Danio rerio

0 known processes

phc2

polyhomeotic-like 2 (Drosophila)

(Aliases: ph2[a],ph2beta,zgc:100775,cb218,ph2[b],wu:fb98c05,id:ibd2745,id:ibd5044,phc2a,wu:fc96f07,zgc:123102,ph2,ph2alpha,edr2,MGC123102)

phc2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
hematopoietic or lymphoid organ development GO:0048534 191 0.293
digestive tract morphogenesis GO:0048546 231 0.286
signal transduction GO:0007165 455 0.269
immune system process GO:0002376 241 0.228
neuron differentiation GO:0030182 353 0.216
Fly
regionalization GO:0003002 274 0.210
neuron projection development GO:0031175 180 0.196
regulation of metabolic process GO:0019222 359 0.191
Fly
cell fate commitment GO:0045165 99 0.165
cell fate specification GO:0001708 68 0.153
regulation of stem cell proliferation GO:0072091 2 0.150
tube morphogenesis GO:0035239 349 0.149
immune system development GO:0002520 191 0.146
stem cell division GO:0017145 1 0.143
regulation of nucleocytoplasmic transport GO:0046822 2 0.141
digestive system development GO:0055123 289 0.140
muscle cell differentiation GO:0042692 139 0.139
anterior posterior pattern specification GO:0009952 152 0.138
neuroblast proliferation GO:0007405 2 0.134
central nervous system development GO:0007417 387 0.133
Fly
cell migration GO:0016477 237 0.130
cellular component morphogenesis GO:0032989 336 0.129
Fly
retina morphogenesis in camera type eye GO:0060042 79 0.122
cellular component movement GO:0006928 335 0.117
regulation of multicellular organismal process GO:0051239 277 0.117
wnt signaling pathway GO:0016055 80 0.115
regulation of response to stimulus GO:0048583 269 0.112
regulation of signal transduction GO:0009966 225 0.112
negative regulation of biological process GO:0048519 304 0.110
Fly
nucleocytoplasmic transport GO:0006913 4 0.109
regulation of signaling GO:0023051 235 0.103
regulation of cytoplasmic transport GO:1903649 4 0.102
gastrulation GO:0007369 208 0.102
macromolecule biosynthetic process GO:0009059 227 0.100
Fly
rna biosynthetic process GO:0032774 181 0.099
Fly
brain development GO:0007420 293 0.097
sensory organ development GO:0007423 393 0.095
nuclear transport GO:0051169 4 0.095
positive regulation of transport GO:0051050 2 0.092
larval development GO:0002164 2 0.092
generation of neurons GO:0048699 385 0.090
Fly
mesoderm morphogenesis GO:0048332 51 0.090
cell morphogenesis GO:0000902 289 0.089
Fly
ameboidal type cell migration GO:0001667 143 0.088
cell projection organization GO:0030030 284 0.088
regulation of sequestering of calcium ion GO:0051282 4 0.087
formation of primary germ layer GO:0001704 62 0.087
regulation of establishment of protein localization GO:0070201 4 0.086
somitogenesis GO:0001756 87 0.086
macromolecule modification GO:0043412 111 0.086
cellular protein metabolic process GO:0044267 129 0.084
regulation of embryonic development GO:0045995 47 0.084
regulation of intracellular protein transport GO:0033157 3 0.084
somite development GO:0061053 96 0.078
cellular component assembly GO:0022607 170 0.077
regulation of wnt signaling pathway GO:0030111 53 0.077
protein metabolic process GO:0019538 183 0.076
regulation of nitrogen compound metabolic process GO:0051171 251 0.075
Fly
regulation of protein transport GO:0051223 3 0.074
cellular nitrogen compound metabolic process GO:0034641 290 0.073
Fly
single organism nuclear import GO:1902593 3 0.073
segmentation GO:0035282 97 0.072
cellular protein modification process GO:0006464 100 0.072
chemotaxis GO:0006935 104 0.071
cell surface receptor signaling pathway GO:0007166 325 0.070
camera type eye development GO:0043010 222 0.069
neuron projection guidance GO:0097485 86 0.069
neuron development GO:0048666 262 0.068
Fly
axonogenesis GO:0007409 152 0.068
negative regulation of synapse assembly GO:0051964 2 0.068
