Danio rerio

0 known processes

pik3c3

phosphoinositide-3-kinase, class 3

(Aliases: zgc:112016,wu:fc13g06,zgc:113009,MGC191642,im:7147158,wu:fz51e12)

pik3c3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
locomotion GO:0040011 313 0.202
Worm
neuron differentiation GO:0030182 353 0.154
larval development GO:0002164 2 0.145
Worm
aging GO:0007568 2 0.137
Worm
single organism organelle organization GO:1902589 199 0.093
neuron development GO:0048666 262 0.083
cellular protein catabolic process GO:0044257 4 0.078
regulation of signal transduction GO:0009966 225 0.077
negative regulation of cellular process GO:0048523 283 0.077
response to chemical GO:0042221 320 0.075
response to stress GO:0006950 263 0.075
membrane fusion GO:0061025 2 0.074
phagocytosis GO:0006909 3 0.071
Worm
cell projection organization GO:0030030 284 0.069
guanosine containing compound metabolic process GO:1901068 4 0.063
cell part morphogenesis GO:0032990 246 0.063
maintenance of location GO:0051235 4 0.060
negative regulation of biological process GO:0048519 304 0.059
neuron projection development GO:0031175 180 0.059
nucleoside monophosphate catabolic process GO:0009125 4 0.057
generation of neurons GO:0048699 385 0.056
purine nucleoside monophosphate catabolic process GO:0009128 4 0.054
cellular aromatic compound metabolic process GO:0006725 295 0.054
organic cyclic compound metabolic process GO:1901360 301 0.053
organelle fusion GO:0048284 3 0.052
response to external stimulus GO:0009605 264 0.051
organelle organization GO:0006996 227 0.051
Worm
ribonucleoside monophosphate catabolic process GO:0009158 4 0.051
small molecule metabolic process GO:0044281 77 0.049
positive regulation of cellular catabolic process GO:0031331 3 0.048
establishment of localization GO:0051234 244 0.047
Worm
cell projection morphogenesis GO:0048858 244 0.046
atp catabolic process GO:0006200 4 0.046
cellular component movement GO:0006928 335 0.045
regulation of epithelial cell proliferation GO:0050678 3 0.044
neuron projection morphogenesis GO:0048812 161 0.044
cellular component disassembly GO:0022411 1 0.043
positive regulation of catabolic process GO:0009896 4 0.042
cellular nitrogen compound metabolic process GO:0034641 290 0.042
single organism membrane fusion GO:0044801 2 0.042
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.041
positive regulation of biological process GO:0048518 253 0.041
Worm
cell death GO:0008219 121 0.040
nitrogen compound metabolic process GO:0006807 319 0.040
cellular response to chemical stimulus GO:0070887 157 0.039
gtp metabolic process GO:0046039 4 0.038
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.038
microtubule based process GO:0007017 60 0.037
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.037
regulation of developmental process GO:0050793 247 0.037
heterocycle metabolic process GO:0046483 290 0.036
regulation of rna metabolic process GO:0051252 224 0.036
positive regulation of transport GO:0051050 2 0.035
Worm
modification dependent protein catabolic process GO:0019941 3 0.035
microtubule depolymerization GO:0007019 1 0.035
protein complex disassembly GO:0043241 1 0.035
cellular macromolecule metabolic process GO:0044260 391 0.035
macromolecular complex disassembly GO:0032984 1 0.034
death GO:0016265 121 0.034
cellular response to nutrient levels GO:0031669 2 0.033
single organism metabolic process GO:0044710 217 0.033
Worm
axon development GO:0061564 166 0.033
regulation of cell communication GO:0010646 232 0.032
signal transduction GO:0007165 455 0.032
organonitrogen compound metabolic process GO:1901564 74 0.031
apoptotic process GO:0006915 116 0.031
modification dependent macromolecule catabolic process GO:0043632 3 0.031
cell substrate adhesion GO:0031589 4 0.031
autophagy GO:0006914 4 0.031
Worm
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.031
cellular response to external stimulus GO:0071496 2 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.030
regulation of macromolecule metabolic process GO:0060255 317 0.030
gtp catabolic process GO:0006184 2 0.030
cell morphogenesis involved in differentiation GO:0000904 195 0.029
regulation of cell differentiation GO:0045595 142 0.029
ubiquitin dependent protein catabolic process GO:0006511 3 0.029
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.028
