Danio rerio

0 known processes

ppox

protoporphyrinogen oxidase

(Aliases: MGC123252,zgc:123252)

ppox biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
hematopoietic or lymphoid organ development GO:0048534 191 0.696
erythrocyte maturation GO:0043249 8 0.469
hemopoiesis GO:0030097 183 0.438
erythrocyte differentiation GO:0030218 54 0.418
myeloid cell differentiation GO:0030099 86 0.341
cofactor biosynthetic process GO:0051188 10 0.307
embryonic hemopoiesis GO:0035162 53 0.241
immune system process GO:0002376 241 0.219
tetrapyrrole biosynthetic process GO:0033014 8 0.219
porphyrin containing compound metabolic process GO:0006778 10 0.215
primitive hemopoiesis GO:0060215 27 0.210
immune system development GO:0002520 191 0.201
cellular macromolecule biosynthetic process GO:0034645 224 0.183
transition metal ion transport GO:0000041 6 0.167
nitrogen compound metabolic process GO:0006807 319 0.166
heme metabolic process GO:0042168 9 0.160
cellular aromatic compound metabolic process GO:0006725 295 0.151
tetrapyrrole metabolic process GO:0033013 10 0.151
regulation of signal transduction GO:0009966 225 0.146
hemoglobin biosynthetic process GO:0042541 8 0.142
iron ion transport GO:0006826 4 0.134
porphyrin containing compound biosynthetic process GO:0006779 8 0.131
signal transduction GO:0007165 455 0.128
embryonic organ development GO:0048568 381 0.115
larval development GO:0002164 2 0.108
regulation of binding GO:0051098 3 0.099
nucleic acid metabolic process GO:0090304 244 0.098
regulation of metabolic process GO:0019222 359 0.094
ion transport GO:0006811 114 0.094
heterocycle metabolic process GO:0046483 290 0.093
organic cyclic compound metabolic process GO:1901360 301 0.086
myeloid cell homeostasis GO:0002262 56 0.086
single organism transport GO:0044765 206 0.084
gene expression GO:0010467 252 0.082
regulation of response to stimulus GO:0048583 269 0.082
antimicrobial humoral response GO:0019730 2 0.081
regulation of biological quality GO:0065008 263 0.079
organic substance biosynthetic process GO:1901576 289 0.076
cell surface receptor signaling pathway GO:0007166 325 0.075
erythrocyte homeostasis GO:0034101 55 0.075
regulation of cell communication GO:0010646 232 0.075
biosynthetic process GO:0009058 294 0.070
metal ion transport GO:0030001 58 0.069
central nervous system development GO:0007417 387 0.069
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.067
primitive erythrocyte differentiation GO:0060319 5 0.065
aromatic compound biosynthetic process GO:0019438 217 0.064
erythrocyte development GO:0048821 24 0.063
heme biosynthetic process GO:0006783 8 0.062
cellular nitrogen compound metabolic process GO:0034641 290 0.061
definitive hemopoiesis GO:0060216 18 0.059
localization of cell GO:0051674 244 0.059
regulation of gene expression GO:0010468 265 0.058
negative regulation of biological process GO:0048519 304 0.057
cellular nitrogen compound biosynthetic process GO:0044271 218 0.054
cellular biosynthetic process GO:0044249 286 0.052
response to external stimulus GO:0009605 264 0.051
cellular response to lipopolysaccharide GO:0071222 3 0.050
centrosome cycle GO:0007098 1 0.050
single organism metabolic process GO:0044710 217 0.050
osteoclast differentiation GO:0030316 1 0.048
myeloid leukocyte differentiation GO:0002573 15 0.048
morphogenesis of an epithelium GO:0002009 333 0.048
regulation of protein binding GO:0043393 3 0.047
protein metabolic process GO:0019538 183 0.047
toll like receptor signaling pathway GO:0002224 4 0.047
cell morphogenesis GO:0000902 289 0.047
response to superoxide GO:0000303 2 0.046
centrosome organization GO:0051297 1 0.046
organonitrogen compound metabolic process GO:1901564 74 0.045
skeletal system morphogenesis GO:0048705 102 0.045
organonitrogen compound biosynthetic process GO:1901566 47 0.045
macromolecule biosynthetic process GO:0009059 227 0.045
cell projection organization GO:0030030 284 0.044
centrosome duplication GO:0051298 1 0.044
