Danio rerio

24 known processes

pomca

proopiomelanocortin a

(Aliases: SI:bZ36D5.4,SI:bZ36D5.1,si:bz36d5.2,MSH,ACTH,pomc)

pomca biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
pigment granule localization GO:0051875 25 0.935
pigment granule aggregation in cell center GO:0051877 8 0.910
establishment of pigment granule localization GO:0051905 22 0.906
endocrine process GO:0050886 2 0.835
Mouse
response to chemical GO:0042221 320 0.808
forebrain development GO:0030900 96 0.759
regulation of lipid catabolic process GO:0050994 2 0.728
positive regulation of lipid catabolic process GO:0050996 1 0.728
digestive system development GO:0055123 289 0.728
single organism transport GO:0044765 206 0.681
Mouse
tube morphogenesis GO:0035239 349 0.652
establishment of vesicle localization GO:0051650 24 0.608
endocrine system development GO:0035270 65 0.565
axonogenesis GO:0007409 152 0.547
cell growth GO:0016049 57 0.460
embryonic organ development GO:0048568 381 0.432
vesicle localization GO:0051648 27 0.417
specification of symmetry GO:0009799 204 0.414
cellular nitrogen compound biosynthetic process GO:0044271 218 0.409
response to food GO:0032094 1 0.408
enzyme linked receptor protein signaling pathway GO:0007167 106 0.396
regulation of anatomical structure morphogenesis GO:0022603 130 0.389
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.384
determination of left right symmetry GO:0007368 179 0.380
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.373
cellular response to chemical stimulus GO:0070887 157 0.358
lipid catabolic process GO:0016042 4 0.356
negative regulation of signaling GO:0023057 96 0.348
developmental growth involved in morphogenesis GO:0060560 86 0.344
circadian sleep wake cycle GO:0042745 2 0.333
regulation of hormone levels GO:0010817 21 0.328
Mouse
regulation of multicellular organism growth GO:0040014 4 0.323
morphogenesis of an epithelium GO:0002009 333 0.318
regulation of signal transduction GO:0009966 225 0.313
negative regulation of phosphate metabolic process GO:0045936 13 0.303
cell surface receptor signaling pathway GO:0007166 325 0.293
digestive tract morphogenesis GO:0048546 231 0.293
transcription from rna polymerase ii promoter GO:0006366 80 0.291
cartilage development GO:0051216 96 0.283
blood vessel development GO:0001568 246 0.282
regulation of primary metabolic process GO:0080090 311 0.279
Mouse
otic vesicle development GO:0071599 42 0.272
regulation of cell communication GO:0010646 232 0.269
Mouse
connective tissue development GO:0061448 99 0.260
positive regulation of lipid metabolic process GO:0045834 1 0.259
insulin like growth factor receptor signaling pathway GO:0048009 4 0.257
response to hormone GO:0009725 48 0.256
cellular response to organic cyclic compound GO:0071407 38 0.251
determination of bilateral symmetry GO:0009855 204 0.249
sensory perception of smell GO:0007608 2 0.246
striated muscle tissue development GO:0014706 110 0.244
response to organic substance GO:0010033 153 0.243
pigmentation GO:0043473 85 0.238
gastrulation GO:0007369 208 0.236
response to nutrient GO:0007584 3 0.229
sensory organ development GO:0007423 393 0.223
response to endogenous stimulus GO:0009719 83 0.218
cell projection organization GO:0030030 284 0.217
hormone biosynthetic process GO:0042446 3 0.214
response to oxygen levels GO:0070482 25 0.214
segmentation GO:0035282 97 0.214
female gonad development GO:0008585 4 0.213
negative regulation of feeding behavior GO:2000252 2 0.212
heart development GO:0007507 313 0.208
adipose tissue development GO:0060612 1 0.202
regulation of circadian sleep wake cycle GO:0042749 1 0.200
circadian sleep wake cycle process GO:0022410 2 0.199
positive regulation of catabolic process GO:0009896 4 0.198
diencephalon development GO:0021536 58 0.197
