Danio rerio

46 known processes

polr3b

polymerase (RNA) III (DNA directed) polypeptide B

(Aliases: si:dkey-103i16.3,wu:fc20h06)

polr3b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.906
Worm
cellular aromatic compound metabolic process GO:0006725 295 0.426
gene expression GO:0010467 252 0.402
rna metabolic process GO:0016070 219 0.319
cellular macromolecule metabolic process GO:0044260 391 0.282
organelle organization GO:0006996 227 0.201
nitrogen compound metabolic process GO:0006807 319 0.177
cellular macromolecule biosynthetic process GO:0034645 224 0.169
organic substance biosynthetic process GO:1901576 289 0.166
locomotion GO:0040011 313 0.165
nucleic acid metabolic process GO:0090304 244 0.153
heterocycle metabolic process GO:0046483 290 0.149
nucleobase containing compound metabolic process GO:0006139 274 0.147
mitochondrion organization GO:0007005 4 0.142
digestive tract development GO:0048565 265 0.127
maintenance of location GO:0051235 4 0.113
organonitrogen compound metabolic process GO:1901564 74 0.109
establishment of protein localization to organelle GO:0072594 4 0.108
cellular nitrogen compound metabolic process GO:0034641 290 0.104
organelle assembly GO:0070925 110 0.103
macromolecule biosynthetic process GO:0009059 227 0.102
spindle assembly GO:0051225 2 0.099
regulation of gene expression GO:0010468 265 0.094
oxoacid metabolic process GO:0043436 31 0.094
response to chemical GO:0042221 320 0.093
transport GO:0006810 220 0.091
tube morphogenesis GO:0035239 349 0.091
regulation of biological quality GO:0065008 263 0.091
aging GO:0007568 2 0.089
hepaticobiliary system development GO:0061008 98 0.087
carboxylic acid metabolic process GO:0019752 22 0.085
digestive system development GO:0055123 289 0.085
cellular amino acid metabolic process GO:0006520 7 0.080
translational initiation GO:0006413 3 0.079
cellular biosynthetic process GO:0044249 286 0.076
internal peptidyl lysine acetylation GO:0018393 2 0.076
nuclear transport GO:0051169 4 0.071
chordate embryonic development GO:0043009 271 0.067
regulation of biosynthetic process GO:0009889 250 0.062
regulation of developmental process GO:0050793 247 0.060
single organism metabolic process GO:0044710 217 0.059
cellular response to chemical stimulus GO:0070887 157 0.059
reproduction GO:0000003 40 0.057
Worm
embryo development ending in birth or egg hatching GO:0009792 271 0.057
Worm
protein metabolic process GO:0019538 183 0.057
meiotic cell cycle process GO:1903046 3 0.056
establishment of localization GO:0051234 244 0.055
protein import GO:0017038 3 0.055
gland development GO:0048732 143 0.053
multicellular organism growth GO:0035264 4 0.052
nuclear import GO:0051170 3 0.051
programmed cell death GO:0012501 119 0.051
Worm
spindle assembly involved in mitosis GO:0090307 1 0.048
liver development GO:0001889 96 0.047
cellular amine metabolic process GO:0044106 2 0.047
amine metabolic process GO:0009308 2 0.046
small molecule metabolic process GO:0044281 77 0.045
organic cyclic compound metabolic process GO:1901360 301 0.044
regulation of primary metabolic process GO:0080090 311 0.044
regulation of nitrogen compound metabolic process GO:0051171 251 0.044
meiotic nuclear division GO:0007126 4 0.042
regulation of cellular amine metabolic process GO:0033238 0 0.042
regulation of macromolecule biosynthetic process GO:0010556 225 0.042
negative regulation of macromolecule metabolic process GO:0010605 76 0.041
hematopoietic or lymphoid organ development GO:0048534 191 0.041
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.040
protein acylation GO:0043543 3 0.040
regulation of skeletal muscle tissue development GO:0048641 4 0.040
protein localization GO:0008104 40 0.040
ribosome assembly GO:0042255 1 0.040
stem cell maintenance GO:0019827 4 0.039
negative regulation of protein kinase activity GO:0006469 4 0.039
cytokinesis GO:0000910 3 0.039
heterocycle biosynthetic process GO:0018130 215 0.038
organic acid metabolic process GO:0006082 31 0.037
guanosine containing compound metabolic process GO:1901068 4 0.037
organic cyclic compound biosynthetic process GO:1901362 223 0.036
apoptotic process GO:0006915 116 0.036
Worm
positive regulation of cell cycle GO:0045787 3 0.035
immune system development GO:0002520 191 0.035
