Danio rerio

106 known processes

pkd2

polycystic kidney disease 2

pkd2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
heart jogging GO:0003146 40 0.999
determination of bilateral symmetry GO:0009855 204 0.994
regulation of biological quality GO:0065008 263 0.993
Human Mouse
embryonic organ development GO:0048568 381 0.993
cilium organization GO:0044782 71 0.989
regulation of signaling GO:0023051 235 0.988
Human
cilium morphogenesis GO:0060271 85 0.987
specification of symmetry GO:0009799 204 0.983
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.981
Human Mouse
regulation of developmental process GO:0050793 247 0.980
determination of heart left right asymmetry GO:0061371 117 0.977
cellular component morphogenesis GO:0032989 336 0.976
regulation of metabolic process GO:0019222 359 0.976
negative regulation of biological process GO:0048519 304 0.969
Human Mouse
cell part morphogenesis GO:0032990 246 0.956
regulation of response to stimulus GO:0048583 269 0.952
Human
cellular component biogenesis GO:0044085 178 0.947
cell projection organization GO:0030030 284 0.943
determination of left right symmetry GO:0007368 179 0.941
cell morphogenesis GO:0000902 289 0.934
organelle organization GO:0006996 227 0.934
transport GO:0006810 220 0.933
Human Mouse Worm
regulation of multicellular organismal development GO:2000026 223 0.923
positive regulation of biological process GO:0048518 253 0.914
Human Mouse
heart development GO:0007507 313 0.906
heart morphogenesis GO:0003007 156 0.903
embryonic organ morphogenesis GO:0048562 274 0.897
cilium assembly GO:0042384 58 0.895
embryonic heart tube morphogenesis GO:0003143 108 0.895
single organism localization GO:1902578 225 0.893
Human Mouse Worm
cilium movement GO:0003341 26 0.892
positive regulation of response to stimulus GO:0048584 80 0.892
Human
heart looping GO:0001947 94 0.889
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.887
morphogenesis of an epithelium GO:0002009 333 0.883
convergent extension GO:0060026 118 0.881
regulation of transcription dna templated GO:0006355 213 0.880
Human
digestive system development GO:0055123 289 0.880
locomotion GO:0040011 313 0.879
developmental growth involved in morphogenesis GO:0060560 86 0.870
cell projection morphogenesis GO:0048858 244 0.859
single organism organelle organization GO:1902589 199 0.842
signal transduction GO:0007165 455 0.839
embryonic heart tube development GO:0035050 133 0.838
brain development GO:0007420 293 0.834
nucleic acid templated transcription GO:0097659 181 0.820
Human
epithelial cilium movement involved in determination of left right asymmetry GO:0060287 8 0.817
regulation of cell communication GO:0010646 232 0.804
Human
regulation of signal transduction GO:0009966 225 0.804
Human
establishment of localization GO:0051234 244 0.801
Human Mouse Worm
immune system process GO:0002376 241 0.801
organelle assembly GO:0070925 110 0.801
single organism transport GO:0044765 206 0.798
Human Mouse Worm
macromolecule localization GO:0033036 54 0.788
Human
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.785
cell motility GO:0048870 244 0.776
reproduction GO:0000003 40 0.769
Worm
nucleobase containing compound biosynthetic process GO:0034654 205 0.751
Human
negative regulation of cellular process GO:0048523 283 0.738
Human Mouse
gliogenesis GO:0042063 45 0.735
protein metabolic process GO:0019538 183 0.734
Human
cell death GO:0008219 121 0.726
single organism reproductive process GO:0044702 40 0.725
Mouse
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.715
heterocycle metabolic process GO:0046483 290 0.713
Human Mouse
positive regulation of cell communication GO:0010647 56 0.713
Human
tube morphogenesis GO:0035239 349 0.704
nucleobase containing compound metabolic process GO:0006139 274 0.703
Human Mouse
embryonic foregut morphogenesis GO:0048617 1 0.694
cellular component movement GO:0006928 335 0.665