cell projection morphogenesis GO:0048858 244 0.068
chordate embryonic development GO:0043009 271 0.068
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.067
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.067
morphogenesis of an epithelium GO:0002009 333 0.066
Fly
somatic stem cell maintenance GO:0035019 1 0.065
muscle organ development GO:0007517 101 0.061
neural tube patterning GO:0021532 33 0.061
amine metabolic process GO:0009308 2 0.060
nitrogen compound metabolic process GO:0006807 319 0.060
Fly
regulation of cellular metabolic process GO:0031323 320 0.060
Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.060
sensory organ morphogenesis GO:0090596 200 0.058
protein modification process GO:0036211 100 0.058
positive regulation of cellular metabolic process GO:0031325 94 0.058
embryonic heart tube development GO:0035050 133 0.057
digestive tract development GO:0048565 265 0.057
establishment of protein localization to organelle GO:0072594 4 0.057
nuclear import GO:0051170 3 0.056
regulation of macromolecule biosynthetic process GO:0010556 225 0.055
Fly
regulation of rna metabolic process GO:0051252 224 0.054
Fly
oxoacid metabolic process GO:0043436 31 0.053
eye development GO:0001654 277 0.053
negative regulation of cellular process GO:0048523 283 0.053
Fly
locomotion GO:0040011 313 0.052
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.052
stem cell proliferation GO:0072089 4 0.052
embryonic organ development GO:0048568 381 0.052
regulation of synapse organization GO:0050807 3 0.051
head development GO:0060322 303 0.050
cell projection assembly GO:0030031 64 0.050
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.049
Fly
regulation of protein import into nucleus GO:0042306 2 0.049
regulation of protein targeting GO:1903533 2 0.048
small molecule metabolic process GO:0044281 77 0.047
cell motility GO:0048870 244 0.047
heart development GO:0007507 313 0.046
regulation of cellular amine metabolic process GO:0033238 0 0.045
negative regulation of protein phosphorylation GO:0001933 4 0.045
nucleobase containing compound metabolic process GO:0006139 274 0.045
Fly
cell part morphogenesis GO:0032990 246 0.044
neuron projection morphogenesis GO:0048812 161 0.044
organonitrogen compound metabolic process GO:1901564 74 0.043
taxis GO:0042330 109 0.043
axon development GO:0061564 166 0.043
establishment of localization GO:0051234 244 0.043
spinal cord development GO:0021510 46 0.043
retina development in camera type eye GO:0060041 146 0.043
cortical cytoskeleton organization GO:0030865 1 0.042
regulation of cell projection assembly GO:0060491 4 0.042
protein import GO:0017038 3 0.042
regulation of primary metabolic process GO:0080090 311 0.042
Fly
actin filament based process GO:0030029 64 0.041
hemopoiesis GO:0030097 183 0.041
regulation of cell fate specification GO:0042659 20 0.041
axon guidance GO:0007411 86 0.040
determination of bilateral symmetry GO:0009855 204 0.040
regulation of protein binding GO:0043393 3 0.039
regulation of anatomical structure morphogenesis GO:0022603 130 0.039
translational initiation GO:0006413 3 0.039
regulation of cellular amino acid metabolic process GO:0006521 0 0.039
cellular ketone metabolic process GO:0042180 11 0.038
carboxylic acid metabolic process GO:0019752 22 0.038
dorsal ventral pattern formation GO:0009953 125 0.038
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.038
nucleic acid metabolic process GO:0090304 244 0.038
Fly
lateral inhibition GO:0046331 1 0.038
positive regulation of cellular component biogenesis GO:0044089 3 0.037
regulation of catenin import into nucleus GO:0035412 2 0.037
lymph vessel development GO:0001945 27 0.037
cellular amino acid metabolic process GO:0006520 7 0.037
regulation of gene expression GO:0010468 265 0.036
Fly
protein localization to nucleus GO:0034504 3 0.036
