Danio rerio

0 known processes

pgd

phosphogluconate hydrogenase

(Aliases: fi03d03,zgc:111848,wu:fi03d03,zgc:55585)

pgd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular modified amino acid metabolic process GO:0006575 3 0.342
small molecule metabolic process GO:0044281 77 0.229
Human
organic acid metabolic process GO:0006082 31 0.214
regulation of response to stimulus GO:0048583 269 0.197
response to nicotine GO:0035094 2 0.171
peptide metabolic process GO:0006518 1 0.169
response to nutrient GO:0007584 3 0.157
single organism metabolic process GO:0044710 217 0.155
Human
sulfur compound metabolic process GO:0006790 13 0.146
carboxylic acid metabolic process GO:0019752 22 0.137
cellular amide metabolic process GO:0043603 4 0.134
organic cyclic compound metabolic process GO:1901360 301 0.128
Human
cellular nitrogen compound metabolic process GO:0034641 290 0.128
Human
lipid storage GO:0019915 1 0.122
response to chemical GO:0042221 320 0.120
oxidation reduction process GO:0055114 41 0.111
Human
meiotic nuclear division GO:0007126 4 0.093
regulation of cellular metabolic process GO:0031323 320 0.093
regulation of establishment of protein localization GO:0070201 4 0.092
single organism biosynthetic process GO:0044711 71 0.091
nitrogen compound metabolic process GO:0006807 319 0.090
Human
response to oxidative stress GO:0006979 11 0.087
aging GO:0007568 2 0.086
removal of superoxide radicals GO:0019430 2 0.084
dicarboxylic acid metabolic process GO:0043648 1 0.083
oxoacid metabolic process GO:0043436 31 0.082
nucleic acid metabolic process GO:0090304 244 0.082
response to alkaloid GO:0043279 2 0.075
regulation of primary metabolic process GO:0080090 311 0.074
organonitrogen compound metabolic process GO:1901564 74 0.070
Human
response to inorganic substance GO:0010035 38 0.069
multicellular organism growth GO:0035264 4 0.066
transcription from rna polymerase iii promoter GO:0006383 1 0.066
hydrogen peroxide metabolic process GO:0042743 2 0.064
regulation of biological quality GO:0065008 263 0.064
cofactor metabolic process GO:0051186 15 0.061
Human
negative regulation of cellular process GO:0048523 283 0.061
maintenance of location GO:0051235 4 0.061
regulation of cytokine production GO:0001817 3 0.056
cellular amino acid metabolic process GO:0006520 7 0.056
nucleobase containing compound metabolic process GO:0006139 274 0.053
Human
cellular amine metabolic process GO:0044106 2 0.053
response to vitamin GO:0033273 3 0.048
superoxide metabolic process GO:0006801 2 0.047
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.047
regulation of metabolic process GO:0019222 359 0.046
regulation of multicellular organismal process GO:0051239 277 0.046
organonitrogen compound biosynthetic process GO:1901566 47 0.045
response to hydrogen peroxide GO:0042542 3 0.045
larval development GO:0002164 2 0.044
Worm
organic substance biosynthetic process GO:1901576 289 0.044
endosomal transport GO:0016197 2 0.043
regulation of response to oxidative stress GO:1902882 2 0.042
signal transduction GO:0007165 455 0.042
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.042
response to antibiotic GO:0046677 1 0.041
negative regulation of biological process GO:0048519 304 0.040
cellular biosynthetic process GO:0044249 286 0.040
carboxylic acid catabolic process GO:0046395 3 0.039
immune system process GO:0002376 241 0.039
positive regulation of macromolecule metabolic process GO:0010604 93 0.038
water soluble vitamin metabolic process GO:0006767 1 0.038
leukocyte mediated cytotoxicity GO:0001909 1 0.037
xenobiotic metabolic process GO:0006805 4 0.037
positive regulation of biological process GO:0048518 253 0.036
regulation of cellular response to oxidative stress GO:1900407 2 0.036
small molecule catabolic process GO:0044282 3 0.036
response to external stimulus GO:0009605 264 0.035
cellular protein metabolic process GO:0044267 129 0.034
regulation of intracellular protein transport GO:0033157 3 0.034
positive regulation of catabolic process GO:0009896 4 0.033
regulation of metal ion transport GO:0010959 4 0.033