protein localization GO:0008104 40 0.649
Human
establishment of localization in cell GO:0051649 77 0.644
Human Mouse
regulation of cellular component organization GO:0051128 86 0.642
homeostatic process GO:0042592 142 0.640
Human Mouse
cellular component assembly GO:0022607 170 0.628
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.623
Human
regulation of rna biosynthetic process GO:2001141 213 0.601
Human
cellular nitrogen compound metabolic process GO:0034641 290 0.599
Human Mouse
epithelial tube morphogenesis GO:0060562 148 0.583
cell growth GO:0016049 57 0.580
immune system development GO:0002520 191 0.558
gastrulation GO:0007369 208 0.543
digestive tract development GO:0048565 265 0.532
larval development GO:0002164 2 0.530
heterocycle biosynthetic process GO:0018130 215 0.530
Human
cellular nitrogen compound biosynthetic process GO:0044271 218 0.522
Human Mouse
growth GO:0040007 174 0.521
multicellular organism reproduction GO:0032504 35 0.520
Worm
ion transport GO:0006811 114 0.510
Human Mouse Worm
neural tube development GO:0021915 62 0.509
Human
neuron differentiation GO:0030182 353 0.503
organic substance transport GO:0071702 58 0.494
Human
negative regulation of metabolic process GO:0009892 86 0.474
organic cyclic compound metabolic process GO:1901360 301 0.473
Human Mouse
positive regulation of metabolic process GO:0009893 108 0.472
Human Mouse
multi organism process GO:0051704 134 0.456
Worm
regulation of nervous system development GO:0051960 90 0.446
connective tissue development GO:0061448 99 0.416
regulation of locomotion GO:0040012 55 0.407
positive regulation of cellular process GO:0048522 201 0.405
Human Mouse
cell migration GO:0016477 237 0.400
cellular macromolecule metabolic process GO:0044260 391 0.395
Human
negative regulation of gene expression GO:0010629 65 0.382
enzyme linked receptor protein signaling pathway GO:0007167 106 0.363
regulation of anatomical structure morphogenesis GO:0022603 130 0.354
pronephros development GO:0048793 69 0.353
negative regulation of developmental process GO:0051093 65 0.349
sensory organ development GO:0007423 393 0.337
regulation of embryonic development GO:0045995 47 0.337
cellular macromolecule biosynthetic process GO:0034645 224 0.334
Human
primary neural tube formation GO:0014020 1 0.332
transcription from rna polymerase ii promoter GO:0006366 80 0.322
Human
cellular component assembly involved in morphogenesis GO:0010927 107 0.320
mesenchyme development GO:0060485 127 0.320
Human
ameboidal type cell migration GO:0001667 143 0.316
macromolecular complex subunit organization GO:0043933 74 0.316
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.314
rna metabolic process GO:0016070 219 0.312
Human
regulation of rna metabolic process GO:0051252 224 0.311
Human
cell proliferation involved in heart morphogenesis GO:0061323 2 0.311
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.309
pericardium development GO:0060039 1 0.307
regulation of protein transport GO:0051223 3 0.307
Human
regulation of primary metabolic process GO:0080090 311 0.304
Human Mouse
neuron development GO:0048666 262 0.297
fin morphogenesis GO:0033334 53 0.295
negative regulation of apoptotic process GO:0043066 55 0.294
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.293
hemopoiesis GO:0030097 183 0.288
single organism cellular localization GO:1902580 46 0.287
Human
heart field specification GO:0003128 1 0.286
cell migration involved in heart development GO:0060973 22 0.284
regulation of multicellular organismal process GO:0051239 277 0.282
central nervous system development GO:0007417 387 0.281
Human
positive regulation of signaling GO:0023056 56 0.279
Human
kidney development GO:0001822 92 0.278
anterior posterior pattern specification GO:0009952 152 0.276
epithelial cell morphogenesis GO:0003382 2 0.274
transcription dna templated GO:0006351 181 0.273
Human
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.263
