Danio rerio

17 known processes

pdgfrb2

platelet derived growth factor receptor beta 2

pdgfrb2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
blood vessel morphogenesis GO:0048514 216 0.512
blood vessel development GO:0001568 246 0.384
sprouting angiogenesis GO:0002040 53 0.368
angiogenesis GO:0001525 158 0.326
vasculature development GO:0001944 278 0.285
camera type eye development GO:0043010 222 0.243
sensory organ development GO:0007423 393 0.229
specification of symmetry GO:0009799 204 0.212
morphogenesis of an epithelium GO:0002009 333 0.179
digestive tract development GO:0048565 265 0.122
eye development GO:0001654 277 0.111
embryonic organ development GO:0048568 381 0.108
cell motility GO:0048870 244 0.100
cell surface receptor signaling pathway GO:0007166 325 0.098
chordate embryonic development GO:0043009 271 0.098
cell migration involved in gastrulation GO:0042074 79 0.098
ameboidal type cell migration GO:0001667 143 0.092
heart development GO:0007507 313 0.088
response to carbohydrate GO:0009743 3 0.087
rna metabolic process GO:0016070 219 0.083
digestive system development GO:0055123 289 0.082
regulation of tube size GO:0035150 2 0.082
sensory organ morphogenesis GO:0090596 200 0.078
neuroblast proliferation GO:0007405 2 0.077
cellular component movement GO:0006928 335 0.076
cognition GO:0050890 1 0.075
convergent extension GO:0060026 118 0.074
brain development GO:0007420 293 0.071
regulation of signal transduction GO:0009966 225 0.071
negative regulation of signaling GO:0023057 96 0.068
regulation of nucleocytoplasmic transport GO:0046822 2 0.067
retina development in camera type eye GO:0060041 146 0.066
eye morphogenesis GO:0048592 144 0.062
tube morphogenesis GO:0035239 349 0.061
positive regulation of glucose transport GO:0010828 1 0.061
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.061
regulation of blood vessel size GO:0050880 2 0.060
nitrogen compound metabolic process GO:0006807 319 0.058
stem cell proliferation GO:0072089 4 0.057
cell migration involved in sprouting angiogenesis GO:0002042 8 0.056
determination of bilateral symmetry GO:0009855 204 0.056
blood vessel endothelial cell migration GO:0043534 18 0.056
cell migration GO:0016477 237 0.053
response to drug GO:0042493 3 0.052
response to monosaccharide GO:0034284 3 0.051
protein import into nucleus GO:0006606 3 0.050
response to glucose GO:0009749 3 0.050
embryonic hemopoiesis GO:0035162 53 0.049
localization of cell GO:0051674 244 0.049
hemopoiesis GO:0030097 183 0.049
epithelial tube morphogenesis GO:0060562 148 0.049
regulation of cell shape GO:0008360 1 0.049
regulation of nitrogen compound metabolic process GO:0051171 251 0.048
regulation of cellular metabolic process GO:0031323 320 0.047
embryo development ending in birth or egg hatching GO:0009792 271 0.047
heterocycle biosynthetic process GO:0018130 215 0.046
aging GO:0007568 2 0.046
signal transduction GO:0007165 455 0.045
regulation of rna metabolic process GO:0051252 224 0.044
blood circulation GO:0008015 87 0.043
locomotion GO:0040011 313 0.043
somite development GO:0061053 96 0.043
organic substance biosynthetic process GO:1901576 289 0.043
central nervous system development GO:0007417 387 0.042
regulation of intracellular protein transport GO:0033157 3 0.042
organelle localization GO:0051640 49 0.042
skeletal system development GO:0001501 181 0.042
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.041
digestive tract morphogenesis GO:0048546 231 0.041
cellular macromolecule metabolic process GO:0044260 391 0.041
regulation of angiogenesis GO:0045765 26 0.040
cell projection assembly GO:0030031 64 0.040
response to nutrient GO:0007584 3 0.040
glucose import GO:0046323 2 0.039
camera type eye morphogenesis GO:0048593 108 0.039
head development GO:0060322 303 0.039
maintenance of location GO:0051235 4 0.039
embryonic skeletal system development GO:0048706 97 0.038
enzyme linked receptor protein signaling pathway GO:0007167 106 0.037
negative regulation of protein transport GO:0051224 3 0.037