axonogenesis GO:0007409 152 0.028
regulation of protein complex assembly GO:0043254 3 0.028
cellular response to starvation GO:0009267 1 0.028
regulation of protein catabolic process GO:0042176 1 0.028
regulation of protein depolymerization GO:1901879 1 0.028
regulation of cell projection organization GO:0031344 44 0.027
regulation of microtubule cytoskeleton organization GO:0070507 3 0.027
digestive system development GO:0055123 289 0.027
regulation of nucleoside metabolic process GO:0009118 2 0.027
dorsal ventral pattern formation GO:0009953 125 0.027
positive regulation of cell cycle GO:0045787 3 0.027
cell morphogenesis GO:0000902 289 0.027
cytoskeleton organization GO:0007010 96 0.027
meiotic nuclear division GO:0007126 4 0.027
regulation of purine nucleotide catabolic process GO:0033121 2 0.027
catabolic process GO:0009056 32 0.026
Worm
establishment of protein localization to organelle GO:0072594 4 0.026
microtubule polymerization or depolymerization GO:0031109 3 0.026
endosomal transport GO:0016197 2 0.026
multicellular organism growth GO:0035264 4 0.026
cellular response to extracellular stimulus GO:0031668 2 0.026
locomotor rhythm GO:0045475 3 0.025
cellular localization GO:0051641 97 0.025
Worm
positive regulation of secretion by cell GO:1903532 1 0.025
rna metabolic process GO:0016070 219 0.025
regulation of synapse organization GO:0050807 3 0.025
regulation of biosynthetic process GO:0009889 250 0.025
compound eye development GO:0048749 2 0.025
regulation of primary metabolic process GO:0080090 311 0.025
negative regulation of protein phosphorylation GO:0001933 4 0.024
phosphate containing compound metabolic process GO:0006796 108 0.024
Worm
cytoplasm organization GO:0007028 4 0.024
transport GO:0006810 220 0.024
Worm
lipid storage GO:0019915 1 0.024
positive regulation of apoptotic signaling pathway GO:2001235 1 0.024
regulation of signaling GO:0023051 235 0.024
regulation of gene expression GO:0010468 265 0.024
membrane invagination GO:0010324 1 0.023
Worm
regulation of stem cell proliferation GO:0072091 2 0.023
stem cell proliferation GO:0072089 4 0.023
cellular biosynthetic process GO:0044249 286 0.023
Worm
regulation of protein complex disassembly GO:0043244 1 0.023
atp synthesis coupled electron transport GO:0042773 1 0.023
microtubule cytoskeleton organization GO:0000226 33 0.023
synaptic vesicle localization GO:0097479 1 0.022
regulation of establishment of protein localization GO:0070201 4 0.022
Worm
regulation of multicellular organismal process GO:0051239 277 0.022
protein polymerization GO:0051258 4 0.022
gene expression GO:0010467 252 0.022
regulation of rna biosynthetic process GO:2001141 213 0.022
vasculature development GO:0001944 278 0.021
positive regulation of stem cell proliferation GO:2000648 1 0.021
embryonic organ development GO:0048568 381 0.021
regulation of protein ubiquitination GO:0031396 3 0.021
regulation of cell development GO:0060284 100 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
cellular component morphogenesis GO:0032989 336 0.021
stem cell division GO:0017145 1 0.021
multi organism process GO:0051704 134 0.021
regulation of multicellular organismal development GO:2000026 223 0.021
negative regulation of epithelial cell proliferation GO:0050680 1 0.020
embryo development ending in birth or egg hatching GO:0009792 271 0.020
rna localization GO:0006403 4 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
cell migration GO:0016477 237 0.020
sensory organ development GO:0007423 393 0.020
cell cycle g2 m phase transition GO:0044839 4 0.020
regulation of nervous system development GO:0051960 90 0.020
protein depolymerization GO:0051261 1 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
regulation of nitrogen compound metabolic process GO:0051171 251 0.020
smoothened signaling pathway GO:0007224 30 0.020
regulation of meiotic cell cycle GO:0051445 1 0.020
regulation of protein transport GO:0051223 3 0.020
Worm
meiotic chromosome segregation GO:0045132 3 0.019
chemotaxis GO:0006935 104 0.019
lateral inhibition GO:0046331 1 0.019
regulation of neuron projection development GO:0010975 40 0.019
positive regulation of neuron projection development GO:0010976 9 0.019
single organism transport GO:0044765 206 0.019
Worm