hematopoietic or lymphoid organ development GO:0048534 191 0.261
collagen metabolic process GO:0032963 2 0.259
death GO:0016265 121 0.256
cation transport GO:0006812 81 0.254
Human Mouse Worm
aromatic compound biosynthetic process GO:0019438 217 0.253
Human
stem cell maintenance GO:0019827 4 0.252
microtubule based movement GO:0007018 33 0.252
cilium movement involved in cell motility GO:0060294 3 0.250
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.250
system process GO:0003008 185 0.245
atrial ventricular junction remodeling GO:0003294 2 0.245
localization of cell GO:0051674 244 0.243
regulation of cell cycle GO:0051726 52 0.240
Human Mouse
wnt signaling pathway GO:0016055 80 0.238
inner ear development GO:0048839 126 0.237
developmental growth GO:0048589 166 0.237
tube closure GO:0060606 1 0.236
cation homeostasis GO:0055080 33 0.236
Human Mouse
heart formation GO:0060914 13 0.231
regulation of gene expression GO:0010468 265 0.230
Human Mouse
actin filament based process GO:0030029 64 0.227
reproductive process GO:0022414 40 0.218
Mouse Worm
regulation of macromolecule metabolic process GO:0060255 317 0.218
positive regulation of catabolic process GO:0009896 4 0.216
intermediate mesoderm development GO:0048389 2 0.216
gene expression GO:0010467 252 0.214
Human Mouse
aging GO:0007568 2 0.212
ear development GO:0043583 127 0.212
axoneme assembly GO:0035082 9 0.212
protein complex subunit organization GO:0071822 46 0.211
heart valve morphogenesis GO:0003179 8 0.207
nephron epithelium morphogenesis GO:0072088 1 0.206
Human
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.205
morphogenesis of an epithelial fold GO:0060571 1 0.203
cell surface receptor signaling pathway GO:0007166 325 0.203
outflow tract morphogenesis GO:0003151 1 0.203
positive regulation of transport GO:0051050 2 0.202
Human
response to chemical GO:0042221 320 0.202
Human
cellular localization GO:0051641 97 0.200
Human Mouse
pericardium morphogenesis GO:0003344 1 0.197
regulation of wnt signaling pathway involved in heart development GO:0003307 2 0.197
positive regulation of signal transduction GO:0009967 56 0.196
Human
regulation of programmed cell death GO:0043067 101 0.192
regulation of heart morphogenesis GO:2000826 17 0.187
regulation of cellular protein metabolic process GO:0032268 52 0.187
Human
neuron projection morphogenesis GO:0048812 161 0.185
foregut morphogenesis GO:0007440 4 0.183
embryonic skeletal joint development GO:0072498 3 0.182
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.182
steroid hormone mediated signaling pathway GO:0043401 9 0.180
response to biotic stimulus GO:0009607 97 0.179
renal system development GO:0072001 94 0.179
chordate embryonic development GO:0043009 271 0.177
Human Mouse
biosynthetic process GO:0009058 294 0.173
heart rudiment morphogenesis GO:0003314 6 0.172
metal ion transport GO:0030001 58 0.169
Human Mouse Worm
cilium or flagellum dependent cell motility GO:0001539 4 0.169
bmp signaling pathway involved in heart jogging GO:0003303 14 0.168
epithelial cilium movement GO:0003351 15 0.168
endocardial cell differentiation GO:0060956 5 0.166
mitotic nuclear division GO:0007067 18 0.165
cell cell adhesion involved in mesendodermal cell migration GO:0003370 1 0.163
response to stress GO:0006950 263 0.162
Human Mouse
cell morphogenesis involved in differentiation GO:0000904 195 0.160
epithelial tube formation GO:0072175 19 0.160
regionalization GO:0003002 274 0.158
rna biosynthetic process GO:0032774 181 0.158
Human
somite development GO:0061053 96 0.157
regulation of localization GO:0032879 104 0.157
Human Mouse
cardiac endothelial cell differentiation GO:0003348 5 0.157
cellular aromatic compound metabolic process GO:0006725 295 0.156
Human Mouse
response to external stimulus GO:0009605 264 0.156
Mouse
establishment of endothelial barrier GO:0061028 3 0.155
regulation of cell development GO:0060284 100 0.154
