Danio rerio

0 known processes

pmch

pro-melanin concentrating hormone

(Aliases: si:ch211-260p3.3)

pmch biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
g protein coupled receptor signaling pathway GO:0007186 74 0.293
response to external stimulus GO:0009605 264 0.223
negative regulation of biological process GO:0048519 304 0.206
regulation of adenylate cyclase activity GO:0045761 6 0.197
regulation of cyclic nucleotide biosynthetic process GO:0030802 15 0.168
primary amino compound metabolic process GO:1901160 1 0.145
regulation of camp biosynthetic process GO:0030817 9 0.129
cellular aromatic compound metabolic process GO:0006725 295 0.105
regulation of ion transmembrane transporter activity GO:0032412 2 0.094
system process GO:0003008 185 0.092
cellular response to chemical stimulus GO:0070887 157 0.089
regulation of cellular metabolic process GO:0031323 320 0.088
adult behavior GO:0030534 2 0.088
heterocycle metabolic process GO:0046483 290 0.081
regulation of primary metabolic process GO:0080090 311 0.081
regulation of nucleotide biosynthetic process GO:0030808 15 0.079
regulation of response to nutrient levels GO:0032107 1 0.077
signal transduction GO:0007165 455 0.076
single organism metabolic process GO:0044710 217 0.071
nucleobase containing compound biosynthetic process GO:0034654 205 0.070
actin polymerization or depolymerization GO:0008154 2 0.066
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.064
cellular nitrogen compound metabolic process GO:0034641 290 0.064
cellular response to estrogen stimulus GO:0071391 24 0.063
regulation of biological quality GO:0065008 263 0.061
cellular response to hormone stimulus GO:0032870 39 0.060
regulation of biosynthetic process GO:0009889 250 0.058
positive regulation of metabolic process GO:0009893 108 0.056
phasic smooth muscle contraction GO:0014821 1 0.056
hormone mediated signaling pathway GO:0009755 9 0.054
nitrogen compound metabolic process GO:0006807 319 0.051
cell surface receptor signaling pathway GO:0007166 325 0.051
development of primary female sexual characteristics GO:0046545 4 0.048
regulation of multicellular organismal process GO:0051239 277 0.047
cellular response to steroid hormone stimulus GO:0071383 31 0.047
regulation of metabolic process GO:0019222 359 0.046
larval development GO:0002164 2 0.046
ovulation cycle process GO:0022602 2 0.045
organic substance biosynthetic process GO:1901576 289 0.044
aromatic compound biosynthetic process GO:0019438 217 0.043
regulation of signaling GO:0023051 235 0.043
regulation of metal ion transport GO:0010959 4 0.042
amine metabolic process GO:0009308 2 0.042
small molecule metabolic process GO:0044281 77 0.042
regulation of response to stimulus GO:0048583 269 0.042
cation transport GO:0006812 81 0.042
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.041
hormone transport GO:0009914 2 0.041
regulation of response to extracellular stimulus GO:0032104 1 0.040
regulation of purine nucleotide biosynthetic process GO:1900371 15 0.039
catechol containing compound metabolic process GO:0009712 2 0.038
metal ion transport GO:0030001 58 0.038
response to stress GO:0006950 263 0.038
regulation of cytokine production GO:0001817 3 0.036
regulation of cellular ketone metabolic process GO:0010565 7 0.036
organic cyclic compound metabolic process GO:1901360 301 0.035
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.034
biosynthetic process GO:0009058 294 0.032
indole containing compound metabolic process GO:0042430 2 0.032
positive regulation of nucleotide biosynthetic process GO:0030810 8 0.032
cellular macromolecule metabolic process GO:0044260 391 0.032
nucleobase containing compound metabolic process GO:0006139 274 0.032
positive regulation of cellular metabolic process GO:0031325 94 0.031
cellular carbohydrate metabolic process GO:0044262 4 0.031
regulation of multicellular organism growth GO:0040014 4 0.031
