Danio rerio

13 known processes

pglyrp2

peptidoglycan recognition protein 2

(Aliases: pgrp-l)

pglyrp2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
defense response to other organism GO:0098542 33 0.444
response to other organism GO:0051707 97 0.401
ganglioside metabolic process GO:0001573 3 0.312
response to bacterium GO:0009617 58 0.279
steroid hormone secretion GO:0035929 1 0.255
defense response to bacterium GO:0042742 22 0.232
multi organism process GO:0051704 134 0.200
response to external biotic stimulus GO:0043207 97 0.186
blood vessel development GO:0001568 246 0.152
positive regulation of epithelial cell differentiation GO:0030858 2 0.150
response to biotic stimulus GO:0009607 97 0.147
defense response GO:0006952 47 0.144
muscle structure development GO:0061061 196 0.142
ectodermal placode morphogenesis GO:0071697 32 0.142
response to external stimulus GO:0009605 264 0.136
segmentation GO:0035282 97 0.126
lipid oxidation GO:0034440 1 0.126
xenobiotic metabolic process GO:0006805 4 0.121
anterior posterior axis specification GO:0009948 20 0.106
digestive system development GO:0055123 289 0.103
meiosis ii GO:0007135 1 0.103
determination of bilateral symmetry GO:0009855 204 0.095
embryonic organ morphogenesis GO:0048562 274 0.092
fatty acid catabolic process GO:0009062 1 0.087
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.080
developmental cell growth GO:0048588 52 0.078
heart looping GO:0001947 94 0.078
pole plasm assembly GO:0007315 4 0.074
determination of left right symmetry GO:0007368 179 0.071
convergent extension GO:0060026 118 0.065
vasculature development GO:0001944 278 0.064
positive regulation of cellular catabolic process GO:0031331 3 0.064
response to drug GO:0042493 3 0.062
cellular protein metabolic process GO:0044267 129 0.061
anterior posterior pattern specification GO:0009952 152 0.060
regulation of epithelial cell proliferation GO:0050678 3 0.059
ectodermal placode development GO:0071696 37 0.058
oocyte differentiation GO:0009994 14 0.058
morphogenesis of an epithelium GO:0002009 333 0.058
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.056
positive regulation of cell cycle GO:0045787 3 0.056
heart development GO:0007507 313 0.056
blood vessel morphogenesis GO:0048514 216 0.054
sulfur compound metabolic process GO:0006790 13 0.050
negative regulation of mitosis GO:0045839 3 0.050
enzyme linked receptor protein signaling pathway GO:0007167 106 0.050
negative regulation of nuclear division GO:0051784 3 0.050
cellular macromolecule metabolic process GO:0044260 391 0.048
response to stress GO:0006950 263 0.048
muscle cell development GO:0055001 115 0.048
hepatocyte proliferation GO:0072574 2 0.047
regulation of cell development GO:0060284 100 0.046
regulation of mrna processing GO:0050684 3 0.046
specification of symmetry GO:0009799 204 0.044
positive regulation of chromosome segregation GO:0051984 1 0.044
organic cyclic compound metabolic process GO:1901360 301 0.044
positive regulation of catabolic process GO:0009896 4 0.043
stem cell maintenance GO:0019827 4 0.042
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.041
regulation of developmental process GO:0050793 247 0.041
Mouse
oocyte anterior posterior axis specification GO:0007314 4 0.040
regulation of signaling GO:0023051 235 0.040
embryonic heart tube development GO:0035050 133 0.039
biosynthetic process GO:0009058 294 0.038
embryonic heart tube morphogenesis GO:0003143 108 0.038
notochord development GO:0030903 54 0.038
stem cell fate commitment GO:0048865 1 0.037
liver development GO:0001889 96 0.037
mediolateral intercalation GO:0060031 3 0.037
regionalization GO:0003002 274 0.035
larval development GO:0002164 2 0.035
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.034
pectoral fin morphogenesis GO:0035138 29 0.034
regulation of oocyte development GO:0060281 3 0.033
sialylation GO:0097503 4 0.033
optic placode formation GO:0001743 4 0.033
golgi vesicle transport GO:0048193 3 0.033
cellular response to xenobiotic stimulus GO:0071466 35 0.033
female sex differentiation GO:0046660 4 0.032
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.032
regulation of reproductive process GO:2000241 4 0.032
membrane lipid biosynthetic process GO:0046467 2 0.032
ectoderm development GO:0007398 9 0.031
release of sequestered calcium ion into cytosol GO:0051209 3 0.031
camera type eye development GO:0043010 222 0.031
regulation of cellular amine metabolic process GO:0033238 0 0.031
pancreas development GO:0031016 84 0.031
cell migration GO:0016477 237 0.031
lateral line development GO:0048882 66 0.031
regulation of chromosome segregation GO:0051983 1 0.030
embryonic foregut morphogenesis GO:0048617 1 0.030