intracellular signal transduction GO:0035556 85 0.153
sexual reproduction GO:0019953 36 0.152
Worm
negative regulation of macromolecule metabolic process GO:0010605 76 0.150
positive regulation of cell adhesion GO:0045785 1 0.150
negative regulation of cell death GO:0060548 60 0.146
negative regulation of cell differentiation GO:0045596 46 0.145
digestive tract morphogenesis GO:0048546 231 0.145
regulation of axon extension GO:0030516 24 0.144
female sex differentiation GO:0046660 4 0.143
determination of liver left right asymmetry GO:0071910 11 0.141
Human
generation of neurons GO:0048699 385 0.140
regulation of cell death GO:0010941 103 0.136
mitotic cell cycle GO:0000278 64 0.135
Human
positive regulation of protein metabolic process GO:0051247 23 0.134
Human
regulation of cellular metabolic process GO:0031323 320 0.132
Human Mouse
urogenital system development GO:0001655 97 0.132
programmed cell death GO:0012501 119 0.132
cytoskeleton organization GO:0007010 96 0.131
epithelial cell differentiation GO:0030855 116 0.130
mitotic cell cycle process GO:1903047 48 0.130
Human
gall bladder development GO:0061010 1 0.126
positive regulation of catalytic activity GO:0043085 25 0.125
Human
positive regulation of molecular function GO:0044093 33 0.122
Human
nephron tubule morphogenesis GO:0072078 1 0.121
Human
regulation of cell projection organization GO:0031344 44 0.119
regulation of establishment of planar polarity GO:0090175 4 0.116
muscle cell differentiation GO:0042692 139 0.113
endoderm development GO:0007492 49 0.112
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.112
stem cell differentiation GO:0048863 117 0.111
macromolecular complex assembly GO:0065003 35 0.109
tube formation GO:0035148 25 0.108
positive regulation of neural precursor cell proliferation GO:2000179 1 0.107
head development GO:0060322 303 0.107
cell projection assembly GO:0030031 64 0.107
regulation of molecular function GO:0065009 70 0.106
Human Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.105
Human
regulation of organ morphogenesis GO:2000027 35 0.104
mesendoderm development GO:0048382 10 0.103
cell cycle process GO:0022402 53 0.102
Human Mouse
regulation of synapse assembly GO:0051963 3 0.102
anterior posterior axis specification GO:0009948 20 0.101
inner ear morphogenesis GO:0042472 63 0.100
negative regulation of programmed cell death GO:0043069 58 0.099
protein complex assembly GO:0006461 30 0.098
regulation of nucleic acid templated transcription GO:1903506 213 0.098
Human
cellular protein localization GO:0034613 20 0.097
Human
small gtpase mediated signal transduction GO:0007264 8 0.097
intracellular transport GO:0046907 32 0.096
Human Mouse
regulation of bone mineralization GO:0030500 2 0.096
embryonic epithelial tube formation GO:0001838 17 0.096
regulation of immune system process GO:0002682 34 0.095
response to bacterium GO:0009617 58 0.093
regulation of cell motility GO:2000145 46 0.093
semicircular canal morphogenesis GO:0048752 18 0.092
appendage morphogenesis GO:0035107 56 0.091
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.091
apoptotic process GO:0006915 116 0.091
humoral immune response mediated by circulating immunoglobulin GO:0002455 3 0.090
glomerulus vasculature development GO:0072012 2 0.090
retinal ganglion cell axon guidance GO:0031290 35 0.090
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.088
Human Mouse
embryonic digestive tract morphogenesis GO:0048557 3 0.088
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.088
nucleocytoplasmic transport GO:0006913 4 0.087
Human
eye morphogenesis GO:0048592 144 0.086
embryonic axis specification GO:0000578 12 0.085
single organism membrane organization GO:0044802 20 0.085
establishment or maintenance of monopolar cell polarity GO:0061339 2 0.084
striated muscle tissue development GO:0014706 110 0.084
muscle tissue development GO:0060537 110 0.084
Human
