Danio rerio

34 known processes

pitpna

phosphatidylinositol transfer protein, alpha

(Aliases: Pitpn,MGC55569,zgc:55569)

pitpna biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
membrane lipid biosynthetic process GO:0046467 2 0.292
sphingolipid biosynthetic process GO:0030148 2 0.134
single organism localization GO:1902578 225 0.129
establishment of protein localization to organelle GO:0072594 4 0.109
organonitrogen compound metabolic process GO:1901564 74 0.098
aging GO:0007568 2 0.090
positive regulation of transport GO:0051050 2 0.088
regulation of protein localization to nucleus GO:1900180 2 0.085
response to drug GO:0042493 3 0.081
maintenance of location GO:0051235 4 0.076
carboxylic acid metabolic process GO:0019752 22 0.075
sensory organ development GO:0007423 393 0.072
single organism carbohydrate metabolic process GO:0044723 12 0.071
long chain fatty acid biosynthetic process GO:0042759 1 0.069
cellular component movement GO:0006928 335 0.066
single organism metabolic process GO:0044710 217 0.063
regulation of cytoplasmic transport GO:1903649 4 0.060
regulation of cytokine production GO:0001817 3 0.060
regulation of protein transport GO:0051223 3 0.059
single organism transport GO:0044765 206 0.057
multicellular organism growth GO:0035264 4 0.057
fatty acid elongation GO:0030497 1 0.056
regulation of protein complex assembly GO:0043254 3 0.055
actin polymerization or depolymerization GO:0008154 2 0.055
regulation of anatomical structure size GO:0090066 33 0.054
ceramide biosynthetic process GO:0046513 1 0.054
regulation of establishment of protein localization GO:0070201 4 0.053
biosynthetic process GO:0009058 294 0.052
protein polymerization GO:0051258 4 0.051
organelle organization GO:0006996 227 0.049
regulation of protein polymerization GO:0032271 2 0.049
regulation of protein import into nucleus GO:0042306 2 0.049
regulation of nucleocytoplasmic transport GO:0046822 2 0.047
eye development GO:0001654 277 0.046
very long chain fatty acid biosynthetic process GO:0042761 4 0.045
fatty acid elongation unsaturated fatty acid GO:0019368 1 0.045
regulation of signaling GO:0023051 235 0.044
ubiquitin dependent protein catabolic process GO:0006511 3 0.044
negative regulation of cellular process GO:0048523 283 0.043
establishment of localization in cell GO:0051649 77 0.043
regulation of protein targeting GO:1903533 2 0.041
membrane lipid metabolic process GO:0006643 10 0.041
cellular protein metabolic process GO:0044267 129 0.041
peptide transport GO:0015833 1 0.041
central nervous system development GO:0007417 387 0.040
mitochondrion organization GO:0007005 4 0.039
single organism nuclear import GO:1902593 3 0.039
protein targeting to nucleus GO:0044744 3 0.038
cellular macromolecule metabolic process GO:0044260 391 0.037
cellular amino acid metabolic process GO:0006520 7 0.037
regulation of biological quality GO:0065008 263 0.036
extrinsic apoptotic signaling pathway GO:0097191 3 0.036
nucleocytoplasmic transport GO:0006913 4 0.035
protein localization to nucleus GO:0034504 3 0.035
positive regulation of protein complex assembly GO:0031334 2 0.034
blood vessel morphogenesis GO:0048514 216 0.034
organic acid metabolic process GO:0006082 31 0.034
regulation of neurotransmitter secretion GO:0046928 1 0.034
hydrogen peroxide metabolic process GO:0042743 2 0.034
positive regulation of cellular component biogenesis GO:0044089 3 0.033
cytokinesis GO:0000910 3 0.033
actin cytoskeleton organization GO:0030036 63 0.033
response to external stimulus GO:0009605 264 0.033
gtp metabolic process GO:0046039 4 0.033
negative regulation of biological process GO:0048519 304 0.032
protein import GO:0017038 3 0.032
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.032
larval development GO:0002164 2 0.031
regulation of intracellular protein transport GO:0033157 3 0.031
cellular protein catabolic process GO:0044257 4 0.031
