Danio rerio

0 known processes

polr2a

polymerase (RNA) II (DNA directed) polypeptide A

(Aliases: im:7136071)

polr2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular nitrogen compound metabolic process GO:0034641 290 0.228
meiotic chromosome segregation GO:0045132 3 0.180
cellular component assembly GO:0022607 170 0.178
cellular component biogenesis GO:0044085 178 0.176
sensory organ development GO:0007423 393 0.154
signal transduction GO:0007165 455 0.135
cognition GO:0050890 1 0.132
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.131
hemopoiesis GO:0030097 183 0.123
regulation of organelle assembly GO:1902115 4 0.121
immune system development GO:0002520 191 0.117
immune system process GO:0002376 241 0.116
single organism organelle organization GO:1902589 199 0.115
determination of bilateral symmetry GO:0009855 204 0.110
translational initiation GO:0006413 3 0.101
cellular component movement GO:0006928 335 0.098
blood vessel morphogenesis GO:0048514 216 0.095
negative regulation of cellular process GO:0048523 283 0.092
nucleocytoplasmic transport GO:0006913 4 0.090
maintenance of location GO:0051235 4 0.087
organelle organization GO:0006996 227 0.085
protein import GO:0017038 3 0.085
spindle assembly GO:0051225 2 0.084
meiosis i GO:0007127 1 0.081
regulation of nucleocytoplasmic transport GO:0046822 2 0.081
peptide transport GO:0015833 1 0.080
embryonic organ development GO:0048568 381 0.077
regulation of translational initiation GO:0006446 1 0.076
gene expression GO:0010467 252 0.072
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.072
embryo development ending in birth or egg hatching GO:0009792 271 0.072
regulation of synaptic plasticity GO:0048167 1 0.072
nuclear transport GO:0051169 4 0.071
specification of symmetry GO:0009799 204 0.070
cell migration GO:0016477 237 0.070
regulation of intracellular protein transport GO:0033157 3 0.069
heterocycle metabolic process GO:0046483 290 0.068
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.068
cell motility GO:0048870 244 0.067
multicellular organism growth GO:0035264 4 0.067
regulation of multicellular organism growth GO:0040014 4 0.065
oocyte anterior posterior axis specification GO:0007314 4 0.065
protein dephosphorylation GO:0006470 3 0.064
macromolecule biosynthetic process GO:0009059 227 0.064
regulation of protein targeting GO:1903533 2 0.064
camera type eye development GO:0043010 222 0.063
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.063
meiotic cell cycle process GO:1903046 3 0.063
positive regulation of biological process GO:0048518 253 0.063
mesoderm development GO:0007498 88 0.060
locomotor rhythm GO:0045475 3 0.060
positive regulation of transport GO:0051050 2 0.058
positive regulation of cellular catabolic process GO:0031331 3 0.057
cellular amide metabolic process GO:0043603 4 0.056
tube morphogenesis GO:0035239 349 0.056
cellular response to nutrient levels GO:0031669 2 0.054
cellular macromolecule metabolic process GO:0044260 391 0.054
negative regulation of biological process GO:0048519 304 0.053
regulation of signal transduction GO:0009966 225 0.053
regulation of biological quality GO:0065008 263 0.052
cytokinesis GO:0000910 3 0.052
pole plasm assembly GO:0007315 4 0.052
chordate embryonic development GO:0043009 271 0.051
developmental growth GO:0048589 166 0.051
regulation of gene expression GO:0010468 265 0.051
steroid hormone secretion GO:0035929 1 0.050
germ line stem cell division GO:0042078 1 0.050
meiotic nuclear division GO:0007126 4 0.049
stem cell maintenance GO:0019827 4 0.048
regulation of establishment of protein localization GO:0070201 4 0.046
regulation of signaling GO:0023051 235 0.046
hormone secretion GO:0046879 2 0.046
digestive tract development GO:0048565 265 0.045
retina development in camera type eye GO:0060041 146 0.045
skeletal system development GO:0001501 181 0.045
establishment of protein localization to organelle GO:0072594 4 0.045
intracellular signal transduction GO:0035556 85 0.045
cellular modified amino acid metabolic process GO:0006575 3 0.044
organelle assembly GO:0070925 110 0.044
embryonic cranial skeleton morphogenesis GO:0048701 90 0.044
mitotic cell cycle process GO:1903047 48 0.043
mitotic cell cycle GO:0000278 64 0.043
angiogenesis GO:0001525 158 0.042
regulation of protein transport GO:0051223 3 0.042
