Danio rerio

0 known processes

prdx4

peroxiredoxin 4

(Aliases: wu:fb59c09,zgc:162938,fb59c09)

prdx4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to superoxide GO:0071451 2 0.184
organonitrogen compound biosynthetic process GO:1901566 47 0.162
organonitrogen compound metabolic process GO:1901564 74 0.160
Mouse
regulation of multicellular organism growth GO:0040014 4 0.140
Worm
cellular biosynthetic process GO:0044249 286 0.138
Worm
multicellular organism growth GO:0035264 4 0.133
Worm
nitrogen compound metabolic process GO:0006807 319 0.125
Mouse Worm
nucleobase containing compound metabolic process GO:0006139 274 0.106
Worm
maintenance of location GO:0051235 4 0.087
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.082
cellular nitrogen compound metabolic process GO:0034641 290 0.081
Worm
response to oxygen radical GO:0000305 2 0.076
regulation of rna metabolic process GO:0051252 224 0.059
Worm
zymogen activation GO:0031638 3 0.058
cellular response to lipopolysaccharide GO:0071222 3 0.056
gene expression GO:0010467 252 0.054
Mouse Worm
cellular nitrogen compound biosynthetic process GO:0044271 218 0.045
Worm
rna metabolic process GO:0016070 219 0.045
Worm
aging GO:0007568 2 0.044
Worm
macromolecule biosynthetic process GO:0009059 227 0.043
Worm
cellular macromolecule metabolic process GO:0044260 391 0.043
Mouse Worm
sensory organ development GO:0007423 393 0.041
regulation of sodium ion transport GO:0002028 2 0.039
regulation of rna biosynthetic process GO:2001141 213 0.037
Worm
regulation of cellular amine metabolic process GO:0033238 0 0.036
cell surface receptor signaling pathway GO:0007166 325 0.036
gland development GO:0048732 143 0.035
protein stabilization GO:0050821 2 0.035
ribose phosphate biosynthetic process GO:0046390 20 0.034
hemopoiesis GO:0030097 183 0.034
positive regulation of transport GO:0051050 2 0.034
regulation of lyase activity GO:0051339 12 0.033
digestive tract development GO:0048565 265 0.033
response to stress GO:0006950 263 0.032
Worm
cellular response to biotic stimulus GO:0071216 3 0.032
camera type eye development GO:0043010 222 0.031
developmental growth GO:0048589 166 0.030
Worm
regulation of macromolecule metabolic process GO:0060255 317 0.030
Worm
organic substance biosynthetic process GO:1901576 289 0.029
Worm
lipid storage GO:0019915 1 0.029
biosynthetic process GO:0009058 294 0.029
Worm
carbohydrate derivative biosynthetic process GO:1901137 43 0.028
homeostasis of number of cells GO:0048872 62 0.028
digestive system development GO:0055123 289 0.028
cell aging GO:0007569 2 0.027
adult behavior GO:0030534 2 0.027
hematopoietic or lymphoid organ development GO:0048534 191 0.027
extrinsic apoptotic signaling pathway GO:0097191 3 0.026
nucleobase containing compound biosynthetic process GO:0034654 205 0.026
Worm
sensory organ morphogenesis GO:0090596 200 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
amine metabolic process GO:0009308 2 0.025
cellular response to estrogen stimulus GO:0071391 24 0.024
regulation of multicellular organismal process GO:0051239 277 0.024
Mouse Worm
peptidyl serine modification GO:0018209 2 0.024
organic cyclic compound metabolic process GO:1901360 301 0.024
Mouse Worm
regulation of establishment of protein localization GO:0070201 4 0.024
lymphocyte homeostasis GO:0002260 1 0.024
regulation of nucleoside metabolic process GO:0009118 2 0.023
heterocycle biosynthetic process GO:0018130 215 0.022
Worm
cellular response to molecule of bacterial origin GO:0071219 3 0.022
regulation of response to biotic stimulus GO:0002831 2 0.022
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.022
Worm
mononuclear cell proliferation GO:0032943 1 0.022
