Danio rerio

50 known processes

plrg1

pleiotropic regulator 1

(Aliases: zgc:55651,wu:fi74f01,MGC55651,MGC86603,MGC174842,zgc:86603)

plrg1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.240
Worm
nitrogen compound metabolic process GO:0006807 319 0.228
Yeast
cellular nitrogen compound metabolic process GO:0034641 290 0.182
Yeast
cellular aromatic compound metabolic process GO:0006725 295 0.177
Yeast
regulation of meiotic cell cycle GO:0051445 1 0.170
gene expression GO:0010467 252 0.156
Yeast
embryo development ending in birth or egg hatching GO:0009792 271 0.153
Worm
rna metabolic process GO:0016070 219 0.147
Yeast
nuclear transport GO:0051169 4 0.142
meiotic nuclear division GO:0007126 4 0.115
aging GO:0007568 2 0.109
regulation of biological quality GO:0065008 263 0.102
mrna metabolic process GO:0016071 20 0.097
Yeast
nucleocytoplasmic transport GO:0006913 4 0.087
organic cyclic compound metabolic process GO:1901360 301 0.083
Yeast
rna localization GO:0006403 4 0.081
locomotion GO:0040011 313 0.075
Worm
heterocycle metabolic process GO:0046483 290 0.075
Yeast
meiotic cell cycle process GO:1903046 3 0.071
gtp metabolic process GO:0046039 4 0.060
phosphate containing compound metabolic process GO:0006796 108 0.059
nucleobase containing compound metabolic process GO:0006139 274 0.057
Yeast
mrna transport GO:0051028 2 0.056
immune system development GO:0002520 191 0.055
regulation of metabolic process GO:0019222 359 0.055
cellular carbohydrate metabolic process GO:0044262 4 0.054
single organism localization GO:1902578 225 0.054
Fly
establishment of localization GO:0051234 244 0.053
Fly
nuclear pore organization GO:0006999 2 0.051
gtp catabolic process GO:0006184 2 0.044
heart development GO:0007507 313 0.044
nuclear export GO:0051168 1 0.042
protein dephosphorylation GO:0006470 3 0.042
meiotic chromosome segregation GO:0045132 3 0.041
response to stress GO:0006950 263 0.040
cellular macromolecule metabolic process GO:0044260 391 0.039
Yeast
nucleic acid transport GO:0050657 2 0.039
organonitrogen compound metabolic process GO:1901564 74 0.038
apoptotic process GO:0006915 116 0.037
negative regulation of biological process GO:0048519 304 0.035
regulation of mrna processing GO:0050684 3 0.035
mitotic cell cycle GO:0000278 64 0.035
Mouse
response to abiotic stimulus GO:0009628 122 0.035
small molecule metabolic process GO:0044281 77 0.034
establishment of rna localization GO:0051236 3 0.034
nucleic acid metabolic process GO:0090304 244 0.034
Yeast
regulation of reproductive process GO:2000241 4 0.033
hemopoiesis GO:0030097 183 0.033
regulation of cell shape GO:0008360 1 0.033
hematopoietic or lymphoid organ development GO:0048534 191 0.032
regulation of primary metabolic process GO:0080090 311 0.032
cellular macromolecule biosynthetic process GO:0034645 224 0.032
regulation of mitochondrion organization GO:0010821 1 0.032
nucleobase containing small molecule metabolic process GO:0055086 32 0.031
cell death GO:0008219 121 0.031
cellular biosynthetic process GO:0044249 286 0.031
regulation of nitrogen compound metabolic process GO:0051171 251 0.029
positive regulation of biological process GO:0048518 253 0.029
Mouse
embryonic organ development GO:0048568 381 0.028
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.028
death GO:0016265 121 0.028
nucleobase containing compound biosynthetic process GO:0034654 205 0.028
phosphorus metabolic process GO:0006793 109 0.027
organelle organization GO:0006996 227 0.027
Fly
regulation of anatomical structure morphogenesis GO:0022603 130 0.027
stem cell maintenance GO:0019827 4 0.025
regulation of multicellular organismal development GO:2000026 223 0.025
adult behavior GO:0030534 2 0.025
programmed cell death GO:0012501 119 0.025
oocyte anterior posterior axis specification GO:0007314 4 0.025
regeneration GO:0031099 91 0.025
rna export from nucleus GO:0006405 1 0.025
regulation of response to stimulus GO:0048583 269 0.025
regulation of signal transduction GO:0009966 225 0.025
regulation of autophagy GO:0010506 3 0.025
regulation of protein transport GO:0051223 3 0.025
synaptic vesicle transport GO:0048489 1 0.024
multi organism process GO:0051704 134 0.024
single organism metabolic process GO:0044710 217 0.024
localization of cell GO:0051674 244 0.024
regulation of macromolecule metabolic process GO:0060255 317 0.024