response to hexose GO:0009746 3 0.037
autophagy GO:0006914 4 0.037
mesoderm development GO:0007498 88 0.037
muscle cell migration GO:0014812 4 0.037
regulation of blood coagulation GO:0030193 1 0.037
microtubule based process GO:0007017 60 0.036
muscle structure development GO:0061061 196 0.036
regulation of biological quality GO:0065008 263 0.035
circulatory system process GO:0003013 87 0.034
inositol lipid mediated signaling GO:0048017 2 0.033
regulation of signaling GO:0023051 235 0.033
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.033
system process GO:0003008 185 0.033
connective tissue development GO:0061448 99 0.033
neural precursor cell proliferation GO:0061351 20 0.032
negative regulation of biological process GO:0048519 304 0.032
positive regulation of cellular component biogenesis GO:0044089 3 0.032
microtubule cytoskeleton organization GO:0000226 33 0.031
regulation of vasculature development GO:1901342 33 0.031
neural tube development GO:0021915 62 0.031
cellular component biogenesis GO:0044085 178 0.031
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.031
cell matrix adhesion GO:0007160 4 0.031
negative regulation of signal transduction GO:0009968 94 0.030
smooth muscle contraction GO:0006939 2 0.030
somitogenesis GO:0001756 87 0.030
negative regulation of map kinase activity GO:0043407 2 0.030
embryonic heart tube development GO:0035050 133 0.030
cartilage development GO:0051216 96 0.029
transcription dna templated GO:0006351 181 0.029
establishment of protein localization to organelle GO:0072594 4 0.029
negative regulation of synapse assembly GO:0051964 2 0.029
nucleic acid metabolic process GO:0090304 244 0.029
amine metabolic process GO:0009308 2 0.028
regulation of cytokine production GO:0001817 3 0.028
regulation of metabolic process GO:0019222 359 0.028
cytoskeleton organization GO:0007010 96 0.028
ear development GO:0043583 127 0.028
immune system development GO:0002520 191 0.027
epidermis development GO:0008544 48 0.027
cellular aromatic compound metabolic process GO:0006725 295 0.027
adherens junction organization GO:0034332 4 0.027
epithelial cell migration GO:0010631 25 0.027
organelle organization GO:0006996 227 0.027
regulation of developmental process GO:0050793 247 0.026
i kappab kinase nf kappab signaling GO:0007249 4 0.026
regulation of protein transport GO:0051223 3 0.026
protein localization to nucleus GO:0034504 3 0.026
protein import GO:0017038 3 0.026
apoptotic process GO:0006915 116 0.026
nucleocytoplasmic transport GO:0006913 4 0.026
negative regulation of protein kinase activity GO:0006469 4 0.026
positive regulation of multicellular organismal process GO:0051240 52 0.026
negative regulation of mapk cascade GO:0043409 4 0.025
heterocycle metabolic process GO:0046483 290 0.025
negative regulation of kinase activity GO:0033673 4 0.025
regulation of protein targeting GO:1903533 2 0.025
regulation of circadian rhythm GO:0042752 4 0.025
determination of left right symmetry GO:0007368 179 0.025
negative regulation of protein phosphorylation GO:0001933 4 0.025
regulation of primary metabolic process GO:0080090 311 0.024
organic cyclic compound metabolic process GO:1901360 301 0.024
phosphatidylinositol mediated signaling GO:0048015 2 0.024
myotome development GO:0061055 1 0.024
positive regulation of transport GO:0051050 2 0.024
regulation of cytoplasmic transport GO:1903649 4 0.024
aromatic compound biosynthetic process GO:0019438 217 0.024
positive regulation of rna metabolic process GO:0051254 59 0.024
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.023
phagocytosis GO:0006909 3 0.023
regulation of anatomical structure morphogenesis GO:0022603 130 0.023
epithelium migration GO:0090132 25 0.023
regulation of glucose import GO:0046324 1 0.023
positive regulation of cell cycle GO:0045787 3 0.023
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.023
regulation of cell communication GO:0010646 232 0.022
nuclear transport GO:0051169 4 0.022
rna 3 end processing GO:0031123 2 0.022
regionalization GO:0003002 274 0.022