protein targeting to nucleus GO:0044744 3 0.036
neural tube development GO:0021915 62 0.036
single organism organelle organization GO:1902589 199 0.035
negative regulation of transcription dna templated GO:0045892 45 0.035
Fly
canonical wnt signaling pathway GO:0060070 48 0.035
positive regulation of biological process GO:0048518 253 0.035
muscle structure development GO:0061061 196 0.035
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.035
multicellular organism growth GO:0035264 4 0.035
negative regulation of rna metabolic process GO:0051253 48 0.035
Fly
negative regulation of signaling GO:0023057 96 0.034
sequestering of calcium ion GO:0051208 3 0.034
intracellular transport GO:0046907 32 0.034
cellular response to endogenous stimulus GO:0071495 68 0.033
regulation of mrna processing GO:0050684 3 0.033
establishment of localization in cell GO:0051649 77 0.033
angiogenesis GO:0001525 158 0.033
peptidyl serine modification GO:0018209 2 0.032
regulation of cell communication GO:0010646 232 0.032
cognition GO:0050890 1 0.032
organic cyclic compound biosynthetic process GO:1901362 223 0.032
Fly
regulation of binding GO:0051098 3 0.032
cell cycle g1 s phase transition GO:0044843 1 0.032
negative regulation of sequestering of calcium ion GO:0051283 4 0.032
organic cyclic compound metabolic process GO:1901360 301 0.032
Fly
regulation of purine nucleotide catabolic process GO:0033121 2 0.032
regulation of translational initiation GO:0006446 1 0.031
regulation of apoptotic process GO:0042981 98 0.031
cell morphogenesis involved in differentiation GO:0000904 195 0.031
Fly
localization of cell GO:0051674 244 0.031
blood vessel development GO:0001568 246 0.031
positive regulation of cellular process GO:0048522 201 0.031
meiotic nuclear division GO:0007126 4 0.031
regulation of developmental process GO:0050793 247 0.030
embryonic limb morphogenesis GO:0030326 2 0.030
connective tissue development GO:0061448 99 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.030
regulation of cell fate commitment GO:0010453 22 0.030
negative regulation of cell communication GO:0010648 96 0.029
regulation of cell differentiation GO:0045595 142 0.029
maintenance of location GO:0051235 4 0.029
response to hexose GO:0009746 3 0.029
response to glucocorticoid GO:0051384 1 0.029
negative regulation of multicellular organismal process GO:0051241 69 0.029
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.028
response to carbohydrate GO:0009743 3 0.028
heart morphogenesis GO:0003007 156 0.028
cellular amine metabolic process GO:0044106 2 0.027
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.027
response to biotic stimulus GO:0009607 97 0.027
regulation of multicellular organismal development GO:2000026 223 0.027
biosynthetic process GO:0009058 294 0.027
Fly
specification of symmetry GO:0009799 204 0.027
enzyme linked receptor protein signaling pathway GO:0007167 106 0.027
peptidyl lysine acetylation GO:0018394 2 0.027
spindle assembly GO:0051225 2 0.027
muscle cell development GO:0055001 115 0.026
positive regulation of signaling GO:0023056 56 0.026
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.026
muscle tissue development GO:0060537 110 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.026
positive regulation of leukocyte differentiation GO:1902107 1 0.026
female meiotic division GO:0007143 2 0.026
regulation of stem cell differentiation GO:2000736 4 0.026
protein import into nucleus GO:0006606 3 0.026
regulation of protein localization to nucleus GO:1900180 2 0.026
mesoderm development GO:0007498 88 0.025
rna metabolic process GO:0016070 219 0.025
Fly
posterior lateral line system development GO:0048915 46 0.025
cellular aromatic compound metabolic process GO:0006725 295 0.025
Fly
hindbrain development GO:0030902 91 0.024
