Danio rerio

48 known processes

pho

phoenix

(Aliases: zgc:165381,hi43,wu:fi26c04,fi26c04)

pho biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
tube morphogenesis GO:0035239 349 0.200
lateral line system development GO:0048925 76 0.115
larval development GO:0002164 2 0.096
cell migration GO:0016477 237 0.092
embryonic organ development GO:0048568 381 0.085
response to drug GO:0042493 3 0.083
positive regulation of transport GO:0051050 2 0.080
digestive system development GO:0055123 289 0.071
multicellular organism growth GO:0035264 4 0.070
single organism localization GO:1902578 225 0.066
cellular component movement GO:0006928 335 0.065
cellular component disassembly GO:0022411 1 0.064
mechanosensory lateral line system development GO:0048881 49 0.064
regulation of glucose import GO:0046324 1 0.063
system process GO:0003008 185 0.062
morphogenesis of an epithelium GO:0002009 333 0.059
female sex differentiation GO:0046660 4 0.057
homeostatic process GO:0042592 142 0.056
sensory system development GO:0048880 76 0.054
cell motility GO:0048870 244 0.053
head development GO:0060322 303 0.051
locomotion GO:0040011 313 0.050
digestive tract development GO:0048565 265 0.047
sensory organ development GO:0007423 393 0.047
regulation of glial cell differentiation GO:0045685 4 0.046
response to chemical GO:0042221 320 0.044
death GO:0016265 121 0.043
embryonic organ morphogenesis GO:0048562 274 0.043
brain development GO:0007420 293 0.042
response to monosaccharide GO:0034284 3 0.039
cellular response to external stimulus GO:0071496 2 0.039
localization of cell GO:0051674 244 0.038
regulation of stem cell proliferation GO:0072091 2 0.038
dicarboxylic acid transport GO:0006835 1 0.037
atp catabolic process GO:0006200 4 0.037
aging GO:0007568 2 0.037
regulation of synapse organization GO:0050807 3 0.036
maintenance of location GO:0051235 4 0.036
female gonad development GO:0008585 4 0.036
cell part morphogenesis GO:0032990 246 0.036
regulation of binding GO:0051098 3 0.035
regulation of protein complex assembly GO:0043254 3 0.035
regulation of endothelial cell proliferation GO:0001936 1 0.034
posterior lateral line system development GO:0048915 46 0.034
cell projection organization GO:0030030 284 0.034
synaptic growth at neuromuscular junction GO:0051124 2 0.034
response to carbohydrate GO:0009743 3 0.034
signal transduction GO:0007165 455 0.033
positive regulation of cell cycle GO:0045787 3 0.033
regulation of cellular amino acid metabolic process GO:0006521 0 0.033
myeloid cell homeostasis GO:0002262 56 0.033
developmental growth GO:0048589 166 0.033
sensory organ morphogenesis GO:0090596 200 0.033
photoreceptor cell outer segment organization GO:0035845 9 0.032
single organism metabolic process GO:0044710 217 0.032
digestive tract morphogenesis GO:0048546 231 0.032
multi organism process GO:0051704 134 0.031
regulation of cell matrix adhesion GO:0001952 1 0.031
lipid storage GO:0019915 1 0.031
glucose import GO:0046323 2 0.030
neuron neuron synaptic transmission GO:0007270 1 0.030
ear development GO:0043583 127 0.029
cellular response to extracellular stimulus GO:0031668 2 0.029
response to salt stress GO:0009651 10 0.029
positive regulation of cellular amine metabolic process GO:0033240 0 0.029
positive regulation of protein complex assembly GO:0031334 2 0.028
single organism organelle organization GO:1902589 199 0.028
angiogenesis GO:0001525 158 0.028
regulation of localization GO:0032879 104 0.028
mesenchyme development GO:0060485 127 0.028
regulation of reactive oxygen species metabolic process GO:2000377 2 0.028
neurotransmitter transport GO:0006836 2 0.027
positive regulation of epithelial cell proliferation GO:0050679 1 0.027
cellular ketone metabolic process GO:0042180 11 0.027
stem cell differentiation GO:0048863 117 0.027
telomere organization GO:0032200 1 0.027
nonmotile primary cilium assembly GO:0035058 2 0.027
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.026
response to transition metal nanoparticle GO:1990267 28 0.026
vasculature development GO:0001944 278 0.026
regulation of cellular ketone metabolic process GO:0010565 7 0.026
