Danio rerio

11 known processes

ppm1g

protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform

(Aliases: cb167,wu:fe01e01,wu:fb37b10)

ppm1g biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
gene expression GO:0010467 252 0.708
regulation of primary metabolic process GO:0080090 311 0.695
larval development GO:0002164 2 0.646
cellular macromolecule biosynthetic process GO:0034645 224 0.528
organic cyclic compound biosynthetic process GO:1901362 223 0.497
cellular macromolecule metabolic process GO:0044260 391 0.495
regulation of cellular metabolic process GO:0031323 320 0.457
cellular nitrogen compound biosynthetic process GO:0044271 218 0.436
protein methylation GO:0006479 13 0.418
heterocycle metabolic process GO:0046483 290 0.411
organic substance biosynthetic process GO:1901576 289 0.403
nucleobase containing compound metabolic process GO:0006139 274 0.402
heterocycle biosynthetic process GO:0018130 215 0.401
rna biosynthetic process GO:0032774 181 0.400
signal transduction GO:0007165 455 0.380
biosynthetic process GO:0009058 294 0.367
regulation of gene expression GO:0010468 265 0.357
regulation of developmental process GO:0050793 247 0.352
protein modification process GO:0036211 100 0.347
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.343
negative regulation of metabolic process GO:0009892 86 0.334
rna transport GO:0050658 2 0.327
negative regulation of biological process GO:0048519 304 0.309
regulation of cell cycle GO:0051726 52 0.301
cellular protein metabolic process GO:0044267 129 0.300
regulation of metabolic process GO:0019222 359 0.294
single organism organelle organization GO:1902589 199 0.291
regulation of macromolecule biosynthetic process GO:0010556 225 0.290
cellular protein modification process GO:0006464 100 0.288
cellular biosynthetic process GO:0044249 286 0.265
histone methylation GO:0016571 13 0.260
organelle organization GO:0006996 227 0.256
regulation of biosynthetic process GO:0009889 250 0.255
negative regulation of cellular process GO:0048523 283 0.255
peptidyl lysine methylation GO:0018022 3 0.239
locomotion GO:0040011 313 0.238
negative regulation of gene expression GO:0010629 65 0.237
regulation of nucleic acid templated transcription GO:1903506 213 0.236
protein acetylation GO:0006473 2 0.236
nucleobase containing compound biosynthetic process GO:0034654 205 0.233
regulation of rna biosynthetic process GO:2001141 213 0.231
regulation of cellular biosynthetic process GO:0031326 245 0.226
reproduction GO:0000003 40 0.219
nuclear transport GO:0051169 4 0.211
transcription dna templated GO:0006351 181 0.211
nucleic acid metabolic process GO:0090304 244 0.211
nucleocytoplasmic transport GO:0006913 4 0.208
regulation of cellular protein metabolic process GO:0032268 52 0.203
cellular aromatic compound metabolic process GO:0006725 295 0.201
nucleic acid templated transcription GO:0097659 181 0.201
protein metabolic process GO:0019538 183 0.199
transport GO:0006810 220 0.196
cell cycle process GO:0022402 53 0.196
positive regulation of transport GO:0051050 2 0.178
developmental process involved in reproduction GO:0003006 27 0.165
histone modification GO:0016570 20 0.164
embryo development ending in birth or egg hatching GO:0009792 271 0.163
rna metabolic process GO:0016070 219 0.161
neuron development GO:0048666 262 0.161
aromatic compound biosynthetic process GO:0019438 217 0.159
regulation of transcription dna templated GO:0006355 213 0.141
nucleic acid transport GO:0050657 2 0.140
positive regulation of metabolic process GO:0009893 108 0.138
rna export from nucleus GO:0006405 1 0.136
cognition GO:0050890 1 0.131
macromolecule modification GO:0043412 111 0.129
single organism metabolic process GO:0044710 217 0.124
positive regulation of macromolecule metabolic process GO:0010604 93 0.122
