Danio rerio

0 known processes

plekhf2

pleckstrin homology domain containing, family F (with FYVE domain) member 2

(Aliases: zgc:56073,MGC56073)

plekhf2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to carbohydrate GO:0009743 3 0.134
lipid storage GO:0019915 1 0.128
maintenance of location GO:0051235 4 0.084
aging GO:0007568 2 0.068
ubiquitin dependent protein catabolic process GO:0006511 3 0.067
cellular protein catabolic process GO:0044257 4 0.067
positive regulation of catabolic process GO:0009896 4 0.056
lipid homeostasis GO:0055088 3 0.055
response to hexose GO:0009746 3 0.054
positive regulation of cellular catabolic process GO:0031331 3 0.054
response to glucose GO:0009749 3 0.050
larval development GO:0002164 2 0.049
regulation of establishment of protein localization GO:0070201 4 0.048
cellular macromolecule metabolic process GO:0044260 391 0.046
response to monosaccharide GO:0034284 3 0.039
regulation of mrna processing GO:0050684 3 0.038
organic substance biosynthetic process GO:1901576 289 0.038
peptidyl lysine acetylation GO:0018394 2 0.038
regulation of cellular metabolic process GO:0031323 320 0.037
response to topologically incorrect protein GO:0035966 2 0.037
muscle structure development GO:0061061 196 0.035
amine metabolic process GO:0009308 2 0.034
locomotion GO:0040011 313 0.032
cellular protein metabolic process GO:0044267 129 0.032
regulation of metabolic process GO:0019222 359 0.032
negative regulation of response to stimulus GO:0048585 104 0.031
cellular carbohydrate metabolic process GO:0044262 4 0.031
macromolecule biosynthetic process GO:0009059 227 0.031
regulation of rna biosynthetic process GO:2001141 213 0.031
regulation of circadian rhythm GO:0042752 4 0.030
cellular response to external stimulus GO:0071496 2 0.030
cell motility GO:0048870 244 0.030
transport GO:0006810 220 0.029
cellular response to nutrient levels GO:0031669 2 0.029
protein metabolic process GO:0019538 183 0.028
cellular response to topologically incorrect protein GO:0035967 2 0.028
protein acylation GO:0043543 3 0.028
organic acid metabolic process GO:0006082 31 0.028
regionalization GO:0003002 274 0.028
modification dependent macromolecule catabolic process GO:0043632 3 0.027
guanosine containing compound catabolic process GO:1901069 2 0.027
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.027
regulation of carbohydrate metabolic process GO:0006109 4 0.027
oxoacid metabolic process GO:0043436 31 0.026
modification dependent protein catabolic process GO:0019941 3 0.026
establishment of localization GO:0051234 244 0.026
regulation of glucose import GO:0046324 1 0.026
cellular amine metabolic process GO:0044106 2 0.026
rna biosynthetic process GO:0032774 181 0.026
cellular ketone metabolic process GO:0042180 11 0.025
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.025
embryonic organ morphogenesis GO:0048562 274 0.025
regulation of cellular amine metabolic process GO:0033238 0 0.025
regulation of cytokine production GO:0001817 3 0.025
cellular macromolecule biosynthetic process GO:0034645 224 0.024
response to chemical GO:0042221 320 0.024
stem cell maintenance GO:0019827 4 0.024
mitochondrion organization GO:0007005 4 0.024
sympathetic nervous system development GO:0048485 3 0.024
localization of cell GO:0051674 244 0.023
nuclear transport GO:0051169 4 0.023
regulation of response to nutrient levels GO:0032107 1 0.023
gene expression GO:0010467 252 0.023
nitrogen compound metabolic process GO:0006807 319 0.023
regulation of protein catabolic process GO:0042176 1 0.023
proteasomal protein catabolic process GO:0010498 2 0.023
regulation of meiotic cell cycle GO:0051445 1 0.023
glucose homeostasis GO:0042593 1 0.022
cellular response to starvation GO:0009267 1 0.022
cell migration GO:0016477 237 0.022
positive regulation of map kinase activity GO:0043406 3 0.022
transcription dna templated GO:0006351 181 0.022
cellular response to extracellular stimulus GO:0031668 2 0.022
positive regulation of transport GO:0051050 2 0.022
brain development GO:0007420 293 0.021
positive regulation of cell cycle GO:0045787 3 0.021
establishment of protein localization to plasma membrane GO:0090002 1 0.021
gtp metabolic process GO:0046039 4 0.021
negative regulation of protein phosphorylation GO:0001933 4 0.021
hormone transport GO:0009914 2 0.021
negative regulation of response to cytokine stimulus GO:0060761 2 0.021
hormone secretion GO:0046879 2 0.021
macromolecule modification GO:0043412 111 0.021
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.020
regulation of protein localization to plasma membrane GO:1903076 1 0.020
cellular localization GO:0051641 97 0.020
stem cell division GO:0017145 1 0.019
cellular response to chemical stimulus GO:0070887 157 0.019
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.019
gtp catabolic process GO:0006184 2 0.019
regulation of gtp catabolic process GO:0033124 2 0.019
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.019
cellular component movement GO:0006928 335 0.019
response to amino acid GO:0043200 2 0.019
organelle localization GO:0051640 49 0.019
regulation of response to extracellular stimulus GO:0032104 1 0.019
regulation of glucose transport GO:0010827 1 0.019
response to wounding GO:0009611 116 0.018
phosphate containing compound metabolic process GO:0006796 108 0.018
cellular nitrogen compound biosynthetic process GO:0044271 218 0.018
regulation of dendrite development GO:0050773 3 0.018
