Danio rerio

0 known processes

pkm2a

pyruvate kinase, muscle, a

(Aliases: cb1029,pkm2,wu:fj33f03,fj33f03)

pkm2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
pyruvate metabolic process GO:0006090 1 0.723
Yeast Mouse Rat
carbohydrate metabolic process GO:0005975 12 0.479
Yeast Mouse Rat
nitrogen compound metabolic process GO:0006807 319 0.344
Rat
regulation of transmembrane transporter activity GO:0022898 2 0.321
aging GO:0007568 2 0.315
Worm
ribose phosphate biosynthetic process GO:0046390 20 0.301
Rat
regulation of metabolic process GO:0019222 359 0.289
cellular aromatic compound metabolic process GO:0006725 295 0.249
Rat
nucleobase containing small molecule metabolic process GO:0055086 32 0.222
Rat
single organism carbohydrate metabolic process GO:0044723 12 0.217
Yeast Mouse Rat
organelle fusion GO:0048284 3 0.215
response to stress GO:0006950 263 0.196
Rat
larval development GO:0002164 2 0.181
Worm
negative regulation of biological process GO:0048519 304 0.174
heterocycle metabolic process GO:0046483 290 0.174
Rat
regulation of metal ion transport GO:0010959 4 0.164
single organism transport GO:0044765 206 0.163
regulation of macromolecule metabolic process GO:0060255 317 0.161
brain development GO:0007420 293 0.155
carbohydrate biosynthetic process GO:0016051 1 0.154
regionalization GO:0003002 274 0.149
muscle structure development GO:0061061 196 0.146
Worm
muscle cell differentiation GO:0042692 139 0.141
Worm
maintenance of location GO:0051235 4 0.141
regulation of circadian rhythm GO:0042752 4 0.138
cellular nitrogen compound metabolic process GO:0034641 290 0.137
Rat
regulation of muscle contraction GO:0006937 3 0.133
regulation of sodium ion transmembrane transport GO:1902305 1 0.132
oocyte anterior posterior axis specification GO:0007314 4 0.131
organic acid metabolic process GO:0006082 31 0.129
Yeast Mouse Rat
growth GO:0040007 174 0.127
Rat
peptidyl serine phosphorylation GO:0018105 1 0.125
nucleic acid metabolic process GO:0090304 244 0.124
regulation of multicellular organism growth GO:0040014 4 0.123
single organism metabolic process GO:0044710 217 0.122
Yeast Mouse Rat
inorganic cation transmembrane transport GO:0098662 50 0.121
transmembrane transport GO:0055085 120 0.121
circadian sleep wake cycle GO:0042745 2 0.121
sodium ion transmembrane transport GO:0035725 21 0.117
inorganic ion transmembrane transport GO:0098660 57 0.114
small molecule metabolic process GO:0044281 77 0.113
Yeast Mouse Rat
carboxylic acid metabolic process GO:0019752 22 0.113
Yeast Mouse Rat
cation transmembrane transport GO:0098655 65 0.112
regulation of multicellular organismal process GO:0051239 277 0.108
ion transmembrane transport GO:0034220 91 0.103
oxoacid metabolic process GO:0043436 31 0.101
Yeast Mouse Rat
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.095
metal ion transport GO:0030001 58 0.094
cell cycle g2 m phase transition GO:0044839 4 0.093
cellular macromolecule metabolic process GO:0044260 391 0.092
single fertilization GO:0007338 3 0.092
adult behavior GO:0030534 2 0.092
regulation of developmental process GO:0050793 247 0.091
phosphorus metabolic process GO:0006793 109 0.091
Yeast Mouse Rat
carbohydrate derivative biosynthetic process GO:1901137 43 0.091
Rat
localization of cell GO:0051674 244 0.088
negative regulation of cellular process GO:0048523 283 0.086
regulation of cellular component organization GO:0051128 86 0.086
neural nucleus development GO:0048857 15 0.085
organic cyclic compound metabolic process GO:1901360 301 0.085
Rat
organism emergence from protective structure GO:0071684 4 0.084
developmental growth GO:0048589 166 0.083
Rat
membrane fusion GO:0061025 2 0.080
regulation of transporter activity GO:0032409 2 0.079
