Danio rerio

0 known processes

phactr4b

phosphatase and actin regulator 4b

(Aliases: zgc:63484,phactr4,MGC63484)

phactr4b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.415
organic substance biosynthetic process GO:1901576 289 0.223
macromolecule biosynthetic process GO:0009059 227 0.196
organic cyclic compound metabolic process GO:1901360 301 0.195
regulation of metabolic process GO:0019222 359 0.172
regulation of gene expression GO:0010468 265 0.165
nitrogen compound metabolic process GO:0006807 319 0.160
cellular nitrogen compound metabolic process GO:0034641 290 0.132
negative regulation of biological process GO:0048519 304 0.131
nucleic acid metabolic process GO:0090304 244 0.128
cellular aromatic compound metabolic process GO:0006725 295 0.124
biosynthetic process GO:0009058 294 0.123
regulation of biosynthetic process GO:0009889 250 0.120
response to stress GO:0006950 263 0.114
nucleobase containing compound metabolic process GO:0006139 274 0.114
positive regulation of jun kinase activity GO:0043507 2 0.113
cellular macromolecule metabolic process GO:0044260 391 0.105
cellular component movement GO:0006928 335 0.103
embryo development ending in birth or egg hatching GO:0009792 271 0.103
regulation of macromolecule biosynthetic process GO:0010556 225 0.099
cell migration GO:0016477 237 0.099
cellular biosynthetic process GO:0044249 286 0.097
gene expression GO:0010467 252 0.096
heterocycle biosynthetic process GO:0018130 215 0.095
heterocycle metabolic process GO:0046483 290 0.092
regulation of nucleic acid templated transcription GO:1903506 213 0.092
rna metabolic process GO:0016070 219 0.090
aromatic compound biosynthetic process GO:0019438 217 0.090
cellular macromolecule biosynthetic process GO:0034645 224 0.089
regulation of nitrogen compound metabolic process GO:0051171 251 0.087
positive regulation of biological process GO:0048518 253 0.085
stem cell maintenance GO:0019827 4 0.080
cellular nitrogen compound biosynthetic process GO:0044271 218 0.079
multi organism process GO:0051704 134 0.079
localization of cell GO:0051674 244 0.078
rna biosynthetic process GO:0032774 181 0.075
regulation of cellular metabolic process GO:0031323 320 0.072
regulation of cellular biosynthetic process GO:0031326 245 0.070
regulation of jun kinase activity GO:0043506 3 0.068
heart development GO:0007507 313 0.068
positive regulation of cellular process GO:0048522 201 0.067
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.067
locomotion GO:0040011 313 0.064
polarized epithelial cell differentiation GO:0030859 4 0.064
negative regulation of signaling GO:0023057 96 0.064
cellular component biogenesis GO:0044085 178 0.063
regulation of primary metabolic process GO:0080090 311 0.061
negative regulation of cellular process GO:0048523 283 0.057
regulation of transcription dna templated GO:0006355 213 0.057
response to chemical GO:0042221 320 0.056
nucleobase containing compound biosynthetic process GO:0034654 205 0.056
positive regulation of jnk cascade GO:0046330 3 0.055
transcription dna templated GO:0006351 181 0.053
regulation of biological quality GO:0065008 263 0.053
regulation of macromolecule metabolic process GO:0060255 317 0.053
negative regulation of synapse assembly GO:0051964 2 0.053
development of primary female sexual characteristics GO:0046545 4 0.051
regulation of rna metabolic process GO:0051252 224 0.051
reproductive process GO:0022414 40 0.050
cellular response to chemical stimulus GO:0070887 157 0.049
oxoacid metabolic process GO:0043436 31 0.046
positive regulation of cellular biosynthetic process GO:0031328 68 0.046
response to drug GO:0042493 3 0.045
regulation of signal transduction GO:0009966 225 0.045
negative regulation of signal transduction GO:0009968 94 0.045
central nervous system development GO:0007417 387 0.044
cellular amino acid metabolic process GO:0006520 7 0.044
regulation of cell communication GO:0010646 232 0.044
digestive tract development GO:0048565 265 0.044
digestive system development GO:0055123 289 0.043
cell motility GO:0048870 244 0.043
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.043
positive regulation of map kinase activity GO:0043406 3 0.042
negative regulation of cell communication GO:0010648 96 0.042
lipid storage GO:0019915 1 0.041
female sex differentiation GO:0046660 4 0.041
positive regulation of rna metabolic process GO:0051254 59 0.041
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.040
positive regulation of stress activated mapk cascade GO:0032874 3 0.040
cellular amine metabolic process GO:0044106 2 0.040
cellular protein metabolic process GO:0044267 129 0.040
