Danio rerio

0 known processes

pdia3

protein disulfide isomerase family A, member 3

(Aliases: Grp58,sb:cb825)

pdia3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to topologically incorrect protein GO:0035967 2 0.843
endoplasmic reticulum unfolded protein response GO:0030968 2 0.620
er nucleus signaling pathway GO:0006984 2 0.506
cellular response to unfolded protein GO:0034620 2 0.474
larval development GO:0002164 2 0.355
cell substrate junction assembly GO:0007044 2 0.326
response to chemical GO:0042221 320 0.325
response to topologically incorrect protein GO:0035966 2 0.316
response to unfolded protein GO:0006986 2 0.248
golgi vesicle transport GO:0048193 3 0.207
cellular protein metabolic process GO:0044267 129 0.181
Worm
aging GO:0007568 2 0.169
maintenance of location GO:0051235 4 0.127
cellular response to organic substance GO:0071310 105 0.124
response to stress GO:0006950 263 0.122
glycosylation GO:0070085 11 0.121
lipid storage GO:0019915 1 0.095
cell junction organization GO:0034330 11 0.094
response to temperature stimulus GO:0009266 15 0.084
cellular macromolecule metabolic process GO:0044260 391 0.080
Worm
multicellular organism growth GO:0035264 4 0.071
Worm
signal transduction GO:0007165 455 0.066
Mouse
locomotion GO:0040011 313 0.062
response to organic substance GO:0010033 153 0.060
protein glycosylation GO:0006486 9 0.058
midbrain development GO:0030901 28 0.057
regulation of multicellular organism growth GO:0040014 4 0.054
Worm
multicellular organismal reproductive process GO:0048609 35 0.052
Worm
meiotic nuclear division GO:0007126 4 0.050
cellular component assembly GO:0022607 170 0.050
cellular response to chemical stimulus GO:0070887 157 0.048
response to abiotic stimulus GO:0009628 122 0.045
regulation of protein ubiquitination GO:0031396 3 0.045
response to endoplasmic reticulum stress GO:0034976 6 0.044
sensory perception of chemical stimulus GO:0007606 3 0.044
proteasomal protein catabolic process GO:0010498 2 0.043
response to heat GO:0009408 6 0.042
protein metabolic process GO:0019538 183 0.042
Worm
cell death GO:0008219 121 0.041
Mouse
positive regulation of biological process GO:0048518 253 0.041
Mouse Worm
toxin transport GO:1901998 2 0.037
single organism localization GO:1902578 225 0.037
regulation of gtpase activity GO:0043087 2 0.037
amine metabolic process GO:0009308 2 0.037
cellular response to stress GO:0033554 62 0.036
positive regulation of cellular component biogenesis GO:0044089 3 0.036
regulation of metabolic process GO:0019222 359 0.034
response to wounding GO:0009611 116 0.034
cellular component biogenesis GO:0044085 178 0.033
localization within membrane GO:0051668 1 0.032
cognition GO:0050890 1 0.032
multi organism process GO:0051704 134 0.031
Worm
cellular protein catabolic process GO:0044257 4 0.031
macromolecule modification GO:0043412 111 0.031
Worm
cell migration GO:0016477 237 0.029
rna localization GO:0006403 4 0.029
inner ear development GO:0048839 126 0.028
sexual reproduction GO:0019953 36 0.027
response to biotic stimulus GO:0009607 97 0.026
death GO:0016265 121 0.026
Mouse
regulation of nucleotide catabolic process GO:0030811 2 0.026
cell cycle g2 m phase transition GO:0044839 4 0.025
positive regulation of multi organism process GO:0043902 3 0.025
vacuolar transport GO:0007034 2 0.025
response to oxygen containing compound GO:1901700 55 0.024
response to ethanol GO:0045471 6 0.024
establishment of protein localization to organelle GO:0072594 4 0.024
gamete generation GO:0007276 33 0.024
response to other organism GO:0051707 97 0.023
regulation of metal ion transport GO:0010959 4 0.023
neurological system process GO:0050877 62 0.022
regulation of neurotransmitter secretion GO:0046928 1 0.022
spermatid development GO:0007286 2 0.022
hemidesmosome assembly GO:0031581 1 0.022
regulation of nucleoside metabolic process GO:0009118 2 0.022
cytokinesis GO:0000910 3 0.021
hydrogen peroxide metabolic process GO:0042743 2 0.021
growth GO:0040007 174 0.021
Worm
macromolecule glycosylation GO:0043413 9 0.021
developmental growth GO:0048589 166 0.021
Worm
regulation of purine nucleotide catabolic process GO:0033121 2 0.021
negative regulation of stem cell differentiation GO:2000737 2 0.021
negative regulation of protein phosphorylation GO:0001933 4 0.020
regulation of protein localization to nucleus GO:1900180 2 0.020
chemotaxis GO:0006935 104 0.020
programmed cell death GO:0012501 119 0.020
Mouse
protein n linked glycosylation GO:0006487 1 0.019
cytosolic calcium ion transport GO:0060401 3 0.019
regulation of cell activation GO:0050865 1 0.019
mononuclear cell proliferation GO:0032943 1 0.019
ear development GO:0043583 127 0.019
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.019
extrinsic apoptotic signaling pathway GO:0097191 3 0.019
Mouse
system process GO:0003008 185 0.019
modification dependent macromolecule catabolic process GO:0043632 3 0.019
axonogenesis GO:0007409 152 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.018
regulation of neurotransmitter transport GO:0051588 1 0.018
endodermal digestive tract morphogenesis GO:0061031 2 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
reproductive process GO:0022414 40 0.018
Worm
specification of symmetry GO:0009799 204 0.018
cellular nitrogen compound biosynthetic process GO:0044271 218 0.018
regulation of calcium ion transport GO:0051924 2 0.017
regulation of developmental process GO:0050793 247 0.017
Worm
