Danio rerio

0 known processes

plxnb2b

plexin b2b

plxnb2b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
chordate embryonic development GO:0043009 271 0.469
Zebrafish Mouse
embryonic organ development GO:0048568 381 0.283
Zebrafish
collateral sprouting in absence of injury GO:0048669 4 0.193
Zebrafish
sister chromatid cohesion GO:0007062 2 0.151
lateral line system development GO:0048925 76 0.131
skeletal system morphogenesis GO:0048705 102 0.131
Zebrafish
regulation of collateral sprouting in absence of injury GO:0048696 4 0.127
Zebrafish
sensory organ development GO:0007423 393 0.106
cell motility GO:0048870 244 0.102
Mouse
meiotic nuclear division GO:0007126 4 0.095
response to chemical GO:0042221 320 0.073
Zebrafish
neurological system process GO:0050877 62 0.071
morphogenesis of an epithelium GO:0002009 333 0.070
Mouse
neuron development GO:0048666 262 0.064
Zebrafish Mouse
mesenchymal cell development GO:0014031 78 0.062
head development GO:0060322 303 0.062
Mouse
mesenchymal cell differentiation GO:0048762 87 0.061
regulation of reactive oxygen species metabolic process GO:2000377 2 0.060
skeletal system development GO:0001501 181 0.059
Zebrafish
sensory system development GO:0048880 76 0.059
larval development GO:0002164 2 0.057
embryonic organ morphogenesis GO:0048562 274 0.054
Zebrafish
branching morphogenesis of a nerve GO:0048755 4 0.053
Zebrafish
localization of cell GO:0051674 244 0.051
Mouse
enteric nervous system development GO:0048484 12 0.050
epithelial tube morphogenesis GO:0060562 148 0.048
Mouse
regulation of multicellular organism growth GO:0040014 4 0.047
modification dependent macromolecule catabolic process GO:0043632 3 0.045
embryonic skeletal system development GO:0048706 97 0.044
Zebrafish
lens development in camera type eye GO:0002088 22 0.044
cellular component morphogenesis GO:0032989 336 0.043
Zebrafish Mouse
chromosome organization involved in meiosis GO:0070192 1 0.043
anterior posterior pattern specification GO:0009952 152 0.043
embryonic skeletal joint morphogenesis GO:0060272 3 0.043
Zebrafish
response to monosaccharide GO:0034284 3 0.042
posterior lateral line system development GO:0048915 46 0.042
mesenchyme development GO:0060485 127 0.041
locus ceruleus development GO:0021703 3 0.041
ubiquitin dependent protein catabolic process GO:0006511 3 0.041
tube closure GO:0060606 1 0.040
Mouse
regulation of gene silencing GO:0060968 1 0.039
axon development GO:0061564 166 0.039
Zebrafish Mouse
regulation of protein ubiquitination GO:0031396 3 0.038
muscle cell migration GO:0014812 4 0.037
positive regulation of catabolic process GO:0009896 4 0.036
embryonic skeletal joint development GO:0072498 3 0.036
Zebrafish
glutamate receptor signaling pathway GO:0007215 1 0.036
regulation of nucleotide catabolic process GO:0030811 2 0.035
Mouse
cell matrix adhesion GO:0007160 4 0.035
sensory perception of chemical stimulus GO:0007606 3 0.035
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.035
cellular component movement GO:0006928 335 0.035
Zebrafish Mouse
cognition GO:0050890 1 0.034
regulation of developmental process GO:0050793 247 0.034
Zebrafish Mouse
cell migration GO:0016477 237 0.034
Mouse
embryo development ending in birth or egg hatching GO:0009792 271 0.033
Zebrafish Mouse
neural crest cell differentiation GO:0014033 72 0.031
response to stress GO:0006950 263 0.031
cerebellar granular layer development GO:0021681 3 0.031
regulation of cell communication GO:0010646 232 0.030
Mouse
neuron migration GO:0001764 22 0.030
Mouse
modification dependent protein catabolic process GO:0019941 3 0.029
mitotic sister chromatid cohesion GO:0007064 2 0.029
cellular component assembly GO:0022607 170 0.029
ear development GO:0043583 127 0.029
lateral line development GO:0048882 66 0.028
aromatic compound biosynthetic process GO:0019438 217 0.028