regulation of calcium ion transport GO:0051924 2 0.031
carbohydrate derivative biosynthetic process GO:1901137 43 0.030
heterocycle biosynthetic process GO:0018130 215 0.030
ion transport GO:0006811 114 0.030
regulation of transporter activity GO:0032409 2 0.030
cellular amine metabolic process GO:0044106 2 0.030
regulation of cyclic nucleotide metabolic process GO:0030799 15 0.030
peptide transport GO:0015833 1 0.029
establishment of localization GO:0051234 244 0.029
release of sequestered calcium ion into cytosol GO:0051209 3 0.029
ion transmembrane transport GO:0034220 91 0.029
cognition GO:0050890 1 0.029
regulation of synapse assembly GO:0051963 3 0.029
cellular response to organic substance GO:0071310 105 0.029
female sex differentiation GO:0046660 4 0.028
response to food GO:0032094 1 0.028
cellular nitrogen compound biosynthetic process GO:0044271 218 0.028
positive regulation of cellular process GO:0048522 201 0.028
organonitrogen compound metabolic process GO:1901564 74 0.028
startle response GO:0001964 4 0.028
inorganic ion transmembrane transport GO:0098660 57 0.028
serotonin metabolic process GO:0042428 1 0.027
positive regulation of cytoskeleton organization GO:0051495 3 0.027
cellular response to oxygen containing compound GO:1901701 20 0.027
regulation of cell shape GO:0008360 1 0.027
positive regulation of cell communication GO:0010647 56 0.027
regulation of sequestering of calcium ion GO:0051282 4 0.027
multicellular organism growth GO:0035264 4 0.027
cyclic nucleotide biosynthetic process GO:0009190 18 0.027
response to xenobiotic stimulus GO:0009410 45 0.027
intracellular signal transduction GO:0035556 85 0.027
regulation of cell communication GO:0010646 232 0.027
dopamine metabolic process GO:0042417 2 0.026
sensory perception GO:0007600 39 0.026
catecholamine metabolic process GO:0006584 2 0.025
response to chemical GO:0042221 320 0.025
positive regulation of lyase activity GO:0051349 6 0.025
regulation of macromolecule metabolic process GO:0060255 317 0.025
cellular response to nutrient levels GO:0031669 2 0.025
camp biosynthetic process GO:0006171 11 0.025
response to organic substance GO:0010033 153 0.025
regulation of protein complex assembly GO:0043254 3 0.025
glycolipid biosynthetic process GO:0009247 1 0.024
positive regulation of cellular component biogenesis GO:0044089 3 0.024
nucleotide biosynthetic process GO:0009165 21 0.024
cellular response to decreased oxygen levels GO:0036294 1 0.024
regulation of reproductive process GO:2000241 4 0.024
generation of neurons GO:0048699 385 0.023
regulation of synapse organization GO:0050807 3 0.023
purine ribonucleotide metabolic process GO:0009150 27 0.023
cellular ketone metabolic process GO:0042180 11 0.023
purine containing compound biosynthetic process GO:0072522 20 0.023
regulation of camp metabolic process GO:0030814 9 0.023
cellular response to hypoxia GO:0071456 1 0.023
circadian sleep wake cycle GO:0042745 2 0.023
circadian sleep wake cycle process GO:0022410 2 0.023
transport GO:0006810 220 0.023
i kappab kinase nf kappab signaling GO:0007249 4 0.022
cellular response to external stimulus GO:0071496 2 0.022
regulation of dna replication GO:0006275 3 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
single organism biosynthetic process GO:0044711 71 0.022
response to dexamethasone GO:0071548 1 0.022
negative regulation of secretion GO:0051048 2 0.022
response to corticosteroid GO:0031960 1 0.022
regulation of cellular biosynthetic process GO:0031326 245 0.022
negative regulation of response to stimulus GO:0048585 104 0.022
sensory perception of pain GO:0019233 1 0.022
multicellular organismal signaling GO:0035637 22 0.021
single organism localization GO:1902578 225 0.021
organonitrogen compound biosynthetic process GO:1901566 47 0.021
regulation of transmembrane transporter activity GO:0022898 2 0.021
protein polymerization GO:0051258 4 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.021