nitrogen compound metabolic process GO:0006807 319 0.042
regulation of multicellular organismal process GO:0051239 277 0.042
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.042
synaptic vesicle localization GO:0097479 1 0.042
organism emergence from protective structure GO:0071684 4 0.041
maternal determination of anterior posterior axis embryo GO:0008358 4 0.041
regulation of nitrogen compound metabolic process GO:0051171 251 0.041
negative regulation of signaling GO:0023057 96 0.041
cartilage development GO:0051216 96 0.040
protein import into nucleus GO:0006606 3 0.040
heterocycle biosynthetic process GO:0018130 215 0.040
skeletal system morphogenesis GO:0048705 102 0.039
synaptic vesicle transport GO:0048489 1 0.039
cellular response to extracellular stimulus GO:0031668 2 0.039
regulation of binding GO:0051098 3 0.039
eye development GO:0001654 277 0.039
modification dependent macromolecule catabolic process GO:0043632 3 0.039
regulation of synapse organization GO:0050807 3 0.039
macromolecular complex subunit organization GO:0043933 74 0.039
fin regeneration GO:0031101 51 0.038
positive regulation of signal transduction GO:0009967 56 0.037
organic cyclic compound metabolic process GO:1901360 301 0.036
circadian regulation of gene expression GO:0032922 8 0.036
blood vessel development GO:0001568 246 0.036
transcription from rna polymerase ii promoter GO:0006366 80 0.036
epithelial tube morphogenesis GO:0060562 148 0.036
organic substance biosynthetic process GO:1901576 289 0.035
negative regulation of cytoplasmic transport GO:1903650 2 0.035
regulation of macromolecule biosynthetic process GO:0010556 225 0.035
regulation of circadian rhythm GO:0042752 4 0.035
nucleic acid templated transcription GO:0097659 181 0.035
regulation of stem cell differentiation GO:2000736 4 0.035
single organism nuclear import GO:1902593 3 0.035
regulation of mrna processing GO:0050684 3 0.035
locomotion GO:0040011 313 0.034
positive regulation of cellular component biogenesis GO:0044089 3 0.034
regulation of cell communication GO:0010646 232 0.034
regulation of cytoplasmic transport GO:1903649 4 0.034
localization of cell GO:0051674 244 0.034
cell surface receptor signaling pathway GO:0007166 325 0.034
response to biotic stimulus GO:0009607 97 0.033
biosynthetic process GO:0009058 294 0.033
aging GO:0007568 2 0.033
nuclear import GO:0051170 3 0.033
cell cycle GO:0007049 93 0.033
regulation of reproductive process GO:2000241 4 0.032
anterior posterior pattern specification GO:0009952 152 0.032
hematopoietic or lymphoid organ development GO:0048534 191 0.032
cellular macromolecule biosynthetic process GO:0034645 224 0.032
apoptotic process GO:0006915 116 0.032
positive regulation of cell communication GO:0010647 56 0.032
negative regulation of intracellular transport GO:0032387 3 0.031
regulation of dna templated transcription elongation GO:0032784 3 0.031
rna transport GO:0050658 2 0.031
larval development GO:0002164 2 0.031
regulation of protein localization to nucleus GO:1900180 2 0.031
rna metabolic process GO:0016070 219 0.030
gastrulation with mouth forming second GO:0001702 44 0.030
internal peptidyl lysine acetylation GO:0018393 2 0.030
determination of heart left right asymmetry GO:0061371 117 0.030
regulation of response to biotic stimulus GO:0002831 2 0.030
morphogenesis of an epithelium GO:0002009 333 0.030
response to radiation GO:0009314 51 0.030
female meiotic division GO:0007143 2 0.030
positive regulation of secretion by cell GO:1903532 1 0.030
positive regulation of catabolic process GO:0009896 4 0.030
response to other organism GO:0051707 97 0.030
negative regulation of signal transduction GO:0009968 94 0.030
specification of organ identity GO:0010092 2 0.030
cell division GO:0051301 20 0.029
spindle assembly involved in meiosis GO:0090306 1 0.029
multi organism reproductive process GO:0044703 36 0.029
macromolecular complex assembly GO:0065003 35 0.029
determination of left right symmetry GO:0007368 179 0.029
regulation of cellular biosynthetic process GO:0031326 245 0.028
regulation of oligodendrocyte differentiation GO:0048713 1 0.028
regulation of transcription dna templated GO:0006355 213 0.028
convergent extension GO:0060026 118 0.028
positive regulation of cell division GO:0051781 2 0.028
internal protein amino acid acetylation GO:0006475 2 0.028
