Danio rerio

0 known processes

phex

phosphate regulating gene with homologues to endopeptidases on the X chromosome

(Aliases: wu:fx03e08)

phex biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
glucose import GO:0046323 2 0.362
central nervous system development GO:0007417 387 0.210
gland development GO:0048732 143 0.149
mesoderm development GO:0007498 88 0.141
larval development GO:0002164 2 0.140
regulation of glucose import GO:0046324 1 0.119
aging GO:0007568 2 0.114
regulation of glucose transport GO:0010827 1 0.100
neuroblast proliferation GO:0007405 2 0.099
nucleic acid templated transcription GO:0097659 181 0.094
positive regulation of transport GO:0051050 2 0.093
camera type eye morphogenesis GO:0048593 108 0.091
stem cell proliferation GO:0072089 4 0.086
positive regulation of glucose transport GO:0010828 1 0.083
muscle cell differentiation GO:0042692 139 0.080
response to carbohydrate GO:0009743 3 0.079
single organism transport GO:0044765 206 0.074
hepaticobiliary system development GO:0061008 98 0.071
single organism localization GO:1902578 225 0.069
nuclear migration GO:0007097 3 0.064
transport GO:0006810 220 0.063
cellular amine metabolic process GO:0044106 2 0.062
regulation of response to stimulus GO:0048583 269 0.061
embryonic organ development GO:0048568 381 0.059
cellular nitrogen compound biosynthetic process GO:0044271 218 0.059
single organism organelle organization GO:1902589 199 0.058
positive regulation of cellular component biogenesis GO:0044089 3 0.058
astrocyte differentiation GO:0048708 1 0.058
single organism metabolic process GO:0044710 217 0.058
single organism cellular localization GO:1902580 46 0.056
response to stress GO:0006950 263 0.055
response to biotic stimulus GO:0009607 97 0.054
tissue regeneration GO:0042246 74 0.054
cellular response to organic substance GO:0071310 105 0.052
response to wounding GO:0009611 116 0.052
cellular macromolecule biosynthetic process GO:0034645 224 0.052
camera type eye development GO:0043010 222 0.052
morphogenesis of an epithelium GO:0002009 333 0.051
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.051
organelle localization GO:0051640 49 0.049
leukocyte proliferation GO:0070661 1 0.049
regulation of stem cell differentiation GO:2000736 4 0.048
response to monosaccharide GO:0034284 3 0.048
liver development GO:0001889 96 0.048
regulation of biological quality GO:0065008 263 0.048
reactive nitrogen species metabolic process GO:2001057 0 0.048
response to chemical GO:0042221 320 0.045
regulation of cell activation GO:0050865 1 0.045
regulation of protein localization to nucleus GO:1900180 2 0.044
establishment of protein localization to organelle GO:0072594 4 0.044
catechol containing compound metabolic process GO:0009712 2 0.044
germ line stem cell division GO:0042078 1 0.043
muscle organ development GO:0007517 101 0.043
negative regulation of biological process GO:0048519 304 0.042
skeletal system development GO:0001501 181 0.042
cell fate commitment GO:0045165 99 0.041
response to hexose GO:0009746 3 0.041
negative regulation of cellular process GO:0048523 283 0.041
sensory organ development GO:0007423 393 0.041
tube morphogenesis GO:0035239 349 0.040
eye morphogenesis GO:0048592 144 0.040
medulla oblongata development GO:0021550 4 0.040
biosynthetic process GO:0009058 294 0.040
regulation of leukocyte mediated immunity GO:0002703 1 0.040
nuclear transport GO:0051169 4 0.040
blood vessel morphogenesis GO:0048514 216 0.040
positive regulation of catabolic process GO:0009896 4 0.040
positive regulation of glucose import GO:0046326 1 0.040
vasculature development GO:0001944 278 0.039
response to transition metal nanoparticle GO:1990267 28 0.039
guanosine containing compound metabolic process GO:1901068 4 0.039