positive regulation of stem cell proliferation GO:2000648 1 0.021
cyclic nucleotide metabolic process GO:0009187 18 0.021
cellular component disassembly GO:0022411 1 0.021
behavior GO:0007610 74 0.021
cell substrate adhesion GO:0031589 4 0.020
hormone secretion GO:0046879 2 0.020
macromolecular complex disassembly GO:0032984 1 0.020
single organism membrane fusion GO:0044801 2 0.020
maintenance of location GO:0051235 4 0.020
multicellular organismal response to stress GO:0033555 2 0.020
neuron differentiation GO:0030182 353 0.020
response to glucocorticoid GO:0051384 1 0.020
guanosine containing compound metabolic process GO:1901068 4 0.020
centrosome organization GO:0051297 1 0.020
ovulation cycle GO:0042698 2 0.020
regulation of epithelial cell proliferation GO:0050678 3 0.019
organelle organization GO:0006996 227 0.019
catechol containing compound biosynthetic process GO:0009713 2 0.019
glucose homeostasis GO:0042593 1 0.019
monoamine transport GO:0015844 1 0.019
neurological system process GO:0050877 62 0.019
negative regulation of hormone secretion GO:0046888 2 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.019
mechanosensory behavior GO:0007638 2 0.019
organic acid metabolic process GO:0006082 31 0.019
cellular response to stress GO:0033554 62 0.019
regulation of nitrogen compound metabolic process GO:0051171 251 0.018
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.018
single organism organelle organization GO:1902589 199 0.018
muscle cell migration GO:0014812 4 0.018
protein targeting to nucleus GO:0044744 3 0.018
regulation of carbohydrate metabolic process GO:0006109 4 0.018
negative regulation of dna replication GO:0008156 2 0.018
protein metabolic process GO:0019538 183 0.018
response to hormone GO:0009725 48 0.018
regulation of macromolecule biosynthetic process GO:0010556 225 0.018
ribonucleotide biosynthetic process GO:0009260 20 0.018
regulation of neurological system process GO:0031644 2 0.018
regulation of programmed cell death GO:0043067 101 0.018
positive regulation of camp biosynthetic process GO:0030819 2 0.018
regulation of gtp catabolic process GO:0033124 2 0.018
cellular response to endogenous stimulus GO:0071495 68 0.018
regulation of bone mineralization GO:0030500 2 0.018
carbohydrate homeostasis GO:0033500 1 0.018
positive regulation of response to stimulus GO:0048584 80 0.018
regulation of lyase activity GO:0051339 12 0.017
positive regulation of transport GO:0051050 2 0.017
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
carboxylic acid metabolic process GO:0019752 22 0.017
carbohydrate derivative metabolic process GO:1901135 61 0.017
xenobiotic metabolic process GO:0006805 4 0.017
nitric oxide biosynthetic process GO:0006809 2 0.017
cellular biosynthetic process GO:0044249 286 0.017
regulation of dendrite development GO:0050773 3 0.017
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.017
response to oxygen containing compound GO:1901700 55 0.017
microtubule organizing center organization GO:0031023 1 0.017
regulation of phosphorus metabolic process GO:0051174 43 0.017
cation transmembrane transport GO:0098655 65 0.017
organophosphate metabolic process GO:0019637 37 0.017
phosphorus metabolic process GO:0006793 109 0.017
regulation of protein depolymerization GO:1901879 1 0.017
neurotransmitter secretion GO:0007269 2 0.017
negative regulation of synapse assembly GO:0051964 2 0.017
regulation of cellular amine metabolic process GO:0033238 0 0.016
regulation of membrane potential GO:0042391 23 0.016
regulation of protein catabolic process GO:0042176 1 0.016
cell death GO:0008219 121 0.016
gtp metabolic process GO:0046039 4 0.016
cellular response to starvation GO:0009267 1 0.016
protein complex disassembly GO:0043241 1 0.016
establishment of protein localization to organelle GO:0072594 4 0.016
regulation of purine nucleotide metabolic process GO:1900542 17 0.016
regulation of neurotransmitter secretion GO:0046928 1 0.016
