Danio rerio

0 known processes

ppdpfb

pancreatic progenitor cell differentiation and proliferation factor b

(Aliases: c20orf149b,wu:fj62f01,zgc:73395,c20orf149l)

ppdpfb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.136
hormone transport GO:0009914 2 0.107
regulation of biological quality GO:0065008 263 0.102
nuclear transport GO:0051169 4 0.091
regulation of protein localization to nucleus GO:1900180 2 0.090
regulation of protein transport GO:0051223 3 0.090
negative regulation of biological process GO:0048519 304 0.090
nucleocytoplasmic transport GO:0006913 4 0.088
regulation of hormone secretion GO:0046883 2 0.086
protein targeting to nucleus GO:0044744 3 0.078
maintenance of location GO:0051235 4 0.075
single organism nuclear import GO:1902593 3 0.074
glucose homeostasis GO:0042593 1 0.074
regulation of multicellular organism growth GO:0040014 4 0.063
nitrogen compound metabolic process GO:0006807 319 0.061
hormone secretion GO:0046879 2 0.060
positive regulation of transport GO:0051050 2 0.059
protein localization to nucleus GO:0034504 3 0.058
regulation of intracellular protein transport GO:0033157 3 0.057
programmed cell death GO:0012501 119 0.057
positive regulation of cell cycle GO:0045787 3 0.057
negative regulation of protein transport GO:0051224 3 0.057
cell surface receptor signaling pathway GO:0007166 325 0.057
response to chemical GO:0042221 320 0.055
regulation of response to stimulus GO:0048583 269 0.053
response to carbohydrate GO:0009743 3 0.052
establishment of protein localization to organelle GO:0072594 4 0.052
cellular response to chemical stimulus GO:0070887 157 0.050
determination of bilateral symmetry GO:0009855 204 0.048
regulation of cytoplasmic transport GO:1903649 4 0.048
regulation of primary metabolic process GO:0080090 311 0.048
negative regulation of cytoplasmic transport GO:1903650 2 0.047
positive regulation of secretion by cell GO:1903532 1 0.047
establishment of localization GO:0051234 244 0.046
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.045
response to monosaccharide GO:0034284 3 0.045
negative regulation of intracellular protein transport GO:0090317 3 0.044
regulation of cytokine production GO:0001817 3 0.044
response to stress GO:0006950 263 0.044
signal transduction GO:0007165 455 0.043
nuclear import GO:0051170 3 0.043
protein import GO:0017038 3 0.043
negative regulation of cellular process GO:0048523 283 0.043
protein import into nucleus GO:0006606 3 0.042
transport GO:0006810 220 0.042
single organism transport GO:0044765 206 0.042
immune system process GO:0002376 241 0.042
regulation of nucleocytoplasmic transport GO:0046822 2 0.041
aging GO:0007568 2 0.041
multicellular organism growth GO:0035264 4 0.040
positive regulation of biological process GO:0048518 253 0.040
system process GO:0003008 185 0.040
meiotic cell cycle process GO:1903046 3 0.038
negative regulation of protein localization to nucleus GO:1900181 2 0.038
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.038
stem cell maintenance GO:0019827 4 0.037
embryo development ending in birth or egg hatching GO:0009792 271 0.036
regulation of establishment of protein localization GO:0070201 4 0.036
regulation of developmental process GO:0050793 247 0.035
spermatid development GO:0007286 2 0.034
cellular response to biotic stimulus GO:0071216 3 0.034
embryonic organ development GO:0048568 381 0.034
sensory organ development GO:0007423 393 0.033
cellular amine metabolic process GO:0044106 2 0.033
homeostatic process GO:0042592 142 0.032
ion transport GO:0006811 114 0.032
negative regulation of intracellular transport GO:0032387 3 0.032
cellular ketone metabolic process GO:0042180 11 0.030
response to hexose GO:0009746 3 0.030
peptide transport GO:0015833 1 0.030
embryonic heart tube development GO:0035050 133 0.030
regulation of metal ion transport GO:0010959 4 0.029
regulation of skeletal muscle tissue development GO:0048641 4 0.029
photoreceptor cell fate commitment GO:0046552 1 0.029
lipid storage GO:0019915 1 0.029
response to ketone GO:1901654 1 0.029
regulation of multicellular organismal process GO:0051239 277 0.029
cellular component movement GO:0006928 335 0.029
neuron projection development GO:0031175 180 0.029