phagocytosis GO:0006909 3 0.026
protein targeting to nucleus GO:0044744 3 0.025
steroid hormone secretion GO:0035929 1 0.025
ribonucleoside monophosphate catabolic process GO:0009158 4 0.025
nucleoside monophosphate catabolic process GO:0009125 4 0.025
development of primary female sexual characteristics GO:0046545 4 0.025
post embryonic organ development GO:0048569 4 0.025
cilium organization GO:0044782 71 0.025
biosynthetic process GO:0009058 294 0.025
stem cell proliferation GO:0072089 4 0.025
gastrulation GO:0007369 208 0.025
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.025
oxoacid metabolic process GO:0043436 31 0.025
posterior lateral line development GO:0048916 38 0.024
protein complex disassembly GO:0043241 1 0.024
spermatid development GO:0007286 2 0.024
response to external stimulus GO:0009605 264 0.024
positive regulation of muscle organ development GO:0048636 1 0.024
cellular response to oxygen levels GO:0071453 1 0.024
nuclear export GO:0051168 1 0.024
macromolecular complex disassembly GO:0032984 1 0.024
cellular amine metabolic process GO:0044106 2 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.024
reflex GO:0060004 2 0.023
small molecule metabolic process GO:0044281 77 0.023
regulation of protein binding GO:0043393 3 0.023
regulation of multicellular organism growth GO:0040014 4 0.023
response to amino acid GO:0043200 2 0.023
hormone transport GO:0009914 2 0.023
immune system development GO:0002520 191 0.023
protein import into nucleus GO:0006606 3 0.023
regulation of synapse assembly GO:0051963 3 0.023
medulla oblongata development GO:0021550 4 0.022
multicellular organismal signaling GO:0035637 22 0.022
regulation of glucose transport GO:0010827 1 0.022
positive regulation of protein kinase b signaling GO:0051897 1 0.022
negative regulation of biological process GO:0048519 304 0.022
cell morphogenesis GO:0000902 289 0.022
cellular response to hypoxia GO:0071456 1 0.022
regulation of hormone secretion GO:0046883 2 0.021
endocrine hormone secretion GO:0060986 2 0.021
glucose homeostasis GO:0042593 1 0.021
meiotic chromosome segregation GO:0045132 3 0.021
response to hexose GO:0009746 3 0.021
regulation of establishment of protein localization GO:0070201 4 0.021
cellular response to nutrient levels GO:0031669 2 0.020
single organism nuclear import GO:1902593 3 0.020
blood vessel morphogenesis GO:0048514 216 0.020
response to corticosteroid GO:0031960 1 0.020
regulation of myotube differentiation GO:0010830 2 0.020
positive regulation of secretion GO:0051047 1 0.020
regulation of cell substrate adhesion GO:0010810 1 0.020
autophagy GO:0006914 4 0.020
hemopoiesis GO:0030097 183 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
neuromast primordium migration GO:0048883 12 0.020
cellular response to starvation GO:0009267 1 0.020
positive regulation of histone modification GO:0031058 1 0.019
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.019
regulation of response to stimulus GO:0048583 269 0.019
nucleocytoplasmic transport GO:0006913 4 0.019
adherens junction organization GO:0034332 4 0.019
negative regulation of signal transduction in absence of ligand GO:1901099 1 0.019
epithelial tube morphogenesis GO:0060562 148 0.019
positive regulation of cellular component biogenesis GO:0044089 3 0.019
regulation of protein transport GO:0051223 3 0.019
stem cell maintenance GO:0019827 4 0.019
vestibular reflex GO:0060005 2 0.019
positive regulation of muscle cell differentiation GO:0051149 1 0.019
positive regulation of cytokine production GO:0001819 2 0.019
organonitrogen compound metabolic process GO:1901564 74 0.019
purine nucleoside monophosphate catabolic process GO:0009128 4 0.019
response to glucose GO:0009749 3 0.019
hormone secretion GO:0046879 2 0.019
ovulation cycle process GO:0022602 2 0.019
establishment of protein localization to organelle GO:0072594 4 0.019
rna localization GO:0006403 4 0.018
pigmentation GO:0043473 85 0.018
lateral line development GO:0048882 66 0.018
regulation of endocrine process GO:0044060 2 0.018
regulation of cytokine production GO:0001817 3 0.018
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.018