negative regulation of gene expression GO:0010629 65 0.024
Fly
regulation of biosynthetic process GO:0009889 250 0.024
Fly
negative regulation of cellular biosynthetic process GO:0031327 55 0.024
Fly
response to corticosteroid GO:0031960 1 0.024
multi organism process GO:0051704 134 0.024
Mouse Fly
intracellular signal transduction GO:0035556 85 0.024
regulation of synapse assembly GO:0051963 3 0.024
cytoskeleton organization GO:0007010 96 0.023
fin development GO:0033333 77 0.023
positive regulation of cytokine production GO:0001819 2 0.023
stem cell maintenance GO:0019827 4 0.023
response to external stimulus GO:0009605 264 0.023
regulation of cytokine production GO:0001817 3 0.023
vasculature development GO:0001944 278 0.023
negative regulation of macromolecule metabolic process GO:0010605 76 0.022
Fly
negative regulation of intracellular signal transduction GO:1902532 22 0.022
response to chemical GO:0042221 320 0.022
Fly
cellular response to decreased oxygen levels GO:0036294 1 0.022
gastrulation with mouth forming second GO:0001702 44 0.022
regulation of intracellular signal transduction GO:1902531 57 0.022
cellular response to oxygen levels GO:0071453 1 0.022
system process GO:0003008 185 0.022
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.022
embryonic hemopoiesis GO:0035162 53 0.022
myeloid cell differentiation GO:0030099 86 0.022
regulation of cellular ketone metabolic process GO:0010565 7 0.021
regulation of cell shape GO:0008360 1 0.021
macromolecular complex subunit organization GO:0043933 74 0.021
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.021
negative regulation of cellular metabolic process GO:0031324 77 0.021
Fly
regulation of canonical wnt signaling pathway GO:0060828 34 0.021
negative regulation of signal transduction GO:0009968 94 0.021
negative regulation of wnt signaling pathway GO:0030178 30 0.021
regulation of protein ubiquitination GO:0031396 3 0.021
negative regulation of protein kinase activity GO:0006469 4 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.021
Fly
appendage development GO:0048736 80 0.020
meiotic spindle organization GO:0000212 1 0.020
cellular component disassembly GO:0022411 1 0.020
neuroblast differentiation GO:0014016 1 0.020
b cell activation GO:0042113 2 0.020
phagocytosis GO:0006909 3 0.020
ubiquitin dependent protein catabolic process GO:0006511 3 0.020
cytokinesis GO:0000910 3 0.020
regulation of macromolecule metabolic process GO:0060255 317 0.020
Fly
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.020
positive regulation of cell cycle GO:0045787 3 0.020
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.020
cell migration involved in gastrulation GO:0042074 79 0.020
meiotic cell cycle process GO:1903046 3 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
Fly
positive regulation of immune effector process GO:0002699 3 0.020
reactive oxygen species biosynthetic process GO:1903409 1 0.020
modification dependent macromolecule catabolic process GO:0043632 3 0.019
positive regulation of protein complex assembly GO:0031334 2 0.019
regulation of localization GO:0032879 104 0.019
regulation of nucleoside metabolic process GO:0009118 2 0.019
heart looping GO:0001947 94 0.019
protein complex biogenesis GO:0070271 30 0.019
positive regulation of nucleoside metabolic process GO:0045979 1 0.019
spermatid differentiation GO:0048515 2 0.019
apoptotic process GO:0006915 116 0.019
single organism metabolic process GO:0044710 217 0.019
transcription from rna polymerase ii promoter GO:0006366 80 0.019
organic acid metabolic process GO:0006082 31 0.019
sulfur compound metabolic process GO:0006790 13 0.019
single organism localization GO:1902578 225 0.019
negative regulation of apoptotic process GO:0043066 55 0.019
actin cytoskeleton organization GO:0030036 63 0.019