proteasomal protein catabolic process GO:0010498 2 0.019
regulation of neuron differentiation GO:0045664 56 0.019
regulation of cell substrate adhesion GO:0010810 1 0.019
embryonic limb morphogenesis GO:0030326 2 0.019
single organism localization GO:1902578 225 0.019
Worm
cellular amine metabolic process GO:0044106 2 0.019
connective tissue development GO:0061448 99 0.019
g2 m transition of mitotic cell cycle GO:0000086 4 0.019
negative regulation of intracellular protein transport GO:0090317 3 0.019
cellular macromolecule biosynthetic process GO:0034645 224 0.019
regulation of apoptotic process GO:0042981 98 0.019
regulation of organ growth GO:0046620 3 0.019
positive regulation of secretion GO:0051047 1 0.019
positive regulation of cell adhesion GO:0045785 1 0.018
guanosine containing compound catabolic process GO:1901069 2 0.018
amine metabolic process GO:0009308 2 0.018
phosphorus metabolic process GO:0006793 109 0.018
Worm
macroautophagy GO:0016236 1 0.018
intracellular signal transduction GO:0035556 85 0.018
regulation of gtpase activity GO:0043087 2 0.018
endosome organization GO:0007032 2 0.018
macromolecular complex subunit organization GO:0043933 74 0.018
regulation of response to stimulus GO:0048583 269 0.018
regulation of neurogenesis GO:0050767 87 0.018
cellular catabolic process GO:0044248 27 0.018
Worm
synaptic vesicle transport GO:0048489 1 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
cell motility GO:0048870 244 0.018
liver development GO:0001889 96 0.017
nucleobase containing compound metabolic process GO:0006139 274 0.017
digestive tract development GO:0048565 265 0.017
morphogenesis of an epithelium GO:0002009 333 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
regulation of metabolic process GO:0019222 359 0.017
Worm
vacuolar transport GO:0007034 2 0.017
regionalization GO:0003002 274 0.017
aromatic compound biosynthetic process GO:0019438 217 0.017
gland development GO:0048732 143 0.017
regulation of reproductive process GO:2000241 4 0.017
protein localization to plasma membrane GO:0072659 1 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
glial cell proliferation GO:0014009 4 0.017
response to topologically incorrect protein GO:0035966 2 0.017
transcription dna templated GO:0006351 181 0.017
negative regulation of protein kinase activity GO:0006469 4 0.017
positive regulation of response to stimulus GO:0048584 80 0.017
secondary metabolic process GO:0019748 3 0.017
wnt signaling pathway GO:0016055 80 0.017
protein secretion GO:0009306 1 0.017
Worm
regulation of microtubule depolymerization GO:0031114 1 0.017
purine containing compound metabolic process GO:0072521 29 0.017
segmentation GO:0035282 97 0.017
single organism cellular localization GO:1902580 46 0.017
regulation of gtp catabolic process GO:0033124 2 0.017
protein metabolic process GO:0019538 183 0.017
nucleic acid metabolic process GO:0090304 244 0.016
positive regulation of cellular process GO:0048522 201 0.016
Worm
mitotic dna integrity checkpoint GO:0044774 4 0.016
nucleobase containing small molecule metabolic process GO:0055086 32 0.016
positive regulation of nucleotide catabolic process GO:0030813 1 0.016
g2 dna damage checkpoint GO:0031572 3 0.016
cell projection assembly GO:0030031 64 0.016
negative regulation of protein complex assembly GO:0031333 1 0.016
regulation of wound healing GO:0061041 2 0.016
ribose phosphate metabolic process GO:0019693 27 0.016
carboxylic acid metabolic process GO:0019752 22 0.016
eye development GO:0001654 277 0.016
adult behavior GO:0030534 2 0.016
regulation of organelle assembly GO:1902115 4 0.016
sensory organ morphogenesis GO:0090596 200 0.016
camera type eye development GO:0043010 222 0.016
cell surface receptor signaling pathway GO:0007166 325 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
protein import GO:0017038 3 0.015
regulation of anatomical structure morphogenesis GO:0022603 130 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.015
cellular component biogenesis GO:0044085 178 0.015
adherens junction organization GO:0034332 4 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.015
establishment of organelle localization GO:0051656 45 0.015
blood circulation GO:0008015 87 0.015
nucleocytoplasmic transport GO:0006913 4 0.015
female sex differentiation GO:0046660 4 0.015