protein localization to nucleus GO:0034504 3 0.039
positive regulation of map kinase activity GO:0043406 3 0.039
extrinsic apoptotic signaling pathway GO:0097191 3 0.039
mononuclear cell proliferation GO:0032943 1 0.038
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.037
transcription dna templated GO:0006351 181 0.037
kidney development GO:0001822 92 0.037
heterocycle biosynthetic process GO:0018130 215 0.036
regulation of production of molecular mediator of immune response GO:0002700 1 0.036
regulation of rna biosynthetic process GO:2001141 213 0.036
regulation of ph GO:0006885 3 0.036
stem cell division GO:0017145 1 0.036
regulation of cytokine production GO:0001817 3 0.036
homeostatic process GO:0042592 142 0.036
type b pancreatic cell development GO:0003323 4 0.036
urogenital system development GO:0001655 97 0.036
cellular nitrogen compound metabolic process GO:0034641 290 0.035
multi organism cellular process GO:0044764 2 0.035
amine metabolic process GO:0009308 2 0.035
negative regulation of secretion by cell GO:1903531 2 0.035
regulation of signaling GO:0023051 235 0.034
organonitrogen compound metabolic process GO:1901564 74 0.034
cellular response to estrogen stimulus GO:0071391 24 0.033
production of molecular mediator of immune response GO:0002440 2 0.033
organic acid metabolic process GO:0006082 31 0.033
gtp catabolic process GO:0006184 2 0.033
hemopoiesis GO:0030097 183 0.033
myeloid leukocyte mediated immunity GO:0002444 1 0.033
cell projection organization GO:0030030 284 0.033
organelle organization GO:0006996 227 0.032
synaptic growth at neuromuscular junction GO:0051124 2 0.032
embryo development ending in birth or egg hatching GO:0009792 271 0.032
regulation of phospholipase c activity GO:1900274 1 0.031
phosphate containing compound metabolic process GO:0006796 108 0.031
regulation of multicellular organism growth GO:0040014 4 0.031
response to nutrient GO:0007584 3 0.031
positive regulation of lipase activity GO:0060193 1 0.031
organic substance biosynthetic process GO:1901576 289 0.031
modulation by virus of host morphology or physiology GO:0019048 1 0.031
regulation of autophagy GO:0010506 3 0.030
viral process GO:0016032 1 0.030
regulation of cellular amine metabolic process GO:0033238 0 0.030
nucleocytoplasmic transport GO:0006913 4 0.029
adherens junction organization GO:0034332 4 0.029
regulation of cell differentiation GO:0045595 142 0.029
monovalent inorganic cation transport GO:0015672 42 0.029
nucleobase containing compound biosynthetic process GO:0034654 205 0.029
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.028
multi organism process GO:0051704 134 0.028
ameboidal type cell migration GO:0001667 143 0.028
embryonic organ morphogenesis GO:0048562 274 0.028
lymphocyte proliferation GO:0046651 1 0.028
positive regulation of gliogenesis GO:0014015 2 0.027
negative regulation of protein phosphorylation GO:0001933 4 0.027
axonogenesis GO:0007409 152 0.027
organic cyclic compound biosynthetic process GO:1901362 223 0.027
chordate embryonic development GO:0043009 271 0.027
protein localization to plasma membrane GO:0072659 1 0.027
spinal cord development GO:0021510 46 0.027
muscle structure development GO:0061061 196 0.027
cellular localization GO:0051641 97 0.027
regulation of anatomical structure morphogenesis GO:0022603 130 0.027
cellular carbohydrate metabolic process GO:0044262 4 0.027
neural tube development GO:0021915 62 0.027
regulation of synapse organization GO:0050807 3 0.027
protein localization GO:0008104 40 0.026
nuclear import GO:0051170 3 0.026
primary amino compound biosynthetic process GO:1901162 1 0.026
anatomical structure homeostasis GO:0060249 36 0.026
regulation of cell death GO:0010941 103 0.026