establishment of organelle localization GO:0051656 45 0.194
sequestering of calcium ion GO:0051208 3 0.191
blood circulation GO:0008015 87 0.191
Mouse
axon development GO:0061564 166 0.191
embryonic camera type eye morphogenesis GO:0048596 19 0.188
regionalization GO:0003002 274 0.185
developmental growth GO:0048589 166 0.184
determination of heart left right asymmetry GO:0061371 117 0.182
otic placode formation GO:0043049 23 0.182
digestive tract development GO:0048565 265 0.172
sequestering of metal ion GO:0051238 3 0.171
regulation of multicellular organismal process GO:0051239 277 0.171
Mouse
positive regulation of reproductive process GO:2000243 2 0.169
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.164
cell part morphogenesis GO:0032990 246 0.163
heart contraction GO:0060047 71 0.162
mitotic cell cycle GO:0000278 64 0.162
cellular macromolecule metabolic process GO:0044260 391 0.158
Mouse
regulation of cell death GO:0010941 103 0.156
negative regulation of cell communication GO:0010648 96 0.155
embryonic organ morphogenesis GO:0048562 274 0.154
generation of neurons GO:0048699 385 0.152
sensory organ morphogenesis GO:0090596 200 0.151
nuclear transport GO:0051169 4 0.149
negative regulation of biological process GO:0048519 304 0.148
g protein coupled receptor signaling pathway GO:0007186 74 0.146
regulation of rna metabolic process GO:0051252 224 0.146
regulation of signaling GO:0023051 235 0.145
Mouse
multicellular organism growth GO:0035264 4 0.143
organic cyclic compound biosynthetic process GO:1901362 223 0.141
regulation of cellular biosynthetic process GO:0031326 245 0.139
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.137
cell morphogenesis GO:0000902 289 0.136
hormone metabolic process GO:0042445 19 0.130
neuron projection guidance GO:0097485 86 0.129
embryonic eye morphogenesis GO:0048048 30 0.127
skeletal system development GO:0001501 181 0.125
morphogenesis of an epithelial sheet GO:0002011 49 0.123
developmental cell growth GO:0048588 52 0.119
biosynthetic process GO:0009058 294 0.118
regulation of metabolic process GO:0019222 359 0.118
Mouse
cell projection morphogenesis GO:0048858 244 0.118
organic cyclic compound metabolic process GO:1901360 301 0.118
neuron development GO:0048666 262 0.116
apoptotic process GO:0006915 116 0.114
neuron projection morphogenesis GO:0048812 161 0.113
cellular pigmentation GO:0033059 30 0.112
response to lipid GO:0033993 60 0.111
circadian sleep wake cycle sleep GO:0050802 1 0.111
sensory system development GO:0048880 76 0.110
aromatic compound biosynthetic process GO:0019438 217 0.110
protein targeting to nucleus GO:0044744 3 0.109
vasculature development GO:0001944 278 0.106
regulation of heart morphogenesis GO:2000826 17 0.106
aging GO:0007568 2 0.106
positive regulation of cell cycle GO:0045787 3 0.105
single organism organelle organization GO:1902589 199 0.104
actin filament based process GO:0030029 64 0.103
regulation of multicellular organismal development GO:2000026 223 0.103
dorsal ventral pattern formation GO:0009953 125 0.101
cell death GO:0008219 121 0.100
cellular macromolecule biosynthetic process GO:0034645 224 0.099
protein import GO:0017038 3 0.098
negative regulation of signal transduction GO:0009968 94 0.097
epithelial tube morphogenesis GO:0060562 148 0.096
mesoderm development GO:0007498 88 0.096
axon extension GO:0048675 45 0.095
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.095
Mouse
primary amino compound biosynthetic process GO:1901162 1 0.095
inner ear morphogenesis GO:0042472 63 0.095
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.094
positive regulation of jak stat cascade GO:0046427 2 0.094
central nervous system development GO:0007417 387 0.090
