Danio rerio

0 known processes

prdx3

peroxiredoxin 3

(Aliases: zgc:112512,wu:fk49e09,cb718,zgc:110282)

prdx3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
hydrogen peroxide metabolic process GO:0042743 2 0.648
Human
regulation of multicellular organism growth GO:0040014 4 0.510
larval development GO:0002164 2 0.491
nucleobase containing compound metabolic process GO:0006139 274 0.279
Human
aging GO:0007568 2 0.275
cellular aromatic compound metabolic process GO:0006725 295 0.275
Human
mitochondrion morphogenesis GO:0070584 2 0.247
oxidative phosphorylation GO:0006119 1 0.245
mitochondrial electron transport nadh to ubiquinone GO:0006120 1 0.225
regulation of rna biosynthetic process GO:2001141 213 0.197
Human
nucleobase containing compound biosynthetic process GO:0034654 205 0.163
Human
multicellular organism growth GO:0035264 4 0.146
nucleic acid metabolic process GO:0090304 244 0.140
Human
coenzyme biosynthetic process GO:0009108 2 0.131
cellular nitrogen compound biosynthetic process GO:0044271 218 0.121
Human
cellular respiration GO:0045333 3 0.120
cellular amino acid biosynthetic process GO:0008652 2 0.116
heterocycle metabolic process GO:0046483 290 0.110
Human
organonitrogen compound metabolic process GO:1901564 74 0.097
small molecule metabolic process GO:0044281 77 0.093
nucleic acid templated transcription GO:0097659 181 0.089
Human
regulation of cellular metabolic process GO:0031323 320 0.088
Human
organic cyclic compound metabolic process GO:1901360 301 0.083
Human
nucleotide metabolic process GO:0009117 28 0.081
developmental growth GO:0048589 166 0.078
single organism metabolic process GO:0044710 217 0.078
Human
mitochondrion organization GO:0007005 4 0.078
Human
regulation of rna metabolic process GO:0051252 224 0.078
Human
nucleobase containing small molecule metabolic process GO:0055086 32 0.075
cellular macromolecule biosynthetic process GO:0034645 224 0.074
Human
response to organic substance GO:0010033 153 0.073
Mouse
oxidation reduction process GO:0055114 41 0.071
Human
electron transport chain GO:0022900 2 0.071
response to oxidative stress GO:0006979 11 0.069
Human Mouse
nitrogen compound metabolic process GO:0006807 319 0.069
Human
hemopoiesis GO:0030097 183 0.068
Mouse
aromatic compound biosynthetic process GO:0019438 217 0.068
Human
transcription dna templated GO:0006351 181 0.066
Human
macromolecule biosynthetic process GO:0009059 227 0.066
Human
nucleoside phosphate metabolic process GO:0006753 28 0.065
negative regulation of signal transduction GO:0009968 94 0.065
mitochondrial atp synthesis coupled electron transport GO:0042775 1 0.064
biosynthetic process GO:0009058 294 0.063
Human
protein modification process GO:0036211 100 0.063
Human
organic substance biosynthetic process GO:1901576 289 0.063
Human
organic cyclic compound biosynthetic process GO:1901362 223 0.062
Human
respiratory electron transport chain GO:0022904 2 0.059
heterocycle biosynthetic process GO:0018130 215 0.056
Human
negative regulation of signaling GO:0023057 96 0.056
purine containing compound metabolic process GO:0072521 29 0.055
tube morphogenesis GO:0035239 349 0.055
dicarboxylic acid metabolic process GO:0043648 1 0.053
regulation of nitrogen compound metabolic process GO:0051171 251 0.052
Human
response to drug GO:0042493 3 0.052
regulation of reactive oxygen species metabolic process GO:2000377 2 0.051
regulation of primary metabolic process GO:0080090 311 0.050
Human
cellular response to organic substance GO:0071310 105 0.050
endoplasmic reticulum unfolded protein response GO:0030968 2 0.049
cellular biosynthetic process GO:0044249 286 0.048
Human
regulation of metabolic process GO:0019222 359 0.046
Human
oxoacid metabolic process GO:0043436 31 0.046
rna biosynthetic process GO:0032774 181 0.043
Human
organonitrogen compound biosynthetic process GO:1901566 47 0.043
purine nucleotide metabolic process GO:0006163 27 0.042
reactive oxygen species metabolic process GO:0072593 6 0.042
Human
regulation of transcription dna templated GO:0006355 213 0.041
Human
oxidoreduction coenzyme metabolic process GO:0006733 1 0.040
extrinsic apoptotic signaling pathway GO:0097191 3 0.040
stem cell proliferation GO:0072089 4 0.040
response to chemical GO:0042221 320 0.040
Human Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.039
Human
hematopoietic or lymphoid organ development GO:0048534 191 0.039
Mouse
phosphorylation GO:0016310 69 0.039
Human
phosphate containing compound metabolic process GO:0006796 108 0.039
Human