maternal determination of anterior posterior axis embryo GO:0008358 4 0.030
hepaticobiliary system development GO:0061008 98 0.030
regulation of endocrine process GO:0044060 2 0.030
multicellular organism growth GO:0035264 4 0.029
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.029
thrombocyte differentiation GO:0002574 4 0.029
regulation of embryonic development GO:0045995 47 0.029
meiosis i GO:0007127 1 0.029
negative regulation of kinase activity GO:0033673 4 0.028
regulation of anterior head development GO:2000742 2 0.028
gall bladder development GO:0061010 1 0.028
eye development GO:0001654 277 0.028
cell death GO:0008219 121 0.028
epithelial tube morphogenesis GO:0060562 148 0.028
cell cycle GO:0007049 93 0.028
regulation of mrna splicing via spliceosome GO:0048024 3 0.028
cytoplasm organization GO:0007028 4 0.027
nitrogen compound metabolic process GO:0006807 319 0.027
er to golgi vesicle mediated transport GO:0006888 1 0.027
amine metabolic process GO:0009308 2 0.027
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.027
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.026
neuromast development GO:0048884 46 0.026
neuron projection extension GO:1990138 45 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
antimicrobial humoral response GO:0019730 2 0.026
positive regulation of biological process GO:0048518 253 0.026
muscle organ development GO:0007517 101 0.026
alternative mrna splicing via spliceosome GO:0000380 1 0.026
cell projection morphogenesis GO:0048858 244 0.026
positive regulation of cell division GO:0051781 2 0.025
membrane lipid metabolic process GO:0006643 10 0.025
rna localization GO:0006403 4 0.025
fatty acid beta oxidation GO:0006635 1 0.025
rna metabolic process GO:0016070 219 0.024
oogenesis GO:0048477 14 0.024
oocyte maturation GO:0001556 4 0.024
sphingolipid biosynthetic process GO:0030148 2 0.024
embryonic digestive tract morphogenesis GO:0048557 3 0.024
g2 m transition of mitotic cell cycle GO:0000086 4 0.024
muscle fiber development GO:0048747 52 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.023
regulation of jun kinase activity GO:0043506 3 0.023
anterior posterior axis specification embryo GO:0008595 5 0.023
positive regulation of epithelial cell proliferation GO:0050679 1 0.023
negative regulation of stem cell differentiation GO:2000737 2 0.022
mitotic cell cycle GO:0000278 64 0.022
glycosphingolipid biosynthetic process GO:0006688 1 0.022
regulation of cellular ketone metabolic process GO:0010565 7 0.022
organelle localization GO:0051640 49 0.022
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.022
regulation of protein polymerization GO:0032271 2 0.022
skeletal system development GO:0001501 181 0.021
cell fate specification involved in pattern specification GO:0060573 3 0.021
nuclear migration GO:0007097 3 0.021
spindle assembly GO:0051225 2 0.021
positive regulation of signaling GO:0023056 56 0.021
humoral immune response mediated by circulating immunoglobulin GO:0002455 3 0.021
cell fate specification GO:0001708 68 0.021
tissue regeneration GO:0042246 74 0.021
oocyte development GO:0048599 14 0.021
cellular amine metabolic process GO:0044106 2 0.021
positive regulation of transport GO:0051050 2 0.021
positive regulation of embryonic development GO:0040019 3 0.021
regulation of steroid hormone secretion GO:2000831 1 0.021
hepatic duct development GO:0061011 2 0.020
bmp signaling pathway GO:0030509 52 0.020
stem cell differentiation GO:0048863 117 0.020
pectoral fin development GO:0033339 50 0.020
regulation of neuron projection development GO:0010975 40 0.020
camera type eye morphogenesis GO:0048593 108 0.020
immunoglobulin mediated immune response GO:0016064 3 0.020
dorsal ventral pattern formation GO:0009953 125 0.020
defense response to gram positive bacterium GO:0050830 6 0.020
maintenance of location GO:0051235 4 0.019
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.019
regulation of cellular response to growth factor stimulus GO:0090287 35 0.019
positive regulation of translation GO:0045727 1 0.019
regulation of multicellular organismal development GO:2000026 223 0.019
Mouse
positive regulation of mrna metabolic process GO:1903313 2 0.019
negative regulation of protein kinase activity GO:0006469 4 0.019
cell migration involved in gastrulation GO:0042074 79 0.019
regulation of mrna catabolic process GO:0061013 3 0.019
organelle organization GO:0006996 227 0.019
tube morphogenesis GO:0035239 349 0.019
embryo development ending in birth or egg hatching GO:0009792 271 0.019
regulation of endothelial cell differentiation GO:0045601 3 0.018
cellular protein catabolic process GO:0044257 4 0.018
somite development GO:0061053 96 0.018
embryonic cranial skeleton morphogenesis GO:0048701 90 0.018