synaptic vesicle transport GO:0048489 1 0.018
regulation of biological quality GO:0065008 263 0.018
cell matrix adhesion GO:0007160 4 0.018
erythrocyte homeostasis GO:0034101 55 0.018
sulfate transmembrane transport GO:1902358 2 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
transmission of nerve impulse GO:0019226 19 0.018
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.018
negative regulation of dna recombination GO:0045910 2 0.018
posterior lateral line neuromast primordium migration GO:0048920 12 0.017
spermatid differentiation GO:0048515 2 0.017
regulation of skeletal muscle tissue development GO:0048641 4 0.017
signal transduction in absence of ligand GO:0038034 1 0.017
internal peptidyl lysine acetylation GO:0018393 2 0.017
cell substrate adhesion GO:0031589 4 0.017
negative regulation of secretion by cell GO:1903531 2 0.017
amine metabolic process GO:0009308 2 0.017
response to glucocorticoid GO:0051384 1 0.017
positive regulation of secretion by cell GO:1903532 1 0.017
synaptic vesicle localization GO:0097479 1 0.017
peptidyl lysine acetylation GO:0018394 2 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.017
mesenchymal cell development GO:0014031 78 0.017
central nervous system development GO:0007417 387 0.017
peptidyl serine modification GO:0018209 2 0.017
sleep GO:0030431 1 0.017
eye morphogenesis GO:0048592 144 0.016
endocrine process GO:0050886 2 0.016
mitochondrion organization GO:0007005 4 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.016
positive regulation of map kinase activity GO:0043406 3 0.016
neuroblast proliferation GO:0007405 2 0.016
camera type eye development GO:0043010 222 0.016
adult behavior GO:0030534 2 0.016
regulation of organ growth GO:0046620 3 0.016
mesenchymal cell differentiation GO:0048762 87 0.016
polarized epithelial cell differentiation GO:0030859 4 0.016
exocytosis GO:0006887 1 0.016
transcription from rna polymerase ii promoter GO:0006366 80 0.016
homeostasis of number of cells within a tissue GO:0048873 4 0.016
neurotransmitter secretion GO:0007269 2 0.016
single organism transport GO:0044765 206 0.016
protein metabolic process GO:0019538 183 0.016
positive regulation of cell matrix adhesion GO:0001954 1 0.016
myeloid cell differentiation GO:0030099 86 0.016
germ line stem cell division GO:0042078 1 0.016
regulation of metal ion transport GO:0010959 4 0.016
stem cell division GO:0017145 1 0.016
positive regulation of striated muscle cell differentiation GO:0051155 1 0.016
negative regulation of synapse assembly GO:0051964 2 0.016
positive regulation of muscle tissue development GO:1901863 1 0.015
chromosome organization involved in meiosis GO:0070192 1 0.015
positive regulation of gliogenesis GO:0014015 2 0.015
regulation of transmembrane transporter activity GO:0022898 2 0.015
cellular response to decreased oxygen levels GO:0036294 1 0.015
organelle localization GO:0051640 49 0.015
regulation of signaling GO:0023051 235 0.015
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.015
regulation of skeletal muscle fiber development GO:0048742 2 0.015
cartilage condensation GO:0001502 3 0.015
meiotic cell cycle process GO:1903046 3 0.015
cellular component assembly involved in morphogenesis GO:0010927 107 0.015
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
response to alkaloid GO:0043279 2 0.015
cellular response to reactive oxygen species GO:0034614 2 0.015
response to stress GO:0006950 263 0.015
negative regulation of catabolic process GO:0009895 3 0.015
positive regulation of catabolic process GO:0009896 4 0.015
regulation of cellular component organization GO:0051128 86 0.015
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.015
ovarian follicle development GO:0001541 2 0.015
nucleobase containing compound metabolic process GO:0006139 274 0.015
regulation of blood vessel size GO:0050880 2 0.015
startle response GO:0001964 4 0.014
negative regulation of secretion GO:0051048 2 0.014
positive regulation of protein polymerization GO:0032273 2 0.014
embryo development ending in birth or egg hatching GO:0009792 271 0.014
establishment of organelle localization GO:0051656 45 0.014
