Danio rerio

5 known processes

pdhb

pyruvate dehydrogenase (lipoamide) beta

(Aliases: wu:fc76a05,zgc:64062)

pdhb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 2 0.603
Worm
atp synthesis coupled electron transport GO:0042773 1 0.593
respiratory electron transport chain GO:0022904 2 0.570
small molecule metabolic process GO:0044281 77 0.461
Human Yeast
electron transport chain GO:0022900 2 0.392
cellular respiration GO:0045333 3 0.374
Human
mitochondrial atp synthesis coupled electron transport GO:0042775 1 0.340
ion transport GO:0006811 114 0.320
phosphorus metabolic process GO:0006793 109 0.319
Human Yeast
oxidative phosphorylation GO:0006119 1 0.310
single organism metabolic process GO:0044710 217 0.309
purine containing compound biosynthetic process GO:0072522 20 0.271
larval development GO:0002164 2 0.269
organonitrogen compound metabolic process GO:1901564 74 0.215
ribonucleotide metabolic process GO:0009259 27 0.204
organophosphate biosynthetic process GO:0090407 23 0.195
nucleobase containing compound metabolic process GO:0006139 274 0.173
organic cyclic compound metabolic process GO:1901360 301 0.161
signal transduction GO:0007165 455 0.148
organic cyclic compound biosynthetic process GO:1901362 223 0.145
oxoacid metabolic process GO:0043436 31 0.126
Human Yeast
embryo development ending in birth or egg hatching GO:0009792 271 0.121
Worm
organic acid metabolic process GO:0006082 31 0.116
Human Yeast
cell part morphogenesis GO:0032990 246 0.116
nucleobase containing small molecule metabolic process GO:0055086 32 0.110
response to chemical GO:0042221 320 0.107
regulation of metabolic process GO:0019222 359 0.101
transmembrane transport GO:0055085 120 0.099
transport GO:0006810 220 0.092
carbohydrate derivative metabolic process GO:1901135 61 0.089
nitrogen compound metabolic process GO:0006807 319 0.085
response to stress GO:0006950 263 0.084
regulation of biological quality GO:0065008 263 0.081
organic substance biosynthetic process GO:1901576 289 0.080
Human Yeast
single organism localization GO:1902578 225 0.078
cellular nitrogen compound metabolic process GO:0034641 290 0.077
phosphate containing compound metabolic process GO:0006796 108 0.074
locomotion GO:0040011 313 0.072
carboxylic acid metabolic process GO:0019752 22 0.069
Human Yeast
organelle organization GO:0006996 227 0.068
cellular component morphogenesis GO:0032989 336 0.066
biosynthetic process GO:0009058 294 0.066
Human Yeast
purine containing compound metabolic process GO:0072521 29 0.065
female gamete generation GO:0007292 14 0.064
cellular nitrogen compound biosynthetic process GO:0044271 218 0.063
pigmentation GO:0043473 85 0.063
carbohydrate derivative biosynthetic process GO:1901137 43 0.063
nucleoside monophosphate catabolic process GO:0009125 4 0.062
pyruvate metabolic process GO:0006090 1 0.061
Human Yeast
single organism transport GO:0044765 206 0.058
ribonucleoside monophosphate catabolic process GO:0009158 4 0.058
heterocycle biosynthetic process GO:0018130 215 0.058
organophosphate metabolic process GO:0019637 37 0.057
macromolecular complex subunit organization GO:0043933 74 0.057
behavior GO:0007610 74 0.057
digestive system development GO:0055123 289 0.056
multicellular organism reproduction GO:0032504 35 0.054
nucleoside metabolic process GO:0009116 11 0.054
multicellular organism growth GO:0035264 4 0.053
heterocycle metabolic process GO:0046483 290 0.052
purine ribonucleotide metabolic process GO:0009150 27 0.052
spermatid differentiation GO:0048515 2 0.052
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.051
cellular aromatic compound metabolic process GO:0006725 295 0.049
multi organism process GO:0051704 134 0.049
multicellular organismal reproductive process GO:0048609 35 0.049
atp catabolic process GO:0006200 4 0.049
mitochondrion organization GO:0007005 4 0.048
gamete generation GO:0007276 33 0.048
maintenance of location GO:0051235 4 0.048
