Danio rerio

0 known processes

prkaa1

protein kinase, AMP-activated, alpha 1 catalytic subunit

(Aliases: cb116,im:7154392,sb:cb130,wu:fa94c10)

prkaa1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of rna biosynthetic process GO:2001141 213 0.477
regulation of cellular biosynthetic process GO:0031326 245 0.470
Yeast
regulation of biosynthetic process GO:0009889 250 0.352
Yeast
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.341
cellular macromolecule metabolic process GO:0044260 391 0.336
Human Yeast Mouse Rat Worm Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.333
cellular macromolecule biosynthetic process GO:0034645 224 0.331
Yeast
biosynthetic process GO:0009058 294 0.294
Yeast Mouse
regulation of establishment of protein localization GO:0070201 4 0.290
gastrulation GO:0007369 208 0.279
cellular component movement GO:0006928 335 0.269
Fly
organic cyclic compound metabolic process GO:1901360 301 0.250
transport GO:0006810 220 0.246
Rat Fly
regulation of nucleic acid templated transcription GO:1903506 213 0.234
cellular nitrogen compound metabolic process GO:0034641 290 0.229
regulation of rna metabolic process GO:0051252 224 0.218
nucleobase containing compound metabolic process GO:0006139 274 0.215
phosphorus metabolic process GO:0006793 109 0.214
Human Yeast Mouse Rat Worm Fly
signal transduction GO:0007165 455 0.212
Mouse
positive regulation of transport GO:0051050 2 0.211
regulation of macromolecule biosynthetic process GO:0010556 225 0.202
Yeast
nucleic acid templated transcription GO:0097659 181 0.200
ion transport GO:0006811 114 0.197
cellular aromatic compound metabolic process GO:0006725 295 0.184
regulation of macromolecule metabolic process GO:0060255 317 0.181
Human Yeast Rat
nitrogen compound metabolic process GO:0006807 319 0.175
gene expression GO:0010467 252 0.173
Human Yeast
cellular biosynthetic process GO:0044249 286 0.171
Yeast
organic substance biosynthetic process GO:1901576 289 0.170
Yeast Mouse
cell morphogenesis involved in differentiation GO:0000904 195 0.170
Fly
regulation of establishment of protein localization to plasma membrane GO:0090003 1 0.169
single organism localization GO:1902578 225 0.169
Rat Fly
establishment of localization GO:0051234 244 0.168
Rat Fly
regulation of cellular metabolic process GO:0031323 320 0.167
Yeast Mouse Rat
larval development GO:0002164 2 0.166
Worm
regulation of primary metabolic process GO:0080090 311 0.164
Yeast Mouse Rat
positive regulation of cell cycle GO:0045787 3 0.159
Worm
tube morphogenesis GO:0035239 349 0.158
convergent extension involved in gastrulation GO:0060027 71 0.156
phagocytosis GO:0006909 3 0.153
Fly
negative regulation of biological process GO:0048519 304 0.150
Yeast Mouse Rat Worm
cellular localization GO:0051641 97 0.150
rna biosynthetic process GO:0032774 181 0.148
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.145
Yeast
cell surface receptor signaling pathway GO:0007166 325 0.136
cellular ketone metabolic process GO:0042180 11 0.135
Yeast
regulation of localization GO:0032879 104 0.133
Rat
rna metabolic process GO:0016070 219 0.132
nuclear transport GO:0051169 4 0.132
heterocycle metabolic process GO:0046483 290 0.129
macromolecule biosynthetic process GO:0009059 227 0.127
Yeast
ameboidal type cell migration GO:0001667 143 0.126
digestive tract morphogenesis GO:0048546 231 0.121
cell cycle GO:0007049 93 0.121
Worm Fly
nucleocytoplasmic transport GO:0006913 4 0.121
macromolecule localization GO:0033036 54 0.120
Fly
regulation of response to stimulus GO:0048583 269 0.119
Yeast Mouse Rat
mitotic cell cycle GO:0000278 64 0.119
Worm Fly
locomotion GO:0040011 313 0.116
Fly
cellular protein modification process GO:0006464 100 0.115
Human Yeast Mouse Rat Worm Fly
response to light stimulus GO:0009416 46 0.115
Mouse Fly
protein localization to nucleus GO:0034504 3 0.111
transcription dna templated GO:0006351 181 0.111
peptidyl serine phosphorylation GO:0018105 1 0.111
Mouse Worm
digestive system development GO:0055123 289 0.111