cellular protein modification process GO:0006464 100 0.039
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.039
response to external stimulus GO:0009605 264 0.039
organic acid metabolic process GO:0006082 31 0.038
positive regulation of cellular metabolic process GO:0031325 94 0.038
g1 s transition of mitotic cell cycle GO:0000082 1 0.038
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.038
carboxylic acid metabolic process GO:0019752 22 0.038
positive regulation of transcription dna templated GO:0045893 57 0.037
aging GO:0007568 2 0.037
negative regulation of kinase activity GO:0033673 4 0.037
generation of neurons GO:0048699 385 0.036
actin cytoskeleton organization GO:0030036 63 0.036
brain development GO:0007420 293 0.035
single organism metabolic process GO:0044710 217 0.035
regulation of synapse assembly GO:0051963 3 0.034
stem cell differentiation GO:0048863 117 0.034
lamellipodium assembly GO:0030032 1 0.034
nucleic acid templated transcription GO:0097659 181 0.034
stem cell division GO:0017145 1 0.034
protein modification process GO:0036211 100 0.033
positive regulation of macromolecule metabolic process GO:0010604 93 0.033
regulation of establishment of protein localization GO:0070201 4 0.033
transcription from rna polymerase ii promoter GO:0006366 80 0.033
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.032
regulation of developmental process GO:0050793 247 0.031
positive regulation of rna biosynthetic process GO:1902680 57 0.031
cell cycle GO:0007049 93 0.031
regulation of cellular ketone metabolic process GO:0010565 7 0.030
regulation of rna biosynthetic process GO:2001141 213 0.030
amine metabolic process GO:0009308 2 0.030
regulation of stem cell differentiation GO:2000736 4 0.030
regulation of multicellular organismal process GO:0051239 277 0.029
positive regulation of metabolic process GO:0009893 108 0.028
regulation of cellular amino acid metabolic process GO:0006521 0 0.028
signal transduction GO:0007165 455 0.028
regulation of cellular amine metabolic process GO:0033238 0 0.028
behavior GO:0007610 74 0.028
vasculature development GO:0001944 278 0.028
negative regulation of response to stimulus GO:0048585 104 0.028
blood vessel morphogenesis GO:0048514 216 0.028
regulation of multicellular organism growth GO:0040014 4 0.028
extrinsic apoptotic signaling pathway GO:0097191 3 0.027
phagocytosis GO:0006909 3 0.027
modification dependent protein catabolic process GO:0019941 3 0.027
regulation of establishment or maintenance of cell polarity GO:0032878 2 0.027
organelle organization GO:0006996 227 0.027
negative regulation of protein phosphorylation GO:0001933 4 0.027
negative regulation of protein kinase activity GO:0006469 4 0.027
chordate embryonic development GO:0043009 271 0.027
positive regulation of biosynthetic process GO:0009891 68 0.027
synaptic target recognition GO:0008039 1 0.026
single organism organelle organization GO:1902589 199 0.026
epithelial cell differentiation GO:0030855 116 0.026
enzyme linked receptor protein signaling pathway GO:0007167 106 0.026
regulation of signaling GO:0023051 235 0.026
lamellipodium organization GO:0097581 1 0.026
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.026
programmed cell death GO:0012501 119 0.025
regulation of response to stimulus GO:0048583 269 0.025
regulation of multicellular organismal development GO:2000026 223 0.025
death GO:0016265 121 0.024
protein polymerization GO:0051258 4 0.024
meiotic nuclear division GO:0007126 4 0.024
organic cyclic compound biosynthetic process GO:1901362 223 0.024
axonogenesis GO:0007409 152 0.024
negative regulation of macromolecule metabolic process GO:0010605 76 0.024
taxis GO:0042330 109 0.023
positive regulation of nucleic acid templated transcription GO:1903508 57 0.023
blood vessel development GO:0001568 246 0.023
positive regulation of gene expression GO:0010628 71 0.023
protein metabolic process GO:0019538 183 0.022
multicellular organism growth GO:0035264 4 0.022
cellular ketone metabolic process GO:0042180 11 0.022
cell substrate adhesion GO:0031589 4 0.022
regionalization GO:0003002 274 0.022
cell cycle g1 s phase transition GO:0044843 1 0.022
germ cell development GO:0007281 22 0.022
positive regulation of cell activation GO:0050867 1 0.022
negative regulation of multicellular organismal process GO:0051241 69 0.021
response to biotic stimulus GO:0009607 97 0.021
immune system process GO:0002376 241 0.021
positive regulation of transport GO:0051050 2 0.021
determination of bilateral symmetry GO:0009855 204 0.021
apoptotic process GO:0006915 116 0.021
negative regulation of cell differentiation GO:0045596 46 0.021
