Danio rerio

0 known processes

ppil2

peptidylprolyl isomerase (cyclophilin)-like 2

(Aliases: zgc:86735,si:dkeyp-86g2.1,MGC56616,zgc:56616)

ppil2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.179
regulation of meiotic cell cycle GO:0051445 1 0.089
meiotic nuclear division GO:0007126 4 0.078
establishment of localization GO:0051234 244 0.078
protein acetylation GO:0006473 2 0.071
response to carbohydrate GO:0009743 3 0.065
organelle organization GO:0006996 227 0.061
internal protein amino acid acetylation GO:0006475 2 0.057
peptidyl lysine acetylation GO:0018394 2 0.056
protein acylation GO:0043543 3 0.054
regulation of binding GO:0051098 3 0.053
meiotic cell cycle process GO:1903046 3 0.052
transport GO:0006810 220 0.050
locomotion GO:0040011 313 0.050
nuclear transport GO:0051169 4 0.046
cellular macromolecule biosynthetic process GO:0034645 224 0.044
response to monosaccharide GO:0034284 3 0.043
protein localization to nucleus GO:0034504 3 0.043
aging GO:0007568 2 0.042
protein localization to plasma membrane GO:0072659 1 0.041
Human
cellular carbohydrate metabolic process GO:0044262 4 0.041
protein targeting to nucleus GO:0044744 3 0.041
nucleocytoplasmic transport GO:0006913 4 0.040
single organism metabolic process GO:0044710 217 0.040
maintenance of location GO:0051235 4 0.038
response to hexose GO:0009746 3 0.038
cell cycle GO:0007049 93 0.038
cellular protein metabolic process GO:0044267 129 0.037
Human
regulation of metabolic process GO:0019222 359 0.037
regulation of cellular metabolic process GO:0031323 320 0.037
nuclear import GO:0051170 3 0.036
positive regulation of transport GO:0051050 2 0.036
transcription dna templated GO:0006351 181 0.035
positive regulation of cell cycle GO:0045787 3 0.035
protein import into nucleus GO:0006606 3 0.035
g1 s transition of mitotic cell cycle GO:0000082 1 0.035
negative regulation of biological process GO:0048519 304 0.035
cellular component movement GO:0006928 335 0.034
internal peptidyl lysine acetylation GO:0018393 2 0.034
cell cycle g1 s phase transition GO:0044843 1 0.033
embryo development ending in birth or egg hatching GO:0009792 271 0.033
regulation of protein transport GO:0051223 3 0.032
regulation of hormone secretion GO:0046883 2 0.032
protein metabolic process GO:0019538 183 0.031
Human
biosynthetic process GO:0009058 294 0.031
chromosome organization GO:0051276 31 0.029
localization of cell GO:0051674 244 0.029
organic substance biosynthetic process GO:1901576 289 0.028
energy reserve metabolic process GO:0006112 2 0.028
nucleic acid metabolic process GO:0090304 244 0.028
positive regulation of cellular process GO:0048522 201 0.028
negative regulation of nuclear division GO:0051784 3 0.027
neuron development GO:0048666 262 0.027
regulation of apoptotic process GO:0042981 98 0.026
response to glucose GO:0009749 3 0.026
rna localization GO:0006403 4 0.026
g2 m transition of mitotic cell cycle GO:0000086 4 0.026
regulation of response to stimulus GO:0048583 269 0.026
cell projection organization GO:0030030 284 0.026
regulation of macromolecule metabolic process GO:0060255 317 0.026
regulation of carbohydrate metabolic process GO:0006109 4 0.025
protein dephosphorylation GO:0006470 3 0.025
negative regulation of mitosis GO:0045839 3 0.025
regulation of nitrogen compound metabolic process GO:0051171 251 0.025
nucleic acid templated transcription GO:0097659 181 0.025
regulation of establishment of protein localization GO:0070201 4 0.025
establishment of protein localization to organelle GO:0072594 4 0.024
ncrna catabolic process GO:0034661 1 0.024
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.024
macromolecule modification GO:0043412 111 0.024
Human
mitotic dna damage checkpoint GO:0044773 4 0.024
phagocytosis GO:0006909 3 0.024
regulation of cytoplasmic transport GO:1903649 4 0.023
regulation of protein import into nucleus GO:0042306 2 0.023
organic cyclic compound metabolic process GO:1901360 301 0.023
cellular protein catabolic process GO:0044257 4 0.023
cellular biosynthetic process GO:0044249 286 0.023
protein import GO:0017038 3 0.023
regulation of primary metabolic process GO:0080090 311 0.023
establishment of rna localization GO:0051236 3 0.022
regulation of cell cycle process GO:0010564 20 0.022
regulation of cellular ketone metabolic process GO:0010565 7 0.022
cell motility GO:0048870 244 0.022
cell migration GO:0016477 237 0.022
proteasomal protein catabolic process GO:0010498 2 0.022
carbohydrate homeostasis GO:0033500 1 0.022
double strand break repair via homologous recombination GO:0000724 1 0.022
cellular protein modification process GO:0006464 100 0.022
Human
i kappab kinase nf kappab signaling GO:0007249 4 0.022
cell morphogenesis GO:0000902 289 0.022
