Danio rerio

0 known processes

pds5a

PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)

(Aliases: MGC153878,zgc:66331,Aprin,zgc:153878,MGC66331)

pds5a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 2 0.225
larval development GO:0002164 2 0.223
cellular macromolecule metabolic process GO:0044260 391 0.129
Human
nitrogen compound metabolic process GO:0006807 319 0.115
Human
regulation of metabolic process GO:0019222 359 0.105
Human
macromolecule biosynthetic process GO:0009059 227 0.104
Human
gene expression GO:0010467 252 0.104
negative regulation of biological process GO:0048519 304 0.093
Human
regulation of gene expression GO:0010468 265 0.091
organic cyclic compound metabolic process GO:1901360 301 0.090
Human
histone h3 k4 methylation GO:0051568 2 0.090
cellular nitrogen compound metabolic process GO:0034641 290 0.089
Human
regulation of protein complex assembly GO:0043254 3 0.082
localization of cell GO:0051674 244 0.077
cellular component biogenesis GO:0044085 178 0.076
regulation of cell shape GO:0008360 1 0.075
nucleic acid metabolic process GO:0090304 244 0.071
Human
regulation of cellular metabolic process GO:0031323 320 0.070
Human
cellular aromatic compound metabolic process GO:0006725 295 0.070
Human
regulation of chromosome segregation GO:0051983 1 0.064
protein acetylation GO:0006473 2 0.063
single organism metabolic process GO:0044710 217 0.061
positive regulation of cell cycle GO:0045787 3 0.061
nucleobase containing compound metabolic process GO:0006139 274 0.058
Human
cellular component movement GO:0006928 335 0.057
cellular component assembly GO:0022607 170 0.056
heterocycle metabolic process GO:0046483 290 0.052
Human
protein metabolic process GO:0019538 183 0.052
single organism organelle organization GO:1902589 199 0.052
Human Worm
nuclear transport GO:0051169 4 0.051
locomotion GO:0040011 313 0.050
Worm
organelle organization GO:0006996 227 0.048
Human Worm
regulation of organelle organization GO:0033043 29 0.047
protein polyubiquitination GO:0000209 4 0.046
negative regulation of cellular process GO:0048523 283 0.046
Human
regulation of macromolecule metabolic process GO:0060255 317 0.044
Human
regulation of rna metabolic process GO:0051252 224 0.043
organic cyclic compound biosynthetic process GO:1901362 223 0.043
rna metabolic process GO:0016070 219 0.042
nucleocytoplasmic transport GO:0006913 4 0.042
cell migration GO:0016477 237 0.042
internal protein amino acid acetylation GO:0006475 2 0.041
protein acylation GO:0043543 3 0.041
protein import into nucleus GO:0006606 3 0.041
cellular ketone metabolic process GO:0042180 11 0.040
response to stress GO:0006950 263 0.039
embryo development ending in birth or egg hatching GO:0009792 271 0.039
Worm
macromolecule modification GO:0043412 111 0.039
positive regulation of cellular biosynthetic process GO:0031328 68 0.037
translational initiation GO:0006413 3 0.036
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.036
Human
internal peptidyl lysine acetylation GO:0018393 2 0.035
positive regulation of cellular metabolic process GO:0031325 94 0.035
regulation of anatomical structure morphogenesis GO:0022603 130 0.035
cellular component morphogenesis GO:0032989 336 0.033
maintenance of location GO:0051235 4 0.033
regulation of circadian rhythm GO:0042752 4 0.033
positive regulation of cellular component biogenesis GO:0044089 3 0.032
cellular protein metabolic process GO:0044267 129 0.032
regulation of protein catabolic process GO:0042176 1 0.032
cytoskeleton organization GO:0007010 96 0.031
rna localization GO:0006403 4 0.031
digestive system development GO:0055123 289 0.031
regulation of cellular component organization GO:0051128 86 0.031
regulation of primary metabolic process GO:0080090 311 0.031
Human
cell motility GO:0048870 244 0.031
nucleobase containing compound biosynthetic process GO:0034654 205 0.030
regulation of cellular biosynthetic process GO:0031326 245 0.030
Human
establishment of protein localization to organelle GO:0072594 4 0.030
response to chemical GO:0042221 320 0.030