response to corticosteroid GO:0031960 1 0.029
ion transmembrane transport GO:0034220 91 0.028
regulation of binding GO:0051098 3 0.028
astrocyte differentiation GO:0048708 1 0.028
heart development GO:0007507 313 0.028
gtp metabolic process GO:0046039 4 0.028
cardiac atrium development GO:0003230 4 0.028
positive regulation of muscle cell differentiation GO:0051149 1 0.027
morphogenesis of an epithelium GO:0002009 333 0.027
neuron development GO:0048666 262 0.027
regulation of metabolic process GO:0019222 359 0.027
single fertilization GO:0007338 3 0.026
carbohydrate homeostasis GO:0033500 1 0.026
response to glucose GO:0009749 3 0.026
regulation of signaling GO:0023051 235 0.026
spermatid differentiation GO:0048515 2 0.025
regulation of synapse organization GO:0050807 3 0.025
regulation of protein targeting GO:1903533 2 0.025
negative regulation of sequestering of calcium ion GO:0051283 4 0.025
regulation of protein binding GO:0043393 3 0.025
organic cyclic compound metabolic process GO:1901360 301 0.025
cellular protein modification process GO:0006464 100 0.024
response to glucocorticoid GO:0051384 1 0.024
mitochondrion organization GO:0007005 4 0.024
compound eye development GO:0048749 2 0.024
adult behavior GO:0030534 2 0.024
tube morphogenesis GO:0035239 349 0.024
regulation of transmembrane transporter activity GO:0022898 2 0.024
response to organic substance GO:0010033 153 0.023
membrane fusion GO:0061025 2 0.023
inorganic ion transmembrane transport GO:0098660 57 0.023
negative regulation of kinase activity GO:0033673 4 0.023
regulation of carbohydrate metabolic process GO:0006109 4 0.023
cell death GO:0008219 121 0.023
regulation of cellular amine metabolic process GO:0033238 0 0.023
response to abiotic stimulus GO:0009628 122 0.023
positive regulation of nucleoside metabolic process GO:0045979 1 0.023
rna localization GO:0006403 4 0.023
regulation of synapse assembly GO:0051963 3 0.022
pigmentation GO:0043473 85 0.022
positive regulation of cellular catabolic process GO:0031331 3 0.022
nucleic acid templated transcription GO:0097659 181 0.022
regulation of signal transduction GO:0009966 225 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
positive regulation of cellular component biogenesis GO:0044089 3 0.022
cellular response to oxygen levels GO:0071453 1 0.022
negative regulation of protein phosphorylation GO:0001933 4 0.022
positive regulation of secretion GO:0051047 1 0.022
sequestering of metal ion GO:0051238 3 0.022
cellular response to external stimulus GO:0071496 2 0.022
sensory organ morphogenesis GO:0090596 200 0.022
negative regulation of response to stimulus GO:0048585 104 0.022
single organism membrane fusion GO:0044801 2 0.022
digestive tract development GO:0048565 265 0.022
regulation of protein import into nucleus GO:0042306 2 0.021
growth GO:0040007 174 0.021
organic acid metabolic process GO:0006082 31 0.021
single organism metabolic process GO:0044710 217 0.021
oxoacid metabolic process GO:0043436 31 0.021
organelle organization GO:0006996 227 0.021
response to uv GO:0009411 3 0.021
response to drug GO:0042493 3 0.021
sequestering of calcium ion GO:0051208 3 0.021
regulation of intracellular ph GO:0051453 1 0.020
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.020
regulation of nucleoside metabolic process GO:0009118 2 0.020
specification of symmetry GO:0009799 204 0.020
mesenchyme development GO:0060485 127 0.020
regulation of blood pressure GO:0008217 1 0.020
stem cell division GO:0017145 1 0.020
negative regulation of multicellular organismal process GO:0051241 69 0.020
amine metabolic process GO:0009308 2 0.020
determination of left right symmetry GO:0007368 179 0.020
cellular response to nutrient levels GO:0031669 2 0.020
regulation of skeletal muscle fiber development GO:0048742 2 0.020
regulation of stem cell differentiation GO:2000736 4 0.020
cellular response to starvation GO:0009267 1 0.020
positive regulation of cytokine production GO:0001819 2 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.019
nucleobase containing compound biosynthetic process GO:0034654 205 0.019
actin cytoskeleton organization GO:0030036 63 0.019
positive regulation of cellular process GO:0048522 201 0.019