negative regulation of cellular process GO:0048523 283 0.028
stem cell maintenance GO:0019827 4 0.028
immune system development GO:0002520 191 0.028
regulation of cell maturation GO:1903429 1 0.027
stem cell development GO:0048864 82 0.027
detection of stimulus involved in sensory perception GO:0050906 21 0.027
response to drug GO:0042493 3 0.026
regulation of cellular biosynthetic process GO:0031326 245 0.026
sphingolipid biosynthetic process GO:0030148 2 0.026
regulation of nucleoside metabolic process GO:0009118 2 0.026
Mouse
positive regulation of macromolecule metabolic process GO:0010604 93 0.025
gene expression GO:0010467 252 0.025
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.025
cellular protein catabolic process GO:0044257 4 0.025
nitric oxide biosynthetic process GO:0006809 2 0.025
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.024
stem cell differentiation GO:0048863 117 0.024
nucleobase containing compound biosynthetic process GO:0034654 205 0.024
blood vessel morphogenesis GO:0048514 216 0.024
Zebrafish
neural crest formation GO:0014029 14 0.023
rna localization GO:0006403 4 0.022
mechanosensory lateral line system development GO:0048881 49 0.022
intracellular mrna localization GO:0008298 1 0.022
protein import GO:0017038 3 0.022
positive regulation of cellular component biogenesis GO:0044089 3 0.022
response to light stimulus GO:0009416 46 0.021
angiogenesis GO:0001525 158 0.021
Zebrafish
regulation of cytokine production GO:0001817 3 0.020
regulation of cell shape GO:0008360 1 0.020
Mouse
signal transduction GO:0007165 455 0.020
Mouse
transmission of nerve impulse GO:0019226 19 0.020
axon midline choice point recognition GO:0016199 4 0.020
negative regulation of nuclear division GO:0051784 3 0.020
common bile duct development GO:0061009 13 0.020
protein stabilization GO:0050821 2 0.020
regulation of protein catabolic process GO:0042176 1 0.019
mitotic sister chromatid segregation GO:0000070 6 0.019
lipid catabolic process GO:0016042 4 0.019
primary neural tube formation GO:0014020 1 0.019
Mouse
regulation of nitrogen compound metabolic process GO:0051171 251 0.019
Mouse
regulation of cell differentiation GO:0045595 142 0.019
Zebrafish Mouse
regulation of reproductive process GO:2000241 4 0.019
neuron differentiation GO:0030182 353 0.018
Zebrafish Mouse
negative regulation of dna replication GO:0008156 2 0.018
negative regulation of biological process GO:0048519 304 0.018
regulation of cytoplasmic transport GO:1903649 4 0.018
autonomic nervous system development GO:0048483 19 0.018
pharyngeal system development GO:0060037 18 0.018
negative regulation of dna metabolic process GO:0051053 4 0.018
taxis GO:0042330 109 0.018
Zebrafish
somitogenesis GO:0001756 87 0.018
guanosine containing compound metabolic process GO:1901068 4 0.018
Mouse
leukocyte proliferation GO:0070661 1 0.017
autophagy GO:0006914 4 0.017
hematopoietic or lymphoid organ development GO:0048534 191 0.017
phagocytosis GO:0006909 3 0.017
positive regulation of epithelial cell proliferation GO:0050679 1 0.017
regulation of cellular protein catabolic process GO:1903362 1 0.017
epithelial cell differentiation GO:0030855 116 0.017
positive regulation of striated muscle cell differentiation GO:0051155 1 0.017
multicellular organism growth GO:0035264 4 0.017
central nervous system myelination GO:0022010 2 0.017
liver development GO:0001889 96 0.017
regulation of gtp catabolic process GO:0033124 2 0.017
Mouse
response to carbohydrate GO:0009743 3 0.016
nephron tubule morphogenesis GO:0072078 1 0.016
protein complex subunit organization GO:0071822 46 0.016
response to external stimulus GO:0009605 264 0.016
Zebrafish
central nervous system development GO:0007417 387 0.016
Mouse
regulation of protein complex assembly GO:0043254 3 0.016
nuclear transport GO:0051169 4 0.016
