0000902 289 0.031
sensory organ morphogenesis GO:0090596 200 0.030
tube morphogenesis GO:0035239 349 0.030
response to stress GO:0006950 263 0.030
cellular component movement GO:0006928 335 0.030
carboxylic acid metabolic process GO:0019752 22 0.029
regulation of multicellular organismal development GO:2000026 223 0.029
nucleocytoplasmic transport GO:0006913 4 0.029
regulation of nucleoside metabolic process GO:0009118 2 0.029
phagocytosis engulfment GO:0006911 1 0.028
hemopoiesis GO:0030097 183 0.028
cellular nitrogen compound metabolic process GO:0034641 290 0.028
Human
digestive tract morphogenesis GO:0048546 231 0.028
regulation of purine nucleotide catabolic process GO:0033121 2 0.028
regulation of cytoplasmic transport GO:1903649 4 0.027
multicellular organism growth GO:0035264 4 0.027
vasculature development GO:0001944 278 0.027
response to drug GO:0042493 3 0.026
cellular component morphogenesis GO:0032989 336 0.026
detection of light stimulus GO:0009583 12 0.026
cytokinesis GO:0000910 3 0.026
regulation of cellular ketone metabolic process GO:0010565 7 0.025
regulation of intracellular protein transport GO:0033157 3 0.025
regulation of nucleotide catabolic process GO:0030811 2 0.025
guanosine containing compound catabolic process GO:1901069 2 0.025
regulation of metal ion transport GO:0010959 4 0.025
regulation of multicellular organism growth GO:0040014 4 0.025
regulation of protein complex assembly GO:0043254 3 0.024
immune system development GO:0002520 191 0.024
cell projection organization GO:0030030 284 0.024
gtp metabolic process GO:0046039 4 0.024
response to wounding GO:0009611 116 0.024
heart looping GO:0001947 94 0.024
negative regulation of protein phosphorylation GO:0001933 4 0.023
mitochondrion organization GO:0007005 4 0.023
cell migration involved in gastrulation GO:0042074 79 0.023
nitrogen compound metabolic process GO:0006807 319 0.023
Human
response to amino acid GO:0043200 2 0.023
establishment of localization GO:0051234 244 0.023
eye morphogenesis GO:0048592 144 0.023
action potential GO:0001508 19 0.022
visual perception GO:0007601 17 0.022
regulation of cell communication GO:0010646 232 0.022
regulation of gtp catabolic process GO:0033124 2 0.022
meiotic nuclear division GO:0007126 4 0.022
cell migration GO:0016477 237 0.022
morphogenesis of an epithelium GO:0002009 333 0.022
positive regulation of biological process GO:0048518 253 0.022
regulation of guanylate cyclase activity GO:0031282 6 0.022
phosphate containing compound metabolic process GO:0006796 108 0.022
Human
inositol lipid mediated signaling GO:0048017 2 0.021
regulation of signaling GO:0023051 235 0.021
dopamine metabolic process GO:0042417 2 0.021
embryonic organ development GO:0048568 381 0.021
regulation of nucleocytoplasmic transport GO:0046822 2 0.021
nuclear transport GO:0051169 4 0.021
regulation of binding GO:0051098 3 0.021
locomotion GO:0040011 313 0.021
gtp catabolic process GO:0006184 2 0.021
cation transmembrane transport GO:0098655 65 0.021
regulation of signal transduction GO:0009966 225 0.021
hematopoietic or lymphoid organ development GO:0048534 191 0.021
cell projection morphogenesis GO:0048858 244 0.021
transmembrane transport GO:0055085 120 0.021
chemosensory behavior GO:0007635 1 0.021
neuron projection development GO:0031175 180 0.021
positive regulation of cgmp biosynthetic process GO:0030828 6 0.021
regulation of reproductive process GO:2000241 4 0.020
digestive system development GO:0055123 289 0.020
axon ensheathment in central nervous system GO:0032291 2 0.020
regulation of neurogenesis GO:0050767 87 0.020
organic cyclic compound metabolic process GO:1901360 301 0.020
Human
cell motility GO:0048870 244 0.020
regulation of dendrite morphogenesis GO:0048814 3 0.020
convergent extension GO:0060026 118 0.020
angiogenesis GO:0001525 158 0.020