mitochondrion organization GO:0007005 4 0.015
regulation of cellular metabolic process GO:0031323 320 0.015
taxis GO:0042330 109 0.015
heterocycle biosynthetic process GO:0018130 215 0.015
response to drug GO:0042493 3 0.015
regulation of carbohydrate metabolic process GO:0006109 4 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
establishment of localization in cell GO:0051649 77 0.015
Worm
regulation of cytokine production GO:0001817 3 0.015
macromolecule modification GO:0043412 111 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
cellular ketone metabolic process GO:0042180 11 0.015
organic acid metabolic process GO:0006082 31 0.015
embryonic organ morphogenesis GO:0048562 274 0.015
cellular carbohydrate metabolic process GO:0044262 4 0.015
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.014
phagocytosis engulfment GO:0006911 1 0.014
Worm
head development GO:0060322 303 0.014
positive regulation of wound healing GO:0090303 1 0.014
cellular respiration GO:0045333 3 0.014
positive regulation of gtp catabolic process GO:0033126 1 0.014
nuclear import GO:0051170 3 0.014
cell matrix adhesion GO:0007160 4 0.014
peptidyl serine phosphorylation GO:0018105 1 0.014
cell aging GO:0007569 2 0.014
cellular protein complex disassembly GO:0043624 1 0.014
cellular response to stress GO:0033554 62 0.014
response to endogenous stimulus GO:0009719 83 0.014
exocytosis GO:0006887 1 0.014
regulation of autophagy GO:0010506 3 0.014
protein dephosphorylation GO:0006470 3 0.014
regulation of transcription dna templated GO:0006355 213 0.014
melanin metabolic process GO:0006582 2 0.014
response to organic substance GO:0010033 153 0.014
nucleobase containing compound biosynthetic process GO:0034654 205 0.014
regulation of cell shape GO:0008360 1 0.014
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
stem cell maintenance GO:0019827 4 0.013
protein complex subunit organization GO:0071822 46 0.013
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.013
positive regulation of cellular component biogenesis GO:0044089 3 0.013
meiotic cell cycle process GO:1903046 3 0.013
mitotic g2 m transition checkpoint GO:0044818 3 0.013
regulation of wnt signaling pathway GO:0030111 53 0.013
nucleic acid templated transcription GO:0097659 181 0.013
cellular response to radiation GO:0071478 4 0.013
organelle localization GO:0051640 49 0.013
regulation of protein targeting GO:1903533 2 0.013
single fertilization GO:0007338 3 0.013
multicellular organismal signaling GO:0035637 22 0.013
regulation of cellular component organization GO:0051128 86 0.013
Worm
central nervous system development GO:0007417 387 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.013
protein targeting to nucleus GO:0044744 3 0.013
protein modification process GO:0036211 100 0.013
neuronal action potential GO:0019228 18 0.013
localization of cell GO:0051674 244 0.013
oxoacid metabolic process GO:0043436 31 0.013
growth GO:0040007 174 0.013
Worm
regulation of dendrite morphogenesis GO:0048814 3 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
lamellipodium assembly GO:0030032 1 0.012
establishment of synaptic vesicle localization GO:0097480 1 0.012
lamellipodium organization GO:0097581 1 0.012
establishment of protein localization to vacuole GO:0072666 1 0.012
hormone transport GO:0009914 2 0.012
biosynthetic process GO:0009058 294 0.012
Worm
regulation of multicellular organism growth GO:0040014 4 0.012
macromolecule biosynthetic process GO:0009059 227 0.012
system process GO:0003008 185 0.012
developmental maturation GO:0021700 34 0.012
cartilage development GO:0051216 96 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.012
regulation of hormone secretion GO:0046883 2 0.012
cellular component assembly GO:0022607 170 0.012
microtubule based movement GO:0007018 33 0.012
transmission of nerve impulse GO:0019226 19 0.012
negative regulation of metabolic process GO:0009892 86 0.012
intracellular mrna localization GO:0008298 1 0.012
regulation of rho protein signal transduction GO:0035023 2 0.012
regulation of organelle organization GO:0033043 29 0.012
protein homooligomerization GO:0051260 3 0.012
positive regulation of blood circulation GO:1903524 2 0.012
regulation of circadian rhythm GO:0042752 4 0.012
regulation of cellular biosynthetic process GO:0031326 245 0.012
