Danio rerio

0 known processes

pou2f1a

POU class 2 homeobox 1a

(Aliases: Oct-1,pouII1,oct1)

pou2f1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule metabolic process GO:0044260 391 0.508
Zebrafish Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.424
Zebrafish Fly
regulation of rna metabolic process GO:0051252 224 0.351
Zebrafish Fly
nucleobase containing compound metabolic process GO:0006139 274 0.345
Zebrafish Fly
regulation of cellular metabolic process GO:0031323 320 0.313
Zebrafish Fly
larval development GO:0002164 2 0.304
aromatic compound biosynthetic process GO:0019438 217 0.286
Zebrafish Fly
biosynthetic process GO:0009058 294 0.279
Zebrafish Fly
central nervous system development GO:0007417 387 0.264
Zebrafish Fly
heterocycle metabolic process GO:0046483 290 0.263
Zebrafish Fly
brain development GO:0007420 293 0.259
Zebrafish
regulation of metabolic process GO:0019222 359 0.254
Zebrafish Fly
regulation of gene expression GO:0010468 265 0.250
Zebrafish Fly
cellular biosynthetic process GO:0044249 286 0.240
Zebrafish Fly
determination of bilateral symmetry GO:0009855 204 0.218
regulation of macromolecule metabolic process GO:0060255 317 0.217
Zebrafish Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.215
Zebrafish Fly
gene expression GO:0010467 252 0.209
Zebrafish Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.204
Zebrafish Fly
macromolecule biosynthetic process GO:0009059 227 0.198
Zebrafish Fly
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.197
Zebrafish Fly
dorsal ventral pattern formation GO:0009953 125 0.192
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.185
Zebrafish Fly
nucleic acid metabolic process GO:0090304 244 0.164
Zebrafish Fly
nucleic acid templated transcription GO:0097659 181 0.164
Zebrafish Fly
organic substance biosynthetic process GO:1901576 289 0.161
Zebrafish Fly
aging GO:0007568 2 0.160
Worm
regulation of endodermal cell fate specification GO:0042663 15 0.157
Zebrafish
cellular aromatic compound metabolic process GO:0006725 295 0.146
Zebrafish Fly
formation of primary germ layer GO:0001704 62 0.145
Zebrafish
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.145
cellular protein catabolic process GO:0044257 4 0.143
heterocycle biosynthetic process GO:0018130 215 0.141
Zebrafish Fly
rna metabolic process GO:0016070 219 0.135
Zebrafish Fly
cell fate commitment GO:0045165 99 0.132
Zebrafish
response to abiotic stimulus GO:0009628 122 0.124
muscle cell differentiation GO:0042692 139 0.122
cellular macromolecule biosynthetic process GO:0034645 224 0.122
Zebrafish Fly
modification dependent macromolecule catabolic process GO:0043632 3 0.118
regulation of primary metabolic process GO:0080090 311 0.114
Zebrafish Fly
positive regulation of biological process GO:0048518 253 0.109
Zebrafish Fly
regulation of cellular biosynthetic process GO:0031326 245 0.105
Zebrafish Fly
sleep GO:0030431 1 0.104
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.101
Zebrafish Fly
single organism localization GO:1902578 225 0.097
nitrogen compound metabolic process GO:0006807 319 0.096
Zebrafish Fly
system process GO:0003008 185 0.093
embryonic organ morphogenesis GO:0048562 274 0.089
mitotic cell cycle GO:0000278 64 0.088
head development GO:0060322 303 0.087
Zebrafish
mesoderm formation GO:0001707 43 0.084
ubiquitin dependent protein catabolic process GO:0006511 3 0.081
regulation of mrna processing GO:0050684 3 0.081
positive regulation of jun kinase activity GO:0043507 2 0.078
maintenance of location GO:0051235 4 0.077
cellular nitrogen compound metabolic process GO:0034641 290 0.074
Zebrafish Fly
neuroblast proliferation GO:0007405 2 0.073
positive regulation of cellular biosynthetic process GO:0031328 68 0.066
Zebrafish Fly
positive regulation of cell cycle GO:0045787 3 0.065
heart looping GO:0001947 94 0.064
embryonic organ development GO:0048568 381 0.062
ear development GO:0043583 127 0.060
regulation of protein catabolic process GO:0042176 1 0.059