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.019
aromatic compound biosynthetic process GO:0019438 217 0.019
regulation of nucleic acid templated transcription GO:1903506 213 0.019
single organism organelle organization GO:1902589 199 0.019
multi organism process GO:0051704 134 0.019
regulation of purine nucleotide catabolic process GO:0033121 2 0.019
regulation of oocyte development GO:0060281 3 0.019
regulation of ph GO:0006885 3 0.019
determination of heart left right asymmetry GO:0061371 117 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.019
cell cycle arrest GO:0007050 1 0.019
negative regulation of signal transduction GO:0009968 94 0.019
female sex differentiation GO:0046660 4 0.019
intra s dna damage checkpoint GO:0031573 1 0.019
organonitrogen compound metabolic process GO:1901564 74 0.019
negative regulation of protein import into nucleus GO:0042308 2 0.018
positive regulation of catabolic process GO:0009896 4 0.018
regulation of ion transmembrane transporter activity GO:0032412 2 0.018
regulation of sequestering of calcium ion GO:0051282 4 0.018
transmembrane transport GO:0055085 120 0.018
cell migration GO:0016477 237 0.018
regulation of cellular metabolic process GO:0031323 320 0.018
positive regulation of translation GO:0045727 1 0.018
b cell activation GO:0042113 2 0.018
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.018
positive regulation of gtp catabolic process GO:0033126 1 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.018
response to biotic stimulus GO:0009607 97 0.018
protein metabolic process GO:0019538 183 0.018
regulation of dna templated transcription in response to stress GO:0043620 0 0.018
digestive system development GO:0055123 289 0.018
Zebrafish
germ line stem cell maintenance GO:0030718 2 0.018
cortical actin cytoskeleton organization GO:0030866 1 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
protein acetylation GO:0006473 2 0.017
regionalization GO:0003002 274 0.017
response to alkaloid GO:0043279 2 0.017
cellular macromolecule metabolic process GO:0044260 391 0.017
cell projection organization GO:0030030 284 0.017
calcium ion transport into cytosol GO:0060402 3 0.017
regulation of cell shape GO:0008360 1 0.017
cell aging GO:0007569 2 0.017
regulation of localization GO:0032879 104 0.017
positive regulation of immune effector process GO:0002699 3 0.017
blood vessel morphogenesis GO:0048514 216 0.017
response to other organism GO:0051707 97 0.017
cognition GO:0050890 1 0.017
immune system development GO:0002520 191 0.017
generation of neurons GO:0048699 385 0.016
golgi vesicle transport GO:0048193 3 0.016
circadian regulation of gene expression GO:0032922 8 0.016
blood circulation GO:0008015 87 0.016
exocytosis GO:0006887 1 0.016
developmental growth GO:0048589 166 0.016
synaptic growth at neuromuscular junction GO:0051124 2 0.016
positive regulation of gtpase activity GO:0043547 1 0.016
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.016
regulation of glial cell differentiation GO:0045685 4 0.016
cellular nitrogen compound metabolic process GO:0034641 290 0.016
cytosolic calcium ion transport GO:0060401 3 0.016
cellular response to decreased oxygen levels GO:0036294 1 0.016
multicellular organismal signaling GO:0035637 22 0.016
peptidyl lysine acetylation GO:0018394 2 0.016
cell migration involved in heart formation GO:0060974 10 0.016
stem cell differentiation GO:0048863 117 0.016
phosphorylation GO:0016310 69 0.015
regulation of macromolecule metabolic process GO:0060255 317 0.015
membrane invagination GO:0010324 1 0.015
cellular protein metabolic process GO:0044267 129 0.015
blood vessel development GO:0001568 246 0.015
chordate embryonic development GO:0043009 271 0.015
regulation of nucleotide catabolic process GO:0030811 2 0.015
cardiac atrium morphogenesis GO:0003209 2 0.015
regulation of cell communication GO:0010646 232 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
epithelial tube morphogenesis GO:0060562 148 0.015
positive regulation of glial cell differentiation GO:0045687 1 0.015
striated muscle cell differentiation GO:0051146 129 0.015
response to oxygen levels GO:0070482 25 0.015
ventricular cardiac muscle tissue development GO:0003229 3 0.015
