Danio rerio

0 known processes

ppib

peptidylprolyl isomerase B (cyclophilin B)

(Aliases: cb87,zgc:73214,zgc:86796,sb:cb87,wu:fa97f08)

ppib biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to organic cyclic compound GO:0071407 38 0.227
cellular response to estrogen stimulus GO:0071391 24 0.190
regulation of metal ion transport GO:0010959 4 0.176
collagen metabolic process GO:0032963 2 0.124
protein n linked glycosylation GO:0006487 1 0.110
maintenance of location GO:0051235 4 0.105
cytokinesis GO:0000910 3 0.097
cellular response to chemical stimulus GO:0070887 157 0.090
taxis GO:0042330 109 0.079
larval development GO:0002164 2 0.075
regulation of multicellular organism growth GO:0040014 4 0.075
cellular component morphogenesis GO:0032989 336 0.070
macromolecule biosynthetic process GO:0009059 227 0.069
aging GO:0007568 2 0.069
positive regulation of biological process GO:0048518 253 0.068
hydrogen peroxide metabolic process GO:0042743 2 0.067
regulation of biological quality GO:0065008 263 0.058
regulation of transcription dna templated GO:0006355 213 0.057
iron ion transmembrane transport GO:0034755 3 0.056
response to chemical GO:0042221 320 0.055
multicellular organismal macromolecule metabolic process GO:0044259 2 0.054
lipid storage GO:0019915 1 0.053
cellular macromolecule metabolic process GO:0044260 391 0.052
response to steroid hormone GO:0048545 35 0.047
cellular nitrogen compound biosynthetic process GO:0044271 218 0.047
single organism metabolic process GO:0044710 217 0.047
morphogenesis of an epithelium GO:0002009 333 0.047
negative regulation of gene expression GO:0010629 65 0.046
organonitrogen compound metabolic process GO:1901564 74 0.045
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.044
lateral inhibition GO:0046331 1 0.043
locomotion GO:0040011 313 0.043
oxoacid metabolic process GO:0043436 31 0.042
cellular response to unfolded protein GO:0034620 2 0.042
apoptotic process GO:0006915 116 0.042
organic substance biosynthetic process GO:1901576 289 0.042
golgi vesicle transport GO:0048193 3 0.041
cellular response to lipid GO:0071396 39 0.040
regulation of cellular biosynthetic process GO:0031326 245 0.038
cellular nitrogen compound metabolic process GO:0034641 290 0.037
cellular macromolecule biosynthetic process GO:0034645 224 0.037
epithelial cell morphogenesis GO:0003382 2 0.036
cellular response to steroid hormone stimulus GO:0071383 31 0.035
cellular response to hormone stimulus GO:0032870 39 0.034
cell death GO:0008219 121 0.034
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.034
positive regulation of protein complex assembly GO:0031334 2 0.033
multicellular organism growth GO:0035264 4 0.033
amine metabolic process GO:0009308 2 0.032
regulation of nitrogen compound metabolic process GO:0051171 251 0.032
nitrogen compound metabolic process GO:0006807 319 0.031
rna biosynthetic process GO:0032774 181 0.031
positive regulation of transport GO:0051050 2 0.031
organic cyclic compound metabolic process GO:1901360 301 0.031
cellular protein modification process GO:0006464 100 0.030
adult behavior GO:0030534 2 0.030
nucleobase containing compound biosynthetic process GO:0034654 205 0.030
heterocycle biosynthetic process GO:0018130 215 0.030
gene expression GO:0010467 252 0.029
regulation of rna metabolic process GO:0051252 224 0.029
transcription dna templated GO:0006351 181 0.029
cellular biosynthetic process GO:0044249 286 0.029
macromolecule modification GO:0043412 111 0.028
negative regulation of biological process GO:0048519 304 0.028
cellular response to reactive oxygen species GO:0034614 2 0.028
regulation of reproductive process GO:2000241 4 0.028
nucleic acid metabolic process GO:0090304 244 0.027
regulation of gene expression GO:0010468 265 0.027
cell morphogenesis GO:0000902 289 0.026
response to hormone GO:0009725 48 0.026
chromosome organization involved in meiosis GO:0070192 1 0.026
cell surface receptor signaling pathway GO:0007166 325 0.026
response to organic cyclic compound GO:0014070 51 0.026
response to estrogen GO:0043627 27 0.026
sensory organ development GO:0007423 393 0.025
response to lipid GO:0033993 60 0.025
response to external stimulus GO:0009605 264 0.025
response to endogenous stimulus GO:0009719 83 0.025
embryo development ending in birth or egg hatching GO:0009792 271 0.024
regulation of cellular metabolic process GO:0031323 320 0.024
chordate embryonic development GO:0043009 271 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.023
protein modification process GO:0036211 100 0.023
endoplasmic reticulum unfolded protein response GO:0030968 2 0.023
multi organism reproductive process GO:0044703 36 0.022
response to hydrogen peroxide GO:0042542 3 0.022
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.022
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.022
extrinsic apoptotic signaling pathway GO:0097191 3 0.021
cellular protein metabolic process GO:0044267 129 0.021
intracellular mrna localization GO:0008298 1 0.021
cell aging GO:0007569 2 0.021
regulation of metabolic process GO:0019222 359 0.021
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.021
cellular response to organic substance GO:0071310 105 0.021
aromatic compound biosynthetic process GO:0019438 217 0.021
positive regulation of developmental process GO:0051094 50 0.021
regulation of nucleotide catabolic process GO:0030811 2 0.020
negative regulation of metabolic process GO:0009892 86 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
multi organism process GO:0051704 134 0.019