cellular nitrogen compound biosynthetic process GO:0044271 218 0.110
heterocycle biosynthetic process GO:0018130 215 0.110
regulation of multicellular organismal development GO:2000026 223 0.110
Worm
phosphate containing compound metabolic process GO:0006796 108 0.109
Human Yeast Mouse Rat Worm Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.109
nuclear import GO:0051170 3 0.108
negative regulation of response to stimulus GO:0048585 104 0.108
Mouse Rat
protein metabolic process GO:0019538 183 0.108
Human Yeast Mouse Rat Worm Fly
response to chemical GO:0042221 320 0.108
Mouse Rat Fly
formation of primary germ layer GO:0001704 62 0.108
cellular carbohydrate metabolic process GO:0044262 4 0.107
Yeast Rat
regulation of signaling GO:0023051 235 0.107
Mouse
establishment of protein localization to plasma membrane GO:0090002 1 0.106
regulation of multicellular organismal process GO:0051239 277 0.105
Zebrafish Rat Worm Fly
positive regulation of biological process GO:0048518 253 0.104
Human Yeast Mouse Rat Worm
regulation of metabolic process GO:0019222 359 0.101
Human Yeast Mouse Rat
protein import into nucleus GO:0006606 3 0.100
aromatic compound biosynthetic process GO:0019438 217 0.098
extrinsic apoptotic signaling pathway GO:0097191 3 0.097
regulation of cell communication GO:0010646 232 0.096
Mouse
regulation of transport GO:0051049 45 0.096
Rat
protein import GO:0017038 3 0.095
regulation of protein transport GO:0051223 3 0.094
regulation of transcription dna templated GO:0006355 213 0.094
nucleic acid metabolic process GO:0090304 244 0.093
generation of neurons GO:0048699 385 0.093
Fly
organonitrogen compound metabolic process GO:1901564 74 0.092
positive regulation of response to stimulus GO:0048584 80 0.091
Yeast
amine metabolic process GO:0009308 2 0.089
establishment of protein localization to organelle GO:0072594 4 0.087
myeloid cell differentiation GO:0030099 86 0.087
Zebrafish
neuron development GO:0048666 262 0.084
Fly
lipid homeostasis GO:0055088 3 0.084
Rat
regulation of cell differentiation GO:0045595 142 0.080
chordate embryonic development GO:0043009 271 0.077
positive regulation of cellular process GO:0048522 201 0.077
Yeast Mouse Rat Worm
neuron projection morphogenesis GO:0048812 161 0.076
Fly
cell morphogenesis GO:0000902 289 0.076
Fly
protein targeting to nucleus GO:0044744 3 0.075
nucleobase containing compound biosynthetic process GO:0034654 205 0.074
single organism nuclear import GO:1902593 3 0.074
lateral line development GO:0048882 66 0.073
regulation of nucleocytoplasmic transport GO:0046822 2 0.073
negative regulation of cellular process GO:0048523 283 0.072
Yeast Mouse Rat Worm
microtubule based process GO:0007017 60 0.070
regulation of gene expression GO:0010468 265 0.070
Human Yeast
regulation of meiotic cell cycle GO:0051445 1 0.069
Worm
intracellular signal transduction GO:0035556 85 0.069
Mouse
glucose homeostasis GO:0042593 1 0.068
Mouse
cell projection morphogenesis GO:0048858 244 0.068
Fly
chemotaxis GO:0006935 104 0.067
Fly
regulation of cytoplasmic transport GO:1903649 4 0.066
negative regulation of signaling GO:0023057 96 0.066
Mouse
axon development GO:0061564 166 0.066
Fly
regulation of intracellular protein transport GO:0033157 3 0.066
single organism transport GO:0044765 206 0.066
Rat Fly
blood vessel morphogenesis GO:0048514 216 0.065
organelle localization GO:0051640 49 0.065
cell motility GO:0048870 244 0.063
negative regulation of protein phosphorylation GO:0001933 4 0.062
protein localization to plasma membrane GO:0072659 1 0.062
negative regulation of cell communication GO:0010648 96 0.061
Mouse
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.060
Yeast Rat
vasculature development GO:0001944 278 0.059
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.059
response to radiation GO:0009314 51 0.058
Mouse Fly
regulation of metal ion transport GO:0010959 4 0.058
single organism cellular localization GO:1902580 46 0.058
