Danio rerio

0 known processes

pde6h

phosphodiesterase 6H, cGMP-specific, cone, gamma

(Aliases: zgc:73310,MGC73310)

pde6h biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
signal transduction GO:0007165 455 0.224
Mouse
response to external stimulus GO:0009605 264 0.195
g protein coupled receptor signaling pathway GO:0007186 74 0.176
Mouse
vasculature development GO:0001944 278 0.150
phototransduction GO:0007602 2 0.117
regulation of metabolic process GO:0019222 359 0.103
Mouse
response to abiotic stimulus GO:0009628 122 0.101
blood vessel morphogenesis GO:0048514 216 0.092
tube morphogenesis GO:0035239 349 0.089
blood vessel development GO:0001568 246 0.087
stem cell division GO:0017145 1 0.085
er nucleus signaling pathway GO:0006984 2 0.073
guanosine containing compound metabolic process GO:1901068 4 0.071
photoperiodism GO:0009648 11 0.069
maintenance of location GO:0051235 4 0.065
gas transport GO:0015669 3 0.063
regulation of nucleotide catabolic process GO:0030811 2 0.063
cell morphogenesis GO:0000902 289 0.062
light induced release of internally sequestered calcium ion GO:0008377 1 0.059
establishment of blood brain barrier GO:0060856 2 0.057
cellular ketone metabolic process GO:0042180 11 0.057
absorption of visible light GO:0016038 2 0.054
light absorption GO:0016037 2 0.054
regulation of purine nucleotide catabolic process GO:0033121 2 0.054
gtp catabolic process GO:0006184 2 0.053
rhodopsin mediated signaling pathway GO:0016056 1 0.049
establishment of endothelial barrier GO:0061028 3 0.049
nuclear export GO:0051168 1 0.046
organic acid metabolic process GO:0006082 31 0.045
detection of stimulus GO:0051606 29 0.044
detection of external stimulus GO:0009581 24 0.044
small gtpase mediated signal transduction GO:0007264 8 0.042
negative regulation of protein phosphorylation GO:0001933 4 0.041
epiboly GO:0090504 41 0.040
detection of abiotic stimulus GO:0009582 24 0.040
regulation of gtp catabolic process GO:0033124 2 0.040
regulation of sequestering of calcium ion GO:0051282 4 0.039
detection of visible light GO:0009584 12 0.039
cortical cytoskeleton organization GO:0030865 1 0.039
guanosine containing compound catabolic process GO:1901069 2 0.038
visual perception GO:0007601 17 0.037
negative regulation of cellular process GO:0048523 283 0.036
system process GO:0003008 185 0.035
regulation of macromolecule metabolic process GO:0060255 317 0.034
Mouse
detection of light stimulus GO:0009583 12 0.034
convergent extension GO:0060026 118 0.034
carboxylic acid metabolic process GO:0019752 22 0.033
stem cell proliferation GO:0072089 4 0.032
phosphorus metabolic process GO:0006793 109 0.032
Mouse
nucleocytoplasmic transport GO:0006913 4 0.032
transmission of nerve impulse GO:0019226 19 0.031
regulation of response to stimulus GO:0048583 269 0.031
Mouse
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.031
regulation of circadian sleep wake cycle GO:0042749 1 0.030
larval development GO:0002164 2 0.030
gtp metabolic process GO:0046039 4 0.030
cortical actin cytoskeleton organization GO:0030866 1 0.030
neuronal action potential GO:0019228 18 0.030
regulation of nucleoside metabolic process GO:0009118 2 0.030
negative regulation of cell cell adhesion mediated by cadherin GO:2000048 2 0.030
sensory organ development GO:0007423 393 0.029
single organism metabolic process GO:0044710 217 0.029
Mouse
regulation of primary metabolic process GO:0080090 311 0.029
Mouse
regulation of cellular ketone metabolic process GO:0010565 7 0.029
nitrogen compound metabolic process GO:0006807 319 0.028
cell surface receptor signaling pathway GO:0007166 325 0.028
Mouse
homeostatic process GO:0042592 142 0.028
lipid storage GO:0019915 1 0.027
eye photoreceptor cell differentiation GO:0001754 45 0.027
amine metabolic process GO:0009308 2 0.027
negative regulation of biological process GO:0048519 304 0.027
regulation of gtpase activity GO:0043087 2 0.027
axon ensheathment in central nervous system GO:0032291 2 0.026