single organism transport GO:0044765 206 0.019
inner ear receptor cell fate commitment GO:0060120 4 0.018
modification dependent protein catabolic process GO:0019941 3 0.018
mesoderm formation GO:0001707 43 0.018
regulation of multicellular organism growth GO:0040014 4 0.018
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.018
regulation of cell development GO:0060284 100 0.018
eye morphogenesis GO:0048592 144 0.018
synaptic growth at neuromuscular junction GO:0051124 2 0.018
positive regulation of cellular catabolic process GO:0031331 3 0.018
skeletal system development GO:0001501 181 0.018
proteasomal protein catabolic process GO:0010498 2 0.018
heterocycle biosynthetic process GO:0018130 215 0.018
Fly
myeloid cell development GO:0061515 32 0.018
cellular protein catabolic process GO:0044257 4 0.018
posterior lateral line neuromast development GO:0048919 20 0.018
tissue migration GO:0090130 37 0.018
regulation of gastrulation GO:0010470 24 0.017
regulation of reproductive process GO:2000241 4 0.017
cellular biosynthetic process GO:0044249 286 0.017
Fly
gene expression GO:0010467 252 0.017
Fly
i kappab kinase nf kappab signaling GO:0007249 4 0.017
multi organism cellular process GO:0044764 2 0.017
male meiosis GO:0007140 2 0.017
phosphate containing compound metabolic process GO:0006796 108 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
organelle organization GO:0006996 227 0.017
cellular localization GO:0051641 97 0.017
regulation of protein complex assembly GO:0043254 3 0.017
positive regulation of map kinase activity GO:0043406 3 0.017
negative regulation of cell death GO:0060548 60 0.017
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.017
myeloid cell homeostasis GO:0002262 56 0.017
positive regulation of nucleotide catabolic process GO:0030813 1 0.017
negative regulation of rna biosynthetic process GO:1902679 45 0.017
Fly
chemosensory behavior GO:0007635 1 0.017
negative regulation of intracellular transport GO:0032387 3 0.016
regulation of neural precursor cell proliferation GO:2000177 3 0.016
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.016
regulation of rna biosynthetic process GO:2001141 213 0.016
Fly
striated muscle cell development GO:0055002 108 0.016
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.016
response to monosaccharide GO:0034284 3 0.016
phosphorus metabolic process GO:0006793 109 0.016
segment specification GO:0007379 12 0.016
cell cell signaling GO:0007267 52 0.016
positive regulation of catabolic process GO:0009896 4 0.016
cortical actin cytoskeleton organization GO:0030866 1 0.016
cell cycle GO:0007049 93 0.016
Fly
spermatid development GO:0007286 2 0.016
aging GO:0007568 2 0.016
protein complex localization GO:0031503 1 0.016
diencephalon development GO:0021536 58 0.016
programmed cell death GO:0012501 119 0.016
olfactory bulb development GO:0021772 4 0.016
convergent extension GO:0060026 118 0.016
response to lipid GO:0033993 60 0.016
Fly
sensory system development GO:0048880 76 0.016
positive regulation of dna metabolic process GO:0051054 1 0.016
regulation of cell cell adhesion GO:0022407 13 0.016
spindle assembly involved in meiosis GO:0090306 1 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.016
negative regulation of response to stimulus GO:0048585 104 0.016
positive regulation of response to stimulus GO:0048584 80 0.015
cell proliferation GO:0008283 80 0.015
axis specification GO:0009798 43 0.015
nuclear migration GO:0007097 3 0.015
establishment of blood brain barrier GO:0060856 2 0.015
regulation of production of molecular mediator of immune response GO:0002700 1 0.015
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.015
nuclear export GO:0051168 1 0.015
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060823 4 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.015
