Danio rerio

0 known processes

ppp6r2

protein phosphatase 6, regulatory subunit 2

(Aliases: saps2,MGC136621,zgc:136621,fd18a05,si:dkey-159a18.3,wu:fd18a05)

ppp6r2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
larval development GO:0002164 2 0.111
cellular nitrogen compound metabolic process GO:0034641 290 0.088
cellular macromolecule metabolic process GO:0044260 391 0.088
neuron development GO:0048666 262 0.082
hemopoiesis GO:0030097 183 0.081
aging GO:0007568 2 0.081
nuclear transport GO:0051169 4 0.079
negative regulation of protein phosphorylation GO:0001933 4 0.077
regulation of biological quality GO:0065008 263 0.069
regulation of nucleocytoplasmic transport GO:0046822 2 0.069
cellular protein metabolic process GO:0044267 129 0.065
medulla oblongata development GO:0021550 4 0.061
organelle organization GO:0006996 227 0.060
establishment of protein localization to organelle GO:0072594 4 0.059
nucleocytoplasmic transport GO:0006913 4 0.057
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.055
single organism organelle organization GO:1902589 199 0.055
maintenance of location GO:0051235 4 0.053
lipid storage GO:0019915 1 0.053
protein heterooligomerization GO:0051291 1 0.052
cellular component morphogenesis GO:0032989 336 0.051
positive regulation of cell cycle GO:0045787 3 0.051
protein metabolic process GO:0019538 183 0.050
generation of neurons GO:0048699 385 0.045
centrosome cycle GO:0007098 1 0.045
ubiquitin dependent protein catabolic process GO:0006511 3 0.044
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.043
regulation of cell shape GO:0008360 1 0.043
vasculature development GO:0001944 278 0.042
regulation of glucose import GO:0046324 1 0.042
modification dependent macromolecule catabolic process GO:0043632 3 0.042
modification dependent protein catabolic process GO:0019941 3 0.040
purine nucleoside monophosphate catabolic process GO:0009128 4 0.039
nucleobase containing compound metabolic process GO:0006139 274 0.039
heterocycle metabolic process GO:0046483 290 0.039
cell morphogenesis involved in differentiation GO:0000904 195 0.039
positive regulation of notch signaling pathway GO:0045747 3 0.039
regulation of developmental process GO:0050793 247 0.037
cellular component assembly GO:0022607 170 0.037
establishment of localization GO:0051234 244 0.037
multi organism process GO:0051704 134 0.037
organic cyclic compound metabolic process GO:1901360 301 0.036
extrinsic apoptotic signaling pathway GO:0097191 3 0.036
neuron differentiation GO:0030182 353 0.036
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.036
cellular lipid catabolic process GO:0044242 3 0.035
positive regulation of glucose import GO:0046326 1 0.035
nucleic acid metabolic process GO:0090304 244 0.034
cellular protein catabolic process GO:0044257 4 0.034
pyruvate metabolic process GO:0006090 1 0.034
negative regulation of response to stimulus GO:0048585 104 0.033
embryo development ending in birth or egg hatching GO:0009792 271 0.033
mitochondrion organization GO:0007005 4 0.033
regulation of glucose transport GO:0010827 1 0.033
single organism reproductive process GO:0044702 40 0.033
cell cycle g1 s phase transition GO:0044843 1 0.033
positive regulation of transport GO:0051050 2 0.032
regulation of intracellular protein transport GO:0033157 3 0.032
stem cell maintenance GO:0019827 4 0.032
regulation of mrna processing GO:0050684 3 0.031
regulation of synapse organization GO:0050807 3 0.031
nuclear migration GO:0007097 3 0.031
growth GO:0040007 174 0.030
positive regulation of catabolic process GO:0009896 4 0.030
sensory organ development GO:0007423 393 0.030
protein localization to plasma membrane GO:0072659 1 0.030
positive regulation of glucose transport GO:0010828 1 0.030
epithelial tube morphogenesis GO:0060562 148 0.030
brain development GO:0007420 293 0.029
collateral sprouting in absence of injury GO:0048669 4 0.029
transport GO:0006810 220 0.029
multicellular organism growth GO:0035264 4 0.028
establishment of protein localization to plasma membrane GO:0090002 1 0.028
proteasomal protein catabolic process GO:0010498 2 0.028
