Danio rerio

148 known processes

pou5f1

POU domain, class 5, transcription factor 1

(Aliases: POU-2,cb197,oct4,pou2,gp9,spg/pou2,gp-9,chunp6868,wu:fd18d06)

pou5f1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
axial mesoderm formation GO:0048320 4 0.948
positive regulation of cellular process GO:0048522 201 0.946
anterior posterior pattern specification GO:0009952 152 0.937
cellular macromolecule metabolic process GO:0044260 391 0.928
protein metabolic process GO:0019538 183 0.902
meiosis ii GO:0007135 1 0.851
regulation of biosynthetic process GO:0009889 250 0.816
regulation of response to stimulus GO:0048583 269 0.777
cellular biosynthetic process GO:0044249 286 0.767
regulation of signal transduction GO:0009966 225 0.766
notochord development GO:0030903 54 0.760
cellular nitrogen compound metabolic process GO:0034641 290 0.755
generation of neurons GO:0048699 385 0.743
cell surface receptor signaling pathway GO:0007166 325 0.730
regulation of nucleic acid templated transcription GO:1903506 213 0.728
organic cyclic compound biosynthetic process GO:1901362 223 0.727
regulation of primary metabolic process GO:0080090 311 0.702
heart morphogenesis GO:0003007 156 0.700
digestive system development GO:0055123 289 0.696
regulation of multicellular organismal process GO:0051239 277 0.693
cell morphogenesis GO:0000902 289 0.675
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.671
regionalization GO:0003002 274 0.667
organelle organization GO:0006996 227 0.656
positive regulation of cellular metabolic process GO:0031325 94 0.641
appendage development GO:0048736 80 0.636
fertilization GO:0009566 3 0.635
gastrulation GO:0007369 208 0.634
rna biosynthetic process GO:0032774 181 0.628
regulation of multicellular organismal development GO:2000026 223 0.624
cell cycle process GO:0022402 53 0.611
diencephalon development GO:0021536 58 0.602
regulation of nitrogen compound metabolic process GO:0051171 251 0.598
canonical wnt signaling pathway GO:0060070 48 0.598
cell division GO:0051301 20 0.584
segmentation GO:0035282 97 0.573
head development GO:0060322 303 0.566
embryonic organ morphogenesis GO:0048562 274 0.553
nucleobase containing compound biosynthetic process GO:0034654 205 0.551
regulation of metabolic process GO:0019222 359 0.539
spindle assembly involved in meiosis GO:0090306 1 0.535
organic cyclic compound metabolic process GO:1901360 301 0.532
single organism organelle organization GO:1902589 199 0.529
regulation of biological quality GO:0065008 263 0.523
cellular protein metabolic process GO:0044267 129 0.518
nucleobase containing compound metabolic process GO:0006139 274 0.510
neuron development GO:0048666 262 0.510
cell fate commitment GO:0045165 99 0.495
meiosis i GO:0007127 1 0.487
regulation of macromolecule biosynthetic process GO:0010556 225 0.478
developmental maturation GO:0021700 34 0.475
aromatic compound biosynthetic process GO:0019438 217 0.469
regulation of developmental process GO:0050793 247 0.469
nitrogen compound metabolic process GO:0006807 319 0.468
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.458
gall bladder development GO:0061010 1 0.457
appendage morphogenesis GO:0035107 56 0.444
oocyte development GO:0048599 14 0.442
cellular component morphogenesis GO:0032989 336 0.431
transcription dna templated GO:0006351 181 0.425
digestive tract morphogenesis GO:0048546 231 0.405
regulation of gene expression GO:0010468 265 0.396
biosynthetic process GO:0009058 294 0.393
regulation of rna metabolic process GO:0051252 224 0.387
determination of left right symmetry GO:0007368 179 0.386
somitogenesis GO:0001756 87 0.360
aorta development GO:0035904 4 0.352
cell morphogenesis involved in differentiation GO:0000904 195 0.349
wnt signaling pathway GO:0016055 80 0.344
cellular response to growth factor stimulus GO:0071363 39 0.343
epithelial tube morphogenesis GO:0060562 148 0.341
brain development GO:0007420 293 0.339
neural tube patterning GO:0021532 33 0.338
neural tube development GO:0021915 62 0.331
vasculature development GO:0001944 278 0.330
digestive tract development GO:0048565 265 0.326
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.326
gene expression GO:0010467 252 0.320
spindle assembly involved in female meiosis GO:0007056 1 0.318
cellular nitrogen compound biosynthetic process GO:0044271 218 0.318
tube morphogenesis GO:0035239 349 0.318
single fertilization GO:0007338 3 0.313