regulation of signal transduction GO:0009966 225 0.026
Mouse
digestive tract development GO:0048565 265 0.026
regulation of cellular amine metabolic process GO:0033238 0 0.026
organonitrogen compound metabolic process GO:1901564 74 0.025
positive regulation of cellular catabolic process GO:0031331 3 0.025
aging GO:0007568 2 0.024
cgmp biosynthetic process GO:0006182 7 0.024
phosphate containing compound metabolic process GO:0006796 108 0.024
Mouse
inositol lipid mediated signaling GO:0048017 2 0.024
intracellular signal transduction GO:0035556 85 0.023
Mouse
cellular amino acid metabolic process GO:0006520 7 0.023
ras protein signal transduction GO:0007265 7 0.023
cellular nitrogen compound metabolic process GO:0034641 290 0.022
gene expression GO:0010467 252 0.022
activation of mapk activity GO:0000187 3 0.022
Mouse
heterocycle metabolic process GO:0046483 290 0.022
single fertilization GO:0007338 3 0.021
nuclear transport GO:0051169 4 0.021
regulation of nitrogen compound metabolic process GO:0051171 251 0.021
positive regulation of catabolic process GO:0009896 4 0.021
regulation of phosphorus metabolic process GO:0051174 43 0.021
Mouse
positive regulation of map kinase activity GO:0043406 3 0.020
Mouse
cellular response to light stimulus GO:0071482 4 0.020
regulation of skeletal muscle tissue development GO:0048641 4 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
digestive tract morphogenesis GO:0048546 231 0.019
purine nucleotide metabolic process GO:0006163 27 0.019
sleep GO:0030431 1 0.018
organic cyclic compound metabolic process GO:1901360 301 0.018
positive regulation of lipid metabolic process GO:0045834 1 0.018
neural retina development GO:0003407 49 0.018
oxoacid metabolic process GO:0043436 31 0.018
generation of neurons GO:0048699 385 0.018
embryonic organ morphogenesis GO:0048562 274 0.018
angiogenesis GO:0001525 158 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
small molecule metabolic process GO:0044281 77 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
regulation of biological quality GO:0065008 263 0.018
cellular component morphogenesis GO:0032989 336 0.018
sequestering of calcium ion GO:0051208 3 0.017
cellular response to radiation GO:0071478 4 0.017
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
positive regulation of response to stimulus GO:0048584 80 0.017
Mouse
protein targeting to nucleus GO:0044744 3 0.017
multicellular organismal signaling GO:0035637 22 0.017
regulation of intracellular protein transport GO:0033157 3 0.017
neuron projection morphogenesis GO:0048812 161 0.017
sequestering of metal ion GO:0051238 3 0.017
positive regulation of cell cycle GO:0045787 3 0.017
regulation of molecular function GO:0065009 70 0.017
Mouse
cell growth GO:0016049 57 0.017
establishment of localization GO:0051234 244 0.017
sensory perception GO:0007600 39 0.017
regulation of cell communication GO:0010646 232 0.016
Mouse
immune system process GO:0002376 241 0.016
positive regulation of camp biosynthetic process GO:0030819 2 0.016
response to uv GO:0009411 3 0.016
regulation of intracellular ph GO:0051453 1 0.016
regulation of protein polymerization GO:0032271 2 0.016
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.016
endothelial cell development GO:0001885 12 0.016
cellular amine metabolic process GO:0044106 2 0.016
cellular response to unfolded protein GO:0034620 2 0.015
detection of stimulus involved in sensory perception GO:0050906 21 0.015
ph reduction GO:0045851 1 0.015
fertilization GO:0009566 3 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
retina development in camera type eye GO:0060041 146 0.015
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.015
cellular response to topologically incorrect protein GO:0035967 2 0.015
morphogenesis of an epithelium GO:0002009 333 0.015
modification dependent protein catabolic process GO:0019941 3 0.015
regulation of cellular metabolic process GO:0031323 320 0.015