heart morphogenesis GO:0003007 156 0.057
single organism metabolic process GO:0044710 217 0.057
Yeast Mouse Rat Fly
immune system process GO:0002376 241 0.057
Zebrafish
autophagy GO:0006914 4 0.057
Mouse
localization of cell GO:0051674 244 0.056
cell projection organization GO:0030030 284 0.056
Fly
regulation of phosphorus metabolic process GO:0051174 43 0.055
regulation of protein metabolic process GO:0051246 56 0.054
Yeast
cellular response to endogenous stimulus GO:0071495 68 0.054
Rat
morphogenesis of an epithelium GO:0002009 333 0.054
cytokinesis GO:0000910 3 0.053
regulation of cell development GO:0060284 100 0.053
regulation of cellular amine metabolic process GO:0033238 0 0.053
establishment or maintenance of cell polarity GO:0007163 29 0.053
Fly
homeostatic process GO:0042592 142 0.052
Zebrafish Mouse Rat
regulation of developmental process GO:0050793 247 0.052
Worm
regulation of intracellular signal transduction GO:1902531 57 0.052
Mouse
regulation of biological quality GO:0065008 263 0.051
Zebrafish Mouse Rat Fly
modification dependent protein catabolic process GO:0019941 3 0.051
cellular amine metabolic process GO:0044106 2 0.050
determination of dorsal ventral asymmetry GO:0048262 34 0.050
stem cell division GO:0017145 1 0.050
negative regulation of metabolic process GO:0009892 86 0.050
Yeast Mouse
immune system development GO:0002520 191 0.050
Zebrafish
positive regulation of catabolic process GO:0009896 4 0.049
Mouse Rat
system process GO:0003008 185 0.049
Zebrafish Fly
axon guidance GO:0007411 86 0.049
Fly
negative regulation of signal transduction GO:0009968 94 0.049
Mouse
small molecule metabolic process GO:0044281 77 0.048
Yeast Mouse Rat
establishment of localization in cell GO:0051649 77 0.048
regulation of protein localization to nucleus GO:1900180 2 0.048
regulation of signal transduction GO:0009966 225 0.048
Mouse
positive regulation of map kinase activity GO:0043406 3 0.047
regulation of phosphate metabolic process GO:0019220 43 0.046
positive regulation of cellular catabolic process GO:0031331 3 0.045
Mouse Rat
response to organic substance GO:0010033 153 0.045
Mouse Rat
axonogenesis GO:0007409 152 0.044
Fly
regulation of carbohydrate metabolic process GO:0006109 4 0.044
Yeast Rat
cortical cytoskeleton organization GO:0030865 1 0.044
regulation of catalytic activity GO:0050790 55 0.044
response to uv GO:0009411 3 0.044
Mouse
enzyme linked receptor protein signaling pathway GO:0007167 106 0.044
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.043
regulation of cytokine production GO:0001817 3 0.043
multi organism process GO:0051704 134 0.043
Yeast
cell migration GO:0016477 237 0.042
adherens junction organization GO:0034332 4 0.042
response to abiotic stimulus GO:0009628 122 0.042
Mouse Rat Fly
regulation of cellular protein metabolic process GO:0032268 52 0.042
Yeast
taxis GO:0042330 109 0.041
Fly
convergent extension GO:0060026 118 0.041
cell migration involved in gastrulation GO:0042074 79 0.041
response to carbohydrate GO:0009743 3 0.041
cellular component morphogenesis GO:0032989 336 0.040
Fly
regulation of jak stat cascade GO:0046425 3 0.040
cation transport GO:0006812 81 0.040
cellular response to organic substance GO:0071310 105 0.040
Rat
multicellular organism growth GO:0035264 4 0.039
regulation of ion transmembrane transporter activity GO:0032412 2 0.039
organic substance transport GO:0071702 58 0.038
Rat
positive regulation of signaling GO:0023056 56 0.038
regulation of molecular function GO:0065009 70 0.038
sprouting angiogenesis GO:0002040 53 0.038
hemopoiesis GO:0030097 183 0.038
Zebrafish
regulation of reproductive process GO:2000241 4 0.038
triglyceride homeostasis GO:0070328 2 0.038
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.037
stem cell maintenance GO:0019827 4 0.037
carboxylic acid metabolic process GO:0019752 22 0.037
Mouse Rat
response to alkaloid GO:0043279 2 0.037
Mouse Rat
regulation of transporter activity GO:0032409 2 0.037
regulation of phospholipase c activity GO:1900274 1 0.036