locomotion GO:0040011 313 0.304
stem cell fate commitment GO:0048865 1 0.302
regulation of cellular biosynthetic process GO:0031326 245 0.287
regulation of signaling GO:0023051 235 0.285
reproduction GO:0000003 40 0.282
neuron differentiation GO:0030182 353 0.278
multi organism process GO:0051704 134 0.276
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.276
floor plate development GO:0033504 15 0.274
cellular macromolecule biosynthetic process GO:0034645 224 0.271
stem cell differentiation GO:0048863 117 0.265
embryonic axis specification GO:0000578 12 0.264
meiotic spindle organization GO:0000212 1 0.263
axis specification GO:0009798 43 0.262
morphogenesis of an epithelium GO:0002009 333 0.254
positive regulation of biological process GO:0048518 253 0.254
embryonic pattern specification GO:0009880 44 0.253
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.251
determination of heart left right asymmetry GO:0061371 117 0.250
positive regulation of programmed cell death GO:0043068 29 0.250
chordate embryonic development GO:0043009 271 0.248
specification of organ position GO:0010159 3 0.246
pronuclear migration GO:0035046 1 0.245
localization of cell GO:0051674 244 0.245
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.243
regulation of chromosome segregation GO:0051983 1 0.241
regulation of rna biosynthetic process GO:2001141 213 0.235
oocyte maturation GO:0001556 4 0.233
regulation of transcription dna templated GO:0006355 213 0.233
regulation of protein metabolic process GO:0051246 56 0.225
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.224
embryonic organ development GO:0048568 381 0.224
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.224
phosphorus metabolic process GO:0006793 109 0.223
rna metabolic process GO:0016070 219 0.220
pronephros development GO:0048793 69 0.219
positive regulation of translation GO:0045727 1 0.218
retina development in camera type eye GO:0060041 146 0.217
negative regulation of myeloid leukocyte differentiation GO:0002762 1 0.211
endoderm development GO:0007492 49 0.211
regulation of cellular metabolic process GO:0031323 320 0.211
somite development GO:0061053 96 0.208
enzyme linked receptor protein signaling pathway GO:0007167 106 0.207
positive regulation of macromolecule metabolic process GO:0010604 93 0.207
hematopoietic or lymphoid organ development GO:0048534 191 0.205
cellular response to organic substance GO:0071310 105 0.200
regulation of cell communication GO:0010646 232 0.197
negative regulation of cellular process GO:0048523 283 0.194
cell motility GO:0048870 244 0.192
heart looping GO:0001947 94 0.191
microtubule polymerization GO:0046785 2 0.191
cellular response to chemical stimulus GO:0070887 157 0.190
regulation of wnt signaling pathway GO:0030111 53 0.190
bmp signaling pathway involved in heart development GO:0061312 15 0.186
aorta morphogenesis GO:0035909 3 0.183
formation of primary germ layer GO:0001704 62 0.183
meiotic nuclear division GO:0007126 4 0.181
meiotic chromosome segregation GO:0045132 3 0.181
autophagy GO:0006914 4 0.181
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.178
female meiosis ii GO:0007147 1 0.178
cellular protein modification process GO:0006464 100 0.178
single organism transport GO:0044765 206 0.177
atrioventricular valve formation GO:0003190 3 0.174
positive regulation of transcription dna templated GO:0045893 57 0.174
determination of left right asymmetry in diencephalon GO:0035462 4 0.172
positive regulation of protein metabolic process GO:0051247 23 0.165
cell fate specification GO:0001708 68 0.165
maintenance of location GO:0051235 4 0.160
reproductive process GO:0022414 40 0.160
male meiosis GO:0007140 2 0.158
sexual reproduction GO:0019953 36 0.155
notch signaling pathway GO:0007219 35 0.152
axon development GO:0061564 166 0.151
stem cell development GO:0048864 82 0.146
mitotic cell cycle GO:0000278 64 0.146
limbic system development GO:0021761 16 0.142
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.142
organic substance biosynthetic process GO:1901576 289 0.142
axial mesodermal cell fate specification GO:0048327 3 0.141
protein modification process GO:0036211 100 0.141
cellular aromatic compound metabolic process GO:0006725 295 0.140
cell part morphogenesis GO:0032990 246 0.139
nucleic acid metabolic process GO:0090304 244 0.137
endoderm formation GO:0001706 29 0.135