membrane fusion GO:0061025 2 0.028
cellular carbohydrate metabolic process GO:0044262 4 0.028
golgi vesicle transport GO:0048193 3 0.028
lateral inhibition GO:0046331 1 0.027
centrosome organization GO:0051297 1 0.027
organic acid metabolic process GO:0006082 31 0.027
cellular response to external stimulus GO:0071496 2 0.027
organic substance biosynthetic process GO:1901576 289 0.027
guanosine containing compound metabolic process GO:1901068 4 0.027
transmission of nerve impulse GO:0019226 19 0.027
guanosine containing compound catabolic process GO:1901069 2 0.026
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.026
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.026
gtp catabolic process GO:0006184 2 0.026
cell part morphogenesis GO:0032990 246 0.026
response to stress GO:0006950 263 0.026
fertilization GO:0009566 3 0.025
regulation of meiotic cell cycle GO:0051445 1 0.025
cytoskeleton dependent cytokinesis GO:0061640 3 0.025
regulation of reproductive process GO:2000241 4 0.025
apoptotic process involved in development GO:1902742 2 0.025
single fertilization GO:0007338 3 0.025
regulation of establishment of protein localization GO:0070201 4 0.025
regulation of cytoplasmic transport GO:1903649 4 0.025
negative regulation of biological process GO:0048519 304 0.025
establishment or maintenance of polarity of embryonic epithelium GO:0016332 2 0.025
gtp metabolic process GO:0046039 4 0.025
positive regulation of cellular catabolic process GO:0031331 3 0.025
death GO:0016265 121 0.025
regulation of rho protein signal transduction GO:0035023 2 0.025
interspecies interaction between organisms GO:0044419 4 0.025
rna metabolic process GO:0016070 219 0.024
phagocytosis GO:0006909 3 0.024
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.024
system process GO:0003008 185 0.024
central nervous system development GO:0007417 387 0.024
head development GO:0060322 303 0.023
myeloid cell differentiation GO:0030099 86 0.023
cell projection organization GO:0030030 284 0.023
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.023
cellular ketone metabolic process GO:0042180 11 0.023
regulation of stem cell differentiation GO:2000736 4 0.023
adherens junction organization GO:0034332 4 0.023
single organism metabolic process GO:0044710 217 0.023
kidney development GO:0001822 92 0.023
myeloid cell development GO:0061515 32 0.023
cognition GO:0050890 1 0.023
g1 s transition of mitotic cell cycle GO:0000082 1 0.023
regulation of apoptotic process GO:0042981 98 0.023
anterior posterior pattern specification GO:0009952 152 0.022
single organism nuclear import GO:1902593 3 0.022
regulation of cell development GO:0060284 100 0.022
tube morphogenesis GO:0035239 349 0.022
nuclear envelope organization GO:0006998 2 0.022
regulation of cell differentiation GO:0045595 142 0.022
cilium morphogenesis GO:0060271 85 0.022
cytokinesis GO:0000910 3 0.022
regulation of dendrite development GO:0050773 3 0.022
response to carbohydrate GO:0009743 3 0.021
immune system development GO:0002520 191 0.021
peptidyl serine phosphorylation GO:0018105 1 0.021
cell morphogenesis GO:0000902 289 0.021
nuclear import GO:0051170 3 0.021
heart development GO:0007507 313 0.021
homeostatic process GO:0042592 142 0.021
intracellular mrna localization GO:0008298 1 0.021
amine metabolic process GO:0009308 2 0.021
muscle structure development GO:0061061 196 0.021
carboxylic acid metabolic process GO:0019752 22 0.021
peptidyl lysine acetylation GO:0018394 2 0.021
cellular response to chemical stimulus GO:0070887 157 0.021
single organism localization GO:1902578 225 0.020
cellular aromatic compound metabolic process GO:0006725 295 0.020
gene expression GO:0010467 252 0.020
synaptic growth at neuromuscular junction GO:0051124 2 0.020
exocytosis GO:0006887 1 0.020
negative regulation of cellular process GO:0048523 283 0.020
regulation of purine nucleotide catabolic process GO:0033121 2 0.020
synaptic vesicle transport GO:0048489 1 0.020
microtubule organizing center organization GO:0031023 1 0.020
cellular component disassembly GO:0022411 1 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
regulation of metal ion transport GO:0010959 4 0.020