cellular biosynthetic process GO:0044249 286 0.047
Human Yeast
cellular amino acid metabolic process GO:0006520 7 0.047
nucleotide metabolic process GO:0009117 28 0.045
apoptotic process GO:0006915 116 0.045
germ cell development GO:0007281 22 0.045
purine nucleoside monophosphate catabolic process GO:0009128 4 0.044
cation transport GO:0006812 81 0.044
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.043
establishment of localization GO:0051234 244 0.043
response to external stimulus GO:0009605 264 0.043
digestive tract development GO:0048565 265 0.042
system process GO:0003008 185 0.042
reproductive process GO:0022414 40 0.042
regulation of multicellular organism growth GO:0040014 4 0.041
phagocytosis GO:0006909 3 0.041
ribonucleotide biosynthetic process GO:0009260 20 0.041
response to drug GO:0042493 3 0.041
stem cell proliferation GO:0072089 4 0.040
ribose phosphate metabolic process GO:0019693 27 0.039
spermatid development GO:0007286 2 0.038
cellular component assembly GO:0022607 170 0.038
tube morphogenesis GO:0035239 349 0.038
amine metabolic process GO:0009308 2 0.038
cellular protein complex assembly GO:0043623 19 0.037
cell surface receptor signaling pathway GO:0007166 325 0.037
liver development GO:0001889 96 0.036
sexual reproduction GO:0019953 36 0.036
organic acid catabolic process GO:0016054 3 0.034
ion transmembrane transport GO:0034220 91 0.034
nucleoside phosphate metabolic process GO:0006753 28 0.033
cellular amine metabolic process GO:0044106 2 0.033
inorganic cation transmembrane transport GO:0098662 50 0.033
programmed cell death GO:0012501 119 0.033
cellular component movement GO:0006928 335 0.032
organonitrogen compound biosynthetic process GO:1901566 47 0.031
cortical cytoskeleton organization GO:0030865 1 0.031
purine nucleotide metabolic process GO:0006163 27 0.030
carboxylic acid catabolic process GO:0046395 3 0.030
cellular response to chemical stimulus GO:0070887 157 0.029
negative regulation of biological process GO:0048519 304 0.029
regulation of developmental process GO:0050793 247 0.029
dicarboxylic acid metabolic process GO:0043648 1 0.028
cell motility GO:0048870 244 0.027
brain development GO:0007420 293 0.027
mitochondrial transport GO:0006839 2 0.027
organic substance catabolic process GO:1901575 28 0.027
oogenesis GO:0048477 14 0.027
regulation of protein localization to nucleus GO:1900180 2 0.026
generation of neurons GO:0048699 385 0.026
regulation of protein complex assembly GO:0043254 3 0.026
cell death GO:0008219 121 0.026
regulation of cellular ketone metabolic process GO:0010565 7 0.026
anion transport GO:0006820 38 0.025
negative regulation of epithelial cell proliferation GO:0050680 1 0.025
single organism nuclear import GO:1902593 3 0.025
localization of cell GO:0051674 244 0.025
regulation of primary metabolic process GO:0080090 311 0.025
growth GO:0040007 174 0.025
muscle cell development GO:0055001 115 0.024
phosphorylation GO:0016310 69 0.024
cellular component disassembly GO:0022411 1 0.024
regulation of establishment of protein localization GO:0070201 4 0.024
developmental process involved in reproduction GO:0003006 27 0.024
gastrulation GO:0007369 208 0.024
nuclear transport GO:0051169 4 0.024
protein complex subunit organization GO:0071822 46 0.023
single organism organelle organization GO:1902589 199 0.023
muscle structure development GO:0061061 196 0.023
negative regulation of catabolic process GO:0009895 3 0.023
metal ion transport GO:0030001 58 0.023
regulation of dna replication GO:0006275 3 0.022
eye development GO:0001654 277 0.022
lipid storage GO:0019915 1 0.022
small molecule catabolic process GO:0044282 3 0.022
digestive tract morphogenesis GO:0048546 231 0.022
regulation of cellular biosynthetic process GO:0031326 245 0.021
regulation of signal transduction GO:0009966 225 0.021
regulation of intracellular protein transport GO:0033157 3 0.021
sensory organ development GO:0007423 393 0.020