lipid storage GO:0019915 1 0.034
regulation of nucleic acid templated transcription GO:1903506 213 0.033
skeletal muscle organ development GO:0060538 78 0.033
response to stress GO:0006950 263 0.033
digestive tract morphogenesis GO:0048546 231 0.033
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.033
neuron differentiation GO:0030182 353 0.033
atp catabolic process GO:0006200 4 0.033
negative regulation of gene expression GO:0010629 65 0.032
biosynthetic process GO:0009058 294 0.032
positive regulation of cellular amine metabolic process GO:0033240 0 0.032
cellular protein metabolic process GO:0044267 129 0.032
meiotic chromosome segregation GO:0045132 3 0.031
cell migration GO:0016477 237 0.030
gtp catabolic process GO:0006184 2 0.030
cellular ketone metabolic process GO:0042180 11 0.030
aromatic compound biosynthetic process GO:0019438 217 0.030
microtubule organizing center organization GO:0031023 1 0.029
regulation of multicellular organismal development GO:2000026 223 0.029
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.029
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.029
protein complex disassembly GO:0043241 1 0.029
regulation of rna biosynthetic process GO:2001141 213 0.029
protein acetylation GO:0006473 2 0.029
cellular component disassembly GO:0022411 1 0.029
sensory organ development GO:0007423 393 0.028
regulation of cellular amino acid metabolic process GO:0006521 0 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.028
cellular nitrogen compound biosynthetic process GO:0044271 218 0.028
negative regulation of biological process GO:0048519 304 0.028
single organism nuclear import GO:1902593 3 0.028
guanosine containing compound catabolic process GO:1901069 2 0.028
regulation of multicellular organism growth GO:0040014 4 0.028
positive regulation of catabolic process GO:0009896 4 0.028
regulation of binding GO:0051098 3 0.028
regulation of macromolecule metabolic process GO:0060255 317 0.028
cellular component movement GO:0006928 335 0.027
negative regulation of cellular process GO:0048523 283 0.027
cell death GO:0008219 121 0.027
Worm
positive regulation of cellular catabolic process GO:0031331 3 0.027
regulation of protein targeting GO:1903533 2 0.027
regulation of intracellular protein transport GO:0033157 3 0.027
nucleic acid templated transcription GO:0097659 181 0.027
localization of cell GO:0051674 244 0.026
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.026
cellular component biogenesis GO:0044085 178 0.026
eye development GO:0001654 277 0.025
cell cycle GO:0007049 93 0.025
regulation of establishment of protein localization GO:0070201 4 0.025
cytoskeleton organization GO:0007010 96 0.025
muscle organ development GO:0007517 101 0.025
macromolecular complex subunit organization GO:0043933 74 0.024
regionalization GO:0003002 274 0.024
response to amino acid GO:0043200 2 0.024
regulation of protein import into nucleus GO:0042306 2 0.024
regulation of multicellular organismal process GO:0051239 277 0.024
embryonic organ development GO:0048568 381 0.024
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.024
zymogen activation GO:0031638 3 0.023
regulation of protein binding GO:0043393 3 0.023
vasculature development GO:0001944 278 0.023
regulation of cellular ketone metabolic process GO:0010565 7 0.023
negative regulation of kinase activity GO:0033673 4 0.023
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.023
regulation of nucleocytoplasmic transport GO:0046822 2 0.023
response to abiotic stimulus GO:0009628 122 0.023
proteasomal protein catabolic process GO:0010498 2 0.023
ribosomal small subunit biogenesis GO:0042274 2 0.023
developmental growth GO:0048589 166 0.022
response to organic substance GO:0010033 153 0.022
rna biosynthetic process GO:0032774 181 0.022
negative regulation of metabolic process GO:0009892 86 0.022
internal protein amino acid acetylation GO:0006475 2 0.022
protein import into nucleus GO:0006606 3 0.022
embryonic skeletal system morphogenesis GO:0048704 93 0.022
regulation of cellular protein metabolic process GO:0032268 52 0.022
macromolecule localization GO:0033036 54 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.021
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.021