locomotion GO:0040011 313 0.031
positive regulation of cytoskeleton organization GO:0051495 3 0.031
regulation of ion transmembrane transporter activity GO:0032412 2 0.030
modification dependent protein catabolic process GO:0019941 3 0.030
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.030
positive regulation of cytokine production GO:0001819 2 0.030
macromolecular complex subunit organization GO:0043933 74 0.030
lipid storage GO:0019915 1 0.029
regulation of sequestering of calcium ion GO:0051282 4 0.029
single organism biosynthetic process GO:0044711 71 0.029
negative regulation of cysteine type endopeptidase activity GO:2000117 8 0.028
signal transduction GO:0007165 455 0.028
lymphocyte proliferation GO:0046651 1 0.027
regulation of cell communication GO:0010646 232 0.027
nuclear import GO:0051170 3 0.027
regulation of neurotransmitter transport GO:0051588 1 0.027
synaptic vesicle transport GO:0048489 1 0.027
protein import into nucleus GO:0006606 3 0.027
camera type eye development GO:0043010 222 0.027
negative regulation of protein phosphorylation GO:0001933 4 0.026
protein complex localization GO:0031503 1 0.026
mitochondrial transport GO:0006839 2 0.026
endosome organization GO:0007032 2 0.026
intracellular transport GO:0046907 32 0.026
response to other organism GO:0051707 97 0.026
single organism intracellular transport GO:1902582 25 0.026
regulation of multicellular organism growth GO:0040014 4 0.026
cellular component biogenesis GO:0044085 178 0.026
vasculature development GO:0001944 278 0.026
protein metabolic process GO:0019538 183 0.025
cellular aromatic compound metabolic process GO:0006725 295 0.025
response to stress GO:0006950 263 0.025
carbohydrate metabolic process GO:0005975 12 0.025
response to biotic stimulus GO:0009607 97 0.025
transport GO:0006810 220 0.025
small molecule metabolic process GO:0044281 77 0.025
cellular response to organic substance GO:0071310 105 0.024
regulation of innate immune response GO:0045088 11 0.024
regulation of nucleotide catabolic process GO:0030811 2 0.024
cellular component assembly GO:0022607 170 0.024
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.024
cell projection organization GO:0030030 284 0.024
cellular carbohydrate metabolic process GO:0044262 4 0.023
membrane fusion GO:0061025 2 0.023
establishment of localization GO:0051234 244 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.023
nitrogen compound metabolic process GO:0006807 319 0.023
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.022
synaptic vesicle localization GO:0097479 1 0.022
oxoacid metabolic process GO:0043436 31 0.022
regulation of nucleoside metabolic process GO:0009118 2 0.022
establishment of synaptic vesicle localization GO:0097480 1 0.022
dicarboxylic acid metabolic process GO:0043648 1 0.022
cellular amine metabolic process GO:0044106 2 0.022
response to amino acid GO:0043200 2 0.021
organic substance biosynthetic process GO:1901576 289 0.021
response to unfolded protein GO:0006986 2 0.021
cellular ketone metabolic process GO:0042180 11 0.021
regulation of calcium ion transport GO:0051924 2 0.021
localization of cell GO:0051674 244 0.021
nuclear transport GO:0051169 4 0.021
cell death GO:0008219 121 0.020
Worm
brain development GO:0007420 293 0.020
xenobiotic metabolic process GO:0006805 4 0.020
immune system process GO:0002376 241 0.020
regulation of cellular amine metabolic process GO:0033238 0 0.020
multi organism process GO:0051704 134 0.020
axonogenesis GO:0007409 152 0.019
regulation of response to stimulus GO:0048583 269 0.019
gtp catabolic process GO:0006184 2 0.019
positive regulation of immune effector process GO:0002699 3 0.019
regulation of blood vessel size GO:0050880 2 0.019
embryo development ending in birth or egg hatching GO:0009792 271 0.019
Worm
response to external biotic stimulus GO:0043207 97 0.019
negative regulation of cytoplasmic transport GO:1903650 2 0.019