spinal cord motor neuron differentiation GO:0021522 26 0.134
negative regulation of gliogenesis GO:0014014 1 0.133
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.132
catabolic process GO:0009056 32 0.131
positive regulation of biosynthetic process GO:0009891 68 0.131
germ line stem cell division GO:0042078 1 0.130
hemopoiesis GO:0030097 183 0.126
embryonic heart tube morphogenesis GO:0003143 108 0.124
notochord formation GO:0014028 6 0.124
epithelial cell development GO:0002064 42 0.122
mesendoderm development GO:0048382 10 0.121
signal transduction GO:0007165 455 0.120
blood vessel development GO:0001568 246 0.120
positive regulation of response to stimulus GO:0048584 80 0.118
urogenital system development GO:0001655 97 0.118
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.117
central nervous system development GO:0007417 387 0.116
oocyte construction GO:0007308 5 0.115
multicellular organism reproduction GO:0032504 35 0.112
positive regulation of signal transduction GO:0009967 56 0.112
regulation of wnt signaling pathway involved in dorsal ventral axis specification GO:2000053 5 0.111
regulation of macromolecule metabolic process GO:0060255 317 0.110
establishment of localization in cell GO:0051649 77 0.110
anterior posterior axis specification GO:0009948 20 0.109
macroautophagy GO:0016236 1 0.108
germ cell migration GO:0008354 8 0.107
positive regulation of cellular protein metabolic process GO:0032270 22 0.106
negative regulation of rna biosynthetic process GO:1902679 45 0.105
embryonic heart tube left right pattern formation GO:0060971 5 0.105
renal system development GO:0072001 94 0.105
proepicardium development GO:0003342 4 0.105
left right pattern formation GO:0060972 19 0.105
response to external stimulus GO:0009605 264 0.103
death GO:0016265 121 0.102
determination of left right asymmetry in nervous system GO:0035545 4 0.102
fin morphogenesis GO:0033334 53 0.101
response to other organism GO:0051707 97 0.101
stem cell proliferation GO:0072089 4 0.098
positive regulation of signaling GO:0023056 56 0.098
cell projection organization GO:0030030 284 0.098
endodermal digestive tract morphogenesis GO:0061031 2 0.098
regulation of retina development in camera type eye GO:1902866 2 0.095
cellular catabolic process GO:0044248 27 0.095
female meiotic division GO:0007143 2 0.095
cell cycle g1 s phase transition GO:0044843 1 0.093
rhombomere 5 morphogenesis GO:0021664 1 0.092
metencephalon development GO:0022037 27 0.092
camera type eye development GO:0043010 222 0.092
floor plate morphogenesis GO:0033505 12 0.091
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.091
ear development GO:0043583 127 0.090
mesoderm formation GO:0001707 43 0.090
blood vessel morphogenesis GO:0048514 216 0.090
positive regulation of cell cycle GO:0045787 3 0.090
dorsal ventral pattern formation GO:0009953 125 0.090
cell migration GO:0016477 237 0.089
floor plate formation GO:0021508 12 0.088
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.088
sensory organ development GO:0007423 393 0.088
mesoderm morphogenesis GO:0048332 51 0.087
embryonic appendage morphogenesis GO:0035113 30 0.087
phosphorylation GO:0016310 69 0.087
hormone metabolic process GO:0042445 19 0.086
pectoral fin development GO:0033339 50 0.086
single organism metabolic process GO:0044710 217 0.086
invagination involved in gastrulation with mouth forming second GO:0055109 1 0.085
microtubule based process GO:0007017 60 0.085
gamete generation GO:0007276 33 0.084
regulation of cellular protein metabolic process GO:0032268 52 0.084
convergent extension involved in gastrulation GO:0060027 71 0.084
nucleic acid templated transcription GO:0097659 181 0.082
hindbrain development GO:0030902 91 0.082
regulation of embryonic development GO:0045995 47 0.082
rostrocaudal neural tube patterning GO:0021903 29 0.082
response to stress GO:0006950 263 0.080
midbrain hindbrain boundary development GO:0030917 23 0.080
eye morphogenesis GO:0048592 144 0.079
cardiocyte differentiation GO:0035051 44 0.079
single organism membrane organization GO:0044802 20 0.078
sensory organ morphogenesis GO:0090596 200 0.078
cellular component movement GO:0006928 335 0.078
muscle organ development GO:0007517 101 0.078
germ cell development GO:0007281 22 0.078
heterocycle metabolic process GO:0046483 290 0.078
dorsal ventral axis specification GO:0009950 14 0.077
positive regulation of gene expression GO:0010628 71 0.076