male meiosis GO:0007140 2 0.026
regulation of multicellular organismal process GO:0051239 277 0.026
gtp metabolic process GO:0046039 4 0.025
mitochondrion organization GO:0007005 4 0.025
positive regulation of biological process GO:0048518 253 0.025
cell proliferation GO:0008283 80 0.025
protein complex assembly GO:0006461 30 0.025
rna metabolic process GO:0016070 219 0.025
establishment of localization GO:0051234 244 0.025
cell cycle GO:0007049 93 0.025
hematopoietic or lymphoid organ development GO:0048534 191 0.025
nitrogen compound metabolic process GO:0006807 319 0.025
regulation of cell communication GO:0010646 232 0.025
negative regulation of intracellular transport GO:0032387 3 0.025
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.025
generation of neurons GO:0048699 385 0.024
cellular macromolecule metabolic process GO:0044260 391 0.024
regulation of canonical wnt signaling pathway GO:0060828 34 0.024
tissue remodeling GO:0048771 4 0.024
positive regulation of cell activation GO:0050867 1 0.024
maintenance of location GO:0051235 4 0.024
b cell mediated immunity GO:0019724 3 0.024
embryonic pattern specification GO:0009880 44 0.024
regulation of nitrogen compound metabolic process GO:0051171 251 0.024
regulation of macromolecule biosynthetic process GO:0010556 225 0.023
endothelial cell development GO:0001885 12 0.023
cell migration GO:0016477 237 0.023
wnt signaling pathway GO:0016055 80 0.023
macromolecular complex subunit organization GO:0043933 74 0.023
exocytosis GO:0006887 1 0.023
positive regulation of immune effector process GO:0002699 3 0.023
one carbon compound transport GO:0019755 14 0.023
response to organic cyclic compound GO:0014070 51 0.023
energy reserve metabolic process GO:0006112 2 0.022
determination of bilateral symmetry GO:0009855 204 0.022
regulation of establishment of protein localization GO:0070201 4 0.022
muscle fiber development GO:0048747 52 0.022
phagocytosis GO:0006909 3 0.022
response to glucose GO:0009749 3 0.022
brain development GO:0007420 293 0.022
establishment of spindle orientation GO:0051294 10 0.022
chemical homeostasis GO:0048878 49 0.022
renal system development GO:0072001 94 0.022
catechol containing compound biosynthetic process GO:0009713 2 0.021
autophagy GO:0006914 4 0.021
signal transduction GO:0007165 455 0.021
gene expression GO:0010467 252 0.021
positive regulation of cell communication GO:0010647 56 0.021
response to endogenous stimulus GO:0009719 83 0.021
immunoglobulin mediated immune response GO:0016064 3 0.021
catecholamine biosynthetic process GO:0042423 2 0.021
positive regulation of cellular catabolic process GO:0031331 3 0.021
immune system process GO:0002376 241 0.021
intracellular transport GO:0046907 32 0.021
death GO:0016265 121 0.021
digestive tract development GO:0048565 265 0.021
digestive tract morphogenesis GO:0048546 231 0.021
eye development GO:0001654 277 0.021
cellular response to organic cyclic compound GO:0071407 38 0.021
circulatory system process GO:0003013 87 0.021
response to other organism GO:0051707 97 0.020
regulation of neural precursor cell proliferation GO:2000177 3 0.020
cellular response to extracellular stimulus GO:0031668 2 0.020
central nervous system neuron differentiation GO:0021953 74 0.020
guanosine containing compound catabolic process GO:1901069 2 0.020
response to estrogen GO:0043627 27 0.020
single organism nuclear import GO:1902593 3 0.020
positive regulation of jnk cascade GO:0046330 3 0.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.020
carboxylic acid metabolic process GO:0019752 22 0.019
developmental cell growth GO:0048588 52 0.019
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.019
regulation of reproductive process GO:2000241 4 0.019