adult behavior GO:0030534 2 0.021
determination of left right symmetry GO:0007368 179 0.021
regulation of transcription dna templated GO:0006355 213 0.021
transcription dna templated GO:0006351 181 0.021
embryonic skeletal system development GO:0048706 97 0.021
cell surface receptor signaling pathway GO:0007166 325 0.021
gtp metabolic process GO:0046039 4 0.020
microtubule based process GO:0007017 60 0.020
regulation of translational initiation GO:0006446 1 0.020
neuron projection development GO:0031175 180 0.020
positive regulation of biological process GO:0048518 253 0.020
protein localization to nucleus GO:0034504 3 0.020
centrosome organization GO:0051297 1 0.020
cell part morphogenesis GO:0032990 246 0.020
positive regulation of chromosome organization GO:2001252 1 0.019
nucleocytoplasmic transport GO:0006913 4 0.019
negative regulation of protein phosphorylation GO:0001933 4 0.019
single organism organelle organization GO:1902589 199 0.019
protein targeting to nucleus GO:0044744 3 0.019
protein modification process GO:0036211 100 0.019
peptidyl lysine acetylation GO:0018394 2 0.019
single organism localization GO:1902578 225 0.019
transcription from rna polymerase ii promoter GO:0006366 80 0.019
axonogenesis GO:0007409 152 0.018
single organism transport GO:0044765 206 0.018
microtubule polymerization or depolymerization GO:0031109 3 0.018
regulation of mitotic cell cycle GO:0007346 25 0.018
regulation of cellular biosynthetic process GO:0031326 245 0.018
positive regulation of transport GO:0051050 2 0.018
protein depolymerization GO:0051261 1 0.017
definitive hemopoiesis GO:0060216 18 0.017
regulation of organelle assembly GO:1902115 4 0.017
cell motility GO:0048870 244 0.017
regulation of nucleoside metabolic process GO:0009118 2 0.017
response to corticosteroid GO:0031960 1 0.017
regulation of mitochondrion organization GO:0010821 1 0.017
modification dependent protein catabolic process GO:0019941 3 0.017
cell cycle arrest GO:0007050 1 0.017
response to external stimulus GO:0009605 264 0.017
multi organism process GO:0051704 134 0.017
regulation of programmed cell death GO:0043067 101 0.017
cellular response to external stimulus GO:0071496 2 0.017
regulation of cysteine type endopeptidase activity GO:2000116 21 0.017
regulation of nucleotide catabolic process GO:0030811 2 0.017
intracellular signal transduction GO:0035556 85 0.016
gastrulation GO:0007369 208 0.016
mesenchyme development GO:0060485 127 0.016
response to carbohydrate GO:0009743 3 0.016
regulation of gtp catabolic process GO:0033124 2 0.016
regulation of cellular metabolic process GO:0031323 320 0.016
regulation of purine nucleotide catabolic process GO:0033121 2 0.016
somite development GO:0061053 96 0.016
ncrna metabolic process GO:0034660 12 0.016
negative regulation of myeloid cell differentiation GO:0045638 1 0.016
somitogenesis GO:0001756 87 0.016
cellular protein localization GO:0034613 20 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
regulation of organelle organization GO:0033043 29 0.015
protein maturation GO:0051604 12 0.015
synaptic transmission cholinergic GO:0007271 4 0.015
lateral line system development GO:0048925 76 0.015
cell morphogenesis GO:0000902 289 0.015
homeostatic process GO:0042592 142 0.015
rna processing GO:0006396 25 0.015
macromolecular complex assembly GO:0065003 35 0.015
interspecies interaction between organisms GO:0044419 4 0.015
centrosome cycle GO:0007098 1 0.015
regulation of cell differentiation GO:0045595 142 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
stem cell proliferation GO:0072089 4 0.015
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.015
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.015
negative regulation of cysteine type endopeptidase activity GO:2000117 8 0.015
histone h3 k4 methylation GO:0051568 2 0.014
cellular component morphogenesis GO:0032989 336 0.014
cellular macromolecular complex assembly GO:0034622 24 0.014
regulation of glucose transport GO:0010827 1 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.014
regulation of cytoplasmic transport GO:1903649 4 0.014
cellular protein catabolic process GO:0044257 4 0.014
regulation of myotube differentiation GO:0010830 2 0.014
growth GO:0040007 174 0.014