heterocycle metabolic process GO:0046483 290 0.032
Human
positive regulation of secretion GO:0051047 1 0.032
cellular response to reactive oxygen species GO:0034614 2 0.032
tissue remodeling GO:0048771 4 0.032
heterocycle biosynthetic process GO:0018130 215 0.032
biosynthetic process GO:0009058 294 0.032
homeostasis of number of cells GO:0048872 62 0.032
regulation of macromolecule metabolic process GO:0060255 317 0.032
establishment of protein localization to organelle GO:0072594 4 0.031
regulation of cell motility GO:2000145 46 0.031
oxidoreduction coenzyme metabolic process GO:0006733 1 0.031
Human
response to organic substance GO:0010033 153 0.031
positive regulation of cellular component biogenesis GO:0044089 3 0.030
regulation of binding GO:0051098 3 0.030
phosphate containing compound metabolic process GO:0006796 108 0.030
Human
amine metabolic process GO:0009308 2 0.029
protein metabolic process GO:0019538 183 0.029
phagocytosis engulfment GO:0006911 1 0.029
embryonic organ development GO:0048568 381 0.029
transcription dna templated GO:0006351 181 0.029
homeostatic process GO:0042592 142 0.029
regulation of apoptotic process GO:0042981 98 0.029
phosphorus metabolic process GO:0006793 109 0.028
Human
regulation of blood vessel size GO:0050880 2 0.028
cellular aromatic compound metabolic process GO:0006725 295 0.028
Human
positive regulation of cytokine production GO:0001819 2 0.028
generation of neurons GO:0048699 385 0.028
nucleic acid templated transcription GO:0097659 181 0.027
regulation of cellular amine metabolic process GO:0033238 0 0.027
positive regulation of gtp catabolic process GO:0033126 1 0.027
erythrocyte homeostasis GO:0034101 55 0.027
reactive oxygen species metabolic process GO:0072593 6 0.027
regulation of protein import into nucleus GO:0042306 2 0.026
collagen metabolic process GO:0032963 2 0.026
cellular nitrogen compound biosynthetic process GO:0044271 218 0.025
circulatory system process GO:0003013 87 0.025
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.025
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.024
protein import into nucleus GO:0006606 3 0.024
response to topologically incorrect protein GO:0035966 2 0.024
cation transmembrane transport GO:0098655 65 0.024
positive regulation of transport GO:0051050 2 0.024
nuclear transport GO:0051169 4 0.024
lipid catabolic process GO:0016042 4 0.023
retina development in camera type eye GO:0060041 146 0.023
phagocytosis GO:0006909 3 0.023
cell projection assembly GO:0030031 64 0.023
regulation of programmed cell death GO:0043067 101 0.023
nucleobase containing compound biosynthetic process GO:0034654 205 0.023
regulation of multicellular organism growth GO:0040014 4 0.022
blood circulation GO:0008015 87 0.022
regulation of tube size GO:0035150 2 0.022
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.022
negative regulation of cell death GO:0060548 60 0.022
multi organism process GO:0051704 134 0.022
negative regulation of cellular metabolic process GO:0031324 77 0.022
organic cyclic compound biosynthetic process GO:1901362 223 0.022
programmed cell death GO:0012501 119 0.022
macromolecule biosynthetic process GO:0009059 227 0.021
guanosine containing compound catabolic process GO:1901069 2 0.021
regulation of cell death GO:0010941 103 0.021
negative regulation of protein phosphorylation GO:0001933 4 0.021
cellular response to xenobiotic stimulus GO:0071466 35 0.021
meiotic cell cycle process GO:1903046 3 0.021
regulation of calcium ion transport GO:0051924 2 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.021
response to stress GO:0006950 263 0.020
immune system development GO:0002520 191 0.020
regulation of protein catabolic process GO:0042176 1 0.020
protein import GO:0017038 3 0.020
neurotransmitter transport GO:0006836 2 0.020
hepaticobiliary system development GO:0061008 98 0.020
tube morphogenesis GO:0035239 349 0.019
regulation of protein complex assembly GO:0043254 3 0.019
camera type eye development GO:0043010 222 0.019