carbohydrate derivative metabolic process GO:1901135 61 0.079
Rat
regulation of striated muscle contraction GO:0006942 2 0.078
biosynthetic process GO:0009058 294 0.075
Rat
central nervous system development GO:0007417 387 0.075
single organism membrane fusion GO:0044801 2 0.072
cellular biosynthetic process GO:0044249 286 0.070
Rat
aromatic compound biosynthetic process GO:0019438 217 0.070
Rat
sleep GO:0030431 1 0.070
nucleobase containing compound metabolic process GO:0006139 274 0.068
Rat
regulation of primary metabolic process GO:0080090 311 0.067
cell aging GO:0007569 2 0.066
cellular component morphogenesis GO:0032989 336 0.066
Worm
cell surface receptor signaling pathway GO:0007166 325 0.065
cellular response to external stimulus GO:0071496 2 0.062
organelle organization GO:0006996 227 0.061
Worm
response to external stimulus GO:0009605 264 0.061
Rat
cellular response to extracellular stimulus GO:0031668 2 0.061
cell projection morphogenesis GO:0048858 244 0.060
peptidyl serine modification GO:0018209 2 0.059
multicellular organism growth GO:0035264 4 0.059
positive regulation of transport GO:0051050 2 0.058
response to amphetamine GO:0001975 1 0.058
energy reserve metabolic process GO:0006112 2 0.057
regulation of cellular biosynthetic process GO:0031326 245 0.057
gene expression GO:0010467 252 0.056
morphogenesis of an epithelium GO:0002009 333 0.056
regulation of ion transmembrane transporter activity GO:0032412 2 0.055
generation of neurons GO:0048699 385 0.055
regulation of intracellular ph GO:0051453 1 0.054
organic substance biosynthetic process GO:1901576 289 0.054
Rat
transport GO:0006810 220 0.054
striated muscle cell differentiation GO:0051146 129 0.051
Worm
synaptic vesicle recycling GO:0036465 1 0.051
regulation of response to stimulus GO:0048583 269 0.050
regulation of ion transmembrane transport GO:0034765 18 0.050
sequestering of calcium ion GO:0051208 3 0.050
regulation of receptor activity GO:0010469 2 0.050
macromolecule biosynthetic process GO:0009059 227 0.049
homeostatic process GO:0042592 142 0.049
heterocycle biosynthetic process GO:0018130 215 0.049
Rat
organic cyclic compound biosynthetic process GO:1901362 223 0.049
Rat
nucleic acid templated transcription GO:0097659 181 0.048
programmed cell death GO:0012501 119 0.047
Human
cortical actin cytoskeleton organization GO:0030866 1 0.047
regulation of cardiac muscle contraction GO:0055117 2 0.047
system process GO:0003008 185 0.047
anterior posterior pattern specification GO:0009952 152 0.046
myoblast fusion GO:0007520 10 0.046
neuron projection development GO:0031175 180 0.046
cellular amino acid metabolic process GO:0006520 7 0.046
transcription dna templated GO:0006351 181 0.046
single organism organelle organization GO:1902589 199 0.045
Worm
cellular nitrogen compound biosynthetic process GO:0044271 218 0.045
Rat
regulation of ph GO:0006885 3 0.044
regulation of cell shape GO:0008360 1 0.044
positive regulation of biological process GO:0048518 253 0.044
positive regulation of cellular metabolic process GO:0031325 94 0.044
maternal determination of anterior posterior axis embryo GO:0008358 4 0.043
cellular carbohydrate metabolic process GO:0044262 4 0.043
embryo development ending in birth or egg hatching GO:0009792 271 0.042
Worm
negative regulation of cell growth GO:0030308 7 0.041
negative regulation of macromolecule metabolic process GO:0010605 76 0.041
rna metabolic process GO:0016070 219 0.041
hatching GO:0035188 4 0.040
somatic muscle development GO:0007525 4 0.040
meiotic chromosome segregation GO:0045132 3 0.040
g protein coupled receptor signaling pathway GO:0007186 74 0.040
regulation of rna metabolic process GO:0051252 224 0.040
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.039
rna biosynthetic process GO:0032774 181 0.039