positive regulation of dna metabolic process GO:0051054 1 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
regulation of response to extracellular stimulus GO:0032104 1 0.014
regulation of autophagy GO:0010506 3 0.014
response to hydrogen peroxide GO:0042542 3 0.014
sodium ion transmembrane transport GO:0035725 21 0.014
cellular response to endogenous stimulus GO:0071495 68 0.014
ear morphogenesis GO:0042471 64 0.014
hematopoietic or lymphoid organ development GO:0048534 191 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
translational initiation GO:0006413 3 0.014
action potential GO:0001508 19 0.014
regulation of chromosome segregation GO:0051983 1 0.014
stem cell development GO:0048864 82 0.014
regulation of protein complex disassembly GO:0043244 1 0.014
camera type eye photoreceptor cell differentiation GO:0060219 19 0.013
homeostasis of number of cells GO:0048872 62 0.013
protein acetylation GO:0006473 2 0.013
positive regulation of striated muscle tissue development GO:0045844 1 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.013
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.013
entrainment of circadian clock by photoperiod GO:0043153 1 0.013
cellular protein modification process GO:0006464 100 0.013
convergent extension involved in gastrulation GO:0060027 71 0.013
carbohydrate homeostasis GO:0033500 1 0.013
internal protein amino acid acetylation GO:0006475 2 0.013
ameboidal type cell migration GO:0001667 143 0.013
regulation of blood pressure GO:0008217 1 0.013
vesicle localization GO:0051648 27 0.013
protein modification process GO:0036211 100 0.013
nuclear import GO:0051170 3 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
regulation of steroid hormone secretion GO:2000831 1 0.013
response to endogenous stimulus GO:0009719 83 0.013
neurological system process GO:0050877 62 0.013
response to inorganic substance GO:0010035 38 0.013
pigment granule localization GO:0051875 25 0.013
positive regulation of glucose transport GO:0010828 1 0.013
toxin transport GO:1901998 2 0.013
monoamine transport GO:0015844 1 0.013
circadian sleep wake cycle sleep GO:0050802 1 0.013
regulation of epithelial cell proliferation GO:0050678 3 0.013
histone h3 k9 methylation GO:0051567 5 0.013
embryonic skeletal joint development GO:0072498 3 0.013
chemosensory behavior GO:0007635 1 0.013
regulation of ph GO:0006885 3 0.013
spindle assembly GO:0051225 2 0.013
regulation of histone methylation GO:0031060 3 0.012
regulation of membrane potential GO:0042391 23 0.012
peptide metabolic process GO:0006518 1 0.012
b cell differentiation GO:0030183 1 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
cellular macromolecule metabolic process GO:0044260 391 0.012
smooth muscle tissue development GO:0048745 1 0.012
heterocycle metabolic process GO:0046483 290 0.012
regulation of production of molecular mediator of immune response GO:0002700 1 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
negative chemotaxis GO:0050919 1 0.012
positive regulation of endothelial cell proliferation GO:0001938 1 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
reactive oxygen species biosynthetic process GO:1903409 1 0.012
leukocyte proliferation GO:0070661 1 0.012
organic acid metabolic process GO:0006082 31 0.012
exocrine system development GO:0035272 28 0.012
cell projection morphogenesis GO:0048858 244 0.012
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.012
negative regulation of dna metabolic process GO:0051053 4 0.012
neuromast development GO:0048884 46 0.012
regulation of ion transmembrane transporter activity GO:0032412 2 0.012
chordate embryonic development GO:0043009 271 0.012
g protein coupled receptor signaling pathway GO:0007186 74 0.012
cellular protein complex disassembly GO:0043624 1 0.012
response to oxygen containing compound GO:1901700 55 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.012
negative regulation of gene expression GO:0010629 65 0.012
calcium ion import GO:0070509 4 0.012
primary neural tube formation GO:0014020 1 0.012
mitotic dna integrity checkpoint GO:0044774 4 0.012