cellular nitrogen compound metabolic process GO:0034641 290 0.038
Human
phosphorus metabolic process GO:0006793 109 0.035
Human
regulation of cell activation GO:0050865 1 0.035
carbohydrate derivative metabolic process GO:1901135 61 0.035
intracellular estrogen receptor signaling pathway GO:0030520 3 0.034
regulation of cellular ketone metabolic process GO:0010565 7 0.033
establishment of localization GO:0051234 244 0.033
rna metabolic process GO:0016070 219 0.032
Human
regulation of nucleic acid templated transcription GO:1903506 213 0.032
Human
immune system process GO:0002376 241 0.032
Mouse
cell aging GO:0007569 2 0.032
negative regulation of biosynthetic process GO:0009890 55 0.032
regulation of developmental process GO:0050793 247 0.031
organic acid metabolic process GO:0006082 31 0.031
gene expression GO:0010467 252 0.030
Human
cellular protein modification process GO:0006464 100 0.030
Human
regulation of blood pressure GO:0008217 1 0.029
regulation of nucleoside metabolic process GO:0009118 2 0.029
carboxylic acid metabolic process GO:0019752 22 0.029
digestive system development GO:0055123 289 0.029
organophosphate metabolic process GO:0019637 37 0.028
coenzyme metabolic process GO:0006732 5 0.028
cellular response to chemical stimulus GO:0070887 157 0.027
Human
negative regulation of cell communication GO:0010648 96 0.026
regulation of blood vessel size GO:0050880 2 0.026
regulation of signal transduction GO:0009966 225 0.026
protein acetylation GO:0006473 2 0.026
fatty acid beta oxidation GO:0006635 1 0.025
cellular amino acid metabolic process GO:0006520 7 0.025
regulation of tube size GO:0035150 2 0.024
superoxide metabolic process GO:0006801 2 0.024
regulation of fatty acid oxidation GO:0046320 1 0.024
single organism localization GO:1902578 225 0.024
reactive nitrogen species metabolic process GO:2001057 0 0.023
cellular response to superoxide GO:0071451 2 0.023
positive regulation of cellular process GO:0048522 201 0.022
Human
reactive oxygen species biosynthetic process GO:1903409 1 0.022
embryo development ending in birth or egg hatching GO:0009792 271 0.022
atp synthesis coupled electron transport GO:0042773 1 0.022
transcription from rna polymerase ii promoter GO:0006366 80 0.022
apoptotic process GO:0006915 116 0.022
Human
alpha amino acid metabolic process GO:1901605 3 0.021
cellular ketone metabolic process GO:0042180 11 0.021
cofactor metabolic process GO:0051186 15 0.021
mitochondrial transport GO:0006839 2 0.021
small molecule catabolic process GO:0044282 3 0.021
purine ribonucleotide metabolic process GO:0009150 27 0.021
cellular response to unfolded protein GO:0034620 2 0.021
response to stress GO:0006950 263 0.020
Human Mouse
negative regulation of biological process GO:0048519 304 0.020
Human
regulation of programmed cell death GO:0043067 101 0.020
Human
maintenance of location GO:0051235 4 0.020
regulation of cellular biosynthetic process GO:0031326 245 0.020
Human
regulation of inflammatory response GO:0050727 2 0.020
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.020
Human
embryonic organ development GO:0048568 381 0.020
establishment of localization in cell GO:0051649 77 0.020
epithelial tube morphogenesis GO:0060562 148 0.019
generation of precursor metabolites and energy GO:0006091 5 0.019
proteolysis GO:0006508 38 0.019
Human
photoreceptor cell fate commitment GO:0046552 1 0.019
response to hydrogen peroxide GO:0042542 3 0.019
Human
monovalent inorganic cation transport GO:0015672 42 0.019
lipid storage GO:0019915 1 0.018
protein metabolic process GO:0019538 183 0.018
Human
zymogen activation GO:0031638 3 0.018
signal transduction GO:0007165 455 0.018
ribose phosphate metabolic process GO:0019693 27 0.018
heart looping GO:0001947 94 0.018
growth GO:0040007 174 0.018
response to other organism GO:0051707 97 0.017
Mouse
transmembrane transport GO:0055085 120 0.017
response to superoxide GO:0000303 2 0.017
adult behavior GO:0030534 2 0.017
behavior GO:0007610 74 0.017
regulation of fatty acid metabolic process GO:0019217 1 0.017
locomotion GO:0040011 313 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.017
regulation of fatty acid beta oxidation GO:0031998 1 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.017
carboxylic acid catabolic process GO:0046395 3 0.017
organic acid catabolic process GO:0016054 3 0.017
regulation of signaling GO:0023051 235 0.016
cellular component movement GO:0006928 335 0.016
cell part morphogenesis GO:0032990 246 0.016
embryonic heart tube development GO:0035050 133 0.016
phagocytosis GO:0006909 3 0.016