neuroblast proliferation GO:0007405 2 0.019
protein import into nucleus GO:0006606 3 0.019
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.019
negative regulation of kinase activity GO:0033673 4 0.019
negative regulation of ras protein signal transduction GO:0046580 1 0.019
protein acylation GO:0043543 3 0.019
rna localization GO:0006403 4 0.019
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.019
positive regulation of oocyte development GO:0060282 1 0.019
regulation of gtp catabolic process GO:0033124 2 0.019
cellular localization GO:0051641 97 0.019
regulation of multicellular organism growth GO:0040014 4 0.019
protein targeting to nucleus GO:0044744 3 0.019
actin polymerization or depolymerization GO:0008154 2 0.019
negative regulation of autophagy GO:0010507 1 0.018
protein modification process GO:0036211 100 0.018
urogenital system development GO:0001655 97 0.018
cellular nitrogen compound biosynthetic process GO:0044271 218 0.018
response to abiotic stimulus GO:0009628 122 0.018
regulation of protein localization to plasma membrane GO:1903076 1 0.018
negative regulation of protein kinase activity GO:0006469 4 0.018
cellular response to topologically incorrect protein GO:0035967 2 0.018
single organism membrane fusion GO:0044801 2 0.018
glucose import GO:0046323 2 0.018
regulation of cellular metabolic process GO:0031323 320 0.018
regulation of protein transport GO:0051223 3 0.018
adult behavior GO:0030534 2 0.018
organelle localization GO:0051640 49 0.018
regulation of oocyte development GO:0060281 3 0.018
negative regulation of cell communication GO:0010648 96 0.018
cellular response to oxygen levels GO:0071453 1 0.018
negative regulation of signal transduction GO:0009968 94 0.018
apoptotic process GO:0006915 116 0.017
cellular response to starvation GO:0009267 1 0.017
cytoplasm organization GO:0007028 4 0.017
pronuclear migration GO:0035046 1 0.017
cellular response to nutrient levels GO:0031669 2 0.017
negative regulation of catabolic process GO:0009895 3 0.017
endomembrane system organization GO:0010256 13 0.017
renal system development GO:0072001 94 0.017
hematopoietic or lymphoid organ development GO:0048534 191 0.017
regionalization GO:0003002 274 0.017
protein localization to nucleus GO:0034504 3 0.017
viral process GO:0016032 1 0.017
single organism transport GO:0044765 206 0.017
actin filament based process GO:0030029 64 0.017
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.017
cytokinetic process GO:0032506 2 0.017
gamete generation GO:0007276 33 0.016
cellular component biogenesis GO:0044085 178 0.016
carbohydrate biosynthetic process GO:0016051 1 0.016
microtubule based process GO:0007017 60 0.016
cellular response to extracellular stimulus GO:0031668 2 0.016
positive regulation of cellular process GO:0048522 201 0.016
modification of morphology or physiology of other organism GO:0035821 4 0.016
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.016
regulation of transporter activity GO:0032409 2 0.016
rho protein signal transduction GO:0007266 5 0.016
notch signaling pathway GO:0007219 35 0.015
cell proliferation GO:0008283 80 0.015
macromolecular complex subunit organization GO:0043933 74 0.015
negative regulation of mapk cascade GO:0043409 4 0.015
regulation of carbohydrate metabolic process GO:0006109 4 0.015
response to uv GO:0009411 3 0.015
multicellular organismal signaling GO:0035637 22 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
cellular amine metabolic process GO:0044106 2 0.015
regulation of primary metabolic process GO:0080090 311 0.015
positive regulation of cellular carbohydrate metabolic process GO:0010676 1 0.015
autophagy GO:0006914 4 0.015
hard palate development GO:0060022 4 0.015
erythrocyte differentiation GO:0030218 54 0.015
oxoacid metabolic process GO:0043436 31 0.015
organelle assembly GO:0070925 110 0.015
regulation of protein localization to nucleus GO:1900180 2 0.015
macromolecule modification GO:0043412 111 0.015
cellular response to decreased oxygen levels GO:0036294 1 0.015
neuronal action potential GO:0019228 18 0.015
neuroblast fate commitment GO:0014017 1 0.015