regulation of response to stimulus GO:0048583 269 0.016
Mouse
membrane lipid biosynthetic process GO:0046467 2 0.016
phagocytosis engulfment GO:0006911 1 0.016
establishment of protein localization to organelle GO:0072594 4 0.016
regulation of response to cytokine stimulus GO:0060759 3 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.016
cellular response to retinoic acid GO:0071300 1 0.016
proteasomal protein catabolic process GO:0010498 2 0.016
nuclear envelope organization GO:0006998 2 0.016
positive regulation of developmental process GO:0051094 50 0.015
Mouse
inner ear development GO:0048839 126 0.015
regulation of primary metabolic process GO:0080090 311 0.015
Mouse
notochord development GO:0030903 54 0.015
nephron epithelium morphogenesis GO:0072088 1 0.015
peptidyl serine phosphorylation GO:0018105 1 0.015
axon guidance GO:0007411 86 0.015
Zebrafish
response to superoxide GO:0000303 2 0.015
neural crest cell development GO:0014032 62 0.015
embryonic skeletal system morphogenesis GO:0048704 93 0.015
Zebrafish
cellular protein metabolic process GO:0044267 129 0.015
Mouse
regulation of cellular component organization GO:0051128 86 0.015
Zebrafish Mouse
hepaticobiliary system development GO:0061008 98 0.015
vasculature development GO:0001944 278 0.015
Zebrafish
aging GO:0007568 2 0.015
regulation of epithelial cell proliferation GO:0050678 3 0.015
positive regulation of cellular biosynthetic process GO:0031328 68 0.015
ameboidal type cell migration GO:0001667 143 0.015
regulation of meiotic cell cycle GO:0051445 1 0.014
hemopoiesis GO:0030097 183 0.014
regulation of organelle assembly GO:1902115 4 0.014
embryonic epithelial tube formation GO:0001838 17 0.014
Mouse
locomotion GO:0040011 313 0.014
Zebrafish Mouse
directional locomotion GO:0033058 1 0.014
meiotic chromosome segregation GO:0045132 3 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.014
regulation of metabolic process GO:0019222 359 0.014
Mouse
nephron morphogenesis GO:0072028 2 0.014
cellular response to starvation GO:0009267 1 0.014
cell morphogenesis involved in differentiation GO:0000904 195 0.014
Zebrafish Mouse
mitochondrion organization GO:0007005 4 0.014
immunoglobulin mediated immune response GO:0016064 3 0.014
myeloid cell differentiation GO:0030099 86 0.014
positive regulation of cellular catabolic process GO:0031331 3 0.014
response to inorganic substance GO:0010035 38 0.014
somite development GO:0061053 96 0.014
regulation of rna metabolic process GO:0051252 224 0.014
positive regulation of apoptotic signaling pathway GO:2001235 1 0.013
cellular response to nutrient levels GO:0031669 2 0.013
nucleic acid metabolic process GO:0090304 244 0.013
regulation of signal transduction GO:0009966 225 0.013
Mouse
regulation of biomineral tissue development GO:0070167 2 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
regulation of receptor activity GO:0010469 2 0.013
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.013
microtubule organizing center organization GO:0031023 1 0.013
regulation of rho protein signal transduction GO:0035023 2 0.013
Mouse
regulation of axon guidance GO:1902667 8 0.013
cell proliferation in hindbrain GO:0021534 4 0.013
axonal defasciculation GO:0007414 2 0.013
Zebrafish
immune system process GO:0002376 241 0.013
gastrulation GO:0007369 208 0.013
tissue remodeling GO:0048771 4 0.013
b cell mediated immunity GO:0019724 3 0.013
response to hexose GO:0009746 3 0.013
regulation of blood vessel size GO:0050880 2 0.013
multicellular organismal signaling GO:0035637 22 0.013
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.013
cytosolic calcium ion transport GO:0060401 3 0.012
cellular nitrogen compound biosynthetic process GO:0044271 218 0.012
segmentation GO:0035282 97 0.012
establishment of localization GO:0051234 244 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.012