modification dependent macromolecule catabolic process GO:0043632 3 0.021
phosphorus metabolic process GO:0006793 109 0.021
actin filament based process GO:0030029 64 0.021
cellular protein catabolic process GO:0044257 4 0.021
somatic stem cell maintenance GO:0035019 1 0.021
skeletal system development GO:0001501 181 0.021
meiotic cell cycle process GO:1903046 3 0.020
cytokinesis GO:0000910 3 0.020
cell projection organization GO:0030030 284 0.020
autophagy GO:0006914 4 0.020
tube morphogenesis GO:0035239 349 0.020
cell surface receptor signaling pathway GO:0007166 325 0.020
activation of mapk activity GO:0000187 3 0.020
negative regulation of metabolic process GO:0009892 86 0.020
organonitrogen compound metabolic process GO:1901564 74 0.020
female gonad development GO:0008585 4 0.020
nuclear transport GO:0051169 4 0.020
positive regulation of cytoskeleton organization GO:0051495 3 0.019
regulation of cell activation GO:0050865 1 0.019
positive regulation of catabolic process GO:0009896 4 0.019
regulation of stem cell proliferation GO:0072091 2 0.019
maintenance of location GO:0051235 4 0.019
mitotic cell cycle GO:0000278 64 0.019
phosphate containing compound metabolic process GO:0006796 108 0.019
regulation of establishment of planar polarity GO:0090175 4 0.019
cellular response to organic substance GO:0071310 105 0.018
negative chemotaxis GO:0050919 1 0.018
response to abiotic stimulus GO:0009628 122 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.018
establishment of localization GO:0051234 244 0.018
production of molecular mediator of immune response GO:0002440 2 0.018
negative regulation of stem cell differentiation GO:2000737 2 0.018
response to other organism GO:0051707 97 0.018
embryonic organ development GO:0048568 381 0.018
determination of left right symmetry GO:0007368 179 0.018
regulation of synapse organization GO:0050807 3 0.018
leukocyte proliferation GO:0070661 1 0.018
head development GO:0060322 303 0.018
single organism nuclear import GO:1902593 3 0.018
stem cell development GO:0048864 82 0.018
negative regulation of gene expression GO:0010629 65 0.017
nucleocytoplasmic transport GO:0006913 4 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.017
regulation of reproductive process GO:2000241 4 0.017
epithelial tube morphogenesis GO:0060562 148 0.017
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
response to monosaccharide GO:0034284 3 0.017
cytoskeleton organization GO:0007010 96 0.017
ribonucleoside monophosphate catabolic process GO:0009158 4 0.017
negative regulation of cellular metabolic process GO:0031324 77 0.017
digestive tract morphogenesis GO:0048546 231 0.016
regulation of cell differentiation GO:0045595 142 0.016
stem cell proliferation GO:0072089 4 0.016
cellular response to endogenous stimulus GO:0071495 68 0.016
growth GO:0040007 174 0.016
negative regulation of developmental process GO:0051093 65 0.016
response to carbohydrate GO:0009743 3 0.016
protein localization to nucleus GO:0034504 3 0.016
cell projection morphogenesis GO:0048858 244 0.016
morphogenesis of an epithelium GO:0002009 333 0.016
chemotaxis GO:0006935 104 0.016
negative regulation of cellular biosynthetic process GO:0031327 55 0.015
circulatory system process GO:0003013 87 0.015
spermatid development GO:0007286 2 0.015
cellular component disassembly GO:0022411 1 0.015
primary neural tube formation GO:0014020 1 0.015
ubiquitin dependent protein catabolic process GO:0006511 3 0.015
muscle structure development GO:0061061 196 0.015
cell morphogenesis involved in differentiation GO:0000904 195 0.015
synaptic growth at neuromuscular junction GO:0051124 2 0.015
regulation of meiotic cell cycle GO:0051445 1 0.015
histone h3 k4 methylation GO:0051568 2 0.015
cell projection assembly GO:0030031 64 0.015
multi organism reproductive process GO:0044703 36 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.014
immune system development GO:0002520 191 0.014
response to organic substance GO:0010033 153 0.014
regulation of protein complex assembly GO:0043254 3 0.014
macromolecular complex assembly GO:0065003 35 0.014
segmentation GO:0035282 97 0.014
regulation of locomotion GO:0040012 55 0.014
microtubule based process GO:0007017 60 0.014
regulation of cellular component movement GO:0051270 55 0.014
cell morphogenesis GO:0000902 289 0.014
muscle cell differentiation GO:0042692 139 0.014
cognition GO:0050890 1 0.014
cellular response to external stimulus GO:0071496 2 0.014
small molecule metabolic process GO:0044281 77 0.014
response to hexose GO:0009746 3 0.014
internal protein amino acid acetylation GO:0006475 2 0.014
proteasomal protein catabolic process GO:0010498 2 0.014