Fly
regulation of protein catabolic process GO:0042176 1 0.015
adult behavior GO:0030534 2 0.015
positive regulation of cell activation GO:0050867 1 0.015
negative regulation of ras protein signal transduction GO:0046580 1 0.015
response to drug GO:0042493 3 0.015
cellular response to external stimulus GO:0071496 2 0.015
negative regulation of kinase activity GO:0033673 4 0.015
fin morphogenesis GO:0033334 53 0.015
regulation of molecular function GO:0065009 70 0.015
regulation of catalytic activity GO:0050790 55 0.015
apical junction assembly GO:0043297 1 0.015
cellular macromolecule metabolic process GO:0044260 391 0.015
Fly
regulation of reactive oxygen species metabolic process GO:2000377 2 0.014
g1 s transition of mitotic cell cycle GO:0000082 1 0.014
positive regulation of multi organism process GO:0043902 3 0.014
calcium ion transport into cytosol GO:0060402 3 0.014
positive regulation of cellular protein metabolic process GO:0032270 22 0.014
muscle fiber development GO:0048747 52 0.014
alpha amino acid metabolic process GO:1901605 3 0.014
skeletal system morphogenesis GO:0048705 102 0.014
transport GO:0006810 220 0.014
regulation of skeletal muscle tissue development GO:0048641 4 0.014
cellular nitrogen compound biosynthetic process GO:0044271 218 0.014
Fly
regulation of anatomical structure size GO:0090066 33 0.014
response to abiotic stimulus GO:0009628 122 0.014
heterocycle metabolic process GO:0046483 290 0.014
Fly
auditory receptor cell fate commitment GO:0009912 4 0.014
multicellular organism reproduction GO:0032504 35 0.014
Mouse Fly
mitotic cell cycle GO:0000278 64 0.014
Fly
blood vessel morphogenesis GO:0048514 216 0.013
internal peptidyl lysine acetylation GO:0018393 2 0.013
death GO:0016265 121 0.013
digestive tract mesoderm development GO:0007502 1 0.013
regulation of cell activation GO:0050865 1 0.013
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.013
positive regulation of biosynthetic process GO:0009891 68 0.013
regulation of metal ion transport GO:0010959 4 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.013
catenin import into nucleus GO:0035411 2 0.013
cilium morphogenesis GO:0060271 85 0.013
positive regulation of signal transduction GO:0009967 56 0.013
nucleobase containing compound biosynthetic process GO:0034654 205 0.013
Fly
regulation of cellular component movement GO:0051270 55 0.013
aorta development GO:0035904 4 0.013
developmental growth involved in morphogenesis GO:0060560 86 0.013
skeletal muscle organ development GO:0060538 78 0.013
regulation of jak stat cascade GO:0046425 3 0.013
regulation of mrna splicing via spliceosome GO:0048024 3 0.013
cellular response to dna damage stimulus GO:0006974 24 0.013
regulation of filopodium assembly GO:0051489 2 0.013
regulation of cell morphogenesis GO:0022604 42 0.013
epidermal cell differentiation GO:0009913 36 0.013
pectoral fin development GO:0033339 50 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
endodermal cell fate specification GO:0001714 17 0.013
skeletal muscle fiber development GO:0048741 35 0.013
rna localization GO:0006403 4 0.013
g2 m transition of mitotic cell cycle GO:0000086 4 0.013
actomyosin structure organization GO:0031032 53 0.013
cellular response to hypoxia GO:0071456 1 0.012
positive regulation of production of molecular mediator of immune response GO:0002702 1 0.012
axonal fasciculation GO:0007413 11 0.012
negative regulation of protein localization to nucleus GO:1900181 2 0.012
organic substance transport GO:0071702 58 0.012
forebrain neuron fate commitment GO:0021877 1 0.012
response to external biotic stimulus GO:0043207 97 0.012
homeostatic process GO:0042592 142 0.012
proximal distal pattern formation GO:0009954 1 0.012
