Danio rerio

7 known processes

ppial

peptidylprolyl isomerase A, like

(Aliases: zgc:73102,zgc:86688,wu:fj18g05)

ppial biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 2 0.454
maintenance of location GO:0051235 4 0.175
larval development GO:0002164 2 0.125
pronuclear migration GO:0035046 1 0.121
cellular macromolecule metabolic process GO:0044260 391 0.120
cellular nitrogen compound metabolic process GO:0034641 290 0.114
transport GO:0006810 220 0.099
signal transduction GO:0007165 455 0.091
regulation of cellular metabolic process GO:0031323 320 0.091
regulation of metabolic process GO:0019222 359 0.088
cell cycle GO:0007049 93 0.086
single organism organelle organization GO:1902589 199 0.086
actin filament polymerization GO:0030041 2 0.082
phagocytosis GO:0006909 3 0.081
lipid storage GO:0019915 1 0.077
cellular aromatic compound metabolic process GO:0006725 295 0.073
nucleobase containing compound metabolic process GO:0006139 274 0.072
regulation of biological quality GO:0065008 263 0.072
cell migration GO:0016477 237 0.071
cellular response to lipopolysaccharide GO:0071222 3 0.070
protein polymerization GO:0051258 4 0.068
organic cyclic compound metabolic process GO:1901360 301 0.068
phagocytosis engulfment GO:0006911 1 0.068
cellular component movement GO:0006928 335 0.063
positive regulation of cellular component biogenesis GO:0044089 3 0.060
intracellular signal transduction GO:0035556 85 0.058
heterocycle metabolic process GO:0046483 290 0.056
nuclear migration GO:0007097 3 0.053
organelle organization GO:0006996 227 0.053
regulation of nitrogen compound metabolic process GO:0051171 251 0.051
centrosome organization GO:0051297 1 0.051
regulation of protein complex assembly GO:0043254 3 0.049
central nervous system development GO:0007417 387 0.049
regulation of primary metabolic process GO:0080090 311 0.048
response to stress GO:0006950 263 0.048
negative regulation of protein complex assembly GO:0031333 1 0.047
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.047
regulation of protein polymerization GO:0032271 2 0.046
gene expression GO:0010467 252 0.045
nitrogen compound metabolic process GO:0006807 319 0.045
single fertilization GO:0007338 3 0.044
mitotic cell cycle GO:0000278 64 0.043
spermatid development GO:0007286 2 0.043
cellular protein metabolic process GO:0044267 129 0.042
cell motility GO:0048870 244 0.042
homeostatic process GO:0042592 142 0.042
microtubule organizing center organization GO:0031023 1 0.041
mitotic cell cycle process GO:1903047 48 0.041
cell surface receptor signaling pathway GO:0007166 325 0.041
modification dependent macromolecule catabolic process GO:0043632 3 0.039
protein metabolic process GO:0019538 183 0.039
negative regulation of cellular process GO:0048523 283 0.039
single organism transport GO:0044765 206 0.039
regulation of macromolecule metabolic process GO:0060255 317 0.038
embryo development ending in birth or egg hatching GO:0009792 271 0.038
regulation of signaling GO:0023051 235 0.038
proteasomal protein catabolic process GO:0010498 2 0.038
phosphorus metabolic process GO:0006793 109 0.036
pole plasm assembly GO:0007315 4 0.036
locomotion GO:0040011 313 0.035
cellular macromolecule biosynthetic process GO:0034645 224 0.034
centrosome duplication GO:0051298 1 0.034
single organism metabolic process GO:0044710 217 0.033
cognition GO:0050890 1 0.033
leukocyte homeostasis GO:0001776 2 0.033
cellular protein modification process GO:0006464 100 0.033
positive regulation of cytoskeleton organization GO:0051495 3 0.033
small molecule metabolic process GO:0044281 77 0.032
actin polymerization or depolymerization GO:0008154 2 0.031
positive regulation of cellular process GO:0048522 201 0.031
regulation of cellular amine metabolic process GO:0033238 0 0.030
mitotic cell cycle embryonic GO:0045448 2 0.030
cytoskeleton organization GO:0007010 96 0.029
multi organism process GO:0051704 134 0.029
regulation of signal transduction GO:0009966 225 0.028
regulation of multicellular organismal process GO:0051239 277 0.027
organic cyclic compound biosynthetic process GO:1901362 223 0.027
cellular response to molecule of bacterial origin GO:0071219 3 0.026
transcription dna templated GO:0006351 181 0.026
gtp metabolic process GO:0046039 4 0.026
nucleobase containing compound biosynthetic process GO:0034654 205 0.026
protein complex subunit organization GO:0071822 46 0.026
microtubule cytoskeleton organization GO:0000226 33 0.026
regulation of catalytic activity GO:0050790 55 0.026
ubiquitin dependent protein catabolic process GO:0006511 3 0.026
cell cycle process GO:0022402 53 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
regulation of programmed cell death GO:0043067 101 0.025
peptidyl serine phosphorylation GO:0018105 1 0.025
cell morphogenesis GO:0000902 289 0.025
establishment of localization GO:0051234 244 0.025