regulation of binding GO:0051098 3 0.039
head development GO:0060322 303 0.038
regulation of erk1 and erk2 cascade GO:0070372 4 0.038
g2 m transition of mitotic cell cycle GO:0000086 4 0.038
regulation of reproductive process GO:2000241 4 0.038
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.038
embryonic organ morphogenesis GO:0048562 274 0.037
meiotic cell cycle process GO:1903046 3 0.037
cytoplasm organization GO:0007028 4 0.037
establishment of localization GO:0051234 244 0.037
single organism localization GO:1902578 225 0.036
pole plasm assembly GO:0007315 4 0.036
regulation of cell growth GO:0001558 29 0.036
signal transduction GO:0007165 455 0.035
protein dephosphorylation GO:0006470 3 0.035
ion transport GO:0006811 114 0.035
regulation of protein metabolic process GO:0051246 56 0.035
cell morphogenesis involved in differentiation GO:0000904 195 0.035
synaptic growth at neuromuscular junction GO:0051124 2 0.035
metal ion homeostasis GO:0055065 26 0.034
heart development GO:0007507 313 0.034
regulation of cellular amine metabolic process GO:0033238 0 0.034
stem cell proliferation GO:0072089 4 0.034
response to oxygen levels GO:0070482 25 0.033
Rat
protein polymerization GO:0051258 4 0.033
blood coagulation GO:0007596 12 0.033
cell growth GO:0016049 57 0.032
regulation of molecular function GO:0065009 70 0.032
regulation of circadian sleep wake cycle GO:0042749 1 0.032
regulation of sodium ion transport GO:0002028 2 0.032
regulation of cytoplasmic transport GO:1903649 4 0.032
negative regulation of blood circulation GO:1903523 2 0.032
microtubule based process GO:0007017 60 0.032
actin filament based process GO:0030029 64 0.031
Worm
striated muscle contraction GO:0006941 12 0.031
purine nucleoside monophosphate catabolic process GO:0009128 4 0.031
guanosine containing compound catabolic process GO:1901069 2 0.031
embryonic heart tube morphogenesis GO:0003143 108 0.031
regulation of gene expression GO:0010468 265 0.031
neuron projection morphogenesis GO:0048812 161 0.031
negative regulation of metabolic process GO:0009892 86 0.031
positive regulation of cellular catabolic process GO:0031331 3 0.031
cation transport GO:0006812 81 0.030
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.030
regulation of cellular amino acid metabolic process GO:0006521 0 0.030
negative regulation of gene expression GO:0010629 65 0.030
female sex differentiation GO:0046660 4 0.030
regulation of establishment of protein localization GO:0070201 4 0.030
regulation of biological quality GO:0065008 263 0.030
cellular protein complex assembly GO:0043623 19 0.030
Worm
phagocytosis GO:0006909 3 0.030
lipid storage GO:0019915 1 0.030
protein metabolic process GO:0019538 183 0.029
atp catabolic process GO:0006200 4 0.029
positive regulation of catabolic process GO:0009896 4 0.028
regulation of transcription dna templated GO:0006355 213 0.028
response to ketone GO:1901654 1 0.028
fertilization GO:0009566 3 0.028
circadian sleep wake cycle sleep GO:0050802 1 0.028
regulation of protein catabolic process GO:0042176 1 0.027
regulation of protein targeting GO:1903533 2 0.027
circadian sleep wake cycle process GO:0022410 2 0.027
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.027
ribonucleoside monophosphate catabolic process GO:0009158 4 0.027
chordate embryonic development GO:0043009 271 0.027
entrainment of circadian clock GO:0009649 2 0.027
negative regulation of biosynthetic process GO:0009890 55 0.027
regulation of meiotic cell cycle GO:0051445 1 0.027
gtp catabolic process GO:0006184 2 0.026
cell motility GO:0048870 244 0.026
dicarboxylic acid metabolic process GO:0043648 1 0.026
axon development GO:0061564 166 0.026
axonogenesis GO:0007409 152 0.026
cyclic purine nucleotide metabolic process GO:0052652 18 0.026