negative regulation of wnt signaling pathway involved in heart development GO:0003308 2 0.084
negative regulation of cellular metabolic process GO:0031324 77 0.083
calcium ion import GO:0070509 4 0.081
Human
positive regulation of striated muscle tissue development GO:0045844 1 0.081
establishment of apical basal cell polarity GO:0035089 2 0.081
negative regulation of response to stimulus GO:0048585 104 0.081
skeletal system morphogenesis GO:0048705 102 0.079
cellular macromolecule localization GO:0070727 21 0.079
Human
cell migration involved in gastrulation GO:0042074 79 0.079
negative regulation of growth GO:0045926 10 0.079
cellular component disassembly GO:0022411 1 0.078
regulation of growth GO:0040008 42 0.076
regulation of muscle tissue development GO:1901861 6 0.076
blood vessel morphogenesis GO:0048514 216 0.076
Human
anterior head development GO:0097065 2 0.076
positive regulation of cellular protein metabolic process GO:0032270 22 0.076
Human
protein complex biogenesis GO:0070271 30 0.076
homeostasis of number of cells GO:0048872 62 0.075
regulation of skeletal muscle tissue development GO:0048641 4 0.075
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.073
Human
embryo development ending in birth or egg hatching GO:0009792 271 0.073
Human Mouse
unidimensional cell growth GO:0009826 5 0.073
striated muscle cell differentiation GO:0051146 129 0.073
phosphate containing compound metabolic process GO:0006796 108 0.072
Human Mouse
organic substance biosynthetic process GO:1901576 289 0.071
positive regulation of cell cycle GO:0045787 3 0.071
Human
cellular ion homeostasis GO:0006873 17 0.071
Human Mouse
regulation of apoptotic process GO:0042981 98 0.071
regulation of biosynthetic process GO:0009889 250 0.070
regulation of protein targeting GO:1903533 2 0.070
Human
positive regulation of muscle organ development GO:0048636 1 0.070
regulation of cell morphogenesis GO:0022604 42 0.069
atrioventricular valve formation GO:0003190 3 0.068
regulation of chondrocyte differentiation GO:0032330 1 0.068
negative regulation of biosynthetic process GO:0009890 55 0.067
nucleic acid metabolic process GO:0090304 244 0.066
Human
multicellular organismal reproductive process GO:0048609 35 0.066
Worm
membrane organization GO:0061024 21 0.066
negative regulation of rna metabolic process GO:0051253 48 0.066
catabolic process GO:0009056 32 0.065
regulation of multicellular organism growth GO:0040014 4 0.065
sensory organ morphogenesis GO:0090596 200 0.065
neurological system process GO:0050877 62 0.064
stem cell division GO:0017145 1 0.064
regulation of cellular component movement GO:0051270 55 0.064
epithelial to mesenchymal transition GO:0001837 21 0.064
regulation of stem cell proliferation GO:0072091 2 0.063
positive regulation of macromolecule metabolic process GO:0010604 93 0.062
Human Mouse
negative regulation of muscle tissue development GO:1901862 2 0.062
cardiocyte differentiation GO:0035051 44 0.062
establishment or maintenance of cell polarity GO:0007163 29 0.062
endocardium morphogenesis GO:0003160 4 0.062
regulation of organelle organization GO:0033043 29 0.061
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.061
Human
regulation of catalytic activity GO:0050790 55 0.060
Human
response to abiotic stimulus GO:0009628 122 0.060
Human Mouse
wnt signaling pathway involved in heart development GO:0003306 5 0.059
rho protein signal transduction GO:0007266 5 0.059
axis elongation GO:0003401 31 0.058
negative regulation of cellular component organization GO:0051129 16 0.058
cell fate commitment GO:0045165 99 0.058
axial mesoderm formation GO:0048320 4 0.057
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.057
regulation of nitrogen compound metabolic process GO:0051171 251 0.056
Human Mouse
cartilage morphogenesis GO:0060536 13 0.056
optic placode formation GO:0001743 4 0.056
regulation of binding GO:0051098 3 0.056