cellular amino acid metabolic process GO:0006520 7 0.022
small molecule metabolic process GO:0044281 77 0.022
nuclear import GO:0051170 3 0.022
immune system process GO:0002376 241 0.022
ubiquitin dependent protein catabolic process GO:0006511 3 0.021
synaptic growth at neuromuscular junction GO:0051124 2 0.021
notochord development GO:0030903 54 0.021
response to abiotic stimulus GO:0009628 122 0.021
regulation of glucose transport GO:0010827 1 0.021
cellular nitrogen compound metabolic process GO:0034641 290 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.021
positive regulation of macromolecule metabolic process GO:0010604 93 0.021
convergent extension involved in gastrulation GO:0060027 71 0.021
positive regulation of catabolic process GO:0009896 4 0.021
regulation of neural precursor cell proliferation GO:2000177 3 0.021
organelle assembly GO:0070925 110 0.021
generation of neurons GO:0048699 385 0.021
regulation of macromolecule metabolic process GO:0060255 317 0.021
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.020
gastrulation GO:0007369 208 0.020
cellular component assembly involved in morphogenesis GO:0010927 107 0.020
peptide transport GO:0015833 1 0.020
single organism nuclear import GO:1902593 3 0.020
inner ear development GO:0048839 126 0.020
single organism localization GO:1902578 225 0.020
positive regulation of glucose import GO:0046326 1 0.020
negative regulation of protein localization to nucleus GO:1900181 2 0.020
regulation of cell motility GO:2000145 46 0.020
biosynthetic process GO:0009058 294 0.020
lipid catabolic process GO:0016042 4 0.019
regulation of cellular component movement GO:0051270 55 0.019
synaptic target recognition GO:0008039 1 0.019
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.019
regulation of establishment of protein localization GO:0070201 4 0.019
single organism organelle organization GO:1902589 199 0.019
regulation of macromolecule biosynthetic process GO:0010556 225 0.019
regulation of wound healing GO:0061041 2 0.019
regulation of rna biosynthetic process GO:2001141 213 0.019
striated muscle cell differentiation GO:0051146 129 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.019
regulation of epithelial cell proliferation GO:0050678 3 0.019
macromolecular complex subunit organization GO:0043933 74 0.019
segmentation GO:0035282 97 0.019
positive regulation of cell matrix adhesion GO:0001954 1 0.018
lipid storage GO:0019915 1 0.018
actomyosin structure organization GO:0031032 53 0.018
positive regulation of blood circulation GO:1903524 2 0.018
positive regulation of cytoskeleton organization GO:0051495 3 0.018
heart morphogenesis GO:0003007 156 0.018
rna biosynthetic process GO:0032774 181 0.018
cellular response to external stimulus GO:0071496 2 0.018
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.018
positive regulation of muscle cell differentiation GO:0051149 1 0.018
positive regulation of gliogenesis GO:0014015 2 0.018
forebrain development GO:0030900 96 0.018
leukocyte proliferation GO:0070661 1 0.017
intracellular signal transduction GO:0035556 85 0.017
modification dependent protein catabolic process GO:0019941 3 0.017
kidney development GO:0001822 92 0.017
skeletal system morphogenesis GO:0048705 102 0.017
embryonic viscerocranium morphogenesis GO:0048703 52 0.017
regulation of apoptotic process GO:0042981 98 0.017
regulation of cell substrate adhesion GO:0010810 1 0.017
multicellular organism growth GO:0035264 4 0.017
heart looping GO:0001947 94 0.017
determination of heart left right asymmetry GO:0061371 117 0.017
lens fiber cell morphogenesis GO:0070309 3 0.017
regulation of hemostasis GO:1900046 1 0.017
signal transduction in absence of ligand GO:0038034 1 0.017
cellular protein catabolic process GO:0044257 4 0.017
regulation of organ growth GO:0046620 3 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.017
mononuclear cell proliferation GO:0032943 1 0.017
negative regulation of response to stimulus GO:0048585 104 0.017
response to chemical GO:0042221 320 0.017