negative regulation of nuclear division GO:0051784 3 0.025
positive regulation of apoptotic signaling pathway GO:2001235 1 0.025
negative regulation of biological process GO:0048519 304 0.025
regulation of cellular ketone metabolic process GO:0010565 7 0.025
positive regulation of transport GO:0051050 2 0.024
regulation of gene expression GO:0010468 265 0.024
cellular amine metabolic process GO:0044106 2 0.024
establishment of protein localization to organelle GO:0072594 4 0.024
protein localization to nucleus GO:0034504 3 0.023
nucleic acid metabolic process GO:0090304 244 0.023
nucleocytoplasmic transport GO:0006913 4 0.023
organelle fission GO:0048285 23 0.023
cell death in response to oxidative stress GO:0036473 2 0.023
regulation of molecular function GO:0065009 70 0.023
regulation of cell communication GO:0010646 232 0.023
localization of cell GO:0051674 244 0.022
protein import GO:0017038 3 0.022
macromolecular complex subunit organization GO:0043933 74 0.022
protein modification process GO:0036211 100 0.022
glucose homeostasis GO:0042593 1 0.022
amine metabolic process GO:0009308 2 0.022
protein complex assembly GO:0006461 30 0.022
extrinsic apoptotic signaling pathway GO:0097191 3 0.022
regulation of cellular response to oxidative stress GO:1900407 2 0.021
adherens junction organization GO:0034332 4 0.021
cellular localization GO:0051641 97 0.021
positive regulation of secretion GO:0051047 1 0.021
regulation of homeostatic process GO:0032844 9 0.021
hemopoiesis GO:0030097 183 0.021
microtubule based process GO:0007017 60 0.021
cellular component disassembly GO:0022411 1 0.021
translational initiation GO:0006413 3 0.021
programmed cell death GO:0012501 119 0.021
Fly
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.020
regulation of establishment of protein localization GO:0070201 4 0.020
adult behavior GO:0030534 2 0.020
oocyte anterior posterior axis specification GO:0007314 4 0.020
protein import into nucleus GO:0006606 3 0.020
cytokinesis GO:0000910 3 0.020
lymphocyte homeostasis GO:0002260 1 0.020
cellular component assembly GO:0022607 170 0.020
brain development GO:0007420 293 0.019
nucleoside monophosphate catabolic process GO:0009125 4 0.019
macromolecule biosynthetic process GO:0009059 227 0.019
regulation of apoptotic process GO:0042981 98 0.019
positive regulation of biological process GO:0048518 253 0.019
regulation of cell differentiation GO:0045595 142 0.018
spermatid differentiation GO:0048515 2 0.018
cell morphogenesis involved in differentiation GO:0000904 195 0.018
regulation of erk1 and erk2 cascade GO:0070372 4 0.018
regulation of nucleoside metabolic process GO:0009118 2 0.018
organonitrogen compound metabolic process GO:1901564 74 0.018
carbohydrate derivative metabolic process GO:1901135 61 0.018
phosphate containing compound metabolic process GO:0006796 108 0.018
positive regulation of map kinase activity GO:0043406 3 0.017
positive regulation of nucleoside metabolic process GO:0045979 1 0.017
actin cytoskeleton organization GO:0030036 63 0.017
guanosine containing compound metabolic process GO:1901068 4 0.017
regulation of macromolecule biosynthetic process GO:0010556 225 0.017
macromolecular complex disassembly GO:0032984 1 0.017
carbohydrate homeostasis GO:0033500 1 0.017
blood vessel development GO:0001568 246 0.017
protein complex disassembly GO:0043241 1 0.017
autophagy GO:0006914 4 0.017
macromolecular complex assembly GO:0065003 35 0.017
head development GO:0060322 303 0.017
regulation of transcription dna templated GO:0006355 213 0.017
cellular ketone metabolic process GO:0042180 11 0.017
meiotic nuclear division GO:0007126 4 0.017
cell death GO:0008219 121 0.016
Fly
gtp catabolic process GO:0006184 2 0.016
protein targeting to nucleus GO:0044744 3 0.016
positive regulation of cytokine production GO:0001819 2 0.016
single organism nuclear import GO:1902593 3 0.016
organic acid metabolic process GO:0006082 31 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
phosphorylation GO:0016310 69 0.016
generation of neurons GO:0048699 385 0.016
regulation of rna metabolic process GO:0051252 224 0.016
centrosome cycle GO:0007098 1 0.016
regulation of protein ubiquitination GO:0031396 3 0.016
cellular carbohydrate metabolic process GO:0044262 4 0.016
peptidyl serine modification GO:0018209 2 0.016
positive regulation of stress activated mapk cascade GO:0032874 3 0.016
atp catabolic process GO:0006200 4 0.016
regulation of mrna processing GO:0050684 3 0.016
regulation of multicellular organism growth GO:0040014 4 0.015
regulation of cytokine production GO:0001817 3 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
cellular response to biotic stimulus GO:0071216 3 0.015
regulation of protein transport GO:0051223 3 0.015
single organism localization GO:1902578 225 0.015
aromatic compound biosynthetic process GO:0019438 217 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