regulation of protein ubiquitination GO:0031396 3 0.026
striated muscle myosin thick filament assembly GO:0071688 6 0.026
Worm
muscle cell development GO:0055001 115 0.026
Worm
gtp metabolic process GO:0046039 4 0.026
regulation of protein transport GO:0051223 3 0.026
catabolic process GO:0009056 32 0.026
Yeast Mouse Rat
cellular response to nutrient levels GO:0031669 2 0.026
negative regulation of sequestering of calcium ion GO:0051283 4 0.026
ubiquitin dependent protein catabolic process GO:0006511 3 0.025
membrane hyperpolarization GO:0060081 1 0.025
exocytosis GO:0006887 1 0.025
cell substrate adhesion GO:0031589 4 0.025
cell fate specification GO:0001708 68 0.024
single organism biosynthetic process GO:0044711 71 0.024
Rat
amine metabolic process GO:0009308 2 0.024
homologous chromosome segregation GO:0045143 1 0.024
cellular amine metabolic process GO:0044106 2 0.024
regulation of localization GO:0032879 104 0.024
single organism nuclear import GO:1902593 3 0.024
macromolecule modification GO:0043412 111 0.024
regulation of cellular ph GO:0030641 1 0.024
response to biotic stimulus GO:0009607 97 0.023
response to copper ion GO:0046688 13 0.023
sequestering of metal ion GO:0051238 3 0.023
regulation of nucleic acid templated transcription GO:1903506 213 0.023
neuron differentiation GO:0030182 353 0.023
cell morphogenesis GO:0000902 289 0.023
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.023
cellular component biogenesis GO:0044085 178 0.023
Worm
pronuclear migration GO:0035046 1 0.023
protein localization to plasma membrane GO:0072659 1 0.023
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.022
intracellular mrna localization GO:0008298 1 0.022
protein stabilization GO:0050821 2 0.022
cellular component assembly GO:0022607 170 0.022
Worm
purine containing compound biosynthetic process GO:0072522 20 0.022
Rat
regulation of cell activation GO:0050865 1 0.022
response to amine GO:0014075 1 0.022
meiotic nuclear division GO:0007126 4 0.022
heart looping GO:0001947 94 0.022
vasculature development GO:0001944 278 0.022
organonitrogen compound metabolic process GO:1901564 74 0.022
Rat
wound healing GO:0042060 90 0.022
Rat
cellular macromolecule biosynthetic process GO:0034645 224 0.021
regulation of cellular metabolic process GO:0031323 320 0.021
regulation of anatomical structure morphogenesis GO:0022603 130 0.021
phagocytosis engulfment GO:0006911 1 0.021
syncytium formation by plasma membrane fusion GO:0000768 12 0.021
neurotransmitter transport GO:0006836 2 0.021
calcium ion transport into cytosol GO:0060402 3 0.021
determination of left right symmetry GO:0007368 179 0.021
locomotion GO:0040011 313 0.021
extracellular structure organization GO:0043062 27 0.021
organic substance catabolic process GO:1901575 28 0.021
Yeast Mouse Rat
embryonic heart tube development GO:0035050 133 0.020
hormone transport GO:0009914 2 0.020
negative regulation of secretion GO:0051048 2 0.020
centrosome cycle GO:0007098 1 0.020
striated muscle cell development GO:0055002 108 0.020
Worm
protein targeting to nucleus GO:0044744 3 0.020
regulation of transmembrane transport GO:0034762 18 0.020
organophosphate biosynthetic process GO:0090407 23 0.020
Rat
response to hypoxia GO:0001666 25 0.020
Rat
regulation of sodium ion transmembrane transporter activity GO:2000649 1 0.020
steroid hormone secretion GO:0035929 1 0.020
nuclear import GO:0051170 3 0.020
purine ribonucleotide metabolic process GO:0009150 27 0.020
Rat
regulation of biosynthetic process GO:0009889 250 0.020
cell part morphogenesis GO:0032990 246 0.019
sensory organ development GO:0007423 393 0.019
membrane invagination GO:0010324 1 0.019
axon cargo transport GO:0008088 2 0.019
synaptic vesicle transport GO:0048489 1 0.019