oxoacid metabolic process GO:0043436 31 0.016
protein secretion GO:0009306 1 0.016
cellular amine metabolic process GO:0044106 2 0.016
regeneration GO:0031099 91 0.016
regulation of cell matrix adhesion GO:0001952 1 0.016
cellular response to hormone stimulus GO:0032870 39 0.016
actin cytoskeleton organization GO:0030036 63 0.016
negative regulation of cytoplasmic transport GO:1903650 2 0.016
pancreas development GO:0031016 84 0.016
neurotransmitter transport GO:0006836 2 0.016
negative regulation of angiogenesis GO:0016525 7 0.016
developmental growth GO:0048589 166 0.016
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.016
growth GO:0040007 174 0.016
regulation of growth GO:0040008 42 0.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.016
establishment of organelle localization GO:0051656 45 0.016
macromolecule biosynthetic process GO:0009059 227 0.015
regulation of protein import into nucleus GO:0042306 2 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.015
regulation of response to stimulus GO:0048583 269 0.015
nucleic acid templated transcription GO:0097659 181 0.015
homeostatic process GO:0042592 142 0.015
positive regulation of striated muscle tissue development GO:0045844 1 0.015
negative chemotaxis GO:0050919 1 0.015
actin filament based process GO:0030029 64 0.015
gland development GO:0048732 143 0.015
response to stress GO:0006950 263 0.015
odontogenesis of dentin containing tooth GO:0042475 1 0.014
nuclear migration GO:0007097 3 0.014
regulation of filopodium assembly GO:0051489 2 0.014
anterior posterior pattern specification GO:0009952 152 0.014
g2 m transition of mitotic cell cycle GO:0000086 4 0.014
negative regulation of epithelial cell proliferation GO:0050680 1 0.014
negative regulation of cell communication GO:0010648 96 0.014
female gonad development GO:0008585 4 0.014
negative regulation of cellular process GO:0048523 283 0.014
developmental pigmentation GO:0048066 48 0.014
biological adhesion GO:0022610 40 0.014
negative regulation of protein complex assembly GO:0031333 1 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
antimicrobial humoral response GO:0019730 2 0.014
sensory perception of chemical stimulus GO:0007606 3 0.014
negative regulation of neural precursor cell proliferation GO:2000178 1 0.014
gene expression GO:0010467 252 0.014
hexose transport GO:0008645 6 0.014
membrane fusion GO:0061025 2 0.014
regulation of mrna processing GO:0050684 3 0.014
regulation of blood pressure GO:0008217 1 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
central nervous system neuron differentiation GO:0021953 74 0.013
hindbrain development GO:0030902 91 0.013
establishment of localization GO:0051234 244 0.013
glial cell proliferation GO:0014009 4 0.013
regulation of protein catabolic process GO:0042176 1 0.013
endocardium morphogenesis GO:0003160 4 0.013
lymph vessel development GO:0001945 27 0.013
regulation of transcription dna templated GO:0006355 213 0.013
regulation of mrna catabolic process GO:0061013 3 0.013
muscle cell development GO:0055001 115 0.013
lymphocyte proliferation GO:0046651 1 0.013
epidermal cell fate specification GO:0009957 4 0.013
cell cycle g2 m phase transition GO:0044839 4 0.013
regulation of multicellular organism growth GO:0040014 4 0.013
bmp signaling pathway GO:0030509 52 0.013
notch signaling pathway GO:0007219 35 0.013
regulation of cell activation GO:0050865 1 0.013
cellular nitrogen compound biosynthetic process GO:0044271 218 0.013
neuron differentiation GO:0030182 353 0.013
ovulation cycle GO:0042698 2 0.013
regulation of locomotion GO:0040012 55 0.013
myeloid cell differentiation GO:0030099 86 0.013
mitotic cell cycle GO:0000278 64 0.013
striated muscle cell development GO:0055002 108 0.013
regulation of epidermis development GO:0045682 2 0.013
organic cyclic compound biosynthetic process GO:1901362 223 0.013
regulation of synapse organization GO:0050807 3 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.013
cellular response to chemical stimulus GO:0070887 157 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.013