programmed cell death GO:0012501 119 0.028
germ line stem cell maintenance GO:0030718 2 0.027
regulation of cell differentiation GO:0045595 142 0.027
defense response GO:0006952 47 0.027
protein acylation GO:0043543 3 0.027
embryonic skeletal joint development GO:0072498 3 0.027
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.026
purine nucleoside monophosphate catabolic process GO:0009128 4 0.026
dicarboxylic acid transport GO:0006835 1 0.026
calcium ion import GO:0070509 4 0.026
nucleic acid transport GO:0050657 2 0.026
meiotic spindle organization GO:0000212 1 0.026
erk1 and erk2 cascade GO:0070371 4 0.026
neuron differentiation GO:0030182 353 0.025
protein localization to nucleus GO:0034504 3 0.025
positive regulation of exocytosis GO:0045921 1 0.025
tissue remodeling GO:0048771 4 0.025
rna modification GO:0009451 2 0.025
ncrna metabolic process GO:0034660 12 0.025
response to external stimulus GO:0009605 264 0.025
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.025
protein localization GO:0008104 40 0.025
regulation of cytokine production GO:0001817 3 0.025
regulation of protein ubiquitination GO:0031396 3 0.024
regulation of glial cell differentiation GO:0045685 4 0.024
dna templated transcription elongation GO:0006354 3 0.024
regulation of developmental process GO:0050793 247 0.024
ion transport GO:0006811 114 0.024
atp catabolic process GO:0006200 4 0.024
regulation of jak stat cascade GO:0046425 3 0.024
ubiquitin dependent protein catabolic process GO:0006511 3 0.023
regulation of receptor activity GO:0010469 2 0.023
stem cell differentiation GO:0048863 117 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.023
regulation of nucleoside metabolic process GO:0009118 2 0.023
negative regulation of protein transport GO:0051224 3 0.023
cytoskeleton organization GO:0007010 96 0.023
negative regulation of intracellular protein transport GO:0090317 3 0.023
proximal distal pattern formation GO:0009954 1 0.023
cellular macromolecule localization GO:0070727 21 0.023
regulation of production of molecular mediator of immune response GO:0002700 1 0.023
positive regulation of cellular process GO:0048522 201 0.022
regulation of protein import into nucleus GO:0042306 2 0.022
transcription elongation from rna polymerase ii promoter GO:0006368 3 0.022
gtp catabolic process GO:0006184 2 0.022
negative regulation of protein phosphorylation GO:0001933 4 0.022
gastrulation GO:0007369 208 0.022
regulation of response to stimulus GO:0048583 269 0.022
embryonic skeletal system morphogenesis GO:0048704 93 0.022
regulation of multicellular organismal development GO:2000026 223 0.022
peptidyl serine modification GO:0018209 2 0.022
chromosome organization GO:0051276 31 0.022
single organism transport GO:0044765 206 0.022
hatching GO:0035188 4 0.022
pyruvate metabolic process GO:0006090 1 0.022
regulation of nucleotide catabolic process GO:0030811 2 0.021
response to chemical GO:0042221 320 0.021
regulation of meiotic cell cycle GO:0051445 1 0.021
multicellular organismal reproductive process GO:0048609 35 0.021
ribosome assembly GO:0042255 1 0.021
positive regulation of glial cell differentiation GO:0045687 1 0.021
embryonic skeletal system development GO:0048706 97 0.021
cell cycle g1 s phase transition GO:0044843 1 0.021
cellular nitrogen compound biosynthetic process GO:0044271 218 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
entrainment of circadian clock GO:0009649 2 0.020
spermatid differentiation GO:0048515 2 0.020
regulation of metabolic process GO:0019222 359 0.020
negative regulation of nuclear division GO:0051784 3 0.020
peptidyl serine phosphorylation GO:0018105 1 0.020
generation of neurons GO:0048699 385 0.020
ribosomal small subunit biogenesis GO:0042274 2 0.020
positive regulation of notch signaling pathway GO:0045747 3 0.020
negative regulation of protein kinase activity GO:0006469 4 0.020
embryonic organ morphogenesis GO:0048562 274 0.020
positive regulation of secretion GO:0051047 1 0.020
cellular transition metal ion homeostasis GO:0046916 3 0.020
negative regulation of mapk cascade GO:0043409 4 0.020
macromolecule localization GO:0033036 54 0.020
cell matrix adhesion GO:0007160 4 0.020
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.020
regulation of dna recombination GO:0000018 2 0.020