actin polymerization or depolymerization GO:0008154 2 0.019
sensory perception GO:0007600 39 0.019
cell growth GO:0016049 57 0.019
establishment of blood brain barrier GO:0060856 2 0.019
protein polymerization GO:0051258 4 0.019
cellular response to external stimulus GO:0071496 2 0.019
localization of cell GO:0051674 244 0.019
cellular component disassembly GO:0022411 1 0.019
regulation of ion transmembrane transporter activity GO:0032412 2 0.019
negative regulation of biological process GO:0048519 304 0.019
olfactory lobe development GO:0021988 4 0.019
digestive tract development GO:0048565 265 0.019
response to uv GO:0009411 3 0.019
regulation of synapse organization GO:0050807 3 0.018
stem cell division GO:0017145 1 0.018
regulation of blood vessel size GO:0050880 2 0.018
neuron neuron synaptic transmission GO:0007270 1 0.018
locomotor rhythm GO:0045475 3 0.018
cortical actin cytoskeleton organization GO:0030866 1 0.018
catecholamine metabolic process GO:0006584 2 0.018
regulation of neuron projection development GO:0010975 40 0.018
regulation of sequestering of calcium ion GO:0051282 4 0.018
heterocycle metabolic process GO:0046483 290 0.017
Human
catechol containing compound metabolic process GO:0009712 2 0.017
regulation of cell development GO:0060284 100 0.017
oxidation reduction process GO:0055114 41 0.017
synaptic vesicle transport GO:0048489 1 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.017
regulation of postsynaptic membrane potential GO:0060078 1 0.017
chordate embryonic development GO:0043009 271 0.017
cellular component assembly GO:0022607 170 0.017
negative regulation of defense response GO:0031348 2 0.017
neuronal action potential GO:0019228 18 0.017
regulation of nitrogen compound metabolic process GO:0051171 251 0.017
organelle organization GO:0006996 227 0.017
regulation of transmembrane transporter activity GO:0022898 2 0.017
establishment of protein localization to organelle GO:0072594 4 0.017
meiotic cell cycle process GO:1903046 3 0.017
response to endogenous stimulus GO:0009719 83 0.017
phosphorus metabolic process GO:0006793 109 0.017
Human
neuroblast proliferation GO:0007405 2 0.017
multi organism process GO:0051704 134 0.017
protein modification process GO:0036211 100 0.016
positive regulation of cell cycle GO:0045787 3 0.016
photoperiodism GO:0009648 11 0.016
purine nucleoside monophosphate catabolic process GO:0009128 4 0.016
cell part morphogenesis GO:0032990 246 0.016
gastrulation GO:0007369 208 0.016
behavior GO:0007610 74 0.016
regulation of synaptic plasticity GO:0048167 1 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
regulation of inflammatory response GO:0050727 2 0.016
ameboidal type cell migration GO:0001667 143 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.016
negative regulation of sequestering of calcium ion GO:0051283 4 0.016
regulation of neurotransmitter transport GO:0051588 1 0.016
regulation of localization GO:0032879 104 0.016
regulation of dendrite development GO:0050773 3 0.016
negative regulation of cellular process GO:0048523 283 0.016
developmental growth involved in morphogenesis GO:0060560 86 0.016
positive regulation of catabolic process GO:0009896 4 0.016
regulation of metabolic process GO:0019222 359 0.015
camera type eye photoreceptor cell differentiation GO:0060219 19 0.015
photoreceptor cell differentiation GO:0046530 55 0.015
embryonic organ morphogenesis GO:0048562 274 0.015
regulation of cell differentiation GO:0045595 142 0.015
response to organic substance GO:0010033 153 0.015
embryonic heart tube morphogenesis GO:0003143 108 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
calcium mediated signaling GO:0019722 2 0.015
heart development GO:0007507 313 0.015
regulation of anatomical structure morphogenesis GO:0022603 130 0.015
regulation of transporter activity GO:0032409 2 0.015