cellular aromatic compound metabolic process GO:0006725 295 0.022
Worm
ribonucleoside biosynthetic process GO:0042455 2 0.022
response to external stimulus GO:0009605 264 0.021
transcription dna templated GO:0006351 181 0.021
Worm
negative regulation of metabolic process GO:0009892 86 0.021
Worm
regulation of peptidase activity GO:0052547 23 0.020
positive regulation of cellular catabolic process GO:0031331 3 0.020
generation of neurons GO:0048699 385 0.020
positive regulation of apoptotic signaling pathway GO:2001235 1 0.020
cellular ketone metabolic process GO:0042180 11 0.020
head development GO:0060322 303 0.019
positive regulation of gtp catabolic process GO:0033126 1 0.019
positive regulation of metabolic process GO:0009893 108 0.019
response to chemical GO:0042221 320 0.019
Worm
positive regulation of cell communication GO:0010647 56 0.019
positive regulation of nucleoside metabolic process GO:0045979 1 0.019
cellular response to lipid GO:0071396 39 0.019
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.018
hydrogen peroxide metabolic process GO:0042743 2 0.018
Worm
superoxide metabolic process GO:0006801 2 0.018
nucleocytoplasmic transport GO:0006913 4 0.017
organic cyclic compound biosynthetic process GO:1901362 223 0.017
Worm
ion transport GO:0006811 114 0.017
positive regulation of catabolic process GO:0009896 4 0.017
embryonic organ development GO:0048568 381 0.017
monovalent inorganic cation transport GO:0015672 42 0.017
regulation of transmembrane transporter activity GO:0022898 2 0.017
anion transport GO:0006820 38 0.016
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.016
Worm
retina development in camera type eye GO:0060041 146 0.016
cellular response to organic cyclic compound GO:0071407 38 0.016
leukocyte homeostasis GO:0001776 2 0.016
heterocycle metabolic process GO:0046483 290 0.016
Mouse Worm
regulation of cellular metabolic process GO:0031323 320 0.016
Worm
eye development GO:0001654 277 0.016
nucleoside triphosphate biosynthetic process GO:0009142 2 0.016
specification of symmetry GO:0009799 204 0.015
neuron differentiation GO:0030182 353 0.015
regulation of gtp catabolic process GO:0033124 2 0.015
neurotransmitter transport GO:0006836 2 0.015
digestive tract mesoderm development GO:0007502 1 0.015
cell proliferation GO:0008283 80 0.015
Mouse
nucleic acid metabolic process GO:0090304 244 0.015
Worm
leukocyte proliferation GO:0070661 1 0.015
regulation of nitrogen compound metabolic process GO:0051171 251 0.015
Worm
signal transduction GO:0007165 455 0.015
cellular response to organic substance GO:0071310 105 0.014
cellular response to chemical stimulus GO:0070887 157 0.014
Worm
single organism metabolic process GO:0044710 217 0.014
Mouse Worm
regulation of transporter activity GO:0032409 2 0.014
epithelial cell morphogenesis GO:0003382 2 0.014
positive regulation of lyase activity GO:0051349 6 0.014
purine nucleoside triphosphate biosynthetic process GO:0009145 2 0.014
rna biosynthetic process GO:0032774 181 0.014
Worm
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
positive regulation of developmental process GO:0051094 50 0.014
Worm
regulation of blood pressure GO:0008217 1 0.014
immune system development GO:0002520 191 0.014
cellular amine metabolic process GO:0044106 2 0.014
immune system process GO:0002376 241 0.014
energy reserve metabolic process GO:0006112 2 0.014
single organism biosynthetic process GO:0044711 71 0.013
negative regulation of cellular process GO:0048523 283 0.013
Mouse Worm
morphogenesis of an epithelium GO:0002009 333 0.013
cellular component biogenesis GO:0044085 178 0.013
regulation of cytokine production GO:0001817 3 0.013
larval development GO:0002164 2 0.013