meiotic cell cycle process GO:1903046 3 0.015
heterocycle biosynthetic process GO:0018130 215 0.015
regulation of response to stimulus GO:0048583 269 0.015
cell cycle g1 s phase transition GO:0044843 1 0.015
regulation of gtp catabolic process GO:0033124 2 0.015
positive regulation of ras protein signal transduction GO:0046579 1 0.015
regulation of biosynthetic process GO:0009889 250 0.015
cell projection organization GO:0030030 284 0.014
cytoskeleton dependent cytokinesis GO:0061640 3 0.014
regulation of protein complex disassembly GO:0043244 1 0.014
chordate embryonic development GO:0043009 271 0.014
nuclear transport GO:0051169 4 0.014
purine nucleotide metabolic process GO:0006163 27 0.014
organelle localization GO:0051640 49 0.014
multicellular organism growth GO:0035264 4 0.014
regulation of response to oxidative stress GO:1902882 2 0.014
protein secretion GO:0009306 1 0.014
neuron differentiation GO:0030182 353 0.014
leukocyte proliferation GO:0070661 1 0.014
regulation of cellular protein metabolic process GO:0032268 52 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
fertilization GO:0009566 3 0.014
positive regulation of cellular catabolic process GO:0031331 3 0.014
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.013
cell aging GO:0007569 2 0.013
positive regulation of signaling GO:0023056 56 0.013
specification of axis polarity GO:0065001 4 0.013
regulation of gtpase activity GO:0043087 2 0.013
rna metabolic process GO:0016070 219 0.013
oxoacid metabolic process GO:0043436 31 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.013
positive regulation of protein complex assembly GO:0031334 2 0.013
ion transport GO:0006811 114 0.013
establishment of cell polarity GO:0030010 18 0.013
regulation of cell activation GO:0050865 1 0.013
regulation of metal ion transport GO:0010959 4 0.013
establishment of organelle localization GO:0051656 45 0.013
biosynthetic process GO:0009058 294 0.013
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.013
morphogenesis of an epithelium GO:0002009 333 0.013
regulation of oxidative stress induced cell death GO:1903201 2 0.012
production of molecular mediator of immune response GO:0002440 2 0.012
protein depolymerization GO:0051261 1 0.012
ras protein signal transduction GO:0007265 7 0.012
small gtpase mediated signal transduction GO:0007264 8 0.012
g1 s transition of mitotic cell cycle GO:0000082 1 0.012
positive regulation of metabolic process GO:0009893 108 0.012
response to hydrogen peroxide GO:0042542 3 0.012
positive regulation of catabolic process GO:0009896 4 0.012
death GO:0016265 121 0.012
Fly
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
stem cell maintenance GO:0019827 4 0.012
regulation of nucleotide catabolic process GO:0030811 2 0.012
regulation of intracellular signal transduction GO:1902531 57 0.012
eye development GO:0001654 277 0.012
midbrain development GO:0030901 28 0.012
response to abiotic stimulus GO:0009628 122 0.012
regulation of translational initiation GO:0006446 1 0.012
positive regulation of macromolecule metabolic process GO:0010604 93 0.012
positive regulation of cellular metabolic process GO:0031325 94 0.012
rna biosynthetic process GO:0032774 181 0.012
lipid homeostasis GO:0055088 3 0.012
response to glucose GO:0009749 3 0.012
metal ion transport GO:0030001 58 0.012
sensory organ development GO:0007423 393 0.012
cellular component morphogenesis GO:0032989 336 0.012
cellular response to dna damage stimulus GO:0006974 24 0.011
camera type eye development GO:0043010 222 0.011
regulation of purine nucleotide catabolic process GO:0033121 2 0.011
negative regulation of mitosis GO:0045839 3 0.011
purine ribonucleoside biosynthetic process GO:0046129 2 0.011
regulation of erythrocyte differentiation GO:0045646 2 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
tube morphogenesis GO:0035239 349 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
response to chemical GO:0042221 320 0.011
establishment of localization in cell GO:0051649 77 0.011
cellular component biogenesis GO:0044085 178 0.011
regionalization GO:0003002 274 0.011
nuclear import GO:0051170 3 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
regulation of immune system process GO:0002682 34 0.011
retina development in camera type eye GO:0060041 146 0.011
response to organic substance GO:0010033 153 0.011
ameboidal type cell migration GO:0001667 143 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
positive regulation of immune effector process GO:0002699 3 0.010
negative regulation of macromolecule metabolic process GO:0010605 76 0.010
positive regulation of response to stimulus GO:0048584 80 0.010
developmental growth GO:0048589 166 0.010
immune system process GO:0002376 241 0.010

ppial disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.074
nervous system disease DOID:863 0 0.020