methylation GO:0032259 22 0.121
negative regulation of cellular biosynthetic process GO:0031327 55 0.118
regulation of nucleocytoplasmic transport GO:0046822 2 0.117
response to stress GO:0006950 263 0.115
regulation of signal transduction GO:0009966 225 0.113
response to external stimulus GO:0009605 264 0.109
chordate embryonic development GO:0043009 271 0.109
gene silencing GO:0016458 4 0.108
internal protein amino acid acetylation GO:0006475 2 0.108
regulation of response to stimulus GO:0048583 269 0.108
nitrogen compound metabolic process GO:0006807 319 0.105
cellular response to dna damage stimulus GO:0006974 24 0.104
response to chemical GO:0042221 320 0.103
regulation of histone methylation GO:0031060 3 0.103
regulation of intracellular protein transport GO:0033157 3 0.101
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.101
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.098
segmentation GO:0035282 97 0.096
programmed cell death GO:0012501 119 0.095
establishment of localization GO:0051234 244 0.094
sensory perception GO:0007600 39 0.092
somite development GO:0061053 96 0.092
stem cell maintenance GO:0019827 4 0.091
cellular nitrogen compound metabolic process GO:0034641 290 0.090
regulation of cytoplasmic transport GO:1903649 4 0.090
regulation of protein transport GO:0051223 3 0.089
negative regulation of macromolecule metabolic process GO:0010605 76 0.088
cell surface receptor signaling pathway GO:0007166 325 0.086
protein targeting to nucleus GO:0044744 3 0.086
regulation of multicellular organism growth GO:0040014 4 0.086
establishment of protein localization to organelle GO:0072594 4 0.085
single fertilization GO:0007338 3 0.084
cellular carbohydrate metabolic process GO:0044262 4 0.084
nuclear import GO:0051170 3 0.083
cell cycle GO:0007049 93 0.082
muscle tissue development GO:0060537 110 0.080
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.079
pronuclear migration GO:0035046 1 0.078
cellular response to chemical stimulus GO:0070887 157 0.078
regulation of gene expression epigenetic GO:0040029 11 0.078
positive regulation of cellular process GO:0048522 201 0.077
mitotic dna integrity checkpoint GO:0044774 4 0.076
sexual reproduction GO:0019953 36 0.076
protein import GO:0017038 3 0.076
nuclear migration GO:0007097 3 0.076
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.076
embryonic organ morphogenesis GO:0048562 274 0.075
aging GO:0007568 2 0.075
multi organism process GO:0051704 134 0.075
organic cyclic compound metabolic process GO:1901360 301 0.074
negative regulation of rna metabolic process GO:0051253 48 0.073
macromolecule methylation GO:0043414 19 0.073
positive regulation of biological process GO:0048518 253 0.072
regulation of translational initiation GO:0006446 1 0.071
growth GO:0040007 174 0.071
regulation of nitrogen compound metabolic process GO:0051171 251 0.071
negative regulation of biosynthetic process GO:0009890 55 0.070
digestive system development GO:0055123 289 0.070
dna catabolic process GO:0006308 1 0.070
covalent chromatin modification GO:0016569 20 0.069
cell morphogenesis GO:0000902 289 0.068
regulation of carbohydrate metabolic process GO:0006109 4 0.068
negative regulation of signal transduction GO:0009968 94 0.067
mitotic cell cycle GO:0000278 64 0.067
regionalization GO:0003002 274 0.067
regulation of macromolecule metabolic process GO:0060255 317 0.065
internal peptidyl lysine acetylation GO:0018393 2 0.061
double strand break repair via nonhomologous end joining GO:0006303 1 0.058
central nervous system development GO:0007417 387 0.058
system process GO:0003008 185 0.057
response to organic substance GO:0010033 153 0.057
cellular component biogenesis GO:0044085 178 0.057
positive regulation of cellular metabolic process GO:0031325 94 0.057