regulation of biological quality GO:0065008 263 0.030
phagocytosis GO:0006909 3 0.029
nuclear import GO:0051170 3 0.028
modification dependent macromolecule catabolic process GO:0043632 3 0.028
skeletal system development GO:0001501 181 0.028
protein modification process GO:0036211 100 0.028
organic substance biosynthetic process GO:1901576 289 0.028
Human
positive regulation of chromatin modification GO:1903310 1 0.027
rna biosynthetic process GO:0032774 181 0.027
mitotic cell cycle process GO:1903047 48 0.027
Human Worm
positive regulation of transcription dna templated GO:0045893 57 0.027
digestive tract development GO:0048565 265 0.027
cellular macromolecule biosynthetic process GO:0034645 224 0.027
Human
positive regulation of gene expression GO:0010628 71 0.027
positive regulation of nucleic acid templated transcription GO:1903508 57 0.027
protein import GO:0017038 3 0.026
cellular protein modification process GO:0006464 100 0.026
cell projection organization GO:0030030 284 0.026
regulation of response to stimulus GO:0048583 269 0.026
cell morphogenesis GO:0000902 289 0.026
stem cell division GO:0017145 1 0.025
organonitrogen compound metabolic process GO:1901564 74 0.025
g2 dna damage checkpoint GO:0031572 3 0.025
alternative mrna splicing via spliceosome GO:0000380 1 0.025
negative regulation of cell communication GO:0010648 96 0.025
response to drug GO:0042493 3 0.025
protein stabilization GO:0050821 2 0.025
regulation of developmental process GO:0050793 247 0.024
Worm
production of molecular mediator of immune response GO:0002440 2 0.024
macromolecular complex subunit organization GO:0043933 74 0.024
regulation of cell activation GO:0050865 1 0.024
transcription dna templated GO:0006351 181 0.024
fertilization GO:0009566 3 0.023
regulation of multicellular organismal process GO:0051239 277 0.023
Worm
single organism nuclear import GO:1902593 3 0.023
regulation of nitrogen compound metabolic process GO:0051171 251 0.023
Human
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.023
positive regulation of cell activation GO:0050867 1 0.023
protein targeting to nucleus GO:0044744 3 0.022
positive regulation of cellular process GO:0048522 201 0.022
aromatic compound biosynthetic process GO:0019438 217 0.022
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.022
single organism localization GO:1902578 225 0.022
regulation of biosynthetic process GO:0009889 250 0.022
Human
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.022
blood vessel development GO:0001568 246 0.021
carboxylic acid metabolic process GO:0019752 22 0.021
amine metabolic process GO:0009308 2 0.021
small gtpase mediated signal transduction GO:0007264 8 0.021
signal transduction GO:0007165 455 0.021
protein localization to nucleus GO:0034504 3 0.021
regulation of cellular amine metabolic process GO:0033238 0 0.021
cell substrate junction assembly GO:0007044 2 0.021
regulation of cell cycle GO:0051726 52 0.021
multicellular organism growth GO:0035264 4 0.021
Worm
cell substrate adhesion GO:0031589 4 0.021
immune system development GO:0002520 191 0.020
cellular biosynthetic process GO:0044249 286 0.020
Human
embryonic organ development GO:0048568 381 0.020
fin regeneration GO:0031101 51 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.019
tube morphogenesis GO:0035239 349 0.019
determination of bilateral symmetry GO:0009855 204 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
organic acid metabolic process GO:0006082 31 0.019
regeneration GO:0031099 91 0.019
regulation of macromolecule biosynthetic process GO:0010556 225 0.019
Human
negative regulation of protein phosphorylation GO:0001933 4 0.019
regulation of rna biosynthetic process GO:2001141 213 0.019
cellular response to stress GO:0033554 62 0.019
mitotic g2 m transition checkpoint GO:0044818 3 0.019
multi organism cellular process GO:0044764 2 0.018
oxoacid metabolic process GO:0043436 31 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
peptidyl lysine acetylation GO:0018394 2 0.018
nuclear export GO:0051168 1 0.018
cellular amine metabolic process GO:0044106 2 0.018