negative regulation of immune response GO:0050777 2 0.019
blood circulation GO:0008015 87 0.019
establishment or maintenance of cell polarity GO:0007163 29 0.019
regulation of sodium ion transport GO:0002028 2 0.019
digestive tract mesoderm development GO:0007502 1 0.019
b cell activation GO:0042113 2 0.019
heterocycle metabolic process GO:0046483 290 0.019
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.019
female sex differentiation GO:0046660 4 0.019
cellular response to external stimulus GO:0071496 2 0.019
cellular component morphogenesis GO:0032989 336 0.019
cellular biosynthetic process GO:0044249 286 0.019
protein import GO:0017038 3 0.019
response to uv GO:0009411 3 0.018
developmental growth involved in morphogenesis GO:0060560 86 0.018
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.018
regulation of myotube differentiation GO:0010830 2 0.018
heart development GO:0007507 313 0.018
organelle assembly GO:0070925 110 0.018
interspecies interaction between organisms GO:0044419 4 0.018
striated muscle cell development GO:0055002 108 0.018
cellular response to decreased oxygen levels GO:0036294 1 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.018
negative regulation of cell communication GO:0010648 96 0.018
specification of symmetry GO:0009799 204 0.017
macromolecule modification GO:0043412 111 0.017
growth GO:0040007 174 0.017
regulation of binding GO:0051098 3 0.017
regeneration GO:0031099 91 0.017
myotube cell development GO:0014904 35 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
oxoacid metabolic process GO:0043436 31 0.017
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.017
internal protein amino acid acetylation GO:0006475 2 0.017
multicellular organism growth GO:0035264 4 0.017
hydrogen peroxide metabolic process GO:0042743 2 0.017
cellular response to chemical stimulus GO:0070887 157 0.017
macromolecule localization GO:0033036 54 0.016
regulation of immune system process GO:0002682 34 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
regulation of transmembrane transporter activity GO:0022898 2 0.016
cellular component biogenesis GO:0044085 178 0.016
regulation of carbohydrate metabolic process GO:0006109 4 0.016
regulation of immunoglobulin production GO:0002637 1 0.016
morphogenesis of an epithelial sheet GO:0002011 49 0.016
protein import into nucleus GO:0006606 3 0.016
cartilage condensation GO:0001502 3 0.016
negative regulation of ras protein signal transduction GO:0046580 1 0.016
cellular response to starvation GO:0009267 1 0.016
angiogenesis GO:0001525 158 0.016
regulation of stem cell proliferation GO:0072091 2 0.016
muscle tissue development GO:0060537 110 0.015
cortical cytoskeleton organization GO:0030865 1 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
activation of mapk activity GO:0000187 3 0.015
regulation of mrna catabolic process GO:0061013 3 0.015
nitric oxide metabolic process GO:0046209 2 0.015
apical protein localization GO:0045176 6 0.015
regulation of vasculature development GO:1901342 33 0.015
regulation of mrna processing GO:0050684 3 0.015
heart process GO:0003015 71 0.015
circadian sleep wake cycle GO:0042745 2 0.015
retina morphogenesis in camera type eye GO:0060042 79 0.015
striated muscle cell differentiation GO:0051146 129 0.015
embryonic retina morphogenesis in camera type eye GO:0060059 22 0.015
organic cyclic compound metabolic process GO:1901360 301 0.015
cell morphogenesis involved in differentiation GO:0000904 195 0.015
peptide transport GO:0015833 1 0.015
neuron projection guidance GO:0097485 86 0.015
epidermal cell differentiation GO:0009913 36 0.015
cellular component movement GO:0006928 335 0.015
behavior GO:0007610 74 0.015
cell morphogenesis GO:0000902 289 0.015