gabaergic neuron differentiation GO:0097154 2 0.090
heart morphogenesis GO:0003007 156 0.089
neuron projection extension GO:1990138 45 0.089
foregut morphogenesis GO:0007440 4 0.089
epiboly GO:0090504 41 0.088
cellular response to organic substance GO:0071310 105 0.088
response to organic cyclic compound GO:0014070 51 0.088
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.087
cytokinesis GO:0000910 3 0.086
response to decreased oxygen levels GO:0036293 25 0.085
negative regulation of protein kinase activity GO:0006469 4 0.085
regulation of developmental growth GO:0048638 38 0.083
organic substance biosynthetic process GO:1901576 289 0.082
protein import into nucleus GO:0006606 3 0.081
female sex differentiation GO:0046660 4 0.081
regulation of behavior GO:0050795 24 0.081
regulation of cellular amine metabolic process GO:0033238 0 0.081
response to abiotic stimulus GO:0009628 122 0.079
regulation of establishment of protein localization GO:0070201 4 0.079
protein localization GO:0008104 40 0.079
response to growth factor GO:0070848 39 0.078
regulation of organ morphogenesis GO:2000027 35 0.077
cellular biosynthetic process GO:0044249 286 0.077
regulation of cellular metabolic process GO:0031323 320 0.076
Mouse
muscle system process GO:0003012 20 0.076
regulation of growth GO:0040008 42 0.075
cell morphogenesis involved in differentiation GO:0000904 195 0.075
regulation of cellular amino acid metabolic process GO:0006521 0 0.074
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.074
signal transduction GO:0007165 455 0.072
positive regulation of metabolic process GO:0009893 108 0.072
establishment of localization GO:0051234 244 0.071
Mouse
serotonin metabolic process GO:0042428 1 0.071
wnt signaling pathway GO:0016055 80 0.070
heart looping GO:0001947 94 0.069
negative regulation of kinase activity GO:0033673 4 0.068
circulatory system process GO:0003013 87 0.067
Mouse
post embryonic morphogenesis GO:0009886 4 0.067
negative regulation of response to stimulus GO:0048585 104 0.067
negative regulation of map kinase activity GO:0043407 2 0.066
gland development GO:0048732 143 0.066
behavior GO:0007610 74 0.066
positive regulation of cellular metabolic process GO:0031325 94 0.065
ovulation cycle process GO:0022602 2 0.065
positive regulation of rna metabolic process GO:0051254 59 0.065
single organism nuclear import GO:1902593 3 0.064
response to radiation GO:0009314 51 0.064
response to transition metal nanoparticle GO:1990267 28 0.063
regulation of apoptotic process GO:0042981 98 0.063
regulation of nitrogen compound metabolic process GO:0051171 251 0.063
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.062
glucocorticoid metabolic process GO:0008211 2 0.061
ion transmembrane transport GO:0034220 91 0.061
negative regulation of programmed cell death GO:0043069 58 0.060
negative regulation of cell death GO:0060548 60 0.059
response to external stimulus GO:0009605 264 0.058
cellular modified amino acid metabolic process GO:0006575 3 0.058
negative regulation of apoptotic process GO:0043066 55 0.058
neuron fate specification GO:0048665 20 0.058
sleep GO:0030431 1 0.058
mesenchyme development GO:0060485 127 0.058
neuron fate commitment GO:0048663 26 0.057
positive regulation of rna biosynthetic process GO:1902680 57 0.057
notochord development GO:0030903 54 0.057
inositol phosphate metabolic process GO:0043647 1 0.057
inner ear development GO:0048839 126 0.056
negative regulation of cellular process GO:0048523 283 0.056
neuron projection development GO:0031175 180 0.056
positive regulation of nucleic acid templated transcription GO:1903508 57 0.056
negative regulation of molecular function GO:0044092 23 0.056
ectoderm development GO:0007398 9 0.056
embryonic heart tube morphogenesis GO:0003143 108 0.055