rna localization GO:0006403 4 0.015
atp catabolic process GO:0006200 4 0.015
growth GO:0040007 174 0.015
protein homooligomerization GO:0051260 3 0.015
establishment of synaptic vesicle localization GO:0097480 1 0.015
regulation of cellular component organization GO:0051128 86 0.015
cell fate commitment GO:0045165 99 0.014
developmental growth GO:0048589 166 0.014
single organism metabolic process GO:0044710 217 0.014
Human
regulation of cell projection organization GO:0031344 44 0.014
alpha amino acid metabolic process GO:1901605 3 0.014
cellular aldehyde metabolic process GO:0006081 4 0.014
regulation of tube size GO:0035150 2 0.014
oxoacid metabolic process GO:0043436 31 0.014
positive regulation of protein complex assembly GO:0031334 2 0.014
embryonic heart tube development GO:0035050 133 0.014
cellular macromolecule metabolic process GO:0044260 391 0.014
rho protein signal transduction GO:0007266 5 0.014
cellular aromatic compound metabolic process GO:0006725 295 0.014
Human
olfactory bulb development GO:0021772 4 0.014
positive regulation of cell communication GO:0010647 56 0.014
organic substance transport GO:0071702 58 0.014
macromolecular complex disassembly GO:0032984 1 0.014
neuron development GO:0048666 262 0.014
positive regulation of signal transduction GO:0009967 56 0.014
ribonucleoside monophosphate catabolic process GO:0009158 4 0.014
cellular component assembly involved in morphogenesis GO:0010927 107 0.014
synaptic growth at neuromuscular junction GO:0051124 2 0.014
protein targeting to nucleus GO:0044744 3 0.013
regulation of neuron differentiation GO:0045664 56 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
multicellular organismal signaling GO:0035637 22 0.013
regulation of gtpase activity GO:0043087 2 0.013
regulation of protein complex disassembly GO:0043244 1 0.013
regulation of multicellular organismal process GO:0051239 277 0.013
organonitrogen compound biosynthetic process GO:1901566 47 0.013
regulation of cellular component movement GO:0051270 55 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
regulation of locomotion GO:0040012 55 0.013
cellular response to radiation GO:0071478 4 0.013
protein complex disassembly GO:0043241 1 0.013
cellular ketone metabolic process GO:0042180 11 0.013
regulation of calcium ion transport GO:0051924 2 0.013
regulation of protein polymerization GO:0032271 2 0.013
membrane hyperpolarization GO:0060081 1 0.013
sleep GO:0030431 1 0.013
activation of mapk activity GO:0000187 3 0.013
phototransduction visible light GO:0007603 2 0.013
muscle structure development GO:0061061 196 0.013
establishment of endothelial barrier GO:0061028 3 0.012
inorganic cation transmembrane transport GO:0098662 50 0.012
glial cell development GO:0021782 20 0.012
anterior posterior pattern specification GO:0009952 152 0.012
regulation of membrane potential GO:0042391 23 0.012
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.012
regulation of cytokine production GO:0001817 3 0.012
nuclear import GO:0051170 3 0.012
negative regulation of protein complex assembly GO:0031333 1 0.012
retina morphogenesis in camera type eye GO:0060042 79 0.012
response to amphetamine GO:0001975 1 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
neuron projection morphogenesis GO:0048812 161 0.012
inorganic anion transport GO:0015698 25 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
actin filament polymerization GO:0030041 2 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
maternal determination of anterior posterior axis embryo GO:0008358 4 0.012
determination of bilateral symmetry GO:0009855 204 0.012
single organism organelle organization GO:1902589 199 0.012
developmental programmed cell death GO:0010623 4 0.012
negative regulation of secretion GO:0051048 2 0.012
cellular localization GO:0051641 97 0.011