monovalent inorganic cation transport GO:0015672 42 0.016
positive regulation of cytokine production GO:0001819 2 0.016
response to superoxide GO:0000303 2 0.016
cellular response to oxygen levels GO:0071453 1 0.015
regulation of localization GO:0032879 104 0.015
response to monosaccharide GO:0034284 3 0.015
negative regulation of nucleotide metabolic process GO:0045980 7 0.015
protein import GO:0017038 3 0.015
protein depolymerization GO:0051261 1 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.015
camp metabolic process GO:0046058 11 0.015
negative regulation of cellular process GO:0048523 283 0.015
positive regulation of cell adhesion GO:0045785 1 0.015
purine nucleotide biosynthetic process GO:0006164 20 0.015
sequestering of metal ion GO:0051238 3 0.015
cell substrate junction assembly GO:0007044 2 0.015
response to endogenous stimulus GO:0009719 83 0.015
transmission of nerve impulse GO:0019226 19 0.015
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 5 0.015
intracellular mrna localization GO:0008298 1 0.015
regulation of blood vessel size GO:0050880 2 0.015
regulation of hormone secretion GO:0046883 2 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
regulation of organelle assembly GO:1902115 4 0.014
regulation of blood circulation GO:1903522 32 0.014
response to decreased oxygen levels GO:0036293 25 0.014
gene expression GO:0010467 252 0.014
cellular response to extracellular stimulus GO:0031668 2 0.014
positive regulation of cellular catabolic process GO:0031331 3 0.014
nucleoside phosphate metabolic process GO:0006753 28 0.014
maternal determination of anterior posterior axis embryo GO:0008358 4 0.014
cellular response to lipid GO:0071396 39 0.014
negative regulation of chemotaxis GO:0050922 4 0.014
organelle fusion GO:0048284 3 0.014
positive regulation of camp metabolic process GO:0030816 2 0.014
locomotory behavior GO:0007626 34 0.014
cytosolic calcium ion transport GO:0060401 3 0.014
macromolecule biosynthetic process GO:0009059 227 0.014
regulation of gene expression GO:0010468 265 0.014
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.014
positive regulation of signaling GO:0023056 56 0.014
cell cell signaling GO:0007267 52 0.014
regulation of filopodium assembly GO:0051489 2 0.014
steroid hormone mediated signaling pathway GO:0043401 9 0.013
negative regulation of sequestering of calcium ion GO:0051283 4 0.013
regulation of cell substrate adhesion GO:0010810 1 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.013
macromolecular complex subunit organization GO:0043933 74 0.013
nuclear transport GO:0051169 4 0.013
microtubule depolymerization GO:0007019 1 0.013
carbohydrate biosynthetic process GO:0016051 1 0.013
protein localization to nucleus GO:0034504 3 0.013
mitochondrial transport GO:0006839 2 0.013
regulation of tube size GO:0035150 2 0.013
central nervous system development GO:0007417 387 0.013
negative regulation of protein complex assembly GO:0031333 1 0.013
negative regulation of secretion by cell GO:1903531 2 0.013
positive regulation of gtpase activity GO:0043547 1 0.013
positive regulation of lipid metabolic process GO:0045834 1 0.013
regulation of inflammatory response GO:0050727 2 0.013
negative regulation of cell communication GO:0010648 96 0.013
anterior posterior pattern specification GO:0009952 152 0.013
head development GO:0060322 303 0.013
regulation of protein complex disassembly GO:0043244 1 0.013
regulation of cell projection assembly GO:0060491 4 0.013
negative regulation of intracellular protein transport GO:0090317 3 0.013
modification dependent macromolecule catabolic process GO:0043632 3 0.013
single organism transport GO:0044765 206 0.012
meiotic nuclear division GO:0007126 4 0.012
negative regulation of cyclase activity GO:0031280 6 0.012
regulation of circadian rhythm GO:0042752 4 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
rna localization GO:0006403 4 0.012