single organism transport GO:0044765 206 0.024
Fly
fertilization GO:0009566 3 0.024
negative regulation of metabolic process GO:0009892 86 0.023
rna transport GO:0050658 2 0.023
positive regulation of apoptotic process GO:0043065 29 0.023
nuclear division GO:0000280 23 0.023
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.022
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.022
glucose homeostasis GO:0042593 1 0.022
response to organic substance GO:0010033 153 0.022
microtubule based process GO:0007017 60 0.022
rna modification GO:0009451 2 0.020
organic substance biosynthetic process GO:1901576 289 0.020
positive regulation of catabolic process GO:0009896 4 0.020
regulation of biosynthetic process GO:0009889 250 0.020
regulation of molecular function GO:0065009 70 0.020
negative regulation of developmental process GO:0051093 65 0.020
response to chemical GO:0042221 320 0.020
positive regulation of transport GO:0051050 2 0.020
positive regulation of cellular metabolic process GO:0031325 94 0.020
purine containing compound metabolic process GO:0072521 29 0.019
purine nucleoside monophosphate catabolic process GO:0009128 4 0.019
aromatic compound biosynthetic process GO:0019438 217 0.019
cellular ketone metabolic process GO:0042180 11 0.019
pole plasm assembly GO:0007315 4 0.019
atp catabolic process GO:0006200 4 0.018
maintenance of location GO:0051235 4 0.018
multicellular organism growth GO:0035264 4 0.018
cellular nitrogen compound biosynthetic process GO:0044271 218 0.018
regulation of synaptic plasticity GO:0048167 1 0.018
alternative mrna splicing via spliceosome GO:0000380 1 0.018
cellular response to chemical stimulus GO:0070887 157 0.017
ribonucleotide metabolic process GO:0009259 27 0.017
negative regulation of epithelial cell proliferation GO:0050680 1 0.017
lipid storage GO:0019915 1 0.017
positive regulation of apoptotic signaling pathway GO:2001235 1 0.017
negative regulation of cellular process GO:0048523 283 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
regulation of cellular biosynthetic process GO:0031326 245 0.017
response to temperature stimulus GO:0009266 15 0.017
organic cyclic compound biosynthetic process GO:1901362 223 0.017
nuclear import GO:0051170 3 0.017
purine ribonucleotide metabolic process GO:0009150 27 0.017
cellular localization GO:0051641 97 0.017
Mouse Fly
carbohydrate derivative metabolic process GO:1901135 61 0.017
germ cell development GO:0007281 22 0.016
regulation of cellular metabolic process GO:0031323 320 0.016
guanosine containing compound catabolic process GO:1901069 2 0.016
regulation of synapse organization GO:0050807 3 0.016
regulation of rna metabolic process GO:0051252 224 0.016
organism emergence from protective structure GO:0071684 4 0.016
mitochondrion organization GO:0007005 4 0.016
positive regulation of cellular catabolic process GO:0031331 3 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.016
spliceosomal snrnp assembly GO:0000387 2 0.016
heterocycle biosynthetic process GO:0018130 215 0.016
regulation of nucleic acid templated transcription GO:1903506 213 0.016
regulation of establishment of protein localization GO:0070201 4 0.016
regulation of response to stress GO:0080134 36 0.016
cell motility GO:0048870 244 0.016
single organism reproductive process GO:0044702 40 0.016
response to monosaccharide GO:0034284 3 0.016
negative regulation of muscle tissue development GO:1901862 2 0.015
carbohydrate biosynthetic process GO:0016051 1 0.015
protein metabolic process GO:0019538 183 0.015
nucleotide metabolic process GO:0009117 28 0.015
purine nucleotide metabolic process GO:0006163 27 0.015
response to glucose GO:0009749 3 0.015
organophosphate metabolic process GO:0019637 37 0.015
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.015
response to external stimulus GO:0009605 264 0.015
cellular amine metabolic process GO:0044106 2 0.015
protein phosphorylation GO:0006468 47 0.015
transport GO:0006810 220 0.015
Fly
cell cycle process GO:0022402 53 0.015
Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.015
cellular component disassembly GO:0022411 1 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
chromosome localization GO:0050000 2 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
neurotransmitter transport GO:0006836 2 0.015
phosphorylation GO:0016310 69 0.014