protein import into nucleus GO:0006606 3 0.056
peptidyl lysine acetylation GO:0018394 2 0.056
multicellular organism growth GO:0035264 4 0.056
neurological system process GO:0050877 62 0.055
regulation of cell differentiation GO:0045595 142 0.052
regulation of establishment of protein localization GO:0070201 4 0.052
establishment of localization in cell GO:0051649 77 0.052
response to endogenous stimulus GO:0009719 83 0.052
regulation of cellular component organization GO:0051128 86 0.051
dna biosynthetic process GO:0071897 3 0.051
exocrine pancreas development GO:0031017 28 0.051
positive regulation of cellular protein metabolic process GO:0032270 22 0.051
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.048
response to abiotic stimulus GO:0009628 122 0.048
rna localization GO:0006403 4 0.047
regulation of protein metabolic process GO:0051246 56 0.047
regulation of circadian rhythm GO:0042752 4 0.046
positive regulation of chromatin modification GO:1903310 1 0.046
negative regulation of ras protein signal transduction GO:0046580 1 0.046
ras protein signal transduction GO:0007265 7 0.046
regulation of dna replication GO:0006275 3 0.046
non recombinational repair GO:0000726 2 0.046
chromatin modification GO:0016568 21 0.046
regulation of localization GO:0032879 104 0.045
heart morphogenesis GO:0003007 156 0.045
stem cell development GO:0048864 82 0.045
negative regulation of chromosome organization GO:2001251 1 0.045
positive regulation of cell cycle GO:0045787 3 0.044
regulation of cell communication GO:0010646 232 0.044
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.044
cellular component morphogenesis GO:0032989 336 0.043
transcription from rna polymerase ii promoter GO:0006366 80 0.043
negative regulation of cell differentiation GO:0045596 46 0.042
regulation of rna metabolic process GO:0051252 224 0.042
cell cycle g1 s phase transition GO:0044843 1 0.042
regulation of signaling GO:0023051 235 0.042
liver development GO:0001889 96 0.041
negative regulation of rna biosynthetic process GO:1902679 45 0.041
skeletal system development GO:0001501 181 0.040
generation of neurons GO:0048699 385 0.040
developmental growth GO:0048589 166 0.040
posttranscriptional gene silencing by rna GO:0035194 3 0.039
dna metabolic process GO:0006259 27 0.039
cellular localization GO:0051641 97 0.039
single organism biosynthetic process GO:0044711 71 0.038
translational initiation GO:0006413 3 0.038
regulation of chromatin organization GO:1902275 5 0.038
head development GO:0060322 303 0.038
small molecule metabolic process GO:0044281 77 0.037
immune system development GO:0002520 191 0.037
determination of bilateral symmetry GO:0009855 204 0.037
mitotic dna damage checkpoint GO:0044773 4 0.037
behavior GO:0007610 74 0.037
single organism nuclear import GO:1902593 3 0.036
protein alkylation GO:0008213 13 0.036
digestive tract development GO:0048565 265 0.036
regulation of mitotic cell cycle GO:0007346 25 0.036
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.036
macromolecular complex subunit organization GO:0043933 74 0.035
negative regulation of developmental process GO:0051093 65 0.035
protein localization GO:0008104 40 0.035
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.034
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 8 0.033
positive regulation of protein metabolic process GO:0051247 23 0.033
neuron projection development GO:0031175 180 0.033
mitotic cell cycle process GO:1903047 48 0.032
cardiac atrium morphogenesis GO:0003209 2 0.032
chromosome organization GO:0051276 31 0.032
organic substance transport GO:0071702 58 0.032
protein acylation GO:0043543 3 0.032
negative regulation of cell communication GO:0010648 96 0.031
macromolecule biosynthetic process GO:0009059 227 0.031
hematopoietic or lymphoid organ development GO:0048534 191 0.030