positive regulation of stress activated mapk cascade GO:0032874 3 0.015
spindle localization GO:0051653 12 0.015
ear development GO:0043583 127 0.015
regulation of mitochondrion organization GO:0010821 1 0.015
regulation of ion transmembrane transporter activity GO:0032412 2 0.015
small molecule metabolic process GO:0044281 77 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.014
establishment of localization in cell GO:0051649 77 0.014
adult behavior GO:0030534 2 0.014
skeletal system morphogenesis GO:0048705 102 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
connective tissue development GO:0061448 99 0.014
regulation of wnt signaling pathway GO:0030111 53 0.014
gastrulation GO:0007369 208 0.014
regulation of oocyte development GO:0060281 3 0.014
response to amine GO:0014075 1 0.014
negative regulation of response to stimulus GO:0048585 104 0.014
establishment of apical basal cell polarity GO:0035089 2 0.014
regulation of developmental process GO:0050793 247 0.014
endothelial cell migration GO:0043542 19 0.014
organic substance transport GO:0071702 58 0.014
skeletal muscle fiber development GO:0048741 35 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.014
melanin metabolic process GO:0006582 2 0.014
germ line stem cell maintenance GO:0030718 2 0.014
lipid metabolic process GO:0006629 52 0.014
superoxide metabolic process GO:0006801 2 0.013
cellular response to endogenous stimulus GO:0071495 68 0.013
regulation of signal transduction GO:0009966 225 0.013
negative regulation of secretion GO:0051048 2 0.013
regulation of jun kinase activity GO:0043506 3 0.013
immunoglobulin production GO:0002377 1 0.013
epithelial tube morphogenesis GO:0060562 148 0.013
cell projection morphogenesis GO:0048858 244 0.013
response to corticosteroid GO:0031960 1 0.013
regulation of reactive oxygen species metabolic process GO:2000377 2 0.013
developmental maturation GO:0021700 34 0.013
serotonin metabolic process GO:0042428 1 0.013
proteolysis GO:0006508 38 0.013
leukocyte mediated immunity GO:0002443 6 0.013
cation transport GO:0006812 81 0.013
biological adhesion GO:0022610 40 0.013
regulation of epithelial to mesenchymal transition GO:0010717 3 0.013
chemotaxis GO:0006935 104 0.013
regulation of skeletal muscle fiber development GO:0048742 2 0.012
positive regulation of cell death GO:0010942 29 0.012
regulation of biosynthetic process GO:0009889 250 0.012
glycerolipid biosynthetic process GO:0045017 1 0.012
programmed cell death GO:0012501 119 0.012
reactive oxygen species biosynthetic process GO:1903409 1 0.012
embryonic camera type eye development GO:0031076 29 0.012
stem cell maintenance GO:0019827 4 0.012
morphogenesis of embryonic epithelium GO:0016331 30 0.012
positive regulation of signal transduction GO:0009967 56 0.012
canonical wnt signaling pathway GO:0060070 48 0.012
regulation of growth rate GO:0040009 1 0.012
negative regulation of hormone secretion GO:0046888 2 0.012
epithelial cell differentiation GO:0030855 116 0.012
digestive system development GO:0055123 289 0.012
regulation of transporter activity GO:0032409 2 0.012
cortical actin cytoskeleton organization GO:0030866 1 0.012
retina development in camera type eye GO:0060041 146 0.012
dopamine biosynthetic process GO:0042416 2 0.012
epidermis development GO:0008544 48 0.012
neuron projection extension GO:1990138 45 0.012
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.012
determination of heart left right asymmetry GO:0061371 117 0.012
regulation of muscle contraction GO:0006937 3 0.012
response to growth factor GO:0070848 39 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
response to external biotic stimulus GO:0043207 97 0.012
protein acylation GO:0043543 3 0.012
response to abiotic stimulus GO:0009628 122 0.012