negative regulation of protein kinase activity GO:0006469 4 0.018
cellular nitrogen compound metabolic process GO:0034641 290 0.017
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 1 0.017
protein homooligomerization GO:0051260 3 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
positive regulation of gtpase activity GO:0043547 1 0.017
carbohydrate homeostasis GO:0033500 1 0.017
nucleocytoplasmic transport GO:0006913 4 0.017
cell aging GO:0007569 2 0.017
carbohydrate biosynthetic process GO:0016051 1 0.016
germ line stem cell maintenance GO:0030718 2 0.016
protein localization to plasma membrane GO:0072659 1 0.016
phagocytosis GO:0006909 3 0.016
activation of mapk activity GO:0000187 3 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.016
rna metabolic process GO:0016070 219 0.016
kidney development GO:0001822 92 0.016
response to vitamin GO:0033273 3 0.016
positive regulation of glucose transport GO:0010828 1 0.015
cell morphogenesis involved in differentiation GO:0000904 195 0.015
exocytosis GO:0006887 1 0.015
cell cell recognition GO:0009988 1 0.015
cellular protein modification process GO:0006464 100 0.015
multicellular organism growth GO:0035264 4 0.015
fertilization GO:0009566 3 0.015
single organism metabolic process GO:0044710 217 0.015
heterocycle biosynthetic process GO:0018130 215 0.015
er to golgi vesicle mediated transport GO:0006888 1 0.015
regulation of primary metabolic process GO:0080090 311 0.015
olfactory lobe development GO:0021988 4 0.014
tube morphogenesis GO:0035239 349 0.014
regulation of gtpase activity GO:0043087 2 0.014
regulation of stem cell differentiation GO:2000736 4 0.014
reactive nitrogen species metabolic process GO:2001057 0 0.014
adult behavior GO:0030534 2 0.014
response to xenobiotic stimulus GO:0009410 45 0.014
leukocyte proliferation GO:0070661 1 0.014
protein acetylation GO:0006473 2 0.013
regulation of reproductive process GO:2000241 4 0.013
vasculature development GO:0001944 278 0.013
regulation of nucleotide catabolic process GO:0030811 2 0.013
cellular biosynthetic process GO:0044249 286 0.013
eye development GO:0001654 277 0.013
positive regulation of lipid metabolic process GO:0045834 1 0.013
stem cell proliferation GO:0072089 4 0.013
ameboidal type cell migration GO:0001667 143 0.013
positive regulation of gtp catabolic process GO:0033126 1 0.013
protein targeting to nucleus GO:0044744 3 0.013
macroautophagy GO:0016236 1 0.013
protein import GO:0017038 3 0.013
internal protein amino acid acetylation GO:0006475 2 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.012
positive regulation of carbohydrate metabolic process GO:0045913 1 0.012
phosphorylation GO:0016310 69 0.012
regulation of dna replication GO:0006275 3 0.012
peptide transport GO:0015833 1 0.012
protein localization to nucleus GO:0034504 3 0.012
regulation of cell development GO:0060284 100 0.012
biosynthetic process GO:0009058 294 0.012
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.012
chordate embryonic development GO:0043009 271 0.012
protein secretion GO:0009306 1 0.012
lateral inhibition GO:0046331 1 0.012
regulation of signal transduction GO:0009966 225 0.012
sensory organ development GO:0007423 393 0.012
heart development GO:0007507 313 0.012
neuroblast proliferation GO:0007405 2 0.011
cellular response to light stimulus GO:0071482 4 0.011
regulation of synapse organization GO:0050807 3 0.011
homeostatic process GO:0042592 142 0.011
regulation of inflammatory response GO:0050727 2 0.011
autophagy GO:0006914 4 0.011
regulation of cell shape GO:0008360 1 0.011
negative regulation of cytokine production GO:0001818 1 0.011
regulation of signaling GO:0023051 235 0.011
regulation of biological quality GO:0065008 263 0.011
regulation of metal ion transport GO:0010959 4 0.011
negative regulation of kinase activity GO:0033673 4 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
cognition GO:0050890 1 0.011
negative regulation of biological process GO:0048519 304 0.011
positive regulation of cell division GO:0051781 2 0.011
regulation of biosynthetic process GO:0009889 250 0.011
glycerolipid biosynthetic process GO:0045017 1 0.010
single fertilization GO:0007338 3 0.010
establishment of protein localization to organelle GO:0072594 4 0.010
regulation of autophagy GO:0010506 3 0.010
cytokinesis GO:0000910 3 0.010
energy reserve metabolic process GO:0006112 2 0.010
negative regulation of signaling GO:0023057 96 0.010
negative regulation of gene expression GO:0010629 65 0.010
regulation of macromolecule biosynthetic process GO:0010556 225 0.010
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.010
regulation of tube size GO:0035150 2 0.010
nucleobase containing compound biosynthetic process GO:0034654 205 0.010
water homeostasis GO:0030104 4 0.010
meiotic cell cycle process GO:1903046 3 0.010
internal peptidyl lysine acetylation GO:0018393 2 0.010
organic cyclic compound metabolic process GO:1901360 301 0.010
localization within membrane GO:0051668 1 0.010
purine nucleoside monophosphate catabolic process GO:0009128 4 0.010
negative regulation of cytoplasmic transport GO:1903650 2 0.010
nitric oxide biosynthetic process GO:0006809 2 0.010
development of primary female sexual characteristics GO:0046545 4 0.010

plekhf2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.016
lipid storage disease DOID:9455 0 0.016
lysosomal storage disease DOID:3211 0 0.016
inherited metabolic disorder DOID:655 0 0.016
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.011