convergent extension involved in axis elongation GO:0060028 26 0.012
rhombomere 5 development GO:0021571 4 0.012
regulation of posttranscriptional gene silencing GO:0060147 1 0.012
stem cell proliferation GO:0072089 4 0.012
Mouse
meiosis i GO:0007127 1 0.012
centrosome localization GO:0051642 1 0.012
epithalamus development GO:0021538 10 0.012
positive regulation of secretion GO:0051047 1 0.012
regulation of gtpase activity GO:0043087 2 0.012
Mouse
otic vesicle development GO:0071599 42 0.012
hindbrain development GO:0030902 91 0.012
blood vessel development GO:0001568 246 0.012
Zebrafish
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.012
carbohydrate homeostasis GO:0033500 1 0.012
cellular aromatic compound metabolic process GO:0006725 295 0.012
Mouse
nucleocytoplasmic transport GO:0006913 4 0.012
cell morphogenesis GO:0000902 289 0.012
Zebrafish Mouse
lymphocyte proliferation GO:0046651 1 0.012
regulation of neural precursor cell proliferation GO:2000177 3 0.012
toxin transport GO:1901998 2 0.012
viral process GO:0016032 1 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
positive regulation of cellular metabolic process GO:0031325 94 0.011
response to corticosteroid GO:0031960 1 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.011
tube formation GO:0035148 25 0.011
Mouse
regulation of cell development GO:0060284 100 0.011
Zebrafish Mouse
positive regulation of striated muscle tissue development GO:0045844 1 0.011
regulation of signaling GO:0023051 235 0.011
Mouse
regionalization GO:0003002 274 0.011
immunoglobulin production GO:0002377 1 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.011
regulation of dna replication GO:0006275 3 0.011
negative regulation of protein complex assembly GO:0031333 1 0.011
negative regulation of protein transport GO:0051224 3 0.011
nuclear migration GO:0007097 3 0.011
axonogenesis GO:0007409 152 0.011
Zebrafish Mouse
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 1 0.011
proepicardium development GO:0003342 4 0.011
reactive oxygen species metabolic process GO:0072593 6 0.011
regulation of binding GO:0051098 3 0.011
reactive oxygen species biosynthetic process GO:1903409 1 0.011
glycolipid biosynthetic process GO:0009247 1 0.011
inner ear receptor cell differentiation GO:0060113 29 0.011
sensory perception GO:0007600 39 0.011
optic placode formation involved in camera type eye formation GO:0046619 3 0.011
protein homooligomerization GO:0051260 3 0.011
detection of stimulus GO:0051606 29 0.011
microtubule cytoskeleton organization GO:0000226 33 0.011
protein import into nucleus GO:0006606 3 0.011
regulation of ras gtpase activity GO:0032318 2 0.011
Mouse
positive regulation of gtpase activity GO:0043547 1 0.010
negative regulation of epithelial cell proliferation GO:0050680 1 0.010
rhombomere 6 development GO:0021572 4 0.010
extrinsic apoptotic signaling pathway GO:0097191 3 0.010
i kappab kinase nf kappab signaling GO:0007249 4 0.010
intrahepatic bile duct development GO:0035622 11 0.010
regulation of mitotic cell cycle GO:0007346 25 0.010
response to metal ion GO:0010038 34 0.010
gtp metabolic process GO:0046039 4 0.010
Mouse
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.010
determination of liver left right asymmetry GO:0071910 11 0.010
guanosine containing compound catabolic process GO:1901069 2 0.010
Mouse
regulation of cellular amine metabolic process GO:0033238 0 0.010
response to organic substance GO:0010033 153 0.010
positive regulation of muscle organ development GO:0048636 1 0.010
regulation of production of molecular mediator of immune response GO:0002700 1 0.010
regulation of rho gtpase activity GO:0032319 1 0.010
Mouse

plxnb2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.064
musculoskeletal system disease DOID:17 0 0.021
cardiovascular system disease DOID:1287 0 0.020
nervous system disease DOID:863 0 0.015