acyl coa metabolic process GO:0006637 1 0.016
response to oxygen radical GO:0000305 2 0.016
positive regulation of macromolecule metabolic process GO:0010604 93 0.016
multi organism process GO:0051704 134 0.016
Mouse
ion transport GO:0006811 114 0.016
positive regulation of metabolic process GO:0009893 108 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.015
cellular protein metabolic process GO:0044267 129 0.015
Human
regulation of multicellular organismal process GO:0051239 277 0.015
digestive tract development GO:0048565 265 0.015
multicellular organismal macromolecule metabolic process GO:0044259 2 0.015
fatty acid oxidation GO:0019395 1 0.015
positive regulation of multicellular organismal process GO:0051240 52 0.014
endocytosis GO:0006897 16 0.014
single organism biosynthetic process GO:0044711 71 0.014
generation of neurons GO:0048699 385 0.014
regulation of growth GO:0040008 42 0.014
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.014
positive regulation of map kinase activity GO:0043406 3 0.014
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.014
regulation of apoptotic process GO:0042981 98 0.014
Human
protein acylation GO:0043543 3 0.013
neuroblast proliferation GO:0007405 2 0.013
response to external biotic stimulus GO:0043207 97 0.013
Mouse
negative regulation of leukocyte differentiation GO:1902106 1 0.013
acetyl coa metabolic process GO:0006084 1 0.013
death GO:0016265 121 0.013
Human
intracellular signal transduction GO:0035556 85 0.013
positive regulation of cellular metabolic process GO:0031325 94 0.013
removal of superoxide radicals GO:0019430 2 0.012
smooth muscle contraction GO:0006939 2 0.012
response to wounding GO:0009611 116 0.012
intracellular receptor signaling pathway GO:0030522 30 0.012
regulation of developmental growth GO:0048638 38 0.012
atp metabolic process GO:0046034 5 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.012
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.012
Human
determination of left right symmetry GO:0007368 179 0.012
negative regulation of kinase activity GO:0033673 4 0.012
Human
cellular macromolecule metabolic process GO:0044260 391 0.012
Human
regulation of cell differentiation GO:0045595 142 0.012
eye development GO:0001654 277 0.012
response to oxygen levels GO:0070482 25 0.012
macromolecule modification GO:0043412 111 0.012
Human
negative regulation of nucleic acid templated transcription GO:1903507 45 0.011
cell proliferation GO:0008283 80 0.011
Human
regulation of nucleotide metabolic process GO:0006140 17 0.011
positive regulation of cell activation GO:0050867 1 0.011
negative regulation of rna metabolic process GO:0051253 48 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
Human
transport GO:0006810 220 0.011
morphogenesis of an epithelium GO:0002009 333 0.011
regulation of peptidase activity GO:0052547 23 0.011
Human
cell motility GO:0048870 244 0.011
regulation of biosynthetic process GO:0009889 250 0.011
Human
activation of mapk activity GO:0000187 3 0.011
post embryonic development GO:0009791 7 0.011
regulation of jun kinase activity GO:0043506 3 0.011
cellular component morphogenesis GO:0032989 336 0.011
regulation of systemic arterial blood pressure GO:0003073 1 0.011
gtp metabolic process GO:0046039 4 0.011
positive regulation of programmed cell death GO:0043068 29 0.011
heart development GO:0007507 313 0.011
regulation of response to stimulus GO:0048583 269 0.011
regulation of gene expression GO:0010468 265 0.011
Human
cellular protein catabolic process GO:0044257 4 0.011
cell differentiation in spinal cord GO:0021515 40 0.011
cellular response to oxygen radical GO:0071450 2 0.011
negative regulation of response to stimulus GO:0048585 104 0.010
immune system development GO:0002520 191 0.010
Mouse
cellular amine metabolic process GO:0044106 2 0.010
regulation of blood coagulation GO:0030193 1 0.010
positive regulation of developmental process GO:0051094 50 0.010
response to nutrient GO:0007584 3 0.010
amine metabolic process GO:0009308 2 0.010
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.010

prdx3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.334
mitochondrial metabolism disease DOID:700 0 0.334
inherited metabolic disorder DOID:655 0 0.334
leigh disease DOID:3652 0 0.219
cancer DOID:162 0 0.042
disease of cellular proliferation DOID:14566 0 0.042
organ system cancer DOID:0050686 0 0.041
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.035
endocrine gland cancer DOID:170 0 0.027
amino acid metabolic disorder DOID:9252 0 0.023