positive regulation of transport GO:0051050 2 0.076
negative regulation of mesodermal cell fate specification GO:0042662 3 0.076
cell death GO:0008219 121 0.075
positive regulation of response to external stimulus GO:0032103 9 0.073
heart jogging GO:0003146 40 0.072
muscle structure development GO:0061061 196 0.071
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.071
apoptotic process GO:0006915 116 0.070
pole plasm assembly GO:0007315 4 0.070
axis elongation GO:0003401 31 0.070
regulation of endodermal cell fate specification GO:0042663 15 0.070
meiotic cell cycle process GO:1903046 3 0.069
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.069
neuron projection morphogenesis GO:0048812 161 0.069
immune system process GO:0002376 241 0.068
biological adhesion GO:0022610 40 0.067
oocyte axis specification GO:0007309 5 0.067
axis elongation involved in somitogenesis GO:0090245 2 0.067
cell maturation GO:0048469 23 0.066
regulation of canonical wnt signaling pathway GO:0060828 34 0.066
septum transversum development GO:0003343 4 0.066
heart field specification GO:0003128 1 0.065
programmed cell death GO:0012501 119 0.064
photoreceptor cell fate commitment GO:0046552 1 0.064
regulation of protein modification process GO:0031399 29 0.063
regulation of apoptotic process GO:0042981 98 0.063
embryonic limb morphogenesis GO:0030326 2 0.062
axial mesoderm development GO:0048318 10 0.062
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.061
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.061
cell cycle GO:0007049 93 0.061
negative regulation of cellular metabolic process GO:0031324 77 0.060
neuroblast differentiation GO:0014016 1 0.060
response to external biotic stimulus GO:0043207 97 0.060
regulation of organ morphogenesis GO:2000027 35 0.059
regulation of cell death GO:0010941 103 0.059
axial mesoderm morphogenesis GO:0048319 8 0.059
spindle assembly GO:0051225 2 0.058
cellular response to stress GO:0033554 62 0.058
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 9 0.057
negative regulation of cell death GO:0060548 60 0.057
regulation of protein catabolic process GO:0042176 1 0.057
negative regulation of biosynthetic process GO:0009890 55 0.057
negative regulation of signal transduction GO:0009968 94 0.057
cell proliferation GO:0008283 80 0.057
endodermal cell fate commitment GO:0001711 18 0.056
developmental process involved in reproduction GO:0003006 27 0.056
embryonic digestive tract morphogenesis GO:0048557 3 0.056
negative regulation of cellular biosynthetic process GO:0031327 55 0.056
positive regulation of chromosome segregation GO:0051984 1 0.056
oocyte anterior posterior axis specification GO:0007314 4 0.055
regulation of protein localization to nucleus GO:1900180 2 0.055
embryonic pectoral fin morphogenesis GO:0035118 24 0.055
heart development GO:0007507 313 0.055
regulation of cellular response to growth factor stimulus GO:0090287 35 0.055
cellular localization GO:0051641 97 0.055
blastoderm segmentation GO:0007350 6 0.054
anterior posterior axis specification embryo GO:0008595 5 0.054
stem cell division GO:0017145 1 0.053
pectoral fin morphogenesis GO:0035138 29 0.053
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.053
mesenchyme development GO:0060485 127 0.053
regulation of transferase activity GO:0051338 16 0.053
negative regulation of macromolecule metabolic process GO:0010605 76 0.053
canonical wnt signaling pathway involved in neural plate anterior posterior pattern formation GO:0060823 4 0.052
neuron fate specification GO:0048665 20 0.052
positive regulation of cellular catabolic process GO:0031331 3 0.052
cell projection morphogenesis GO:0048858 244 0.052
embryo development ending in birth or egg hatching GO:0009792 271 0.052
hepatic duct development GO:0061011 2 0.052
positive regulation of catabolic process GO:0009896 4 0.051
positive regulation of cellular biosynthetic process GO:0031328 68 0.051
negative regulation of gene expression GO:0010629 65 0.050
response to endogenous stimulus GO:0009719 83 0.050
spemann organizer formation at the embryonic shield GO:0060063 2 0.050
cardiac chamber development GO:0003205 19 0.049
transport GO:0006810 220 0.049
hepatocyte proliferation GO:0072574 2 0.049
inner ear development GO:0048839 126 0.049
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.049
outflow tract morphogenesis GO:0003151 1 0.049
negative regulation of biological process GO:0048519 304 0.048