anion transport GO:0006820 38 0.019
proteasomal protein catabolic process GO:0010498 2 0.018
cell motility GO:0048870 244 0.018
muscle structure development GO:0061061 196 0.018
positive regulation of catabolic process GO:0009896 4 0.018
proteolysis GO:0006508 38 0.018
regulation of cell activation GO:0050865 1 0.018
cellular biosynthetic process GO:0044249 286 0.018
ameboidal type cell migration GO:0001667 143 0.017
cellular nitrogen compound metabolic process GO:0034641 290 0.017
cell surface receptor signaling pathway GO:0007166 325 0.017
negative regulation of cytokine production GO:0001818 1 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
regulation of binding GO:0051098 3 0.017
blood circulation GO:0008015 87 0.017
positive regulation of jnk cascade GO:0046330 3 0.017
organic cyclic compound metabolic process GO:1901360 301 0.017
hepaticobiliary system development GO:0061008 98 0.017
heart process GO:0003015 71 0.017
amine metabolic process GO:0009308 2 0.017
cellular response to chemical stimulus GO:0070887 157 0.017
guanosine containing compound metabolic process GO:1901068 4 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
generation of neurons GO:0048699 385 0.016
negative regulation of protein transport GO:0051224 3 0.016
response to monosaccharide GO:0034284 3 0.016
regulation of protein catabolic process GO:0042176 1 0.016
multicellular organism reproduction GO:0032504 35 0.016
internal protein amino acid acetylation GO:0006475 2 0.016
positive regulation of protein polymerization GO:0032273 2 0.016
regulation of cellular component organization GO:0051128 86 0.016
cellular nitrogen compound biosynthetic process GO:0044271 218 0.016
positive regulation of cellular catabolic process GO:0031331 3 0.015
defense response to fungus GO:0050832 2 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
mononuclear cell proliferation GO:0032943 1 0.015
phosphate containing compound metabolic process GO:0006796 108 0.015
negative regulation of kinase activity GO:0033673 4 0.015
heterocycle metabolic process GO:0046483 290 0.015
cellular component morphogenesis GO:0032989 336 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
transmembrane transport GO:0055085 120 0.015
regulation of transmembrane transporter activity GO:0022898 2 0.015
cellular modified amino acid metabolic process GO:0006575 3 0.015
positive regulation of nucleoside metabolic process GO:0045979 1 0.015
leukocyte mediated cytotoxicity GO:0001909 1 0.015
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
macromolecule modification GO:0043412 111 0.014
endomembrane system organization GO:0010256 13 0.014
neurotransmitter transport GO:0006836 2 0.014
negative regulation of intracellular transport GO:0032387 3 0.014
organelle fusion GO:0048284 3 0.014
protein complex biogenesis GO:0070271 30 0.014
regulation of reproductive process GO:2000241 4 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
leukocyte proliferation GO:0070661 1 0.014
acylglycerol homeostasis GO:0055090 2 0.014
collagen metabolic process GO:0032963 2 0.014
negative regulation of response to stimulus GO:0048585 104 0.014
actin filament based process GO:0030029 64 0.014
response to hexose GO:0009746 3 0.014
modification dependent macromolecule catabolic process GO:0043632 3 0.014
regulation of endopeptidase activity GO:0052548 23 0.014
organonitrogen compound biosynthetic process GO:1901566 47 0.014
microtubule polymerization GO:0046785 2 0.014
negative regulation of defense response GO:0031348 2 0.013
immune effector process GO:0002252 23 0.013
cytosolic calcium ion transport GO:0060401 3 0.013
regulation of cell motility GO:2000145 46 0.013
positive regulation of cellular process GO:0048522 201 0.013
developmental growth GO:0048589 166 0.013
fatty acid biosynthetic process GO:0006633 4 0.013
protein localization to plasma membrane GO:0072659 1 0.013