regulation of phosphorus metabolic process GO:0051174 43 0.012
negative regulation of stem cell differentiation GO:2000737 2 0.012
regulation of skeletal muscle fiber development GO:0048742 2 0.012
embryonic organ morphogenesis GO:0048562 274 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.012
tissue remodeling GO:0048771 4 0.012
glial cell migration GO:0008347 3 0.012
peripheral nervous system development GO:0007422 55 0.012
leukocyte proliferation GO:0070661 1 0.012
protein complex assembly GO:0006461 30 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.012
response to growth factor GO:0070848 39 0.012
primitive hemopoiesis GO:0060215 27 0.012
camera type eye morphogenesis GO:0048593 108 0.012
endocardial cushion formation GO:0003272 2 0.012
olfactory lobe development GO:0021988 4 0.012
nephron epithelium morphogenesis GO:0072088 1 0.012
sequestering of metal ion GO:0051238 3 0.012
positive regulation of secretion GO:0051047 1 0.012
cellular response to radiation GO:0071478 4 0.012
positive regulation of cell communication GO:0010647 56 0.012
positive regulation of cell differentiation GO:0045597 30 0.012
lymphangiogenesis GO:0001946 25 0.012
transcription dna templated GO:0006351 181 0.012
Fly
negative regulation of protein complex assembly GO:0031333 1 0.012
cell death GO:0008219 121 0.012
artery development GO:0060840 22 0.012
neuromuscular synaptic transmission GO:0007274 2 0.012
cardiocyte differentiation GO:0035051 44 0.012
convergent extension involved in organogenesis GO:0060029 10 0.011
regulation of inflammatory response GO:0050727 2 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
epithelial cell development GO:0002064 42 0.011
Fly
regulation of cardiac muscle tissue development GO:0055024 1 0.011
cellular component biogenesis GO:0044085 178 0.011
appendage morphogenesis GO:0035107 56 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
Fly
neuroblast fate commitment GO:0014017 1 0.011
determination of heart left right asymmetry GO:0061371 117 0.011
regulation of epithelial to mesenchymal transition GO:0010717 3 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
rna transport GO:0050658 2 0.011
determination of left right symmetry GO:0007368 179 0.011
regulation of myotube differentiation GO:0010830 2 0.011
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.011
developmental growth GO:0048589 166 0.011
regulation of receptor mediated endocytosis GO:0048259 4 0.011
cilium assembly GO:0042384 58 0.011
signal transduction in absence of ligand GO:0038034 1 0.011
nucleic acid templated transcription GO:0097659 181 0.011
Fly
cell migration involved in heart development GO:0060973 22 0.011
cellular macromolecule biosynthetic process GO:0034645 224 0.011
Fly
embryonic pattern specification GO:0009880 44 0.011
positive regulation of metabolic process GO:0009893 108 0.011
neuron recognition GO:0008038 18 0.011
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 2 0.011
ectodermal placode development GO:0071696 37 0.011
startle response GO:0001964 4 0.011
keratinocyte differentiation GO:0030216 0 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
optic placode formation GO:0001743 4 0.011
cytosolic calcium ion transport GO:0060401 3 0.011
striated muscle cell differentiation GO:0051146 129 0.011
epithelium migration GO:0090132 25 0.010
regulation of locomotion GO:0040012 55 0.010
osteoclast differentiation GO:0030316 1 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.010
Fly
regulation of developmental growth GO:0048638 38 0.010
organelle localization GO:0051640 49 0.010

phc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.049
nervous system disease DOID:863 0 0.032
disease of cellular proliferation DOID:14566 0 0.011
musculoskeletal system disease DOID:17 0 0.011
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011