phosphorus metabolic process GO:0006793 109 0.012
female gonad development GO:0008585 4 0.012
carbohydrate derivative metabolic process GO:1901135 61 0.011
negative regulation of kinase activity GO:0033673 4 0.011
regulation of programmed cell death GO:0043067 101 0.011
axon extension GO:0048675 45 0.011
positive regulation of secretion by cell GO:1903532 1 0.011
response to vitamin GO:0033273 3 0.011
ubiquitin dependent protein catabolic process GO:0006511 3 0.011
positive regulation of positive chemotaxis GO:0050927 4 0.011
cellular protein modification process GO:0006464 100 0.011
regulation of primary metabolic process GO:0080090 311 0.011
cell death GO:0008219 121 0.011
dopamine metabolic process GO:0042417 2 0.011
positive regulation of jun kinase activity GO:0043507 2 0.011
embryonic hemopoiesis GO:0035162 53 0.011
negative regulation of signal transduction GO:0009968 94 0.011
sodium ion transport GO:0006814 24 0.011
developmental growth GO:0048589 166 0.011
cellular response to oxygen levels GO:0071453 1 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
internal peptidyl lysine acetylation GO:0018393 2 0.011
regulation of tube size GO:0035150 2 0.011
regulation of cellular biosynthetic process GO:0031326 245 0.011
endoderm development GO:0007492 49 0.011
protein targeting to nucleus GO:0044744 3 0.011
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 10 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
regulation of cellular component movement GO:0051270 55 0.011
rna biosynthetic process GO:0032774 181 0.011
single organism biosynthetic process GO:0044711 71 0.011
oocyte maturation GO:0001556 4 0.011
cell motility GO:0048870 244 0.011
response to glucocorticoid GO:0051384 1 0.011
cell maturation GO:0048469 23 0.011
response to ketone GO:1901654 1 0.011
regulation of exocytosis GO:0017157 1 0.011
neuron projection morphogenesis GO:0048812 161 0.011
membrane fusion GO:0061025 2 0.011
wound healing GO:0042060 90 0.011
negative regulation of cytokine production GO:0001818 1 0.011
response to estradiol GO:0032355 6 0.011
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.011
axon guidance GO:0007411 86 0.011
regulation of metal ion transport GO:0010959 4 0.011
cognition GO:0050890 1 0.011
regulation of circadian rhythm GO:0042752 4 0.011
determination of ventral identity GO:0048264 21 0.010
carbohydrate biosynthetic process GO:0016051 1 0.010
regulation of cellular component size GO:0032535 30 0.010
myotube differentiation GO:0014902 45 0.010
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.010
response to hydrogen peroxide GO:0042542 3 0.010
neural nucleus development GO:0048857 15 0.010
lipid storage GO:0019915 1 0.010
regulation of protein complex assembly GO:0043254 3 0.010
positive regulation of cell cycle GO:0045787 3 0.010
regulation of metabolic process GO:0019222 359 0.010
positive regulation of synapse assembly GO:0051965 1 0.010
regulation of protein import into nucleus GO:0042306 2 0.010
regulation of protein targeting GO:1903533 2 0.010
taxis GO:0042330 109 0.010
smad protein complex assembly GO:0007183 1 0.010
synaptic vesicle transport GO:0048489 1 0.010
axon development GO:0061564 166 0.010
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 2 0.010
negative regulation of jnk cascade GO:0046329 1 0.010
macromolecule biosynthetic process GO:0009059 227 0.010
regulation of neuron differentiation GO:0045664 56 0.010
nitric oxide biosynthetic process GO:0006809 2 0.010

phex disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.107
musculoskeletal system disease DOID:17 0 0.076
myopathy DOID:423 0 0.035
muscular disease DOID:0080000 0 0.035
muscle tissue disease DOID:66 0 0.035
nervous system disease DOID:863 0 0.011
centronuclear myopathy DOID:14717 0 0.010