ion transmembrane transport GO:0034220 91 0.043
regulation of cellular metabolic process GO:0031323 320 0.043
locomotion GO:0040011 313 0.043
regulation of establishment of protein localization GO:0070201 4 0.043
homeostasis of number of cells GO:0048872 62 0.042
intracellular signal transduction GO:0035556 85 0.042
maintenance of location GO:0051235 4 0.042
segmentation GO:0035282 97 0.042
rna metabolic process GO:0016070 219 0.041
regulation of cell differentiation GO:0045595 142 0.040
single organism localization GO:1902578 225 0.040
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.039
cellular component biogenesis GO:0044085 178 0.038
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.038
lipid storage GO:0019915 1 0.037
regulation of signaling GO:0023051 235 0.037
response to biotic stimulus GO:0009607 97 0.037
organic cyclic compound biosynthetic process GO:1901362 223 0.037
cellular amide metabolic process GO:0043603 4 0.037
regulation of protein transport GO:0051223 3 0.036
taxis GO:0042330 109 0.036
heterocycle biosynthetic process GO:0018130 215 0.036
regulation of cytokine production GO:0001817 3 0.035
myeloid cell development GO:0061515 32 0.035
transmembrane transport GO:0055085 120 0.035
cell migration GO:0016477 237 0.033
developmental maturation GO:0021700 34 0.033
homeostatic process GO:0042592 142 0.032
cation transport GO:0006812 81 0.031
regulation of multicellular organismal development GO:2000026 223 0.031
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.031
regulation of synapse assembly GO:0051963 3 0.031
regulation of multicellular organismal process GO:0051239 277 0.031
cell projection morphogenesis GO:0048858 244 0.031
tyrosine phosphorylation of stat protein GO:0007260 1 0.030
positive regulation of cytokine production GO:0001819 2 0.030
regulation of macromolecule metabolic process GO:0060255 317 0.029
phagocytosis GO:0006909 3 0.029
synaptic growth at neuromuscular junction GO:0051124 2 0.029
cytokinesis GO:0000910 3 0.029
pole plasm assembly GO:0007315 4 0.029
response to stress GO:0006950 263 0.029
outflow tract morphogenesis GO:0003151 1 0.029
superoxide metabolic process GO:0006801 2 0.029
regulation of stem cell differentiation GO:2000736 4 0.029
mononuclear cell proliferation GO:0032943 1 0.028
cellular component movement GO:0006928 335 0.028
cellular response to molecule of bacterial origin GO:0071219 3 0.028
response to external biotic stimulus GO:0043207 97 0.028
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.028
regulation of synapse organization GO:0050807 3 0.028
skeletal system development GO:0001501 181 0.027
tissue remodeling GO:0048771 4 0.027
heart morphogenesis GO:0003007 156 0.027
enzyme linked receptor protein signaling pathway GO:0007167 106 0.026
protein localization to nucleus GO:0034504 3 0.026
negative regulation of cytokine production GO:0001818 1 0.026
generation of neurons GO:0048699 385 0.026
regulation of erythrocyte differentiation GO:0045646 2 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.025
central nervous system neuron differentiation GO:0021953 74 0.025
regulation of protein targeting GO:1903533 2 0.025
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.025
compound eye development GO:0048749 2 0.025
cardiac atrium morphogenesis GO:0003209 2 0.025
production of molecular mediator of immune response GO:0002440 2 0.025
hepaticobiliary system development GO:0061008 98 0.025
response to chemical GO:0042221 320 0.024
anterior posterior pattern specification GO:0009952 152 0.024
brain development GO:0007420 293 0.024
cofactor metabolic process GO:0051186 15 0.024
pancreas development GO:0031016 84 0.024
negative regulation of multicellular organismal process GO:0051241 69 0.024
organic acid metabolic process GO:0006082 31 0.024
embryonic skeletal system morphogenesis GO:0048704 93 0.024
negative regulation of cellular process GO:0048523 283 0.024
response to other organism GO:0051707 97 0.023