cellular component assembly involved in morphogenesis GO:0010927 107 0.019
Worm
phosphate containing compound metabolic process GO:0006796 108 0.019
Yeast Mouse Rat
mitotic cell cycle GO:0000278 64 0.019
release of sequestered calcium ion into cytosol GO:0051209 3 0.019
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.019
synaptic vesicle localization GO:0097479 1 0.019
regulation of nucleocytoplasmic transport GO:0046822 2 0.019
positive regulation of metabolic process GO:0009893 108 0.019
membrane repolarization GO:0086009 2 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.018
protein import GO:0017038 3 0.018
midbrain development GO:0030901 28 0.018
guanosine containing compound metabolic process GO:1901068 4 0.018
regulation of developmental growth GO:0048638 38 0.018
embryonic organ development GO:0048568 381 0.018
cytoskeleton organization GO:0007010 96 0.018
Worm
cellular macromolecular complex assembly GO:0034622 24 0.018
Worm
modification dependent protein catabolic process GO:0019941 3 0.018
response to other organism GO:0051707 97 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.018
cellular potassium ion transport GO:0071804 10 0.018
myotube differentiation GO:0014902 45 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.018
oxidation reduction process GO:0055114 41 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
regulation of nucleoside metabolic process GO:0009118 2 0.017
nucleoside monophosphate catabolic process GO:0009125 4 0.017
regulation of calcium ion transport GO:0051924 2 0.017
anion transport GO:0006820 38 0.017
nucleoside monophosphate biosynthetic process GO:0009124 1 0.017
Rat
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.017
protein localization to nucleus GO:0034504 3 0.017
tube morphogenesis GO:0035239 349 0.017
cardiac conduction GO:0061337 3 0.017
monocarboxylic acid metabolic process GO:0032787 17 0.017
Yeast Mouse Rat
rna localization GO:0006403 4 0.016
regulation of signaling GO:0023051 235 0.016
cellular component movement GO:0006928 335 0.016
calcium ion transport GO:0006816 18 0.016
embryonic skeletal joint development GO:0072498 3 0.016
response to external biotic stimulus GO:0043207 97 0.016
endocrine process GO:0050886 2 0.016
regulation of neurogenesis GO:0050767 87 0.016
cytosolic calcium ion transport GO:0060401 3 0.016
negative regulation of rna metabolic process GO:0051253 48 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
response to abiotic stimulus GO:0009628 122 0.016
Rat
regulation of cell development GO:0060284 100 0.016
positive regulation of map kinase activity GO:0043406 3 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
regulation of synapse organization GO:0050807 3 0.015
monovalent inorganic cation transport GO:0015672 42 0.015
axis specification GO:0009798 43 0.015
regulation of cell differentiation GO:0045595 142 0.015
positive regulation of cellular component biogenesis GO:0044089 3 0.015
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.015
nuclear transport GO:0051169 4 0.015
regulation of multicellular organismal development GO:2000026 223 0.015
cytokinesis GO:0000910 3 0.015
sensory organ morphogenesis GO:0090596 200 0.015
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.015
syncytium formation GO:0006949 12 0.015
erk1 and erk2 cascade GO:0070371 4 0.015
regulation of system process GO:0044057 40 0.015
nucleocytoplasmic transport GO:0006913 4 0.015
cellular protein metabolic process GO:0044267 129 0.015
modification dependent macromolecule catabolic process GO:0043632 3 0.015
organophosphate metabolic process GO:0019637 37 0.015
Rat
protein secretion GO:0009306 1 0.015
synaptic vesicle endocytosis GO:0048488 1 0.014
angiogenesis GO:0001525 158 0.014