response to hypoxia GO:0001666 25 0.055
regulation of cellular component organization GO:0051128 86 0.054
protein localization to nucleus GO:0034504 3 0.054
regulation of intracellular signal transduction GO:1902531 57 0.053
dicarboxylic acid transport GO:0006835 1 0.053
localization of cell GO:0051674 244 0.052
regulation of biological quality GO:0065008 263 0.052
Mouse
positive regulation of cellular process GO:0048522 201 0.052
catecholamine metabolic process GO:0006584 2 0.051
positive regulation of transport GO:0051050 2 0.051
brain development GO:0007420 293 0.051
positive regulation of signal transduction GO:0009967 56 0.051
regulation of programmed cell death GO:0043067 101 0.050
ovulation cycle GO:0042698 2 0.050
cell proliferation GO:0008283 80 0.050
ear morphogenesis GO:0042471 64 0.050
regulation of locomotion GO:0040012 55 0.050
establishment of protein localization to organelle GO:0072594 4 0.050
system process GO:0003008 185 0.050
Mouse
regulation of synaptic plasticity GO:0048167 1 0.050
negative regulation of metabolic process GO:0009892 86 0.049
death GO:0016265 121 0.049
positive regulation of gene expression GO:0010628 71 0.049
positive regulation of cellular biosynthetic process GO:0031328 68 0.048
hard palate development GO:0060022 4 0.048
organonitrogen compound metabolic process GO:1901564 74 0.048
angiogenesis GO:0001525 158 0.048
positive regulation of cell communication GO:0010647 56 0.047
rna biosynthetic process GO:0032774 181 0.047
hindbrain development GO:0030902 91 0.047
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.046
nucleocytoplasmic transport GO:0006913 4 0.046
gastrulation with mouth forming second GO:0001702 44 0.045
spinal cord motor neuron cell fate specification GO:0021520 8 0.044
response to oxygen containing compound GO:1901700 55 0.043
positive regulation of response to stimulus GO:0048584 80 0.043
calcium ion transport into cytosol GO:0060402 3 0.043
regulation of reproductive process GO:2000241 4 0.042
regulation of cell size GO:0008361 29 0.042
growth GO:0040007 174 0.042
response to vitamin GO:0033273 3 0.041
amino acid transport GO:0006865 2 0.041
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.041
positive regulation of biological process GO:0048518 253 0.040
programmed cell death GO:0012501 119 0.040
regulation of cellular ketone metabolic process GO:0010565 7 0.040
cellular amine metabolic process GO:0044106 2 0.040
nuclear import GO:0051170 3 0.040
cyclic purine nucleotide metabolic process GO:0052652 18 0.040
positive regulation of cell division GO:0051781 2 0.039
organic substance transport GO:0071702 58 0.039
Mouse
steroid metabolic process GO:0008202 7 0.039
multi organism process GO:0051704 134 0.039
peptide transport GO:0015833 1 0.038
regulation of biosynthetic process GO:0009889 250 0.038
macromolecule biosynthetic process GO:0009059 227 0.038
positive regulation of cell death GO:0010942 29 0.038
single organism localization GO:1902578 225 0.038
Mouse
lateral line development GO:0048882 66 0.037
stem cell proliferation GO:0072089 4 0.037
heterocycle metabolic process GO:0046483 290 0.037
response to nutrient levels GO:0031667 10 0.037
multi organism reproductive process GO:0044703 36 0.036
ventral spinal cord development GO:0021517 35 0.036
gland morphogenesis GO:0022612 13 0.036
protein polymerization GO:0051258 4 0.036
development of primary female sexual characteristics GO:0046545 4 0.036
chemical homeostasis GO:0048878 49 0.035
Mouse
negative regulation of behavior GO:0048521 6 0.035
response to steroid hormone GO:0048545 35 0.035
muscle organ development GO:0007517 101 0.035
regulation of protein complex assembly GO:0043254 3 0.034
cellular response to steroid hormone stimulus GO:0071383 31 0.034
organelle localization GO:0051640 49 0.034