nucleic acid metabolic process GO:0090304 244 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
generation of precursor metabolites and energy GO:0006091 5 0.020
Human
branched chain amino acid metabolic process GO:0009081 1 0.020
cytoskeleton organization GO:0007010 96 0.020
cellular macromolecule metabolic process GO:0044260 391 0.020
cognition GO:0050890 1 0.020
camera type eye development GO:0043010 222 0.020
mitochondrial electron transport nadh to ubiquinone GO:0006120 1 0.019
cellular protein catabolic process GO:0044257 4 0.019
protein import into nucleus GO:0006606 3 0.019
regulation of cell shape GO:0008360 1 0.019
nucleocytoplasmic transport GO:0006913 4 0.019
nucleobase containing compound biosynthetic process GO:0034654 205 0.019
negative regulation of cellular catabolic process GO:0031330 3 0.019
macromolecular complex disassembly GO:0032984 1 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
negative regulation of kinase activity GO:0033673 4 0.018
regulation of multicellular organismal process GO:0051239 277 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.018
neuron differentiation GO:0030182 353 0.018
proteasomal protein catabolic process GO:0010498 2 0.018
protein metabolic process GO:0019538 183 0.017
sequestering of calcium ion GO:0051208 3 0.017
response to organic substance GO:0010033 153 0.017
protein localization to nucleus GO:0034504 3 0.017
establishment of protein localization to organelle GO:0072594 4 0.017
intracellular transport GO:0046907 32 0.017
single organism biosynthetic process GO:0044711 71 0.017
Human Yeast
phagocytosis engulfment GO:0006911 1 0.017
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.017
gland development GO:0048732 143 0.017
cellular ketone metabolic process GO:0042180 11 0.017
regulation of epithelial cell proliferation GO:0050678 3 0.017
cellular carbohydrate metabolic process GO:0044262 4 0.017
mitochondrion morphogenesis GO:0070584 2 0.016
nucleoside monophosphate metabolic process GO:0009123 6 0.016
homeostatic process GO:0042592 142 0.016
regulation of signaling GO:0023051 235 0.016
reproduction GO:0000003 40 0.016
cell growth GO:0016049 57 0.016
regulation of cell death GO:0010941 103 0.016
regulation of cell communication GO:0010646 232 0.016
cellular macromolecular complex assembly GO:0034622 24 0.016
reactive oxygen species metabolic process GO:0072593 6 0.016
ribose phosphate biosynthetic process GO:0046390 20 0.016
response to wounding GO:0009611 116 0.016
regulation of biosynthetic process GO:0009889 250 0.015
death GO:0016265 121 0.015
negative regulation of metabolic process GO:0009892 86 0.015
regulation of binding GO:0051098 3 0.015
energy derivation by oxidation of organic compounds GO:0015980 5 0.015
Human
neurotransmitter transport GO:0006836 2 0.015
protein targeting to nucleus GO:0044744 3 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 5 0.014
response to abiotic stimulus GO:0009628 122 0.014
nuclear import GO:0051170 3 0.014
aromatic compound biosynthetic process GO:0019438 217 0.014
positive regulation of biological process GO:0048518 253 0.014
regulation of autophagy GO:0010506 3 0.014
protein complex biogenesis GO:0070271 30 0.014
regulation of macromolecule metabolic process GO:0060255 317 0.014
carbohydrate biosynthetic process GO:0016051 1 0.014
nuclear export GO:0051168 1 0.014
hemopoiesis GO:0030097 183 0.014
regulation of molecular function GO:0065009 70 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.014
renal system development GO:0072001 94 0.014
rna biosynthetic process GO:0032774 181 0.014
macromolecular complex assembly GO:0065003 35 0.014
regulation of rna metabolic process GO:0051252 224 0.013
head development GO:0060322 303 0.013
regulation of protein transport GO:0051223 3 0.013
sensory organ morphogenesis GO:0090596 200 0.013
inorganic ion transmembrane transport GO:0098660 57 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
protein import GO:0017038 3 0.013