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.020
death GO:0016265 121 0.020
pancreas development GO:0031016 84 0.020
spliceosomal snrnp assembly GO:0000387 2 0.020
primitive hemopoiesis GO:0060215 27 0.020
positive regulation of muscle cell differentiation GO:0051149 1 0.020
negative regulation of defense response GO:0031348 2 0.020
mitochondrion organization GO:0007005 4 0.020
ribonucleoprotein complex assembly GO:0022618 5 0.020
exocytosis GO:0006887 1 0.019
nucleic acid metabolic process GO:0090304 244 0.019
foregut morphogenesis GO:0007440 4 0.019
negative regulation of cellular catabolic process GO:0031330 3 0.019
determination of ventral identity GO:0048264 21 0.019
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.019
response to unfolded protein GO:0006986 2 0.019
protein targeting to nucleus GO:0044744 3 0.019
vasculature development GO:0001944 278 0.019
transport GO:0006810 220 0.018
membrane invagination GO:0010324 1 0.018
cellular response to starvation GO:0009267 1 0.018
development of primary female sexual characteristics GO:0046545 4 0.018
intracellular receptor signaling pathway GO:0030522 30 0.018
camera type eye morphogenesis GO:0048593 108 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
adult behavior GO:0030534 2 0.018
negative regulation of catabolic process GO:0009895 3 0.018
cellular response to external stimulus GO:0071496 2 0.018
regulation of cell division GO:0051302 12 0.017
negative regulation of wnt signaling pathway GO:0030178 30 0.017
extrinsic apoptotic signaling pathway GO:0097191 3 0.017
positive regulation of apoptotic signaling pathway GO:2001235 1 0.017
positive regulation of response to stimulus GO:0048584 80 0.017
positive regulation of transcription dna templated GO:0045893 57 0.017
myeloid cell differentiation GO:0030099 86 0.017
positive regulation of cell cycle GO:0045787 3 0.017
regulation of apoptotic process GO:0042981 98 0.017
sister chromatid cohesion GO:0007062 2 0.017
proteasomal protein catabolic process GO:0010498 2 0.017
nucleobase containing compound metabolic process GO:0006139 274 0.017
positive regulation of myeloid cell differentiation GO:0045639 2 0.017
female sex differentiation GO:0046660 4 0.017
stem cell development GO:0048864 82 0.017
golgi vesicle transport GO:0048193 3 0.017
regulation of cellular metabolic process GO:0031323 320 0.017
embryonic skeletal joint morphogenesis GO:0060272 3 0.017
synaptic growth at neuromuscular junction GO:0051124 2 0.017
regulation of epithelial to mesenchymal transition GO:0010717 3 0.017
cell death GO:0008219 121 0.017
regulation of exocytosis GO:0017157 1 0.017
response to topologically incorrect protein GO:0035966 2 0.017
g1 s transition of mitotic cell cycle GO:0000082 1 0.017
amino acid transport GO:0006865 2 0.017
neurotransmitter secretion GO:0007269 2 0.017
cellular biosynthetic process GO:0044249 286 0.016
amide biosynthetic process GO:0043604 1 0.016
endocrine hormone secretion GO:0060986 2 0.016
b cell activation GO:0042113 2 0.016
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.016
chromosome organization involved in meiosis GO:0070192 1 0.016
neuron projection guidance GO:0097485 86 0.016
regulation of erk1 and erk2 cascade GO:0070372 4 0.016
regulation of histone methylation GO:0031060 3 0.016
neurotransmitter transport GO:0006836 2 0.016
negative regulation of kinase activity GO:0033673 4 0.016
ovulation cycle process GO:0022602 2 0.016
response to endogenous stimulus GO:0009719 83 0.016
response to alkaloid GO:0043279 2 0.016
regulation of mrna splicing via spliceosome GO:0048024 3 0.016
renal tubule morphogenesis GO:0061333 1 0.016
establishment of localization GO:0051234 244 0.016
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.016
regulation of cellular component organization GO:0051128 86 0.016
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.016
establishment of rna localization GO:0051236 3 0.016
regulation of steroid hormone secretion GO:2000831 1 0.016
secondary metabolic process GO:0019748 3 0.016
regulation of gtp catabolic process GO:0033124 2 0.016
nucleobase containing compound transport GO:0015931 2 0.016
organic cyclic compound biosynthetic process GO:1901362 223 0.016
behavior GO:0007610 74 0.016
negative regulation of myeloid cell differentiation GO:0045638 1 0.016