response to glucose GO:0009749 3 0.014
neuron development GO:0048666 262 0.014
regulation of system process GO:0044057 40 0.014
neuron differentiation GO:0030182 353 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
protein stabilization GO:0050821 2 0.014
organelle assembly GO:0070925 110 0.014
regulation of protein metabolic process GO:0051246 56 0.013
establishment of protein localization to organelle GO:0072594 4 0.013
regulation of protein catabolic process GO:0042176 1 0.013
response to external biotic stimulus GO:0043207 97 0.013
dorsal ventral pattern formation GO:0009953 125 0.013
actin filament polymerization GO:0030041 2 0.013
developmental process involved in reproduction GO:0003006 27 0.013
cardiac cell fate commitment GO:0060911 1 0.013
endosomal transport GO:0016197 2 0.013
specification of organ identity GO:0010092 2 0.013
response to endogenous stimulus GO:0009719 83 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
adult behavior GO:0030534 2 0.013
cell death GO:0008219 121 0.013
homeostatic process GO:0042592 142 0.013
macromolecular complex subunit organization GO:0043933 74 0.013
regulation of neural precursor cell proliferation GO:2000177 3 0.013
cell proliferation GO:0008283 80 0.013
regulation of glucose transport GO:0010827 1 0.013
gamete generation GO:0007276 33 0.013
membrane lipid biosynthetic process GO:0046467 2 0.012
detection of stimulus involved in sensory perception GO:0050906 21 0.012
cell migration involved in gastrulation GO:0042074 79 0.012
chemosensory behavior GO:0007635 1 0.012
protein heterooligomerization GO:0051291 1 0.012
olfactory lobe development GO:0021988 4 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.012
glucose import GO:0046323 2 0.012
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.012
gastrulation GO:0007369 208 0.012
positive regulation of catalytic activity GO:0043085 25 0.012
myeloid cell differentiation GO:0030099 86 0.012
intracellular signal transduction GO:0035556 85 0.012
regulation of glucose import GO:0046324 1 0.012
positive regulation of dna metabolic process GO:0051054 1 0.012
regulation of cell migration GO:0030334 40 0.012
negative regulation of defense response GO:0031348 2 0.012
negative regulation of mapk cascade GO:0043409 4 0.012
regulation of oocyte development GO:0060281 3 0.012
outflow tract morphogenesis GO:0003151 1 0.012
single organism localization GO:1902578 225 0.012
regulation of protein polymerization GO:0032271 2 0.012
regulation of cell motility GO:2000145 46 0.012
protein targeting to nucleus GO:0044744 3 0.012
regulation of autophagy GO:0010506 3 0.012
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.012
cellular response to stress GO:0033554 62 0.012
regulation of protein transport GO:0051223 3 0.011
protein complex subunit organization GO:0071822 46 0.011
cell fate commitment GO:0045165 99 0.011
regulation of mitotic cell cycle GO:0007346 25 0.011
telomere organization GO:0032200 1 0.011
protein import GO:0017038 3 0.011
negative regulation of protein localization to nucleus GO:1900181 2 0.011
germ line stem cell maintenance GO:0030718 2 0.011
gland development GO:0048732 143 0.011
ameboidal type cell migration GO:0001667 143 0.011
response to nutrient GO:0007584 3 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.011
positive regulation of cell cycle GO:0045787 3 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
immunoglobulin production GO:0002377 1 0.011
hemopoiesis GO:0030097 183 0.011
oogenesis GO:0048477 14 0.011
actin filament based movement GO:0030048 1 0.011
neuroblast proliferation GO:0007405 2 0.011
regulation of cellular protein metabolic process GO:0032268 52 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
intracellular mrna localization GO:0008298 1 0.010
system process GO:0003008 185 0.010
internal peptidyl lysine acetylation GO:0018393 2 0.010
phosphorylation GO:0016310 69 0.010
macromolecule modification GO:0043412 111 0.010
rna localization GO:0006403 4 0.010
secondary metabolic process GO:0019748 3 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.010
myeloid cell development GO:0061515 32 0.010
sexual reproduction GO:0019953 36 0.010
positive regulation of stem cell proliferation GO:2000648 1 0.010
neuron projection guidance GO:0097485 86 0.010
positive regulation of multicellular organismal process GO:0051240 52 0.010
macromolecule localization GO:0033036 54 0.010

phactr4b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.049
nervous system disease DOID:863 0 0.019
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.011
musculoskeletal system disease DOID:17 0 0.011