response to external stimulus GO:0009605 264 0.018
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.018
regulation of protein transport GO:0051223 3 0.018
regulation of transcription dna templated GO:0006355 213 0.018
positive regulation of dna metabolic process GO:0051054 1 0.018
positive regulation of biological process GO:0048518 253 0.018
Worm
immune system process GO:0002376 241 0.018
regulation of nucleocytoplasmic transport GO:0046822 2 0.017
regulation of cytoplasmic transport GO:1903649 4 0.017
regulation of stem cell differentiation GO:2000736 4 0.017
positive regulation of immune effector process GO:0002699 3 0.017
histone lysine methylation GO:0034968 12 0.017
regulation of cell cycle process GO:0010564 20 0.017
heart morphogenesis GO:0003007 156 0.017
developmental growth GO:0048589 166 0.017
Worm
mitotic cell cycle GO:0000278 64 0.017
Human Worm
stem cell maintenance GO:0019827 4 0.017
regulation of production of molecular mediator of immune response GO:0002700 1 0.017
cellular component disassembly GO:0022411 1 0.017
regulation of mrna processing GO:0050684 3 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
establishment of localization GO:0051234 244 0.017
Worm
multi organism process GO:0051704 134 0.016
negative regulation of catabolic process GO:0009895 3 0.016
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.016
positive regulation of cytoskeleton organization GO:0051495 3 0.016
lipid storage GO:0019915 1 0.016
regulation of establishment of protein localization GO:0070201 4 0.016
chromosome organization GO:0051276 31 0.016
Human Worm
response to wounding GO:0009611 116 0.016
negative regulation of dna metabolic process GO:0051053 4 0.016
Human
positive regulation of macromolecule metabolic process GO:0010604 93 0.016
positive regulation of transport GO:0051050 2 0.016
response to abiotic stimulus GO:0009628 122 0.015
cell adhesion GO:0007155 40 0.015
blood vessel morphogenesis GO:0048514 216 0.015
muscle structure development GO:0061061 196 0.015
neuroblast proliferation GO:0007405 2 0.015
g2 m transition of mitotic cell cycle GO:0000086 4 0.015
regulation of meiotic cell cycle GO:0051445 1 0.015
regulation of stem cell proliferation GO:0072091 2 0.015
regulation of cytokine production GO:0001817 3 0.015
rna processing GO:0006396 25 0.015
regulation of cellular protein catabolic process GO:1903362 1 0.015
regulation of cellular protein metabolic process GO:0032268 52 0.014
rna export from nucleus GO:0006405 1 0.014
regulation of translational initiation GO:0006446 1 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
vasculature development GO:0001944 278 0.014
nucleic acid templated transcription GO:0097659 181 0.014
central nervous system development GO:0007417 387 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.014
regulation of binding GO:0051098 3 0.014
spermatid differentiation GO:0048515 2 0.014
positive regulation of chromosome organization GO:2001252 1 0.014
cell cycle g2 m phase transition GO:0044839 4 0.014
ubiquitin dependent protein catabolic process GO:0006511 3 0.014
negative regulation of macromolecule metabolic process GO:0010605 76 0.014
Human
nuclear migration GO:0007097 3 0.014
single fertilization GO:0007338 3 0.014
cellular response to chemical stimulus GO:0070887 157 0.013
behavior GO:0007610 74 0.013
organelle localization GO:0051640 49 0.013
regulation of gene expression epigenetic GO:0040029 11 0.013
regulation of response to cytokine stimulus GO:0060759 3 0.013
protein complex disassembly GO:0043241 1 0.013
cellular protein catabolic process GO:0044257 4 0.013
intracellular estrogen receptor signaling pathway GO:0030520 3 0.013
transport GO:0006810 220 0.013
Worm
small molecule metabolic process GO:0044281 77 0.013
histone methylation GO:0016571 13 0.013
viral process GO:0016032 1 0.013
response to carbohydrate GO:0009743 3 0.013
cell matrix adhesion GO:0007160 4 0.013
neuron differentiation GO:0030182 353 0.013
tissue regeneration GO:0042246 74 0.013
growth GO:0040007 174 0.013
Worm