regulation of meiotic cell cycle GO:0051445 1 0.018
embryonic appendage morphogenesis GO:0035113 30 0.018
striated muscle cell development GO:0055002 108 0.018
heart morphogenesis GO:0003007 156 0.018
spindle assembly involved in meiosis GO:0090306 1 0.018
hair cell differentiation GO:0035315 32 0.018
macromolecule biosynthetic process GO:0009059 227 0.018
embryonic skeletal system development GO:0048706 97 0.018
negative regulation of protein phosphorylation GO:0001933 4 0.018
regulation of metabolic process GO:0019222 359 0.017
carbohydrate homeostasis GO:0033500 1 0.017
nucleobase containing compound metabolic process GO:0006139 274 0.017
nephron tubule morphogenesis GO:0072078 1 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.017
monoamine transport GO:0015844 1 0.017
somitogenesis GO:0001756 87 0.017
regulation of macromolecule metabolic process GO:0060255 317 0.017
response to nutrient GO:0007584 3 0.017
cellular response to hypoxia GO:0071456 1 0.017
activation of mapk activity GO:0000187 3 0.017
nucleic acid metabolic process GO:0090304 244 0.017
embryonic organ development GO:0048568 381 0.017
neural plate anterior posterior regionalization GO:0021999 8 0.017
negative regulation of defense response GO:0031348 2 0.017
alpha amino acid metabolic process GO:1901605 3 0.017
optic placode formation involved in camera type eye formation GO:0046619 3 0.016
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.016
regulation of homeostatic process GO:0032844 9 0.016
regulation of gene expression GO:0010468 265 0.016
protein modification process GO:0036211 100 0.016
negative regulation of immune response GO:0050777 2 0.016
Mouse
regulation of primary metabolic process GO:0080090 311 0.016
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.016
embryonic digestive tract development GO:0048566 4 0.016
positive regulation of lipid metabolic process GO:0045834 1 0.016
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.016
cellular response to external stimulus GO:0071496 2 0.016
foregut morphogenesis GO:0007440 4 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
mrna transport GO:0051028 2 0.015
regulation of stem cell proliferation GO:0072091 2 0.015
positive regulation of signal transduction GO:0009967 56 0.015
regulation of carbohydrate metabolic process GO:0006109 4 0.015
cellular response to oxygen levels GO:0071453 1 0.015
anterior head development GO:0097065 2 0.015
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.015
protein metabolic process GO:0019538 183 0.015
embryonic limb morphogenesis GO:0030326 2 0.015
cellular protein modification process GO:0006464 100 0.015
regulation of cellular metabolic process GO:0031323 320 0.015
oocyte growth GO:0001555 1 0.015
phosphate containing compound metabolic process GO:0006796 108 0.015
gastrulation with mouth forming second GO:0001702 44 0.015
single organism metabolic process GO:0044710 217 0.015
single organism transport GO:0044765 206 0.015
regulation of anatomical structure morphogenesis GO:0022603 130 0.015
sensory system development GO:0048880 76 0.015
retina morphogenesis in camera type eye GO:0060042 79 0.014
cranial nerve development GO:0021545 42 0.014
myeloid leukocyte migration GO:0097529 12 0.014
purine nucleoside monophosphate catabolic process GO:0009128 4 0.014
female gonad development GO:0008585 4 0.014
regulation of stem cell differentiation GO:2000736 4 0.014
positive regulation of cytoskeleton organization GO:0051495 3 0.014
oxoacid metabolic process GO:0043436 31 0.014
fin morphogenesis GO:0033334 53 0.014
response to copper ion GO:0046688 13 0.014
protein polymerization GO:0051258 4 0.014
muscle tissue development GO:0060537 110 0.014
transport GO:0006810 220 0.014
neuroblast fate commitment GO:0014017 1 0.014
spermatid development GO:0007286 2 0.014
fatty acid oxidation GO:0019395 1 0.014
endocrine process GO:0050886 2 0.014
forebrain development GO:0030900 96 0.014
regulation of protein complex assembly GO:0043254 3 0.014
female gamete generation GO:0007292 14 0.013
cellular response to starvation GO:0009267 1 0.013
retina development in camera type eye GO:0060041 146 0.013
germ line stem cell maintenance GO:0030718 2 0.013
membrane invagination GO:0010324 1 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.013
positive regulation of chromatin modification GO:1903310 1 0.013
eye photoreceptor cell development GO:0042462 30 0.013
ectodermal placode formation GO:0060788 26 0.013
appendage morphogenesis GO:0035107 56 0.013
muscle cell differentiation GO:0042692 139 0.013
stem cell division GO:0017145 1 0.013
embryonic skeletal system morphogenesis GO:0048704 93 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
regulation of fatty acid metabolic process GO:0019217 1 0.013