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.013
negative regulation of intracellular protein transport GO:0090317 3 0.013
guanosine containing compound catabolic process GO:1901069 2 0.013
lipid metabolic process GO:0006629 52 0.013
cellular amide metabolic process GO:0043603 4 0.013
negative regulation of molecular function GO:0044092 23 0.013
smooth muscle contraction GO:0006939 2 0.013
regulation of proteolysis GO:0030162 24 0.013
ion transport GO:0006811 114 0.013
catabolic process GO:0009056 32 0.013
er nucleus signaling pathway GO:0006984 2 0.012
ovulation cycle GO:0042698 2 0.012
regulation of tube size GO:0035150 2 0.012
cellular protein modification process GO:0006464 100 0.012
negative regulation of signal transduction GO:0009968 94 0.012
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.012
regulation of oligodendrocyte differentiation GO:0048713 1 0.012
regulation of macromolecule metabolic process GO:0060255 317 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.012
regulation of blood pressure GO:0008217 1 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
macromolecular complex assembly GO:0065003 35 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
response to alkaloid GO:0043279 2 0.012
defense response GO:0006952 47 0.012
negative regulation of proteolysis GO:0045861 10 0.012
multicellular organismal response to stress GO:0033555 2 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
regulation of muscle contraction GO:0006937 3 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.012
epithelial cell differentiation GO:0030855 116 0.012
peptide metabolic process GO:0006518 1 0.012
positive regulation of apoptotic signaling pathway GO:2001235 1 0.012
response to topologically incorrect protein GO:0035966 2 0.012
protein localization GO:0008104 40 0.012
regulation of production of molecular mediator of immune response GO:0002700 1 0.012
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.012
regulation of phosphate metabolic process GO:0019220 43 0.011
regulation of programmed cell death GO:0043067 101 0.011
single organism organelle organization GO:1902589 199 0.011
cell cell recognition GO:0009988 1 0.011
cellular macromolecular complex assembly GO:0034622 24 0.011
striated muscle cell differentiation GO:0051146 129 0.011
s adenosylmethionine metabolic process GO:0046500 1 0.011
response to chemical GO:0042221 320 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
extracellular structure organization GO:0043062 27 0.011
camera type eye morphogenesis GO:0048593 108 0.011
blood vessel development GO:0001568 246 0.011
cellular response to biotic stimulus GO:0071216 3 0.011
cellular response to nutrient levels GO:0031669 2 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
sulfur compound metabolic process GO:0006790 13 0.011
release of sequestered calcium ion into cytosol GO:0051209 3 0.011
response to xenobiotic stimulus GO:0009410 45 0.011
cellular localization GO:0051641 97 0.011
hemopoiesis GO:0030097 183 0.010
muscle cell differentiation GO:0042692 139 0.010
regulation of cell death GO:0010941 103 0.010
cell aging GO:0007569 2 0.010
regulation of organelle organization GO:0033043 29 0.010
exocytosis GO:0006887 1 0.010
very long chain fatty acid metabolic process GO:0000038 4 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010
hatching GO:0035188 4 0.010
protein complex subunit organization GO:0071822 46 0.010
phosphorus metabolic process GO:0006793 109 0.010
cortical actin cytoskeleton organization GO:0030866 1 0.010
response to cold GO:0009409 4 0.010

pitpna disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.019
cancer DOID:162 0 0.017
disease of anatomical entity DOID:7 0 0.013
musculoskeletal system disease DOID:17 0 0.013
connective tissue disease DOID:65 0 0.013
nervous system disease DOID:863 0 0.012
disease of metabolism DOID:0014667 0 0.012