cellular component movement GO:0006928 335 0.017
modification dependent protein catabolic process GO:0019941 3 0.017
regulation of blood vessel size GO:0050880 2 0.017
response to external stimulus GO:0009605 264 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.017
regulation of binding GO:0051098 3 0.017
cell maturation GO:0048469 23 0.016
iron ion transmembrane transport GO:0034755 3 0.016
negative regulation of reproductive process GO:2000242 3 0.016
cellular amine metabolic process GO:0044106 2 0.016
positive regulation of transport GO:0051050 2 0.016
lipid homeostasis GO:0055088 3 0.016
glial cell migration GO:0008347 3 0.016
negative regulation of cellular process GO:0048523 283 0.016
cell surface receptor signaling pathway GO:0007166 325 0.015
Mouse
reactive oxygen species metabolic process GO:0072593 6 0.015
apoptotic process GO:0006915 116 0.015
Mouse
regulation of axonogenesis GO:0050770 32 0.015
regulation of response to biotic stimulus GO:0002831 2 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
response to hydrogen peroxide GO:0042542 3 0.015
oocyte differentiation GO:0009994 14 0.015
regulation of growth GO:0040008 42 0.015
Worm
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
multicellular organism reproduction GO:0032504 35 0.014
Worm
single fertilization GO:0007338 3 0.014
regulation of transmembrane transporter activity GO:0022898 2 0.014
ubiquitin dependent protein catabolic process GO:0006511 3 0.014
cellular protein modification process GO:0006464 100 0.014
Worm
spermatid differentiation GO:0048515 2 0.014
homeostatic process GO:0042592 142 0.014
cell morphogenesis GO:0000902 289 0.014
Worm
positive regulation of epithelial cell differentiation GO:0030858 2 0.014
positive regulation of secretion by cell GO:1903532 1 0.014
positive regulation of cellular catabolic process GO:0031331 3 0.014
cellular response to organic cyclic compound GO:0071407 38 0.014
negative regulation of rna splicing GO:0033119 1 0.014
neurotransmitter transport GO:0006836 2 0.014
response to external biotic stimulus GO:0043207 97 0.014
myofibril assembly GO:0030239 48 0.013
lymphocyte proliferation GO:0046651 1 0.013
cellular response to biotic stimulus GO:0071216 3 0.013
digestive system development GO:0055123 289 0.013
intracellular mrna localization GO:0008298 1 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
lateral inhibition GO:0046331 1 0.013
actin cytoskeleton organization GO:0030036 63 0.013
stem cell maintenance GO:0019827 4 0.013
endothelial cell differentiation GO:0045446 20 0.013
chemosensory behavior GO:0007635 1 0.013
positive regulation of muscle cell differentiation GO:0051149 1 0.013
transport GO:0006810 220 0.013
oocyte development GO:0048599 14 0.013
single organism reproductive process GO:0044702 40 0.013
Worm
positive regulation of dna templated transcription elongation GO:0032786 1 0.013
regulation of striated muscle contraction GO:0006942 2 0.013
embryonic organ development GO:0048568 381 0.013
regulation of stem cell differentiation GO:2000736 4 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
er to golgi vesicle mediated transport GO:0006888 1 0.012
regulation of response to stimulus GO:0048583 269 0.012
Mouse
regulation of histone methylation GO:0031060 3 0.012
regulation of cell growth GO:0001558 29 0.012
oocyte maturation GO:0001556 4 0.012
muscle cell differentiation GO:0042692 139 0.012
reproduction GO:0000003 40 0.012
Worm
regulation of chromosome segregation GO:0051983 1 0.012
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.012
response to antibiotic GO:0046677 1 0.012
regulation of protein transport GO:0051223 3 0.012
regulation of cellular ketone metabolic process GO:0010565 7 0.012
cell aging GO:0007569 2 0.012
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.011
positive regulation of immune effector process GO:0002699 3 0.011
regulation of sodium ion transport GO:0002028 2 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
nucleotide biosynthetic process GO:0009165 21 0.011
regulation of cytokine mediated signaling pathway GO:0001959 3 0.011
leukocyte proliferation GO:0070661 1 0.011
defense response to fungus GO:0050832 2 0.011
transmembrane transport GO:0055085 120 0.011
muscle structure development GO:0061061 196 0.011
negative regulation of multi organism process GO:0043901 3 0.011
regulation of autophagy GO:0010506 3 0.011
oogenesis GO:0048477 14 0.011
response to estrogen GO:0043627 27 0.010
establishment of localization GO:0051234 244 0.010
regulation of cellular ph GO:0030641 1 0.010
protein import into nucleus GO:0006606 3 0.010
neuron projection morphogenesis GO:0048812 161 0.010
regulation of protein metabolic process GO:0051246 56 0.010
cytoskeleton organization GO:0007010 96 0.010
cell junction assembly GO:0034329 7 0.010
regulation of reproductive process GO:2000241 4 0.010
response to metal ion GO:0010038 34 0.010
regulation of localization GO:0032879 104 0.010
germ cell development GO:0007281 22 0.010
positive regulation of epithelial cell migration GO:0010634 2 0.010
pronuclear migration GO:0035046 1 0.010

pdia3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.116
muscular disease DOID:0080000 0 0.023
myopathy DOID:423 0 0.023
musculoskeletal system disease DOID:17 0 0.023
muscle tissue disease DOID:66 0 0.023
nervous system disease DOID:863 0 0.019
connective tissue disease DOID:65 0 0.013
bone disease DOID:0080001 0 0.010
bone development disease DOID:0080006 0 0.010