positive regulation of programmed cell death GO:0043068 29 0.013
purine ribonucleoside biosynthetic process GO:0046129 2 0.013
nucleoside biosynthetic process GO:0009163 2 0.013
carboxylic acid metabolic process GO:0019752 22 0.013
Mouse
regulation of cellular ketone metabolic process GO:0010565 7 0.013
oxoacid metabolic process GO:0043436 31 0.013
Mouse
cellular amino acid biosynthetic process GO:0008652 2 0.013
guanosine containing compound metabolic process GO:1901068 4 0.013
nucleic acid templated transcription GO:0097659 181 0.013
Worm
type b pancreatic cell development GO:0003323 4 0.012
modification dependent macromolecule catabolic process GO:0043632 3 0.012
regulation of gtpase activity GO:0043087 2 0.012
positive regulation of multi organism process GO:0043902 3 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
nuclear export GO:0051168 1 0.012
negative regulation of apoptotic process GO:0043066 55 0.012
purine ribonucleoside triphosphate biosynthetic process GO:0009206 2 0.012
response to lipid GO:0033993 60 0.012
regulation of biosynthetic process GO:0009889 250 0.012
Worm
ribonucleotide biosynthetic process GO:0009260 20 0.012
ion transmembrane transport GO:0034220 91 0.012
fatty acid transport GO:0015908 1 0.012
nuclear transport GO:0051169 4 0.012
adherens junction organization GO:0034332 4 0.012
regulation of muscle hypertrophy GO:0014743 2 0.011
regulation of primary metabolic process GO:0080090 311 0.011
Worm
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.011
lymphocyte proliferation GO:0046651 1 0.011
regulation of biological quality GO:0065008 263 0.011
Mouse
transmembrane transport GO:0055085 120 0.011
regulation of protein ubiquitination GO:0031396 3 0.011
positive regulation of signal transduction GO:0009967 56 0.011
regulation of developmental growth GO:0048638 38 0.011
Worm
regulation of protein catabolic process GO:0042176 1 0.011
positive regulation of multicellular organismal process GO:0051240 52 0.011
Worm
proteasomal protein catabolic process GO:0010498 2 0.011
purine ribonucleotide metabolic process GO:0009150 27 0.011
epidermal cell differentiation GO:0009913 36 0.011
positive regulation of immune effector process GO:0002699 3 0.011
long chain fatty acid transport GO:0015909 1 0.011
regulation of cell activation GO:0050865 1 0.011
response to hormone GO:0009725 48 0.011
chromosome organization involved in meiosis GO:0070192 1 0.011
rna 3 end processing GO:0031123 2 0.011
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.011
negative regulation of cytoplasmic transport GO:1903650 2 0.011
protein localization to nucleus GO:0034504 3 0.010
regulation of metal ion transport GO:0010959 4 0.010
regulation of transcription dna templated GO:0006355 213 0.010
Worm
exocrine pancreas development GO:0031017 28 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.010
negative regulation of multi organism process GO:0043901 3 0.010
Mouse
heart development GO:0007507 313 0.010
organophosphate biosynthetic process GO:0090407 23 0.010
lateral inhibition GO:0046331 1 0.010
neuron development GO:0048666 262 0.010
negative regulation of catabolic process GO:0009895 3 0.010

prdx4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 0 0.059
disease of anatomical entity DOID:7 0 0.059
bone marrow disease DOID:4961 0 0.059
hematopoietic system disease DOID:74 0 0.059
aplastic anemia DOID:12449 0 0.032
anemia DOID:2355 0 0.032
congenital hypoplastic anemia DOID:1342 0 0.021
diamond blackfan anemia DOID:1339 0 0.017
nervous system disease DOID:863 0 0.017
disease of metabolism DOID:0014667 0 0.015
amino acid metabolic disorder DOID:9252 0 0.010
inherited metabolic disorder DOID:655 0 0.010