modification dependent protein catabolic process GO:0019941 3 0.059
digestive tract development GO:0048565 265 0.057
Zebrafish
circadian sleep wake cycle sleep GO:0050802 1 0.057
cardiac cell fate commitment GO:0060911 1 0.057
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.057
tube morphogenesis GO:0035239 349 0.056
Zebrafish
endodermal cell differentiation GO:0035987 19 0.055
Zebrafish
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.054
Zebrafish
negative regulation of biological process GO:0048519 304 0.054
Worm
regulation of dna replication GO:0006275 3 0.053
negative regulation of biosynthetic process GO:0009890 55 0.052
negative regulation of metabolic process GO:0009892 86 0.051
regulation of signal transduction GO:0009966 225 0.049
skeletal muscle tissue development GO:0007519 67 0.048
negative regulation of tor signaling GO:0032007 2 0.047
regulation of circadian sleep wake cycle GO:0042749 1 0.047
gastrulation GO:0007369 208 0.047
Zebrafish
macromolecule catabolic process GO:0009057 15 0.047
negative regulation of cellular metabolic process GO:0031324 77 0.047
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.047
regulation of cell fate specification GO:0042659 20 0.046
Zebrafish
specification of symmetry GO:0009799 204 0.046
chemotaxis GO:0006935 104 0.046
embryo development ending in birth or egg hatching GO:0009792 271 0.045
Worm
blood vessel morphogenesis GO:0048514 216 0.045
regulation of jun kinase activity GO:0043506 3 0.045
axonogenesis GO:0007409 152 0.044
muscle structure development GO:0061061 196 0.044
endoderm development GO:0007492 49 0.043
Zebrafish
proteasomal protein catabolic process GO:0010498 2 0.043
regulation of macromolecule biosynthetic process GO:0010556 225 0.042
Zebrafish Fly
muscle tissue development GO:0060537 110 0.042
endodermal cell fate specification GO:0001714 17 0.042
Zebrafish
axon guidance GO:0007411 86 0.041
regulation of biosynthetic process GO:0009889 250 0.040
Zebrafish Fly
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.040
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.039
lymphatic endothelial cell fate commitment GO:0060838 1 0.039
mesenchyme development GO:0060485 127 0.039
cellular response to chemical stimulus GO:0070887 157 0.039
regulation of rna biosynthetic process GO:2001141 213 0.038
Zebrafish Fly
cardiac atrium development GO:0003230 4 0.037
mesoderm development GO:0007498 88 0.037
Zebrafish
vasculature development GO:0001944 278 0.037
negative regulation of rna metabolic process GO:0051253 48 0.037
positive regulation of catabolic process GO:0009896 4 0.036
negative regulation of macromolecule metabolic process GO:0010605 76 0.036
rna biosynthetic process GO:0032774 181 0.036
Zebrafish Fly
mitotic cell cycle process GO:1903047 48 0.036
digestive system development GO:0055123 289 0.036
Zebrafish
neuron differentiation GO:0030182 353 0.035
regionalization GO:0003002 274 0.035
Zebrafish
mesoderm morphogenesis GO:0048332 51 0.035
blood vessel development GO:0001568 246 0.035
septum transversum development GO:0003343 4 0.034
digestive tract morphogenesis GO:0048546 231 0.034
Zebrafish
taxis GO:0042330 109 0.034
regulation of multicellular organismal process GO:0051239 277 0.033
Zebrafish Worm
skeletal muscle organ development GO:0060538 78 0.033
heart development GO:0007507 313 0.033
generation of neurons GO:0048699 385 0.032
Fly
regulation of circadian rhythm GO:0042752 4 0.032
regulation of response to stimulus GO:0048583 269 0.031
negative regulation of gene expression GO:0010629 65 0.031
embryonic hemopoiesis GO:0035162 53 0.031
locomotion GO:0040011 313 0.031
Worm
transcription dna templated GO:0006351 181 0.030
Zebrafish Fly
regulation of cell growth GO:0001558 29 0.030
positive regulation of cellular catabolic process GO:0031331 3 0.030
stem cell proliferation GO:0072089 4 0.030
cardiocyte differentiation GO:0035051 44 0.030
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.030
Zebrafish Fly