spermatid development GO:0007286 2 0.012
organophosphate metabolic process GO:0019637 37 0.012
Worm
negative regulation of mapk cascade GO:0043409 4 0.012
sex determination GO:0007530 1 0.012
neuroblast proliferation GO:0007405 2 0.012
carbohydrate derivative metabolic process GO:1901135 61 0.012
regulation of protein polymerization GO:0032271 2 0.012
response to lipid GO:0033993 60 0.012
wound healing GO:0042060 90 0.012
protein acetylation GO:0006473 2 0.012
cellular response to light stimulus GO:0071482 4 0.012
specification of symmetry GO:0009799 204 0.012
single organism membrane organization GO:0044802 20 0.012
Worm
regulation of synapse assembly GO:0051963 3 0.012
macromolecule localization GO:0033036 54 0.012
Worm
rho protein signal transduction GO:0007266 5 0.012
heart morphogenesis GO:0003007 156 0.012
brain development GO:0007420 293 0.012
chromosome organization involved in meiosis GO:0070192 1 0.011
nuclear transport GO:0051169 4 0.011
appendage development GO:0048736 80 0.011
positive regulation of metabolic process GO:0009893 108 0.011
Worm
protein acylation GO:0043543 3 0.011
female gonad development GO:0008585 4 0.011
response to glucose GO:0009749 3 0.011
determination of bilateral symmetry GO:0009855 204 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
mitotic cell cycle GO:0000278 64 0.011
regulation of biological quality GO:0065008 263 0.011
rna biosynthetic process GO:0032774 181 0.011
regulation of dendrite development GO:0050773 3 0.011
digestive tract morphogenesis GO:0048546 231 0.011
regulation of binding GO:0051098 3 0.011
developmental growth GO:0048589 166 0.011
regulation of ras gtpase activity GO:0032318 2 0.011
negative regulation of signaling GO:0023057 96 0.011
response to monosaccharide GO:0034284 3 0.011
protein localization to vacuole GO:0072665 1 0.011
single organism nuclear import GO:1902593 3 0.011
regulation of nucleic acid templated transcription GO:1903506 213 0.011
negative regulation of map kinase activity GO:0043407 2 0.011
cellular protein modification process GO:0006464 100 0.011
regulation of programmed cell death GO:0043067 101 0.011
cytokinesis GO:0000910 3 0.011
positive regulation of cell projection organization GO:0031346 9 0.011
cell substrate junction assembly GO:0007044 2 0.011
pectoral fin development GO:0033339 50 0.011
regulation of chromosome segregation GO:0051983 1 0.011
protein localization to nucleus GO:0034504 3 0.011
tissue remodeling GO:0048771 4 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
activation of mapk activity GO:0000187 3 0.011
retina development in camera type eye GO:0060041 146 0.011
protein targeting to vacuole GO:0006623 1 0.011
positive regulation of multicellular organismal process GO:0051240 52 0.011
homeostatic process GO:0042592 142 0.011
cilium assembly GO:0042384 58 0.011
positive regulation of cell activation GO:0050867 1 0.011
organic substance biosynthetic process GO:1901576 289 0.011
Worm
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.011
post golgi vesicle mediated transport GO:0006892 1 0.011
cellular response to endogenous stimulus GO:0071495 68 0.010
regulation of cell activation GO:0050865 1 0.010
epithelial cell morphogenesis GO:0003382 2 0.010
peptidyl threonine phosphorylation GO:0018107 1 0.010
negative regulation of multi organism process GO:0043901 3 0.010
organic substance catabolic process GO:1901575 28 0.010
regulation of protein import into nucleus GO:0042306 2 0.010
cellular nitrogen compound biosynthetic process GO:0044271 218 0.010
action potential GO:0001508 19 0.010
lipid homeostasis GO:0055088 3 0.010
negative regulation of signal transduction GO:0009968 94 0.010
protein import into nucleus GO:0006606 3 0.010
regulation of cellular component movement GO:0051270 55 0.010
hormone secretion GO:0046879 2 0.010
mitochondrion morphogenesis GO:0070584 2 0.010
regulation of jak stat cascade GO:0046425 3 0.010
rna transport GO:0050658 2 0.010
actin filament polymerization GO:0030041 2 0.010
regulation of cell matrix adhesion GO:0001952 1 0.010
regulation of exocytosis GO:0017157 1 0.010
organic cyclic compound biosynthetic process GO:1901362 223 0.010
nuclear migration GO:0007097 3 0.010

pik3c3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.014
cancer DOID:162 0 0.014