cellular transition metal ion homeostasis GO:0046916 3 0.023
regulation of transcription dna templated GO:0006355 213 0.023
organic substance transport GO:0071702 58 0.023
cellular response to chemical stimulus GO:0070887 157 0.023
regulation of cell shape GO:0008360 1 0.023
inorganic ion transmembrane transport GO:0098660 57 0.023
tube morphogenesis GO:0035239 349 0.022
cellular response to superoxide GO:0071451 2 0.022
regulation of immune system process GO:0002682 34 0.022
ovulation cycle GO:0042698 2 0.021
cytoplasm organization GO:0007028 4 0.021
microtubule organizing center organization GO:0031023 1 0.021
establishment of localization GO:0051234 244 0.021
cell morphogenesis involved in differentiation GO:0000904 195 0.021
exocytosis GO:0006887 1 0.021
hindbrain development GO:0030902 91 0.020
regeneration GO:0031099 91 0.020
ribosomal small subunit biogenesis GO:0042274 2 0.020
multi organism process GO:0051704 134 0.020
aging GO:0007568 2 0.020
positive regulation of gene expression GO:0010628 71 0.020
wnt signaling pathway GO:0016055 80 0.020
leukocyte differentiation GO:0002521 25 0.020
iron ion homeostasis GO:0055072 4 0.020
removal of superoxide radicals GO:0019430 2 0.020
regulation of dendrite development GO:0050773 3 0.020
transport GO:0006810 220 0.020
cellular component morphogenesis GO:0032989 336 0.020
multicellular organismal homeostasis GO:0048871 29 0.019
regulation of intracellular protein transport GO:0033157 3 0.019
mitochondrion organization GO:0007005 4 0.019
megakaryocyte differentiation GO:0030219 1 0.019
head development GO:0060322 303 0.019
cognition GO:0050890 1 0.019
cation transmembrane transport GO:0098655 65 0.018
mesoderm development GO:0007498 88 0.018
rna localization GO:0006403 4 0.018
wound healing GO:0042060 90 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.018
erk1 and erk2 cascade GO:0070371 4 0.018
positive regulation of myeloid cell differentiation GO:0045639 2 0.018
modification dependent macromolecule catabolic process GO:0043632 3 0.018
peptide metabolic process GO:0006518 1 0.018
positive regulation of map kinase activity GO:0043406 3 0.018
cellular amine metabolic process GO:0044106 2 0.018
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.018
developmental growth GO:0048589 166 0.018
regulation of bone remodeling GO:0046850 2 0.018
bone remodeling GO:0046849 2 0.018
g2 m transition of mitotic cell cycle GO:0000086 4 0.017
i kappab kinase nf kappab signaling GO:0007249 4 0.017
regulation of histone methylation GO:0031060 3 0.017
cell part morphogenesis GO:0032990 246 0.017
intestinal absorption GO:0050892 2 0.017
cellular macromolecule metabolic process GO:0044260 391 0.017
negative regulation of gene expression GO:0010629 65 0.017
response to bacterium GO:0009617 58 0.017
endosomal transport GO:0016197 2 0.017
astrocyte differentiation GO:0048708 1 0.017
platelet formation GO:0030220 1 0.017
endosome organization GO:0007032 2 0.017
hormone transport GO:0009914 2 0.017
amine metabolic process GO:0009308 2 0.017
cell maturation GO:0048469 23 0.017
positive regulation of cell cycle GO:0045787 3 0.016
cellular response to external stimulus GO:0071496 2 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
cellular response to stress GO:0033554 62 0.016
peptide transport GO:0015833 1 0.016
response to oxygen radical GO:0000305 2 0.016
response to drug GO:0042493 3 0.016
nuclear import GO:0051170 3 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.016
single organism nuclear import GO:1902593 3 0.016
negative regulation of stem cell differentiation GO:2000737 2 0.016
embryonic organ morphogenesis GO:0048562 274 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
sensory organ development GO:0007423 393 0.016
axonogenesis GO:0007409 152 0.016
neuron development GO:0048666 262 0.015
cellular response to extracellular stimulus GO:0031668 2 0.015
lymphocyte proliferation GO:0046651 1 0.015
negative regulation of cell communication GO:0010648 96 0.015