nuclear transport GO:0051169 4 0.030
regulation of neurogenesis GO:0050767 87 0.029
endoderm formation GO:0001706 29 0.029
Zebrafish
negative regulation of cellular process GO:0048523 283 0.029
Worm
protein metabolic process GO:0019538 183 0.029
stem cell division GO:0017145 1 0.029
cell growth GO:0016049 57 0.029
gastrulation with mouth forming second GO:0001702 44 0.028
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.028
Zebrafish Fly
forebrain development GO:0030900 96 0.028
transcription from rna polymerase ii promoter GO:0006366 80 0.028
Fly
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.028
Zebrafish Fly
positive regulation of jnk cascade GO:0046330 3 0.028
response to external stimulus GO:0009605 264 0.027
axon development GO:0061564 166 0.027
positive regulation of dna metabolic process GO:0051054 1 0.027
regulation of mesoderm development GO:2000380 11 0.027
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.027
Zebrafish Fly
response to chemical GO:0042221 320 0.027
cell cell signaling GO:0007267 52 0.026
regulation of embryonic development GO:0045995 47 0.026
Zebrafish
regulation of gastrulation GO:0010470 24 0.026
Zebrafish
regulation of cell fate commitment GO:0010453 22 0.025
Zebrafish
lateral inhibition GO:0046331 1 0.025
regulation of stem cell differentiation GO:2000736 4 0.025
embryonic heart tube development GO:0035050 133 0.025
chordate embryonic development GO:0043009 271 0.024
circadian sleep wake cycle process GO:0022410 2 0.024
meiotic cell cycle process GO:1903046 3 0.024
spindle assembly GO:0051225 2 0.024
striated muscle tissue development GO:0014706 110 0.024
negative regulation of rna biosynthetic process GO:1902679 45 0.024
regulation of cytoplasmic transport GO:1903649 4 0.023
growth GO:0040007 174 0.023
Zebrafish
neuron projection guidance GO:0097485 86 0.023
circadian sleep wake cycle GO:0042745 2 0.023
stem cell development GO:0048864 82 0.023
Fly
determination of left right symmetry GO:0007368 179 0.023
regulation of oocyte development GO:0060281 3 0.023
Worm
negative regulation of catabolic process GO:0009895 3 0.023
lipid storage GO:0019915 1 0.023
epidermis development GO:0008544 48 0.022
Worm
camera type eye development GO:0043010 222 0.022
embryonic heart tube morphogenesis GO:0003143 108 0.022
regulation of multicellular organism growth GO:0040014 4 0.022
response to stress GO:0006950 263 0.022
Zebrafish
organelle fission GO:0048285 23 0.022
negative regulation of cellular biosynthetic process GO:0031327 55 0.022
striated muscle cell differentiation GO:0051146 129 0.022
negative regulation of developmental process GO:0051093 65 0.022
Worm
sensory organ morphogenesis GO:0090596 200 0.022
determination of heart left right asymmetry GO:0061371 117 0.022
determination of dorsal ventral asymmetry GO:0048262 34 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.021
positive regulation of biosynthetic process GO:0009891 68 0.021
Zebrafish Fly
negative regulation of programmed cell death GO:0043069 58 0.021
cellular component movement GO:0006928 335 0.021
Worm
single organism organelle organization GO:1902589 199 0.020
negative regulation of cell death GO:0060548 60 0.020
neurological system process GO:0050877 62 0.020
terpenoid metabolic process GO:0006721 15 0.020
organonitrogen compound metabolic process GO:1901564 74 0.020
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.020
eye development GO:0001654 277 0.020
hindbrain development GO:0030902 91 0.020
Zebrafish
cellular response to external stimulus GO:0071496 2 0.020
cell part morphogenesis GO:0032990 246 0.020
stem cell maintenance GO:0019827 4 0.020
positive regulation of cellular component biogenesis GO:0044089 3 0.019
neuron projection development GO:0031175 180 0.019
positive regulation of map kinase activity GO:0043406 3 0.019
cellular component morphogenesis GO:0032989 336 0.019
negative regulation of transcription dna templated GO:0045892 45 0.019