endocrine process GO:0050886 2 0.015
angiogenesis GO:0001525 158 0.014
negative regulation of synapse assembly GO:0051964 2 0.014
muscle structure development GO:0061061 196 0.014
cellular localization GO:0051641 97 0.014
meiotic chromosome segregation GO:0045132 3 0.014
cellular component assembly GO:0022607 170 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
regulation of cellular ph GO:0030641 1 0.014
cellular response to radiation GO:0071478 4 0.014
positive regulation of gliogenesis GO:0014015 2 0.014
regulation of cell development GO:0060284 100 0.014
establishment of endothelial barrier GO:0061028 3 0.014
regulation of transporter activity GO:0032409 2 0.014
cellular response to hypoxia GO:0071456 1 0.014
regulation of protein metabolic process GO:0051246 56 0.014
regulation of systemic arterial blood pressure GO:0003073 1 0.014
regulation of neuron migration GO:2001222 2 0.014
neuron differentiation GO:0030182 353 0.014
muscle cell development GO:0055001 115 0.014
endosomal transport GO:0016197 2 0.014
regulation of muscle contraction GO:0006937 3 0.014
transcription dna templated GO:0006351 181 0.013
negative regulation of i kappab kinase nf kappab signaling GO:0043124 1 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
lymphocyte proliferation GO:0046651 1 0.013
apoptotic process GO:0006915 116 0.013
hemopoiesis GO:0030097 183 0.013
phosphate containing compound metabolic process GO:0006796 108 0.013
response to nicotine GO:0035094 2 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.013
gland development GO:0048732 143 0.013
negative regulation of blood circulation GO:1903523 2 0.013
entrainment of circadian clock GO:0009649 2 0.013
cellular homeostasis GO:0019725 26 0.013
positive regulation of developmental process GO:0051094 50 0.013
stem cell proliferation GO:0072089 4 0.013
post golgi vesicle mediated transport GO:0006892 1 0.013
regulation of cellular component organization GO:0051128 86 0.013
cerebellar granular layer development GO:0021681 3 0.013
positive regulation of leukocyte differentiation GO:1902107 1 0.013
fertilization GO:0009566 3 0.013
embryonic organ morphogenesis GO:0048562 274 0.013
regulation of cell activation GO:0050865 1 0.013
gtp catabolic process GO:0006184 2 0.012
enzyme linked receptor protein signaling pathway GO:0007167 106 0.012
photoreceptor cell fate specification GO:0043704 1 0.012
autophagy GO:0006914 4 0.012
nucleic acid transport GO:0050657 2 0.012
eye development GO:0001654 277 0.012
rna biosynthetic process GO:0032774 181 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
organic substance transport GO:0071702 58 0.012
cytoskeleton dependent cytokinesis GO:0061640 3 0.012
regulation of receptor activity GO:0010469 2 0.012
heart morphogenesis GO:0003007 156 0.012
positive regulation of protein complex assembly GO:0031334 2 0.012
cellular component morphogenesis GO:0032989 336 0.012
heterocycle metabolic process GO:0046483 290 0.012
neuron remodeling GO:0016322 1 0.012
immunoglobulin mediated immune response GO:0016064 3 0.012
inositol lipid mediated signaling GO:0048017 2 0.012
negative regulation of signaling GO:0023057 96 0.012
intracellular mrna localization GO:0008298 1 0.012
retina development in camera type eye GO:0060041 146 0.012
macromolecule modification GO:0043412 111 0.012
regulation of calcium ion transport GO:0051924 2 0.012
organic cyclic compound biosynthetic process GO:1901362 223 0.012
negative regulation of cell communication GO:0010648 96 0.012
regulation of multicellular organismal development GO:2000026 223 0.012
digestive tract morphogenesis GO:0048546 231 0.012
cell cycle g2 m phase transition GO:0044839 4 0.012
negative regulation of protein kinase activity GO:0006469 4 0.012
locomotor rhythm GO:0045475 3 0.012
regulation of biosynthetic process GO:0009889 250 0.012
regulation of catalytic activity GO:0050790 55 0.012
phagocytosis GO:0006909 3 0.012
protein acylation GO:0043543 3 0.012
b cell mediated immunity GO:0019724 3 0.012
antimicrobial humoral response GO:0019730 2 0.012
centrosome organization GO:0051297 1 0.012
regulation of transcription involved in cell fate commitment GO:0060850 1 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