regulation of intracellular signal transduction GO:1902531 57 0.056
Human
establishment of organelle localization GO:0051656 45 0.056
positive regulation of skeletal muscle tissue development GO:0048643 1 0.055
regulation of cell differentiation GO:0045595 142 0.055
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.055
cell proliferation GO:0008283 80 0.055
Human
ear morphogenesis GO:0042471 64 0.054
ion homeostasis GO:0050801 41 0.053
Human Mouse
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.053
skin development GO:0043588 54 0.053
homeostasis of number of cells within a tissue GO:0048873 4 0.053
biological adhesion GO:0022610 40 0.053
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.052
Human
endochondral bone morphogenesis GO:0060350 8 0.052
regulation of protein catabolic process GO:0042176 1 0.052
establishment of protein localization to plasma membrane GO:0090002 1 0.051
blood vessel development GO:0001568 246 0.051
Human Mouse
regulation of establishment of protein localization GO:0070201 4 0.051
Human
neuron projection extension GO:1990138 45 0.050
wnt signaling pathway involved in somitogenesis GO:0090244 2 0.050
retinal cone cell development GO:0046549 8 0.050
response to fluid shear stress GO:0034405 2 0.050
Human Mouse
cardioblast migration to the midline involved in heart rudiment formation GO:0003319 5 0.050
multicellular organism growth GO:0035264 4 0.049
cell adhesion GO:0007155 40 0.049
chemotaxis GO:0006935 104 0.049
taxis GO:0042330 109 0.048
regulation of cell migration GO:0030334 40 0.048
semicircular canal development GO:0060872 24 0.048
keratinocyte differentiation GO:0030216 0 0.047
regulation of reproductive process GO:2000241 4 0.047
gamete generation GO:0007276 33 0.047
regulation of cell proliferation GO:0042127 37 0.046
Human
establishment of monopolar cell polarity GO:0061162 2 0.046
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.046
positive regulation of nucleic acid templated transcription GO:1903508 57 0.046
Human
behavior GO:0007610 74 0.045
Worm
positive regulation of cellular metabolic process GO:0031325 94 0.044
Human Mouse
cognition GO:0050890 1 0.044
negative regulation of striated muscle tissue development GO:0045843 2 0.044
response to other organism GO:0051707 97 0.044
negative regulation of chemotaxis GO:0050922 4 0.044
regulation of muscle organ development GO:0048634 9 0.043
positive regulation of ras protein signal transduction GO:0046579 1 0.043
mesenchymal cell development GO:0014031 78 0.043
notochord cell differentiation GO:0060034 18 0.041
response to external biotic stimulus GO:0043207 97 0.041
cell cell adhesion mediated by cadherin GO:0044331 5 0.041
axonogenesis GO:0007409 152 0.041
neuron projection development GO:0031175 180 0.041
hard palate development GO:0060022 4 0.041
negative regulation of axon extension involved in axon guidance GO:0048843 1 0.041
multi organism reproductive process GO:0044703 36 0.041
Worm
regulation of axonogenesis GO:0050770 32 0.040
bone development GO:0060348 14 0.040
myeloid cell homeostasis GO:0002262 56 0.040
negative regulation of wnt signaling pathway GO:0030178 30 0.040
ras protein signal transduction GO:0007265 7 0.039
organonitrogen compound metabolic process GO:1901564 74 0.039
Mouse
muscle structure development GO:0061061 196 0.039
astrocyte differentiation GO:0048708 1 0.039
hepaticobiliary system development GO:0061008 98 0.039
Human Mouse
regulation of stem cell differentiation GO:2000736 4 0.038
proteolysis GO:0006508 38 0.038
bmp signaling pathway GO:0030509 52 0.038
neural crest cell migration GO:0001755 42 0.038
immune response GO:0006955 28 0.038
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.038
calcium ion homeostasis GO:0055074 19 0.037
Human Mouse
negative regulation of transcription dna templated GO:0045892 45 0.037
carbohydrate derivative biosynthetic process GO:1901137 43 0.037
regulation of behavior GO:0050795 24 0.037