cellular amino acid metabolic process GO:0006520 7 0.034
carboxylic acid metabolic process GO:0019752 22 0.034
regulation of anatomical structure size GO:0090066 33 0.033
positive regulation of camp metabolic process GO:0030816 2 0.033
regulation of nucleic acid templated transcription GO:1903506 213 0.033
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.033
regulation of systemic arterial blood pressure GO:0003073 1 0.033
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.033
response to drug GO:0042493 3 0.033
positive regulation of biosynthetic process GO:0009891 68 0.033
regulation of macromolecule biosynthetic process GO:0010556 225 0.033
adenohypophysis development GO:0021984 15 0.032
single organism metabolic process GO:0044710 217 0.032
Mouse
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.032
intracellular signal transduction GO:0035556 85 0.032
regulation of hormone secretion GO:0046883 2 0.032
Mouse
catechol containing compound metabolic process GO:0009712 2 0.032
regulation of protein transport GO:0051223 3 0.032
purine nucleotide biosynthetic process GO:0006164 20 0.031
gene expression GO:0010467 252 0.031
ear development GO:0043583 127 0.031
cellular hormone metabolic process GO:0034754 19 0.031
phasic smooth muscle contraction GO:0014821 1 0.031
positive regulation of map kinase activity GO:0043406 3 0.031
heterocycle biosynthetic process GO:0018130 215 0.031
embryonic heart tube development GO:0035050 133 0.031
transport GO:0006810 220 0.031
Mouse
reproductive process GO:0022414 40 0.031
positive regulation of apoptotic signaling pathway GO:2001235 1 0.030
muscle contraction GO:0006936 18 0.030
response to other organism GO:0051707 97 0.030
response to alkaloid GO:0043279 2 0.030
primary amino compound metabolic process GO:1901160 1 0.029
cell differentiation in spinal cord GO:0021515 40 0.029
cellular carbohydrate metabolic process GO:0044262 4 0.029
Mouse
cellular response to endogenous stimulus GO:0071495 68 0.029
axon guidance GO:0007411 86 0.029
regulation of cell development GO:0060284 100 0.029
regulation of localization GO:0032879 104 0.029
Mouse
ovarian follicle development GO:0001541 2 0.029
stem cell division GO:0017145 1 0.029
negative regulation of protein kinase b signaling GO:0051898 2 0.029
limbic system development GO:0021761 16 0.028
negative regulation of camp biosynthetic process GO:0030818 7 0.028
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.028
mesoderm morphogenesis GO:0048332 51 0.028
neuron differentiation GO:0030182 353 0.028
negative regulation of protein phosphorylation GO:0001933 4 0.027
regulation of developmental process GO:0050793 247 0.027
hormone transport GO:0009914 2 0.027
Mouse
ameboidal type cell migration GO:0001667 143 0.027
cellular localization GO:0051641 97 0.027
nucleic acid metabolic process GO:0090304 244 0.027
ectodermal placode morphogenesis GO:0071697 32 0.027
xenobiotic metabolic process GO:0006805 4 0.026
positive regulation of cellular amine metabolic process GO:0033240 0 0.026
cell migration GO:0016477 237 0.025
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.025
muscle structure development GO:0061061 196 0.025
growth plate cartilage morphogenesis GO:0003422 1 0.025
cellular protein complex assembly GO:0043623 19 0.025
response to xenobiotic stimulus GO:0009410 45 0.025
adult behavior GO:0030534 2 0.025
regulation of cell migration GO:0030334 40 0.025
oxoacid metabolic process GO:0043436 31 0.025
cellular component morphogenesis GO:0032989 336 0.025
cytoskeleton organization GO:0007010 96 0.025
regulation of carbohydrate biosynthetic process GO:0043255 1 0.025
regulation of cellular component movement GO:0051270 55 0.025
response to glucocorticoid GO:0051384 1 0.024