embryonic cranial skeleton morphogenesis GO:0048701 90 0.014
response to uv GO:0009411 3 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.014
regulation of gtpase activity GO:0043087 2 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
determination of bilateral symmetry GO:0009855 204 0.014
regulation of signal transduction GO:0009966 225 0.014
mitotic cell cycle GO:0000278 64 0.014
reproductive process GO:0022414 40 0.014
maturation of ssu rrna GO:0030490 1 0.014
positive regulation of camp metabolic process GO:0030816 2 0.014
morphogenesis of an epithelium GO:0002009 333 0.014
carbohydrate homeostasis GO:0033500 1 0.013
regulation of membrane potential GO:0042391 23 0.013
regulation of rna metabolic process GO:0051252 224 0.013
neuron development GO:0048666 262 0.013
sensory system development GO:0048880 76 0.013
macromolecular complex disassembly GO:0032984 1 0.013
macromolecule modification GO:0043412 111 0.013
posttranscriptional gene silencing GO:0016441 3 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
positive regulation of biosynthetic process GO:0009891 68 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.013
protein stabilization GO:0050821 2 0.013
positive regulation of developmental process GO:0051094 50 0.013
positive regulation of nucleotide catabolic process GO:0030813 1 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 9 0.012
reproductive structure development GO:0048608 5 0.012
positive regulation of nucleoside metabolic process GO:0045979 1 0.012
mrna metabolic process GO:0016071 20 0.012
striated muscle cell differentiation GO:0051146 129 0.012
specification of symmetry GO:0009799 204 0.012
ribonucleoside monophosphate catabolic process GO:0009158 4 0.012
negative regulation of apoptotic process GO:0043066 55 0.012
cell projection morphogenesis GO:0048858 244 0.012
regulation of molecular function GO:0065009 70 0.012
cellular response to organic substance GO:0071310 105 0.012
embryonic heart tube morphogenesis GO:0003143 108 0.012
multicellular organismal signaling GO:0035637 22 0.012
mesenchymal cell differentiation GO:0048762 87 0.012
cellular protein modification process GO:0006464 100 0.012
post embryonic development GO:0009791 7 0.012
Worm
nucleobase containing compound biosynthetic process GO:0034654 205 0.012
cytoskeleton dependent cytokinesis GO:0061640 3 0.012
central nervous system development GO:0007417 387 0.012
immune system process GO:0002376 241 0.012
pancreas development GO:0031016 84 0.011
positive regulation of cellular biosynthetic process GO:0031328 68 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
cell proliferation GO:0008283 80 0.011
neuron projection morphogenesis GO:0048812 161 0.011
mitotic recombination GO:0006312 2 0.011
cell cycle g1 s phase transition GO:0044843 1 0.011
smoothened signaling pathway GO:0007224 30 0.011
regulation of protein transport GO:0051223 3 0.011
developmental growth involved in morphogenesis GO:0060560 86 0.011
b cell activation GO:0042113 2 0.011
positive regulation of macromolecule metabolic process GO:0010604 93 0.011
posttranscriptional gene silencing by rna GO:0035194 3 0.011
regulation of peptidase activity GO:0052547 23 0.011
positive regulation of gtpase activity GO:0043547 1 0.011
brain development GO:0007420 293 0.011
skeletal muscle tissue development GO:0007519 67 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
regulation of purine nucleotide metabolic process GO:1900542 17 0.011
response to organic cyclic compound GO:0014070 51 0.011
posttranscriptional regulation of gene expression GO:0010608 14 0.011
rna modification GO:0009451 2 0.010
regulation of protein ubiquitination GO:0031396 3 0.010
anterior posterior pattern specification GO:0009952 152 0.010
regulation of anatomical structure morphogenesis GO:0022603 130 0.010
cellular protein complex disassembly GO:0043624 1 0.010
purine nucleoside monophosphate catabolic process GO:0009128 4 0.010
skeletal system development GO:0001501 181 0.010
action potential GO:0001508 19 0.010
regulation of nucleotide biosynthetic process GO:0030808 15 0.010
fin development GO:0033333 77 0.010

polr3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.030
sensory system disease DOID:0050155 0 0.015