heart valve development GO:0003170 14 0.037
regulation of nucleocytoplasmic transport GO:0046822 2 0.036
Human
positive regulation of nervous system development GO:0051962 25 0.036
biomineral tissue development GO:0031214 13 0.036
meiotic cell cycle process GO:1903046 3 0.036
regulation of tube size GO:0035150 2 0.036
establishment of mitotic spindle localization GO:0040001 12 0.036
positive regulation of cell development GO:0010720 25 0.036
heart rudiment development GO:0003313 8 0.035
establishment of cell polarity GO:0030010 18 0.035
fin regeneration GO:0031101 51 0.035
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.035
embryonic skeletal joint morphogenesis GO:0060272 3 0.035
establishment of protein localization to organelle GO:0072594 4 0.035
Human
specification of axis polarity GO:0065001 4 0.035
stem cell development GO:0048864 82 0.034
positive regulation of cell proliferation GO:0008284 15 0.034
axon extension GO:0048675 45 0.034
positive regulation of stress activated mapk cascade GO:0032874 3 0.034
left right pattern formation GO:0060972 19 0.033
cellular cation homeostasis GO:0030003 17 0.033
Human Mouse
germ line stem cell maintenance GO:0030718 2 0.033
purine nucleotide metabolic process GO:0006163 27 0.033
Mouse
positive regulation of stem cell proliferation GO:2000648 1 0.033
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.033
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.033
positive regulation of jun kinase activity GO:0043507 2 0.032
regulation of mitotic cell cycle GO:0007346 25 0.032
Human
mononuclear cell proliferation GO:0032943 1 0.032
regulation of neuron projection development GO:0010975 40 0.032
positive regulation of gastrulation GO:2000543 2 0.032
regulation of cell cell adhesion GO:0022407 13 0.032
microtubule bundle formation GO:0001578 9 0.032
stem cell proliferation GO:0072089 4 0.032
actin cytoskeleton organization GO:0030036 63 0.032
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.031
atrioventricular valve development GO:0003171 11 0.031
negative regulation of cell proliferation GO:0008285 8 0.031
regulation of proteolysis GO:0030162 24 0.031
inner ear receptor stereocilium organization GO:0060122 8 0.031
microtubule based process GO:0007017 60 0.031
regulation of biomineral tissue development GO:0070167 2 0.031
b cell mediated immunity GO:0019724 3 0.031
response to organic cyclic compound GO:0014070 51 0.031
response to alkaloid GO:0043279 2 0.030
regulation of dendrite development GO:0050773 3 0.030
neural tube formation GO:0001841 16 0.030
cardiac cell fate commitment GO:0060911 1 0.030
fin development GO:0033333 77 0.030
cellular biosynthetic process GO:0044249 286 0.030
Human Mouse
regulation of wnt signaling pathway GO:0030111 53 0.030
cellular carbohydrate metabolic process GO:0044262 4 0.030
wnt signaling pathway planar cell polarity pathway GO:0060071 4 0.029
immunoglobulin mediated immune response GO:0016064 3 0.029
modification dependent macromolecule catabolic process GO:0043632 3 0.029
embryonic pattern specification GO:0009880 44 0.029
hatching GO:0035188 4 0.029
somatic stem cell maintenance GO:0035019 1 0.029
cell substrate adhesion GO:0031589 4 0.029
organelle localization GO:0051640 49 0.028
negative regulation of rna biosynthetic process GO:1902679 45 0.028
regulation of microtubule based movement GO:0060632 3 0.028
nephron tubule epithelial cell differentiation GO:0072160 1 0.028
defense response to fungus GO:0050832 2 0.028
intestinal epithelial cell differentiation GO:0060575 3 0.028
hormone biosynthetic process GO:0042446 3 0.028
optic placode formation involved in camera type eye formation GO:0046619 3 0.027
organelle fission GO:0048285 23 0.027

pkd2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.066
disease of cellular proliferation DOID:14566 0 0.066
organ system cancer DOID:0050686 0 0.066
disease of anatomical entity DOID:7 0 0.059