response to stress GO:0006950 263 0.024
regulation of response to stimulus GO:0048583 269 0.024
negative regulation of nucleotide biosynthetic process GO:0030809 7 0.024
response to nicotine GO:0035094 2 0.023
tissue regeneration GO:0042246 74 0.023
ion transport GO:0006811 114 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.023
posterior lateral line neuromast primordium migration GO:0048920 12 0.023
axis elongation GO:0003401 31 0.023
response to methanol GO:0033986 4 0.022
regulation of inflammatory response GO:0050727 2 0.022
lipid metabolic process GO:0006629 52 0.022
response to ketone GO:1901654 1 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.022
monovalent inorganic cation homeostasis GO:0055067 9 0.022
hypothalamus development GO:0021854 14 0.022
cell migration involved in gastrulation GO:0042074 79 0.022
organophosphate biosynthetic process GO:0090407 23 0.022
chemotaxis GO:0006935 104 0.022
eye morphogenesis GO:0048592 144 0.022
entrainment of circadian clock GO:0009649 2 0.022
small molecule metabolic process GO:0044281 77 0.022
otic vesicle morphogenesis GO:0071600 34 0.022
neural tube development GO:0021915 62 0.022
oligodendrocyte cell fate specification GO:0021778 4 0.022
negative regulation of cellular metabolic process GO:0031324 77 0.022
regulation of neurogenesis GO:0050767 87 0.022
hormone mediated signaling pathway GO:0009755 9 0.022
hormone secretion GO:0046879 2 0.022
Mouse
wound healing GO:0042060 90 0.022
cell division GO:0051301 20 0.022
regulation of cyclic nucleotide biosynthetic process GO:0030802 15 0.022
regulation of sodium ion transport GO:0002028 2 0.021
regulation of cellular response to growth factor stimulus GO:0090287 35 0.021
intracellular receptor signaling pathway GO:0030522 30 0.021
intracellular transport GO:0046907 32 0.021
regulation of sequestering of calcium ion GO:0051282 4 0.021
mitotic cell cycle process GO:1903047 48 0.021
regulation of extent of cell growth GO:0061387 29 0.021
regulation of carbohydrate metabolic process GO:0006109 4 0.021
Mouse
cellular protein metabolic process GO:0044267 129 0.021
response to mechanical stimulus GO:0009612 24 0.021
endoderm development GO:0007492 49 0.020
regulation of dna methylation GO:0044030 5 0.020
regulation of epithelial to mesenchymal transition GO:0010717 3 0.020
rna metabolic process GO:0016070 219 0.020
positive regulation of transcription dna templated GO:0045893 57 0.020
regulation of receptor mediated endocytosis GO:0048259 4 0.020
rhythmic behavior GO:0007622 5 0.020
regulation of protein import into nucleus GO:0042306 2 0.020
sprouting angiogenesis GO:0002040 53 0.020
negative regulation of macromolecule metabolic process GO:0010605 76 0.019
phenol containing compound metabolic process GO:0018958 5 0.019
regulation of cell growth GO:0001558 29 0.019
fin regeneration GO:0031101 51 0.019
amine metabolic process GO:0009308 2 0.019
chordate embryonic development GO:0043009 271 0.019
phagocytosis GO:0006909 3 0.019
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.019
response to wounding GO:0009611 116 0.019
protein heterooligomerization GO:0051291 1 0.019
cellular response to hormone stimulus GO:0032870 39 0.019
negative regulation of cellular biosynthetic process GO:0031327 55 0.019
hepatocyte proliferation GO:0072574 2 0.019
positive regulation of neural precursor cell proliferation GO:2000179 1 0.019
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.018
regulation of binding GO:0051098 3 0.018
optic placode formation involved in camera type eye formation GO:0046619 3 0.018
nephron morphogenesis GO:0072028 2 0.018
positive regulation of secretion GO:0051047 1 0.018
receptor internalization GO:0031623 2 0.018
negative regulation of wnt signaling pathway GO:0030178 30 0.018