apoptotic process GO:0006915 116 0.036
Mouse
digestive tract development GO:0048565 265 0.036
membrane invagination GO:0010324 1 0.035
neuron projection guidance GO:0097485 86 0.035
Fly
cellular protein catabolic process GO:0044257 4 0.035
oxoacid metabolic process GO:0043436 31 0.035
Mouse Rat
endoderm development GO:0007492 49 0.035
phagocytosis engulfment GO:0006911 1 0.034
positive regulation of multi organism process GO:0043902 3 0.034
negative regulation of sequestering of calcium ion GO:0051283 4 0.034
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.034
cellular protein metabolic process GO:0044267 129 0.034
Human Yeast Mouse Rat Worm Fly
positive regulation of signal transduction GO:0009967 56 0.034
cellular response to chemical stimulus GO:0070887 157 0.034
Rat
central nervous system development GO:0007417 387 0.034
regulation of protein localization to plasma membrane GO:1903076 1 0.033
response to stress GO:0006950 263 0.033
Yeast Mouse Rat Fly
cell substrate adhesion GO:0031589 4 0.033
regulation of embryonic development GO:0045995 47 0.032
gland development GO:0048732 143 0.032
positive regulation of cellular metabolic process GO:0031325 94 0.032
Yeast Mouse Rat
meiotic nuclear division GO:0007126 4 0.031
regulation of cellular amino acid metabolic process GO:0006521 0 0.031
cellular response to stress GO:0033554 62 0.031
Yeast Mouse Rat Fly
membrane organization GO:0061024 21 0.031
embryonic organ morphogenesis GO:0048562 274 0.031
aging GO:0007568 2 0.031
Yeast Worm
tissue remodeling GO:0048771 4 0.031
regionalization GO:0003002 274 0.031
tyrosine phosphorylation of stat protein GO:0007260 1 0.031
regulation of mitotic cell cycle GO:0007346 25 0.030
Worm
determination of bilateral symmetry GO:0009855 204 0.030
synaptic growth at neuromuscular junction GO:0051124 2 0.030
germ line stem cell maintenance GO:0030718 2 0.030
ear development GO:0043583 127 0.030
regulation of neurogenesis GO:0050767 87 0.030
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.030
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.030
golgi vesicle transport GO:0048193 3 0.030
positive regulation of metabolic process GO:0009893 108 0.030
Human Yeast Mouse Rat
positive regulation of cellular component biogenesis GO:0044089 3 0.030
response to amino acid GO:0043200 2 0.030
regulation of cellular ketone metabolic process GO:0010565 7 0.030
Yeast
neuron projection development GO:0031175 180 0.029
Fly
protein localization GO:0008104 40 0.029
lipid catabolic process GO:0016042 4 0.029
Mouse
organic acid metabolic process GO:0006082 31 0.029
Mouse Rat
negative regulation of intracellular signal transduction GO:1902532 22 0.029
Mouse
protein dephosphorylation GO:0006470 3 0.029
organelle organization GO:0006996 227 0.029
Mouse
cellular component disassembly GO:0022411 1 0.028
hepaticobiliary system development GO:0061008 98 0.028
regulation of protein import into nucleus GO:0042306 2 0.028
positive regulation of muscle organ development GO:0048636 1 0.028
negative regulation of mapk cascade GO:0043409 4 0.028
regulation of transmembrane transporter activity GO:0022898 2 0.028
modification dependent macromolecule catabolic process GO:0043632 3 0.027
mitochondrion organization GO:0007005 4 0.027
regulation of dendrite development GO:0050773 3 0.027
cell part morphogenesis GO:0032990 246 0.027
Fly
cytoskeleton organization GO:0007010 96 0.027
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.027
cellular protein localization GO:0034613 20 0.027
er to golgi vesicle mediated transport GO:0006888 1 0.027
positive regulation of cellular amine metabolic process GO:0033240 0 0.027
macromolecular complex disassembly GO:0032984 1 0.026
regulation of ion transport GO:0043269 22 0.026
pyruvate metabolic process GO:0006090 1 0.026
Rat
spindle localization GO:0051653 12 0.026
erk1 and erk2 cascade GO:0070371 4 0.026
regulation of multicellular organism growth GO:0040014 4 0.025
cellular response to biotic stimulus GO:0071216 3 0.025