establishment of protein localization to organelle GO:0072594 4 0.014
response to alkaloid GO:0043279 2 0.014
apoptotic process GO:0006915 116 0.014
axon ensheathment in central nervous system GO:0032291 2 0.014
regulation of cell communication GO:0010646 232 0.014
regulation of sequestering of calcium ion GO:0051282 4 0.014
neurological system process GO:0050877 62 0.014
positive regulation of blood circulation GO:1903524 2 0.014
regulation of neurotransmitter secretion GO:0046928 1 0.014
regulation of cell death GO:0010941 103 0.014
negative regulation of cellular catabolic process GO:0031330 3 0.014
regulation of nucleotide catabolic process GO:0030811 2 0.014
negative regulation of response to stimulus GO:0048585 104 0.014
cytokinetic process GO:0032506 2 0.014
cell projection organization GO:0030030 284 0.014
glutamate receptor signaling pathway GO:0007215 1 0.014
microtubule organizing center organization GO:0031023 1 0.014
death GO:0016265 121 0.014
Human
organelle assembly GO:0070925 110 0.014
Worm
blood circulation GO:0008015 87 0.014
establishment of protein localization to plasma membrane GO:0090002 1 0.014
regulation of synapse assembly GO:0051963 3 0.014
negative regulation of secretion by cell GO:1903531 2 0.014
cellular cation homeostasis GO:0030003 17 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
cortical cytoskeleton organization GO:0030865 1 0.013
blood vessel development GO:0001568 246 0.013
collagen metabolic process GO:0032963 2 0.013
actin polymerization or depolymerization GO:0008154 2 0.013
cellular amide metabolic process GO:0043603 4 0.013
compound eye development GO:0048749 2 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.013
heart morphogenesis GO:0003007 156 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.013
specification of axis polarity GO:0065001 4 0.013
lateral line development GO:0048882 66 0.013
negative regulation of cellular biosynthetic process GO:0031327 55 0.013
nucleoside phosphate biosynthetic process GO:1901293 21 0.013
Rat
establishment of synaptic vesicle localization GO:0097480 1 0.013
regulation of neurotransmitter transport GO:0051588 1 0.013
nuclear migration GO:0007097 3 0.013
eye development GO:0001654 277 0.013
regulation of transport GO:0051049 45 0.013
ribose phosphate metabolic process GO:0019693 27 0.013
Rat
cell migration involved in heart development GO:0060973 22 0.013
vacuole organization GO:0007033 9 0.013
regulation of hormone secretion GO:0046883 2 0.013
regulation of blood pressure GO:0008217 1 0.013
er to golgi vesicle mediated transport GO:0006888 1 0.013
nuclear export GO:0051168 1 0.013
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
Rat
regulation of phosphate metabolic process GO:0019220 43 0.012
regulation of synaptic vesicle transport GO:1902803 1 0.012
response to drug GO:0042493 3 0.012
cation homeostasis GO:0055080 33 0.012
endomembrane system organization GO:0010256 13 0.012
dicarboxylic acid transport GO:0006835 1 0.012
epithelial tube morphogenesis GO:0060562 148 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.012
positive regulation of molecular function GO:0044093 33 0.012
locomotory behavior GO:0007626 34 0.012
positive regulation of cell division GO:0051781 2 0.012
rna 3 end processing GO:0031123 2 0.012
dorsal ventral pattern formation GO:0009953 125 0.012
embryonic skeletal joint morphogenesis GO:0060272 3 0.012
neuromuscular process controlling balance GO:0050885 3 0.012
positive regulation of biosynthetic process GO:0009891 68 0.012
negative regulation of nucleic acid templated transcription GO:1903507 45 0.012
collateral sprouting in absence of injury GO:0048669 4 0.012
organ regeneration GO:0031100 1 0.012
Rat
cellular aldehyde metabolic process GO:0006081 4 0.012