regulation of nucleotide catabolic process GO:0030811 2 0.019
regulation of cell activation GO:0050865 1 0.019
immune response GO:0006955 28 0.019
negative regulation of programmed cell death GO:0043069 58 0.019
response to lipid GO:0033993 60 0.019
response to carbohydrate GO:0009743 3 0.019
response to metal ion GO:0010038 34 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
adult behavior GO:0030534 2 0.018
response to organic cyclic compound GO:0014070 51 0.018
inorganic cation transmembrane transport GO:0098662 50 0.018
cellular response to chemical stimulus GO:0070887 157 0.018
regulation of membrane potential GO:0042391 23 0.018
multicellular organismal macromolecule metabolic process GO:0044259 2 0.018
response to xenobiotic stimulus GO:0009410 45 0.018
neuron differentiation GO:0030182 353 0.018
cellular response to topologically incorrect protein GO:0035967 2 0.018
cellular ketone metabolic process GO:0042180 11 0.018
regulation of gtp catabolic process GO:0033124 2 0.018
immune effector process GO:0002252 23 0.018
cell surface receptor signaling pathway GO:0007166 325 0.018
membrane invagination GO:0010324 1 0.017
response to dexamethasone GO:0071548 1 0.017
negative regulation of kinase activity GO:0033673 4 0.017
response to abiotic stimulus GO:0009628 122 0.017
response to unfolded protein GO:0006986 2 0.017
multicellular organismal metabolic process GO:0044236 2 0.017
positive regulation of cellular metabolic process GO:0031325 94 0.017
cellular aldehyde metabolic process GO:0006081 4 0.017
multicellular organismal reproductive process GO:0048609 35 0.017
cell death GO:0008219 121 0.017
cellular response to stress GO:0033554 62 0.016
cellular protein catabolic process GO:0044257 4 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
fatty acid metabolic process GO:0006631 5 0.016
cell part morphogenesis GO:0032990 246 0.016
anatomical structure homeostasis GO:0060249 36 0.016
regulation of molecular function GO:0065009 70 0.016
purine ribonucleotide metabolic process GO:0009150 27 0.016
homeostasis of number of cells within a tissue GO:0048873 4 0.016
positive regulation of multicellular organismal process GO:0051240 52 0.016
regulation of rna biosynthetic process GO:2001141 213 0.016
cellular macromolecule biosynthetic process GO:0034645 224 0.016
regulation of protein transport GO:0051223 3 0.016
cellular macromolecule metabolic process GO:0044260 391 0.016
guanosine containing compound metabolic process GO:1901068 4 0.016
gtp metabolic process GO:0046039 4 0.015
negative regulation of apoptotic process GO:0043066 55 0.015
negative regulation of protein transport GO:0051224 3 0.015
multicellular organismal response to stress GO:0033555 2 0.015
positive regulation of nucleotide catabolic process GO:0030813 1 0.015
fatty acid transport GO:0015908 1 0.015
response to wounding GO:0009611 116 0.015
endoplasmic reticulum unfolded protein response GO:0030968 2 0.015
response to drug GO:0042493 3 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
sexual reproduction GO:0019953 36 0.015
regulation of cytoplasmic transport GO:1903649 4 0.015
i kappab kinase nf kappab signaling GO:0007249 4 0.015
proteolysis GO:0006508 38 0.014
neurotransmitter secretion GO:0007269 2 0.014
regulation of peptidase activity GO:0052547 23 0.014
negative regulation of protein kinase activity GO:0006469 4 0.014
alpha amino acid metabolic process GO:1901605 3 0.014
regulation of cellular biosynthetic process GO:0031326 245 0.014
protein localization to plasma membrane GO:0072659 1 0.014
mitochondrion organization GO:0007005 4 0.014
positive regulation of blood circulation GO:1903524 2 0.014
regulation of cell communication GO:0010646 232 0.014
response to amino acid GO:0043200 2 0.014
locomotion GO:0040011 313 0.014
neuromuscular process controlling balance GO:0050885 3 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
negative regulation of mapk cascade GO:0043409 4 0.014
regulation of reproductive process GO:2000241 4 0.014
cellular response to oxidative stress GO:0034599 5 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