cell substrate adhesion GO:0031589 4 0.013
dorsal ventral pattern formation GO:0009953 125 0.012
negative regulation of intracellular transport GO:0032387 3 0.012
organic acid metabolic process GO:0006082 31 0.012
developmental programmed cell death GO:0010623 4 0.012
cell cycle GO:0007049 93 0.012
regulation of autophagy GO:0010506 3 0.012
positive regulation of epithelial cell differentiation GO:0030858 2 0.012
mesenchyme development GO:0060485 127 0.012
regulation of protein complex assembly GO:0043254 3 0.012
tissue migration GO:0090130 37 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
spinal cord development GO:0021510 46 0.012
neuromast development GO:0048884 46 0.012
wnt signaling pathway GO:0016055 80 0.012
cell death GO:0008219 121 0.012
regulation of reproductive process GO:2000241 4 0.012
protein modification process GO:0036211 100 0.012
cellular macromolecule biosynthetic process GO:0034645 224 0.012
patterning of blood vessels GO:0001569 15 0.012
vascular process in circulatory system GO:0003018 6 0.012
establishment of synaptic vesicle localization GO:0097480 1 0.012
regulation of cellular component organization GO:0051128 86 0.012
positive regulation of cellular biosynthetic process GO:0031328 68 0.012
synaptic transmission cholinergic GO:0007271 4 0.012
positive regulation of cell activation GO:0050867 1 0.012
response to hormone GO:0009725 48 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.012
ovulation cycle process GO:0022602 2 0.012
embryonic organ morphogenesis GO:0048562 274 0.011
regulation of cell migration GO:0030334 40 0.011
positive regulation of cytokine production GO:0001819 2 0.011
negative regulation of intracellular protein transport GO:0090317 3 0.011
regulation of synaptic plasticity GO:0048167 1 0.011
synaptic vesicle transport GO:0048489 1 0.011
regulation of neurotransmitter secretion GO:0046928 1 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
response to endogenous stimulus GO:0009719 83 0.011
regulation of synapse assembly GO:0051963 3 0.011
regulation of skeletal muscle tissue development GO:0048641 4 0.011
positive regulation of secretion GO:0051047 1 0.011
innervation GO:0060384 3 0.011
regulation of cell projection assembly GO:0060491 4 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.011
positive regulation of protein kinase b signaling GO:0051897 1 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
cytokinesis GO:0000910 3 0.011
response to organic substance GO:0010033 153 0.011
nucleobase containing compound metabolic process GO:0006139 274 0.011
heart process GO:0003015 71 0.011
ventricular cardiac muscle tissue development GO:0003229 3 0.011
epithelial cell differentiation GO:0030855 116 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
monoamine transport GO:0015844 1 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
cilium assembly GO:0042384 58 0.011
regulation of nucleic acid templated transcription GO:1903506 213 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
locomotor rhythm GO:0045475 3 0.011
positive regulation of biological process GO:0048518 253 0.011
regulation of multicellular organismal process GO:0051239 277 0.011
regulation of endothelial cell proliferation GO:0001936 1 0.010
cellular response to radiation GO:0071478 4 0.010
endothelial cell migration GO:0043542 19 0.010
neuron development GO:0048666 262 0.010
single organism membrane fusion GO:0044801 2 0.010
cellular biosynthetic process GO:0044249 286 0.010
chemosensory behavior GO:0007635 1 0.010
response to wounding GO:0009611 116 0.010
protein metabolic process GO:0019538 183 0.010
guanosine containing compound metabolic process GO:1901068 4 0.010
stem cell maintenance GO:0019827 4 0.010
chondrocyte development GO:0002063 4 0.010
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 1 0.010
positive regulation of biosynthetic process GO:0009891 68 0.010

pdgfrb2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.014
sensory system disease DOID:0050155 0 0.011