chromatin organization GO:0006325 22 0.030
negative regulation of cell cycle process GO:0010948 9 0.030
carboxylic acid metabolic process GO:0019752 22 0.030
cytokinesis GO:0000910 3 0.030
protein localization to nucleus GO:0034504 3 0.029
regulation of glial cell differentiation GO:0045685 4 0.029
positive regulation of translation GO:0045727 1 0.029
mitotic g2 dna damage checkpoint GO:0007095 3 0.029
negative regulation of nucleic acid templated transcription GO:1903507 45 0.029
morphogenesis of an epithelium GO:0002009 333 0.029
meiotic cell cycle process GO:1903046 3 0.028
cellular ketone metabolic process GO:0042180 11 0.028
intracellular transport GO:0046907 32 0.028
regulation of cell proliferation GO:0042127 37 0.028
regulation of protein ubiquitination GO:0031396 3 0.028
regulation of intracellular signal transduction GO:1902531 57 0.028
amine metabolic process GO:0009308 2 0.028
regulation of apoptotic process GO:0042981 98 0.027
maintenance of location GO:0051235 4 0.027
organic acid metabolic process GO:0006082 31 0.027
regeneration GO:0031099 91 0.027
negative regulation of transcription dna templated GO:0045892 45 0.027
muscle organ development GO:0007517 101 0.027
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.027
macromolecule localization GO:0033036 54 0.027
lipid storage GO:0019915 1 0.027
germ cell development GO:0007281 22 0.026
death GO:0016265 121 0.026
histone h3 k9 methylation GO:0051567 5 0.026
determination of heart left right asymmetry GO:0061371 117 0.026
nuclear export GO:0051168 1 0.026
cellular response to organic substance GO:0071310 105 0.026
embryonic organ development GO:0048568 381 0.025
epithelial cell differentiation GO:0030855 116 0.025
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.025
double strand break repair GO:0006302 3 0.025
positive regulation of carbohydrate metabolic process GO:0045913 1 0.024
muscle structure development GO:0061061 196 0.024
regulation of histone h3 k9 methylation GO:0051570 2 0.024
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.024
cell death GO:0008219 121 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.024
positive regulation of cellular amine metabolic process GO:0033240 0 0.024
embryonic heart tube morphogenesis GO:0003143 108 0.024
intracellular signal transduction GO:0035556 85 0.023
lateral inhibition GO:0046331 1 0.023
sex determination GO:0007530 1 0.023
regulation of protein localization to nucleus GO:1900180 2 0.023
negative regulation of apoptotic process GO:0043066 55 0.023
single organism reproductive process GO:0044702 40 0.023
cellular component movement GO:0006928 335 0.022
cell morphogenesis involved in differentiation GO:0000904 195 0.022
stem cell differentiation GO:0048863 117 0.022
embryonic skeletal joint morphogenesis GO:0060272 3 0.022
neuron differentiation GO:0030182 353 0.022
skin development GO:0043588 54 0.022
regulation of multicellular organismal process GO:0051239 277 0.021
regulation of programmed cell death GO:0043067 101 0.021
regulation of protein import into nucleus GO:0042306 2 0.021
histone h4 k20 methylation GO:0034770 2 0.021
negative regulation of cellular metabolic process GO:0031324 77 0.021
cell projection organization GO:0030030 284 0.021
cellular amino acid metabolic process GO:0006520 7 0.021
single organism intracellular transport GO:1902582 25 0.021
oogenesis GO:0048477 14 0.021
axonogenesis GO:0007409 152 0.020
heart development GO:0007507 313 0.020
b cell mediated immunity GO:0019724 3 0.020
fertilization GO:0009566 3 0.020
cell division GO:0051301 20 0.020
b cell activation GO:0042113 2 0.020
regulation of neural precursor cell proliferation GO:2000177 3 0.020
cell proliferation GO:0008283 80 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