negative regulation of mitosis GO:0045839 3 0.019
cytoskeleton organization GO:0007010 96 0.019
regulation of cellular protein catabolic process GO:1903362 1 0.019
cell surface receptor signaling pathway GO:0007166 325 0.019
positive regulation of signaling GO:0023056 56 0.019
regulation of signaling GO:0023051 235 0.019
type b pancreatic cell development GO:0003323 4 0.019
regulation of anatomical structure morphogenesis GO:0022603 130 0.018
Zebrafish
endodermal cell fate determination GO:0007493 2 0.018
negative regulation of cell fate specification GO:0009996 11 0.018
cell substrate adhesion GO:0031589 4 0.018
negative regulation of chromosome organization GO:2001251 1 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.018
Fly
cellular ketone metabolic process GO:0042180 11 0.018
g2 m transition of mitotic cell cycle GO:0000086 4 0.018
regulation of transcription dna templated GO:0006355 213 0.018
Zebrafish Fly
organic acid metabolic process GO:0006082 31 0.018
single organism biosynthetic process GO:0044711 71 0.017
positive regulation of muscle organ development GO:0048636 1 0.017
signal transduction GO:0007165 455 0.017
regulation of nervous system development GO:0051960 90 0.017
positive regulation of rna biosynthetic process GO:1902680 57 0.017
Zebrafish Fly
response to light stimulus GO:0009416 46 0.017
regulation of axon extension GO:0030516 24 0.017
negative regulation of nucleic acid templated transcription GO:1903507 45 0.017
amine metabolic process GO:0009308 2 0.017
regulation of reproductive process GO:2000241 4 0.017
Worm
tetrapyrrole metabolic process GO:0033013 10 0.017
skeletal system development GO:0001501 181 0.017
response to xenobiotic stimulus GO:0009410 45 0.017
retina development in camera type eye GO:0060041 146 0.017
proepicardium development GO:0003342 4 0.017
ear morphogenesis GO:0042471 64 0.017
negative regulation of cellular catabolic process GO:0031330 3 0.016
meiotic nuclear division GO:0007126 4 0.016
phagocytosis GO:0006909 3 0.016
regulation of developmental process GO:0050793 247 0.016
Zebrafish Worm
positive regulation of cellular process GO:0048522 201 0.016
Zebrafish Fly
ameboidal type cell migration GO:0001667 143 0.016
organelle organization GO:0006996 227 0.016
response to temperature stimulus GO:0009266 15 0.016
regulation of dna metabolic process GO:0051052 11 0.016
Zebrafish
nucleobase containing compound biosynthetic process GO:0034654 205 0.016
Zebrafish Fly
multicellular organismal signaling GO:0035637 22 0.016
regulation of organ growth GO:0046620 3 0.016
muscle organ development GO:0007517 101 0.015
cellular protein metabolic process GO:0044267 129 0.015
establishment of spindle orientation GO:0051294 10 0.015
single organism metabolic process GO:0044710 217 0.015
phosphorylation GO:0016310 69 0.015
nucleocytoplasmic transport GO:0006913 4 0.015
diencephalon development GO:0021536 58 0.015
regulation of synapse organization GO:0050807 3 0.015
regulation of cellular component organization GO:0051128 86 0.015
establishment of apical basal cell polarity GO:0035089 2 0.015
actin cytoskeleton organization GO:0030036 63 0.015
oxoacid metabolic process GO:0043436 31 0.015
regulation of cytokine production GO:0001817 3 0.015
cell projection organization GO:0030030 284 0.015
embryonic limb morphogenesis GO:0030326 2 0.015
cardiac atrium morphogenesis GO:0003209 2 0.014
regulation of mesodermal cell fate specification GO:0042661 9 0.014
female sex differentiation GO:0046660 4 0.014
macromolecule modification GO:0043412 111 0.014
Zebrafish
retinal ganglion cell axon guidance GO:0031290 35 0.014
cell death GO:0008219 121 0.014
determination of ventral identity GO:0048264 21 0.014
lateral line system development GO:0048925 76 0.014
mesodermal cell fate commitment GO:0001710 14 0.014
multicellular organism reproduction GO:0032504 35 0.013
Worm
heart morphogenesis GO:0003007 156 0.013
angiogenesis GO:0001525 158 0.013
inner ear development GO:0048839 126 0.013