Mouse
single organism biosynthetic process GO:0044711 71 0.015
neuron differentiation GO:0030182 353 0.014
regulation of ph GO:0006885 3 0.014
negative regulation of sequestering of calcium ion GO:0051283 4 0.014
eye development GO:0001654 277 0.014
growth GO:0040007 174 0.014
response to hexose GO:0009746 3 0.014
regulation of protein transport GO:0051223 3 0.014
cellular macromolecule metabolic process GO:0044260 391 0.014
Mouse
pigmentation GO:0043473 85 0.014
hemopoiesis GO:0030097 183 0.014
axonogenesis GO:0007409 152 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.014
vitamin a biosynthetic process GO:0035238 1 0.013
cellular protein metabolic process GO:0044267 129 0.013
Mouse
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.013
protein homooligomerization GO:0051260 3 0.013
regulation of neurological system process GO:0031644 2 0.013
negative regulation of defense response GO:0031348 2 0.013
gastrulation GO:0007369 208 0.013
neurotransmitter secretion GO:0007269 2 0.013
ribose phosphate metabolic process GO:0019693 27 0.013
regulation of phosphate metabolic process GO:0019220 43 0.013
Mouse
exocytosis GO:0006887 1 0.013
proteasomal protein catabolic process GO:0010498 2 0.013
enzyme linked receptor protein signaling pathway GO:0007167 106 0.013
Mouse
inorganic cation transmembrane transport GO:0098662 50 0.013
regulation of localization GO:0032879 104 0.013
regulation of response to nutrient levels GO:0032107 1 0.012
inorganic anion transport GO:0015698 25 0.012
response to unfolded protein GO:0006986 2 0.012
sensory organ morphogenesis GO:0090596 200 0.012
camera type eye development GO:0043010 222 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
cell aging GO:0007569 2 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
sensory perception of light stimulus GO:0050953 19 0.012
gastrulation with mouth forming second GO:0001702 44 0.012
cellular response to starvation GO:0009267 1 0.012
organelle organization GO:0006996 227 0.012
fat soluble vitamin biosynthetic process GO:0042362 2 0.012
hematopoietic or lymphoid organ development GO:0048534 191 0.012
cyclic nucleotide biosynthetic process GO:0009190 18 0.012
carbohydrate derivative metabolic process GO:1901135 61 0.012
retina vasculature development in camera type eye GO:0061298 2 0.012
regulation of cell activation GO:0050865 1 0.012
regulation of nucleotide metabolic process GO:0006140 17 0.011
protein modification process GO:0036211 100 0.011
Mouse
negative regulation of response to stimulus GO:0048585 104 0.011
cellular response to decreased oxygen levels GO:0036294 1 0.011
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.011
calcium mediated signaling GO:0019722 2 0.011
response to radiation GO:0009314 51 0.011
phagocytosis GO:0006909 3 0.011
regulation of membrane potential GO:0042391 23 0.011
regulation of cell aging GO:0090342 1 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
regulation of stem cell proliferation GO:0072091 2 0.011
cellular protein modification process GO:0006464 100 0.010
Mouse
vascular endothelial growth factor receptor signaling pathway GO:0048010 13 0.010
cell migration involved in gastrulation GO:0042074 79 0.010
cellular response to oxygen levels GO:0071453 1 0.010
regulation of protein complex assembly GO:0043254 3 0.010
phototransduction visible light GO:0007603 2 0.010
cellular component movement GO:0006928 335 0.010
taxis GO:0042330 109 0.010
cytokinesis GO:0000910 3 0.010
skeletal system development GO:0001501 181 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.010
Mouse
regulation of signaling GO:0023051 235 0.010
Mouse
circadian sleep wake cycle process GO:0022410 2 0.010
neurological system process GO:0050877 62 0.010
calcium ion dependent exocytosis GO:0017156 1 0.010
neuron projection development GO:0031175 180 0.010

pde6h disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.010
disease of anatomical entity DOID:7 0 0.010