oxoacid metabolic process GO:0043436 31 0.019
macromolecular complex assembly GO:0065003 35 0.019
single organism localization GO:1902578 225 0.019
regulation of gene silencing GO:0060968 1 0.019
chemotaxis GO:0006935 104 0.019
meiotic nuclear division GO:0007126 4 0.019
negative regulation of programmed cell death GO:0043069 58 0.019
negative regulation of dna replication GO:0008156 2 0.019
g2 m transition of mitotic cell cycle GO:0000086 4 0.019
regulation of organelle organization GO:0033043 29 0.019
gene silencing by rna GO:0031047 4 0.019
organonitrogen compound metabolic process GO:1901564 74 0.018
protein deacylation GO:0035601 3 0.018
positive regulation of cellular biosynthetic process GO:0031328 68 0.018
striated muscle tissue development GO:0014706 110 0.018
positive regulation of signaling GO:0023056 56 0.018
axon development GO:0061564 166 0.018
g1 s transition of mitotic cell cycle GO:0000082 1 0.018
meiosis i GO:0007127 1 0.018
tube morphogenesis GO:0035239 349 0.018
microtubule based process GO:0007017 60 0.018
cell part morphogenesis GO:0032990 246 0.018
g2 dna damage checkpoint GO:0031572 3 0.017
nucleoside phosphate metabolic process GO:0006753 28 0.017
reproductive process GO:0022414 40 0.017
positive regulation of gliogenesis GO:0014015 2 0.017
posttranscriptional regulation of gene expression GO:0010608 14 0.017
regulation of phosphate metabolic process GO:0019220 43 0.017
immune system process GO:0002376 241 0.017
response to wounding GO:0009611 116 0.016
negative regulation of histone modification GO:0031057 1 0.016
compound eye development GO:0048749 2 0.016
posttranscriptional gene silencing GO:0016441 3 0.016
specification of symmetry GO:0009799 204 0.016
regulation of carbohydrate biosynthetic process GO:0043255 1 0.016
production of molecular mediator of immune response GO:0002440 2 0.016
embryonic digestive tract morphogenesis GO:0048557 3 0.016
regulation of phosphorus metabolic process GO:0051174 43 0.016
regulation of protein targeting GO:1903533 2 0.016
brain development GO:0007420 293 0.016
histone h3 k9 modification GO:0061647 5 0.016
cell fate specification GO:0001708 68 0.016
embryonic heart tube development GO:0035050 133 0.015
establishment of rna localization GO:0051236 3 0.015
phosphorus metabolic process GO:0006793 109 0.015
regulation of myotube differentiation GO:0010830 2 0.015
nucleobase containing small molecule metabolic process GO:0055086 32 0.015
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.015
negative regulation of response to stimulus GO:0048585 104 0.015
cell motility GO:0048870 244 0.015
cellular component assembly GO:0022607 170 0.015
mitotic cell cycle embryonic GO:0045448 2 0.014
response to uv GO:0009411 3 0.014
positive regulation of catalytic activity GO:0043085 25 0.014
regulation of hydrolase activity GO:0051336 28 0.014
convergent extension GO:0060026 118 0.014
cytoskeleton organization GO:0007010 96 0.014
pancreas development GO:0031016 84 0.014
cell cycle arrest GO:0007050 1 0.014
regulation of protein modification process GO:0031399 29 0.014
histone deacetylation GO:0016575 2 0.014
positive regulation of histone modification GO:0031058 1 0.014
regulation of transport GO:0051049 45 0.014
positive regulation of chromosome organization GO:2001252 1 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
negative regulation of cell cycle GO:0045786 14 0.014
positive regulation of molecular function GO:0044093 33 0.014
regulation of molecular function GO:0065009 70 0.014
hemopoiesis GO:0030097 183 0.014
palate development GO:0060021 8 0.013
pigmentation GO:0043473 85 0.013
cell aging GO:0007569 2 0.013
regulation of ion transmembrane transporter activity GO:0032412 2 0.013
skeletal muscle organ development GO:0060538 78 0.013
anterior posterior pattern specification GO:0009952 152 0.013