liver morphogenesis GO:0072576 8 0.013
positive regulation of gene expression GO:0010628 71 0.013
negative regulation of oocyte development GO:0060283 2 0.013
regulation of epithelial to mesenchymal transition GO:0010717 3 0.013
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.013
establishment of localization GO:0051234 244 0.013
establishment of organelle localization GO:0051656 45 0.013
positive regulation of endothelial cell differentiation GO:0045603 2 0.013
germ line stem cell division GO:0042078 1 0.013
nephron morphogenesis GO:0072028 2 0.013
ion homeostasis GO:0050801 41 0.012
cell cell signaling GO:0007267 52 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
ceramide biosynthetic process GO:0046513 1 0.012
skeletal system morphogenesis GO:0048705 102 0.012
autophagy GO:0006914 4 0.012
response to xenobiotic stimulus GO:0009410 45 0.012
positive regulation of cellular component biogenesis GO:0044089 3 0.012
complement activation GO:0006956 3 0.012
cellular lipid metabolic process GO:0044255 36 0.012
nucleic acid templated transcription GO:0097659 181 0.012
nucleic acid transport GO:0050657 2 0.012
positive regulation of map kinase activity GO:0043406 3 0.012
l amino acid transport GO:0015807 1 0.012
glycolipid biosynthetic process GO:0009247 1 0.012
spermatid differentiation GO:0048515 2 0.012
liposaccharide metabolic process GO:1903509 8 0.012
carbohydrate biosynthetic process GO:0016051 1 0.012
death GO:0016265 121 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.012
Mouse
regulation of glial cell differentiation GO:0045685 4 0.012
mesenchyme development GO:0060485 127 0.012
appendage development GO:0048736 80 0.012
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 9 0.012
cell substrate adhesion GO:0031589 4 0.011
cell part morphogenesis GO:0032990 246 0.011
angiogenesis GO:0001525 158 0.011
chordate embryonic development GO:0043009 271 0.011
connective tissue development GO:0061448 99 0.011
cytokinesis GO:0000910 3 0.011
sequestering of calcium ion GO:0051208 3 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
positive regulation of jnk cascade GO:0046330 3 0.011
neurotransmitter transport GO:0006836 2 0.011
cellular lipid catabolic process GO:0044242 3 0.011
response to chemical GO:0042221 320 0.011
ovulation cycle process GO:0022602 2 0.011
regulation of protein catabolic process GO:0042176 1 0.011
regulation of extent of cell growth GO:0061387 29 0.011
digestive tract morphogenesis GO:0048546 231 0.011
olfactory placode development GO:0071698 12 0.011
neuroblast differentiation GO:0014016 1 0.011
meiotic chromosome segregation GO:0045132 3 0.011
cellular modified amino acid metabolic process GO:0006575 3 0.011
negative regulation of biological process GO:0048519 304 0.011
Mouse
cellular component assembly GO:0022607 170 0.011
regulation of sequestering of calcium ion GO:0051282 4 0.011
cell surface receptor signaling pathway GO:0007166 325 0.011
positive regulation of transcription dna templated GO:0045893 57 0.011
hormone secretion GO:0046879 2 0.011
actin filament polymerization GO:0030041 2 0.011
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.011
single organism localization GO:1902578 225 0.011
signal transduction GO:0007165 455 0.011
microtubule depolymerization GO:0007019 1 0.011
post anal tail morphogenesis GO:0036342 19 0.011
rhombomere 6 development GO:0021572 4 0.011
cardiocyte differentiation GO:0035051 44 0.011
mitotic nuclear division GO:0007067 18 0.011
sequestering of metal ion GO:0051238 3 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.011
somatic stem cell maintenance GO:0035019 1 0.011
regulation of protein transport GO:0051223 3 0.011
regulation of biological quality GO:0065008 263 0.010
regulation of multicellular organismal process GO:0051239 277 0.010
Mouse
single organism carbohydrate metabolic process GO:0044723 12 0.010
regulation of photoreceptor cell differentiation GO:0046532 2 0.010
positive regulation of muscle organ development GO:0048636 1 0.010
negative regulation of chromosome organization GO:2001251 1 0.010
sensory organ morphogenesis GO:0090596 200 0.010
zymogen activation GO:0031638 3 0.010
cellular response to reactive oxygen species GO:0034614 2 0.010
canonical wnt signaling pathway GO:0060070 48 0.010
regulation of cell communication GO:0010646 232 0.010
proximal distal pattern formation GO:0009954 1 0.010
positive regulation of histone modification GO:0031058 1 0.010
blastoderm segmentation GO:0007350 6 0.010
oocyte axis specification GO:0007309 5 0.010

pglyrp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.048
inherited metabolic disorder DOID:655 0 0.020
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010