locomotor rhythm GO:0045475 3 0.015
negative regulation of intracellular protein transport GO:0090317 3 0.014
response to hexose GO:0009746 3 0.014
organonitrogen compound metabolic process GO:1901564 74 0.014
regulation of protein import into nucleus GO:0042306 2 0.014
cellular component assembly involved in morphogenesis GO:0010927 107 0.014
mesenchyme development GO:0060485 127 0.014
hormone secretion GO:0046879 2 0.014
actin cytoskeleton organization GO:0030036 63 0.014
cellular response to hypoxia GO:0071456 1 0.014
forebrain development GO:0030900 96 0.014
regulation of cellular component organization GO:0051128 86 0.014
skeletal system development GO:0001501 181 0.014
cellular macromolecule biosynthetic process GO:0034645 224 0.014
regulation of multicellular organismal development GO:2000026 223 0.014
regulation of establishment of protein localization to plasma membrane GO:0090003 1 0.014
digestive system development GO:0055123 289 0.014
regulation of cellular biosynthetic process GO:0031326 245 0.014
cellular biosynthetic process GO:0044249 286 0.014
response to glucose GO:0009749 3 0.014
negative regulation of protein import into nucleus GO:0042308 2 0.014
action potential GO:0001508 19 0.014
eye development GO:0001654 277 0.014
internal protein amino acid acetylation GO:0006475 2 0.014
internal peptidyl lysine acetylation GO:0018393 2 0.014
neuron projection morphogenesis GO:0048812 161 0.014
cell fate commitment GO:0045165 99 0.014
regulation of carbohydrate biosynthetic process GO:0043255 1 0.014
regulation of neuron differentiation GO:0045664 56 0.013
cellular protein modification process GO:0006464 100 0.013
embryonic organ development GO:0048568 381 0.013
regulation of cell communication GO:0010646 232 0.013
small molecule metabolic process GO:0044281 77 0.013
developmental growth GO:0048589 166 0.013
regulation of signaling GO:0023051 235 0.013
cell surface receptor signaling pathway GO:0007166 325 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.013
atp catabolic process GO:0006200 4 0.013
positive regulation of carbohydrate metabolic process GO:0045913 1 0.013
macromolecule biosynthetic process GO:0009059 227 0.013
programmed cell death GO:0012501 119 0.013
cell projection morphogenesis GO:0048858 244 0.013
single organism membrane organization GO:0044802 20 0.013
regulation of binding GO:0051098 3 0.013
embryonic organ morphogenesis GO:0048562 274 0.013
lipid catabolic process GO:0016042 4 0.013
forebrain cell migration GO:0021885 1 0.013
regulation of gtpase activity GO:0043087 2 0.013
morphogenesis of an epithelium GO:0002009 333 0.013
peptidyl threonine phosphorylation GO:0018107 1 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
pericardium development GO:0060039 1 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
multi organism cellular process GO:0044764 2 0.013
regulation of epithelial to mesenchymal transition GO:0010717 3 0.013
inositol lipid mediated signaling GO:0048017 2 0.012
somatic muscle development GO:0007525 4 0.012
regulation of rna biosynthetic process GO:2001141 213 0.012
stem cell proliferation GO:0072089 4 0.012
regulation of protein complex assembly GO:0043254 3 0.012
germ line stem cell division GO:0042078 1 0.012
response to alkaloid GO:0043279 2 0.012
chordate embryonic development GO:0043009 271 0.012
protein import GO:0017038 3 0.012
negative regulation of rna metabolic process GO:0051253 48 0.012
fatty acid oxidation GO:0019395 1 0.012
macromolecular complex disassembly GO:0032984 1 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
regulation of multicellular organismal process GO:0051239 277 0.012
camera type eye development GO:0043010 222 0.012
establishment of organelle localization GO:0051656 45 0.012
embryonic skeletal system development GO:0048706 97 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
stem cell division GO:0017145 1 0.012
sprouting angiogenesis GO:0002040 53 0.012
response to chemical GO:0042221 320 0.012
tube closure GO:0060606 1 0.012
protein homooligomerization GO:0051260 3 0.012
regulation of collateral sprouting in absence of injury GO:0048696 4 0.012