regulation of chromosome segregation GO:0051983 1 0.021
lipid storage GO:0019915 1 0.021
regulation of cell death GO:0010941 103 0.021
apoptotic process GO:0006915 116 0.021
regulation of nucleocytoplasmic transport GO:0046822 2 0.021
single organism transport GO:0044765 206 0.021
regulation of synapse organization GO:0050807 3 0.021
cytokinesis GO:0000910 3 0.021
regulation of rna metabolic process GO:0051252 224 0.021
glucose homeostasis GO:0042593 1 0.020
protein modification process GO:0036211 100 0.020
Human
negative regulation of cellular process GO:0048523 283 0.020
regulation of intracellular protein transport GO:0033157 3 0.020
regulation of biosynthetic process GO:0009889 250 0.020
multicellular organism growth GO:0035264 4 0.019
cellular ketone metabolic process GO:0042180 11 0.019
digestive system development GO:0055123 289 0.019
mitochondrion organization GO:0007005 4 0.019
fertilization GO:0009566 3 0.019
central nervous system development GO:0007417 387 0.019
aromatic compound biosynthetic process GO:0019438 217 0.019
single fertilization GO:0007338 3 0.019
regulation of cellular biosynthetic process GO:0031326 245 0.019
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.019
programmed cell death GO:0012501 119 0.018
regulation of cell communication GO:0010646 232 0.018
modification dependent macromolecule catabolic process GO:0043632 3 0.018
response to nutrient GO:0007584 3 0.018
autophagy GO:0006914 4 0.018
small molecule metabolic process GO:0044281 77 0.018
regulation of protein targeting GO:1903533 2 0.018
cellular component morphogenesis GO:0032989 336 0.018
regulation of dna replication GO:0006275 3 0.018
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.018
multi organism process GO:0051704 134 0.018
regulation of protein ubiquitination GO:0031396 3 0.018
synaptic growth at neuromuscular junction GO:0051124 2 0.017
regulation of signal transduction GO:0009966 225 0.017
regulation of protein localization to nucleus GO:1900180 2 0.017
single organism nuclear import GO:1902593 3 0.017
meiotic chromosome segregation GO:0045132 3 0.017
regulation of mitotic cell cycle phase transition GO:1901990 8 0.017
neuron differentiation GO:0030182 353 0.017
protein stabilization GO:0050821 2 0.017
regulation of cell activation GO:0050865 1 0.017
chromosome organization involved in meiosis GO:0070192 1 0.017
gene expression GO:0010467 252 0.017
regulation of cell shape GO:0008360 1 0.016
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.016
oxidation reduction process GO:0055114 41 0.016
carbohydrate biosynthetic process GO:0016051 1 0.016
organic acid metabolic process GO:0006082 31 0.016
regulation of signaling GO:0023051 235 0.016
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.016
positive regulation of biological process GO:0048518 253 0.016
regionalization GO:0003002 274 0.016
modification dependent protein catabolic process GO:0019941 3 0.016
single organism organelle organization GO:1902589 199 0.016
heterocycle metabolic process GO:0046483 290 0.016
cognition GO:0050890 1 0.016
generation of neurons GO:0048699 385 0.015
protein polyubiquitination GO:0000209 4 0.015
Human
nucleobase containing compound transport GO:0015931 2 0.015
response to stress GO:0006950 263 0.015
extrinsic apoptotic signaling pathway GO:0097191 3 0.015
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.015
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
digestive tract development GO:0048565 265 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.015
mitotic cell cycle GO:0000278 64 0.015
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.015
mitotic g2 m transition checkpoint GO:0044818 3 0.015
hormone transport GO:0009914 2 0.015
oxoacid metabolic process GO:0043436 31 0.015
adult behavior GO:0030534 2 0.015
signal transduction GO:0007165 455 0.014
regulation of cellular amine metabolic process GO:0033238 0 0.014
secondary metabolic process GO:0019748 3 0.014
single organism biosynthetic process GO:0044711 71 0.014
spliceosomal snrnp assembly GO:0000387 2 0.014
nucleobase containing compound metabolic process GO:0006139 274 0.014
cellular amine metabolic process GO:0044106 2 0.014
cellular macromolecule metabolic process GO:0044260 391 0.014
Human
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.014
nuclear export GO:0051168 1 0.014
sensory organ development GO:0007423 393 0.014
mitotic dna integrity checkpoint GO:0044774 4 0.013
digestive tract morphogenesis GO:0048546 231 0.013
regulation of synapse assembly GO:0051963 3 0.013
cell cycle g2 m phase transition GO:0044839 4 0.013
cellular localization GO:0051641 97 0.013
Human
regulation of multicellular organism growth GO:0040014 4 0.013
rna transport GO:0050658 2 0.013
regulation of protein complex assembly GO:0043254 3 0.013