positive regulation of response to stimulus GO:0048584 80 0.012
regulation of gtpase activity GO:0043087 2 0.012
pole plasm assembly GO:0007315 4 0.012
macroautophagy GO:0016236 1 0.012
cation transmembrane transport GO:0098655 65 0.012
locomotion GO:0040011 313 0.012
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.012
zymogen activation GO:0031638 3 0.012
cellular carbohydrate metabolic process GO:0044262 4 0.011
cortical cytoskeleton organization GO:0030865 1 0.011
actin filament based process GO:0030029 64 0.011
thermosensory behavior GO:0040040 1 0.011
lipid homeostasis GO:0055088 3 0.011
biosynthetic process GO:0009058 294 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.011
regulation of molecular function GO:0065009 70 0.011
actin mediated cell contraction GO:0070252 1 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
cellular nitrogen compound biosynthetic process GO:0044271 218 0.011
cellular biosynthetic process GO:0044249 286 0.011
aorta morphogenesis GO:0035909 3 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
heart looping GO:0001947 94 0.011
cellular protein localization GO:0034613 20 0.011
muscle fiber development GO:0048747 52 0.011
cellular aromatic compound metabolic process GO:0006725 295 0.011
central nervous system development GO:0007417 387 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
female gonad development GO:0008585 4 0.011
regulation of circadian rhythm GO:0042752 4 0.011
regulation of gene expression GO:0010468 265 0.011
phagocytosis engulfment GO:0006911 1 0.011
death GO:0016265 121 0.011
cell morphogenesis GO:0000902 289 0.011
nuclear export GO:0051168 1 0.011
macromolecule biosynthetic process GO:0009059 227 0.011
regulation of endothelial cell differentiation GO:0045601 3 0.011
response to oxygen containing compound GO:1901700 55 0.011
eye morphogenesis GO:0048592 144 0.011
regulation of protein catabolic process GO:0042176 1 0.011
small molecule metabolic process GO:0044281 77 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
synaptic vesicle transport GO:0048489 1 0.011
leukocyte proliferation GO:0070661 1 0.011
protein dephosphorylation GO:0006470 3 0.011
taxis GO:0042330 109 0.011
cellular response to organic substance GO:0071310 105 0.011
cell migration to the midline involved in heart development GO:0003318 12 0.011
regulation of myotube differentiation GO:0010830 2 0.011
cellular response to hormone stimulus GO:0032870 39 0.011
heart contraction GO:0060047 71 0.011
axon ensheathment in central nervous system GO:0032291 2 0.011
meiosis i GO:0007127 1 0.011
lamellipodium organization GO:0097581 1 0.011
b cell differentiation GO:0030183 1 0.010
tissue regeneration GO:0042246 74 0.010
oocyte maturation GO:0001556 4 0.010
carboxylic acid metabolic process GO:0019752 22 0.010
guanosine containing compound catabolic process GO:1901069 2 0.010
negative regulation of macromolecule metabolic process GO:0010605 76 0.010
pancreas development GO:0031016 84 0.010
Zebrafish
regulation of reactive oxygen species metabolic process GO:2000377 2 0.010
negative regulation of metabolic process GO:0009892 86 0.010
regulation of cell death GO:0010941 103 0.010
meiotic nuclear division GO:0007126 4 0.010
regulation of response to extracellular stimulus GO:0032104 1 0.010
proteasomal protein catabolic process GO:0010498 2 0.010
glial cell migration GO:0008347 3 0.010
intracellular signal transduction GO:0035556 85 0.010
regulation of meiotic cell cycle GO:0051445 1 0.010
interaction with host GO:0051701 4 0.010
cellular component biogenesis GO:0044085 178 0.010
regulation of neurotransmitter secretion GO:0046928 1 0.010
cytoplasm organization GO:0007028 4 0.010

ppdpfb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.060
nervous system disease DOID:863 0 0.043
musculoskeletal system disease DOID:17 0 0.012
muscle tissue disease DOID:66 0 0.011
myopathy DOID:423 0 0.011
muscular disease DOID:0080000 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011
charcot marie tooth disease DOID:10595 0 0.011
neuromuscular disease DOID:440 0 0.011
charcot marie tooth disease type 4 DOID:0050541 0 0.011
neuropathy DOID:870 0 0.011
sensory system disease DOID:0050155 0 0.010
eye and adnexa disease DOID:1492 0 0.010