cellular protein metabolic process GO:0044267 129 0.014
gland development GO:0048732 143 0.014
response to carbohydrate GO:0009743 3 0.014
regulation of gtp catabolic process GO:0033124 2 0.014
biosynthetic process GO:0009058 294 0.014
regulation of apoptotic process GO:0042981 98 0.014
regulation of exocytosis GO:0017157 1 0.014
synaptic vesicle localization GO:0097479 1 0.014
regulation of developmental process GO:0050793 247 0.014
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.014
nucleoside phosphate biosynthetic process GO:1901293 21 0.014
response to drug GO:0042493 3 0.014
regulation of dna replication GO:0006275 3 0.013
cell migration GO:0016477 237 0.013
rna 3 end processing GO:0031123 2 0.013
rna biosynthetic process GO:0032774 181 0.013
stem cell development GO:0048864 82 0.013
purine ribonucleoside biosynthetic process GO:0046129 2 0.013
establishment of synaptic vesicle localization GO:0097480 1 0.013
regulation of cell proliferation GO:0042127 37 0.013
purine ribonucleotide biosynthetic process GO:0009152 20 0.013
organic acid metabolic process GO:0006082 31 0.013
nucleobase containing compound transport GO:0015931 2 0.013
chordate embryonic development GO:0043009 271 0.013
mitotic cell cycle process GO:1903047 48 0.013
Mouse
segmentation GO:0035282 97 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
transcription dna templated GO:0006351 181 0.013
response to biotic stimulus GO:0009607 97 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
mrna export from nucleus GO:0006406 1 0.012
regulation of carbohydrate metabolic process GO:0006109 4 0.012
protein import into nucleus GO:0006606 3 0.012
negative regulation of endopeptidase activity GO:0010951 10 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
nucleic acid templated transcription GO:0097659 181 0.012
liver development GO:0001889 96 0.012
cytoskeleton organization GO:0007010 96 0.012
negative regulation of signaling GO:0023057 96 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
cellular response to organic substance GO:0071310 105 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
nucleoside phosphate metabolic process GO:0006753 28 0.011
somatic stem cell maintenance GO:0035019 1 0.011
regulation of phosphate metabolic process GO:0019220 43 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.011
stem cell differentiation GO:0048863 117 0.011
protein targeting to nucleus GO:0044744 3 0.011
negative regulation of synapse assembly GO:0051964 2 0.011
regulation of hydrolase activity GO:0051336 28 0.011
negative regulation of kinase activity GO:0033673 4 0.011
purine containing compound biosynthetic process GO:0072522 20 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
gamete generation GO:0007276 33 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
synaptic vesicle recycling GO:0036465 1 0.011
generation of neurons GO:0048699 385 0.011
positive regulation of cell cycle GO:0045787 3 0.011
Mouse
regulation of protein targeting GO:1903533 2 0.011
phagocytosis GO:0006909 3 0.011
purine nucleoside biosynthetic process GO:0042451 2 0.011
multicellular organism reproduction GO:0032504 35 0.011
cellular response to extracellular stimulus GO:0031668 2 0.011
single organism nuclear import GO:1902593 3 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
dna templated transcription elongation GO:0006354 3 0.011
carbohydrate homeostasis GO:0033500 1 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
meiosis i GO:0007127 1 0.010
regulation of synapse assembly GO:0051963 3 0.010
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.010
angiogenesis GO:0001525 158 0.010
regulation of gene expression GO:0010468 265 0.010
brain development GO:0007420 293 0.010
meiotic cell cycle GO:0051321 5 0.010
digestive system development GO:0055123 289 0.010
positive regulation of metabolic process GO:0009893 108 0.010
regulation of organ growth GO:0046620 3 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.010
response to external biotic stimulus GO:0043207 97 0.010
metallo sulfur cluster assembly GO:0031163 1 0.010
non recombinational repair GO:0000726 2 0.010

plrg1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.020
sensory system disease DOID:0050155 0 0.014
auditory system disease DOID:2742 0 0.014
nonsyndromic deafness DOID:0050563 0 0.014