negative regulation of macromolecule metabolic process GO:0010605 76 0.012
circulatory system process GO:0003013 87 0.012
ubiquitin dependent protein catabolic process GO:0006511 3 0.012
forebrain cell migration GO:0021885 1 0.012
regulation of purine nucleotide catabolic process GO:0033121 2 0.012
regulation of endocrine process GO:0044060 2 0.012
catecholamine biosynthetic process GO:0042423 2 0.012
circadian sleep wake cycle sleep GO:0050802 1 0.012
cyclic purine nucleotide metabolic process GO:0052652 18 0.012
regulation of locomotion GO:0040012 55 0.012
erk1 and erk2 cascade GO:0070371 4 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
nitric oxide metabolic process GO:0046209 2 0.012
regulation of cell activation GO:0050865 1 0.012
response to amine GO:0014075 1 0.012
organelle transport along microtubule GO:0072384 1 0.012
aging GO:0007568 2 0.012
negative regulation of neutrophil chemotaxis GO:0090024 3 0.012
positive regulation of biological process GO:0048518 253 0.012
calcium ion transport into cytosol GO:0060402 3 0.011
spinal cord development GO:0021510 46 0.011
protein complex subunit organization GO:0071822 46 0.011
response to alkaloid GO:0043279 2 0.011
protein dephosphorylation GO:0006470 3 0.011
centrosome cycle GO:0007098 1 0.011
cell part morphogenesis GO:0032990 246 0.011
regulation of system process GO:0044057 40 0.011
cytoplasm organization GO:0007028 4 0.011
dopamine biosynthetic process GO:0042416 2 0.011
organism emergence from protective structure GO:0071684 4 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
autophagy GO:0006914 4 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 5 0.011
negative regulation of cytokine production GO:0001818 1 0.011
peptidyl serine phosphorylation GO:0018105 1 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.011
actin filament based process GO:0030029 64 0.011
regulation of phosphate metabolic process GO:0019220 43 0.011
regulation of fatty acid metabolic process GO:0019217 1 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
embryo development ending in birth or egg hatching GO:0009792 271 0.011
negative regulation of multi organism process GO:0043901 3 0.011
calcium ion transmembrane transport GO:0070588 13 0.011
cellular protein catabolic process GO:0044257 4 0.011
regulation of muscle contraction GO:0006937 3 0.011
regulation of oocyte development GO:0060281 3 0.011
regulation of nucleoside metabolic process GO:0009118 2 0.011
response to wounding GO:0009611 116 0.011
regulation of ph GO:0006885 3 0.011
negative regulation of catabolic process GO:0009895 3 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.010
heart process GO:0003015 71 0.010
response to estrogen GO:0043627 27 0.010
response to hydrogen peroxide GO:0042542 3 0.010
transmembrane transport GO:0055085 120 0.010
positive regulation of secretion by cell GO:1903532 1 0.010
cell migration GO:0016477 237 0.010
pole plasm assembly GO:0007315 4 0.010
regulation of cellular component organization GO:0051128 86 0.010
positive regulation of apoptotic signaling pathway GO:2001235 1 0.010
cellular response to peptide hormone stimulus GO:0071375 5 0.010
regulation of microtubule cytoskeleton organization GO:0070507 3 0.010
response to oxygen radical GO:0000305 2 0.010
cellular component biogenesis GO:0044085 178 0.010
positive regulation of catalytic activity GO:0043085 25 0.010
response to abiotic stimulus GO:0009628 122 0.010
mitochondrion organization GO:0007005 4 0.010
negative regulation of metabolic process GO:0009892 86 0.010
embryonic organ morphogenesis GO:0048562 274 0.010
insulin like growth factor receptor signaling pathway GO:0048009 4 0.010
phosphate containing compound metabolic process GO:0006796 108 0.010
membrane invagination GO:0010324 1 0.010

pmch disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.019
disease of metabolism DOID:0014667 0 0.011
disease of cellular proliferation DOID:14566 0 0.010