negative regulation of transcription dna templated GO:0045892 45 0.048
regulation of meiotic cell cycle GO:0051445 1 0.047
cell migration involved in gastrulation GO:0042074 79 0.047
positive regulation of metabolic process GO:0009893 108 0.047
small molecule metabolic process GO:0044281 77 0.047
macromolecule biosynthetic process GO:0009059 227 0.047
larval development GO:0002164 2 0.045
positive regulation of secretion by cell GO:1903532 1 0.045
centrosome organization GO:0051297 1 0.044
lateral inhibition GO:0046331 1 0.044
blood circulation GO:0008015 87 0.043
spemann organizer formation GO:0060061 10 0.043
cell differentiation in spinal cord GO:0021515 40 0.043
striated muscle tissue development GO:0014706 110 0.042
negative regulation of mitosis GO:0045839 3 0.042
foregut morphogenesis GO:0007440 4 0.042
endodermal cell fate determination GO:0007493 2 0.042
cytokinesis GO:0000910 3 0.042
regulation of establishment of protein localization GO:0070201 4 0.041
macromolecular complex subunit organization GO:0043933 74 0.041
axial mesoderm structural organization GO:0048331 2 0.041
negative regulation of cell cycle process GO:0010948 9 0.041
morphogenesis of embryonic epithelium GO:0016331 30 0.041
neuron projection development GO:0031175 180 0.040
homeostatic process GO:0042592 142 0.040
organic substance catabolic process GO:1901575 28 0.040
hypothalamus development GO:0021854 14 0.040
bmp signaling pathway involved in heart jogging GO:0003303 14 0.039
myeloid cell differentiation GO:0030099 86 0.039
phosphate containing compound metabolic process GO:0006796 108 0.039
neuroblast proliferation GO:0007405 2 0.039
vasculogenesis GO:0001570 41 0.038
microtubule cytoskeleton organization GO:0000226 33 0.038
developmental growth involved in morphogenesis GO:0060560 86 0.038
positive regulation of cell communication GO:0010647 56 0.038
pancreas development GO:0031016 84 0.038
embryonic hemopoiesis GO:0035162 53 0.038
cardiac muscle tissue development GO:0048738 48 0.038
small gtpase mediated signal transduction GO:0007264 8 0.038
modification dependent protein catabolic process GO:0019941 3 0.037
determination of bilateral symmetry GO:0009855 204 0.037
gliogenesis GO:0042063 45 0.037
protein polymerization GO:0051258 4 0.037
regulation of heart morphogenesis GO:2000826 17 0.036
regulation of cell division GO:0051302 12 0.036
positive regulation of chromatin modification GO:1903310 1 0.036
carbohydrate derivative metabolic process GO:1901135 61 0.036
rna stabilization GO:0043489 4 0.036
nuclear transport GO:0051169 4 0.035
photoreceptor cell fate specification GO:0043704 1 0.035
regulation of posttranscriptional gene silencing GO:0060147 1 0.035
proteasomal protein catabolic process GO:0010498 2 0.034
mitotic cell cycle process GO:1903047 48 0.034
stem cell maintenance GO:0019827 4 0.034
regulation of glial cell differentiation GO:0045685 4 0.034
cytoskeleton organization GO:0007010 96 0.033
developmental programmed cell death GO:0010623 4 0.033
regulation of cell cycle process GO:0010564 20 0.032
response to bacterium GO:0009617 58 0.032
regulation of localization GO:0032879 104 0.032
regulation of cardiac muscle cell differentiation GO:2000725 1 0.032
regulation of molecular function GO:0065009 70 0.032
regulation of bmp signaling pathway GO:0030510 39 0.032
germ line stem cell maintenance GO:0030718 2 0.031
notochord morphogenesis GO:0048570 17 0.031
homologous chromosome segregation GO:0045143 1 0.031
negative regulation of chromosome organization GO:2001251 1 0.031
negative regulation of response to stimulus GO:0048585 104 0.031
muscle cell differentiation GO:0042692 139 0.031
negative regulation of nucleic acid templated transcription GO:1903507 45 0.030
response to fibroblast growth factor GO:0071774 22 0.030
response to growth factor GO:0070848 39 0.030
regulation of cytokine production GO:0001817 3 0.030
protein localization to microtubule cytoskeleton GO:0072698 1 0.030
regulation of gene silencing by rna GO:0060966 1 0.030
response to organic substance GO:0010033 153 0.029
positive regulation of rna biosynthetic process GO:1902680 57 0.029
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.029
intracellular signal transduction GO:0035556 85 0.029
negative regulation of intracellular protein transport GO:0090317 3 0.029
mitotic sister chromatid segregation GO:0000070 6 0.029