cellular amine metabolic process GO:0044106 2 0.013
blood vessel development GO:0001568 246 0.013
dna methylation or demethylation GO:0044728 8 0.013
dna modification GO:0006304 8 0.013
hepaticobiliary system development GO:0061008 98 0.013
cartilage development GO:0051216 96 0.013
regulation of cell activation GO:0050865 1 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 5 0.013
tissue regeneration GO:0042246 74 0.013
mrna transport GO:0051028 2 0.013
regulation of response to stress GO:0080134 36 0.013
epithelial tube morphogenesis GO:0060562 148 0.013
negative regulation of dna metabolic process GO:0051053 4 0.013
positive regulation of glial cell differentiation GO:0045687 1 0.013
canonical wnt signaling pathway GO:0060070 48 0.013
neuron projection morphogenesis GO:0048812 161 0.013
positive regulation of dna metabolic process GO:0051054 1 0.013
cellular protein localization GO:0034613 20 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.012
synaptic growth at neuromuscular junction GO:0051124 2 0.012
regulation of catalytic activity GO:0050790 55 0.012
embryonic pattern specification GO:0009880 44 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
response to drug GO:0042493 3 0.012
sensory perception of light stimulus GO:0050953 19 0.012
peptidyl amino acid modification GO:0018193 16 0.012
cellular response to dsrna GO:0071359 1 0.012
positive regulation of biosynthetic process GO:0009891 68 0.012
centrosome organization GO:0051297 1 0.012
regulation of cellular amine metabolic process GO:0033238 0 0.012
carbohydrate biosynthetic process GO:0016051 1 0.012
immunoglobulin mediated immune response GO:0016064 3 0.012
regulation of ion transmembrane transport GO:0034765 18 0.012
single organism cellular localization GO:1902580 46 0.012
ear development GO:0043583 127 0.012
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
response to amino acid GO:0043200 2 0.011
regulation of meiotic cell cycle GO:0051445 1 0.011
positive regulation of cellular catabolic process GO:0031331 3 0.011
histone h3 k4 methylation GO:0051568 2 0.011
female gamete generation GO:0007292 14 0.011
fin regeneration GO:0031101 51 0.011
photoreceptor cell development GO:0042461 40 0.011
response to lipid GO:0033993 60 0.011
skeletal muscle tissue development GO:0007519 67 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
negative regulation of histone methylation GO:0031061 1 0.011
regulation of cell cycle process GO:0010564 20 0.011
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.011
regulation of endopeptidase activity GO:0052548 23 0.011
cellular response to endogenous stimulus GO:0071495 68 0.011
positive regulation of response to stimulus GO:0048584 80 0.011
dorsal ventral pattern formation GO:0009953 125 0.011
positive regulation of signal transduction GO:0009967 56 0.011
negative regulation of cell death GO:0060548 60 0.011
negative regulation of dna templated transcription elongation GO:0032785 1 0.011
cellular component disassembly GO:0022411 1 0.011
single organism transport GO:0044765 206 0.010
regulation of response to dna damage stimulus GO:2001020 5 0.010
positive regulation of cell activation GO:0050867 1 0.010
macromolecule deacylation GO:0098732 3 0.010
mitotic nuclear division GO:0007067 18 0.010
response to light stimulus GO:0009416 46 0.010
connective tissue development GO:0061448 99 0.010
cell projection morphogenesis GO:0048858 244 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.010
response to external biotic stimulus GO:0043207 97 0.010
regulation of cysteine type endopeptidase activity GO:2000116 21 0.010

ppm1g disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.012
neuromuscular disease DOID:440 0 0.010
charcot marie tooth disease DOID:10595 0 0.010
neuropathy DOID:870 0 0.010