positive regulation of molecular function GO:0044093 33 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.025
neurotransmitter secretion GO:0007269 2 0.025
mesenchyme development GO:0060485 127 0.025
regulation of epithelial cell proliferation GO:0050678 3 0.025
determination of left right symmetry GO:0007368 179 0.025
hormone biosynthetic process GO:0042446 3 0.025
regulation of response to stress GO:0080134 36 0.024
Yeast
small gtpase mediated signal transduction GO:0007264 8 0.024
regulation of transferase activity GO:0051338 16 0.024
positive regulation of leukocyte differentiation GO:1902107 1 0.024
transcription from rna polymerase ii promoter GO:0006366 80 0.024
fertilization GO:0009566 3 0.024
circadian sleep wake cycle process GO:0022410 2 0.024
cellular macromolecule localization GO:0070727 21 0.024
cell matrix adhesion GO:0007160 4 0.024
proteasomal protein catabolic process GO:0010498 2 0.024
actin cytoskeleton organization GO:0030036 63 0.024
positive regulation of biosynthetic process GO:0009891 68 0.024
Yeast
positive regulation of cell communication GO:0010647 56 0.024
positive regulation of oocyte development GO:0060282 1 0.024
protein secretion GO:0009306 1 0.024
heart development GO:0007507 313 0.024
negative regulation of protein complex assembly GO:0031333 1 0.024
establishment of organelle localization GO:0051656 45 0.023
regulation of protein phosphorylation GO:0001932 18 0.023
regulation of synaptic plasticity GO:0048167 1 0.023
maintenance of location GO:0051235 4 0.023
Fly
cellular amino acid metabolic process GO:0006520 7 0.023
phosphorylation GO:0016310 69 0.023
Human Yeast Mouse Rat Worm Fly
regulation of protein complex assembly GO:0043254 3 0.023
ubiquitin dependent protein catabolic process GO:0006511 3 0.023
negative regulation of gene expression GO:0010629 65 0.023
Yeast
cortical actin cytoskeleton organization GO:0030866 1 0.023
neurological system process GO:0050877 62 0.023
liver development GO:0001889 96 0.023
positive regulation of catalytic activity GO:0043085 25 0.022
dorsal ventral pattern formation GO:0009953 125 0.022
regulation of oocyte development GO:0060281 3 0.022
regulation of cellular response to growth factor stimulus GO:0090287 35 0.022
response to external stimulus GO:0009605 264 0.022
Yeast Mouse Fly
negative regulation of protein kinase activity GO:0006469 4 0.022
cell migration involved in heart development GO:0060973 22 0.022
protein complex disassembly GO:0043241 1 0.022
negative regulation of rna metabolic process GO:0051253 48 0.022
negative regulation of developmental process GO:0051093 65 0.022
response to hexose GO:0009746 3 0.022
epidermal cell differentiation GO:0009913 36 0.022
negative regulation of ras protein signal transduction GO:0046580 1 0.022
regulation of posttranscriptional gene silencing GO:0060147 1 0.021
regulation of binding GO:0051098 3 0.021
regulation of sequestering of calcium ion GO:0051282 4 0.021
regulation of mapk cascade GO:0043408 14 0.021
kidney development GO:0001822 92 0.021
multicellular organismal homeostasis GO:0048871 29 0.021
Rat
sequestering of metal ion GO:0051238 3 0.021
regulation of protein catabolic process GO:0042176 1 0.021
hematopoietic or lymphoid organ development GO:0048534 191 0.020
Zebrafish
regulation of protein targeting GO:1903533 2 0.020
regulation of apoptotic process GO:0042981 98 0.020
Mouse
regulation of receptor activity GO:0010469 2 0.020
microtubule cytoskeleton organization GO:0000226 33 0.020
positive regulation of macromolecule metabolic process GO:0010604 93 0.020
Human
embryonic cranial skeleton morphogenesis GO:0048701 90 0.020
regulation of vesicle mediated transport GO:0060627 9 0.020
Rat
response to hydrogen peroxide GO:0042542 3 0.020
Mouse Rat
metal ion transport GO:0030001 58 0.020
macromolecule modification GO:0043412 111 0.020
Human Yeast Mouse Rat Worm Fly
regulation of p38mapk cascade GO:1900744 1 0.020
purine nucleoside monophosphate catabolic process GO:0009128 4 0.020