regulation of locomotion GO:0040012 55 0.014
neuron development GO:0048666 262 0.014
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.014
regeneration GO:0031099 91 0.014
liver development GO:0001889 96 0.014
positive regulation of molecular function GO:0044093 33 0.013
gtp catabolic process GO:0006184 2 0.013
response to oxygen containing compound GO:1901700 55 0.013
organelle assembly GO:0070925 110 0.013
rna metabolic process GO:0016070 219 0.013
lytic vacuole organization GO:0080171 1 0.013
eye development GO:0001654 277 0.013
angiogenesis GO:0001525 158 0.013
death GO:0016265 121 0.013
response to amine GO:0014075 1 0.013
regulation of localization GO:0032879 104 0.013
response to monosaccharide GO:0034284 3 0.013
negative regulation of gene expression GO:0010629 65 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
extrinsic apoptotic signaling pathway GO:0097191 3 0.013
nucleocytoplasmic transport GO:0006913 4 0.012
cellular component movement GO:0006928 335 0.012
organic acid catabolic process GO:0016054 3 0.012
peptidyl lysine acetylation GO:0018394 2 0.012
hindbrain development GO:0030902 91 0.012
regulation of cellular ketone metabolic process GO:0010565 7 0.012
single organism localization GO:1902578 225 0.012
cellular component disassembly GO:0022411 1 0.012
response to amphetamine GO:0001975 1 0.012
negative regulation of jnk cascade GO:0046329 1 0.012
negative regulation of heart contraction GO:0045822 2 0.012
cell death in response to oxidative stress GO:0036473 2 0.012
aromatic compound biosynthetic process GO:0019438 217 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
cell projection morphogenesis GO:0048858 244 0.012
regulation of intracellular ph GO:0051453 1 0.011
vasculature development GO:0001944 278 0.011
phagolysosome assembly GO:0001845 1 0.011
positive regulation of cell activation GO:0050867 1 0.011
regulation of immune system process GO:0002682 34 0.011
central nervous system development GO:0007417 387 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
cellular component biogenesis GO:0044085 178 0.011
cell projection organization GO:0030030 284 0.011
negative regulation of transcription dna templated GO:0045892 45 0.011
regulation of cell migration GO:0030334 40 0.011
internal protein amino acid acetylation GO:0006475 2 0.011
positive regulation of dna metabolic process GO:0051054 1 0.011
digestive tract morphogenesis GO:0048546 231 0.011
negative regulation of metabolic process GO:0009892 86 0.011
startle response GO:0001964 4 0.011
synaptic transmission cholinergic GO:0007271 4 0.011
muscle structure development GO:0061061 196 0.011
long chain fatty acid metabolic process GO:0001676 1 0.011
actin polymerization or depolymerization GO:0008154 2 0.011
organic substance transport GO:0071702 58 0.011
regulation of ph GO:0006885 3 0.011
carbohydrate derivative biosynthetic process GO:1901137 43 0.011
er nucleus signaling pathway GO:0006984 2 0.011
regulation of gtpase activity GO:0043087 2 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.010
positive regulation of nucleoside metabolic process GO:0045979 1 0.010
transmembrane transport GO:0055085 120 0.010
blood vessel development GO:0001568 246 0.010
ph reduction GO:0045851 1 0.010
protein homooligomerization GO:0051260 3 0.010
regulation of transcription dna templated GO:0006355 213 0.010
regulation of sodium ion transmembrane transport GO:1902305 1 0.010
ion transmembrane transport GO:0034220 91 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.010
regulation of blood pressure GO:0008217 1 0.010
calcium ion transport into cytosol GO:0060402 3 0.010
fatty acid biosynthetic process GO:0006633 4 0.010
positive regulation of cellular process GO:0048522 201 0.010

pgd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.053
disease of metabolism DOID:0014667 0 0.033
inherited metabolic disorder DOID:655 0 0.033
nervous system disease DOID:863 0 0.020
disease of cellular proliferation DOID:14566 0 0.015
immune system disease DOID:2914 0 0.013