negative regulation of synapse assembly GO:0051964 2 0.012
p38mapk cascade GO:0038066 1 0.012
connective tissue development GO:0061448 99 0.012
positive regulation of cell division GO:0051781 2 0.012
specification of symmetry GO:0009799 204 0.012
regulation of protein catabolic process GO:0042176 1 0.012
regulation of ras gtpase activity GO:0032318 2 0.012
negative regulation of protein transport GO:0051224 3 0.012
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.012
establishment of rna localization GO:0051236 3 0.012
primary neural tube formation GO:0014020 1 0.011
organelle transport along microtubule GO:0072384 1 0.011
cellular amino acid metabolic process GO:0006520 7 0.011
branching morphogenesis of a nerve GO:0048755 4 0.011
camera type eye morphogenesis GO:0048593 108 0.011
retina development in camera type eye GO:0060041 146 0.011
sexual reproduction GO:0019953 36 0.011
negative regulation of calcium dependent cell cell adhesion GO:0046588 1 0.011
nitrogen compound metabolic process GO:0006807 319 0.011
synaptic vesicle localization GO:0097479 1 0.011
regulation of cell growth GO:0001558 29 0.011
microtubule based movement GO:0007018 33 0.011
regulation of sodium ion transport GO:0002028 2 0.011
mesoderm development GO:0007498 88 0.011
myelination GO:0042552 18 0.011
positive regulation of reproductive process GO:2000243 2 0.011
cytoskeleton organization GO:0007010 96 0.011
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.011
establishment of synaptic vesicle localization GO:0097480 1 0.011
regulation of protein complex disassembly GO:0043244 1 0.011
protein complex disassembly GO:0043241 1 0.011
cellular response to radiation GO:0071478 4 0.011
response to topologically incorrect protein GO:0035966 2 0.011
ribonucleoside monophosphate catabolic process GO:0009158 4 0.011
regulation of dendrite morphogenesis GO:0048814 3 0.011
cell substrate adhesion GO:0031589 4 0.011
organic cyclic compound biosynthetic process GO:1901362 223 0.011
cell death GO:0008219 121 0.011
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 4 0.011
regulation of protein targeting GO:1903533 2 0.011
multicellular organismal reproductive process GO:0048609 35 0.011
phosphatidylinositol mediated signaling GO:0048015 2 0.011
aromatic compound biosynthetic process GO:0019438 217 0.011
regulation of response to nutrient levels GO:0032107 1 0.011
cartilage development GO:0051216 96 0.011
negative regulation of macromolecule metabolic process GO:0010605 76 0.011
response to radiation GO:0009314 51 0.011
response to organic substance GO:0010033 153 0.011
retinoic acid biosynthetic process GO:0002138 6 0.011
immune system process GO:0002376 241 0.011
negative regulation of signaling GO:0023057 96 0.011
blood vessel development GO:0001568 246 0.011
regulation of synapse assembly GO:0051963 3 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
stem cell differentiation GO:0048863 117 0.010
negative regulation of intracellular transport GO:0032387 3 0.010
smad protein complex assembly GO:0007183 1 0.010
lipid oxidation GO:0034440 1 0.010
cortical cytoskeleton organization GO:0030865 1 0.010
central nervous system neuron differentiation GO:0021953 74 0.010
neuron projection development GO:0031175 180 0.010
regulation of organ growth GO:0046620 3 0.010
rna biosynthetic process GO:0032774 181 0.010
regulation of autophagy GO:0010506 3 0.010
maternal determination of anterior posterior axis embryo GO:0008358 4 0.010
regulation of biosynthetic process GO:0009889 250 0.010
biosynthetic process GO:0009058 294 0.010
regulation of nucleoside metabolic process GO:0009118 2 0.010
multi organism reproductive process GO:0044703 36 0.010
tissue regeneration GO:0042246 74 0.010
modification by symbiont of host morphology or physiology GO:0044003 4 0.010
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.010
retinoic acid metabolic process GO:0042573 9 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010

ppp6r2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.026
inherited metabolic disorder DOID:655 0 0.026
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010