glial cell proliferation GO:0014009 4 0.012
regulation of neuronal synaptic plasticity GO:0048168 1 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
hepaticobiliary system development GO:0061008 98 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.011
phosphatidylinositol mediated signaling GO:0048015 2 0.011
heterocycle biosynthetic process GO:0018130 215 0.011
negative regulation of cytoplasmic transport GO:1903650 2 0.011
detection of mechanical stimulus GO:0050982 11 0.011
dna templated transcription initiation GO:0006352 1 0.011
antimicrobial humoral response GO:0019730 2 0.011
regulation of protein catabolic process GO:0042176 1 0.011
establishment of vesicle localization GO:0051650 24 0.011
positive regulation of myeloid cell differentiation GO:0045639 2 0.011
regulation of tube size GO:0035150 2 0.011
protein acylation GO:0043543 3 0.011
maternal determination of anterior posterior axis embryo GO:0008358 4 0.011
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 4 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
regulation of lipase activity GO:0060191 2 0.011
regulation of reproductive process GO:2000241 4 0.011
cellular response to lipopolysaccharide GO:0071222 3 0.011
muscle cell migration GO:0014812 4 0.011
response to cadmium ion GO:0046686 14 0.011
cytoplasm organization GO:0007028 4 0.011
inner ear development GO:0048839 126 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
inositol lipid mediated signaling GO:0048017 2 0.011
response to nutrient GO:0007584 3 0.011
sulfur compound transport GO:0072348 3 0.011
hindbrain development GO:0030902 91 0.011
sodium ion transport GO:0006814 24 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.011
regulation of translational initiation GO:0006446 1 0.011
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.011
modification dependent macromolecule catabolic process GO:0043632 3 0.011
regulation of neural precursor cell proliferation GO:2000177 3 0.011
somatic stem cell maintenance GO:0035019 1 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
erythrocyte differentiation GO:0030218 54 0.011
single fertilization GO:0007338 3 0.011
blood circulation GO:0008015 87 0.011
regulation of cell activation GO:0050865 1 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
protein import GO:0017038 3 0.010
regulation of lipid transport GO:0032368 4 0.010
regulation of heart growth GO:0060420 2 0.010
circadian sleep wake cycle GO:0042745 2 0.010
lens fiber cell morphogenesis GO:0070309 3 0.010
synaptic target recognition GO:0008039 1 0.010
cellular response to dsrna GO:0071359 1 0.010
semicircular canal morphogenesis GO:0048752 18 0.010
protein localization to nucleus GO:0034504 3 0.010
positive regulation of immune effector process GO:0002699 3 0.010
carbohydrate transport GO:0008643 13 0.010
regulation of intracellular protein transport GO:0033157 3 0.010
monocyte differentiation GO:0030224 2 0.010
regulation of cytokine mediated signaling pathway GO:0001959 3 0.010
embryonic hemopoiesis GO:0035162 53 0.010
carboxylic acid metabolic process GO:0019752 22 0.010
retinal rod cell development GO:0046548 4 0.010
negative regulation of cellular process GO:0048523 283 0.010
heart morphogenesis GO:0003007 156 0.010
protein homooligomerization GO:0051260 3 0.010
circulatory system process GO:0003013 87 0.010
peptide transport GO:0015833 1 0.010
neuron development GO:0048666 262 0.010
neuronal action potential GO:0019228 18 0.010
response to antibiotic GO:0046677 1 0.010
organelle organization GO:0006996 227 0.010
response to organic substance GO:0010033 153 0.010
modification dependent protein catabolic process GO:0019941 3 0.010

pho disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.050
endocrine system disease DOID:28 0 0.029
musculoskeletal system disease DOID:17 0 0.026
disease of metabolism DOID:0014667 0 0.025
inherited metabolic disorder DOID:655 0 0.025
cardiovascular system disease DOID:1287 0 0.020
nervous system disease DOID:863 0 0.018
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
muscular disease DOID:0080000 0 0.013
myopathy DOID:423 0 0.012
muscle tissue disease DOID:66 0 0.012