cellular response to biotic stimulus GO:0071216 3 0.015
chordate embryonic development GO:0043009 271 0.015
signal transduction in absence of ligand GO:0038034 1 0.015
transcription from rna polymerase ii promoter GO:0006366 80 0.015
negative regulation of myeloid cell differentiation GO:0045638 1 0.015
axon development GO:0061564 166 0.015
positive regulation of biological process GO:0048518 253 0.015
regulation of rna metabolic process GO:0051252 224 0.015
leukocyte proliferation GO:0070661 1 0.015
negative regulation of cell death GO:0060548 60 0.015
toxin transport GO:1901998 2 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.015
regulation of developmental process GO:0050793 247 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
mitochondrial transport GO:0006839 2 0.015
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.015
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.015
positive regulation of jak stat cascade GO:0046427 2 0.015
negative regulation of developmental process GO:0051093 65 0.014
internal peptidyl lysine acetylation GO:0018393 2 0.014
oocyte anterior posterior axis specification GO:0007314 4 0.014
negative regulation of nuclear division GO:0051784 3 0.014
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.014
multicellular organism growth GO:0035264 4 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.014
protein targeting to nucleus GO:0044744 3 0.014
regulation of bone mineralization GO:0030500 2 0.014
inorganic cation transmembrane transport GO:0098662 50 0.014
convergent extension GO:0060026 118 0.014
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.014
carbohydrate homeostasis GO:0033500 1 0.014
sleep GO:0030431 1 0.013
regulation of tissue remodeling GO:0034103 2 0.013
intracellular mrna localization GO:0008298 1 0.013
ion homeostasis GO:0050801 41 0.013
system process GO:0003008 185 0.013
cellular response to oxygen radical GO:0071450 2 0.013
embryo development ending in birth or egg hatching GO:0009792 271 0.013
protein secretion GO:0009306 1 0.013
positive regulation of protein complex assembly GO:0031334 2 0.013
cellular protein catabolic process GO:0044257 4 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
monocyte differentiation GO:0030224 2 0.013
gtp metabolic process GO:0046039 4 0.013
stem cell proliferation GO:0072089 4 0.013
spindle assembly involved in mitosis GO:0090307 1 0.013
negative regulation of catabolic process GO:0009895 3 0.013
muscle cell differentiation GO:0042692 139 0.013
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.013
nucleobase containing compound biosynthetic process GO:0034654 205 0.013
atp catabolic process GO:0006200 4 0.013
nucleobase containing compound metabolic process GO:0006139 274 0.013
positive regulation of cell division GO:0051781 2 0.013
negative regulation of protein transport GO:0051224 3 0.013
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 1 0.013
nucleobase containing compound transport GO:0015931 2 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
cellular response to reactive oxygen species GO:0034614 2 0.013
sexual reproduction GO:0019953 36 0.013
b cell differentiation GO:0030183 1 0.013
startle response GO:0001964 4 0.013
regulation of protein localization to nucleus GO:1900180 2 0.013
endocrine process GO:0050886 2 0.013
primary neural tube formation GO:0014020 1 0.013
regulation of nitrogen compound metabolic process GO:0051171 251 0.013
growth GO:0040007 174 0.013
stem cell maintenance GO:0019827 4 0.013
membrane fusion GO:0061025 2 0.012
muscle structure development GO:0061061 196 0.012
renal filtration GO:0097205 10 0.012
transcription dna templated GO:0006351 181 0.012
glial cell differentiation GO:0010001 42 0.012
kidney development GO:0001822 92 0.012
regulation of jak stat cascade GO:0046425 3 0.012
multicellular organismal signaling GO:0035637 22 0.012
histone h3 k4 methylation GO:0051568 2 0.012
cellular iron ion homeostasis GO:0006879 3 0.012
protein import GO:0017038 3 0.012