sensory system development GO:0048880 76 0.019
positive regulation of secretion GO:0051047 1 0.019
release of sequestered calcium ion into cytosol GO:0051209 3 0.019
stem cell proliferation GO:0072089 4 0.019
inner ear development GO:0048839 126 0.019
nuclear export GO:0051168 1 0.019
myeloid cell development GO:0061515 32 0.019
Zebrafish
intracellular transport GO:0046907 32 0.019
regulation of kinase activity GO:0043549 15 0.019
negative regulation of dna metabolic process GO:0051053 4 0.019
microtubule organizing center organization GO:0031023 1 0.019
negative regulation of macromolecule metabolic process GO:0010605 76 0.019
Yeast
cell cycle process GO:0022402 53 0.019
Worm
negative regulation of cytoplasmic transport GO:1903650 2 0.018
neurotransmitter transport GO:0006836 2 0.018
blood vessel development GO:0001568 246 0.018
hard palate development GO:0060022 4 0.018
cellular component biogenesis GO:0044085 178 0.018
Yeast Rat
peptidyl threonine phosphorylation GO:0018107 1 0.018
regulation of sodium ion transport GO:0002028 2 0.018
positive regulation of gene expression GO:0010628 71 0.018
Human
protein polyubiquitination GO:0000209 4 0.018
dephosphorylation GO:0016311 11 0.018
positive regulation of secretion by cell GO:1903532 1 0.018
cytosolic calcium ion transport GO:0060401 3 0.018
cell substrate junction assembly GO:0007044 2 0.018
epithelial tube morphogenesis GO:0060562 148 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
regulation of cell substrate adhesion GO:0010810 1 0.017
cellular response to growth factor stimulus GO:0071363 39 0.017
negative regulation of kinase activity GO:0033673 4 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.017
oocyte maturation GO:0001556 4 0.017
signal transduction by phosphorylation GO:0023014 18 0.017
embryonic skeletal system development GO:0048706 97 0.017
regulation of cell morphogenesis GO:0022604 42 0.017
cellular response to nutrient levels GO:0031669 2 0.017
Yeast Mouse Fly
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.017
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.017
regulation of response to nutrient levels GO:0032107 1 0.017
Yeast
negative regulation of apoptotic process GO:0043066 55 0.017
Mouse
proepicardium development GO:0003342 4 0.017
establishment of synaptic vesicle localization GO:0097480 1 0.017
cellular catabolic process GO:0044248 27 0.017
Mouse Rat
alpha amino acid metabolic process GO:1901605 3 0.017
carbohydrate biosynthetic process GO:0016051 1 0.017
Yeast
regulation of reactive oxygen species metabolic process GO:2000377 2 0.017
embryonic heart tube morphogenesis GO:0003143 108 0.017
peptidyl serine modification GO:0018209 2 0.017
Mouse Worm
positive regulation of reproductive process GO:2000243 2 0.016
heart looping GO:0001947 94 0.016
nucleoside monophosphate catabolic process GO:0009125 4 0.016
cellular lipid catabolic process GO:0044242 3 0.016
protein complex subunit organization GO:0071822 46 0.016
Rat
dorsal convergence GO:0060030 14 0.016
response to drug GO:0042493 3 0.016
protein modification process GO:0036211 100 0.016
Human Yeast Mouse Rat Worm Fly
epidermis development GO:0008544 48 0.016
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 20 0.016
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.016
cellular hormone metabolic process GO:0034754 19 0.016
tissue homeostasis GO:0001894 25 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
regulation of cell motility GO:2000145 46 0.016
neuroblast proliferation GO:0007405 2 0.016
protein polymerization GO:0051258 4 0.016
blood vessel endothelial cell migration GO:0043534 18 0.016
adult behavior GO:0030534 2 0.016
mesenchymal cell development GO:0014031 78 0.016
negative regulation of cellular biosynthetic process GO:0031327 55 0.016
Yeast
lateral line system development GO:0048925 76 0.016
regulation of locomotion GO:0040012 55 0.016
carbohydrate homeostasis GO:0033500 1 0.016
Mouse
cellular response to starvation GO:0009267 1 0.016