actin cytoskeleton organization GO:0030036 63 0.013
ribonucleoside monophosphate metabolic process GO:0009161 5 0.013
regulation of programmed cell death GO:0043067 101 0.013
developmental growth GO:0048589 166 0.013
modification dependent macromolecule catabolic process GO:0043632 3 0.013
oxidation reduction process GO:0055114 41 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
neuroblast proliferation GO:0007405 2 0.012
positive regulation of transport GO:0051050 2 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.012
positive regulation of multicellular organismal process GO:0051240 52 0.012
protein complex assembly GO:0006461 30 0.012
cell morphogenesis GO:0000902 289 0.012
proteolysis GO:0006508 38 0.012
cellular macromolecule biosynthetic process GO:0034645 224 0.012
protein complex disassembly GO:0043241 1 0.012
striated muscle cell development GO:0055002 108 0.012
positive regulation of cellular component biogenesis GO:0044089 3 0.012
regulation of protein depolymerization GO:1901879 1 0.012
negative regulation of response to stimulus GO:0048585 104 0.012
neuron projection development GO:0031175 180 0.011
nucleoside biosynthetic process GO:0009163 2 0.011
intracellular signal transduction GO:0035556 85 0.011
adult behavior GO:0030534 2 0.011
protein depolymerization GO:0051261 1 0.011
establishment of localization in cell GO:0051649 77 0.011
single organism intracellular transport GO:1902582 25 0.011
positive regulation of metabolic process GO:0009893 108 0.011
rna localization GO:0006403 4 0.011
myofibril assembly GO:0030239 48 0.011
purine nucleoside triphosphate biosynthetic process GO:0009145 2 0.011
neuromuscular synaptic transmission GO:0007274 2 0.011
tissue remodeling GO:0048771 4 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
ribonucleoside metabolic process GO:0009119 11 0.011
cellular transition metal ion homeostasis GO:0046916 3 0.011
neuron projection guidance GO:0097485 86 0.011
regulation of gene expression GO:0010468 265 0.011
anion transmembrane transport GO:0098656 12 0.011
actin polymerization or depolymerization GO:0008154 2 0.011
protein polymerization GO:0051258 4 0.011
retina layer formation GO:0010842 24 0.011
cellular localization GO:0051641 97 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
cellular response to oxygen levels GO:0071453 1 0.011
atp metabolic process GO:0046034 5 0.011
multi organism reproductive process GO:0044703 36 0.011
response to external biotic stimulus GO:0043207 97 0.011
nucleotide biosynthetic process GO:0009165 21 0.011
regulation of cytokine production GO:0001817 3 0.011
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
negative regulation of cellular process GO:0048523 283 0.011
primary neural tube formation GO:0014020 1 0.010
cellular homeostasis GO:0019725 26 0.010
neurotransmitter secretion GO:0007269 2 0.010
coenzyme biosynthetic process GO:0009108 2 0.010
Human Yeast
regulation of leukocyte mediated immunity GO:0002703 1 0.010
regulation of blood vessel size GO:0050880 2 0.010
regulation of protein complex disassembly GO:0043244 1 0.010
glycosyl compound metabolic process GO:1901657 11 0.010
transcription dna templated GO:0006351 181 0.010
morphogenesis of an epithelium GO:0002009 333 0.010
heart development GO:0007507 313 0.010
nitric oxide metabolic process GO:0046209 2 0.010
cell migration GO:0016477 237 0.010
cell projection organization GO:0030030 284 0.010
neural retina development GO:0003407 49 0.010
positive regulation of cell adhesion GO:0045785 1 0.010
regulation of dendrite morphogenesis GO:0048814 3 0.010
negative regulation of cell communication GO:0010648 96 0.010

pdhb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.065
disease of anatomical entity DOID:7 0 0.030
disease of cellular proliferation DOID:14566 0 0.018
inherited metabolic disorder DOID:655 0 0.018
endocrine gland cancer DOID:170 0 0.017
cancer DOID:162 0 0.017
organ system cancer DOID:0050686 0 0.017