cardiac atrium development GO:0003230 4 0.012
regulation of protein import into nucleus GO:0042306 2 0.012
glucose homeostasis GO:0042593 1 0.012
ph reduction GO:0045851 1 0.012
macromolecular complex subunit organization GO:0043933 74 0.012
extrinsic apoptotic signaling pathway GO:0097191 3 0.012
spermatid differentiation GO:0048515 2 0.012
interspecies interaction between organisms GO:0044419 4 0.012
actin filament polymerization GO:0030041 2 0.012
neuron fate determination GO:0048664 2 0.012
tissue regeneration GO:0042246 74 0.012
positive regulation of transport GO:0051050 2 0.012
regulation of production of molecular mediator of immune response GO:0002700 1 0.012
protein stabilization GO:0050821 2 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.012
heart valve formation GO:0003188 4 0.012
regulation of cardiac muscle tissue development GO:0055024 1 0.012
neurotransmitter transport GO:0006836 2 0.012
phagocytosis engulfment GO:0006911 1 0.011
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.011
granulocyte differentiation GO:0030851 8 0.011
regulation of biosynthetic process GO:0009889 250 0.011
regulation of cellular ketone metabolic process GO:0010565 7 0.011
microtubule based process GO:0007017 60 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
somatic muscle development GO:0007525 4 0.011
calcium mediated signaling GO:0019722 2 0.011
phosphorylation GO:0016310 69 0.011
single fertilization GO:0007338 3 0.011
regulation of cytokine biosynthetic process GO:0042035 1 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
regulation of multicellular organism growth GO:0040014 4 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
regulation of neurotransmitter transport GO:0051588 1 0.011
cell proliferation GO:0008283 80 0.011
response to uv GO:0009411 3 0.011
endocrine hormone secretion GO:0060986 2 0.011
epithelial cell differentiation GO:0030855 116 0.011
cation homeostasis GO:0055080 33 0.011
iron ion transmembrane transport GO:0034755 3 0.011
regulation of gene expression epigenetic GO:0040029 11 0.011
positive regulation of catabolic process GO:0009896 4 0.011
transmission of nerve impulse GO:0019226 19 0.011
maternal determination of anterior posterior axis embryo GO:0008358 4 0.011
negative regulation of secretion by cell GO:1903531 2 0.011
ventricular cardiac myofibril assembly GO:0055005 4 0.011
inner ear development GO:0048839 126 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.011
negative regulation of mitosis GO:0045839 3 0.010
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 1 0.010
regulation of dendrite morphogenesis GO:0048814 3 0.010
nucleic acid transport GO:0050657 2 0.010
determination of left right asymmetry in nervous system GO:0035545 4 0.010
urogenital system development GO:0001655 97 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.010
cytokine metabolic process GO:0042107 1 0.010
nephron tubule morphogenesis GO:0072078 1 0.010
oxoacid metabolic process GO:0043436 31 0.010
cellular ketone metabolic process GO:0042180 11 0.010
positive regulation of cellular component biogenesis GO:0044089 3 0.010
immune response GO:0006955 28 0.010
neuron neuron synaptic transmission GO:0007270 1 0.010
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.010
leukocyte homeostasis GO:0001776 2 0.010
epithelial cell development GO:0002064 42 0.010
epithelial tube morphogenesis GO:0060562 148 0.010
sensory organ morphogenesis GO:0090596 200 0.010
regulation of protein catabolic process GO:0042176 1 0.010

ppox disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041
immune system disease DOID:2914 0 0.020
hematopoietic system disease DOID:74 0 0.020
bone marrow disease DOID:4961 0 0.019
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
disease of metabolism DOID:0014667 0 0.014
organ system cancer DOID:0050686 0 0.014
inherited metabolic disorder DOID:655 0 0.013
sensory system disease DOID:0050155 0 0.010
nervous system disease DOID:863 0 0.010