regulation of cell shape GO:0008360 1 0.019
negative regulation of biosynthetic process GO:0009890 55 0.019
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
cellular amine metabolic process GO:0044106 2 0.019
response to oxygen containing compound GO:1901700 55 0.019
regulation of establishment of protein localization GO:0070201 4 0.018
modification dependent macromolecule catabolic process GO:0043632 3 0.018
translational initiation GO:0006413 3 0.018
positive regulation of cellular component biogenesis GO:0044089 3 0.018
cell proliferation GO:0008283 80 0.018
ion transport GO:0006811 114 0.018
muscle structure development GO:0061061 196 0.018
establishment of organelle localization GO:0051656 45 0.017
nucleic acid templated transcription GO:0097659 181 0.017
nucleobase containing small molecule metabolic process GO:0055086 32 0.017
regulation of cell death GO:0010941 103 0.017
cell substrate junction assembly GO:0007044 2 0.017
organelle localization GO:0051640 49 0.017
mononuclear cell proliferation GO:0032943 1 0.017
regulation of blood vessel size GO:0050880 2 0.017
regulation of nucleic acid templated transcription GO:1903506 213 0.017
regulation of protein catabolic process GO:0042176 1 0.017
response to stress GO:0006950 263 0.016
organic cyclic compound biosynthetic process GO:1901362 223 0.016
growth GO:0040007 174 0.016
protein import into nucleus GO:0006606 3 0.016
er nucleus signaling pathway GO:0006984 2 0.016
nucleobase containing compound metabolic process GO:0006139 274 0.016
multicellular organismal metabolic process GO:0044236 2 0.016
regulation of intracellular protein transport GO:0033157 3 0.016
rna metabolic process GO:0016070 219 0.015
regulation of rna biosynthetic process GO:2001141 213 0.015
gastrulation GO:0007369 208 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
transmembrane transport GO:0055085 120 0.015
regulation of primary metabolic process GO:0080090 311 0.015
death GO:0016265 121 0.015
cellular amino acid metabolic process GO:0006520 7 0.015
organelle organization GO:0006996 227 0.015
negative regulation of reproductive process GO:2000242 3 0.015
regulation of nucleoside metabolic process GO:0009118 2 0.015
cell cycle GO:0007049 93 0.014
regulation of biosynthetic process GO:0009889 250 0.014
regulation of macromolecule biosynthetic process GO:0010556 225 0.014
establishment of protein localization to organelle GO:0072594 4 0.014
small molecule metabolic process GO:0044281 77 0.014
regulation of macromolecule metabolic process GO:0060255 317 0.014
response to temperature stimulus GO:0009266 15 0.014
cellular modified amino acid metabolic process GO:0006575 3 0.014
organic acid metabolic process GO:0006082 31 0.014
multicellular organismal reproductive process GO:0048609 35 0.014
regulation of protein targeting GO:1903533 2 0.014
homeostatic process GO:0042592 142 0.013
regulation of cellular ketone metabolic process GO:0010565 7 0.013
positive regulation of catabolic process GO:0009896 4 0.013
outflow tract morphogenesis GO:0003151 1 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.013
rna localization GO:0006403 4 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.013
regulation of gtp catabolic process GO:0033124 2 0.013
cellular component biogenesis GO:0044085 178 0.013
heterocycle metabolic process GO:0046483 290 0.012
regulation of gtpase activity GO:0043087 2 0.012
neuron differentiation GO:0030182 353 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
negative regulation of multi organism process GO:0043901 3 0.012
cognition GO:0050890 1 0.012
behavior GO:0007610 74 0.012
mitotic cell cycle GO:0000278 64 0.012
autophagy GO:0006914 4 0.012
protein polymerization GO:0051258 4 0.012
response to abiotic stimulus GO:0009628 122 0.012
carbohydrate derivative metabolic process GO:1901135 61 0.012
response to organic substance GO:0010033 153 0.012
positive regulation of secretion GO:0051047 1 0.012
regulation of response to biotic stimulus GO:0002831 2 0.012
cellular component movement GO:0006928 335 0.012
regulation of apoptotic process GO:0042981 98 0.011
cation transport GO:0006812 81 0.011
regulation of protein transport GO:0051223 3 0.011
regulation of cell projection assembly GO:0060491 4 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
actin polymerization or depolymerization GO:0008154 2 0.011
hemopoiesis GO:0030097 183 0.011
muscle organ development GO:0007517 101 0.011
response to topologically incorrect protein GO:0035966 2 0.011
mitotic cytokinesis GO:0000281 3 0.011
sexual reproduction GO:0019953 36 0.011
programmed cell death GO:0012501 119 0.011
negative chemotaxis GO:0050919 1 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
single organism localization GO:1902578 225 0.011
cellular aromatic compound metabolic process GO:0006725 295 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
negative regulation of rna biosynthetic process GO:1902679 45 0.011
gene silencing by mirna GO:0035195 3 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
protein metabolic process GO:0019538 183 0.010
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.010
positive regulation of cell communication GO:0010647 56 0.010
nuclear import GO:0051170 3 0.010
cellular response to endogenous stimulus GO:0071495 68 0.010

ppib disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.036
immune system disease DOID:2914 0 0.016
aplastic anemia DOID:12449 0 0.016
congenital hypoplastic anemia DOID:1342 0 0.016
bone marrow disease DOID:4961 0 0.016
hematopoietic system disease DOID:74 0 0.016
anemia DOID:2355 0 0.016