leukocyte proliferation GO:0070661 1 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
Human
mitotic dna integrity checkpoint GO:0044774 4 0.013
regulation of multicellular organism growth GO:0040014 4 0.013
Worm
regionalization GO:0003002 274 0.013
stem cell differentiation GO:0048863 117 0.012
mitotic sister chromatid segregation GO:0000070 6 0.012
Human Worm
adherens junction organization GO:0034332 4 0.012
synaptic growth at neuromuscular junction GO:0051124 2 0.012
rna transport GO:0050658 2 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.012
meiotic nuclear division GO:0007126 4 0.012
Worm
negative regulation of signaling GO:0023057 96 0.012
regulation of localization GO:0032879 104 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.012
regulation of cell communication GO:0010646 232 0.012
heterocycle biosynthetic process GO:0018130 215 0.012
mitotic g2 dna damage checkpoint GO:0007095 3 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
muscle cell differentiation GO:0042692 139 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.012
Human
negative regulation of metabolic process GO:0009892 86 0.012
Human
regulation of histone methylation GO:0031060 3 0.012
specification of symmetry GO:0009799 204 0.012
brain development GO:0007420 293 0.012
single organism transport GO:0044765 206 0.012
chemosensory behavior GO:0007635 1 0.012
protein polymerization GO:0051258 4 0.012
cell substrate adherens junction assembly GO:0007045 1 0.012
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.012
Human
positive regulation of rna metabolic process GO:0051254 59 0.012
atp catabolic process GO:0006200 4 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
covalent chromatin modification GO:0016569 20 0.012
neuromuscular synaptic transmission GO:0007274 2 0.012
purine nucleoside monophosphate catabolic process GO:0009128 4 0.011
nucleobase containing compound transport GO:0015931 2 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
negative regulation of defense response GO:0031348 2 0.011
head development GO:0060322 303 0.011
nucleic acid transport GO:0050657 2 0.011
positive regulation of protein complex assembly GO:0031334 2 0.011
modification dependent protein catabolic process GO:0019941 3 0.011
cell surface receptor signaling pathway GO:0007166 325 0.011
biosynthetic process GO:0009058 294 0.011
Human
positive regulation of catabolic process GO:0009896 4 0.011
response to external biotic stimulus GO:0043207 97 0.011
response to ketone GO:1901654 1 0.011
regulation of nucleic acid templated transcription GO:1903506 213 0.011
phosphorylation GO:0016310 69 0.011
neuron projection morphogenesis GO:0048812 161 0.011
wound healing GO:0042060 90 0.011
positive regulation of metabolic process GO:0009893 108 0.011
regulation of rho protein signal transduction GO:0035023 2 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
dna modification GO:0006304 8 0.011
circadian sleep wake cycle sleep GO:0050802 1 0.011
positive regulation of biosynthetic process GO:0009891 68 0.011
cellular response to extracellular stimulus GO:0031668 2 0.011
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.011
positive regulation of histone modification GO:0031058 1 0.011
stem cell proliferation GO:0072089 4 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.010
cellular localization GO:0051641 97 0.010
cellular nitrogen compound biosynthetic process GO:0044271 218 0.010
interspecies interaction between organisms GO:0044419 4 0.010
development of primary female sexual characteristics GO:0046545 4 0.010
protein homooligomerization GO:0051260 3 0.010
neuron development GO:0048666 262 0.010
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.010
ribonucleoside monophosphate catabolic process GO:0009158 4 0.010
spermatid development GO:0007286 2 0.010
gastrulation GO:0007369 208 0.010
hemopoiesis GO:0030097 183 0.010

pds5a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.094
nervous system disease DOID:863 0 0.028
musculoskeletal system disease DOID:17 0 0.018
muscle tissue disease DOID:66 0 0.016
muscular disease DOID:0080000 0 0.016