tissue regeneration GO:0042246 74 0.016
central nervous system neuron differentiation GO:0021953 74 0.016
somitogenesis GO:0001756 87 0.015
cytoskeleton dependent cytokinesis GO:0061640 3 0.015
microtubule polymerization GO:0046785 2 0.015
synaptic vesicle endocytosis GO:0048488 1 0.015
hormone transport GO:0009914 2 0.015
determination of dorsal ventral asymmetry GO:0048262 34 0.015
negative regulation of multicellular organismal process GO:0051241 69 0.015
intracellular mrna localization GO:0008298 1 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.015
establishment of endothelial barrier GO:0061028 3 0.015
cytoplasm organization GO:0007028 4 0.015
wound healing GO:0042060 90 0.015
antimicrobial humoral response GO:0019730 2 0.015
neuroblast proliferation GO:0007405 2 0.015
ribonucleoprotein complex biogenesis GO:0022613 13 0.015
hepaticobiliary system development GO:0061008 98 0.015
response to stress GO:0006950 263 0.015
rna localization GO:0006403 4 0.015
cell cycle process GO:0022402 53 0.015
regulation of cell death GO:0010941 103 0.014
cellular response to organic substance GO:0071310 105 0.014
production of molecular mediator of immune response GO:0002440 2 0.014
negative regulation of mitosis GO:0045839 3 0.014
positive regulation of neural precursor cell proliferation GO:2000179 1 0.014
protein trimerization GO:0070206 4 0.014
amine metabolic process GO:0009308 2 0.014
cell substrate adhesion GO:0031589 4 0.014
phagocytosis GO:0006909 3 0.014
regulation of protein complex assembly GO:0043254 3 0.014
embryonic viscerocranium morphogenesis GO:0048703 52 0.014
neuronal stem cell maintenance GO:0097150 2 0.014
mrna transport GO:0051028 2 0.014
embryonic hemopoiesis GO:0035162 53 0.014
response to uv GO:0009411 3 0.014
l amino acid transport GO:0015807 1 0.014
response to abiotic stimulus GO:0009628 122 0.014
negative regulation of developmental process GO:0051093 65 0.014
multi organism process GO:0051704 134 0.014
regulation of cellular protein catabolic process GO:1903362 1 0.014
cellular protein modification process GO:0006464 100 0.014
regulation of dendrite morphogenesis GO:0048814 3 0.014
digestive tract morphogenesis GO:0048546 231 0.014
gtp metabolic process GO:0046039 4 0.014
innate immune response GO:0045087 13 0.014
regulation of rna biosynthetic process GO:2001141 213 0.014
regulation of rna metabolic process GO:0051252 224 0.014
regulation of wnt signaling pathway GO:0030111 53 0.014
protein polymerization GO:0051258 4 0.014
regulation of gene silencing GO:0060968 1 0.013
regulation of intracellular signal transduction GO:1902531 57 0.013
mononuclear cell proliferation GO:0032943 1 0.013
response to light stimulus GO:0009416 46 0.013
regulation of transporter activity GO:0032409 2 0.013
central nervous system development GO:0007417 387 0.013
dna modification GO:0006304 8 0.013
membrane fusion GO:0061025 2 0.013
cell projection organization GO:0030030 284 0.013
dna methylation GO:0006306 8 0.013
g2 dna damage checkpoint GO:0031572 3 0.013
negative regulation of protein localization to nucleus GO:1900181 2 0.013
peptidyl threonine modification GO:0018210 1 0.013
iron ion homeostasis GO:0055072 4 0.013
regulation of protein catabolic process GO:0042176 1 0.013
mitotic sister chromatid segregation GO:0000070 6 0.013
centrosome organization GO:0051297 1 0.013
regulation of gene expression epigenetic GO:0040029 11 0.013
regulation of mesenchymal cell proliferation GO:0010464 1 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
centrosome cycle GO:0007098 1 0.013
regulation of metal ion transport GO:0010959 4 0.013
cellular response to unfolded protein GO:0034620 2 0.013
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.013
female gonad development GO:0008585 4 0.013
monocyte differentiation GO:0030224 2 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
connective tissue development GO:0061448 99 0.013
vesicle localization GO:0051648 27 0.013
forebrain regionalization GO:0021871 4 0.013
nephron tubule morphogenesis GO:0072078 1 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.012
nuclear export GO:0051168 1 0.012
aromatic compound biosynthetic process GO:0019438 217 0.012
response to growth factor GO:0070848 39 0.012
positive regulation of immune effector process GO:0002699 3 0.012
regulation of protein binding GO:0043393 3 0.012