skeletal muscle organ development GO:0060538 78 0.018
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.018
response to monosaccharide GO:0034284 3 0.018
photoperiodism GO:0009648 11 0.018
muscle tissue development GO:0060537 110 0.018
transmembrane transport GO:0055085 120 0.018
release of sequestered calcium ion into cytosol GO:0051209 3 0.018
positive regulation of embryonic development GO:0040019 3 0.018
camera type eye morphogenesis GO:0048593 108 0.017
cellular component assembly involved in morphogenesis GO:0010927 107 0.017
reflex GO:0060004 2 0.017
nitrogen compound metabolic process GO:0006807 319 0.017
negative regulation of hormone secretion GO:0046888 2 0.017
positive regulation of macromolecule metabolic process GO:0010604 93 0.017
morphogenesis of a branching structure GO:0001763 21 0.017
regulation of cellular ph GO:0030641 1 0.017
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.017
swim bladder development GO:0048794 19 0.017
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 1 0.017
regulation of metal ion transport GO:0010959 4 0.017
inositol phosphate biosynthetic process GO:0032958 1 0.017
divalent inorganic cation homeostasis GO:0072507 22 0.017
positive regulation of signaling GO:0023056 56 0.017
dopamine metabolic process GO:0042417 2 0.016
calcium ion dependent exocytosis GO:0017156 1 0.016
ion homeostasis GO:0050801 41 0.016
endocrine pancreas development GO:0031018 27 0.016
brain segmentation GO:0035284 6 0.016
embryonic camera type eye development GO:0031076 29 0.016
negative regulation of nucleotide metabolic process GO:0045980 7 0.016
leukocyte activation GO:0045321 12 0.016
organic acid metabolic process GO:0006082 31 0.016
sensory perception of chemical stimulus GO:0007606 3 0.016
positive regulation of programmed cell death GO:0043068 29 0.016
cellular component assembly GO:0022607 170 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.016
multicellular organismal reproductive process GO:0048609 35 0.016
calcium ion homeostasis GO:0055074 19 0.015
embryonic pattern specification GO:0009880 44 0.015
single organism cellular localization GO:1902580 46 0.015
ribonucleotide biosynthetic process GO:0009260 20 0.015
regulation of cellular component size GO:0032535 30 0.015
response to inorganic substance GO:0010035 38 0.015
positive regulation of secretion by cell GO:1903532 1 0.015
microtubule based process GO:0007017 60 0.015
otolith morphogenesis GO:0032474 8 0.015
regulation of axon extension GO:0030516 24 0.015
embryonic viscerocranium morphogenesis GO:0048703 52 0.015
cyclic nucleotide biosynthetic process GO:0009190 18 0.015
microtubule polymerization or depolymerization GO:0031109 3 0.015
inositol lipid mediated signaling GO:0048017 2 0.015
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.014
eye development GO:0001654 277 0.014
negative regulation of intracellular signal transduction GO:1902532 22 0.014
single organism reproductive process GO:0044702 40 0.014
regulation of epithelial cell proliferation GO:0050678 3 0.014
immune system process GO:0002376 241 0.014
negative regulation of catalytic activity GO:0043086 21 0.014
energy reserve metabolic process GO:0006112 2 0.014
Mouse
purine containing compound biosynthetic process GO:0072522 20 0.014
regulation of wnt signaling pathway involved in dorsal ventral axis specification GO:2000053 5 0.014
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.014
protein metabolic process GO:0019538 183 0.014
negative regulation of lyase activity GO:0051350 6 0.014
convergent extension GO:0060026 118 0.014
regulation of kinase activity GO:0043549 15 0.014

pomca disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.093
endocrine system disease DOID:28 0 0.084
disease of metabolism DOID:0014667 0 0.018