bmp signaling pathway GO:0030509 52 0.013
neuron development GO:0048666 262 0.013
spermatid development GO:0007286 2 0.013
neuronal action potential GO:0019228 18 0.013
positive regulation of notch signaling pathway GO:0045747 3 0.013
phosphorus metabolic process GO:0006793 109 0.013
positive regulation of developmental process GO:0051094 50 0.013
cellular macromolecule catabolic process GO:0044265 12 0.013
negative regulation of mesodermal cell fate specification GO:0042662 3 0.013
negative regulation of collateral sprouting GO:0048671 2 0.013
regulation of organ morphogenesis GO:2000027 35 0.013
epithelial tube morphogenesis GO:0060562 148 0.013
wnt signaling pathway GO:0016055 80 0.012
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.012
synaptic growth at neuromuscular junction GO:0051124 2 0.012
regulation of cellular ketone metabolic process GO:0010565 7 0.012
microtubule based process GO:0007017 60 0.012
sensory organ development GO:0007423 393 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
regulation of apoptotic process GO:0042981 98 0.012
negative regulation of cytokine production GO:0001818 1 0.012
mitotic nuclear division GO:0007067 18 0.012
endodermal cell fate commitment GO:0001711 18 0.012
Zebrafish
central nervous system neuron differentiation GO:0021953 74 0.012
somitogenesis GO:0001756 87 0.012
cell projection morphogenesis GO:0048858 244 0.012
cell morphogenesis GO:0000902 289 0.012
small molecule metabolic process GO:0044281 77 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.012
cardiac muscle cell differentiation GO:0055007 30 0.012
programmed cell death GO:0012501 119 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
Zebrafish
regulation of cell differentiation GO:0045595 142 0.012
Zebrafish Worm
regulation of anatomical structure size GO:0090066 33 0.012
positive regulation of molecular function GO:0044093 33 0.012
semicircular canal morphogenesis GO:0048752 18 0.012
response to uv GO:0009411 3 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.012
regulation of biological quality GO:0065008 263 0.011
post anal tail morphogenesis GO:0036342 19 0.011
development of primary female sexual characteristics GO:0046545 4 0.011
regulation of developmental growth GO:0048638 38 0.011
circulatory system process GO:0003013 87 0.011
female gonad development GO:0008585 4 0.011
multicellular organism growth GO:0035264 4 0.011
embryonic cranial skeleton morphogenesis GO:0048701 90 0.011
translational initiation GO:0006413 3 0.011
muscle cell development GO:0055001 115 0.011
organonitrogen compound biosynthetic process GO:1901566 47 0.011
nerve development GO:0021675 45 0.011
cognition GO:0050890 1 0.011
fin regeneration GO:0031101 51 0.011
Zebrafish
regulation of nucleic acid templated transcription GO:1903506 213 0.011
Zebrafish Fly
mesodermal cell differentiation GO:0048333 21 0.011
regulation of cell shape GO:0008360 1 0.011
convergent extension GO:0060026 118 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
regulation of mitotic cell cycle GO:0007346 25 0.011
gene silencing GO:0016458 4 0.011
ectodermal placode development GO:0071696 37 0.010
regulation of nucleocytoplasmic transport GO:0046822 2 0.010
peptide transport GO:0015833 1 0.010
positive regulation of signal transduction GO:0009967 56 0.010
negative regulation of histone modification GO:0031057 1 0.010
hypothalamus cell differentiation GO:0021979 4 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.010
Fly
negative regulation of dna metabolic process GO:0051053 4 0.010
sodium ion transport GO:0006814 24 0.010
mesenchymal cell development GO:0014031 78 0.010
negative chemotaxis GO:0050919 1 0.010
myotube differentiation GO:0014902 45 0.010

pou2f1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.015
disease of anatomical entity DOID:7 0 0.015
musculoskeletal system disease DOID:17 0 0.011
bone development disease DOID:0080006 0 0.011
connective tissue disease DOID:65 0 0.011
bone disease DOID:0080001 0 0.011