regulation of biological quality GO:0065008 263 0.013
tube morphogenesis GO:0035239 349 0.013
ubiquitin dependent protein catabolic process GO:0006511 3 0.013
g2 dna damage checkpoint GO:0031572 3 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
cell division GO:0051301 20 0.013
cell migration involved in gastrulation GO:0042074 79 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.013
regulation of protein catabolic process GO:0042176 1 0.013
recombinational repair GO:0000725 1 0.013
negative regulation of dna metabolic process GO:0051053 4 0.013
positive regulation of cellular catabolic process GO:0031331 3 0.012
dorsal ventral pattern formation GO:0009953 125 0.012
eye development GO:0001654 277 0.012
cellular nitrogen compound metabolic process GO:0034641 290 0.012
organic cyclic compound biosynthetic process GO:1901362 223 0.012
negative regulation of protein transport GO:0051224 3 0.012
ribosome assembly GO:0042255 1 0.012
interspecies interaction between organisms GO:0044419 4 0.012
negative regulation of response to dna damage stimulus GO:2001021 3 0.012
cellular amino acid metabolic process GO:0006520 7 0.012
rna biosynthetic process GO:0032774 181 0.012
cell projection morphogenesis GO:0048858 244 0.012
peptide transport GO:0015833 1 0.012
regulation of receptor activity GO:0010469 2 0.012
cellular response to external stimulus GO:0071496 2 0.012
single organism localization GO:1902578 225 0.012
Human
cell proliferation GO:0008283 80 0.012
mononuclear cell proliferation GO:0032943 1 0.012
multi organism cellular process GO:0044764 2 0.012
positive regulation of striated muscle tissue development GO:0045844 1 0.012
determination of bilateral symmetry GO:0009855 204 0.012
gtp metabolic process GO:0046039 4 0.012
regulation of translational initiation GO:0006446 1 0.012
positive regulation of catabolic process GO:0009896 4 0.012
protein modification by small protein removal GO:0070646 1 0.011
regulation of dna recombination GO:0000018 2 0.011
regulation of cellular protein catabolic process GO:1903362 1 0.011
spindle assembly GO:0051225 2 0.011
cell cycle process GO:0022402 53 0.011
phosphate containing compound metabolic process GO:0006796 108 0.011
rna 3 end processing GO:0031123 2 0.011
regulation of skeletal muscle tissue development GO:0048641 4 0.011
regulation of organ growth GO:0046620 3 0.011
regulation of carbohydrate biosynthetic process GO:0043255 1 0.011
brain development GO:0007420 293 0.011
amine metabolic process GO:0009308 2 0.011
positive regulation of cell activation GO:0050867 1 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
transcription from rna polymerase iii promoter GO:0006383 1 0.011
response to uv GO:0009411 3 0.011
morphogenesis of an epithelium GO:0002009 333 0.011
synaptic vesicle localization GO:0097479 1 0.011
meiosis i GO:0007127 1 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.011
response to drug GO:0042493 3 0.011
response to corticosteroid GO:0031960 1 0.011
negative regulation of intracellular transport GO:0032387 3 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
reactive nitrogen species metabolic process GO:2001057 0 0.011
specification of symmetry GO:0009799 204 0.011
cellular response to nutrient levels GO:0031669 2 0.011
organic substance transport GO:0071702 58 0.011
gastrulation GO:0007369 208 0.011
mrna transport GO:0051028 2 0.011
regulation of molecular function GO:0065009 70 0.011
regulation of dna damage response signal transduction by p53 class mediator GO:0043516 4 0.011
growth GO:0040007 174 0.011
cellular nitrogen compound biosynthetic process GO:0044271 218 0.011
nuclear envelope organization GO:0006998 2 0.011
regulation of programmed cell death GO:0043067 101 0.011
cell matrix adhesion GO:0007160 4 0.011
nitrogen compound metabolic process GO:0006807 319 0.011
gtp catabolic process GO:0006184 2 0.011
regulation of gene expression GO:0010468 265 0.010
positive regulation of dna metabolic process GO:0051054 1 0.010
regulation of autophagy GO:0010506 3 0.010
membrane invagination GO:0010324 1 0.010
cellular aromatic compound metabolic process GO:0006725 295 0.010
cell part morphogenesis GO:0032990 246 0.010
ameboidal type cell migration GO:0001667 143 0.010
response to ketone GO:1901654 1 0.010
cellular component disassembly GO:0022411 1 0.010
positive regulation of muscle tissue development GO:1901863 1 0.010
regulation of synaptic plasticity GO:0048167 1 0.010
cell cycle phase transition GO:0044770 9 0.010
hormone secretion GO:0046879 2 0.010

ppil2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.025
inherited metabolic disorder DOID:655 0 0.025
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.012
musculoskeletal system disease DOID:17 0 0.012