regulation of nervous system development GO:0051960 90 0.011
regulation of cell activation GO:0050865 1 0.011
apical junction assembly GO:0043297 1 0.011
multicellular organismal response to stress GO:0033555 2 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
response to vitamin GO:0033273 3 0.011
gliogenesis GO:0042063 45 0.011
regulation of receptor activity GO:0010469 2 0.011
cellular transition metal ion homeostasis GO:0046916 3 0.011
protein localization to plasma membrane GO:0072659 1 0.011
cell substrate adhesion GO:0031589 4 0.011
regulation of translational initiation GO:0006446 1 0.011
cellular response to extracellular stimulus GO:0031668 2 0.011
mesenchymal cell differentiation GO:0048762 87 0.011
cellular protein metabolic process GO:0044267 129 0.011
protein import GO:0017038 3 0.011
establishment of melanosome localization GO:0032401 19 0.011
synaptic vesicle localization GO:0097479 1 0.011
gas transport GO:0015669 3 0.011
heart morphogenesis GO:0003007 156 0.011
positive regulation of cellular component biogenesis GO:0044089 3 0.011
endocrine process GO:0050886 2 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.011
response to topologically incorrect protein GO:0035966 2 0.011
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.011
pyruvate metabolic process GO:0006090 1 0.011
protein metabolic process GO:0019538 183 0.011
nuclear export GO:0051168 1 0.011
head development GO:0060322 303 0.011
regulation of purine nucleotide metabolic process GO:1900542 17 0.011
ras protein signal transduction GO:0007265 7 0.011
positive regulation of signaling GO:0023056 56 0.011
homeostatic process GO:0042592 142 0.011
Human
organelle localization GO:0051640 49 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.011
positive regulation of guanylate cyclase activity GO:0031284 6 0.011
single organism cellular localization GO:1902580 46 0.011
spermatid development GO:0007286 2 0.011
cognition GO:0050890 1 0.010
protein import into nucleus GO:0006606 3 0.010
regulation of cell migration GO:0030334 40 0.010
small gtpase mediated signal transduction GO:0007264 8 0.010
negative regulation of protein kinase activity GO:0006469 4 0.010
regulation of jak stat cascade GO:0046425 3 0.010
establishment of localization in cell GO:0051649 77 0.010
organic substance biosynthetic process GO:1901576 289 0.010
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.010
adherens junction assembly GO:0034333 1 0.010
fatty acid transport GO:0015908 1 0.010
synaptic vesicle endocytosis GO:0048488 1 0.010
regulation of protein depolymerization GO:1901879 1 0.010
fat soluble vitamin metabolic process GO:0006775 4 0.010
establishment of organelle localization GO:0051656 45 0.010
positive regulation of striated muscle tissue development GO:0045844 1 0.010
long chain fatty acid transport GO:0015909 1 0.010
absorption of visible light GO:0016038 2 0.010
protein secretion GO:0009306 1 0.010
positive regulation of cell division GO:0051781 2 0.010
positive regulation of response to stimulus GO:0048584 80 0.010
gastrulation with mouth forming second GO:0001702 44 0.010
sequestering of calcium ion GO:0051208 3 0.010
single fertilization GO:0007338 3 0.010
cytoskeleton dependent cytokinesis GO:0061640 3 0.010
lipid storage GO:0019915 1 0.010
sensory system development GO:0048880 76 0.010
kupffer s vesicle development GO:0070121 50 0.010
endomembrane system organization GO:0010256 13 0.010
posterior lateral line system development GO:0048915 46 0.010

pde6a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
Human
nervous system disease DOID:863 0 0.045
Human
eye disease DOID:5614 0 0.022
Human
eye and adnexa disease DOID:1492 0 0.022
Human
sensory system disease DOID:0050155 0 0.022
Human
inherited metabolic disorder DOID:655 0 0.012
disease of metabolism DOID:0014667 0 0.012
retinal disease DOID:5679 0 0.012
Human