cell part morphogenesis GO:0032990 246 0.012
oligodendrocyte differentiation GO:0048709 23 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.012
negative regulation of chromosome organization GO:2001251 1 0.012
establishment of synaptic vesicle localization GO:0097480 1 0.012
covalent chromatin modification GO:0016569 20 0.012
positive regulation of chromatin modification GO:1903310 1 0.012
spindle assembly involved in female meiosis GO:0007056 1 0.012
calcium ion dependent exocytosis GO:0017156 1 0.012
response to hexose GO:0009746 3 0.012
alternative mrna splicing via spliceosome GO:0000380 1 0.012
histone h3 k4 methylation GO:0051568 2 0.012
negative regulation of translational initiation GO:0045947 1 0.012
protein complex subunit organization GO:0071822 46 0.012
regulation of cell activation GO:0050865 1 0.012
regulation of lipid transport GO:0032368 4 0.012
modification dependent protein catabolic process GO:0019941 3 0.012
positive regulation of lymphocyte mediated immunity GO:0002708 1 0.012
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.012
optic placode formation GO:0001743 4 0.012
cellular protein catabolic process GO:0044257 4 0.012
glucose homeostasis GO:0042593 1 0.012
response to carbohydrate GO:0009743 3 0.012
convergent extension involved in axis elongation GO:0060028 26 0.012
phagocytosis engulfment GO:0006911 1 0.012
cellular response to topologically incorrect protein GO:0035967 2 0.012
leukocyte proliferation GO:0070661 1 0.012
negative regulation of rna splicing GO:0033119 1 0.012
peptide metabolic process GO:0006518 1 0.012
regulation of endocrine process GO:0044060 2 0.012
negative regulation of cell communication GO:0010648 96 0.012
positive regulation of gene expression GO:0010628 71 0.012
nucleobase containing compound biosynthetic process GO:0034654 205 0.011
regulation of oxidative stress induced cell death GO:1903201 2 0.011
nephron epithelium morphogenesis GO:0072088 1 0.011
formation of primary germ layer GO:0001704 62 0.011
system process GO:0003008 185 0.011
regulation of macromolecule metabolic process GO:0060255 317 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
positive regulation of stem cell proliferation GO:2000648 1 0.011
endoplasmic reticulum unfolded protein response GO:0030968 2 0.011
positive regulation of dna templated transcription elongation GO:0032786 1 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.011
spliceosomal complex assembly GO:0000245 1 0.011
peptidyl tyrosine dephosphorylation GO:0035335 1 0.011
response to external biotic stimulus GO:0043207 97 0.011
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.011
microtubule cytoskeleton organization GO:0000226 33 0.011
response to organic substance GO:0010033 153 0.011
er to golgi vesicle mediated transport GO:0006888 1 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
wnt signaling pathway GO:0016055 80 0.011
adherens junction organization GO:0034332 4 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
rna biosynthetic process GO:0032774 181 0.011
cell type specific apoptotic process GO:0097285 22 0.011
axon guidance GO:0007411 86 0.011
growth GO:0040007 174 0.011
positive regulation of cell activation GO:0050867 1 0.011
hard palate development GO:0060022 4 0.011
post embryonic organ development GO:0048569 4 0.011
cell substrate junction assembly GO:0007044 2 0.011
neuron development GO:0048666 262 0.011
desmosome assembly GO:0002159 2 0.011
response to monosaccharide GO:0034284 3 0.011
branching morphogenesis of an epithelial tube GO:0048754 15 0.011
carbohydrate homeostasis GO:0033500 1 0.011
cell projection morphogenesis GO:0048858 244 0.011
ovulation cycle GO:0042698 2 0.011
response to metal ion GO:0010038 34 0.011
regulation of hormone levels GO:0010817 21 0.011
organic substance transport GO:0071702 58 0.011

polr2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.019
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
organ system cancer DOID:0050686 0 0.019
disease of anatomical entity DOID:7 0 0.018
muscular disease DOID:0080000 0 0.016
musculoskeletal system disease DOID:17 0 0.016
muscle tissue disease DOID:66 0 0.016
large intestine cancer DOID:5672 0 0.012
gastrointestinal system cancer DOID:3119 0 0.012
intestinal cancer DOID:10155 0 0.012
colorectal cancer DOID:9256 0 0.012