positive regulation of protein modification process GO:0031401 11 0.029
immune system development GO:0002520 191 0.029
regulation of protein phosphorylation GO:0001932 18 0.029
negative regulation of rna metabolic process GO:0051253 48 0.029
regulation of hormone levels GO:0010817 21 0.029
determination of dorsal identity GO:0048263 13 0.028
modification dependent macromolecule catabolic process GO:0043632 3 0.028
specification of organ identity GO:0010092 2 0.028
embryonic foregut morphogenesis GO:0048617 1 0.028
cell adhesion GO:0007155 40 0.028
axonogenesis GO:0007409 152 0.028
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.028
mesodermal cell fate specification GO:0007501 12 0.028
regulation of mitotic cell cycle GO:0007346 25 0.027
otic placode formation GO:0043049 23 0.027
positive regulation of cell death GO:0010942 29 0.027
nerve development GO:0021675 45 0.027
posttranscriptional regulation of gene expression GO:0010608 14 0.027
regulation of cell morphogenesis GO:0022604 42 0.027
macromolecule localization GO:0033036 54 0.027
regulation of cell cycle GO:0051726 52 0.027
heterocycle biosynthetic process GO:0018130 215 0.027
erythrocyte differentiation GO:0030218 54 0.026
determination of dorsal ventral asymmetry GO:0048262 34 0.026
skeletal system development GO:0001501 181 0.026
oocyte differentiation GO:0009994 14 0.026
translational initiation GO:0006413 3 0.026
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.026
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.026
mesodermal cell fate commitment GO:0001710 14 0.026
forebrain development GO:0030900 96 0.026
oligodendrocyte differentiation GO:0048709 23 0.025
cellular hormone metabolic process GO:0034754 19 0.025
negative regulation of mitotic cell cycle GO:0045930 11 0.025
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.025
anatomical structure arrangement GO:0048532 2 0.025
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.025
intracellular transport GO:0046907 32 0.025
embryonic neurocranium morphogenesis GO:0048702 15 0.025
response to biotic stimulus GO:0009607 97 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.024
establishment or maintenance of cell polarity GO:0007163 29 0.024
negative regulation of calcium dependent cell cell adhesion GO:0046588 1 0.024
regulation of mrna processing GO:0050684 3 0.024
endocrine system development GO:0035270 65 0.024
heart valve formation GO:0003188 4 0.024
establishment of localization GO:0051234 244 0.023
regulation of catalytic activity GO:0050790 55 0.023
positive regulation of secretion GO:0051047 1 0.023
negative regulation of translational initiation GO:0045947 1 0.023
cell proliferation involved in heart morphogenesis GO:0061323 2 0.023
apoptotic process involved in development GO:1902742 2 0.023
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.023
regulation of cell differentiation GO:0045595 142 0.023
negative regulation of cytoplasmic transport GO:1903650 2 0.023
establishment of organelle localization GO:0051656 45 0.022
notochord cell differentiation GO:0060034 18 0.022
microtubule organizing center organization GO:0031023 1 0.022
circulatory system process GO:0003013 87 0.022
negative regulation of cell cycle GO:0045786 14 0.022
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.022
dsrna fragmentation GO:0031050 1 0.022
response to metal ion GO:0010038 34 0.022
regulation of programmed cell death GO:0043067 101 0.022
g1 s transition of mitotic cell cycle GO:0000082 1 0.022
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.022
transcription from rna polymerase ii promoter GO:0006366 80 0.022
mitotic nuclear division GO:0007067 18 0.022
segment specification GO:0007379 12 0.022
mesoderm development GO:0007498 88 0.022
neuroblast fate commitment GO:0014017 1 0.022
calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules GO:0016339 2 0.022
segment polarity determination GO:0007367 1 0.022
cellular response to oxygen levels GO:0071453 1 0.022
chromosome segregation GO:0007059 12 0.022
regulation of mesodermal cell fate specification GO:0042661 9 0.022
skin development GO:0043588 54 0.021
bmp signaling pathway GO:0030509 52 0.021

pou5f1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.040
disease of cellular proliferation DOID:14566 0 0.040
reproductive organ cancer DOID:193 0 0.037
female reproductive organ cancer DOID:120 0 0.037
organ system cancer DOID:0050686 0 0.037