Yeast Mouse Fly
neuromast development GO:0048884 46 0.016
embryo development ending in birth or egg hatching GO:0009792 271 0.015
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.015
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.015
mitotic cell cycle process GO:1903047 48 0.015
regulation of wound healing GO:0061041 2 0.015
response to growth factor GO:0070848 39 0.015
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.015
negative regulation of protein localization to nucleus GO:1900181 2 0.015
wnt signaling pathway GO:0016055 80 0.015
regulation of cellular component organization GO:0051128 86 0.015
Fly
positive regulation of apoptotic signaling pathway GO:2001235 1 0.015
anatomical structure homeostasis GO:0060249 36 0.015
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.015
cellular component assembly GO:0022607 170 0.015
Yeast Rat
regulation of system process GO:0044057 40 0.015
Zebrafish Fly
sequestering of calcium ion GO:0051208 3 0.015
embryonic organ development GO:0048568 381 0.015
myeloid cell homeostasis GO:0002262 56 0.015
Zebrafish
axis specification GO:0009798 43 0.015
negative regulation of catalytic activity GO:0043086 21 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
regulation of cellular localization GO:0060341 12 0.015
regulation of stem cell differentiation GO:2000736 4 0.015
regulation of anatomical structure morphogenesis GO:0022603 130 0.015
epithelial cell migration GO:0010631 25 0.014
positive regulation of cellular biosynthetic process GO:0031328 68 0.014
Yeast
regulation of cell activation GO:0050865 1 0.014
regulation of mrna processing GO:0050684 3 0.014
nuclear migration GO:0007097 3 0.014
calcium ion transport into cytosol GO:0060402 3 0.014
single organism intracellular transport GO:1902582 25 0.014
carbohydrate derivative metabolic process GO:1901135 61 0.014
muscle structure development GO:0061061 196 0.014
neuronal action potential GO:0019228 18 0.014
cell division GO:0051301 20 0.014
regulation of calcium ion transport GO:0051924 2 0.014
negative regulation of mitotic cell cycle GO:0045930 11 0.014
Worm
regulation of lipid catabolic process GO:0050994 2 0.014
Mouse
endodermal cell differentiation GO:0035987 19 0.014
transmission of nerve impulse GO:0019226 19 0.014
negative regulation of epithelial cell proliferation GO:0050680 1 0.014
positive regulation of muscle tissue development GO:1901863 1 0.014
cell fate commitment GO:0045165 99 0.014
cell cycle arrest GO:0007050 1 0.014
kupffer s vesicle development GO:0070121 50 0.014
hair cell differentiation GO:0035315 32 0.014
brain development GO:0007420 293 0.014
glycerolipid biosynthetic process GO:0045017 1 0.013
mapk cascade GO:0000165 18 0.013
regulation of cellular component movement GO:0051270 55 0.013
lipid biosynthetic process GO:0008610 22 0.013
Mouse
negative regulation of protein transport GO:0051224 3 0.013
regulation of neuron differentiation GO:0045664 56 0.013
fin regeneration GO:0031101 51 0.013
angiogenesis GO:0001525 158 0.013
negative regulation of cytokine production GO:0001818 1 0.013
single fertilization GO:0007338 3 0.013
regulation of cytokine mediated signaling pathway GO:0001959 3 0.013
spermatid development GO:0007286 2 0.013
sleep GO:0030431 1 0.013
regulation of protein kinase activity GO:0045859 15 0.013
glucose import GO:0046323 2 0.013
Rat
monocarboxylic acid biosynthetic process GO:0072330 12 0.013
activation of mapk activity GO:0000187 3 0.013
regulation of epithelial to mesenchymal transition GO:0010717 3 0.013
regulation of dna replication GO:0006275 3 0.013

prkaa1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.079
nervous system disease DOID:863 0 0.079
disease of metabolism DOID:0014667 0 0.069
inherited metabolic disorder DOID:655 0 0.069
cancer DOID:162 0 0.023
disease of cellular proliferation DOID:14566 0 0.023
organ system cancer DOID:0050686 0 0.018
immune system disease DOID:2914 0 0.013
hematopoietic system disease DOID:74 0 0.013