regulation of signal transduction GO:0009966 225 0.012
positive regulation of cell cycle GO:0045787 3 0.012
response to corticosteroid GO:0031960 1 0.012
ribosomal small subunit biogenesis GO:0042274 2 0.012
cellular protein modification process GO:0006464 100 0.012
spermatid differentiation GO:0048515 2 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.012
centrosome organization GO:0051297 1 0.012
regulation of cyclic nucleotide biosynthetic process GO:0030802 15 0.012
nucleotide biosynthetic process GO:0009165 21 0.012
Rat
camera type eye morphogenesis GO:0048593 108 0.012
regulation of nitrogen compound metabolic process GO:0051171 251 0.012
pigmentation GO:0043473 85 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
response to chemical GO:0042221 320 0.011
Rat
positive regulation of ras protein signal transduction GO:0046579 1 0.011
alcohol biosynthetic process GO:0046165 2 0.011
lamellipodium assembly GO:0030032 1 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
nitric oxide metabolic process GO:0046209 2 0.011
organonitrogen compound biosynthetic process GO:1901566 47 0.011
Rat
regulation of neuron projection development GO:0010975 40 0.011
calcium ion dependent exocytosis GO:0017156 1 0.011
protein phosphorylation GO:0006468 47 0.011
negative regulation of cellular metabolic process GO:0031324 77 0.011
negative regulation of transcription dna templated GO:0045892 45 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.011
meiosis i GO:0007127 1 0.011
negative regulation of cell death GO:0060548 60 0.011
adherens junction maintenance GO:0034334 2 0.011
hypothalamus cell differentiation GO:0021979 4 0.011
protein modification process GO:0036211 100 0.011
carbohydrate homeostasis GO:0033500 1 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
positive regulation of apoptotic signaling pathway GO:2001235 1 0.011
regulation of dendrite development GO:0050773 3 0.011
glucose homeostasis GO:0042593 1 0.011
regulation of lipid transport GO:0032368 4 0.011
regulation of protein localization to nucleus GO:1900180 2 0.011
regulation of apoptotic process GO:0042981 98 0.011
lymphocyte proliferation GO:0046651 1 0.011
regulation of protein complex assembly GO:0043254 3 0.011
glucose import GO:0046323 2 0.011
cellular homeostasis GO:0019725 26 0.011
semicircular canal development GO:0060872 24 0.011
formation of primary germ layer GO:0001704 62 0.011
lateral line system development GO:0048925 76 0.011
mechanosensory lateral line system development GO:0048881 49 0.011
fatty acid transport GO:0015908 1 0.011
intracellular signal transduction GO:0035556 85 0.010
positive regulation of developmental process GO:0051094 50 0.010
regulation of dna replication GO:0006275 3 0.010
carbon dioxide transport GO:0015670 3 0.010
regulation of programmed cell death GO:0043067 101 0.010
intracellular ph reduction GO:0051452 1 0.010
negative regulation of catabolic process GO:0009895 3 0.010
rna transport GO:0050658 2 0.010
cellular ketone metabolic process GO:0042180 11 0.010
regulation of heart contraction GO:0008016 32 0.010
regulation of intracellular protein transport GO:0033157 3 0.010
regulation of neuron differentiation GO:0045664 56 0.010
purine nucleotide biosynthetic process GO:0006164 20 0.010
Rat
negative regulation of multi organism process GO:0043901 3 0.010
macromolecular complex disassembly GO:0032984 1 0.010

pkm2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.059
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016
disease of anatomical entity DOID:7 0 0.014
central nervous system disease DOID:331 0 0.014
neurodegenerative disease DOID:1289 0 0.014
nervous system disease DOID:863 0 0.014
immune system disease DOID:2914 0 0.011
hematopoietic system disease DOID:74 0 0.011